Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hexose:proton symporter activity	SLC45A2 SLC45A1	1.17e-05	3	40	2	GO:0009679
GeneOntologyMolecularFunction	D-glucose:proton symporter activity	SLC45A2 SLC45A1	1.17e-05	3	40	2	GO:0005356
GeneOntologyMolecularFunction	sucrose:monoatomic cation symporter activity	SLC45A2 SLC45A1	2.34e-05	4	40	2	GO:0009669
GeneOntologyMolecularFunction	anandamide 8,9 epoxidase activity	CYP2D7 CYP2D6	2.34e-05	4	40	2	GO:0062187
GeneOntologyMolecularFunction	anandamide 11,12 epoxidase activity	CYP2D7 CYP2D6	2.34e-05	4	40	2	GO:0062188
GeneOntologyMolecularFunction	sucrose transmembrane transporter activity	SLC45A2 SLC45A1	2.34e-05	4	40	2	GO:0008515
GeneOntologyMolecularFunction	sucrose:proton symporter activity	SLC45A2 SLC45A1	2.34e-05	4	40	2	GO:0008506
GeneOntologyMolecularFunction	oligosaccharide transmembrane transporter activity	SLC45A2 SLC45A1	2.34e-05	4	40	2	GO:0015157
GeneOntologyMolecularFunction	disaccharide transmembrane transporter activity	SLC45A2 SLC45A1	2.34e-05	4	40	2	GO:0015154
GeneOntologyMolecularFunction	steroid 21-monooxygenase activity	CYP2D7 CYP2D6	2.34e-05	4	40	2	GO:0004509
GeneOntologyMolecularFunction	progesterone 21-hydroxylase activity	CYP2D7 CYP2D6	2.34e-05	4	40	2	GO:0106309
GeneOntologyMolecularFunction	anandamide 14,15 epoxidase activity	CYP2D7 CYP2D6	5.84e-05	6	40	2	GO:0062189
GeneOntologyMolecularFunction	anandamide epoxidase activity	CYP2D7 CYP2D6	5.84e-05	6	40	2	GO:0062186
GeneOntologyMolecularFunction	carbohydrate:proton symporter activity	SLC45A2 SLC45A1	1.09e-04	8	40	2	GO:0005351
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC45A2 SLC45A1	5.22e-04	17	40	2	GO:0005402
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC45A2 SLC45A1	1.14e-03	25	40	2	GO:0055056
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC45A2 SLC45A1	1.14e-03	25	40	2	GO:0015149
GeneOntologyMolecularFunction	solute:proton symporter activity	SLC45A2 SLC45A1	1.14e-03	25	40	2	GO:0015295
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP2D7 CYP2D6	1.33e-03	27	40	2	GO:0008391
GeneOntologyMolecularFunction	monosaccharide transmembrane transporter activity	SLC45A2 SLC45A1	1.33e-03	27	40	2	GO:0015145
GeneOntologyMolecularFunction	sugar transmembrane transporter activity	SLC45A2 SLC45A1	1.54e-03	29	40	2	GO:0051119
GeneOntologyMolecularFunction	steroid hydroxylase activity	CYP2D7 CYP2D6	2.11e-03	34	40	2	GO:0008395
GeneOntologyMolecularFunction	aromatase activity	CYP2D7 CYP2D6	2.23e-03	35	40	2	GO:0070330
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP2D7 CYP2D6	2.91e-03	40	40	2	GO:0016709
GeneOntologyMolecularFunction	carbohydrate transmembrane transporter activity	SLC45A2 SLC45A1	3.20e-03	42	40	2	GO:0015144
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP2D7 CYP2D6	4.34e-03	49	40	2	GO:0016712
