Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H2B deubiquitinase activity

USP49 USP22

1.22e-054292GO:0140936
GeneOntologyMolecularFunctionhistone deubiquitinase activity

USP49 USP22

5.67e-058292GO:0140934
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP44 USP49 USP22

5.94e-04114293GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP44 USP49 USP22

7.59e-04124293GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP44 USP49 USP22

1.01e-03137293GO:0019783
GeneOntologyMolecularFunctionphosphoprotein phosphatase activity

PTPN9 PPP3CA PTPRA

2.54e-03189293GO:0004721
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP44 USP49 USP22

2.66e-03192293GO:0008234
Domainzf-UBP

USP44 USP49 USP22

1.21e-0614293PF02148
DomainZF_UBP

USP44 USP49 USP22

1.21e-0614293PS50271
DomainZnf_UBP

USP44 USP49 USP22

1.21e-0614293IPR001607
DomainCalx_beta

FRAS1 ITGB4

6.48e-058292SM00237
DomainCalx_beta

FRAS1 ITGB4

8.32e-059292IPR003644
DomainCalx-beta

FRAS1 ITGB4

8.32e-059292PF03160
DomainZnF_UBP

USP44 USP49

1.27e-0411292SM00290
DomainUSP_CS

USP44 USP49 USP22

1.44e-0466293IPR018200
DomainUSP_1

USP44 USP49 USP22

1.72e-0470293PS00972
DomainUCH

USP44 USP49 USP22

1.79e-0471293PF00443
DomainUSP_2

USP44 USP49 USP22

1.79e-0471293PS00973
DomainUSP_3

USP44 USP49 USP22

1.87e-0472293PS50235
DomainUSP_dom

USP44 USP49 USP22

1.87e-0472293IPR028889
DomainPeptidase_C19_UCH

USP44 USP49 USP22

1.87e-0472293IPR001394
DomainVWC_out

FRAS1 JAG1

3.92e-0419292SM00215
DomainZnF_U1

ZFHX2 ZNF407

9.21e-0429292SM00451
DomainZnf_U1

ZFHX2 ZNF407

9.21e-0429292IPR003604
DomainPTPc

PTPN9 PTPRA

1.42e-0336292SM00194
DomainVWC

FRAS1 JAG1

1.58e-0338292SM00214
DomainTYR_PHOSPHATASE_PTP

PTPN9 PTPRA

1.66e-0339292PS50055
DomainGrowth_fac_rcpt_

FRAS1 JAG1 LRP8

1.78e-03156293IPR009030
DomainPTPase_domain

PTPN9 PTPRA

1.84e-0341292IPR000242
DomainY_phosphatase

PTPN9 PTPRA

1.84e-0341292PF00102
DomainVWF_dom

FRAS1 JAG1

1.93e-0342292IPR001007
DomainPTPc_motif

PTPN9 PTPRA

3.77e-0359292SM00404
DomainTyr_Pase_cat

PTPN9 PTPRA

3.77e-0359292IPR003595
DomainEGF_extracell

ITGB4 JAG1

3.90e-0360292IPR013111
DomainEGF_2

ITGB4 JAG1

3.90e-0360292PF07974
DomainLIM

PXN LPP

5.12e-0369292PF00412
Domain-

PXN LPP

5.27e-03702922.10.110.10
DomainLIM_DOMAIN_2

PXN LPP

5.41e-0371292PS50023
DomainZnf_LIM

PXN LPP

5.41e-0371292IPR001781
DomainLIM_DOMAIN_1

PXN LPP

5.41e-0371292PS00478
DomainLIM

PXN LPP

5.41e-0371292SM00132
DomainEGF

FRAS1 JAG1 LRP8

5.64e-03235293SM00181
DomainTyr_Pase_AS

PTPN9 PTPRA

5.71e-0373292IPR016130
DomainEGF-like_dom

FRAS1 JAG1 LRP8

6.62e-03249293IPR000742
DomainEGF_1

ITGB4 JAG1 LRP8

7.07e-03255293PS00022
DomainEGF-like_CS

ITGB4 JAG1 LRP8

7.54e-03261293IPR013032
DomainTYR_PHOSPHATASE_1

PTPN9 PTPRA

7.85e-0386292PS00383
DomainEGF_CA

JAG1 LRP8

7.85e-0386292PF07645
DomainEGF_2

ITGB4 JAG1 LRP8

7.86e-03265293PS01186
DomainTYR_PHOSPHATASE_2

PTPN9 PTPRA

8.03e-0387292PS50056
DomainTYR_PHOSPHATASE_dom

PTPN9 PTPRA

8.03e-0387292IPR000387
Domain-

PTPN9 PTPRA

8.94e-03922923.90.190.10
DomainEGF_Ca-bd_CS

JAG1 LRP8

9.89e-0397292IPR018097
DomainEGF_CA

JAG1 LRP8

1.03e-0299292PS01187
DomainProt-tyrosine_phosphatase-like

PTPN9 PTPRA

1.03e-0299292IPR029021
DomainASX_HYDROXYL

JAG1 LRP8

1.05e-02100292PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG1 LRP8

1.17e-02106292IPR000152
Pubmed

ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.

