Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL5A1 COL18A1 COL11A1 COL11A2

1.91e-0646394GO:0030020
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C3 AKR1C4

2.22e-054392GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C3 AKR1C4

2.22e-054392GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C3 AKR1C4

2.22e-054392GO:0047743
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL5A1 NID2 COL18A1 COL11A1 COL11A2

3.11e-05188395GO:0005201
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C3 AKR1C4

3.70e-055392GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C3 AKR1C4

3.70e-055392GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C3 AKR1C4

3.70e-055392GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C3 AKR1C4

3.70e-055392GO:0047006
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C3 AKR1C4

3.70e-055392GO:0047787
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C3 AKR1C4

3.70e-055392GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C3 AKR1C4

3.70e-055392GO:0047086
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C3 AKR1C4

5.55e-056392GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C3 AKR1C4

7.76e-057392GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C3 AKR1C4

1.03e-048392GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C3 AKR1C4

1.03e-048392GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C3 AKR1C4

1.03e-048392GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C3 AKR1C4

1.33e-049392GO:0047044
GeneOntologyMolecularFunctiontestosterone dehydrogenase (NAD+) activity

AKR1C3 AKR1C4

1.33e-049392GO:0047035
GeneOntologyMolecularFunctionNADP+ binding

AKR1C3 AKR1C4

1.33e-049392GO:0070401
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C3 AKR1C4

1.66e-0410392GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C3 AKR1C4

1.66e-0410392GO:0032052
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4

2.02e-0411392GO:0030283
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C3 AKR1C4

3.33e-0414392GO:0001758
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C3 AKR1C4

3.33e-0414392GO:0004032
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4

6.91e-0420392GO:0004303
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C3 AKR1C4

9.98e-0424392GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C3 AKR1C4

1.17e-0326392GO:0004022
GeneOntologyMolecularFunctionNADPH binding

AKR1C3 AKR1C4

1.17e-0326392GO:0070402
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C3 AKR1C4

1.27e-0327392GO:0008106
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C3 AKR1C4

1.56e-0330392GO:0018455
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C3 AKR1C4

1.78e-0332392GO:0004033
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4

1.89e-0333392GO:0033764
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4

2.00e-0334392GO:0016628
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C3 AKR1C4

2.63e-0339392GO:0016229
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C3 AKR1C4

2.77e-0340392GO:0016709
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

PSMC4 CHD3 GNAS RTEL1 KIFC2 RAB43

3.66e-03775396GO:0017111
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C3 AKR1C4

3.96e-0348392GO:0016620
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C3 AKR1C4

5.36e-0356392GO:0016903
GeneOntologyMolecularFunctionpyrophosphatase activity

PSMC4 CHD3 GNAS RTEL1 KIFC2 RAB43

5.39e-03839396GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PSMC4 CHD3 GNAS RTEL1 KIFC2 RAB43

5.42e-03840396GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PSMC4 CHD3 GNAS RTEL1 KIFC2 RAB43

5.42e-03840396GO:0016818
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C3 AKR1C4

6.13e-0360392GO:0016655
GeneOntologyMolecularFunctionheparin binding

COL5A1 COL11A1 COL11A2

6.20e-03192393GO:0008201
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C3 AKR1C4

6.53e-0362392GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C3 AKR1C4

6.53e-0362392GO:0050661
GeneOntologyMolecularFunctionstructural molecule activity

COL5A1 NID2 COL18A1 COL11A1 COL11A2 NPHP4

7.18e-03891396GO:0005198
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

AKR1C4 SLC16A1

8.26e-0370392GO:1901618
GeneOntologyMolecularFunctionATP hydrolysis activity

PSMC4 CHD3 RTEL1 KIFC2

1.05e-02441394GO:0016887
GeneOntologyMolecularFunctioncarboxylic acid binding

AKR1C3 COL11A1 AKR1C4

1.13e-02239393GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

AKR1C3 COL11A1 AKR1C4

1.33e-02254393GO:0043177
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

AKR1C4 SLC16A1

1.34e-0290392GO:0008028
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C3 AKR1C4 GNAS

1.08e-0523393GO:0071379
GeneOntologyBiologicalProcesscollagen fibril organization

COL5A1 COL18A1 COL11A1 COL11A2

1.27e-0576394GO:0030199
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C3 AKR1C4

2.09e-054392GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C3 AKR1C4

2.09e-054392GO:0006709
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C3 AKR1C4

2.09e-054392GO:0071395
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C3 AKR1C4

2.09e-054392GO:0008208
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C3 COL18A1 AKR1C4

2.98e-0532393GO:2000353
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C3 AKR1C4

3.47e-055392GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C3 AKR1C4

3.47e-055392GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C3 AKR1C4

3.47e-055392GO:0045827
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C3 AKR1C4

3.47e-055392GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C3 AKR1C4

3.47e-055392GO:0120256
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C3 AKR1C4

3.47e-055392GO:1900053
GeneOntologyBiologicalProcessresponse to prostaglandin

AKR1C3 AKR1C4 GNAS

4.27e-0536393GO:0034694
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C3 AKR1C4

5.20e-056392GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C3 AKR1C4

5.20e-056392GO:0016095
GeneOntologyBiologicalProcessendocardium morphogenesis

SOX17 RBPJ

7.27e-057392GO:0003160
GeneOntologyBiologicalProcesstendon development

COL5A1 COL11A1

7.27e-057392GO:0035989
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C3 AKR1C4

7.27e-057392GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C3 AKR1C4

7.27e-057392GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C3 AKR1C4

7.27e-057392GO:1900052
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C3 AKR1C4

1.24e-049392GO:0044597
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C3 AKR1C4

1.55e-0410392GO:0044598
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C3 AKR1C4

1.55e-0410392GO:0019747
GeneOntologyBiologicalProcessregulation of endodermal cell differentiation

SOX17 COL5A1

1.55e-0410392GO:1903224
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C3 AKR1C4

1.55e-0410392GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C3 AKR1C4

1.55e-0410392GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C3 AKR1C4

1.55e-0410392GO:0030647
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C3 AKR1C4

1.90e-0411392GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C3 AKR1C4

1.90e-0411392GO:0016115
GeneOntologyBiologicalProcesspositive regulation of epithelial cell apoptotic process

AKR1C3 COL18A1 AKR1C4

1.99e-0460393GO:1904037
GeneOntologyBiologicalProcessendocardium development

SOX17 RBPJ

2.68e-0413392GO:0003157
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C3 AKR1C4

3.12e-0414392GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C3 AKR1C4

3.12e-0414392GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C3 AKR1C4

3.60e-0415392GO:0016102
GeneOntologyBiologicalProcessregulation of endothelial cell apoptotic process

AKR1C3 COL18A1 AKR1C4

3.69e-0474393GO:2000351
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C3 AKR1C4

4.11e-0416392GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C3 AKR1C4

4.11e-0416392GO:0032351
GeneOntologyBiologicalProcessconnective tissue development

COL5A1 ZBTB7A COL11A1 COL11A2 GNAS

4.47e-04343395GO:0061448
GeneOntologyBiologicalProcessendothelial cell apoptotic process

AKR1C3 COL18A1 AKR1C4

4.47e-0479393GO:0072577
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C3 AKR1C4

5.23e-0418392GO:0030656
GeneOntologyBiologicalProcesscellular response to calcium ion

AKR1C3 AKR1C4 NLGN1

6.14e-0488393GO:0071277
GeneOntologyBiologicalProcessendoderm development

SOX17 ANKRD17 COL5A1

6.14e-0488393GO:0007492
GeneOntologyBiologicalProcessextracellular matrix organization