GeneOntologyMolecularFunction	proton transmembrane transporter activity	SLC45A2 STING1 SLC45A1	6.28e-03	188	40	3	GO:0015078
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC45A2 STING1 SLC45A1 KCNQ5 PKD1	7.97e-03	627	40	5	GO:0022890
GeneOntologyBiologicalProcess	serotonin biosynthetic process from tryptophan	CYP2D7 CYP2D6	9.90e-06	3	38	2	GO:0006587
GeneOntologyBiologicalProcess	oligosaccharide transport	SLC45A2 SLC45A1	1.98e-05	4	38	2	GO:0015772
GeneOntologyBiologicalProcess	sucrose transport	SLC45A2 SLC45A1	1.98e-05	4	38	2	GO:0015770
GeneOntologyBiologicalProcess	disaccharide transport	SLC45A2 SLC45A1	1.98e-05	4	38	2	GO:0015766
GeneOntologyBiologicalProcess	aromatic amino acid metabolic process	SLC45A2 CYP2D7 CYP2D6	8.29e-05	46	38	3	GO:0009072
GeneOntologyBiologicalProcess	serotonin biosynthetic process	CYP2D7 CYP2D6	9.19e-05	8	38	2	GO:0042427
GeneOntologyBiologicalProcess	indole-containing compound biosynthetic process	CYP2D7 CYP2D6	1.47e-04	10	38	2	GO:0042435
GeneOntologyBiologicalProcess	primary amino compound biosynthetic process	CYP2D7 CYP2D6	1.47e-04	10	38	2	GO:1901162
GeneOntologyBiologicalProcess	phenol-containing compound biosynthetic process	SLC45A2 CYP2D7 CYP2D6	1.58e-04	57	38	3	GO:0046189
GeneOntologyBiologicalProcess	oxidative demethylation	CYP2D7 CYP2D6	2.16e-04	12	38	2	GO:0070989
GeneOntologyBiologicalProcess	tryptophan metabolic process	CYP2D7 CYP2D6	2.97e-04	14	38	2	GO:0006568
GeneOntologyBiologicalProcess	indolalkylamine metabolic process	CYP2D7 CYP2D6	3.90e-04	16	38	2	GO:0006586
GeneOntologyBiologicalProcess	dopamine biosynthetic process	CYP2D7 CYP2D6	4.42e-04	17	38	2	GO:0042416
GeneOntologyBiologicalProcess	serotonin metabolic process	CYP2D7 CYP2D6	4.96e-04	18	38	2	GO:0042428
GeneOntologyCellularComponent	Golgi membrane	ZDHHC2 GFY PRKCI STING1 HS6ST1 UGCG PKD1	2.80e-04	721	38	7	GO:0000139
Domain	GAGE	XAGE5 XAGE2 GAGE2A	7.36e-06	19	38	3	SM01379
Domain	GAGE	XAGE5 XAGE2 GAGE2A	7.36e-06	19	38	3	IPR031320
Domain	GAGE	XAGE5 XAGE2 GAGE2A	1.53e-05	24	38	3	PF05831
Domain	GAGE_fam	XAGE5 XAGE2 GAGE2A	1.73e-05	25	38	3	IPR008625
Domain	LDLRA_1	TMPRSS9 PKD1	4.29e-03	48	38	2	PS01209
Domain	LDLRA_2	TMPRSS9 PKD1	4.46e-03	49	38	2	PS50068
Domain	MFS	SLC45A2 SLC45A1	1.07e-02	77	38	2	IPR011701
Domain	MFS_1	SLC45A2 SLC45A1	1.07e-02	77	38	2	PF07690
Pathway	REACTOME_CYP2E1_REACTIONS	CYP2D7 CYP2D6	2.30e-04	12	27	2	MM14847
Pathway	REACTOME_BIOSYNTHESIS_OF_MARESINS	CYP2D7 CYP2D6	2.30e-04	12	27	2	MM15616
Pathway	BIOCARTA_RACC_PATHWAY	GNAS KCNQ5	3.65e-04	15	27	2	M22002
Pathway	REACTOME_MISCELLANEOUS_SUBSTRATES	CYP2D7 CYP2D6	5.30e-04	18	27	2	MM14843
Pathway	REACTOME_FATTY_ACIDS	CYP2D7 CYP2D6	5.30e-04	18	27	2	MM14841
