Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	VLDLR LRP2 LRP1B LDLR SORL1	3.37e-09	16	78	5	GO:0005041
GeneOntologyMolecularFunction	calcium ion binding	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN F2 LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	3.54e-09	749	78	17	GO:0005509
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	VLDLR LRP2 LRP1B LDLR SORL1	1.55e-08	21	78	5	GO:0030228
GeneOntologyMolecularFunction	cargo receptor activity	VLDLR LRP2 CUBN LRP1B LDLR SORL1	1.00e-06	85	78	6	GO:0038024
GeneOntologyMolecularFunction	very-low-density lipoprotein particle receptor activity	VLDLR LDLR	8.99e-05	4	78	2	GO:0030229
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL11A2 TNC LAMA3 NID1 LTBP4 MUC4	9.41e-05	188	78	6	GO:0005201
GeneOntologyMolecularFunction	lipoprotein particle binding	VLDLR LDLR SORL1	3.43e-04	35	78	3	GO:0071813
GeneOntologyMolecularFunction	protein-lipid complex binding	VLDLR LDLR SORL1	3.43e-04	35	78	3	GO:0071814
GeneOntologyMolecularFunction	integrin binding	ITGBL1 TNC L1CAM LTBP4 SVEP1	6.15e-04	175	78	5	GO:0005178
GeneOntologyMolecularFunction	hemoglobin binding	LRP2 CUBN	8.10e-04	11	78	2	GO:0030492
GeneOntologyMolecularFunction	axon guidance receptor activity	L1CAM EPHA7	1.14e-03	13	78	2	GO:0008046
GeneOntologyBiologicalProcess	regulation of neurogenesis	JADE2 NCAN L1CAM LRP2 LRP4 RELA F2 LDLR NOTCH1 NOTCH2 EPHA7 SORL1	5.02e-07	515	78	12	GO:0050767
GeneOntologyBiologicalProcess	positive regulation of neural precursor cell proliferation	FLNA EGF NCAN LRP2 NOTCH1 NOTCH2	5.79e-07	80	78	6	GO:2000179
GeneOntologyBiologicalProcess	regulation of nervous system development	JADE2 NCAN L1CAM LRP2 LRP4 RELA F2 LDLR NOTCH1 NOTCH2 EPHA7 SORL1	3.77e-06	625	78	12	GO:0051960
GeneOntologyBiologicalProcess	regulation of neural precursor cell proliferation	FLNA EGF NCAN LRP2 NOTCH1 NOTCH2	1.23e-05	135	78	6	GO:2000177
GeneOntologyBiologicalProcess	endocytic hemoglobin import into cell	LRP2 CUBN	1.41e-05	2	78	2	GO:0020028
GeneOntologyBiologicalProcess	receptor-mediated endocytosis	SMAP1 VLDLR EGF LRP2 CUBN LRP1B LDLR SORL1	4.05e-05	337	78	8	GO:0006898
GeneOntologyBiologicalProcess	cellular response to tumor cell	NOTCH1 NOTCH2	4.23e-05	3	78	2	GO:0071228
GeneOntologyBiologicalProcess	negative regulation of neurogenesis	LRP4 F2 LDLR NOTCH1 EPHA7 SORL1	4.97e-05	173	78	6	GO:0050768
GeneOntologyBiologicalProcess	regulation of cell development	SMAP1 JADE2 NCAN L1CAM LRP2 LRP4 RELA CD46 F2 LDLR NOTCH1 NOTCH2 EPHA7 SORL1	5.50e-05	1095	78	14	GO:0060284
GeneOntologyBiologicalProcess	negative regulation of nervous system development	LRP4 F2 LDLR NOTCH1 EPHA7 SORL1	7.01e-05	184	78	6	GO:0051961
GeneOntologyBiologicalProcess	mitral valve formation	NOTCH1 ZFPM2	1.40e-04	5	78	2	GO:0003192
GeneOntologyBiologicalProcess	positive regulation of lysosomal protein catabolic process	LRP2 LDLR	1.40e-04	5	78	2	GO:1905167
GeneOntologyBiologicalProcess	response to tumor cell	RELA MUC4 NOTCH1 NOTCH2	1.52e-04	71	78	4	GO:0002347
GeneOntologyBiologicalProcess	cell-substrate adhesion	SNED1 FLNA ITGBL1 L1CAM NID1 MUC4 SVEP1 NOTCH1	1.58e-04	410	78	8	GO:0031589
GeneOntologyBiologicalProcess	regulation of cell adhesion	FLNA TIGIT TNC L1CAM LAMA3 NID1 RELA CD46 MUC4 NOTCH1 LAX1 EPHA7	1.78e-04	927	78	12	GO:0030155
GeneOntologyBiologicalProcess	cell-cell adhesion	NPHS1 FLNA ITGBL1 TIGIT L1CAM LAMA3 RELA CD46 MUC4 SVEP1 NOTCH1 LAX1 EPHA7	1.86e-04	1077	78	13	GO:0098609
GeneOntologyBiologicalProcess	limb development	TBC1D32 ZNRF3 LRP4 SIK3 NOTCH1 NOTCH2	2.05e-04	224	78	6	GO:0060173
GeneOntologyBiologicalProcess	appendage development	TBC1D32 ZNRF3 LRP4 SIK3 NOTCH1 NOTCH2	2.05e-04	224	78	6	GO:0048736
GeneOntologyBiologicalProcess	neural precursor cell proliferation	FLNA EGF NCAN LRP2 NOTCH1 NOTCH2	2.54e-04	233	78	6	GO:0061351
GeneOntologyBiologicalProcess	regulation of gliogenesis	LRP2 RELA F2 LDLR NOTCH1	2.70e-04	151	78	5	GO:0014013
GeneOntologyBiologicalProcess	cell junction organization	NPHS1 GABRG2 VLDLR FLNA INSYN1 TNC NCAN L1CAM LAMA3 LRP4 SVEP1 EPHA7	2.81e-04	974	78	12	GO:0034330
GeneOntologyBiologicalProcess	coronary vasculature morphogenesis	LRP2 NOTCH1 ZFPM2	2.86e-04	34	78	3	GO:0060977
GeneOntologyBiologicalProcess	positive regulation of protein catabolic process in the vacuole	LRP2 LDLR	2.93e-04	7	78	2	GO:1904352
GeneOntologyBiologicalProcess	cardiac septum morphogenesis	LRP2 NOTCH1 NOTCH2 ZFPM2	3.62e-04	89	78	4	GO:0060411
GeneOntologyBiologicalProcess	positive regulation of neurogenesis	JADE2 NCAN L1CAM LRP2 RELA NOTCH1 NOTCH2	3.84e-04	354	78	7	GO:0050769
