Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of skin epidermis	KRT6A KRT6B KRT75 KRT6C	4.54e-05	43	92	4	GO:0030280
GeneOntologyMolecularFunction	microtubule plus-end binding	CKAP5 APC DST	1.37e-04	22	92	3	GO:0051010
GeneOntologyCellularComponent	Golgi cis cisterna	GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	1.48e-05	33	95	4	GO:0000137
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	WHRN KRT6A KRT6B CKAP5 AKNA APC TOGARAM1 SPECC1 GOLGA8N DST KRT75 KRT6C GOLGA8O	2.11e-04	899	95	13	GO:0099513
GeneOntologyCellularComponent	cis-Golgi network	GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	6.12e-04	85	95	4	GO:0005801
GeneOntologyCellularComponent	supramolecular fiber	WHRN KRT6A KRT6B CKAP5 AKNA APC MYOZ3 TOGARAM1 SPECC1 GOLGA8N DST KRT75 KRT6C GOLGA8O	8.62e-04	1179	95	14	GO:0099512
GeneOntologyCellularComponent	Golgi cisterna membrane	GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	8.93e-04	94	95	4	GO:0032580
GeneOntologyCellularComponent	supramolecular polymer	WHRN KRT6A KRT6B CKAP5 AKNA APC MYOZ3 TOGARAM1 SPECC1 GOLGA8N DST KRT75 KRT6C GOLGA8O	9.20e-04	1187	95	14	GO:0099081
GeneOntologyCellularComponent	keratin filament	KRT6A KRT6B KRT75 KRT6C	1.00e-03	97	95	4	GO:0045095
Domain	Keratin_2_head	KRT6A KRT6B KRT75 KRT6C	5.43e-06	24	92	4	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT75 KRT6C	5.43e-06	24	92	4	PF16208
Domain	Keratin_II	KRT6A KRT6B KRT75 KRT6C	7.59e-06	26	92	4	IPR003054
Domain	VWD	MUC19 MUC5B MUC4	6.18e-05	16	92	3	SM00216
Domain	VWF_type-D	MUC19 MUC5B MUC4	6.18e-05	16	92	3	IPR001846
Domain	VWFD	MUC19 MUC5B MUC4	6.18e-05	16	92	3	PS51233
Domain	VWD	MUC19 MUC5B MUC4	6.18e-05	16	92	3	PF00094
Domain	Elf-1_N	ELF1 ELF4	7.18e-05	3	92	2	PF12310
Domain	TF_Elf_N	ELF1 ELF4	7.18e-05	3	92	2	IPR022084
Domain	GOLGA2L5	GOLGA8R GOLGA8N GOLGA8O	8.95e-05	18	92	3	PF15070
Domain	Golgin_A	GOLGA8R GOLGA8N GOLGA8O	8.95e-05	18	92	3	IPR024858
Domain	Intermediate_filament_CS	KRT6A KRT6B KRT75 KRT6C	2.63e-04	63	92	4	IPR018039
Domain	Filament	KRT6A KRT6B KRT75 KRT6C	4.16e-04	71	92	4	SM01391
Domain	IF	KRT6A KRT6B KRT75 KRT6C	4.39e-04	72	92	4	PS00226
Domain	Filament	KRT6A KRT6B KRT75 KRT6C	4.63e-04	73	92	4	PF00038
Domain	DIX	DVL1P1 DIXDC1	4.96e-04	7	92	2	PF00778
Domain	DIX	DVL1P1 DIXDC1	4.96e-04	7	92	2	IPR001158
Domain	DIX	DVL1P1 DIXDC1	4.96e-04	7	92	2	PS50841
Domain	DAX	DVL1P1 DIXDC1	4.96e-04	7	92	2	SM00021
Domain	IF	KRT6A KRT6B KRT75 KRT6C	5.39e-04	76	92	4	IPR001664
Domain	TIL	MUC19 MUC5B	1.53e-03	12	92	2	PF01826
Domain	C8	MUC19 MUC5B	1.53e-03	12	92	2	PF08742
Domain	Unchr_dom_Cys-rich	MUC19 MUC5B	1.81e-03	13	92	2	IPR014853
Domain	C8	MUC19 MUC5B	1.81e-03	13	92	2	SM00832
Domain	TIL_dom	MUC19 MUC5B	2.10e-03	14	92	2	IPR002919
Domain	Sec7	PSD ARFGEF3	2.75e-03	16	92	2	SM00222
Domain	SEC7	PSD ARFGEF3	2.75e-03	16	92	2	PS50190
Domain	Sec7_dom	PSD ARFGEF3	2.75e-03	16	92	2	IPR000904
Domain	HEAT_type_2	CKAP5 PPP4R4	3.11e-03	17	92	2	IPR021133
Domain	CTCK_1	MUC19 MUC5B	3.49e-03	18	92	2	PS01185
Domain	VWC_out	MUC19 MUC5B	3.89e-03	19	92	2	SM00215
Domain	BRCT	MCPH1 DBF4	3.89e-03	19	92	2	PF00533
Domain	CH	SPECC1 DST DIXDC1	4.05e-03	65	92	3	SM00033
Domain	CH	SPECC1 DST DIXDC1	4.99e-03	70	92	3	PF00307
Domain	HEAT_REPEAT	CKAP5 TOGARAM1 PPP4R4	4.99e-03	70	92	3	PS50077
Domain	-	SPECC1 DST DIXDC1	5.19e-03	71	92	3	1.10.418.10
Domain	CT	MUC19 MUC5B	5.20e-03	22	92	2	SM00041
Domain	BRCT	MCPH1 DBF4	5.20e-03	22	92	2	SM00292
Domain	CH	SPECC1 DST DIXDC1	5.61e-03	73	92	3	PS50021
Domain	-	MCPH1 DBF4	5.68e-03	23	92	2	3.40.50.10190
Domain	CH-domain	SPECC1 DST DIXDC1	6.05e-03	75	92	3	IPR001715
Domain	Cys_knot_C	MUC19 MUC5B	6.69e-03	25	92	2	IPR006207
Domain	CTCK_2	MUC19 MUC5B	6.69e-03	25	92	2	PS01225
Domain	BRCT	MCPH1 DBF4	7.22e-03	26	92	2	PS50172
Domain	ETS_DOMAIN_1	ELF1 ELF4	8.35e-03	28	92	2	PS00345
Domain	ETS_DOMAIN_2	ELF1 ELF4	8.35e-03	28	92	2	PS00346
Domain	ETS	ELF1 ELF4	8.35e-03	28	92	2	SM00413
Domain	Ets_dom	ELF1 ELF4	8.35e-03	28	92	2	IPR000418
Domain	ETS_DOMAIN_3	ELF1 ELF4	8.35e-03	28	92	2	PS50061
Domain	Ets	ELF1 ELF4	8.35e-03	28	92	2	PF00178
Domain	BRCT_dom	MCPH1 DBF4	8.35e-03	28	92	2	IPR001357
Domain	EF-hand_7	DST CABP4 CALML4	8.54e-03	85	92	3	PF13499
Pathway	REACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC	MUC5B MUC12 MUC4	5.50e-05	16	67	3	M27410
Pathway	REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS	MUC5B MUC12 MUC4	6.65e-05	17	67	3	M27412
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC19 MUC5B MUC4	1.28e-04	21	67	3	MM15706
Pathway	REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	MUC5B MUC12 MUC4	1.70e-04	23	67	3	M556
Pathway	WP_15Q133_COPY_NUMBER_VARIATION_SYNDROME	GOLGA8R GOLGA8Q GOLGA8O	1.70e-04	23	67	3	M39883
Pathway	REACTOME_DECTIN_2_FAMILY	MUC5B MUC12 MUC4	2.47e-04	26	67	3	M27483
Pubmed	Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.	KRT6A KRT6B KRT75	2.17e-08	3	98	3	17170733
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	2.17e-08	3	98	3	29357356
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	2.17e-08	3	98	3	7543104
Pubmed	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.	KRT6A KRT6B KRT75	2.17e-08	3	98	3	17851587
