Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	2.07e-05	3	53	2	GO:0018858
GeneOntologyMolecularFunction	C-acyltransferase activity	SPTLC1 ACSM2A ACSM2B	2.27e-05	21	53	3	GO:0016408
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	4.13e-05	4	53	2	GO:0102391
GeneOntologyMolecularFunction	ubiquitin conjugating enzyme activity	UBE2L3 UBE2L5 TAF1	1.29e-04	37	53	3	GO:0061631
GeneOntologyMolecularFunction	acyltransferase activity	ELOVL4 NEDD4L UBE2L3 SPTLC1 UBE2L5 TAF1 DCST1 ACSM2A ACSM2B	1.82e-04	775	53	9	GO:0016746
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	1.92e-04	8	53	2	GO:0004321
GeneOntologyMolecularFunction	ubiquitin-like protein conjugating enzyme activity	UBE2L3 UBE2L5 TAF1	2.02e-04	43	53	3	GO:0061650
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM2A ACSM2B	3.74e-04	11	53	2	GO:0031956
GeneOntologyMolecularFunction	1-phosphatidylinositol-3-kinase activity	PIK3C2B PIK3R1	3.74e-04	11	53	2	GO:0016303
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	ELOVL4 SPTLC1 TAF1 ACSM2A ACSM2B	4.15e-04	238	53	5	GO:0016747
GeneOntologyMolecularFunction	ligase activity	FARSA UBE2L5 ACSM2A ACSM2B	1.17e-03	174	53	4	GO:0016874
GeneOntologyMolecularFunction	telomerase RNA binding	TENT4B GAR1	1.99e-03	25	53	2	GO:0070034
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	PIK3C2B PIK3R1	2.16e-03	26	53	2	GO:0052742
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSM2A ACSM2B	2.16e-03	26	53	2	GO:0015645
GeneOntologyMolecularFunction	CoA-ligase activity	ACSM2A ACSM2B	2.33e-03	27	53	2	GO:0016405
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	MAP2K4 CSF1R PIK3C2B PIK3R1 LTBP1 TAF1 PRKG2	2.57e-03	709	53	7	GO:0016773
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSM2A ACSM2B	3.06e-03	31	53	2	GO:0016878
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	MAP2K4 TENT4B CSF1R PIK3C2B PIK3R1 LTBP1 TAF1 PRKG2	3.12e-03	938	53	8	GO:0016772
GeneOntologyMolecularFunction	organic acid:sodium symporter activity	SLC6A11 SLC23A2	3.89e-03	35	53	2	GO:0005343
GeneOntologyMolecularFunction	kinase activity	MAP2K4 CSF1R PIK3C2B PIK3R1 LTBP1 TAF1 PRKG2	3.89e-03	764	53	7	GO:0016301
GeneOntologyMolecularFunction	protein heterodimerization activity	SYT3 PIK3R1 AGTR1 TAF1 GABBR2	4.02e-03	398	53	5	GO:0046982
GeneOntologyMolecularFunction	protein dimerization activity	ZBTB38 CCDC66 CSF1R SYT3 PIK3R1 AGTR1 TAF1 GABBR2 ECT2	4.12e-03	1205	53	9	GO:0046983
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSM2A ACSM2B	5.30e-03	41	53	2	GO:0016877
GeneOntologyMolecularFunction	lipid kinase activity	PIK3C2B PIK3R1	5.30e-03	41	53	2	GO:0001727
GeneOntologyCellularComponent	Flemming body	OR2A7 CCDC66 OR2A4	1.10e-04	36	54	3	GO:0090543
GeneOntologyCellularComponent	cleavage furrow	OR2A7 OR2A4 ECT2	5.27e-04	61	54	3	GO:0032154
GeneOntologyCellularComponent	mitotic spindle midzone	OR2A7 OR2A4	7.68e-04	16	54	2	GO:1990023
MousePheno	abnormal circulating chloride level	FARSA GAR1 CARF ASCC2 ACSM2A ACSM2B	3.61e-06	156	38	6	MP:0003018
MousePheno	abnormal chloride level	FARSA GAR1 CARF ASCC2 ACSM2A ACSM2B	6.77e-06	174	38	6	MP:0012007
MousePheno	decreased circulating chloride level	FARSA GAR1 ACSM2A ACSM2B	2.79e-05	65	38	4	MP:0003020
Domain	BROMODOMAIN_1	PBRM1 ASH1L TAF1	1.40e-04	37	51	3	PS00633
Domain	Bromodomain	PBRM1 ASH1L TAF1	1.51e-04	38	51	3	PF00439
Domain	BROMODOMAIN_2	PBRM1 ASH1L TAF1	1.90e-04	41	51	3	PS50014
Domain	BROMO	PBRM1 ASH1L TAF1	2.04e-04	42	51	3	SM00297
Domain	Bromodomain	PBRM1 ASH1L TAF1	2.04e-04	42	51	3	IPR001487
Domain	-	PBRM1 ASH1L TAF1	2.04e-04	42	51	3	1.20.920.10
Domain	BAH	PBRM1 ASH1L	3.96e-04	11	51	2	SM00439
Domain	BAH	PBRM1 ASH1L	3.96e-04	11	51	2	PF01426
Domain	BAH	PBRM1 ASH1L	3.96e-04	11	51	2	PS51038
Domain	BAH_dom	PBRM1 ASH1L	3.96e-04	11	51	2	IPR001025
Domain	HMG_BOX_2	PBRM1 TAF1 SOX13	4.31e-04	54	51	3	PS50118
Domain	C2	NEDD4L SYT3 PIK3C2B SYTL2	4.48e-04	131	51	4	PF00168
Domain	C2	NEDD4L SYT3 PIK3C2B SYTL2	5.30e-04	137	51	4	SM00239
Domain	C2	NEDD4L SYT3 PIK3C2B SYTL2	6.07e-04	142	51	4	PS50004
Domain	-	NEDD4L SYT3 PIK3C2B SYTL2	7.08e-04	148	51	4	2.60.40.150
Domain	AMP-bd_C	ACSM2A ACSM2B	9.68e-04	17	51	2	IPR025110
Domain	AMP-binding_C	ACSM2A ACSM2B	9.68e-04	17	51	2	PF13193
Domain	C2_dom	NEDD4L SYT3 PIK3C2B SYTL2	1.04e-03	164	51	4	IPR000008
Domain	Bromodomain_CS	PBRM1 TAF1	2.28e-03	26	51	2	IPR018359
Domain	AMP-binding_CS	ACSM2A ACSM2B	2.28e-03	26	51	2	IPR020845
Domain	AMP_BINDING	ACSM2A ACSM2B	2.64e-03	28	51	2	PS00455
Domain	AMP-binding	ACSM2A ACSM2B	3.03e-03	30	51	2	PF00501
Domain	AMP-dep_Synth/Lig	ACSM2A ACSM2B	3.03e-03	30	51	2	IPR000873
Domain	HMG_box	PBRM1 SOX13	9.22e-03	53	51	2	PF00505
Domain	HMG	PBRM1 SOX13	9.56e-03	54	51	2	SM00398
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	2.37e-06	2	54	2	16521160
Pubmed	Evidence that phosphatidylinositol 3-kinase- and mitogen-activated protein kinase kinase-4/c-Jun NH2-terminal kinase-dependent Pathways cooperate to maintain lung cancer cell survival.	MAP2K4 PIK3R1	2.37e-06	2	54	2	12714585