USP44 USP49 USP22

4.36e-08929329669287
Pubmed

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.

PXN PTPRA ITGB4 LPP

4.55e-077529415951569
Pubmed

METTL3-mediated m6A modification is required for cerebellar development.

DAPK1 JAG1 LRP8

6.86e-072129329879109
Pubmed

Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation.

PXN ST6GAL1

4.02e-06429220127017
Pubmed

USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA.

USP49 USP22

4.41e-051229227801882
Pubmed

Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling.

DAPK1 JAG1

8.00e-051629216061358
Pubmed

Sall4 regulates cell fate decision in fetal hepatic stem/progenitor cells.

ITGB4 JAG1

8.00e-051629219185577
Pubmed

Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.

ITGB4 JAG1

8.00e-051629217021047
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

PTPRA ITGB4 LRP8

8.22e-0510129323382219
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPN9 PTPRA

9.06e-051729219727691
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

DAPK1 PTPRA CAMSAP1 JAG1 LRP8

9.88e-0556929530639242
Pubmed

Assessment of Alzheimer's disease case-control associations using family-based methods.

PGBD1 DAPK1

1.53e-042229218830724
Pubmed

Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases.

USP44 USP49

1.68e-042329214715245
Pubmed

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

ITGB4 JAG1

2.15e-042629225446530
Pubmed

Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.

PGBD1 DAPK1

2.50e-042829220534741
Pubmed

The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.

DAPK1 ITGB4

2.69e-042929219094228
Pubmed

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

ITGB4 JAG1

3.08e-043129222274697
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

PXN DAPK1 ITGB4 DHX9

3.29e-0440129425852190
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

FRAS1 ZNF148

6.21e-044429227505670
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

PPP3CA CAMSAP1 LPP

6.97e-0420929336779422
Pubmed

Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PXN PTPN9

7.09e-044729219167335
Pubmed

Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.

PXN JAG1

7.39e-044829228924218
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

CAMSAP1 TAX1BP1 LPP

7.87e-0421829333378226
InteractionARPC1A interactions

DAPK1 ACTR3B USP22 TAX1BP1

1.33e-05102294int:ARPC1A
InteractionARPC5 interactions

DAPK1 ACTR3B USP22 TAX1BP1

1.80e-05110294int:ARPC5
CytobandEnsembl 112 genes in cytogenetic band chr3q27

ST6GAL1 LPP

2.98e-03128292chr3q27
Cytoband17p11.2

B9D1 USP22

4.55e-0315929217p11.2
GeneFamilyUbiquitin specific peptidases

USP44 USP49 USP22

3.60e-0556213366
GeneFamilyLIM domain containing

PXN LPP

2.11e-03592121218
CoexpressionSESTO_RESPONSE_TO_UV_C5

ZNF148 ITGB4 JAG1

1.79e-0546293M1470
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN

USP44 PTPRA ZNF148 DHX9

2.89e-05161294M8250
CoexpressionWU_CELL_MIGRATION

DAPK1 ITGB4 JAG1 SLC27A2

4.76e-05183294M2001
CoexpressionROZANOV_MMP14_CORRELATED

DAPK1 JAG1

6.46e-0511292M2987
CoexpressionWHITESIDE_CISPLATIN_RESISTANCE_UP

PXN ITGB4

6.46e-0511292M1499
CoexpressionADDYA_ERYTHROID_DIFFERENTIATION_BY_HEMIN

TAX1BP1 SLC27A2 DHX9

7.49e-0574293M11516
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 CRISP1 ITGB4 JAG1

3.25e-06158294d78e7e52657dc094430291fec07e9c298be9e584
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