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PRPF31 SRRM1 C19orf47 CKAP5 APC FAM117B LBR SPECC1 DENND2B DDX3X PPP4R4 ARFGEF3 DST CDC20	1.39e-07	861	98	14	36931259
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	PRPF31 SRRM1 KRT6A KRT6B C19orf47 DDX3X IGF2BP3 SAFB KRT6C GLYR1 ZNF638 SCAF11	1.44e-07	605	98	12	28977666
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC19 MUC5B MUC12 MUC4	1.76e-07	18	98	4	18834073
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PRPF31 SRRM1 KRT6A C19orf47 CKAP5 LBR SPECC1 DDX3X IGF2BP3 SAFB DST KRT6C UBR5 ZNF638 CKAP2L	1.83e-07	1024	98	15	24711643
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT6C	2.16e-07	5	98	3	20301457
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PRPF31 SRRM1 KRT6A HK1 MARK1 APC LBR DDX3X IGF2BP3 SAFB DST NRXN2 GLYR1 ZNF638 SEC61B	3.68e-07	1082	98	15	38697112
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	SRRM1 C19orf47 CKAP5 SPECC1 IGF2BP3 ZNF638 ELF1 ELF4 SCAF11	1.08e-06	370	98	9	22922362
Pubmed	Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development.	ILDR2 GOLGA8N CKAP2L GOLGA8O	1.33e-06	29	98	4	20568244
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	KRT6A ZFC3H1 DDX3X SAFB KRT75 ZNF638 SCAF11	1.78e-06	202	98	7	24639526
Pubmed	RIP4 regulates epidermal differentiation and cutaneous inflammation.	KRT6A KRT6B RIPK4	1.80e-06	9	98	3	19626033
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SRRM1 HK1 APC LBR PKHD1L1 DDX3X ARFGEF3 IGF2BP3 DST UBR5 AMOTL1 ZNF638	1.99e-06	777	98	12	35844135
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRPF31 SRRM1 MCPH1 CKAP5 LBR ZFC3H1 DDX3X SAFB DST NFIC GLYR1 ZNF638 SEC61B ELF4 SCAF11	3.38e-06	1294	98	15	30804502
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	PRPF31 KRT6A KRT6B LBR DDX3X IGF2BP3 GLYR1	6.34e-06	245	98	7	35652658
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	7.86e-06	2	98	2	11118885
Pubmed	DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants.	MARK1 DIXDC1	7.86e-06	2	98	2	27829159
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	7.86e-06	2	98	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	7.86e-06	2	98	2	10550545
Pubmed	Cloning of a novel human ELF-1-related ETS transcription factor, ELFR, its characterization and chromosomal assignment relative to ELF-1.	ELF1 ELF4	7.86e-06	2	98	2	9524226
Pubmed	Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.	APC AMER2	7.86e-06	2	98	2	22128170
Pubmed	Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).	APC ATOH1	7.86e-06	2	98	2	22586121
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	7.86e-06	2	98	2	9790766
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	7.86e-06	2	98	2	23662636
Pubmed	Period 2 mutation accelerates ApcMin/+ tumorigenesis.	APC PER2	7.86e-06	2	98	2	19010825
Pubmed	Depletion of transmembrane mucin 4 (Muc4) alters intestinal homeostasis in a genetically engineered mouse model of colorectal cancer.	APC MUC4	7.86e-06	2	98	2	35255004
Pubmed	Atonal homolog 1 is a tumor suppressor gene.	APC ATOH1	7.86e-06	2	98	2	19243219
Pubmed	Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the ApcMin model of colorectal cancer.	APC PACS2	7.86e-06	2	98	2	29312533
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	7.86e-06	2	98	2	11489919
Pubmed	Delayed wound healing in keratin 6a knockout mice.	KRT6A KRT6B	7.86e-06	2	98	2	10866680
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	7.86e-06	2	98	2	10953016
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	7.86e-06	2	98	2	6207530
Pubmed	Cytokeratins mediate epithelial innate defense through their antimicrobial properties.	KRT6A KRT6B	7.86e-06	2	98	2	23006328
Pubmed	Expression of mucins in mucoid otitis media.	MUC5B MUC4	7.86e-06	2	98	2	14690056
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	SRRM1 MARK1 APC ZFC3H1 SPECC1 IGF2BP3 AMOTL1 ZNF638	8.71e-06	361	98	8	30344098
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	SRRM1 CKAP5 TOGARAM1 LBR ZFC3H1 DDX3X ARFGEF3 SAFB	8.71e-06	361	98	8	26167880
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	MARK1 APC FAM117B DENND2B ZNF638	1.08e-05	102	98	5	15778465
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	PRPF31 KRT6A KRT6B CKAP5 ZFC3H1 SPECC1 DDX3X SAFB DST GLYR1 AMOTL1 ZNF638 SCAF11 CDC20	1.16e-05	1257	98	14	36526897
Pubmed	Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.	KRT6A KRT6B KRT75	1.18e-05	16	98	3	12399393
Pubmed	Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression.	PRPF31 RIPK4 CALML4	1.43e-05	17	98	3	12747765
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	SRRM1 DDX3X IGF2BP3 SAFB ZNF638	1.85e-05	114	98	5	31553912
Pubmed	Adenomatous polyposis coli (APC) is required for normal development of skin and thymus.	KRT6A KRT6B APC	2.03e-05	19	98	3	17002498
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WHRN CKAP5 PLEKHH1 ARFGEF3 PER2 UBR5 PACS2 RAB11FIP4	2.06e-05	407	98	8	12693553
Pubmed	RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.	KRT6A KRT6B KRT75 KRT6C	2.09e-05	57	98	4	31862882
Pubmed	Expression of mucin (MUC) genes in mucoepidermoid carcinoma.	MUC19 MUC4	2.35e-05	3	98	2	21072847
Pubmed	Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.	KRT6A KRT6B	2.35e-05	3	98	2	15601842