COL5A1 NID2 COL18A1 COL11A1 COL11A2

6.86e-04377395GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

COL5A1 NID2 COL18A1 COL11A1 COL11A2

6.94e-04378395GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

COL5A1 NID2 COL18A1 COL11A1 COL11A2

7.03e-04379395GO:0045229
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C3 AKR1C4

7.15e-0421392GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C3 AKR1C4

7.15e-0421392GO:0016114
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C3 AKR1C4

7.15e-0421392GO:0048385
GeneOntologyBiologicalProcessretinal metabolic process

AKR1C3 AKR1C4

7.15e-0421392GO:0042574
GeneOntologyBiologicalProcessketone catabolic process

AKR1C3 AKR1C4

7.15e-0421392GO:0042182
GeneOntologyBiologicalProcesspostsynapse assembly

C1QL2 NLGN1 NUMBL

7.21e-0493393GO:0099068
GeneOntologyBiologicalProcessparturition

AKR1C3 AKR1C4

7.86e-0422392GO:0007567
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C3 AKR1C4

7.86e-0422392GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C3 AKR1C4

7.86e-0422392GO:0042448
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C3 AKR1C4

7.86e-0422392GO:1902644
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C3 AKR1C4

8.60e-0423392GO:0034310
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C3 AKR1C4

1.10e-0326392GO:0010566
GeneOntologyBiologicalProcesscartilage development

ZBTB7A COL11A1 COL11A2 GNAS

1.12e-03243394GO:0051216
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

IGSF9B NLGN1

1.19e-0327392GO:0060080
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C3 AKR1C4

1.28e-0328392GO:0048025
GeneOntologyBiologicalProcessdevelopmental maturation

ANKRD17 C1QL2 ZBTB7A NLGN1 RBPJ

1.35e-03439395GO:0021700
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C3 AKR1C4

1.37e-0329392GO:0016093
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C3 AKR1C4

1.37e-0329392GO:0050686
GeneOntologyBiologicalProcessregulation of cell fate specification

SOX17 CHD3

1.37e-0329392GO:0042659
GeneOntologyBiologicalProcesscell fate specification

SOX17 CHD3 RBPJ

1.62e-03123393GO:0001708
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C3 AKR1C4

1.77e-0333392GO:0033119
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

AKR1C3 ZBTB7A AKR1C4

1.85e-03129393GO:0048024
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C3 AKR1C4

1.88e-0334392GO:0006706
GeneOntologyBiologicalProcesspostsynaptic density assembly

C1QL2 NLGN1

1.88e-0334392GO:0097107
GeneOntologyBiologicalProcesscellular response to ketone

AKR1C3 AKR1C4 GNAS

1.89e-03130393GO:1901655
GeneOntologyBiologicalProcesscellular response to alcohol

AKR1C3 AKR1C4 GNAS

1.89e-03130393GO:0097306
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C3 AKR1C4

1.99e-0335392GO:0120255
GeneOntologyBiologicalProcessvitamin metabolic process

AKR1C3 AKR1C4 MTHFD2

2.02e-03133393GO:0006766
GeneOntologyBiologicalProcessheart formation

SOX17 RBPJ

2.11e-0336392GO:0060914
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C3 AKR1C4

2.11e-0336392GO:0008299
GeneOntologyBiologicalProcessendodermal cell differentiation

SOX17 COL5A1

2.35e-0338392GO:0035987
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

AKR1C3 AKR1C4

2.35e-0338392GO:0048384
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C3 AKR1C4

2.60e-0340392GO:0042573
GeneOntologyCellularComponentcollagen trimer

COL5A1 C1QC C1QL2 COL18A1 COL11A1 COL11A2

1.37e-0888396GO:0005581
GeneOntologyCellularComponentcollagen type XI trimer

COL5A1 COL11A1 COL11A2

5.99e-085393GO:0005592
GeneOntologyCellularComponentfibrillar collagen trimer

COL5A1 COL11A1 COL11A2

1.31e-0612393GO:0005583
GeneOntologyCellularComponentbanded collagen fibril

COL5A1 COL11A1 COL11A2

1.31e-0612393GO:0098643
GeneOntologyCellularComponentcomplex of collagen trimers

COL5A1 COL11A1 COL11A2

7.80e-0621393GO:0098644
GeneOntologyCellularComponentcollagen-containing extracellular matrix

COL5A1 C1QC NID2 COL18A1 COL11A1 COL11A2

4.14e-04530396GO:0062023
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

C1QL2 NLGN1

9.12e-0424392GO:0098985
GeneOntologyCellularComponentextracellular matrix

COL5A1 C1QC NID2 COL18A1 COL11A1 COL11A2

1.26e-03656396GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

COL5A1 C1QC NID2 COL18A1 COL11A1 COL11A2

1.28e-03658396GO:0030312
GeneOntologyCellularComponentbasement membrane

COL5A1 NID2 COL18A1

1.52e-03122393GO:0005604
GeneOntologyCellularComponentinhibitory synapse

IGSF9B NLGN1

1.52e-0331392GO:0060077
GeneOntologyCellularComponentsynaptic cleft

C1QL2 NLGN1

1.73e-0333392GO:0043083
GeneOntologyCellularComponentendoplasmic reticulum lumen

COL5A1 COL18A1 COL11A1 COL11A2

3.32e-03332394GO:0005788
DomainCollagen

COL5A1 C1QC C1QL2 COL18A1 COL11A1 COL11A2

1.82e-0885386PF01391
DomainCollagen

COL5A1 C1QC C1QL2 COL18A1 COL11A1 COL11A2

1.82e-0885386IPR008160
DomainTSPN

COL5A1 COL18A1 COL11A1 COL11A2

1.25e-0723384SM00210
DomainNC1_FIB

COL5A1 COL11A1 COL11A2

1.27e-0611383PS51461
DomainFib_collagen_C

COL5A1 COL11A1 COL11A2

1.27e-0611383IPR000885
DomainFib_collagen_C

COL5A1 COL11A1 COL11A2

1.27e-0611383PD002078
DomainCOLFI

COL5A1 COL11A1 COL11A2

1.27e-0611383SM00038
DomainCOLFI

COL5A1 COL11A1 COL11A2

1.27e-0611383PF01410
DomainLamG

COL5A1 COL18A1 COL11A1 COL11A2

1.87e-0644384SM00282
DomainLaminin_G

COL5A1 COL18A1 COL11A1 COL11A2

5.71e-0658384IPR001791
DomainLaminin_G_2

COL5A1 COL11A1 COL11A2

7.29e-0540383PF02210
DomainALDOKETO_REDUCTASE_1

AKR1C3 AKR1C4

1.80e-0410382PS00798
DomainAldo/ket_reductase_CS

AKR1C3 AKR1C4

1.80e-0410382IPR018170
DomainAldo/keto_reductase

AKR1C3 AKR1C4

1.80e-0410382IPR020471
DomainALDOKETO_REDUCTASE_2

AKR1C3 AKR1C4

1.80e-0410382PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C3 AKR1C4

1.80e-0410382PS00063
Domain-

AKR1C3 AKR1C4

4.75e-04163823.20.20.100
DomainNADP_OxRdtase_dom

AKR1C3 AKR1C4

5.38e-0417382IPR023210
DomainAldo_ket_red

AKR1C3 AKR1C4

5.38e-0417382PF00248
DomainAldo/ket_red/Kv-b

AKR1C3 AKR1C4

5.38e-0417382IPR001395
Domain-

COL5A1 COL11A1 COL11A2

9.45e-04953832.60.120.200
DomainConA-like_dom

COL5A1 COL18A1 COL11A1 COL11A2

9.93e-04219384IPR013320
DomainC1Q

C1QC C1QL2

1.92e-0332382SM00110
DomainC1q

C1QC C1QL2

1.92e-0332382PF00386
DomainC1q_dom

C1QC C1QL2

2.17e-0334382IPR001073
DomainC1Q

C1QC C1QL2

2.17e-0334382PS50871
DomainDNA/RNA_helicase_DEAH_CS

CHD3 RTEL1

2.30e-0335382IPR002464
DomainDEAH_ATP_HELICASE

CHD3 RTEL1

2.71e-0338382PS00690
Domain-

C1QC C1QL2

4.64e-03503822.60.120.40
Domain-

SOX17 CHD3

5.59e-03553821.10.30.10
DomainTumour_necrosis_fac-like_dom

C1QC C1QL2

6.20e-0358382IPR008983
DomainP-loop_NTPase

PSMC4 CHD3 GNAS RTEL1 KIFC2 RAB43

6.85e-03848386IPR027417
DomainHMG_box_dom

SOX17 CHD3

7.73e-0365382IPR009071
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL5A1 COL18A1 COL11A1 COL11A2