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	2.37e-06	2	54	2	19634011
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	2.37e-06	2	54	2	29948332
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	CCDC66 PNN PIK3C2B ATAD5 ASCC2	6.66e-06	169	54	5	31462741
Pubmed	Regulation of Nedd4-2 self-ubiquitination and stability by a PY motif located within its HECT-domain.	NEDD4L UBE2L3	7.09e-06	3	54	2	18498246
Pubmed	Sequential activation of phoshatidylinositol 3-kinase and phospholipase C-gamma2 by the M-CSF receptor is necessary for differentiation signaling.	CSF1R PIK3R1	7.09e-06	3	54	2	9312046
Pubmed	Elevated intracellular Na+ and osmolarity stimulate catalytic activity of the ubiquitin ligase Nedd4-2.	NEDD4L UBE2L3	7.09e-06	3	54	2	35858421
Pubmed	EP24.15 interacts with the angiotensin II type I receptor and bradykinin B2 receptor.	THOP1 AGTR1	7.09e-06	3	54	2	15376229
Pubmed	Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.	OR2A7 OR2A4	7.09e-06	3	54	2	27315375
Pubmed	Genome-wide interrogation of longitudinal FEV1 in children with asthma.	SLC6A11 ZBTB38	7.09e-06	3	54	2	25221879
Pubmed	A zonal organization of odorant receptor gene expression in the olfactory epithelium.	OR2A7 OR2A4	1.42e-05	4	54	2	7683976
Pubmed	SH2 domains of the p85 alpha subunit of phosphatidylinositol 3-kinase regulate binding to growth factor receptors.	CSF1R PIK3R1	1.42e-05	4	54	2	1372092
Pubmed	Association between phosphatidylinositol-3 kinase, Cbl and other tyrosine phosphorylated proteins in colony-stimulating factor-1-stimulated macrophages.	CSF1R PIK3R1	1.42e-05	4	54	2	8947469
Pubmed	Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.	ACSM2A ACSM2B	1.42e-05	4	54	2	32830538
Pubmed	Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.	NEDD4L PIK3R1	2.36e-05	5	54	2	25157163
Pubmed	Autotaxin stimulates urokinase-type plasminogen activator expression through phosphoinositide 3-kinase-Akt-nuclear [corrected] factor kappa B signaling cascade in human melanoma cells.	PIK3R1 ENPP2	2.36e-05	5	54	2	17013094
Pubmed	The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase.	PIK3C2B PIK3R1	2.36e-05	5	54	2	9223670
Pubmed	M-CSF regulates the cytoskeleton via recruitment of a multimeric signaling complex to c-Fms Tyr-559/697/721.	CSF1R PIK3R1	3.54e-05	6	54	2	17420256
Pubmed	β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.	NEDD4L UBE2L3	3.54e-05	6	54	2	29964046
Pubmed	CSF-1 stimulated multiubiquitination of the CSF-1 receptor and of Cbl follows their tyrosine phosphorylation and association with other signaling proteins.	CSF1R PIK3R1	3.54e-05	6	54	2	10025673
Pubmed	The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading.	CSF1R PIK3R1	3.54e-05	6	54	2	15735664
Pubmed	Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo.	PIK3C2B PIK3R1	3.54e-05	6	54	2	8084603
Pubmed	Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5.	NEDD4L UBE2L3	3.54e-05	6	54	2	8576257
Pubmed	Linkage mapping of Csrp to proximal mouse chromosome 3.	AGTR1 SI	3.54e-05	6	54	2	9457685
Pubmed	Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase.	NEDD4L UBE2L3	3.54e-05	6	54	2	28461335
Pubmed	A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases.	NEDD4L UBE2L3	4.94e-05	7	54	2	30587574
Pubmed	Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.	NEDD4L UBE2L3	4.94e-05	7	54	2	20051513
Pubmed	HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK.	NEDD4L UBE2L3	4.94e-05	7	54	2	20086093
Pubmed	Separation and characterization of the activated pool of colony-stimulating factor 1 receptor forming distinct multimeric complexes with signalling molecules in macrophages.	CSF1R PIK3R1	4.94e-05	7	54	2	10330148
Pubmed	The ubiquitin-protein ligases Nedd4 and Nedd4-2 show similar ubiquitin-conjugating enzyme specificities.	NEDD4L UBE2L3	4.94e-05	7	54	2	16337426
Pubmed	The E3 Ubiquitin Ligase NEDD4L Targets OGG1 for Ubiquitylation and Modulates the Cellular DNA Damage Response.	NEDD4L UBE2L3	4.94e-05	7	54	2	33282879
Pubmed	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	ZBTB38 ATAD5 LTBP1 PRKG2	4.95e-05	129	54	4	23563607
Pubmed	Saturation mutagenesis defines novel mouse models of severe spine deformity.	OR2A7 OR2A4	6.59e-05	8	54	2	34142127
Pubmed	Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.	NEDD4L UBE2L3	6.59e-05	8	54	2	17719543
Pubmed	Assembly and specific recognition of k29- and k33-linked polyubiquitin.	NEDD4L UBE2L3	8.46e-05	9	54	2	25752577
Pubmed	Characterization of human hect domain family members and their interaction with UbcH5 and UbcH7.	NEDD4L UBE2L3	8.46e-05	9	54	2	9575161
Pubmed	The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.	PIK3C2B PIK3R1	1.06e-04	10	54	2	8636073
Pubmed	Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.	PIK3C2B PIK3R1	1.06e-04	10	54	2	8798481