Pubmed	Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.	KRT6A KRT6B	2.35e-05	3	98	2	29587848
Pubmed	A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.	KRT6A KRT6B	2.35e-05	3	98	2	32213122
Pubmed	Amer2 protein interacts with EB1 protein and adenomatous polyposis coli (APC) and controls microtubule stability and cell migration.	APC AMER2	2.35e-05	3	98	2	22898821
Pubmed	A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.	KRT6A KRT6B	2.35e-05	3	98	2	14573483
Pubmed	Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair.	KRT6A KRT6B	2.35e-05	3	98	2	14568992
Pubmed	Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.	KRT6A KRT6B	2.35e-05	3	98	2	1713533
Pubmed	Putative tumor suppressor EDD interacts with and up-regulates APC.	APC UBR5	2.35e-05	3	98	2	18076571
Pubmed	The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.	KRT6A KRT6B GOLGA8N GOLGA8O	2.40e-05	59	98	4	26371508
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PRPF31 SRRM1 ZFC3H1 DDX3X IGF2BP3 SAFB NFIC GLYR1 ZNF638 SEC61B SCAF11	2.74e-05	847	98	11	35850772
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	ATG2B APC ARFGEF3 IGF2BP3 DST UBR5	2.91e-05	209	98	6	36779422
Pubmed	New consensus nomenclature for mammalian keratins.	KRT6A KRT6B KRT75 KRT6C	3.11e-05	63	98	4	16831889
Pubmed	Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.	PRPF31 SRRM1 KRT6A CKAP5 KRT6C GLYR1	4.08e-05	222	98	6	35941108
Pubmed	Wee1B, Myt1, and Cdc25 function in distinct compartments of the mouse oocyte to control meiotic resumption.	PDE3A WEE2	4.70e-05	4	98	2	20083600
Pubmed	Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion.	KRT6A KRT6B	4.70e-05	4	98	2	30389720
Pubmed	A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.	KRT6A KRT6B	4.70e-05	4	98	2	22264670
Pubmed	Mouse models in preclinical studies for pachyonychia congenita.	KRT6A KRT6B	4.70e-05	4	98	2	16250208
Pubmed	Conditional knockout of TOG results in CNS hypomyelination.	CKAP5 TOGARAM1	4.70e-05	4	98	2	28063167
Pubmed	Contribution of ATOH1+ Cells to the Homeostasis, Repair, and Tumorigenesis of the Colonic Epithelium.	APC ATOH1	4.70e-05	4	98	2	29233556
Pubmed	Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.	KRT6A KRT6C	4.70e-05	4	98	2	9054461
Pubmed	Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.	GOLGA8N ROBO2 GOLGA8O	5.38e-05	26	98	3	31138815
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	HK1 MARK1 ATG2B DCBLD1 LBR SPECC1 IGF2BP3 SEC61B	5.45e-05	467	98	8	30194290
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	SRRM1 PDE3A DDX3X IGF2BP3 DST KIAA1549L	5.47e-05	234	98	6	36243803
Pubmed	Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F.	KRT6A KRT6B DDX3X KRT6C	6.18e-05	75	98	4	31527668
Pubmed	Polymorphism of human mucin genes in chest disease: possible significance of MUC2.	MUC5B MUC4	7.82e-05	5	98	2	11062147
Pubmed	Role of ubiquitin-protein ligase UBR5 in the disassembly of mitotic checkpoint complexes.	UBR5 CDC20	7.82e-05	5	98	2	35217622
Pubmed	Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.	KRT6A KRT6B	7.82e-05	5	98	2	38693267
Pubmed	Role for keratins 6 and 17 during wound closure in embryonic mouse skin.	KRT6A KRT6B	7.82e-05	5	98	2	12557214
Pubmed	Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.	APC PER2	7.82e-05	5	98	2	19106159
Pubmed	Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12.	KRT6A KRT6B	7.82e-05	5	98	2	1713141
Pubmed	Proteomic and biochemical studies of calcium- and phosphorylation-dependent calmodulin complexes in Mammalian cells.	DDX3X UBR5	7.82e-05	5	98	2	17696464
Pubmed	The diagnostic utility of D2-40, calretinin, CK5/6, desmin and MOC-31 in the differentiation of mesothelioma from adenocarcinoma in pleural effusion cytology.	KRT6A KRT6B	7.82e-05	5	98	2	23075894
Pubmed	Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection.	APC ROBO2	7.82e-05	5	98	2	23903657
Pubmed	Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family.	APC CDC20	7.82e-05	5	98	2	9811605
Pubmed	Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells.	KRT6A KRT6B	7.82e-05	5	98	2	31898934
Pubmed	Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias.	ELF1 ELF4	7.82e-05	5	98	2	10207087
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SRRM1 HK1 CKAP5 IGF2BP3 DST UBR5 GLYR1 ZNF638 SCAF11	9.78e-05	653	98	9	22586326
Pubmed	An EB1-binding motif acts as a microtubule tip localization signal.	APC DST	1.17e-04	6	98	2	19632184
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC19 MUC5B	1.17e-04	6	98	2	19110483
Pubmed	Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse.	KRT6A KRT6B	1.17e-04	6	98	2	16239341
Pubmed	Isoforms of the Ets transcription factor NERF/ELF-2 physically interact with AML1 and mediate opposing effects on AML1-mediated transcription of the B cell-specific blk gene.	ELF1 ELF4	1.17e-04	6	98	2	14970218
Pubmed	Identification of functional variants for cleft lip with or without cleft palate in or near PAX7, FGFR2, and NOG by targeted sequencing of GWAS loci.	KRT6A KRT6B	1.17e-04	6	98	2	25704602
Pubmed	p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.	KRT6A KRT6B	1.17e-04	6	98	2	25383540