2.37e-0641334MM15538
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL5A1 COL18A1 COL11A1 COL11A2

3.16e-0644334M27812
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL5A1 COL18A1 COL11A1 COL11A2

5.31e-0650334MM14796
PathwayREACTOME_COLLAGEN_DEGRADATION

COL5A1 COL18A1 COL11A1 COL11A2

6.72e-0653334MM14566
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

COL5A1 COL11A1 COL11A2

1.10e-0519333MM15512
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL5A1 COL18A1 COL11A1 COL11A2

1.18e-0561334M27103
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL5A1 COL18A1 COL11A1 COL11A2

1.18e-0561334MM14637
PathwayREACTOME_COLLAGEN_DEGRADATION

COL5A1 COL18A1 COL11A1 COL11A2

1.43e-0564334M26953
PathwayPID_INTEGRIN1_PATHWAY

COL5A1 COL18A1 COL11A1 COL11A2

1.62e-0566334M18
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL5A1 COL18A1 COL11A1 COL11A2

1.72e-0567334M26999
PathwayREACTOME_COLLAGEN_FORMATION

COL5A1 COL18A1 COL11A1 COL11A2

2.83e-0576334MM14573
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

COL5A1 COL11A1 COL11A2

4.55e-0530333M27772
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

COL5A1 COL11A1 COL11A2

4.55e-0530333MM15517
PathwayREACTOME_COLLAGEN_FORMATION

COL5A1 COL18A1 COL11A1 COL11A2

5.52e-0590334M631
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL5A1 COL11A1 COL11A2

5.53e-0532333MM14924
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

COL5A1 COL11A1 COL11A2

1.17e-0441333M27778
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL5A1 COL18A1 COL11A1 COL11A2

1.39e-04114334MM14571
PathwayPID_SYNDECAN_1_PATHWAY

COL5A1 COL11A1 COL11A2

1.66e-0446333M198
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C3 AKR1C4

1.89e-049332M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C3 AKR1C4

1.89e-049332M47817
PathwayREACTOME_GASTRULATION

SOX17 PSMC4 POU3F1 RBPJ

2.23e-04129334M46433
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C3 AKR1C4

2.88e-0411332M47812
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL5A1 COL18A1 COL11A1 COL11A2

3.05e-04140334M587
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL5A1 NID2 COL18A1 COL11A1 COL11A2

3.08e-04258335MM14572
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL5A1 COL11A1 COL11A2

3.47e-0459333M27218
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4

4.08e-0413332M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4

4.08e-0413332MM14747
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C3 AKR1C4

4.75e-0414332M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4

4.75e-0414332M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C3 AKR1C4

4.75e-0414332M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4

4.75e-0414332MM14748
PathwayREACTOME_SIGNALING_BY_MET

COL5A1 COL11A1 COL11A2

5.06e-0467333MM15345
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C3 AKR1C4

5.47e-0415332MM14870
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL5A1 NID2 COL18A1 COL11A1 COL11A2

6.14e-04300335M610
PathwayPID_AVB3_INTEGRIN_PATHWAY

COL5A1 COL11A1 COL11A2

6.77e-0474333M160
PathwayREACTOME_SIGNALING_BY_MET

COL5A1 COL11A1 COL11A2

8.19e-0479333M27643
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL5A1 COL11A1 COL11A2

9.79e-0484333M7098
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4

1.30e-0323332M1926
PathwayREACTOME_PREDNISONE_ADME

AKR1C3 AKR1C4

1.30e-0323332MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C3 AKR1C4

1.30e-0323332MM14741
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C3 AKR1C4

1.93e-0328332MM15188
PathwayREACTOME_LAMININ_INTERACTIONS

NID2 COL18A1

2.22e-0330332M27216
PathwayREACTOME_DRUG_ADME

AKR1C3 AKR1C4 SLC16A1

2.66e-03119333MM15692
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C3 AKR1C4

2.68e-0333332M5967
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C3 AKR1C4

2.68e-0333332MM14737
Pubmed

Association Between COL5a1, COL11a1, and COL11a2 Gene Variations and Rotator Cuff Tendinopathy in Young Athletes.

COL5A1 COL11A1 COL11A2

1.30e-09339334009784
Pubmed

The Association of Variants within Types V and XI Collagen Genes with Knee Joint Laxity Measurements.

COL5A1 COL11A1 COL11A2

1.30e-09339336553626
Pubmed

Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse.

COL5A1 COL11A1 COL11A2

5.21e-09439317683922
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL5A1 C1QC NID2 COL18A1 COL11A1 COL11A2

8.98e-0913539628675934
Pubmed

Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon.

COL5A1 COL11A1 COL11A2

2.60e-08639321467034
Pubmed

The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains.

COL5A1 COL11A1 COL11A2

2.60e-08639310722718
Pubmed

Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1).

COL5A1 COL11A1 COL11A2

2.60e-0863938563024
Pubmed

The collagen family members as cell adhesion proteins.

COL5A1 COL11A1 COL11A2

2.60e-08639317876790
Pubmed

The pro-alpha2(XI) collagen gene is expressed in odontoblasts.

COL5A1 COL11A1 COL11A2

7.27e-08839320059976
Pubmed

Ultrastructural localization of collagen types II, IX, and XI in the growth plate of human rib and fetal bovine epiphyseal cartilage: type XI collagen is restricted to thin fibrils.

COL11A1 COL11A2

1.23e-0623927560887
Pubmed

Collagen XI sequence variations in nonsyndromic cleft palate, Robin sequence and micrognathia.

COL11A1 COL11A2

1.23e-06239212673280
Pubmed

Genetic Association Study Between the COL11A1 and COL18A1 Genes and High Myopia in a Han Chinese Population.

COL18A1 COL11A1

1.23e-06239229781737
Pubmed

Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.

AKR1C3 AKR1C4

1.23e-0623927650035
Pubmed

Exon-Trapping Assay Improves Clinical Interpretation of COL11A1 and COL11A2 Intronic Variants in Stickler Syndrome Type 2 and Otospondylomegaepiphyseal Dysplasia.

COL11A1 COL11A2

1.23e-06239233348901
Pubmed

Structure of a full-length cDNA clone for the pro-alpha1(V/XI) collagen chain of red seabream.

COL5A1 COL11A1

1.23e-06239211342118
Pubmed

Immature osteoblastic cells express the pro-alpha2(XI) collagen gene during bone formation in vitro and in vivo.

COL11A1 COL11A2

1.23e-06239211780999
Pubmed

Alternative mRNA processing occurs in the variable region of the pro-alpha 1(XI) and pro-alpha 2(XI) collagen chains.