Pubmed	Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.	PIK3C2B PIK3R1	1.06e-04	10	54	2	9247029
Pubmed	HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.	PIK3C2B PIK3R1	1.29e-04	11	54	2	16081599
Pubmed	HIV-1 Tat induces tyrosine phosphorylation of p125FAK and its association with phosphoinositide 3-kinase in PC12 cells.	PIK3C2B PIK3R1	1.29e-04	11	54	2	9708406
Pubmed	Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human.	SYT3 SI	1.29e-04	11	54	2	8617498
Pubmed	HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line.	PIK3C2B PIK3R1	1.29e-04	11	54	2	10985305
Pubmed	Nef-mediated disruption of HLA-A2 transport to the cell surface in T cells.	PIK3C2B PIK3R1	1.29e-04	11	54	2	12584329
Pubmed	Ligands of CD4 inhibit the association of phospholipase Cgamma1 with phosphoinositide 3 kinase in T cells: regulation of this association by the phosphoinositide 3 kinase activity.	PIK3C2B PIK3R1	1.29e-04	11	54	2	9808187
Pubmed	Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer's Disease.	NEDD4L GAR1	1.29e-04	11	54	2	32140098
Pubmed	Genetic mutations associated with cigarette smoking in pancreatic cancer.	MAP2K4 CSF1R PIK3R1	1.32e-04	63	54	3	19351817
Pubmed	Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.	MAP2K4 FARSA THOP1 SPTLC1 FADS2	1.46e-04	323	54	5	24797263
Pubmed	Human immunodeficiency virus type 1 tat-mediated cytotoxicity of human brain microvascular endothelial cells.	PIK3C2B PIK3R1	1.55e-04	12	54	2	14602571
Pubmed	Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.	PIK3C2B PIK3R1	1.55e-04	12	54	2	16514418
Pubmed	HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.	PIK3C2B PIK3R1	1.55e-04	12	54	2	10208934
Pubmed	Recruitment of phosphatidylinositol 3-kinase to CD28 inhibits HIV transcription by a Tat-dependent mechanism.	PIK3C2B PIK3R1	1.55e-04	12	54	2	12077252
Pubmed	Down-regulation of LFA-1-mediated T cell adhesion induced by the HIV envelope glycoprotein gp160 requires phosphatidylinositol-3-kinase activity.	PIK3C2B PIK3R1	1.55e-04	12	54	2	9341793
Pubmed	Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.	PIK3C2B PIK3R1	1.55e-04	12	54	2	12551992
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	FARSA PBRM1 TENT4B GAR1 PNN ATAD5 ECT2	1.67e-04	759	54	7	35915203
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	PBRM1 PNN ATAD5 ASH1L LTBP1 TAF1	1.74e-04	533	54	6	30554943
Pubmed	HIV-1 Nef in macrophage-mediated disease pathogenesis.	PIK3C2B PIK3R1	1.83e-04	13	54	2	23215766
Pubmed	Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells.	PIK3C2B PIK3R1	1.83e-04	13	54	2	9394803
Pubmed	Genomic analysis of synaptotagmin genes.	SYT3 SYTL2	1.83e-04	13	54	2	11543631
Pubmed	Evolution of odorant receptors expressed in mammalian testes.	OR2A7 OR2A4	1.83e-04	13	54	2	11014824
Pubmed	Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.	OR2A7 OR2A4	2.13e-04	14	54	2	7528109
Pubmed	Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line.	PIK3C2B PIK3R1	2.13e-04	14	54	2	17157319
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	PBRM1 ASH1L TAF1	2.21e-04	75	54	3	25593309
Pubmed	HIV Nef enhances Tat-mediated viral transcription through a hnRNP-K-nucleated signaling complex.	PIK3C2B PIK3R1	2.45e-04	15	54	2	18854243
Pubmed	Molecular cloning of murine STAP-1, the stem-cell-specific adaptor protein containing PH and SH2 domains.	CSF1R PIK3R1	2.45e-04	15	54	2	10679268
Pubmed	SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation.	NEDD4L SYT3	2.45e-04	15	54	2	23999003
Pubmed	HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.	PIK3C2B PIK3R1	2.80e-04	16	54	2	16524887
Pubmed	HIV-1 Nef blocks transport of MHC class I molecules to the cell surface via a PI 3-kinase-dependent pathway.	PIK3C2B PIK3R1	2.80e-04	16	54	2	11289809
Pubmed	Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.	PIK3C2B PIK3R1	2.80e-04	16	54	2	20019835
Pubmed	Akt/Nox2/NF-κB signaling pathway is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.	PIK3C2B PIK3R1	2.80e-04	16	54	2	21029719
Pubmed	Erythropoietin plus insulin-like growth factor-I protects against neuronal damage in a murine model of human immunodeficiency virus-associated neurocognitive disorders.	PIK3C2B PIK3R1	2.80e-04	16	54	2	20818790
Pubmed	Comprehensive ubiquitin E2 profiling of ten ubiquitin E3 ligases.	NEDD4L UBE2L3	2.80e-04	16	54	2	23695783
Pubmed	Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation.	CSF1R PIK3R1	2.80e-04	16	54	2	10022833
Pubmed	Functional proteomics mapping of a human signaling pathway.	PBRM1 NEDD4L SYTL2 ASH1L ASCC2 SOX13	3.03e-04	591	54	6	15231748
Pubmed	RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.	NEDD4L UBE2L3	3.17e-04	17	54	2	28292929
Pubmed	Synergistic cooperation between methamphetamine and HIV-1 gsp120 through the P13K/Akt pathway induces IL-6 but not IL-8 expression in astrocytes.	PIK3C2B PIK3R1	3.17e-04	17	54	2	23251686