Pubmed	The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation.	APC CDC20	1.17e-04	6	98	2	9637688
Pubmed	Keratin 6 is not essential for mammary gland development.	KRT6A KRT6B	1.17e-04	6	98	2	16790075
Pubmed	Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.	GOLGA8N ATOH1 GOLGA8O	1.22e-04	34	98	3	23533177
Pubmed	TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.	KRT6A KRT6B DDX3X IGF2BP3	1.31e-04	91	98	4	34445801
Pubmed	EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole.	UBR5 CDC20	1.64e-04	7	98	2	25833949
Pubmed	Deciphering TGF-β3 function in medial edge epithelium specification and fusion during mouse secondary palate development.	KRT6A KRT6B	1.64e-04	7	98	2	25104574
Pubmed	Modeling of a human circadian mutation yields insights into clock regulation by PER2.	APC PER2	1.64e-04	7	98	2	17218255
Pubmed	Frizzled6 deficiency disrupts the differentiation process of nail development.	KRT6A KRT6B	1.64e-04	7	98	2	23439395
Pubmed	Prediction of local recurrence, distant metastases, and death after breast-conserving therapy in early-stage invasive breast cancer using a five-biomarker panel.	KRT6A KRT6B	1.64e-04	7	98	2	19720911
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PRPF31 SRRM1 KRT6A KRT6B CKAP5 DDX3X IGF2BP3 KRT75 KRT6C UBR5 NFIC ZNF638 SCAF11	1.71e-04	1415	98	13	28515276
Interaction	KRT17 interactions	CCNL2 KRT6A KRT6B APC DDX3X IGF2BP3 DST KRT75 PER2 KRT6C ATOH1	4.04e-08	252	98	11	int:KRT17
Interaction	KRT36 interactions	KRT6A KRT6B MYOZ3 PLEKHN1 KRT75 KRT6C	1.61e-06	74	98	6	int:KRT36
Interaction	PHTF1 interactions	KRT6A KRT6B KRT75 KRT6C	2.40e-06	20	98	4	int:PHTF1
Interaction	YWHAH interactions	SRRM1 MARK1 C19orf47 CKAP5 APC FAM117B RIPK4 LBR SPECC1 DENND2B DDX3X PPP4R4 ARFGEF3 DST ZNF638 PACS2 CDC20	2.12e-05	1102	98	17	int:YWHAH
Interaction	KRT13 interactions	KRT6A KRT6B APC DDX3X KRT75 KRT6C	2.18e-05	116	98	6	int:KRT13
Interaction	KRT26 interactions	KRT6A KRT6B KRT75 KRT6C	2.45e-05	35	98	4	int:KRT26
Interaction	KRT25 interactions	KRT6A KRT6B KRT75 KRT6C	2.45e-05	35	98	4	int:KRT25
Interaction	KRT15 interactions	PRPF31 KRT6A KRT6B APC KRT75 KRT6C ZNF638	2.62e-05	178	98	7	int:KRT15
Interaction	ANAPC15 interactions	CCNL2 ZFC3H1 SAFB PACS2 SCAF11 CDC20	3.81e-05	128	98	6	int:ANAPC15
Interaction	KRT14 interactions	KRT6A KRT6B APC DDX3X DST KRT75 KRT6C	4.25e-05	192	98	7	int:KRT14
Interaction	KRT5 interactions	KRT6A KRT6B APC DDX3X DST KRT75 KRT6C	4.39e-05	193	98	7	int:KRT5
Interaction	PPP1CC interactions	SRRM1 MARK1 APC LBR ZFC3H1 PPP1R15A SPECC1 DDX3X IGF2BP3 UBR5 AMOTL1 ZNF638 SLX4	5.85e-05	738	98	13	int:PPP1CC
Interaction	YWHAZ interactions	PRPF31 KRT6B MARK1 CKAP5 APC COP1 FAM117B RIPK4 LBR SPECC1 DENND2B PPP4R4 DST PER2 AMOTL1 ZNF638 PACS2 SCAF11	5.92e-05	1319	98	18	int:YWHAZ
Interaction	PCID2 interactions	CCNL2 COP1 ZFC3H1 DDX3X UBR5	8.63e-05	92	98	5	int:PCID2
Interaction	KRT84 interactions	KRT6A KRT6B KRT75 KRT6C	9.42e-05	49	98	4	int:KRT84
Interaction	YWHAG interactions	SRRM1 MARK1 C19orf47 CKAP5 APC FAM117B RIPK4 LBR SPECC1 DENND2B DDX3X PPP4R4 DST ZNF638 PACS2 SCAF11 CDC20	1.00e-04	1248	98	17	int:YWHAG
Interaction	YWHAE interactions	PRPF31 MARK1 CKAP5 APC FAM117B RIPK4 LBR SPECC1 DENND2B PPP4R4 IGF2BP3 DST PER2 AMOTL1 ZNF638 PACS2 SCAF11	1.08e-04	1256	98	17	int:YWHAE
Interaction	KRT37 interactions	KRT6B APC SPECC1 KRT75 KRT6C	1.28e-04	100	98	5	int:KRT37
Interaction	KRT6A interactions	KRT6A KRT6B DDX3X KRT75 PER2 KRT6C	1.31e-04	160	98	6	int:KRT6A
Interaction	EFNA1 interactions	KRT6A KRT6B TOGARAM1 DDX3X KRT6C	1.47e-04	103	98	5	int:EFNA1
Interaction	KRT35 interactions	PRPF31 KRT6A KRT6B KRT75 KRT6C	2.09e-04	111	98	5	int:KRT35
Interaction	KRT12 interactions	KRT6A KRT6B KRT75	2.10e-04	24	98	3	int:KRT12
Cytoband	Ensembl 112 genes in cytogenetic band chr15q13	GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	6.54e-05	100	98	4	chr15q13
Cytoband	12q13.13	KRT6A KRT6B KRT6C	4.09e-04	67	98	3	12q13.13
Cytoband	15q13.2	GOLGA8Q GOLGA8N	9.22e-04	21	98	2	15q13.2
GeneFamily	CD molecules\|Mucins	MUC19 MUC5B MUC12 MUC4	5.48e-07	21	58	4	648
GeneFamily	Keratins, type II	KRT6A KRT6B KRT75 KRT6C	1.58e-06	27	58	4	609
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HNBML5	MARK1 MUC19 APC FAM117B ARFGEF3 HIVEP3 AMER2 NRXN2 ROBO2 RAB11FIP4 SRRM3	1.11e-06	465	96	11	M39066
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	TOGARAM1 ZFC3H1 IGF2BP3 DST PER2 UBR5 ZNF638 ELF1 SCAF11	1.62e-06	300	96	9	M8702
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	PSD MARK1 MUC19 APC FAM117B ARFGEF3 HIVEP3 AMER2 OLFM3 KIAA1549L NRXN2 CABP4 ROBO2 RAB11FIP4 FRMPD3 SRRM3	2.51e-06	1106	96	16	M39071
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_INTERM_NEUROENDOCRINE_CELL	PCSK1 PSD MARK1 ARFGEF3 HIVEP3 DST ROBO2 SRRM3	6.56e-06	268	96	8	M45696
Coexpression	GU_PDEF_TARGETS_DN	KRT6A KRT6B KRT75 KRT6C	1.40e-05	40	96	4	M10480
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_SMALL_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	PCSK1 PSD PCDHB10 PCDHB9 CKAP5 ARFGEF3 FSD1L DBF4 CKAP2L CDC20 SRRM3	3.95e-05	680	96	11	MM456