Pathway	REACTOME_BIOSYNTHESIS_OF_SPECIALIZED_PRORESOLVING_MEDIATORS_SPMS	CYP2D7 CYP2D6	7.97e-04	22	27	2	MM15614
Pathway	REACTOME_SURFACTANT_METABOLISM	ZDHHC2 P2RY2	8.72e-04	23	27	2	MM15279
Pathway	REACTOME_XENOBIOTICS	CYP2D7 CYP2D6	1.03e-03	25	27	2	MM14846
Pubmed	Characterization of Cyp2d22, a novel cytochrome P450 expressed in mouse mammary cells.	CYP2D7 CYP2D6	1.49e-06	2	43	2	11032406
Pubmed	Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.	CYP2D7 CYP2D6	1.49e-06	2	43	2	3123997
Pubmed	T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells.	GNAS TAS1R3	1.49e-06	2	43	2	28472098
Pubmed	The expression of CYP2D22, an ortholog of human CYP2D6, in mouse striatum and its modulation in 1-methyl 4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease phenotype and nicotine-mediated neuroprotection.	CYP2D7 CYP2D6	1.49e-06	2	43	2	19594327
Pubmed	Coding-noncoding gene expression in intrahepatic cholangiocarcinoma.	CYP2D7 CYP2D6	1.49e-06	2	43	2	26297049
Pubmed	Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.	CYP2D7 CYP2D6	1.49e-06	2	43	2	25808902
Pubmed	Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?	CYP2D7 CYP2D6	1.49e-06	2	43	2	11207030
Pubmed	A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.	CYP2D7 CYP2D6	1.49e-06	2	43	2	15051713
Pubmed	Polymorphisms of genes CYP2D6, ADRB1 and GNAS1 in pharmacokinetics and systemic effects of ophthalmic timolol. A pilot study.	GNAS CYP2D6	4.48e-06	3	43	2	16315032
Pubmed	The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.	CYP2D7 CYP2D6	4.48e-06	3	43	2	2574001
Pubmed	Umami taste receptor functions as an amino acid sensor via Gαs subunit in N1E-115 neuroblastoma cells.	GNAS TAS1R3	4.48e-06	3	43	2	22189795
Pubmed	Identification of the primary gene defect at the cytochrome P450 CYP2D locus.	CYP2D7 CYP2D6	4.48e-06	3	43	2	1978251
Pubmed	Cutting edge: DNA sensing via the STING adaptor in myeloid dendritic cells induces potent tolerogenic responses.	SIGLEC1 STING1	4.48e-06	3	43	2	23986532
Pubmed	CD169+ macrophages orchestrate plasmacytoid dendritic cell arrest and retention for optimal priming in the bone marrow of malaria-infected mice.	SIGLEC1 STING1	1.49e-05	5	43	2	36278864
Pubmed	Polymorphism of metabolic genes and susceptibility to occupational chronic manganism.	CYP2D7 CYP2D6	2.23e-05	6	43	2	12171760
Pubmed	STING-Licensed Macrophages Prime Type I IFN Production by Plasmacytoid Dendritic Cells in the Bone Marrow during Severe Plasmodium yoelii Malaria.	SIGLEC1 STING1	2.23e-05	6	43	2	27792766
Pubmed	The XAGE family of cancer/testis-associated genes: alignment and expression profile in normal tissues, melanoma lesions and Ewing's sarcoma.	XAGE5 XAGE2	3.12e-05	7	43	2	11992404
Pubmed	Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.	PRKCI PKD1	3.12e-05	7	43	2	24153433