Pubmed	Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.	PIK3C2B PIK3R1	3.17e-04	17	54	2	12960231
Pubmed	Signaling mechanism of HIV-1 gp120 and virion-induced IL-1beta release in primary human macrophages.	PIK3C2B PIK3R1	3.17e-04	17	54	2	18453587
Pubmed	HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway.	PIK3C2B PIK3R1	3.56e-04	18	54	2	12526811
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	SLC6A11 GABBR2	3.56e-04	18	54	2	18985723
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	TENT4B PNN UBE2L3 ECT2 CWF19L1	3.91e-04	400	54	5	35013556
Pubmed	Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.	PIK3C2B PIK3R1	3.98e-04	19	54	2	31959764
Pubmed	HIV-1 Tat protein induces the production of IDO in human monocyte derived-dendritic cells through a direct mechanism: effect on T cells proliferation.	PIK3C2B PIK3R1	3.98e-04	19	54	2	24073214
Pubmed	SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.	NEDD4L UBE2L3	3.98e-04	19	54	2	21572392
Pubmed	Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.	PIK3C2B PIK3R1	4.88e-04	21	54	2	9446795
Pubmed	HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells.	PIK3C2B PIK3R1	5.36e-04	22	54	2	11994280
Pubmed	HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.	PIK3C2B PIK3R1	5.36e-04	22	54	2	11154208
Pubmed	EG-1 interacts with c-Src and activates its signaling pathway.	NEDD4L PIK3R1	5.36e-04	22	54	2	16964398
Pubmed	The E3 ubiquitin ligase UBR5 interacts with the H/ACA ribonucleoprotein complex and regulates ribosomal RNA biogenesis in embryonic stem cells.	GAR1 TAF1 RPL35	5.77e-04	104	54	3	31365120
Pubmed	Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.	ZBTB38 PRKG2	5.86e-04	23	54	2	19343178
Pubmed	HIV-1 Tat promotes Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6-induced angiogenesis and tumorigenesis by regulating PI3K/PTEN/AKT/GSK-3β signaling pathway.	PIK3C2B PIK3R1	5.86e-04	23	54	2	23301033
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	FARSA SAMD9 TENT4B GAR1 PNN ASCC2 RPL35 ECT2	6.76e-04	1257	54	8	36526897
Pubmed	Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.	PIK3C2B PIK3R1	6.94e-04	25	54	2	15689238
Pubmed	Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy.	PIK3C2B PIK3R1	6.94e-04	25	54	2	17632570
Pubmed	Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.	ACSM2A ACSM2B	6.94e-04	25	54	2	19372376
Pubmed	System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.	NEDD4L UBE2L3	7.51e-04	26	54	2	26949039
Pubmed	Identification of 15 loci influencing height in a Korean population.	ZBTB38 LTBP1	8.10e-04	27	54	2	19893584
Pubmed	HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.	PIK3C2B PIK3R1	8.10e-04	27	54	2	11156964
Pubmed	Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.	ELOVL4 SPTLC1	8.10e-04	27	54	2	25269881
Cytoband	7q21.2	SAMD9 LRRD1	1.41e-04	15	54	2	7q21.2
Cytoband	16p12.3	ACSM2A ACSM2B	7.44e-04	34	54	2	16p12.3
Cytoband	1q32	PIK3C2B SOX13	1.54e-03	49	54	2	1q32
Cytoband	1q22	ASH1L DCST1	2.08e-03	57	54	2	1q22
GeneFamily	Acyl-CoA synthetase family	ACSM2A ACSM2B	1.22e-03	26	36	2	40
GeneFamily	Ubiquitin conjugating enzymes E2	UBE2L3 UBE2L5	3.01e-03	41	36	2	102
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	DPYS ZBTB38 NEDD4L ASH1L ACSM2A ACSM2B	5.54e-06	221	53	6	M39222
Coexpression	MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP	PNN UBE2L3 PIK3R1 ENPP2 ZNF335 LTBP1 FASTKD3	1.75e-05	408	53	7	M11891
Coexpression	MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP	PNN UBE2L3 PIK3R1 ENPP2 ZNF335 LTBP1 FASTKD3	1.95e-05	415	53	7	MM1028
Coexpression	GSE17721_CTRL_VS_CPG_24H_BMDC_UP	ELOVL4 ASH1L ASCC2 DEPDC1 ACSM2A	5.24e-05	200	53	5	M3771
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	SYTL2 FADS2 DEPDC1 PRKG2 ECT2	3.77e-06	194	54	5	c093c5e161b97ad770bfbaad3023eba4537101b5
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS RPL35 STEAP1B ACSM2A ACSM2B	4.27e-06	199	54	5	f38e7bc3dc0e7822bee2df5634bf47a5c7145d60
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 CARF AGTR1 IQUB	5.13e-05	168	54	4	1bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 CARF AGTR1 IQUB	5.13e-05	168	54	4	c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB38 SAMD9 PIK3R1 SYTL2	5.13e-05	168	54	4	b94b1f37c92e019d01ecfa3b7cc6797b6e4a56ff
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 CARF AGTR1 IQUB	5.13e-05	168	54	4	69f534de0f9a293047bea03cb1b78551087a8df5
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 CARF AGTR1 IQUB	5.13e-05	168	54	4	83b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAP2K4 THOP1 PBRM1 FADS2	5.37e-05	170	54	4	0f215911b5880eeffeb43230f7eeaf55b612eaf2
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYS CSF1R GAR1 LTBP1	5.37e-05	170	54	4	8d3c51364a332020810836e2055c60893c10d7f3
ToppCell	URO-Lymphocyte-B-Plasmablast\|URO / Disease, Lineage and Cell Type	IGKV1-8 DEPDC1 TTC39A ECT2	5.62e-05	172	54	4	48888ef50ac784b38aca81da68f8a94ce09c670d