CoexpressionAtlas	cerebral cortex	PCSK1 ILDR2 PSD COL20A1 PCDHB10 PCDHB9 APC MAGEE1 PPP4R4 PLEKHH1 ARFGEF3 FSD1L AMER2 OLFM3 KIAA1549L NRXN2 ROBO2 RAB11FIP4 FRMPD3 SRRM3	3.49e-06	1428	94	20	cerebral cortex
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_1000_k-means-cluster#1	ILDR2 DDX3X PLEKHH1 DST KIAA1549L NRXN2 UBR5 ZNF638	1.98e-05	259	94	8	Facebase_RNAseq_e8.5_Floor Plate_1000_K1
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B LBR HHLA1 DBF4 FRMPD3 CDC20	2.93e-06	180	98	6	271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPK4 PPP1R15A PLEKHH1 ARFGEF3 SYTL5 CALML4	3.02e-06	181	98	6	c7a220891567c7539ad5a9ac9db375f0de08ea00
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT6B MUC5B IGF2BP3 CKAP2L CDC20 MUC4	3.32e-06	184	98	6	4b864c74e2cf7e58d6bd151f955c43d72f035d52
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APC PPP1R15A DDX3X ZNF638 ELF1 SCAF11	3.32e-06	184	98	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PSD MUC5B FSD1L DBF4 CKAP2L CDC20	3.43e-06	185	98	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT6B MUC5B IGF2BP3 CKAP2L CDC20 MUC4	3.43e-06	185	98	6	4d0f3d86fab02c80093e62cb0c79c586c13c5412
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT6A KRT6B MUC5B ARFGEF3 KRT6C MUC4	3.76e-06	188	98	6	07705bed928683470a52c8ccfa40ffb9a0971318
ToppCell	distal-1-Epithelial-Proliferating_Basal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B MARK1 IGF2BP3 KRT6C CDC20	5.21e-06	199	98	6	93450257180d918c310bca7b5defc74390c48091
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR2 MUC19 MUC5B PKHD1L1 KIAA1549L	2.78e-05	160	98	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ILDR2 MUC19 MUC5B PKHD1L1 KIAA1549L	2.78e-05	160	98	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	KRT6A KRT6B PPP1R15A PPP4R4 KRT6C	3.13e-05	164	98	5	de1646dbcf2a10b48e021acf7dc63e803e6a47ce
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 LBR DBF4 CKAP2L CDC20	3.41e-05	167	98	5	d21635df8b74189e3309eaf435af381fbe412574
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT6A KRT6B DST CKAP2L CDC20	3.51e-05	168	98	5	f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C19orf47 AKNA QRICH2 ROBO2 ELF4	3.61e-05	169	98	5	7cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 LBR DBF4 CKAP2L CDC20	3.61e-05	169	98	5	4db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCPH1 LBR DBF4 CKAP2L CDC20	3.71e-05	170	98	5	a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 PSD AMER2 NRXN2 SRRM3	4.15e-05	174	98	5	742c73c9e090848b464323cb17579b86658c6792
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 PSD AMER2 NRXN2 SRRM3	4.15e-05	174	98	5	7fed9722e64c60843092f2ba71256e3043011ef6
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC12 ARFGEF3 ATOH1 MUC4	4.26e-05	175	98	5	019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCell	PND07-Epithelial-Epithelial_Airway-Neurosecretory\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 MUC5B WEE2 SRRM3 FCAMR	4.26e-05	175	98	5	19eda8b5d39dc93d79737ebdbeeba5ec0cb23c51
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 LBR DBF4 CKAP2L CDC20	4.26e-05	175	98	5	9de288c338cee67be0e9b836c87799bbc1db1c38
ToppCell	droplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 PCSK1 PDE3A MARK1 SPECC1	4.50e-05	177	98	5	dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCell	5'-Adult-Distal_Rectal-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B MUC12 ARFGEF3 ATOH1 MUC4	4.62e-05	178	98	5	9099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCell	droplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 PCSK1 PDE3A MARK1 SPECC1	4.62e-05	178	98	5	416f85e51f45ec7949451fd47611a84e33e87245
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC5B PLEKHN1 PLEKHH1 PER2 MUC4	4.75e-05	179	98	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM1 PPP1R15A DDX3X ELF1 SCAF11	5.13e-05	182	98	5	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B IGF2BP3 KRT6C CDC20	5.13e-05	182	98	5	007fa56ed8b91f9af0df2114c00410b2f6cec8b6
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 MARK1 MYOZ3 PPP1R15A DENND2B	5.41e-05	184	98	5	94748f63947db79a6b4540e3090a63689fdd9452
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MUSTN1 MARK1 MYOZ3 PPP1R15A DENND2B	5.41e-05	184	98	5	819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 DBF4 CKAP2L ROBO2 CDC20	5.99e-05	188	98	5	95d0a796d62ce6d121e2028c378faffc14b35275
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PCSK1 ILDR2 PSD ARFGEF3 SRRM3	6.30e-05	190	98	5	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 LBR DBF4 CKAP2L CDC20	6.30e-05	190	98	5	4288189e3a499c395896c950598810b02f401685
ToppCell	3'_v3-Lung-Lymphocytic_NK-NK_CD56bright_CD16-\|Lung / Manually curated celltypes from each tissue	WHRN ILDR2 AKNA PPP1R15A DDX3X	6.45e-05	191	98	5	12ce360dc149c85d5a22cfc1bf53d54aef79edc1
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE3A PPP1R15A SPECC1 DST CALML4	6.45e-05	191	98	5	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l12-14\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LBR ARFGEF3 DBF4 CKAP2L CDC20	6.61e-05	192	98	5	52d0aa51e3b6ab3608a5f40bdde9f8134b3afd94
ToppCell	droplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CKAP5 LBR DBF4 CKAP2L CDC20	6.61e-05	192	98	5	96f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT6A KRT6B MUC5B IGF2BP3 MUC4	6.61e-05	192	98	5	612be3f861bd2f71a31c57f48c8b10930c3471ea