COL11A1 COL11A2

1.23e-0623927721876
Pubmed

Differential in situ expression of alpha2(XI) collagen mRNA isoforms in the developing mouse.

COL11A1 COL11A2

1.23e-0623929560475
Pubmed

The human alpha 2(XI) collagen gene (COL11A2) maps to the centromeric border of the major histocompatibility complex on chromosome 6.

COL11A1 COL11A2

1.23e-0623922591970
Pubmed

Immunohistochemical localization of collagen type XI alpha1 and alpha2 chains in human colon tissue.

COL11A1 COL11A2

1.23e-06239218040076
Pubmed

Novel pathogenic COL11A1/COL11A2 variants in Stickler syndrome detected by targeted NGS and exome sequencing.

COL11A1 COL11A2

1.23e-06239225240749
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

COL5A1 NID2 COL18A1 COL11A1 COL11A2

1.53e-0617539528071719
Pubmed

Human transcription factor protein interaction networks.

SOX17 PSMC4 ANKRD17 ZBTB7A SSBP2 CHD3 CEP192 KMT2B KAT14 RBPJ

2.84e-061429391035140242
Pubmed

Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.

COL5A1 COL11A1 COL11A2

2.95e-062539319180518
Pubmed

Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.

AKR1C3 AKR1C4

3.67e-0633927626489
Pubmed

Col11a1 and Col11a2 mRNA expression in the developing mouse cochlea: implications for the correlation of hearing loss phenotype with mutant type XI collagen genotype.

COL11A1 COL11A2

3.67e-06339215141750
Pubmed

cDNA sequence and expression of the mouse alpha1(V) collagen gene (Col5a1).

COL5A1 COL11A1

3.67e-0633929582436
Pubmed

Diurnal regulation of metabolism by Gs-alpha in hypothalamic QPLOT neurons.

OPN5 GNAS

3.67e-06339237141220
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ANKRD17 COL5A1 COL18A1 ZBTB7A CHD3 IGSF9B CEP192 GNAS NUMBL RTEL1

4.09e-061489391028611215
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

COL5A1 NID2 COL18A1

4.67e-062939322613833
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C3 AKR1C4

7.34e-06439220124700
Pubmed

A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population.

COL18A1 COL11A1

7.34e-06439221527992
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C3 AKR1C4

7.34e-06439210702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C3 AKR1C4

7.34e-06439217034817
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C3 AKR1C4

7.34e-06439210500239
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C3 AKR1C4

7.34e-06439216508162
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C3 AKR1C4

7.34e-06439219487289
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C3 AKR1C4

7.34e-06439217629694
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4

7.34e-06439214967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C3 AKR1C4

7.34e-06439210393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C3 AKR1C4

7.34e-06439215193432
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C3 AKR1C4

7.34e-06439229764944
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C3 AKR1C4

7.34e-06439210526179
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C3 AKR1C4

7.34e-06439217888864
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C3 AKR1C4

7.34e-06439231479646
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C3 AKR1C4

7.34e-06439217442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C3 AKR1C4

7.34e-06439228329705
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C3 AKR1C4

7.34e-06439216018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4

7.34e-06439217272929
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C3 AKR1C4

7.34e-06439219237748
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C3 AKR1C4

7.34e-06439218667791
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C3 AKR1C4

7.34e-06439215222881
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C3 AKR1C4

7.34e-06439228259989
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C3 AKR1C4

7.34e-06439216191478
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C3 AKR1C4

7.34e-06439221521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4

7.34e-0643928274401
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4

7.34e-06439216511129
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C3 AKR1C4

7.34e-06439210803568
Pubmed

Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia.

COL5A1 COL11A2

7.34e-06439223624467
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C3 AKR1C4

7.34e-06439234590152
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C3 AKR1C4

7.34e-06439215577209
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C3 AKR1C4

7.34e-0643927789999
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

COL5A1 C1QC NID2 COL18A1 COL11A1

8.36e-0624839524006456
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C3 AKR1C4

1.22e-0553927737980
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C3 AKR1C4

1.22e-05539210672042
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C3 AKR1C4

1.22e-05539221851338
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C3 AKR1C4

1.22e-05539238788959
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C3 AKR1C4

1.22e-05539217872381
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C3 AKR1C4

1.22e-05539216984997
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C3 AKR1C4

1.22e-05539217064890
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C3 AKR1C4

1.22e-05539218003893
Pubmed

Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality.

COL11A1 COL11A2

1.83e-05639238461417
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C3 AKR1C4

1.83e-05639229107092
Pubmed

ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development.

COL5A1 COL11A1

1.83e-05639217029294
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C3 AKR1C4

1.83e-05639226748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C3 AKR1C4

1.83e-05639217122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C3 AKR1C4

1.83e-05639217255200
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C3 AKR1C4

1.83e-05639219273550
Pubmed

The role of sequence variations within the genes encoding collagen II, IX and XI in non-syndromic, early-onset osteoarthritis.

COL11A1 COL11A2

1.83e-05639215922184
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C3 AKR1C4

1.83e-05639215860270
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C3 AKR1C4

1.83e-05639215471942
Pubmed

SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling.

NUMBL RBPJ

1.83e-05639237843276
Pubmed

The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation.

COL11A1 COL11A2

1.83e-05639222492985
Pubmed

Stickler Syndrome

COL11A1 COL11A2

1.83e-05639220301479
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKR1C3 ANKRD17 COL18A1 CHD3 CEP192 AKR1C4 KIFC2 RBPJ

2.26e-05108439811544199
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

COL5A1 NID2 COL18A1

2.46e-055039323658023
Pubmed

Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.

ZBTB7A CHD3

2.56e-05739226816381
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C3 AKR1C4

2.56e-05739234843575
Pubmed

Reciprocal signalling by Notch-Collagen V-CALCR retains muscle stem cells in their niche.

COL5A1 RBPJ

2.56e-05739229795344
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C3 AKR1C4

2.56e-05739222529366
Pubmed

A comparative analysis of the fibulin protein family. Biochemical characterization, binding interactions, and tissue localization.

NID2 COL18A1

2.56e-05739217324935
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C3 AKR1C4

2.56e-05739233127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C3 AKR1C4

2.56e-05739212562828
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C3 AKR1C4

2.56e-05739226160177
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C3 AKR1C4

2.56e-05739216337335
Pubmed

Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling.

NUMBL RBPJ

2.56e-05739225535389
Pubmed

Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance.

COL5A1 COL11A1

3.42e-05839218816857
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C3 AKR1C4

3.42e-05839220837989
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C3 AKR1C4

3.42e-05839233584538
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C3 AKR1C4

3.42e-0583929224647
Cytoband20q13.3

GNAS RTEL1

1.32e-042039220q13.3
Cytoband4p15.2

STIM2 RBPJ

2.62e-04283924p15.2
Cytoband1p34.1

POU3F1 CCDC17

1.09e-03573921p34.1
CytobandEnsembl 112 genes in cytogenetic band chr10p15

AKR1C3 AKR1C4

2.69e-0390392chr10p15
CytobandEnsembl 112 genes in cytogenetic band chr4p15

STIM2 RBPJ

5.92e-03135392chr4p15
GeneFamilyCollagens

COL5A1 COL18A1 COL11A1 COL11A2

9.57e-0746304490
GeneFamilyAldo-keto reductases

AKR1C3 AKR1C4

2.76e-0415302399
CoexpressionNABA_COLLAGENS

COL5A1 COL18A1 COL11A1 COL11A2

4.45e-0743384MM17060
CoexpressionNABA_COLLAGENS

COL5A1 COL18A1 COL11A1 COL11A2

4.89e-0744384M3005
CoexpressionNABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS