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	DPYS SYTL2 ACSM2A ACSM2B	6.14e-05	176	54	4	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ELOVL4 SAMD9 PIK3R1 SYTL2	6.14e-05	176	54	4	003076f1a983409ddf31b9c19e61c1facdd72566
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYS CSF1R GAR1 LTBP1	6.28e-05	177	54	4	4a697866ed542d3201714234cee03451adf1dcc9
ToppCell	C_00\|World / shred on cell type and cluster	ZBTB38 PNN ATAD5 PIK3R1	6.56e-05	179	54	4	da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ELOVL4 PIK3R1 SYTL2 DCST1	6.70e-05	180	54	4	e53e9f3ebd48fb8237515e740ba5d9880ed6ade3
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-T_mait-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ELOVL4 PIK3R1 SYTL2 DCST1	6.70e-05	180	54	4	9d18aa1044945fe6481ea3284037a777657fd837
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAR1 SYTL2 SULT6B1 RPL35	7.45e-05	185	54	4	5414a66169c39d09a67b1050aad5e61f46b3749a
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST3GAL6 SPTLC1 FADS2 TTC39A	7.45e-05	185	54	4	e29079ef09aee62c3e9756341db4e59ca9dbf7ac
ToppCell	facs-Large_Intestine-Distal-24m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST3GAL6 SPTLC1 FADS2 TTC39A	7.45e-05	185	54	4	2ecc4b76b3645b65c226c2298bff307cc6479172
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS NEDD4L ACSM2A ACSM2B	7.61e-05	186	54	4	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	mild_COVID-19-CD4+_CTL\|mild_COVID-19 / disease group, cell group and cell class (v2)	ZBTB38 PIK3R1 SYTL2 SOX13	7.77e-05	187	54	4	49196d07e4716c87d33229a4569bdb6b4613b3eb
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	DPYS ENPP2 ACSM2A ACSM2B	7.77e-05	187	54	4	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	facs-Large_Intestine-Distal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST3GAL6 SYTL2 FADS2 TTC39A	8.26e-05	190	54	4	3964a8390522b61b73235151bb0a2ff36b856867
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS NEDD4L ACSM2A ACSM2B	8.43e-05	191	54	4	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS NEDD4L ACSM2A ACSM2B	8.43e-05	191	54	4	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 ENPP2 SYTL2 LTBP1	8.43e-05	191	54	4	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte\|World / Lineage, cell class and subclass	AGTR1 FADS2 DEPDC1 LTBP1	8.78e-05	193	54	4	352cd442b6e62f09b6d22a139774067873644594
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ELOVL4 ZBTB38 PIK3R1 SYTL2	8.95e-05	194	54	4	b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCell	healthy_donor-Lymphocytic-T_cell-Gamma_Delta_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ELOVL4 PIK3R1 SYTL2 RPL35	9.32e-05	196	54	4	6eabbac1625f715531bae562a28da27664572600
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 NEDD4L SYTL2 RPL35	9.50e-05	197	54	4	e5ab45cfe4ebd02ca25029d87bece70dfbb4adc4
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_cytokine_secreting_effector_T_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZBTB38 PNN PIK3R1 SYTL2	9.69e-05	198	54	4	34c564ece9a2b94dcf646e3c95b5be9c5ecfaafe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS DEPDC1 ACSM2A ACSM2B	9.69e-05	198	54	4	7db113a6e7962ff26c1e1a43baa1a4230cf5f393
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PNN PIK3R1 SYTL2 ASH1L	9.88e-05	199	54	4	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	VE-cycling\|VE / Condition, Cell_class and T cell subcluster	ATAD5 FADS2 DEPDC1 ECT2	9.88e-05	199	54	4	47c47ebc318a0b98841ca2656837bbd068899559
ToppCell	VE-cycling-\|VE / Condition, Cell_class and T cell subcluster	ATAD5 FADS2 DEPDC1 ECT2	9.88e-05	199	54	4	c0a67149a19b65b3069dbc5261d81f658e6e39a2
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	SAMD9 PIK3R1 SYTL2 ASH1L	9.88e-05	199	54	4	952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATAD5 DEPDC1 ECT2 SOX13	9.88e-05	199	54	4	c7c501ad144ac5488d0b0496554d46616f2e01a6
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Artery\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	PIK3C2B ENPP2 LTBP1 SOX13	1.01e-04	200	54	4	34b279804475ea58fbb052b96f44128c082627a9
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 SAMD9 PIK3R1 SYTL2	1.01e-04	200	54	4	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PIK3C2B ENPP2 LTBP1 SOX13	1.01e-04	200	54	4	8552cc7a439449b30b59760c3e8667217b9852b5
ToppCell	severe-CD8+_Tem\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 PIK3R1 SYTL2 RPL35	1.01e-04	200	54	4	aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SAMD9 PNN PIK3R1 ASH1L	1.01e-04	200	54	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZBTB38 SAMD9 PIK3R1 SYTL2	1.01e-04	200	54	4	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIK3C2B ENPP2 LTBP1 SOX13	1.01e-04	200	54	4	45c08f1befe78553bbadcc2fcffb6138306638f3
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC6A11 SULT6B1 FADS2	3.31e-04	111	54	3	7d7aad8e9811c67fb9abfb4ebc75def01a517adf