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KRT6A KRT6B MUC5B IGF2BP3 MUC4	6.61e-05	192	98	5	f627a3f43e2340c8ba502211940171f25c7ff436
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B ARFGEF3 SYTL5 ATOH1 MUC4	6.78e-05	193	98	5	402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 DBF4 CKAP2L ROBO2 CDC20	6.78e-05	193	98	5	a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B ARFGEF3 SYTL5 ATOH1 MUC4	6.78e-05	193	98	5	7ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLEKHH1 AMER2 DST PACS2 RAB11FIP4	6.78e-05	193	98	5	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LBR DBF4 CKAP2L SEC61B CDC20	6.78e-05	193	98	5	4a3e456f07e521519faeb9153e8d571cb8fbeaf9
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CKAP5 NRXN2 DBF4 CKAP2L CDC20	6.95e-05	194	98	5	7a66bd7d4fc9c6db861cedd2487f241e406869d1
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARFGEF3 DST SYTL5 ATOH1 MUC4	6.95e-05	194	98	5	49cc5f5de4380302100e8cd937f08abe317ac75e
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLEKHH1 ARFGEF3 AMER2 PACS2 DIXDC1	6.95e-05	194	98	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-goblet\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARFGEF3 DST SYTL5 ATOH1 MUC4	6.95e-05	194	98	5	fb935df966c451e659b8bde281f8aebcb632f6cf
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LBR DBF4 CKAP2L SEC61B CDC20	6.95e-05	194	98	5	5810d8e1f6b983bb346fe06dda22b8ba3f2144a6
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 ARFGEF3 DST ROBO2 MUC4	7.12e-05	195	98	5	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CKAP5 LBR DBF4 CKAP2L CDC20	7.12e-05	195	98	5	742c82c86487314cdb3178012004adb1164bcbdb
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC5B DENND2B PLEKHH1 ARFGEF3 MUC4	7.12e-05	195	98	5	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	COVID-19-kidney-TAL\|kidney / Disease (COVID-19 only), tissue and cell type	CASR AK3 ARFGEF3 HIVEP3 DST	7.29e-05	196	98	5	04f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B ARFGEF3 SYTL5 ATOH1 MUC4	7.29e-05	196	98	5	847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLEKHH1 ARFGEF3 AMER2 DST PACS2	7.47e-05	197	98	5	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 LBR DBF4 CKAP2L CDC20	7.47e-05	197	98	5	a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MUC5B ARFGEF3 SYTL5 ATOH1 MUC4	7.47e-05	197	98	5	d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT6A MARK1 CASR RIPK4 MUC4	7.47e-05	197	98	5	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	COVID-19_Mild\|World / Disease group, lineage and cell class	SRRM1 PPP1R15A DDX3X ELF1 SCAF11	7.47e-05	197	98	5	5c33454b10023decd2f5ccda9229b6512659711e
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	KRT6A KRT6B MUC5B PER2 MUC4	7.47e-05	197	98	5	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CKAP5 LBR DBF4 CKAP2L CDC20	7.47e-05	197	98	5	1c89d6836eed30c50c765f7dde9cc8ee15c363d2
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6A KRT6B PPP4R4 DST MUC4	7.65e-05	198	98	5	77517df37dc894c78ef1e2b24dd7ba31f928bdb7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CKAP5 LBR DBF4 CKAP2L CDC20	7.65e-05	198	98	5	5f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	CKAP5 LBR DBF4 CKAP2L CDC20	7.65e-05	198	98	5	629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell	Caecum-(1)_T_cell-(18)_cycling_gd_T\|Caecum / shred on region, Cell_type, and subtype	GOLGA8N CKAP2L CDC20 GOLGA8O SLX4	7.65e-05	198	98	5	64278d8831c81874937e76b561c53928dfc437c5
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CKAP5 LBR DBF4 CKAP2L CDC20	7.65e-05	198	98	5	c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GOLGA8R MUC5B ARFGEF3 PER2 MUC4	7.65e-05	198	98	5	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell	Caecum-T_cell-cycling_gd_T\|Caecum / Region, Cell class and subclass	GOLGA8N CKAP2L CDC20 GOLGA8O SLX4	7.65e-05	198	98	5	5b719b67f8384863077070e1eb7e04a320e6dab4
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1-28\|World / Primary Cells by Cluster	CKAP5 LBR DBF4 CKAP2L CDC20	7.83e-05	199	98	5	787688b68ae5d8768c0a24673ae07ab07616764a
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CKAP5 LBR DBF4 CKAP2L CDC20	7.83e-05	199	98	5	c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	AKNA GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	7.83e-05	199	98	5	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	Non-neuronal-Dividing-IPC-IPC-div1\|World / Primary Cells by Cluster	CKAP5 LBR DBF4 CKAP2L CDC20	7.83e-05	199	98	5	72823f26ecabcae1b514b7629cfce010c97b929a
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	AKNA GOLGA8R GOLGA8Q GOLGA8N GOLGA8O	7.83e-05	199	98	5	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC5B ARFGEF3 SYTL5 CALML4 MUC4	7.83e-05	199	98	5	7223f853335492ca617dbec3e4b6872a8a463a45