GeneOntologyBiologicalProcess	amyloid-beta clearance by cellular catabolic process	LRP4 LDLR	3.90e-04	8	78	2	GO:0150094
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	CD46 SVEP1	3.90e-04	8	78	2	GO:0045959
GeneOntologyBiologicalProcess	negative regulation of glial cell differentiation	F2 LDLR NOTCH1	4.31e-04	39	78	3	GO:0045686
GeneOntologyBiologicalProcess	amyloid-beta clearance	LRP2 LRP4 LDLR	4.65e-04	40	78	3	GO:0097242
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	ZCCHC18 EGF CCBE1 ERO1A LRP2 LRP4 RELA LTBP4 SVEP1 NOTCH1 NOTCH2 EPHA7 SORL1	4.72e-04	1186	78	13	GO:0007167
GeneOntologyBiologicalProcess	atrioventricular node development	NOTCH1 NOTCH2	5.00e-04	9	78	2	GO:0003162
GeneOntologyBiologicalProcess	atrioventricular valve formation	NOTCH1 ZFPM2	5.00e-04	9	78	2	GO:0003190
GeneOntologyBiologicalProcess	kidney development	TBC1D32 LRP2 LRP4 NID1 NOTCH1 NOTCH2 EPHA7	5.16e-04	372	78	7	GO:0001822
GeneOntologyBiologicalProcess	cell-matrix adhesion	SNED1 ITGBL1 L1CAM NID1 MUC4 SVEP1	5.56e-04	270	78	6	GO:0007160
GeneOntologyBiologicalProcess	regulation of astrocyte differentiation	F2 LDLR NOTCH1	5.76e-04	43	78	3	GO:0048710
GeneOntologyBiologicalProcess	positive regulation of neuroblast proliferation	NCAN NOTCH1 NOTCH2	6.16e-04	44	78	3	GO:0002052
GeneOntologyBiologicalProcess	regulation of protein localization to early endosome	EGF SORL1	6.23e-04	10	78	2	GO:1902965
GeneOntologyBiologicalProcess	positive regulation of protein localization to early endosome	EGF SORL1	6.23e-04	10	78	2	GO:1902966
GeneOntologyBiologicalProcess	coronary artery morphogenesis	LRP2 NOTCH1	6.23e-04	10	78	2	GO:0060982
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	CD46 SVEP1	6.23e-04	10	78	2	GO:0030450
GeneOntologyBiologicalProcess	cobalamin transport	LRP2 CUBN	6.23e-04	10	78	2	GO:0015889
GeneOntologyBiologicalProcess	renal system development	TBC1D32 LRP2 LRP4 NID1 NOTCH1 NOTCH2 EPHA7	6.43e-04	386	78	7	GO:0072001
GeneOntologyBiologicalProcess	regulation of glial cell differentiation	RELA F2 LDLR NOTCH1	6.53e-04	104	78	4	GO:0045685
GeneOntologyBiologicalProcess	appendage morphogenesis	TBC1D32 LRP4 SIK3 NOTCH1 NOTCH2	6.84e-04	185	78	5	GO:0035107
GeneOntologyBiologicalProcess	limb morphogenesis	TBC1D32 LRP4 SIK3 NOTCH1 NOTCH2	6.84e-04	185	78	5	GO:0035108
GeneOntologyBiologicalProcess	axon development	FLNA TNC L1CAM LRP2 LAMA3 LRP4 NOTCH1 NOTCH2 EPHA7	6.98e-04	642	78	9	GO:0061564
GeneOntologyBiologicalProcess	axon guidance	L1CAM LRP2 LAMA3 NOTCH1 NOTCH2 EPHA7	7.37e-04	285	78	6	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	L1CAM LRP2 LAMA3 NOTCH1 NOTCH2 EPHA7	7.51e-04	286	78	6	GO:0097485
GeneOntologyBiologicalProcess	animal organ morphogenesis	FLNA COL11A2 PNPLA6 TNC LRP2 LAMA3 LRP4 RELA SIK3 CERT1 NOTCH1 NOTCH2 ZFPM2	8.89e-04	1269	78	13	GO:0009887
GeneOntologyBiologicalProcess	embryo development	TBC1D32 ZFP42 NSD1 LRP2 LAMA3 LRP4 CUBN CERT1 LRP1B KAT14 GINS1 NOTCH1 NOTCH2 ZFPM2	9.02e-04	1437	78	14	GO:0009790
GeneOntologyBiologicalProcess	BMP signaling pathway	ZCCHC18 LRP2 NOTCH1 NOTCH2 SORL1	9.07e-04	197	78	5	GO:0030509
GeneOntologyBiologicalProcess	regulation of lysosomal protein catabolic process	LRP2 LDLR	9.09e-04	12	78	2	GO:1905165
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	CD46 SVEP1	9.09e-04	12	78	2	GO:0002924
GeneOntologyBiologicalProcess	blood vessel morphogenesis	FLNA PNPLA6 EGF CCBE1 LRP2 RELA LDLR NOTCH1 NOTCH2 ZFPM2	9.90e-04	817	78	10	GO:0048514
GeneOntologyBiologicalProcess	tube morphogenesis	FLNA PNPLA6 EGF TNC CCBE1 LRP2 RELA LDLR NOTCH1 NOTCH2 ZFPM2 EPHA7	1.01e-03	1125	78	12	GO:0035239
GeneOntologyBiologicalProcess	vasculature development	FLNA PNPLA6 EGF CCBE1 LRP2 RELA LDLR SVEP1 NOTCH1 NOTCH2 ZFPM2	1.01e-03	969	78	11	GO:0001944
GeneOntologyBiologicalProcess	positive regulation of nervous system development	JADE2 NCAN L1CAM LRP2 RELA NOTCH1 NOTCH2	1.02e-03	418	78	7	GO:0051962
GeneOntologyBiologicalProcess	venous blood vessel morphogenesis	CCBE1 NOTCH1	1.07e-03	13	78	2	GO:0048845
GeneOntologyBiologicalProcess	synapse organization	GABRG2 VLDLR FLNA INSYN1 TNC NCAN L1CAM LRP4 EPHA7	1.10e-03	685	78	9	GO:0050808
GeneOntologyBiologicalProcess	hair follicle development	LRP4 RELA KRT25 NOTCH1	1.22e-03	123	78	4	GO:0001942
GeneOntologyBiologicalProcess	peptidyl-proline hydroxylation	ERO1A CRTAP	1.25e-03	14	78	2	GO:0019511
GeneOntologyBiologicalProcess	positive regulation of protein localization to endosome	EGF SORL1	1.25e-03	14	78	2	GO:1905668
GeneOntologyBiologicalProcess	positive regulation of integrin-mediated signaling pathway	FLNA NID1	1.25e-03	14	78	2	GO:2001046