USP44 DAPK1 FRAS1 FRMD3

3.86e-06165294f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DAPK1 JAG1 FRMD3 SLC27A2

5.21e-06178294c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TM6SF2 ITGB4 JAG1 FRMD3

5.21e-061782949f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

JAG1 FRMD3 LPP

1.51e-0416029329c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

FRAS1 PPP3CA ACTR3B

1.53e-04161293ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB4 JAG1 LRP8

1.65e-04165293936581de8fcd097401707438b9bbe89dd4e3e247
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231|Adult / Lineage, Cell type, age group and donor

USP44 DAPK1 FRAS1

1.80e-04170293269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP49 ACTR3B LRP8

1.83e-041712932dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP49 ACTR3B LRP8

1.83e-041712932aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGB4 JAG1 FRMD3

1.90e-04173293b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCelldroplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP49 ACTR3B LRP8

1.90e-041732938fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCelldroplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP49 ACTR3B LRP8

1.90e-04173293f663571aaae2365660a8b526c355f4bd1a124a74
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ST6GAL1 ITGB4 JAG1

1.96e-041752932e54961846c65b185d9bd6e305dd81205579d890
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 TM6SF2 SLC27A2

1.96e-041752935c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ST6GAL1 ITGB4 JAG1

1.96e-04175293efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGB4 JAG1 FRMD3

2.00e-0417629327e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGB4 JAG1 FRMD3

2.00e-04176293d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JAG1 FRMD3 LPP

2.03e-04177293a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JAG1 FRMD3 LPP

2.03e-041772933645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGB4 JAG1 FRMD3

2.03e-04177293d68132e145bd413404fdbe215b5dbe520e756e50
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM6SF2 ITGB4 JAG1

2.06e-041782935cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCellfacs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM6SF2 ITGB4 JAG1

2.06e-04178293f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

USP44 DAPK1 FRAS1

2.10e-04179293cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

JAG1 FRMD3 LPP

2.17e-041812938dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TM6SF2 ITGB4 JAG1

2.20e-04182293ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TM6SF2 ITGB4 JAG1

2.20e-0418229347ff6b4002a4167412c79210651316d1342503f9
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

JAG1 FRMD3 LPP

2.24e-04183293e3835db4795362b0442d5893baf2a78efcc20428
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

JAG1 FRMD3 LPP

2.31e-04185293ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB4 JAG1 FRMD3

2.31e-04185293f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX2 DAPK1 LRP8

2.31e-0418529348de4d9fad55077732bf64eca4919103ecbc1512
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

JAG1 FRMD3 LPP

2.31e-04185293acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellNasal_Brush-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

B9D1 PXN JAG1

2.35e-04186293f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGB4 JAG1 FRMD3

2.35e-04186293ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGB4 JAG1 FRMD3

2.35e-04186293ed924852cd7132c8f6703522037dc22bd2c83193
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB4 JAG1 FRMD3

2.35e-041862931e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM6SF2 ITGB4 JAG1

2.35e-041862935302399825f213d105ac70b91366a4513b732838
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TM6SF2 ITGB4 FRMD3

2.35e-04186293c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TM6SF2 JAG1 FRMD3

2.42e-0418829359f276e23c8380bae57d7ecca3a8b83df4bc150b
ToppCellEndothelial-Endothelial-E|Endothelial / shred on cell class and cell subclass (v4)

ITGB4 JAG1 FRMD3

2.42e-041882932777eb7689b271c199021fe7d9db88ccebff14de
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.46e-0418929306c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

PGBD1 USP22 SLC27A2

2.50e-04190293e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGB4 JAG1 FRMD3

2.50e-04190293d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGB4 JAG1 FRMD3

2.50e-041902933cf464664d6aa22b212e60b70885953887e92483
ToppCelldroplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITGB4 JAG1 FRMD3

2.50e-041902933b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.54e-04191293de54dab85db70f847de75b3b6d7667a0e13b9bfb
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF148 TAX1BP1 LPP

2.54e-0419129309db184cb90fe282a14474d7217068c58092c6f8
ToppCellP03-Endothelial-large_vessel_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ITGB4 JAG1 FRMD3

2.54e-04191293b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCellCOVID-19-Heart-EC_(POSTN)|Heart / Disease (COVID-19 only), tissue and cell type

DAPK1 ST6GAL1 ITGB4

2.58e-04192293c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGB4 JAG1 FRMD3