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	SRRM1 SPECC1 DST C5orf24 NFIC	7.83e-05	199	98	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MUC5B ARFGEF3 SYTL5 CALML4 MUC4	7.83e-05	199	98	5	e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	CKAP5 LBR DBF4 CKAP2L CDC20	8.02e-05	200	98	5	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	distal-Epithelial-Proliferating_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B IGF2BP3 KRT6C CDC20	8.02e-05	200	98	5	25cc494ef831511840d8c02ec1bd086635cc7edd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	CKAP5 LBR DBF4 CKAP2L CDC20	8.02e-05	200	98	5	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	distal-Epithelial-Proliferating_Basal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	KRT6A KRT6B IGF2BP3 KRT6C CDC20	8.02e-05	200	98	5	cc31e8c28d01e6757c5dd7f485db6acf7409a47e
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT6A MARK1 RIPK4 PER2 MUC4	8.02e-05	200	98	5	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	Endothelial-H_(cycle)\|World / shred on cell class and cell subclass (v4)	CKAP5 DBF4 CKAP2L CDC20	2.13e-04	133	98	4	8e3005114761feee028c496cc739e607b35d7831
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|GI_small-bowel / Manually curated celltypes from each tissue	WHRN AKNA CKAP2L FRMPD3	2.25e-04	135	98	4	11a672ab6cba7026b8d81d8b216443cb88c0d47a
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_-_proliferative\|E16.5-samps / Age Group, Lineage, Cell class and subclass	KRT6A KRT6B PCDHB9 DIXDC1	2.32e-04	136	98	4	96370f0e3abf1c9ec7a91595b5d0f97ac2ab4b78
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PDE3A MARK1 SPECC1 AMOTL1	2.66e-04	141	98	4	dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ILDR2 GOLGA8N PLEKHH1 DST	3.62e-04	153	98	4	91e9d70a5d3f6fd68c284ed0cc113f03d7d1e10b
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ILDR2 GOLGA8N PLEKHH1 DST	3.62e-04	153	98	4	f17f62646633cf95c810dcd5328978058741b276
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHN1 CABP4 CDC20 GOLGA8O	3.71e-04	154	98	4	9316732964a819a8e935a952faa3823109f90b77
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	IGF2BP3 KIAA1549L RAB11FIP4 FRMPD3	3.81e-04	155	98	4	00eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|390C / Donor, Lineage, Cell class and subclass (all cells)	GCNA MAGEE1 CALML4 SLX4	3.81e-04	155	98	4	afdd0aba0f3788c2fb916ffb453c5dd7cde2304c
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	GCNA PACS2 CALML4 RAB11FIP4	3.90e-04	156	98	4	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGF2BP3 KIAA1549L UBR5 CKAP2L	3.90e-04	156	98	4	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCSK1 LINC00479 ARFGEF3 SRRM3	4.19e-04	159	98	4	7747cef94c55144fddcd024a7495318357f1351b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 C19orf47 PPP1R15A ROBO2	4.19e-04	159	98	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 C19orf47 PPP1R15A ROBO2	4.19e-04	159	98	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ILDR2 C19orf47 PPP1R15A ROBO2	4.19e-04	159	98	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A KRT6B RIPK4 PLEKHH1	4.29e-04	160	98	4	18ae6822915d16699beb9047baeef9b006901a35
ToppCell	390C-Epithelial_cells-Epithelial-H_(AT1)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT6A KRT6B RIPK4 PLEKHH1	4.29e-04	160	98	4	830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_C\|TCGA-Thymus / Sample_Type by Project: Shred V9	IGF2BP3 KIAA1549L RAB11FIP4 MUC4	4.60e-04	163	98	4	2dac87d15051151ccf193760ddd8b82534c3f922
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GOLGA8Q GOLGA8N NRXN2 ALPK3	4.60e-04	163	98	4	f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD MARK1 WEE2 SLX4	4.60e-04	163	98	4	132aece9c79499b4bb3c2bde68d3d7202e1d8772
Drug	SC-791	KRT6A KRT6B KRT75 KRT6C	4.06e-09	6	94	4	CID010291510
Drug	clobestasol propionate	KRT6A KRT6B KRT75 KRT6C	6.22e-07	17	94	4	CID000002791
Drug	dithranol	KRT6A KRT6B KRT75 KRT6C	7.97e-07	18	94	4	CID000002202
Drug	Olux	KRT6A KRT6B KRT75 KRT6C	1.25e-06	20	94	4	CID000032797
Drug	mant-GTP	KRT6A KRT6B LBR KRT75 KRT6C	1.97e-06	50	94	5	CID000128647
Drug	MK-6	KRT6A KRT6B KRT75 KRT6C	2.72e-06	24	94	4	CID005283547
Drug	Bhg-(2-1)fuc	KRT6A KRT6B KRT75 KRT6C	3.22e-06	25	94	4	CID005287784
Drug	AC1L1JLU	KRT6A KRT6B APC KRT75 PER2 KRT6C	4.62e-06	104	94	6	CID000005098
Drug	betamethasone valerate	KRT6A KRT6B KRT75 KRT6C	5.17e-06	28	94	4	CID000016533
Drug	2-Formyl-Protoporphryn Ix	KRT6A KRT6B KRT75 KRT6C	7.87e-06	31	94	4	CID011963946
Drug	AGN 193109	KRT6A KRT6B KRT75 KRT6C	7.87e-06	31	94	4	CID000177238
Drug	torcetrapib	GCNA FSD1L IGF2BP3 DST C5orf24 PER2 AMOTL1 ELF1 SCAF11	1.21e-05	342	94	9	ctd:C483909
Drug	chrysarobin	KRT6A KRT6B KRT75 KRT6C	1.62e-05	37	94	4	CID000068111
Drug	4-hydroxytestosterone	KRT6A KRT6B SAFB KRT75 KRT6C	1.79e-05	78	94	5	CID000160615
Drug	CaLam	KRT6A KRT6B KRT75 KRT6C	2.01e-05	39	94	4	CID004126474
Drug	plakin	KRT6A KRT6B DST KRT75 KRT6C	2.29e-05	82	94	5	CID000018752
Drug	AC1L9LMC	KRT6A KRT6B DST KRT75 KRT6C	2.43e-05	83	94	5	CID000448113
Drug	sodium dodecyl sulfate	KRT6A KRT6B APC KRT75 KRT6C	3.79e-05	91	94	5	CID000008778
Drug	fluorescein	PDE3A MCPH1 PCDHB10 PCDHB9 CASR FCAMR	4.82e-05	157	94	6	CID000016850
Drug	CD-III	KRT6A KRT6B KRT75 KRT6C	6.83e-05	53	94	4	CID000066693
Drug	N1-acetylspermidine	KRT6A KRT6B KRT6C	7.38e-05	20	94	3	CID000000496
Drug	5-Br	HK1 APC AK3	7.38e-05	20	94	3	CID000008057