GeneOntologyBiologicalProcess	regulation of protein catabolic process in the vacuole	LRP2 LDLR	1.25e-03	14	78	2	GO:1904350
GeneOntologyBiologicalProcess	negative regulation of complement activation	CD46 SVEP1	1.25e-03	14	78	2	GO:0045916
GeneOntologyBiologicalProcess	left/right axis specification	NOTCH1 NOTCH2	1.25e-03	14	78	2	GO:0070986
GeneOntologyBiologicalProcess	positive regulation of platelet activation	FLNA SVEP1	1.25e-03	14	78	2	GO:0010572
GeneOntologyBiologicalProcess	gliogenesis	NCAN LRP2 RELA F2 LDLR NOTCH1 NOTCH2	1.29e-03	435	78	7	GO:0042063
GeneOntologyBiologicalProcess	molting cycle process	LRP4 RELA KRT25 NOTCH1	1.34e-03	126	78	4	GO:0022404
GeneOntologyBiologicalProcess	hair cycle process	LRP4 RELA KRT25 NOTCH1	1.34e-03	126	78	4	GO:0022405
GeneOntologyBiologicalProcess	response to BMP	ZCCHC18 LRP2 NOTCH1 NOTCH2 SORL1	1.34e-03	215	78	5	GO:0071772
GeneOntologyBiologicalProcess	cellular response to BMP stimulus	ZCCHC18 LRP2 NOTCH1 NOTCH2 SORL1	1.34e-03	215	78	5	GO:0071773
GeneOntologyBiologicalProcess	glial cell differentiation	NCAN RELA F2 LDLR NOTCH1 NOTCH2	1.36e-03	321	78	6	GO:0010001
GeneOntologyBiologicalProcess	heart morphogenesis	FLNA LRP2 CERT1 NOTCH1 NOTCH2 ZFPM2	1.36e-03	321	78	6	GO:0003007
GeneOntologyBiologicalProcess	mitral valve morphogenesis	NOTCH1 ZFPM2	1.44e-03	15	78	2	GO:0003183
GeneOntologyBiologicalProcess	regulation of protein localization to endosome	EGF SORL1	1.44e-03	15	78	2	GO:1905666
GeneOntologyBiologicalProcess	regulation of triglyceride catabolic process	LDLR SORL1	1.44e-03	15	78	2	GO:0010896
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue morphogenesis	LRP2 NOTCH1 ZFPM2	1.45e-03	59	78	3	GO:0055010
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	ZCCHC18 ERO1A LRP2 LTBP4 NOTCH1 NOTCH2 SORL1	1.47e-03	445	78	7	GO:0141091
GeneOntologyBiologicalProcess	regulation of BMP signaling pathway	LRP2 NOTCH1 NOTCH2 SORL1	1.54e-03	131	78	4	GO:0030510
GeneOntologyBiologicalProcess	regulation of cell-cell adhesion	TIGIT L1CAM RELA CD46 MUC4 NOTCH1 LAX1 EPHA7	1.55e-03	580	78	8	GO:0022407
GeneOntologyBiologicalProcess	mitral valve development	NOTCH1 ZFPM2	1.64e-03	16	78	2	GO:0003174
GeneOntologyBiologicalProcess	protein localization to early endosome	EGF SORL1	1.64e-03	16	78	2	GO:1902946
GeneOntologyBiologicalProcess	negative regulation of B cell mediated immunity	CD46 SVEP1	1.64e-03	16	78	2	GO:0002713
GeneOntologyBiologicalProcess	negative regulation of immunoglobulin mediated immune response	CD46 SVEP1	1.64e-03	16	78	2	GO:0002890
GeneOntologyBiologicalProcess	cardiac septum development	LRP2 NOTCH1 NOTCH2 ZFPM2	1.68e-03	134	78	4	GO:0003279
GeneOntologyBiologicalProcess	negative regulation of gliogenesis	F2 LDLR NOTCH1	1.68e-03	62	78	3	GO:0014014
GeneOntologyBiologicalProcess	cell morphogenesis	VLDLR FLNA JADE2 L1CAM LRP2 LAMA3 LRP4 F2 CERT1 NOTCH1 NOTCH2 EPHA7	1.68e-03	1194	78	12	GO:0000902
GeneOntologyBiologicalProcess	heart valve morphogenesis	NOTCH1 NOTCH2 ZFPM2	1.75e-03	63	78	3	GO:0003179
GeneOntologyBiologicalProcess	response to growth factor	ZCCHC18 TNC CCBE1 ERO1A LRP2 RELA LTBP4 NOTCH1 NOTCH2 SORL1	1.77e-03	883	78	10	GO:0070848
GeneOntologyCellularComponent	extracellular matrix	NPHS1 SNED1 COL11A2 FCGBP MEGF6 TNC CCBE1 NCAN L1CAM LAMA3 NID1 F2 LTBP4 MUC4 SVEP1	2.02e-08	656	79	15	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	NPHS1 SNED1 COL11A2 FCGBP MEGF6 TNC CCBE1 NCAN L1CAM LAMA3 NID1 F2 LTBP4 MUC4 SVEP1	2.10e-08	658	79	15	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	NPHS1 COL11A2 MEGF6 TNC NCAN L1CAM LAMA3 NID1 F2 LTBP4 MUC4	4.78e-06	530	79	11	GO:0062023
GeneOntologyCellularComponent	cell surface	HYAL4 VLDLR ITGBL1 TIGIT L1CAM LRP2 LRP4 CORIN CD46 CUBN F2 LDLR NOTCH1 NOTCH2 SORL1	1.52e-05	1111	79	15	GO:0009986
GeneOntologyCellularComponent	receptor complex	GABRG2 VLDLR FLNA ITGBL1 LRP2 CUBN LRP1B LDLR NOTCH1 NOTCH2	6.55e-05	581	79	10	GO:0043235
GeneOntologyCellularComponent	clathrin-coated pit	VLDLR LRP2 CUBN LDLR	2.40e-04	80	79	4	GO:0005905
GeneOntologyCellularComponent	cell-substrate junction	NPHS1 FLNA ITGBL1 FLNC TNC L1CAM LAMA3 CD46	2.67e-04	443	79	8	GO:0030055
GeneOntologyCellularComponent	axonal growth cone	FLNA L1CAM LRP2	6.58e-04	45	79	3	GO:0044295
GeneOntologyCellularComponent	perisynaptic extracellular matrix	TNC NCAN	7.59e-04	11	79	2	GO:0098966
GeneOntologyCellularComponent	Golgi lumen	ERO1A NCAN F2 MUC4	7.78e-04	109	79	4	GO:0005796
GeneOntologyCellularComponent	synapse-associated extracellular matrix	TNC NCAN	1.07e-03	13	79	2	GO:0099535