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	SLC6A11 SULT6B1 FADS2	3.31e-04	111	54	3	cb45322fbeafec2f1ab7a3727da69abb1047567d
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B DEPDC1 TTC39A	4.68e-04	125	54	3	35042ed43045dddc341b76cc5f9fe31b5ba0abb8
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B DEPDC1 TTC39A	4.79e-04	126	54	3	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3C2B DEPDC1 TTC39A	5.37e-04	131	54	3	419a0a83b38eaea890d065c3f252ef83c2d37b5b
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ELOVL4 ENPP2 DCST1	7.65e-04	148	54	3	5729826e8d45bf995e2efa6707c49e264d12d112
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AGTR1 SULT6B1 SOX13	8.11e-04	151	54	3	ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DEPDC1 ACSM2A ACSM2B	8.42e-04	153	54	3	499670e716fc85ce76630fc813cec86f8419f2a1
ToppCell	facs-BAT-Fat-24m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3R1 SYTL2 ASCC2	8.74e-04	155	54	3	550e7e7e52829244ead829e5be010bfdc71e2ba5
ToppCell	facs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATAD5 DEPDC1 ECT2	9.07e-04	157	54	3	0fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCell	10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	ATAD5 UBE2L5 ECT2	9.07e-04	157	54	3	d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCell	Bac-SEP-Lymphocyte-T_NK-MAIT\|Bac-SEP / Disease, Lineage and Cell Type	ELOVL4 PIK3R1 SYTL2	9.41e-04	159	54	3	e043c65f3febdfa7f75a67702e92fcdebe144a00
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 PIK3R1 CARF	9.76e-04	161	54	3	2fe77af3b41e6eacb707a64feea18f9991618173
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF1R AGTR1 DEPDC1	9.93e-04	162	54	3	b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCell	droplet-Bladder-nan-3m-Hematologic-macrophage\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYS CSF1R ST3GAL6	9.93e-04	162	54	3	0cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCell	facs-Marrow-Granulocytes-24m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYS CSF1R LTBP1	9.93e-04	162	54	3	2787be283b7a705647058aeb9bc54006ce5ffe95
ToppCell	LPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THOP1 GABBR2 SOX13	1.01e-03	163	54	3	6b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCell	droplet-Spleen-nan-3m-Lymphocytic-NK_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3R1 SYTL2 DCST1	1.01e-03	163	54	3	2e1c1193c04620cc187b1567dfba025beef1e4e1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ELOVL4 SYTL2 PRKG2	1.05e-03	165	54	3	5e7ee76f3dcddbd1b560bacd043f9001b0c18b5f
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASCC2 DEPDC1 TTC39A	1.05e-03	165	54	3	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AGTR1 LTBP1 DCST1	1.05e-03	165	54	3	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	AGTR1 LTBP1 DCST1	1.05e-03	165	54	3	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASCC2 DEPDC1 TTC39A	1.05e-03	165	54	3	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATAD5 ENPP2 ECT2	1.08e-03	167	54	3	9280558baddea51aae47f3383d895a9b0c6749a4
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CSF1R PIK3C2B IQUB	1.08e-03	167	54	3	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT3 ATAD5 ECT2	1.08e-03	167	54	3	f5bffa77061baec0ba87bd688a047595f32534db
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS ACSM2A ACSM2B	1.10e-03	168	54	3	fa0d251693935116adf633d02b7ec4a295100865
ToppCell	Control-Epithelial_alveolar-Mes-like\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FARSA FADS2 ECT2	1.10e-03	168	54	3	3c2ce9cfaca8ceab9b29f918ab46afc69eba3330
ToppCell	severe_influenza-CD4+_CTL\|severe_influenza / disease group, cell group and cell class (v2)	ZBTB38 PIK3R1 SYTL2	1.10e-03	168	54	3	50697fda702a09d9a621e9f79c2b52d53792dd2a
ToppCell	Control-Epithelial_alveolar-Mes-like-AT1_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FARSA FADS2 ECT2	1.10e-03	168	54	3	49180994311b3f4f9ec338b1d35d8edd7422e3c9
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	DEPDC1 PRKG2 ECT2	1.12e-03	169	54	3	a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	SLC6A11 SOX13 CWF19L1	1.12e-03	169	54	3	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 DEPDC1 ECT2	1.12e-03	169	54	3	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 DEPDC1 ECT2	1.12e-03	169	54	3	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYT3 FADS2 LTBP1	1.12e-03	169	54	3	2456b3e7776e8a2214972be1b4d66a3ca5480ae0