Pubmed	Effects of infection of MRSA on the expression and activity of renal cytochrome P450s in mice.	CYP2D7 CYP2D6	3.12e-05	7	43	2	30944282
Pubmed	A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.	GAGE2B GAGE2A	5.35e-05	9	43	2	7544395
Pubmed	Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.	TAS1R3 PKD1	6.68e-05	10	43	2	16805797
Pubmed	Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression.	PRKCI GNAS	9.78e-05	12	43	2	25916881
Pubmed	The DNA sequence of the human X chromosome.	XAGE5 XAGE2 GAGE2B GAGE10 GAGE2A	1.43e-04	407	43	5	15772651
Pubmed	Identification of PSD-95 palmitoylating enzymes.	ZDHHC2 GNAS	2.01e-04	17	43	2	15603741
Pubmed	An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.	GAGE2B GAGE10	2.80e-04	20	43	2	18179644
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DISP2 SLC45A1 KMT2B ZNF865 TMEM8B CDK13 PKD1	3.80e-04	1105	43	7	35748872
Pubmed	Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription.	KMT2B HESX1	4.40e-04	25	43	2	25664857
Pubmed	Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.	STING1 P2RY2	5.93e-04	29	43	2	34678150
Cytoband	Ensembl 112 genes in cytogenetic band chrXp11	XAGE5 XAGE2 GAGE10 GAGE2A	4.29e-04	377	43	4	chrXp11
Cytoband	Xp11.22	XAGE5 XAGE2	1.19e-03	54	43	2	Xp11.22
Cytoband	16p13.3	ZNF200 NPW PKD1	1.56e-03	244	43	3	16p13.3
Cytoband	Xp11.23	GAGE2B GAGE2A	3.62e-03	95	43	2	Xp11.23
GeneFamily	Cytochrome P450 family 2	CYP2D7 CYP2D6	1.24e-03	35	27	2	1001
Drug	p-hydroxymexiletine	GNAS CYP2D7 CYP2D6	4.52e-07	9	41	3	CID000093286
Drug	NMBA	SLC45A2 PRKCI CYP2D7 CYP2D6	1.17e-06	44	41	4	CID000023471
Drug	2-Tbmbfd	SLC45A2 CYP2D7 CYP2D6	1.18e-06	12	41	3	CID000126928
Drug	cupreidine	CYP2D7 CYP2D6	3.16e-06	2	41	2	CID000051196
Drug	3-methoxyphenethylamine	CYP2D7 CYP2D6	3.16e-06	2	41	2	CID000074866
Drug	iodosylbenzene	ZDHHC2 CYP2D7 CYP2D6	4.34e-06	18	41	3	CID000092125
Drug	chlorpromazine N-oxide	CYP2D7 CYP2D6	9.48e-06	3	41	2	CID000443037
Drug	2,4,6-trimethylbenzaldoxime	CYP2D7 CYP2D6	9.48e-06	3	41	2	CID000283782
Drug	O-demethyl encainide	CYP2D7 CYP2D6	9.48e-06	3	41	2	CID000054736
Drug	metyrapone	SLC45A2 GNAS CYP2D7 CYP2D6 UGCG	1.69e-05	179	41	5	CID000004174
Drug	4,4'-difluorobenzophenone	CYP2D7 CYP2D6	1.89e-05	4	41	2	CID000009582
Drug	Z-10	CYP2D7 CYP2D6	1.89e-05	4	41	2	CID000477529
Drug	1-(1-phenylcyclohexyl)-4-piperidinol	CYP2D7 CYP2D6	1.89e-05	4	41	2	CID000098840
Drug	desethylaprindine	CYP2D7 CYP2D6	1.89e-05	4	41	2	CID000162697
Drug	BP-7,8-oxide	SLC45A2 CYP2D7 CYP2D6	2.59e-05	32	41	3	CID000037455
Drug	eptapirone	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000208928
Drug	Koe 1801	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000129632
Drug	2Cmp	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000023392
Drug	L-754,394	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID005481990