GeneOntologyCellularComponent	basement membrane	NPHS1 TNC LAMA3 NID1	1.18e-03	122	79	4	GO:0005604
GeneOntologyCellularComponent	focal adhesion	NPHS1 FLNA ITGBL1 FLNC TNC L1CAM CD46	1.22e-03	431	79	7	GO:0005925
GeneOntologyCellularComponent	protein complex involved in cell adhesion	ITGBL1 TNC NID1	1.45e-03	59	79	3	GO:0098636
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	TNC NID1	1.85e-03	17	79	2	GO:0098637
Domain	EGF	TMEFF1 HYAL4 SNED1 VLDLR ITGBL1 FCGBP EGF MEGF6 TNC CCBE1 NCAN LRP2 LAMA3 LRP4 NID1 CUBN LTBP4 MUC4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2 SORL1	3.27e-27	235	78	24	SM00181
Domain	EGF_2	TMEFF1 HYAL4 SNED1 VLDLR ITGBL1 EGF MEGF6 TNC CCBE1 NCAN LRP2 LAMA3 LRP4 NID1 CUBN LTBP4 MUC4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2 EPHA7 SORL1	6.19e-26	265	78	24	PS01186
Domain	EGF-like_dom	TMEFF1 SNED1 VLDLR ITGBL1 FCGBP EGF MEGF6 TNC CCBE1 NCAN LRP2 LAMA3 LRP4 NID1 CUBN LTBP4 MUC4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2 SORL1	4.81e-25	249	78	23	IPR000742
Domain	EGF-like_CS	TMEFF1 SNED1 VLDLR EGF MEGF6 TNC CCBE1 NCAN LRP2 LAMA3 LRP4 NID1 CUBN ZNRF4 LTBP4 MUC4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2 EPHA7 SORL1	1.44e-24	261	78	23	IPR013032
Domain	EGF_1	TMEFF1 HYAL4 SNED1 VLDLR ITGBL1 EGF MEGF6 TNC CCBE1 NCAN LRP2 LAMA3 LRP4 NID1 CUBN LTBP4 MUC4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	2.72e-23	255	78	22	PS00022
Domain	EGF_Ca-bd_CS	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	1.02e-21	97	78	16	IPR018097
Domain	EGF_CA	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	1.44e-21	99	78	16	PS01187
Domain	ASX_HYDROXYL	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	1.71e-21	100	78	16	PS00010
Domain	EGF_3	TMEFF1 SNED1 VLDLR EGF MEGF6 TNC CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 MUC4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2 SORL1	4.54e-21	235	78	20	PS50026
Domain	EGF-type_Asp/Asn_hydroxyl_site	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	4.59e-21	106	78	16	IPR000152
Domain	EGF_CA	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	4.88e-20	122	78	16	SM00179
Domain	EGF-like_Ca-bd_dom	SNED1 VLDLR EGF MEGF6 CCBE1 NCAN LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	6.40e-20	124	78	16	IPR001881
Domain	EGF_CA	VLDLR EGF MEGF6 CCBE1 LRP2 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2	5.14e-19	86	78	14	PF07645
Domain	Growth_fac_rcpt_	VLDLR EGF MEGF6 TNC LRP2 LAMA3 LRP4 NID1 CUBN LTBP4 LRP1B LDLR SVEP1 NOTCH1 NOTCH2 EPHA7	2.82e-18	156	78	16	IPR009030
Domain	EGF	SNED1 VLDLR EGF MEGF6 TNC NCAN LRP2 LRP4 NID1 CUBN MUC4 LRP1B SVEP1 NOTCH1 NOTCH2	3.54e-18	126	78	15	PF00008
Domain	Ldl_recept_b	VLDLR EGF LRP2 LRP4 NID1 LRP1B LDLR SORL1	1.88e-16	14	78	8	PF00058
Domain	LDLRB	VLDLR EGF LRP2 LRP4 NID1 LRP1B LDLR SORL1	1.88e-16	14	78	8	PS51120
Domain	LY	VLDLR EGF LRP2 LRP4 NID1 LRP1B LDLR SORL1	4.02e-16	15	78	8	SM00135
Domain	LDLR_classB_rpt	VLDLR EGF LRP2 LRP4 NID1 LRP1B LDLR SORL1	4.02e-16	15	78	8	IPR000033
Domain	-	VLDLR EGF LRP2 LRP4 NID1 LRP1B LDLR SORL1	3.55e-12	39	78	8	2.120.10.30
Domain	LDLR_class-A_CS	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	4.42e-12	40	78	8	IPR023415
Domain	Ldl_recept_a	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	1.22e-11	45	78	8	PF00057
Domain	-	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	1.47e-11	46	78	8	4.10.400.10
Domain	6-blade_b-propeller_TolB-like	VLDLR EGF LRP2 LRP4 NID1 LRP1B LDLR SORL1	1.47e-11	46	78	8	IPR011042
Domain	LDLRA_1	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	2.11e-11	48	78	8	PS01209
Domain	LDLRA_2	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	2.51e-11	49	78	8	PS50068
Domain	LDrepeatLR_classA_rpt	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	2.51e-11	49	78	8	IPR002172
Domain	LDLa	VLDLR TMPRSS3 LRP2 LRP4 CORIN LRP1B LDLR SORL1	2.51e-11	49	78	8	SM00192
Domain	EGF_extracell	ITGBL1 MEGF6 TNC LRP2 LRP1B SVEP1 NOTCH1	5.44e-09	60	78	7	IPR013111
Domain	EGF_2	ITGBL1 MEGF6 TNC LRP2 LRP1B SVEP1 NOTCH1	5.44e-09	60	78	7	PF07974
Domain	hEGF	SNED1 MEGF6 SVEP1 NOTCH1 NOTCH2	1.02e-07	28	78	5	PF12661
Domain	NIDO_dom	SNED1 NID1 MUC4	6.97e-07	5	78	3	IPR003886
Domain	NIDO	SNED1 NID1 MUC4	6.97e-07	5	78	3	SM00539
Domain	NIDO	SNED1 NID1 MUC4	6.97e-07	5	78	3	PF06119
Domain	NIDO	SNED1 NID1 MUC4	6.97e-07	5	78	3	PS51220
Domain	cEGF	LRP2 LRP4 NID1 LRP1B	3.92e-06	26	78	4	IPR026823
Domain	cEGF	LRP2 LRP4 NID1 LRP1B	3.92e-06	26	78	4	PF12662
Domain	-	EGF NID1 SVEP1	1.13e-05	11	78	3	2.40.155.10
Domain	GFP-like	EGF NID1 SVEP1	1.13e-05	11	78	3	IPR023413
Domain	FN3	NPHS1 SNED1 FLNC TNC L1CAM EPHA7 SORL1	1.22e-05	185	78	7	SM00060