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATAD5 DEPDC1 ECT2	1.12e-03	169	54	3	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	DEPDC1 PRKG2 ECT2	1.12e-03	169	54	3	195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCell	facs-Marrow-T_cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARF SYTL2 FADS2	1.12e-03	169	54	3	2a35846b0e0be0a19a5a04a86cbd72ce65257c8a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NEDD4L SYTL2 IQUB	1.14e-03	170	54	3	928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 DCST1 SOX13	1.14e-03	170	54	3	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT3 SULT6B1 FADS2	1.14e-03	170	54	3	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 DCST1 SOX13	1.14e-03	170	54	3	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELOVL4 DCST1 SOX13	1.14e-03	170	54	3	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS ACSM2A ACSM2B	1.16e-03	171	54	3	f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC66 ECT2 ACSM2B	1.16e-03	171	54	3	1eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CSF1R DEPDC1 ECT2	1.16e-03	171	54	3	41932c9e70829ee3d55ca5fdb74d290fc8229416
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PIK3C2B ENPP2 SOX13	1.16e-03	171	54	3	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-MAIT\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ELOVL4 PIK3R1 SYTL2	1.18e-03	172	54	3	18bda0038cb37da6784e7bf7291272c108cfd9c5
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATAD5 DEPDC1 ECT2	1.18e-03	172	54	3	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYTL2 DEPDC1 ECT2	1.18e-03	172	54	3	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DPYS ACSM2A ACSM2B	1.20e-03	173	54	3	8888434641ea554a9b62c436e87920378eef29cd
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AGTR1 SYTL2 LTBP1	1.20e-03	173	54	3	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 DEPDC1 ECT2	1.22e-03	174	54	3	84da9faff088d05233183b425385beb054c92d1b
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-CD4_TEM\|Multiple_Sclerosis / Disease, Lineage and Cell Type	ELOVL4 PIK3R1 RPL35	1.22e-03	174	54	3	d2ea5b55bf03a8013816d073896208f311c3e544
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYT3 DEPDC1 ECT2	1.22e-03	174	54	3	dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATAD5 DEPDC1 TTC39A	1.24e-03	175	54	3	a6913f992a1ea20b43e5adeca3ede3a6fda820ad
Drug	Caffeic acid [3331-39-5]; Down 200; 22.2uM; PC3; HT_HG-U133A	ST3GAL6 ATAD5 SYTL2 SPTLC1 TAF1 CWF19L1	5.05e-06	193	52	6	6753_DN
Drug	wortmannin from Penicillium funiculosum; Down 200; 0.01uM; MCF7; HT_HG-U133A	ELOVL4 FARSA SPTLC1 ASH1L LTBP1 CWF19L1	5.36e-06	195	52	6	1668_DN
Drug	minocycline; Down 200; 10.5uM; MCF7; HT_HG-U133A_EA	ZBTB38 THOP1 PBRM1 ZNF335 LTBP1 SOX13	5.85e-06	198	52	6	1135_DN
Drug	Bethanechol chloride [590-63-6]; Up 200; 20.4uM; MCF7; HT_HG-U133A	CSF1R ST3GAL6 ATAD5 FADS2 GABBR2 SLC23A2	5.85e-06	198	52	6	3537_UP
Drug	rapamycin, Streptomyces hygroscepicus; Down 200; 0.1uM; MCF7; HT_HG-U133A	FARSA CSF1R SPTLC1 FADS2 TTC39A CWF19L1	6.20e-06	200	52	6	5927_DN
Drug	AC1NUTWC	ACSM2A ACSM2B	3.06e-05	4	52	2	CID005460914
Drug	A-25	DPYS PNN SI	3.54e-05	28	52	3	CID003026721
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	ELOVL4 NEDD4L ENPP2 AGTR1 SYTL2	4.91e-05	175	52	5	3746_UP
Drug	Alpha-Linolenic Acid	ELOVL4 FADS2	5.09e-05	5	52	2	DB00132
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; PC3; HT_HG-U133A	ELOVL4 NEDD4L ENPP2 AGTR1 SLC23A2	5.62e-05	180	52	5	5950_UP
Drug	AG-1478; Down 200; 31.6uM; MCF7; HT_HG-U133A_EA	NEDD4L PNN ATAD5 PIK3R1 ZNF335	6.73e-05	187	52	5	1141_DN
Drug	thioridazine hydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A_EA	PNN UBE2L3 ATAD5 PIK3R1 FASTKD3	7.63e-05	192	52	5	1068_DN
Drug	AG-012559 [369370-06-9]; Up 200; 10uM; PC3; HT_HG-U133A	ZBTB38 PNN PIK3R1 LTBP1 SLC23A2	7.82e-05	193	52	5	6920_UP
Drug	Glycocholic acid [475-31-0]; Down 200; 8.6uM; PC3; HT_HG-U133A	FARSA ATAD5 SPTLC1 TAF1 CWF19L1	7.82e-05	193	52	5	6716_DN
Drug	Thiamphenicol [15318-45-3]; Down 200; 11.2uM; MCF7; HT_HG-U133A	NEDD4L ATAD5 TAF1 SOX13 CWF19L1	7.82e-05	193	52	5	7033_DN
Drug	Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A	ZBTB38 PIK3R1 LTBP1 TAF1 SLC23A2	8.01e-05	194	52	5	4361_DN
Drug	Amikacin hydrate [37517-28-5]; Down 200; 6.6uM; PC3; HT_HG-U133A	FARSA SYTL2 SPTLC1 SLC23A2 CWF19L1	8.01e-05	194	52	5	6715_DN
Drug	AC1L1I1D	CSF1R ENPP2 SI	8.26e-05	37	52	3	CID000004381
Drug	PNU-0251126 [267429-19-6]; Up 200; 1uM; MCF7; HT_HG-U133A	ELOVL4 NEDD4L TAF1 GABBR2 SLC23A2	8.41e-05	196	52	5	4714_UP
Drug	Dihydroergocristine mesylate [24730-10-7]; Down 200; 5.6uM; MCF7; HT_HG-U133A	ELOVL4 NEDD4L ATAD5 LTBP1 TAF1	8.82e-05	198	52	5	7034_DN
Drug	Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; PC3; HT_HG-U133A	SAMD9 CSF1R ENPP2 GABBR2 SOX13	8.82e-05	198	52	5	5867_UP
Drug	Nalbuphine hydrochloride [23277-43-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A	THOP1 NEDD4L ATAD5 ZNF335 SOX13	8.82e-05	198	52	5	7177_DN
Drug	Pentylenetetrazole [54-95-5]; Up 200; 29uM; PC3; HT_HG-U133A	CSF1R ASH1L TTC39A GABBR2 SOX13	9.03e-05	199	52	5	2092_UP
Drug	Ozagrel hydrochloride [78712-43-3]; Down 200; 15.2uM; PC3; HT_HG-U133A	ST3GAL6 ZNF335 SYTL2 SPTLC1 TAF1	9.03e-05	199	52	5	7281_DN
Drug	somatoprim	SLC6A11 GABBR2	1.07e-04	7	52	2	CID000001695
Drug	pyrophosphate	DPYS FARSA PIK3R1 ENPP2 FADS2 TAF1 ACSM2A ACSM2B	1.09e-04	654	52	8	CID000001023