2.58e-04192293285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.58e-04192293dc40ef2341e5d6a6d479f140e023fe1bf687928d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-04193293d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-041932938b77625bf3c87d39767fb391d1beaca4ab02342b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-041932932c15186d15545804cc262da9137ab825609d4b2c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-04193293010717ca052b6c8a525a43aaeffddea0d1113e63
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-041932933ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-041932932189da4b727e25e62669d7b9257f06493be21a27
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.62e-04193293658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.66e-041942931bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DAPK1 FRMD3 LRP8

2.66e-0419429383863da11dfbe59b2d0a2c08db40b537c150588c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ST6GAL1 ITGB4

2.74e-041962937d5eaed189aa6116f3799be010139fb675ec65e0
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX2 ST6GAL1 ITGB4

2.74e-04196293dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-04200293858421b91f5207b7934b5c219752cb9322a3da31
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-04200293347a510755374c6a66acee326565dfc447993f18
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

FRAS1 ITGB4 JAG1

2.90e-0420029307d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCellSepsis-ICU-SEP-Lymphocyte-T/NK-dn_T|ICU-SEP / Disease, condition lineage and cell class

B9D1 USP49 ACTR3B

2.90e-042002939ee3e18dc429b9c472e3e366d9bfdbb150daa369
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-042002938d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-042002936a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 TM6SF2 JAG1

2.90e-04200293ad3fb8ef0be45032369d1325024787fbe1dfb8d6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial|10w / Sample Type, Dataset, Time_group, and Cell type.

FRAS1 ITGB4 JAG1

2.90e-04200293ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-04200293cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-04200293a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

DAPK1 FRMD3 LRP8

2.90e-042002932131c8e7fa054b79906eaf60536da892438b09cd
Drug0316684-0000 [391209-55-5]; Down 200; 10uM; MCF7; HT_HG-U133A

B9D1 PXN PTPRA ITGB4 DHX9

4.18e-061932957052_DN
DrugCapsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A

PXN ZNF407 CAMSAP1 CRISP1 JAG1

4.40e-061952955673_UP
DrugAC1L9DEQ

JAG1 LPP

4.70e-063292CID000442786
DrugPuromycin dihydrochloride [58-58-2]; Down 200; 7.4uM; PC3; HT_HG-U133A

B9D1 PXN DHX9 LRP8

8.55e-051852946711_DN
Drug0316684-0000 [391209-55-5]; Up 200; 10uM; PC3; HT_HG-U133A

B9D1 PXN ITGB4 DHX9

1.01e-041932947098_UP
DrugConessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A

FRAS1 CAMSAP1 ITGB4 LPP

1.03e-041942942792_DN
Drug16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; PC3; HT_HG-U133A

B9D1 PXN JAG1 TAX1BP1

1.05e-041952947509_DN
DrugPyrimethamine [58-14-0]; Up 200; 16uM; HL60; HG-U133A

DAPK1 PTPRA JAG1 FBXL5

1.05e-041952941974_UP
Drugbenserazide hydrochloride; Down 200; 10uM; SKMEL5; HG-U133A

B9D1 PPP3CA PTPRA JAG1

1.07e-04196294631_DN
DrugHarmol hydrochloride monohydrate [40580-83-4]; Down 200; 15.8uM; PC3; HT_HG-U133A

B9D1 PXN PTPRA ITGB4

1.07e-041962947320_DN
DrugMidodrine hydrochloride [3092-17-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A

PXN ZFHX2 ZNF407 FRAS1

1.07e-041962942250_UP
DrugBemegride [64-65-3]; Down 200; 25.8uM; MCF7; HT_HG-U133A

PXN CAMSAP1 ITGB4 JAG1

1.07e-041962943389_DN
DrugDipyridamole [58-32-2]; Up 200; 8uM; MCF7; HT_HG-U133A

B9D1 ZFHX2 DAPK1 CAMSAP1

1.09e-041972945252_UP
DrugRepaglinide [135062-02-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

PXN ACTR3B ITGB4 FBXL5

1.11e-041982947216_DN
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A_EA

ZFHX2 PTPRA JAG1 LPP

1.11e-041982941002_UP
DrugErythromycin [114-07-8]; Down 200; 5.4uM; MCF7; HT_HG-U133A

PXN PTPN9 ITGB4 JAG1

1.11e-041982941510_DN
DrugOxantel pamoate [68813-55-8]; Up 200; 6.6uM; HL60; HT_HG-U133A