Domain	FN3_dom	NPHS1 SNED1 FLNC TNC L1CAM EPHA7 SORL1	2.68e-05	209	78	7	IPR003961
Domain	DUF3454	NOTCH1 NOTCH2	5.15e-05	3	78	2	PF11936
Domain	DUF3454_notch	NOTCH1 NOTCH2	5.15e-05	3	78	2	IPR024600
Domain	DUF3454	NOTCH1 NOTCH2	5.15e-05	3	78	2	SM01334
Domain	fn3	NPHS1 SNED1 TNC L1CAM EPHA7 SORL1	5.95e-05	162	78	6	PF00041
Domain	CCP	SNED1 NCAN CD46 SVEP1	7.60e-05	54	78	4	SM00032
Domain	SUSHI	SNED1 NCAN CD46 SVEP1	8.77e-05	56	78	4	PS50923
Domain	-	NPHS1 SNED1 FLNA FLNC TIGIT TNC NCAN L1CAM RELA EPHA7 SORL1	9.29e-05	663	78	11	2.60.40.10
Domain	Sushi_SCR_CCP_dom	SNED1 NCAN CD46 SVEP1	9.40e-05	57	78	4	IPR000436
Domain	Notch	NOTCH1 NOTCH2	1.03e-04	4	78	2	IPR008297
Domain	NODP	NOTCH1 NOTCH2	1.03e-04	4	78	2	PF07684
Domain	Notch_NODP_dom	NOTCH1 NOTCH2	1.03e-04	4	78	2	IPR011656
Domain	Notch_NOD_dom	NOTCH1 NOTCH2	1.03e-04	4	78	2	IPR010660
Domain	NOD	NOTCH1 NOTCH2	1.03e-04	4	78	2	PF06816
Domain	NOD	NOTCH1 NOTCH2	1.03e-04	4	78	2	SM01338
Domain	NODP	NOTCH1 NOTCH2	1.03e-04	4	78	2	SM01339
Domain	Ig-like_fold	NPHS1 SNED1 FLNA FLNC TIGIT TNC NCAN L1CAM RELA EPHA7 SORL1	1.61e-04	706	78	11	IPR013783
Domain	LNR	NOTCH1 NOTCH2	1.71e-04	5	78	2	PS50258
Domain	FN3	NPHS1 SNED1 TNC L1CAM EPHA7 SORL1	1.84e-04	199	78	6	PS50853
Domain	Notch_dom	NOTCH1 NOTCH2	3.57e-04	7	78	2	IPR000800
Domain	Notch	NOTCH1 NOTCH2	3.57e-04	7	78	2	PF00066
Domain	SRCR_2	TMPRSS3 CORIN	3.57e-04	7	78	2	PF15494
Domain	NL	NOTCH1 NOTCH2	3.57e-04	7	78	2	SM00004
Domain	IG_FLMN	FLNA FLNC	7.58e-04	10	78	2	SM00557
Domain	Filamin	FLNA FLNC	9.24e-04	11	78	2	PF00630
Domain	Fol_N	SNED1 FCGBP	9.24e-04	11	78	2	IPR003645
Domain	Ephrin_rec_like	SVEP1 EPHA7	9.24e-04	11	78	2	PF07699
Domain	FILAMIN_REPEAT	FLNA FLNC	9.24e-04	11	78	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNC	9.24e-04	11	78	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNC	9.24e-04	11	78	2	IPR017868
Domain	FOLN	SNED1 FCGBP	9.24e-04	11	78	2	SM00274
Domain	EGF_3	NID1 CUBN	1.11e-03	12	78	2	PF12947
Domain	EGF_dom	NID1 CUBN	1.11e-03	12	78	2	IPR024731
Domain	zf-RING_2	PJA2 ZNRF3 ZNRF4	1.34e-03	52	78	3	PF13639
Domain	Sushi	NCAN CD46 SVEP1	1.34e-03	52	78	3	PF00084
Domain	TIL_dom	FCGBP LRP2	1.52e-03	14	78	2	IPR002919
Domain	VWD	FCGBP MUC4	1.99e-03	16	78	2	SM00216
Domain	VWF_type-D	FCGBP MUC4	1.99e-03	16	78	2	IPR001846
Domain	VWFD	FCGBP MUC4	1.99e-03	16	78	2	PS51233
Domain	VWD	FCGBP MUC4	1.99e-03	16	78	2	PF00094
Domain	Actinin_actin-bd_CS	FLNA FLNC	4.12e-03	23	78	2	IPR001589
Domain	ACTININ_2	FLNA FLNC	4.12e-03	23	78	2	PS00020
Domain	ACTININ_1	FLNA FLNC	4.12e-03	23	78	2	PS00019
Pathway	WP_VITAMIN_B12_METABOLISM	LRP2 RELA CUBN F2 LDLR	4.73e-06	54	65	5	M39337
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	COL11A2 TNC NCAN LAMA3 LRP4 NID1 LTBP4 CRTAP	6.75e-05	300	65	8	M610
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI	SEL1L NOTCH1 NOTCH2	7.27e-05	18	65	3	M614
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH1 NOTCH2	2.07e-04	5	65	2	M27411
Pathway	PID_INTEGRIN1_PATHWAY	COL11A2 TNC LAMA3 NID1	2.39e-04	66	65	4	M18
Pathway	KEGG_FOCAL_ADHESION	FLNA FLNC COL11A2 EGF TNC LAMA3	3.03e-04	199	65	6	M7253
Pathway	REACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM	NOTCH1 NOTCH2	3.10e-04	6	65	2	M27068
Pathway	WP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES	VLDLR TMPRSS3 LRP2 LRP4 CUBN LRP1B LDLR SORL1	3.48e-04	381	65	8	M48063
Pathway	REACTOME_ECM_PROTEOGLYCANS	TNC NCAN LAMA3 LRP4	4.12e-04	76	65	4	M27219
Pathway	PID_SYNDECAN_4_PATHWAY	TNC LAMA3 F2	4.22e-04	32	65	3	M165
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	VLDLR LRP2 LRP4 LRP1B LDLR	1.05e-09	21	79	5	21337463
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL11A2 MEGF6 TNC LAMA3 NID1 F2 LTBP4 MUC4	6.73e-09	175	79	8	28071719
Pubmed	HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.	NPHS1 LRP2 CUBN NOTCH1 NOTCH2	3.29e-08	40	79	5	23362348
Pubmed	Developmental regulation of LR11 expression in murine brain.	VLDLR LDLR SORL1	4.50e-08	4	79	3	9726247
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	FLNA ITGBL1 MEGF6 ZNRF3 TNC CCBE1 GPR162 LTBP4 NOTCH1 NOTCH2 ZFPM2	5.75e-08	560	79	11	21653829
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SEL1L CSDE1 ERO1A L1CAM LRP4 NID1 RELA CD46 EXOSC7 LRP1B LDLR NOTCH1 NOTCH2 CRTAP SORL1	7.38e-08	1201	79	15	35696571
Pubmed	Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.	LRP2 LRP4 SORL1	1.12e-07	5	79	3	19047013
Pubmed	Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.	VLDLR LRP2 LDLR	1.12e-07	5	79	3	18685438
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	VLDLR LRP2 LRP1B LDLR NOTCH1 NOTCH2	1.21e-07	101	79	6	23382219