COL5A1 NID2 COL11A2

1.00e-0529383MM17055
CoexpressionNABA_CORE_MATRISOME

COL5A1 NID2 COL18A1 COL11A1 COL11A2

4.25e-05270385MM17057
CoexpressionNABA_CORE_MATRISOME

COL5A1 NID2 COL18A1 COL11A1 COL11A2

4.63e-05275385M5884
CoexpressionTABULA_MURIS_SENIS_MESENTERIC_ADIPOSE_TISSUE_MESENCHYMAL_STEM_CELL_OF_ADIPOSE_AGEING

AKR1C3 C1QC ZBTB7A AKR1C4 GNAS KMT2B NUMBL

5.03e-05685387MM3782
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

SOX17 NID2 GNAS SLC16A1

9.68e-05166384M1542
CoexpressionANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE

COL5A1 NID2 COL11A1

1.10e-0464383M2572
CoexpressionLIAO_METASTASIS

SSBP2 COL11A2 GNAS NUMBL MTHFD2 KIFC2

1.17e-04540386M13809
CoexpressionYAMAZAKI_TCEB3_TARGETS_UP

SOX17 NID2 GNAS SLC16A1

1.29e-04179384MM660
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

OPN5 CHD3 STIM2 IGSF9B COL11A1 NLGN1 CCDC17 KIFC2

1.55e-041106388M39071
CoexpressionMIKKELSEN_MCV6_ICP_WITH_H3K27ME3

SOX17 COL11A2 SCN4A

1.77e-0475383M1956
CoexpressionGSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_UP

COL18A1 POU3F1 NPHP4 ZNF710

1.91e-04198384M8878
CoexpressionGSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN

NID2 POU3F1 COL11A2 GNAS

1.98e-04200384M9668
CoexpressionMIKKELSEN_MCV6_ICP_WITH_H3K27ME3

SOX17 COL11A2 SCN4A

2.65e-0486383MM834
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C3 AKR1C4

2.75e-0417382MM826
CoexpressionRAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP

AKR1C3 NID2 CHD3 AKR1C4

2.80e-04219384MM1237
CoexpressionZAMORA_NOS2_TARGETS_DN

SOX17 AKR1C3 AKR1C4

2.93e-0489383MM690
CoexpressionJIANG_MELANOMA_TRM7_CD8

ZBTB7A CHD3 RBPJ

3.03e-0490383M48971
CoexpressionNABA_MATRISOME_HIGHLY_METASTATIC_MELANOMA

COL5A1 COL11A2

3.09e-0418382M47984
ToppCell(3)_Chondrocytes-(31)_Chondro-hyper|World / Cell class and subclass of bone marrow stroma cells in homeostatis

NID2 ACOT1 COL11A1 COL11A2 MTHFD2

6.36e-07189395394b153393904c3dba51a6bfe338afd554e66649
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL18A1 COL11A1 NLGN1 NUMBL RAB43

8.41e-072003954c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCelllymphoid-B_cell-pro-B|World / Lineage, cell class and subclass

COL5A1 NID2 POU3F1 SSBP2

1.18e-0516139423138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL2 POU3F1 NLGN1 C1orf94

1.83e-05180394fa819df81fca95c2cc602fede635cb03e3f35fad
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL2 POU3F1 NLGN1 C1orf94

1.83e-05180394907cd510fd2e21532ce04ba687e8894f7af71f27
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 ACOT1 IGSF9B NLGN1

1.91e-05182394c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL5A1 NID2 COL18A1 COL11A1

2.03e-0518539487c416d14ca6255bee39b16e7571553e36ee3069
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKR1C3 C1QL2 IGSF9B COL11A1

2.26e-051903946c7e1086c0a274cd5527c3104106e372811c9905
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL5A1 C1QC COL11A1 COL11A2

2.26e-05190394cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCell(3)_Chondrocytes-(33)_Chondro-prol/rest|World / Cell class and subclass of bone marrow stroma cells in homeostatis

NID2 COL11A1 COL11A2 MTHFD2

2.45e-05194394c093c5e161b97ad770bfbaad3023eba4537101b5
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NDUFA13 COL11A1 COL11A2 KAT14

2.45e-0519439440c6e17e9e48d4fa6da3a0a1066c4c6565a1e096
ToppCelldroplet-Limb_Muscle-MUSCLE-1m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL11A1 COL11A2 MTHFD2

2.50e-05195394fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKR1C3 C1QL2 IGSF9B COL11A1

2.55e-05196394671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL11A1 NUMBL MTHFD2

2.55e-0519639459b5b5a0c123d0423abd19c312514849004b903b
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKR1C3 C1QL2 IGSF9B COL11A1

2.55e-05196394f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL11A1 NUMBL MTHFD2

2.60e-05197394b16add329bb35a558287ede51353010dde5bc029
ToppCell(4)_Endothelial_cells-(41)_EC-arteriolar|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

SOX17 NID2 COL18A1 GNAS

2.60e-05197394482e3f8926880afed88ed37553ed2b5ed58b8c99
ToppCelldroplet-Heart-HEART|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFA13 COL11A1 GNAS MTHFD2

2.60e-051973949654472f1d4c9a6caadf1ff61a84902d171e9eb4
ToppCelldroplet-Heart-HEART-1m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDUFA13 COL11A1 GNAS MTHFD2

2.60e-051973941ec3c05a5d4163df2cf0d168e28a3f1d35364da2
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL5A1 NID2 COL18A1 COL11A1

2.65e-05198394eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKR1C3 C1QC GNAS MTHFD2

2.65e-05198394885cbd3695b466a161cf318d35ebbdfcc0c19cec
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL5A1 NID2 COL18A1 COL11A1

2.65e-051983948b9e8eaeffda40912a0163fdf39b93bc5e64751c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 COL11A1 COL11A2 NUMBL

2.65e-051983941b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

COL5A1 C1QC SLC16A1 MTHFD2

2.65e-0519839465875fbd99393cdd62595c713ab90db06d28081f
ToppCellmetastatic_Brain-Fibroblasts|metastatic_Brain / Location, Cell class and cell subclass

COL5A1 NID2 COL18A1 COL11A1

2.71e-0519939463eb2106bb6e2e33d020628583536c8d96662c84
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

COL18A1 COL11A1 NLGN1 RAB43

2.76e-0520039436de49593cf6ff1c9229fcceb150c1d68658a360
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL5A1 NID2 COL18A1 COL11A1

2.76e-052003944f7e26b27bd51c32420ed8c2f52d070aee542159
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Npw|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

POU3F1 ACOT1 IGSF9B

1.32e-04113393165de4316059222f33d1e51aeff4554037c0b937
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

C1QL2 COL18A1 COL11A2

2.14e-0413339363d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

AKR1C3 ANKRD17 GNAS

2.38e-04138393817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

C1QL2 POU3F1 NLGN1

2.70e-0414439308005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE|Entopeduncular / BrainAtlas - Mouse McCarroll V32

POU3F1 COL11A2 C1orf94

2.81e-04146393a317f14a1aab11ffcce65baeb1c475c04324315f
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

COL5A1 COL11A2 MTHFD2

2.86e-0414739387c24843cb0e87ad42e725d08423131a5d2d25a3
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

COL5A1 STIM2 C1orf94

3.22e-04153393b37a1ecad389d2848b8ca4d287823e8048207420
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

COL5A1 NID2 SSBP2

3.28e-041543938a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL18A1 STIM2 SLC16A1

3.35e-041553937aba8ef53c9170ad8ed955c904c8991097ab1e32
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 IGSF9B COL11A1

3.41e-04156393abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 IGSF9B COL11A1