B9D1 PTPRA CAMSAP1 LPP

1.13e-041992941277_UP
DrugAtropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A

B9D1 PXN TAX1BP1 FBXL5

1.13e-041992947219_DN
DrugFluticasone propionate [80474-14-2]; Up 200; 8uM; MCF7; HT_HG-U133A

B9D1 PXN CAMSAP1 ITGB4

1.13e-041992947348_UP
DrugTrazodone hydrochloride [25332-39-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A

PXN PTPRA CAMSAP1 ITGB4

1.16e-042002947410_DN
DiseaseMalignant neoplasm of salivary gland

DAPK1 ITGB4 JAG1

1.18e-0545293C0220636
DiseaseSalivary Gland Neoplasms

DAPK1 ITGB4 JAG1

1.34e-0547293C0036095
DiseaseAdenoid Cystic Carcinoma

DAPK1 ITGB4 JAG1

1.29e-04100293C0010606
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

DAPK1 CAMSAP1 LPP

2.87e-04131293C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

DAPK1 CAMSAP1 LPP

2.87e-04131293C4552091
DiseaseJuvenile arthritis

DAPK1 CAMSAP1 LPP

2.87e-04131293C3495559
DiseaseJuvenile psoriatic arthritis

DAPK1 CAMSAP1 LPP

2.87e-04131293C3714758
DiseaseJuvenile-Onset Still Disease

DAPK1 CAMSAP1 LPP

3.14e-04135293C0087031
DiseaseNon-Small Cell Lung Carcinoma

PXN DAPK1 ITGB4

4.79e-04156293C0007131
Diseaseliver fat measurement

ZFHX2 TM6SF2

8.21e-0443292EFO_0010821
Diseasehemoglobin A1 measurement

ST6GAL1 PTPN9 PTPRA JAG1

1.60e-03520294EFO_0007629
Diseasephosphatidylcholine measurement

ACTR3B TM6SF2 FRMD3

2.68e-03284293EFO_0010226
Diseaseage of onset of asthma

PTPRA LPP

2.74e-0379292OBA_2001001
Diseasereticulocyte count

USP49 ST6GAL1 KLHL10 PTPRA JAG1

3.23e-031045295EFO_0007986

Protein segments in the cluster

PeptideGeneStartEntry
GNPVYFCCYDYFAAN

DAPK1

816

P53355
YCYICPDIVKEFAKY

ACTR3B

231

Q9P1U1
CQFRALYCYYPDTEE

CAMSAP1

1521

Q5T5Y3
LCTNPCIYYDEYFDC

CRISP1

206

P54107
PEQYYFCYKAILEFA

PTPN9

561

P43378
ECQYESCAPQYYLDF

FRAS1

936

Q86XX4
FYAVEKKAYCEPCYI

LPP

456

Q93052
LYPYCDYEMKVCAYG

ITGB4

1186

P16144
EKDYHNLFSPRCYYC

PXN

406

P49023
PEFEQFHYEYYCPLK

FRMD3

566

A2A2Y4
CIGICKFTDYYYCPE

KLHL10

141

Q6JEL2
CPSLNDEYFYYCDNI

FBXL5

651

Q9UKA1
QFPEYDDLYCKYCFV

B9D1

21

Q9UPM9
CSYFYSYPAVCEFLQ

PPP3CA

256

Q08209
FCEYFFNCPIIEVYG

DHX9

551

Q08211
YFKCECYPGYEMDLL

LRP8

396

Q14114
YEFCYKVVQEYIDAF

PTPRA

781

P18433
YNRASDYFCKCPEDY

JAG1

541

P78504
YLPNDDGEFYQFCYV

TAX1BP1

91

Q86VP1
LCCPYFFQDIGYFLK

SLC27A2

21

O14975
DVCYYYQKFFDSACT

ST6GAL1

351

P15907
YAPLEEYYCFDKSMC

PGBD1

536

Q96JS3
YCFLCQDYIYDKDME

USP22

111

Q9UPT9
TDCPYCDVKYDFYVS

ZFHX2

2146

Q9C0A1
DLYVFCYLCKDYVLN

USP49

71

Q70CQ1
DCPTDACFVYIYQYE

TM6SF2

241

Q9BZW4
GEKPYQCEYCLQYFS

ZNF148

251

Q9UQR1
TKEFEFYCMACDYYA

ZNF407

1041

Q9C0G0
YVFCYLCDDYVLNDN

USP44

76

Q9H0E7