Pubmed	Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.	VLDLR NOTCH1 NOTCH2	2.24e-07	6	79	3	18957219
Pubmed	Cloning and expression analysis of the mouse stroma marker Snep encoding a novel nidogen domain protein.	SNED1 TNC NID1	3.92e-07	7	79	3	15162516
Pubmed	The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.	VLDLR LRP2 LDLR	3.92e-07	7	79	3	12169628
Pubmed	Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.	VLDLR LDLR SORL1	9.38e-07	9	79	3	20005821
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FLNA FLNC PNPLA6 MEGF6 ZNRF3 NLRX1 L1CAM NSD1 LRP4 LTBP4 LDLR NOTCH1 NOTCH2	1.19e-06	1105	79	13	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	PJA2 VLDLR PNPLA6 ZNRF3 LRP2 LRP4 SIK3 LTBP4 KAT14 LDLR ZFP82 NOTCH2 SORL1	1.32e-06	1116	79	13	31753913
Pubmed	Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice.	TNC NCAN L1CAM	1.34e-06	10	79	3	9184108
Pubmed	Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin.	TNC LAMA3 NID1 RELA	1.72e-06	38	79	4	27653694
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP2 LRP4 LRP1B	1.84e-06	11	79	3	24639464
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	SEL1L TNC LAMA3 LDLR CRTAP SORL1	2.10e-06	164	79	6	32409323
Pubmed	Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.	VLDLR LRP2 LRP1B	4.03e-06	14	79	3	15082773
Pubmed	Stage-specific association of apolipoprotein A-I and E in developing mouse retina.	VLDLR LRP2 LDLR	4.03e-06	14	79	3	17389516
Pubmed	Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitecture.	NOTCH1 NOTCH2	5.09e-06	2	79	2	24508387
Pubmed	The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth.	NCAN L1CAM	5.09e-06	2	79	2	7513709
Pubmed	Notch controls generation and function of human effector CD8+ T cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	23380742
Pubmed	A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.	VLDLR LDLR	5.09e-06	2	79	2	19393635
Pubmed	Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers.	NOTCH1 NOTCH2	5.09e-06	2	79	2	21466361
Pubmed	Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.	NOTCH1 NOTCH2	5.09e-06	2	79	2	20069650
Pubmed	Testosterone influenced the expression of Notch1, Notch2 and Jagged1 induced by lipopolysaccharide in macrophages.	NOTCH1 NOTCH2	5.09e-06	2	79	2	15625786
Pubmed	Expression and immunolocalisation of the endocytic receptors megalin and cubilin in the human yolk sac and placenta across gestation.	LRP2 CUBN	5.09e-06	2	79	2	23978537
Pubmed	Polymorphisms in LRP2 and CUBN genes and their association with serum vitamin D levels and sleep apnea.	LRP2 CUBN	5.09e-06	2	79	2	38008818
Pubmed	Megalin and cubilin in the human gallbladder epithelium.	LRP2 CUBN	5.09e-06	2	79	2	18791690
Pubmed	Agonistic anti-TIGIT treatment inhibits T cell responses in LDLr deficient mice without affecting atherosclerotic lesion development.	TIGIT LDLR	5.09e-06	2	79	2	24376654
Pubmed	Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation.	NOTCH1 NOTCH2	5.09e-06	2	79	2	17261636
Pubmed	Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissues.	NOTCH1 NOTCH2	5.09e-06	2	79	2	8440332
Pubmed	Megalin and cubilin: multifunctional endocytic receptors.	LRP2 CUBN	5.09e-06	2	79	2	11994745
Pubmed	Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins.	LRP2 CUBN	5.09e-06	2	79	2	10766831
Pubmed	Cubilin and megalin expression and their interaction in the rat intestine: effect of thyroidectomy.	LRP2 CUBN	5.09e-06	2	79	2	11595644
Pubmed	Acute endotoxemia in mice induces downregulation of megalin and cubilin in the kidney.	LRP2 CUBN	5.09e-06	2	79	2	22437417
Pubmed	Differential expression of Notch1 and Notch2 in developing and adult mouse brain.	NOTCH1 NOTCH2	5.09e-06	2	79	2	7609614
Pubmed	Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.	NOTCH1 NOTCH2	5.09e-06	2	79	2	33017398
Pubmed	Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	21285514
Pubmed	Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.	NOTCH1 NOTCH2	5.09e-06	2	79	2	18353145
Pubmed	Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation.	NOTCH1 NOTCH2	5.09e-06	2	79	2	22205705
Pubmed	Notch signaling induces cell cycle arrest in small cell lung cancer cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	11306509
Pubmed	Correlation of asymmetric Notch2 expression and mouse incisor rotation.	NOTCH1 NOTCH2	5.09e-06	2	79	2	10704869
Pubmed	Notch signaling is necessary but not sufficient for differentiation of dendritic cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	12907456
Pubmed	Inflammatory cytokines induce NOTCH signaling in nucleus pulposus cells: implications in intervertebral disc degeneration.	NOTCH1 NOTCH2	5.09e-06	2	79	2	23589286