Drug	oxosparteine	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000097492
Drug	threohydrobupropion	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000000445
Drug	4-hydroxyochratoxin A	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000114713
Drug	fenproporex	CYP2D7 CYP2D6	3.15e-05	5	41	2	CID000061810
Drug	luliconazole	CYP2D7 CYP2D6 P2RY2	3.41e-05	35	41	3	CID003003141
Drug	8-Methylxanthine	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000087061
Drug	AC1L45F6	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000150982
Drug	KRM1674	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000126235
Drug	5-dehydrosparteine	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000160614
Drug	nitroguanidine	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000011174
Drug	10-hydroxyochratoxin A	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000135115
Drug	7-hydroxychlorpromazine	CYP2D7 CYP2D6	4.72e-05	6	41	2	CID000016414
Drug	furafylline	SLC45A2 CYP2D7 CYP2D6	5.51e-05	41	41	3	CID000003433
Drug	alpha-naphthoflavone	SLC45A2 CYP2D7 CYP2D6 HESX1	5.99e-05	118	41	4	CID000011790
Drug	nefazodone	GNAS CYP2D7 CYP2D6	6.36e-05	43	41	3	CID000004449
Drug	Ben 101	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID000090766
Drug	azoprocarbazine	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID000075230
Drug	quinidine-N-oxide	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID000050979
Drug	2-sulfamoylacetylphenol	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID000194588
Drug	phenyl isocyanide	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID000013606
Drug	ICI-199,441	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID003082717
Drug	5,6-Dehydro-sparteine	CYP2D7 CYP2D6	6.61e-05	7	41	2	CID000523578
Drug	sulfaphenazole	SLC45A2 CYP2D7 CYP2D6	6.82e-05	44	41	3	CID000005335
Drug	promethazine	CYP2D7 CYP2D6 RNF103	7.80e-05	46	41	3	CID000004927
Drug	bufuralol	SLC45A2 CYP2D7 CYP2D6	7.80e-05	46	41	3	CID000071733
Drug	AC1L1R04	SLC45A2 CYP2D7 CYP2D6	8.32e-05	47	41	3	CID000008439
Drug	MPBP	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000129775
Drug	pirprofen	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000035935
Drug	phenmetrazine	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000004762
Drug	AC1L9DBW	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000442742
Drug	HCBz	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000196604
Drug	beta-site	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000003914
Drug	hydroxynortriptyline	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID005352542
Drug	L-754394	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000153982
Drug	B.W.306U	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000000446