3.41e-04156393dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL18A1 COL11A1 SLC16A1

3.41e-0415639360f1ce38e34b582f589db1e0d6139282c1902b2b
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

COL5A1 COL11A2 MTHFD2

3.67e-04160393ab769516f9f7798d1390ef215caf22a2d3d53e63
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|(1)_Control_(PBS) / Stress and Cell class

COL5A1 COL11A2 MTHFD2

3.67e-041603938450466fc2465c56798df2b520edd23c2c2e941c
ToppCelldroplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QC COL11A2 RBPJ

3.74e-04161393f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCelldroplet-Lung-nan-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QC COL11A2 RBPJ

3.74e-04161393110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C1QC RAB43 RBPJ

3.88e-041633937af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL2 IGSF9B COL11A2

4.02e-041653931703d3eb644b3c743ad3c5532b1d29ea010c79c8
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 COL11A1 COL11A2

4.09e-0416639337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NID2 COL11A1 COL11A2

4.09e-0416639381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACOT1 KAT14 KIFC2

4.16e-04167393881f64db8dea3faa7588bf04d87c20924a4e5952
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL5A1 POU3F1 CEP192

4.38e-04170393ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 C1QC COL18A1

4.38e-0417039337c647f67505aa1ff12a198df1eeddd9f406fe15
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL5A1 C1QC COL18A1

4.38e-04170393b180ec9a1b79025a180c8559c27c31272410dea8
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

COL18A1 SSBP2 NLGN1

4.46e-0417139370963f79711fe6088d6d01b29206b17ab89e5e73
ToppCellP07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 COL18A1 POU3F1

4.53e-041723938d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

C1QC NID2 CCDC17

4.53e-04172393afa36501d48b1456c511fa0d5d326ec05bdc380f
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

COL18A1 SSBP2 NLGN1

4.53e-0417239384d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

COL18A1 SSBP2 GNAS

4.53e-04172393644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCellIonocyte-iono-2|World / Class top

COL18A1 COL11A2 GNAS

4.61e-04173393e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

COL5A1 COL11A2 MTHFD2

4.61e-04173393c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 IGSF9B RTEL1

4.69e-041743936987fe7959afce347282f632abc16d800ccab7c4
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-ILC|Multiple_Sclerosis / Disease, Lineage and Cell Type

SSBP2 COL11A2 KIFC2

4.69e-041743937c50bf9da37711266cc077eef4e54b58463f1d37
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

SOX17 COL5A1 CHD3

4.69e-04174393fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

C1QC RTEL1 RBPJ

4.77e-04175393d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL2 IGSF9B NLGN1

4.77e-041753931d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL11A1 COL11A2 SLC16A1

4.77e-04175393085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1QL2 IGSF9B NLGN1

4.77e-04175393d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL5A1 NID2 COL18A1

4.85e-041763932015539c58aa0bb118e111ffedd63dd9fe863bb1
ToppCelldroplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MTHFD2 RAB43 RBPJ

4.85e-041763937d1e2627d7ec5ddd6c87c55d2a6879255b76949e
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NID2 POU3F1 COL11A1

4.85e-04176393792f414f5092aba14260b8e16378e793a822498e
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SSBP2 CHD3 SCN4A

5.01e-0417839371ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

POU3F1 STIM2 SLC16A1

5.01e-04178393f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCellEntopeduncular-Macroglia|Entopeduncular / BrainAtlas - Mouse McCarroll V32

POU3F1 ACOT1 COL11A2

5.09e-04179393f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCellMesenchymal_cells-Chondrocytes|Mesenchymal_cells / Lineage and Cell class

NID2 COL11A1 COL11A2

5.18e-041803936e399368430ef3afa9ce1ef0ed90f614ccef9987
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

COL5A1 COL11A2 MTHFD2

5.26e-0418139356ae86072858c156681507aecd1bc6cb0a3372d2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NID2 NLGN1

5.26e-041813936956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 IGSF9B COL11A1

5.26e-041813935f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NID2 COL11A1

5.26e-04181393c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

COL5A1 NID2 COL11A1

5.26e-04181393c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 IGSF9B COL11A1

5.26e-04181393c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL11A1 COL11A2 NUMBL

5.35e-04182393bb7de0c93d8f59f13c990e425139b9348ca8027e
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 ACOT1 IGSF9B

5.35e-04182393d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular-Chondrocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL11A1 COL11A2 NUMBL

5.35e-04182393507f095af4dff60f2c2b64d750477154084c3595
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 ACOT1 IGSF9B

5.35e-04182393e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POU3F1 COL11A1 COL11A2

5.35e-04182393a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellcellseq-Mesenchymal-Chondrocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL11A1 COL11A2 NUMBL

5.35e-0418239388bd17c07bd8443a0ede4e9dc7bc9d1230b42211
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKR1C3 COL11A2 CCDC17

5.35e-04182393b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 ACOT1 IGSF9B

5.35e-0418239382ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 IGSF9B NLGN1

5.35e-04182393a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL11A1 COL11A2 KAT14

5.35e-0418239300a148b1e499bf16325491536d187d4dd6b70c06
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

COL5A1 SSBP2 NLGN1

5.43e-04183393de08f9ea02b7244d5a8788064631d10f06565337
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NID2 COL11A1 COL11A2

5.43e-041833931464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCellwk_15-18-Epithelial-PNS-intermediate_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL18A1 POU3F1 IGSF9B

5.43e-04183393d874aa9a856f79626c8a8371f6196a77b7d662ee
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL5A1 C1QL2 POU3F1

5.52e-0418439330fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL5A1 C1QL2 POU3F1

5.52e-0418439396926efa220f03d0787322c9519bb9e8f64f74d0
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

NID2 COL11A1 COL11A2

5.52e-041843931e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SSBP2 STIM2 GNAS

5.52e-041843938fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 COL18A1 COL11A2

5.61e-041853933a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 IGSF9B KIFC2

5.61e-0418539311c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

AKR1C3 C1QC ACOT1

5.61e-0418539385cb81759589a26d83676cffbf2bc37399683c10
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NID2 COL18A1 COL11A2

5.61e-04185393224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL5A1 NID2 COL18A1

5.69e-041863930c477016c1b539b3086a8066c3c6443f08c222a3
DrugGK-101

COL5A1 COL18A1 COL11A1 COL11A2

4.16e-0736394CID000161853
DrugDisopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

COL5A1 COL18A1 CHD3 NPHP4 SLC16A1 ZNF710

1.03e-061983967035_UP
DrugMadecassol

COL5A1 COL18A1 COL11A1 COL11A2

1.14e-0646394CID000108062
Drughydroxylysine

COL5A1 C1QC COL18A1 COL11A1 COL11A2

1.16e-06109395CID000001029
DrugAC1L1C2F

COL5A1 NID2 COL18A1 COL11A1 COL11A2

1.21e-06110395CID000001711
Drugd-indobufen

COL5A1 COL18A1 COL11A1 COL11A2

1.60e-0650394CID000044562
Drugridogrel

COL5A1 COL18A1 COL11A1 COL11A2

1.88e-0652394CID005362391
DrugNSC49633

COL5A1 COL18A1 COL11A1 COL11A2

2.03e-0653394CID000023340
DrugAC1LAKND

COL5A1 COL18A1 COL11A1 COL11A2

3.82e-0662394CID000470146
Drug351A

COL5A1 COL11A1 COL11A2

5.19e-0620393CID000122144
DrugBAPN

COL5A1 COL18A1 COL11A1 COL11A2

6.57e-0671394CID000001647
Drugmalotilate

COL5A1 COL18A1 COL11A1 COL11A2

6.57e-0671394CID000004006
DrugL-3,4-dehydroproline

COL5A1 COL18A1 COL11A1 SCN4A

7.35e-0673394CID000094284
DrugAC1NMZ1B

COL5A1 COL18A1 COL11A1 COL11A2

8.18e-0675394CID005034185
Drugstrontium ranelate

COL5A1 COL18A1 COL11A1 COL11A2

9.09e-0677394CID006918182
Drughalofuginone lactate

COL5A1 COL18A1 COL11A1 COL11A2

1.35e-0585394CID000062891
DrugPregnanes

AKR1C3 AKR1C4

1.71e-054392ctd:D011278
Drugtetralol

AKR1C3 AKR1C4

1.71e-054392ctd:C019106
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C3 AKR1C4