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	5.09e-06	2	79	2	7689010
Pubmed	Inhibition of granulocytic differentiation by mNotch1.	NOTCH1 NOTCH2	5.09e-06	2	79	2	8917536
Pubmed	Functional conservation of Notch1 and Notch2 intracellular domains.	NOTCH1 NOTCH2	5.09e-06	2	79	2	15897231
Pubmed	Synergistic association of Notch and NFκB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma.	RELA NOTCH1	5.09e-06	2	79	2	25257945
Pubmed	Increased surface expression of NOTCH on memory T cells in peripheral blood from patients with asthma.	NOTCH1 NOTCH2	5.09e-06	2	79	2	30296524
Pubmed	Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	12753746
Pubmed	Mapping of a defined neurocan binding site to distinct domains of tenascin-C.	TNC NCAN	5.09e-06	2	79	2	9341124
Pubmed	Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL.	NOTCH1 NOTCH2	5.09e-06	2	79	2	26041884
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	5.09e-06	2	79	2	10679933
Pubmed	Notch1 expression, which is related to p65 Status, is an independent predictor of prognosis in colorectal cancer.	RELA NOTCH1	5.09e-06	2	79	2	21771876
Pubmed	The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer.	NOTCH1 NOTCH2	5.09e-06	2	79	2	15492845
Pubmed	Unravelling disparate roles of NOTCH in bladder cancer.	NOTCH1 NOTCH2	5.09e-06	2	79	2	29643502
Pubmed	Effects of Celastrol on growth inhibition of U937 leukemia cells through the regulation of the Notch1/NF-kappaB signaling pathway in vitro.	RELA NOTCH1	5.09e-06	2	79	2	20346213
Pubmed	Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro.	NOTCH1 NOTCH2	5.09e-06	2	79	2	31316119
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	5.09e-06	2	79	2	24469451
Pubmed	Expression and role of cubilin in the internalization of nutrients during the peri-implantation development of the rodent embryo.	LRP2 CUBN	5.09e-06	2	79	2	15616221
Pubmed	A role for notch signaling in human corneal epithelial cell differentiation and proliferation.	NOTCH1 NOTCH2	5.09e-06	2	79	2	17652726
Pubmed	Autophagy is involved in mouse kidney development and podocyte differentiation regulated by Notch signalling.	NPHS1 NOTCH1	5.09e-06	2	79	2	28158917
Pubmed	Clinical role of Notch signaling pathway in intraductal papillary mucinous neoplasm of the pancreas.	NOTCH1 NOTCH2	5.09e-06	2	79	2	25041344
Pubmed	Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	25866967
Pubmed	Xylosyl Extension of O-Glucose Glycans on the Extracellular Domain of NOTCH1 and NOTCH2 Regulates Notch Cell Surface Trafficking.	NOTCH1 NOTCH2	5.09e-06	2	79	2	32423029
Pubmed	Role of megalin and cubilin in the metabolism of vitamin D(3).	LRP2 CUBN	5.09e-06	2	79	2	21595846
Pubmed	Notch2 signaling is required for potent antitumor immunity in vivo.	NOTCH1 NOTCH2	5.09e-06	2	79	2	20351182
Pubmed	Differential distribution of cubilin and megalin expression in the mouse embryo.	LRP2 CUBN	5.09e-06	2	79	2	14983511
Pubmed	Involvement of Notch in activation and effector functions of γδ T cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	24489102
Pubmed	Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.	VLDLR LDLR	5.09e-06	2	79	2	10024503
Pubmed	The Notch pathway in podocytes plays a role in the development of glomerular disease.	NOTCH1 NOTCH2	5.09e-06	2	79	2	18311147
Pubmed	Recurrent mutations of NOTCH genes in follicular lymphoma identify a distinctive subset of tumours.	NOTCH1 NOTCH2	5.09e-06	2	79	2	25141821
Pubmed	Association Analysis of the Cubilin (CUBN) and Megalin (LRP2) Genes with ESRD in African Americans.	LRP2 CUBN	5.09e-06	2	79	2	27197912
Pubmed	LDL receptor deficiency unmasks altered VLDL triglyceride metabolism in VLDL receptor transgenic and knockout mice.	VLDLR LDLR	5.09e-06	2	79	2	11108739
Pubmed	Characterization of the L1-neurocan-binding site. Implications for L1-L1 homophilic binding.	NCAN L1CAM	5.09e-06	2	79	2	10934197
Pubmed	Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein.	LRP2 CUBN	5.09e-06	2	79	2	9334227
Pubmed	Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis.	NOTCH1 NOTCH2	5.09e-06	2	79	2	26933171
Pubmed	A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia.	NOTCH1 NOTCH2	5.09e-06	2	79	2	21693515
Pubmed	Silencing megalin and cubilin genes inhibits myeloma light chain endocytosis and ameliorates toxicity in human renal proximal tubule epithelial cells.	LRP2 CUBN	5.09e-06	2	79	2	18448595
Pubmed	Notch signalling suppresses regulatory T-cell function in murine experimental autoimmune uveitis.	NOTCH1 NOTCH2	5.09e-06	2	79	2	27564686