Drug	DIMIT	KRT6A KRT6B DST KRT6C	8.49e-05	56	94	4	CID000006624
Drug	cignolin	KRT6A KRT6B KRT75 KRT6C	8.49e-05	56	94	4	CID000010187
Disease	hemoglobin A1 measurement	PCSK1 PDE3A HK1 SPECC1 HIVEP3 IGF2BP3 NFIC ELF1 ELF4 SRRM3	4.30e-06	520	90	10	EFO_0007629
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B	5.50e-05	4	90	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B	5.50e-05	4	90	2	DOID:0050449 (is_implicated_in)
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B	5.50e-05	4	90	2	cv:C0265334
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B	5.50e-05	4	90	2	C1721007
Disease	Pachyonychia Congenita	KRT6A KRT6B	9.15e-05	5	90	2	C0265334
Disease	Autistic Disorder	MARK1 APC COP1 NRXN2 ROBO2 DIXDC1	1.51e-04	261	90	6	C0004352
Disease	Headache, glucose measurement	ZNF638 SRRM3	3.27e-04	9	90	2	EFO_0004468, HP_0002315
Disease	otitis media (is_marker_for)	MUC5B MUC4	4.07e-04	10	90	2	DOID:10754 (is_marker_for)
Disease	coagulation factor XA measurement	WHRN AKNA	4.97e-04	11	90	2	EFO_0020266
Disease	Inherited oocyte maturation defect	WEE2 CDC20	1.07e-03	16	90	2	cv:CN238505
Disease	Benign neoplasm of stomach	APC UBR5	1.21e-03	17	90	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	APC UBR5	1.21e-03	17	90	2	C0496905
Disease	Carcinoma in situ of stomach	APC UBR5	1.21e-03	17	90	2	C0154060
Disease	Stomach Carcinoma	APC UBR5	1.86e-03	21	90	2	C0699791
Disease	pulmonary hypertension (biomarker_via_orthology)	PDE3A HK1 CASR	1.90e-03	80	90	3	DOID:6432 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSSSSLGSGSRKRPL	COP1	101	Q8NHY2
PDTVGSTRKSGSTGN	LINC00479	111	Q96M42
DGKSSGPTGLVRSRT	AMER2	91	Q8N7J2
SPASASRVAGTTGTR	AGBL3	716	Q8NEM8
SAGRTPGRTPGKSSS	CDC20	51	Q12834
TSRSRVSSSPGVKGG	ELF1	326	P32519
TERGSGSSKPTGSSR	CALML4	26	Q96GE6
KRTLVGPRGSSSSEG	C19orf47	386	Q8N9M1
RKRSSSLGGSTGSTP	CASR	896	P41180
PTAGKGATSVSNRGT	DIXDC1	496	Q155Q3
AARGPGSSGTDSTRK	ALPK3	576	Q96L96
RSGTGAFTTTKRTGI	SPECC1	91	Q5M775
AGGTSQKSRTEGRPT	AMOTL1	221	Q8IY63
GGTKAPRGTLSRSQS	DENND2B	16	P78524
KSSTSVRDGGKRVGS	DBF4	191	Q9UBU7
SKVDSSGRSSSRGPV	ATG2B	1386	Q96BY7
GTTTPGHTRGTSRTT	MUC5B	3526	Q9HC84
GVSSREQSKVPSGTG	QRICH2	131	Q9H0J4
LGSSVSSSAGQTPRK	RAB11FIP4	246	Q86YS3
PLTSFRQRKGGSTSS	LBR	56	Q14739
DSPTSGKFRRGSGSA	MCOLN1	546	Q9GZU1
KGSSRGRSKSSRFSG	DDX3X	581	O00571
GSAAPSVFSRTRTGT	MUSTN1	51	Q8IVN3
TTPSLKTDGGRRTAT	MUC4	4266	Q99102
PGVSRSGFSSISVSR	KRT6C	26	P48668
SISLVPTRGKGSSTS	MAGEE1	281	Q9HCI5
ISSPRKTGNGEGRAT	MCPH1	481	Q8NEM0
PGVSRSGFSSVSVSR	KRT6A	26	P02538
STRATGIPARFSGSG	IGKV3D-7	76	A0A0C4DH55
SSRVSSRSAPQGKGS	ELF4	331	Q99607
RPGSRAGSKAGSRAS	DST	7491	Q03001
GRSGTPSPKRTSVGS	FSD1L	341	Q9BXM9
PGSGKGTVSSRITTH	AK3	16	Q9UIJ7
RVKPRDSSESTGSGG	PER2	801	O15055
PGVSRSGFSSISVSR	KRT6B	26	P04259
SVRKTGTTGAPAGVT	MUC19	2741	Q7Z5P9
SARSGTSIPSVGKTG	MUC19	3271	Q7Z5P9
PGVTRTTRSSAGLTG	MUC19	3351	Q7Z5P9
TGSSARVTGKTGPSA	MUC19	3676	Q7Z5P9
SRTTRPSAGITGTNG	MUC19	4131	Q7Z5P9
PGGSATTRGRITTAT	MUC19	6611	Q7Z5P9
RGPRGSQSSGTSITV	PDE3A	331	Q14432
RVSSGSSERGSKSPL	GLYR1	146	Q49A26
RKTNGSIPETATSGG	GOLGA8Q	36	H3BV12
DGRKGSISVNSRSTP	NRXN2	596	Q9P2S2
VISNESGKPSSGRRS	KIAA1549L	1296	Q6ZVL6
KTRSLGGRQPSDSVS	PACS2	356	Q86VP3
DGGSPSRSGTSTVRI	PCDHB10	216	Q9UN67
KGTPRLRTTVGVDGS	HK1	401	P19367
RGTVTGVRKDASTSP	KIAA1328	471	Q86T90
QRGSSRQGSPGSVSK	IGF2BP3	176	O00425
REGKGRISTSTGISP	CKAP5	1891	Q14008
TSKTTASAEGRRTPG	FCAMR	226	Q8WWV6
SRKRTGSSGEQTGPE	CABP4	51	P57796
RSGKRGRPSGTTKSA	C5orf24	86	Q7Z6I8
GRPSGTTKSAGYRTS	C5orf24	91	Q7Z6I8
PGGGSSTLTGRVTTK	COL20A1	631	Q9P218
PKRRKSDSGSTSGGS	CCNL2	401	Q96S94
VGSVGTSPRKSSRCT	FRMPD3	536	Q5JV73
RTASRSTSPTRGGGN	FAM117B	86	Q6P1L5
KRPRSGSTGSSLSVS	ARFGEF3	2091	Q5TH69
VRRSSGGASSSKSPG	ATOH1	106	Q92858
PGSATSGAEKATTRR	AKNA	1286	Q7Z591
SGRTDTSRSTSGEPK	MARK1	671	Q9P0L2
SGDTSGSSVARRAPK	GCNA	56	Q96QF7
RKTNGSIPETATSGG	GOLGA8R	36	I6L899
RKTNGSIPETATSGG	GOLGA8O	36	A6NCC3
IGTGTVTRKGSTFRP	DCBLD1	546	Q8N8Z6
EGSKSSGSTRNTLRP	DVL1P1	546	P54792
TSGTSNTRGSRRKPA	SCAF11	301	Q99590
TGPVTVKTSGTRFGA	OLFM3	226	Q96PB7
KGARKTSVSPRSSGS	PPP1R15A	241	O75807
DGGSPSRSGTSTIRI	PCDHB9	216	Q9Y5E1
RTPKSSRSNGVTPGT	SYTL5	246	Q8TDW5
GAATRGTARTSKPTT	HHLA1	226	C9JL84
GRKTGSQRSSGSRSP	SRRM3	286	A6NNA2
SSRSPGSKARAEGRG	PLEKHN1	406	Q494U1
TSRGTGNSVDPKSSG	PPP4R4	841	Q6NUP7
VIKRISGGSGSGSSP	PSD	731	A5PKW4
PGRGRQSVSTKSRSS	WHRN	776	Q9P202
GLRRTLPSTSSSGSK	NFIC	266	P08651
PSSGSGKRLSGVSSV	RIPK4	411	P57078
PSERSRATKSGSRGT	SAFB	546	Q15424
TSGSSLSTPRSRGGT	SLX4	1051	Q8IY92
QIGGSSKAPSRSGSR	APC	2291	P25054
AGSSTTGELSRKPVG	CKAP2L	126	Q8IYA6
VGSSGRSPSKAVAAR	SEC61B	11	P60468
GASRGGSLETPSKRS	ILDR2	541	Q71H61
SRVSVSPGRTSGKVT	SRRM1	426	Q8IYB3
GGKSTIRDRSSGTAS	PRPF31	436	Q8WWY3
SSSTAGGSKRVLSPA	HIVEP3	1421	Q5T1R4
SSGTASSKGSTGPRK	ROBO2	1331	Q9HCK4
VSPKRGSTAGGTRLT	PKHD1L1	2096	Q86WI1
SSESRKTSGLGSPRA	PLEKHH1	511	Q9ULM0
GTHTGSRSTKRLVGG	WEE2	536	P0C1S8
TPSAKGRRSHTGSVG	TOGARAM1	1436	Q9Y4F4
IRSRSSSSSSGGGLL	ZFC3H1	36	O60293
FKPTQSSLTRGGSGR	ZNF638	1456	Q14966
SGAGRTSRPGRTSDS	UBR5	96	O95071
RKTNGSIPETATSGG	GOLGA8N	36	F8WBI6
SGSRRGFSTTSAITP	KRT75	11	O95678
SGRGESTTSRISPGS	MUC12	1211	Q9UKN1
TKLSPARSTTSGLVG	MUC12	1396	Q9UKN1
SGRGESTTSRISPGS	MUC12	3851	Q9UKN1
TKLSPARSTTSGLVG	MUC12	4036	Q9UKN1
GSARRKVTGTAESGT	MYOZ3	76	Q8TDC0
LVSKSPSSSSVGGRR	PCSK1	641	P29120