1.71e-054392ctd:C018156
Drugcloxazolam

AKR1C3 AKR1C4

1.71e-054392ctd:C005522
DrugDBD-H

AKR1C3 AKR1C4

1.71e-054392CID000131382
Drug4-hydroxyproline

COL5A1 COL18A1 COL11A1 COL11A2

1.76e-0591394CID000000825
Drugisodesmosine

COL5A1 COL11A1 COL11A2

2.45e-0533393CID000013811
DrugHydroxysteroids

AKR1C3 AKR1C4

2.85e-055392ctd:D006914
Drugcresolphthalein

AKR1C3 AKR1C4

2.85e-055392ctd:C010092
Drugticlopidine

COL5A1 COL18A1 COL11A1 COL11A2

2.88e-05103394CID000005472
DrugPPACK

COL5A1 COL18A1 COL11A1 COL11A2

4.14e-05113394CID003036757
DrugBPAT-143

COL5A1 COL11A1

4.27e-056392CID000146249
DrugAC1L93E5

AKR1C3 AKR1C4

4.27e-056392CID000412383
DrugMedazepam

AKR1C3 AKR1C4

4.27e-056392ctd:D008472
Drug3-hydroxyhexobarbital

AKR1C3 AKR1C4

4.27e-056392CID000439898
DrugB-Ms

COL5A1 NID2 COL18A1 RBPJ

4.28e-05114394CID000445091
DrugAC1L9732

COL5A1 COL18A1 COL11A1 COL11A2

4.28e-05114394CID000439300
DrugAC1Q6PCP

COL5A1 COL18A1 COL11A1 COL11A2 GNAS

4.38e-05230395CID000005267
DrugTranilast sodium

COL5A1 COL18A1 COL11A1 COL11A2

4.43e-05115394CID000005527
DrugPD123177

COL5A1 COL11A1 COL11A2

5.47e-0543393CID000114899
DrugNC-4

COL5A1 COL11A1 COL11A2

5.86e-0544393CID006420119
DrugSelara

COL5A1 COL18A1 COL11A1 COL11A2

6.14e-05125394CID000150310
DrugDMSe

COL5A1 COL18A1 COL11A1 COL11A2

7.59e-05132394CID000020796
Drug2-cyclohexen-1-ol

AKR1C3 AKR1C4

7.95e-058392CID000013198
DrugNitrazepam

AKR1C3 AKR1C4

7.95e-058392ctd:D009567
Drugpirfenidone

COL5A1 COL18A1 COL11A1 COL11A2

9.01e-05138394CID000040632
DrugDL-penicillamine

COL5A1 COL18A1 COL11A1 COL11A2

9.27e-05139394CID000004727
DrugPCR 4099

COL5A1 COL18A1 COL11A1 COL11A2

9.27e-05139394CID000002806
Drug4-hydroxybenzoic acid

AKR1C3 AKR1C4

1.02e-049392ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C3 AKR1C4

1.02e-049392ctd:D004092
Drugdesmosine

COL5A1 COL11A1 COL11A2

1.03e-0453393CID000025435
DrugNADH

AKR1C3 NDUFA13 AKR1C4 MTHFD2

1.06e-04144394DB00157
Drugcandesartan cilexetil

COL5A1 COL18A1 COL11A1 COL11A2

1.09e-04145394CID000002540
DrugHexestrol

AKR1C3 SSBP2 AKR1C4

1.15e-0455393ctd:D006589
Drug1h00

COL5A1 COL11A1 COL11A2

1.21e-0456393CID000445950
Drugoctyl gallate

AKR1C3 AKR1C4

1.28e-0410392ctd:C016627
DrugN-isopropyl-p-iodoamphetamine

GNAS RBPJ

1.56e-0411392CID000003729
DrugDihydroxydihydrobenzopyrenes

AKR1C3 AKR1C4

1.56e-0411392ctd:D004101
Drugchlordecone alcohol

AKR1C3 AKR1C4

1.56e-0411392CID000013946
DrugL-lysyl-L-lysyl-L-lysine

COL5A1 COL18A1 COL11A1 COL11A2

1.67e-04162394CID000072363
DrugPhenolphthalein

AKR1C3 AKR1C4

1.87e-0412392ctd:D020113
Drug(2s,5s)-5-Carboxymethylproline

NDUFA13 COL5A1 COL18A1 COL11A1 COL11A2

1.89e-04314395CID000447989
Drugkhellin

COL5A1 COL18A1 COL11A1 COL11A2

2.06e-04171394CID000003828
DrugAlendronate

COL5A1 COL11A1 SCN4A

2.16e-0468393ctd:D019386
DrugDMBA-3,4-dihydrodiol

AKR1C3 AKR1C4

2.20e-0413392CID000050096
Drugflunisolide

AKR1C3 AKR1C4

2.20e-0413392ctd:C007734
DrugAC1L1DD6

COL5A1 COL18A1 COL11A1 COL11A2

2.45e-04179394CID000002299
Drug1-acenaphthenol

AKR1C3 AKR1C4

2.57e-0414392CID000022750
Drug5-alpha-Dihydroprogesterone

AKR1C3 AKR1C4

2.57e-0414392ctd:D043582
DrugMeclofenamic Acid

AKR1C3 AKR1C4

2.57e-0414392ctd:D008469
Drug5 alpha-androstane-3 beta,17 beta-diol

AKR1C3 COL11A1 AKR1C4 COL11A2

2.78e-04185394CID000011301
Drugreduced diphosphopyridine nucleotide

AKR1C3 NDUFA13 COL18A1 AKR1C4 MTHFD2

2.81e-04342395CID000000928
Drug12(S)-hydroxyeicosatetraenoic acid

COL5A1 COL18A1 COL11A1 COL11A2

3.01e-04189394CID000001413
Drugfoscarnet

COL5A1 COL18A1 COL11A1 COL11A2

3.08e-04190394CID000003414
DrugMethotrexate [59-05-2]; Down 200; 8.8uM; PC3; HT_HG-U133A

COL5A1 COL18A1 NLGN1 ZNF710

3.08e-041903946318_DN
DrugCinchonine [118-10-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A

COL5A1 ZBTB7A RTEL1 ZNF710

3.14e-041913942789_DN
Drugalpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT_HG-U133A

COL5A1 POU3F1 SSBP2 SCN4A

3.33e-041943944531_UP
Drug9-cis-retinal

AKR1C3 AKR1C4

3.38e-0416392ctd:C031390
Drugrhamnose

COL5A1 ZBTB7A COL11A1 COL11A2 RBPJ

3.38e-04356395CID000000840
DrugDyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A

AKR1C3 CHD3 NLGN1 KMT2B

3.39e-041953947022_UP
DrugIoxaglic acid [59017-64-0]; Down 200; 3.2uM; MCF7; HT_HG-U133A