Drug	Z H-H	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000004657
Drug	3,4-dihydroxymethamphetamine	CYP2D7 CYP2D6	8.80e-05	8	41	2	CID000161126
Drug	2cgu	SLC45A2 CYP2D7 CYP2D6	8.86e-05	48	41	3	CID003506204
Drug	nitro-L	SLC45A2 CYP2D7 CYP2D6	8.86e-05	48	41	3	CID000006849
Drug	sulfamethazine	SLC45A2 CYP2D7 CYP2D6	8.86e-05	48	41	3	CID000005327
Drug	nifedipine	SLC45A2 PRKCI CYP2D7 CYP2D6 P2RY2 PKD1	9.27e-05	415	41	6	CID000004485
Drug	NSC150531	PRKCI CYP2D7 CYP2D6	9.43e-05	49	41	3	CID000004475
Drug	hydroquinidine hydrochloride	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID000003649
Drug	norethylmorphine	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID005464196
Drug	O-demethylmetoprolol	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID000162181
Drug	guanoxan	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID000016564
Drug	1-chlorobutane	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID000008005
Drug	CP-101,606	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID000219101
Drug	AC1O3M98	CYP2D7 CYP2D6	1.13e-04	9	41	2	CID006332100
Drug	resorufin	SLC45A2 CYP2D7 CYP2D6	1.19e-04	53	41	3	CID000069462
Drug	paraxanthine	SLC45A2 CYP2D7 CYP2D6	1.19e-04	53	41	3	CID000004687
Drug	Sulf	CYP2D7 CYP2D6 HS6ST1	1.26e-04	54	41	3	CID003083599
Drug	phenacetin	SLC45A2 CYP2D7 CYP2D6	1.33e-04	55	41	3	CID000004754
Drug	tryptophan pyrolysate	SLC45A2 STING1 PKD1	1.41e-04	56	41	3	CID005284475
Drug	orphenadrine	SLC45A2 CYP2D7 CYP2D6	1.41e-04	56	41	3	CID000004601
Drug	AC1LCF1O	CYP2D7 CYP2D6	1.41e-04	10	41	2	CID000627285
Drug	benzaldehyde oxime	CYP2D7 CYP2D6	1.41e-04	10	41	2	CID000012143
Drug	2-hydroxydesipramine	CYP2D7 CYP2D6	1.41e-04	10	41	2	CID000121249
Drug	norchlorpromazine	CYP2D7 CYP2D6	1.41e-04	10	41	2	CID000062875
Drug	AC1L1IDP	CYP2D7 CYP2D6	1.41e-04	10	41	2	CID000004535
Drug	4-hydroxydebrisoquine	CYP2D7 CYP2D6	1.41e-04	10	41	2	CID000107669
Drug	9-benzyladenine	CYP2D7 CYP2D6	1.72e-04	11	41	2	CID000020262
Drug	8-hydroxycarteolol	CYP2D7 CYP2D6	1.72e-04	11	41	2	CID000124688
Drug	4-hydroxy-3-methoxymethamphetamine	CYP2D7 CYP2D6	1.72e-04	11	41	2	CID003081137
Drug	sphondin	CYP2D7 CYP2D6	1.72e-04	11	41	2	CID000108104
Drug	naphthohydroquinone	CYP2D7 CYP2D6	1.72e-04	11	41	2	CID000011305
Drug	vindoline	CYP2D7 CYP2D6	1.72e-04	11	41	2	CID000016596
Drug	17-ODYA	CYP2D7 CYP2D6 P2RY2	1.73e-04	60	41	3	CID000001449
Drug	lidocaine	PRKCI CYP2D7 CYP2D6 MMP23B	1.94e-04	160	41	4	CID000003676
Drug	chlorzoxazone	SLC45A2 CYP2D7 CYP2D6	2.00e-04	63	41	3	CID000002733
Drug	D02861	CYP2D7 CYP2D6	2.06e-04	12	41	2	CID011954281
Drug	phenylacetone	CYP2D7 CYP2D6	2.06e-04	12	41	2	CID000007678
Drug	methoxyphenamine	CYP2D7 CYP2D6	2.06e-04	12	41	2	CID000004117
Drug	2-ketoarginine	GNAS UGCG	2.06e-04	12	41	2	CID000000558