Disease	BMI-adjusted waist circumference, physical activity measurement	ZBTB38 PBRM1 ATAD5 LTBP1 PRKG2	2.58e-06	123	52	5	EFO_0007789, EFO_0008002
Disease	X-21319 measurement	ACSM2A ACSM2B	3.05e-06	2	52	2	EFO_0800807
Disease	X-11478 measurement	ACSM2A ACSM2B	9.13e-06	3	52	2	EFO_0021242
Disease	Adenocarcinoma of large intestine	MAP2K4 PIK3R1 TAF1 PRKG2	2.53e-05	96	52	4	C1319315
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	3.04e-05	5	52	2	EFO_0800378
Disease	macrophage colony-stimulating factor 1 receptor measurement	CSF1R ST3GAL6	4.55e-05	6	52	2	EFO_0020547
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	4.55e-05	6	52	2	EFO_0800106
Disease	sexual dimorphism measurement	ZBTB38 CCDC66 ATAD5 PIK3R1 ZNF335 FADS2 LTBP1 PRKG2 DCST1	1.22e-04	1106	52	9	EFO_0021796
Disease	lymphocyte percentage of leukocytes	ZBTB38 TENT4B CSF1R UBE2L3 FADS2 TTC39A STEAP1B	1.59e-04	665	52	7	EFO_0007993
Disease	central corneal thickness	ZBTB38 SAMD9 ST3GAL6 LTBP1 UBE2L5	2.12e-04	309	52	5	EFO_0005213
Disease	non-high density lipoprotein cholesterol measurement	THOP1 PBRM1 CSF1R UBE2L3 FADS2 UBE2L5 CWF19L1	2.43e-04	713	52	7	EFO_0005689
Disease	non-alcoholic fatty liver disease	NEDD4L ACSM2A CWF19L1 ACSM2B	3.01e-04	182	52	4	EFO_0003095
Disease	nasopharynx carcinoma (is_implicated_in)	MAP2K4 CSF1R	3.15e-04	15	52	2	DOID:9261 (is_implicated_in)
Disease	phosphatidylcholine 38:6 measurement	FADS2 LTBP1	3.60e-04	16	52	2	EFO_0010388
Disease	vitamin C measurement	FADS2 SLC23A2	3.60e-04	16	52	2	EFO_0600003
Disease	birth weight, parental genotype effect measurement	ZBTB38 PIK3R1 ENPP2 STEAP1B	3.68e-04	192	52	4	EFO_0004344, EFO_0005939
Disease	forced expiratory volume	ZBTB38 PBRM1 TENT4B PIK3C2B ATAD5 ENPP2 ASCC2	4.47e-04	789	52	7	EFO_0004314
Disease	lean body mass	ZBTB38 ATAD5 PIK3R1 LTBP1 PRKG2	5.39e-04	379	52	5	EFO_0004995
Disease	Neoplasm Metastasis	CSF1R PIK3C2B ENPP2 AGTR1	5.84e-04	217	52	4	C0027627
Disease	birth weight	TENT4B ATAD5 PIK3R1 ENPP2 STEAP1B	6.80e-04	399	52	5	EFO_0004344
Disease	prostate carcinoma in situ (is_marker_for)	MAP2K4 CSF1R	1.12e-03	28	52	2	DOID:8634 (is_marker_for)
Disease	lung small cell carcinoma (is_implicated_in)	PBRM1 PIK3R1	1.12e-03	28	52	2	DOID:5409 (is_implicated_in)
Disease	Epileptic encephalopathy	NEDD4L GABBR2	1.28e-03	30	52	2	C0543888
Disease	smoking behavior, BMI-adjusted waist circumference	ZBTB38 LTBP1 PRKG2	1.31e-03	122	52	3	EFO_0004318, EFO_0007789
Disease	serum IgA measurement	ASCC2 FADS2	1.37e-03	31	52	2	EFO_0004912
Disease	aortic stenosis	FADS2 STEAP1B	1.37e-03	31	52	2	EFO_0000266
Disease	triacylglycerol 54:3 measurement	FADS2 GABBR2	1.37e-03	31	52	2	EFO_0010421
Disease	Squamous cell carcinoma of lung	MAP2K4 CSF1R	1.46e-03	32	52	2	C0149782
Disease	renal cell carcinoma (is_marker_for)	CSF1R PIK3R1 AGTR1	1.51e-03	128	52	3	DOID:4450 (is_marker_for)
Disease	phosphatidylcholine 38:2 measurement	ZBTB38 FADS2	1.75e-03	35	52	2	EFO_0010384

Protein segments in the cluster

Peptide	Gene	Start	Entry
PEFSLKKYFPLLLKK	ATAD5	956	Q96QE3
YKKPDVPLYKKIRSN	ASH1L	2066	Q9NR48
RYFLQLLKYIPPKAK	AGTR1	311	P30556
APYKYPRKIEFVLNL	ACSM2A	536	Q08AH3
QKADRYFVLYKPPPK	ASCC2	31	Q9H1I8
PKYKELLKHPFILMY	MAP2K4	356	P45985
FLKYSKDLVKTYPPF	ECT2	536	Q9H8V3
LIKDFTKKYPVLPYL	TENT4B	246	Q8NDF8
PIEYGKKKLKYLPYN	FADS2	246	O95864
LPSKKKYPDYYQQIK	PBRM1	411	Q86U86
FPKDILKIKYVKYLY	LRRD1	156	A4D1F6
LFLNFYIRTYKEPKK	ELOVL4	261	Q9GZR5
KFIPRKPFAEYIYKR	DPYS	461	Q14117
PARIYIKKVQKFPEY	CARF	316	Q8N187
NPEKKKYLYAFSIVP	CWF19L1	231	Q69YN2
KYIRTKTKPHLFYIP	PNN	231	Q9H307
EYVLKPKYFPAQKGI	LTBP1	306	Q14766
RKKLKQFQKEYPLIY	DEPDC1	761	Q5TB30
PRYGNPKEQKKYLLL	OR2A7	261	Q96R45
YNPKLDVKLLYPVSK	PIK3R1	416	P27986
PFIVKLYRTFKDNKY	PRKG2	511	Q13237
PRYGNPKEQKKYLLL	OR2A4	261	O95047
YVKIYLLPDPQKTTK	PIK3C2B	1541	O00750
YPGILVNSKFYKLVK	CSF1R	856	P07333
FYFPKREKKRILFLY	DCST1	581	Q5T197
RYIPASEKYPKQLQK	CCDC66	711	A2RUB6
VAKYLKVPQDPLKFY	IQUB	581	Q8NA54
KVPQDPLKFYKKIYF	IQUB	586	Q8NA54
PVLADKKKYPYFFRT	GABBR2	161	O75899
YQQKPGKAPKLLIYA	IGKV1-8	56	A0A0C4DH67
KYKTKVPPFENIELY	ENPP2	496	Q13822
LQKFYIDPYKLLPLQ	GAR1	141	Q9NY12
DPYVKIYLLPDRKKK	SYT3	336	Q9BQG1
KKQRSDPYVKAYLLP	SYTL2	661	Q9HCH5
AVSKKKYKYPEFPVL	SULT6B1	81	Q6IMI4
KFYKGKKYKPLDLRP	RPL35	71	P42766
LYRLAQKKPFTPVKY	FARSA	336	Q9Y285
KNYIPYLTKLKFSLK	SAMD9	1251	Q5K651
PVNKKFVPDYYKVIV	TAF1	1531	P21675
FYKGPKLLPKYQVKS	FASTKD3	506	Q14CZ7
FWKKPALNLIYKPYQ	ST3GAL6	211	Q9Y274
QFKIYDPQKKRYEVP	SI	1031	P14410
PLPELVKLKYKYKAR	SPTLC1	256	O15269
YFYKIPILVINKVLP	STEAP1B	86	Q6NZ63
APYKYPRKIEFVLNL	ACSM2B	536	Q68CK6
EKYPDYKYKPRPKRT	SOX13	486	Q9UN79
YARNVKFPLPIYKSK	SLC23A2	286	Q9UGH3
YPFKPPRITFKTKIY	UBE2L5	61	A0A1B0GUS4
GIFIFFLIKYKPLKY	SLC6A11	526	P48066
YPYKLYRLLPMKCKR	ZBTB38	561	Q8NAP3
KVTLKYPHYFPLLKK	THOP1	216	P52888
RKYYYKSPKPLLRPF	ZNF335	451	Q9H4Z2
EKLLKPYLNRYPKGA	TTC39A	301	Q5SRH9
YPFKPPKITFKTKIY	UBE2L3	61	P68036
YDYFRKKLKKPADIP	NEDD4L	601	Q96PU5