COL5A1 KMT2B SLC16A1 RTEL1

3.46e-041963947470_DN
DrugHexamethonium dibromide dihydrate [55-97-0]; Up 200; 10uM; HL60; HG-U133A

CHD3 GNAS NPHP4 RTEL1

3.46e-041963941982_UP
DrugDoxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A

COL5A1 COL11A1 AKR1C4 RTEL1

3.46e-041963945671_UP
DrugSulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A

ZBTB7A NLGN1 NPHP4 RTEL1

3.46e-041963943218_DN
DrugCanrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A

COL5A1 SSBP2 SLC16A1 ZNF710

3.60e-041983942065_UP
DrugReserpinic acid hydrochloride; Down 200; 9.2uM; PC3; HT_HG-U133A

COL5A1 CHD3 KMT2B RTEL1

3.60e-041983946603_DN
DrugChlorhexidine [55-56-1]; Down 200; 8uM; PC3; HT_HG-U133A

CHD3 GNAS RTEL1 ZNF710

3.60e-041983946302_DN
DrugDelsoline [509-18-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A

COL18A1 CHD3 KMT2B NPHP4

3.67e-041993947212_DN
DrugAcenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A

COL5A1 ZBTB7A SLC16A1 ZNF710

3.74e-042003942077_UP
DrugEdrophonium chloride [116-38-1]; Down 200; 19.8uM; MCF7; HT_HG-U133A

COL18A1 ZBTB7A RTEL1 ZNF710

3.74e-042003945001_DN
DrugPF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A

COL5A1 KMT2B RTEL1 ZNF710

3.74e-042003946907_DN
Drugbeta-Naphthoflavone

AKR1C3 PSMC4 NID2 COL18A1 POU3F1 ACOT1 SLC16A1

4.56e-04828397ctd:D019324
Drugoxcarbazepine

AKR1C3 AKR1C4

4.80e-0419392ctd:C036006
DrugAC1L9HPX

AKR1C3 COL5A1 COL11A2

5.25e-0492393CID000445279
Drugbenzo(a)pyrene-7,8-dione

AKR1C3 AKR1C4

5.33e-0420392ctd:C076588
DrugChrysenes

AKR1C3 AKR1C4

5.33e-0420392ctd:D002911
DrugAGN-1133

COL5A1 COL18A1 COL11A1

5.42e-0493393CID000015178
DrugFlunitrazepam

AKR1C3 AKR1C4

5.88e-0421392ctd:D005445
Drugbenzene dihydrodiol

AKR1C3 AKR1C4

6.46e-0422392CID000000418
Drugalpha-L-rhamnoside

SOX17 COL11A1 COL11A2

6.50e-0499393CID000019233
Drugpyridinoline

COL5A1 COL11A1 COL11A2

6.50e-0499393CID000105068
Drugchondroitin sulfate

COL5A1 COL18A1 COL11A1 COL11A2 NLGN1

6.64e-04413395CID000024766
DiseaseFibrochondrogenesis

COL11A1 COL11A2

1.61e-062382C0265282
DiseaseStickler syndrome (implicated_via_orthology)

COL11A1 COL11A2

1.61e-062382DOID:0080046 (implicated_via_orthology)
DiseaseStickler syndrome

COL11A1 COL11A2

1.61e-055382cv:C0265253
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

COL5A1 COL18A1 COL11A1

4.42e-0553383C4707243
Diseaseglioblastoma multiforme

SSBP2 RTEL1

5.78e-059382EFO_0000519
Diseasewaist-hip ratio

COL5A1 NID2 COL18A1 CEP192 COL11A1 RAB43 SCN4A RBPJ

1.40e-041226388EFO_0004343
Diseasetriacylglycerol 54:6 measurement

C1QL2 NLGN1

3.67e-0422382EFO_0010424
DiseaseHeadache, type 2 diabetes mellitus

NLGN1 RBPJ

4.02e-0423382HP_0002315, MONDO_0005148
Diseaseage-related hearing impairment

NID2 COL11A2 NLGN1 CCDC17

7.85e-04324384EFO_0005782
DiseaseHereditary hearing loss and deafness

COL11A1 COL11A2 SCN4A

8.82e-04146383cv:C0236038
Diseasetriglyceride measurement, response to diuretic

COL11A1 C1orf94

8.83e-0434382EFO_0004530, GO_0036270
Diseasecolorectal adenocarcinoma (is_implicated_in)

KMT2B CCDC17

9.35e-0435382DOID:0050861 (is_implicated_in)
DiseaseProstatic Neoplasms

AKR1C3 COL5A1 ZBTB7A SSBP2 CHD3

1.11e-03616385C0033578
DiseaseMalignant neoplasm of prostate

AKR1C3 COL5A1 ZBTB7A SSBP2 CHD3

1.11e-03616385C0376358

Protein segments in the cluster

PeptideGeneStartEntry
PPEPGPFPGIVDMFG

ACOT1

151

Q86TX2
MPVLGFGTYAPPEVP

AKR1C4

16

P17516
MLGPAPYDPGAGLVI

CCDC17

386

Q96LX7
MPVLGFGTYAPPEVP

AKR1C3

16

P42330
DPPLMAGDGPQYLFP

C1orf94

556

Q6P1W5
YGNAMIPPVAPIPDG

ANKRD17

2536

O75179
GLGYPPMPRVPVVGI

NUMBL

496

Q9Y6R0
MAGPGPGPGDPDEQY

RAB43

1

Q86YS6
MPPAVGGPVGYTPPD

SLC16A1

1

P53985
PAVVEPGMLVEGPPG

COL11A1

431

P12107
PGPPGPVVYVSEQDG

COL18A1

1121

P39060
GVIDPGMEYVPPPAG

KAT14

376

Q9H8E8
VKQDMPPPGGYGPID

NDUFA13

6

Q9P0J0
MPLVGLGDYVPEPFG

OPN5

166

Q6U736
LEPGMLVEGPPGPEG

COL11A2

391

P13942
PPMDDVYAPGELGPG

POU3F1

406

Q03052
FVKMAGEGEPVPPPV

KMT2B

2201

Q9UMN6
GDEVPYVLGIPMIGP

NLGN1

546

Q8N2Q7
FPGAPVGMLGEDPPV

NPHP4

1156

O75161
QPYPDGGPVPSEMDV

NID2

421

Q14112
PMGIPGEPGEEGRYK

C1QC

101

P02747
MICDPYTAAPGGEPP

C1QL2

31

Q7Z5L3
VPGVPGEMEPEPGYR

CHD3

1621

Q12873
IEPGMLIEGPPGPEG

COL5A1

461

P20908
IPGMIYEDLEGPEPP

CEP192

236

Q8TEP8
TYSMEGPPEDPGIVP

KIFC2

491

Q96AC6
TGRPYPGMEPPGPQE

RTEL1

1136

Q9NZ71
VSDYAGPPEPPAGPM

SOX17

256

Q9H6I2
DGMPVGPVPPGFFQP

SSBP2

111

P81877
IDPPRGVLMYGPPGC

PSMC4

196

P43686
MIYGDPPPEVIGIPL

SCN4A

66

P35499
KAGYITPVPGGVGPM

MTHFD2

301

P13995
LGGYSPPPEEAMPFE

GNAS

151

Q5JWF2
GMGIPVLPYPEPAEP

IGSF9B

1141

Q9UPX0
VMPRVSIPPYPIAGG

STIM2

466

Q9P246
MGEPEPPGPDVYQLA

ZNF710

56

Q8N1W2
YPMPQDFVPGPEAGQ

TEX13C

156

A0A0J9YWL9
YEGMGPVLAPVTPVP

RBPJ

341

Q06330
MAGGVDGPIGIPFPD

ZBTB7A

1

O95365