Drug	16 alpha-hydroxytestosterone	CYP2D7 CYP2D6	2.06e-04	12	41	2	CID000065545
Drug	alprenolol	NPW CYP2D7 CYP2D6	2.09e-04	64	41	3	CID000002119
Drug	halothane	SLC45A2 PRKCI CYP2D7 CYP2D6 PKD1	2.41e-04	314	41	5	CID000003562
Drug	phenylpropane	SLC45A2 SIGLEC1	2.44e-04	13	41	2	CID000007668
Drug	AC1L1JL9	CYP2D7 CYP2D6	2.44e-04	13	41	2	CID000005091
Drug	AC1L18GM	CYP2D7 CYP2D6	2.44e-04	13	41	2	CID000000092
Drug	AC1L1N5A	CYP2D7 CYP2D6	2.44e-04	13	41	2	CID000006717
Disease	solanidine measurement	CYP2D7 CYP2D6	8.67e-06	4	36	2	EFO_0800966
Disease	Dystonia, Limb	KMT2B CYP2D6	1.95e-04	17	36	2	C0751093
Disease	Dystonia, Diurnal	KMT2B CYP2D6	1.95e-04	17	36	2	C0393610
Disease	Dystonia, Paroxysmal	KMT2B CYP2D6	2.19e-04	18	36	2	C0393588
Disease	glucose homeostasis measurement, acute insulin response measurement	ZDHHC2 P2RY2	2.19e-04	18	36	2	EFO_0006831, EFO_0006896
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	CYP2D7 CYP2D6	3.93e-04	24	36	2	EFO_0003761, EFO_0005658
Disease	Kallmann Syndrome	HS6ST1 HESX1	4.62e-04	26	36	2	C0162809
Disease	Heschl's gyrus morphology measurement	DISP2 TMEM121B	1.92e-03	53	36	2	EFO_0005852

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSRSRRYPWRRSADR	GNAS	571	P84996
RTGRFCRDFWRVRNP	EXOC3L1	566	Q86VI1
RYLARGCARRARGRW	DISP2	646	A7MBM2
SWRRSRSPYSPVLRR	CDK13	391	Q14004
PFRCRWKLAPRYSRR	CAPN14	6	A8MX76
RRGARRWRKLYCANG	PRKCI	126	P41743
RRSPYLWRRALRAAA	NPW	56	Q8N729
AFPRAWYRRSIARRL	KIAA1109	4266	Q2LD37
CRYRGWQGRLRFARK	KCNQ5	186	Q9NR82
RELSWYRGRRPRTAF	HESX1	101	Q9UBX0
MSWRGRSTYRPRPRR	GAGE2D;	1	Q9UEU5
MSWRGRSTYRPRPRR	GAGE2A	1	Q6NT46
RRRCWYRCRILEYRP	KMT2B	1771	Q9UMN6
SLRWGRARYARRVAG	P2RY2	141	P41231
TCYRPNRRETWLFSR	HS6ST1	126	O60243
AELASRYWGRRRALP	DOCK8-AS1	226	Q5T8R8
LLWCLYRRAARQRPF	GFY	426	I3L273
LARYGPAWREQRRFS	CYP2D6	121	P10635
MSWRGRSTYRPRPRR	GAGE10	1	A6NGK3
PTISWRTGRYRLRCG	UGCG	371	Q16739
CSSDPRYCRRRGWVR	RNF103	156	O00237
RYCRRRGWVRSTLIM	RNF103	161	O00237
AWSDRCTSRFGRRRP	SLC45A1	176	Q9Y2W3
ASDHCRSRWGRRRPY	SLC45A2	91	Q9UMX9
RWEVYRTASCQRPGR	PKD1	2186	P98161
YWRTVRACLGCPLRR	STING1	81	Q86WV6
RRRGCAPSPRCRWGY	TMEM121B	186	Q9BXQ6
LGRLYGSRRSCLWRS	TMEM151B	476	Q8IW70
SRSRGWYSRGRTRSR	NKTR	1356	P30414
RRRYTLTPARLRWDH	MMP23B	76	O75900
YWRRRPKRLSAVVCA	MRGPRF	151	Q96AM1
MSWRGRSTYRPRPRR	GAGE2B	1	Q13066
ASGLRYWSRRLRPAA	HIBADH	11	P31937
EVGTRRGCRRYRWEL	CMTM2	61	Q8TAZ6
LSRYGPAWREQRRFS	CYP2D7	121	A0A087X1C5
WSPERSTRCFRRRSR	TAS1R3	546	Q7RTX0
CGRGFLRSWYLRQHR	ZNF865	881	P0CJ78
MSWRGRSTYRPRPRR	XAGE2	1	Q96GT9
DRCWGPLRRVDAYRI	TMEM104	196	Q8NE00
RRPGVYARVTRLRDW	TMPRSS9	416	Q7Z410
VRRRHCYPPTWRRWL	TMEM8B	366	A6NDV4
LLGLGACYTWRRRRV	SIGLEC1	1656	Q9BZZ2
CYPVIRCLLRRRGWV	TTLL3	26	Q9Y4R7
ALTRNRRTRRWYTCP	ZNF200	241	P98182
PGSSARRRCRRVLYW	ZDHHC2	6	Q9UIJ5
RRRCRRVLYWIPVVF	ZDHHC2	11	Q9UIJ5
MSWRGRRYRPRRCLR	XAGE5	1	Q8WWM1