Pubmed	Notch down-regulation in regenerated epidermis contributes to enhanced expression of interleukin-36α and suppression of keratinocyte differentiation during wound healing.	NOTCH1 NOTCH2	5.09e-06	2	79	2	25982147
Pubmed	Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2.	NOTCH1 NOTCH2	5.09e-06	2	79	2	19701457
Pubmed	Whole Exome Sequencing of Lacrimal Gland Adenoid Cystic Carcinoma.	NOTCH1 NOTCH2	5.09e-06	2	79	2	28820917
Pubmed	Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma.	NOTCH1 NOTCH2	5.09e-06	2	79	2	22006338
Pubmed	Notch1, Notch2, and Epstein-Barr virus-encoded nuclear antigen 2 signaling differentially affects proliferation and survival of Epstein-Barr virus-infected B cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	19339697
Pubmed	Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies.	NOTCH1 NOTCH2	5.09e-06	2	79	2	19915064
Pubmed	Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells.	NOTCH1 NOTCH2	5.09e-06	2	79	2	27776108
Pubmed	Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.	NOTCH1 NOTCH2	5.09e-06	2	79	2	18666240
Pubmed	In vivo mapping of notch pathway activity in normal and stress hematopoiesis.	NOTCH1 NOTCH2	5.09e-06	2	79	2	23791481
Pubmed	Epidermal growth factor regulates NIKS keratinocyte proliferation through Notch signaling.	EGF NOTCH1	5.09e-06	2	79	2	23899513
Pubmed	Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor.	VLDLR LDLR	5.09e-06	2	79	2	8636110
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	COL11A2 TNC NCAN CERT1 NOTCH1 CRTAP	8.69e-06	210	79	6	16537572
Pubmed	Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.	VLDLR LRP2 LDLR	8.98e-06	18	79	3	10827173
Pubmed	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.	VLDLR LRP4 CD46 NOTCH1 LAX1	1.31e-05	132	79	5	26439863
Pubmed	Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.	NPHS1 LRP2 CUBN	1.46e-05	21	79	3	27591083
Pubmed	Combined loss of Hey1 and HeyL causes congenital heart defects because of impaired epithelial to mesenchymal transition.	NOTCH1 NOTCH2 ZFPM2	1.46e-05	21	79	3	17303760
Pubmed	A human MAP kinase interactome.	CSDE1 FLNA FLNC PNLIP JADE2 LAMA3 RELA SIK3	1.50e-05	486	79	8	20936779
Interaction	NTN5 interactions	LRP2 LRP4 LTBP4 LRP1B LDLR NOTCH1 NOTCH2 SORL1	2.71e-14	24	79	8	int:NTN5
Interaction	IGFL3 interactions	VLDLR LRP2 LAMA3 LRP4 LRP1B LDLR NOTCH1 NOTCH2 SORL1	1.39e-11	75	79	9	int:IGFL3
Interaction	ZFP41 interactions	LRP2 LRP4 LTBP4 LRP1B LDLR NOTCH2 SORL1	2.45e-09	57	79	7	int:ZFP41
Interaction	ZNF408 interactions	VLDLR LRP2 LRP4 ZNF317 LTBP4 LRP1B LDLR NOTCH2 SORL1	5.40e-09	145	79	9	int:ZNF408
Interaction	FOXD4L6 interactions	LTBP4 LRP1B LDLR NOTCH1 NOTCH2 SORL1	3.66e-08	49	79	6	int:FOXD4L6
Interaction	ZNF563 interactions	LRP4 LTBP4 LRP1B SORL1	1.06e-07	12	79	4	int:ZNF563
Interaction	IGSF5 interactions	LRP4 LDLR NOTCH1 NOTCH2	2.12e-07	14	79	4	int:IGSF5
Interaction	DEFB123 interactions	LRP4 LRP1B LDLR SORL1	3.84e-07	16	79	4	int:DEFB123
Interaction	CCN6 interactions	LDLR NOTCH1 NOTCH2 SORL1	8.11e-07	19	79	4	int:CCN6
Interaction	ZNF224 interactions	LRP2 LRP4 LRP1B SORL1	1.01e-06	20	79	4	int:ZNF224
Interaction	EGFL6 interactions	LRP2 LRP1B LDLR SORL1	1.24e-06	21	79	4	int:EGFL6
Interaction	TIMP3 interactions	SEL1L LRP2 LRP1B LDLR NOTCH2 SORL1	1.43e-06	90	79	6	int:TIMP3
Interaction	ANKRD36B interactions	VLDLR LRP2 LRP4 LRP1B SORL1	3.76e-06	60	79	5	int:ANKRD36B
Interaction	FEZF1 interactions	LRP2 LRP4 LRP1B SORL1	4.17e-06	28	79	4	int:FEZF1
Interaction	FBXO2 interactions	SNED1 L1CAM LRP2 LAMA3 NID1 LTBP4 LRP1B NOTCH1 NOTCH2 SORL1	4.59e-06	411	79	10	int:FBXO2
Interaction	ZNF517 interactions	LRP2 LTBP4 LRP1B SORL1	4.82e-06	29	79	4	int:ZNF517
Interaction	LRPAP1 interactions	VLDLR JADE2 LRP2 LRP4 LRP1B LDLR SORL1	6.80e-06	180	79	7	int:LRPAP1
Interaction	ZNF74 interactions	LRP4 LTBP4 NOTCH1 SORL1	9.27e-06	34	79	4	int:ZNF74
Interaction	GREM2 interactions	LRP2 LDLR NOTCH2 SORL1	1.31e-05	37	79	4	int:GREM2
Interaction	TAFA3 interactions	CSDE1 LRP2 LRP1B LDLR SORL1	1.37e-05	78	79	5	int:TAFA3
Interaction	ZNF707 interactions	LRP4 LTBP4 NOTCH1 NOTCH2 SORL1	1.46e-05	79	79	5	int:ZNF707
Interaction	RSPO1 interactions	ZNRF3 LRP1B SORL1	2.55e-05	15	79	3	int:RSPO1
Interaction	DKK2 interactions	LRP2 LRP1B NOTCH1 SORL1	4.05e-05	49	79	4	int:DKK2
Interaction	SMOC1 interactions	TRMU TNC NOTCH2 EPHA7	5.96e-05	54	79	4	int:SMOC1
Interaction	CASR interactions	FLNA NOTCH1 NOTCH2	8.46e-05	22	79	3	int:CASR
Interaction	WNT2 interactions	NOTCH1 NOTCH2 SORL1	9.70e-05	23	79	3	int:WNT2
Interaction	PLAT interactions	LAMA3 F2 LRP1B NOTCH2	1.09e-04	63	79	4	int:PLAT
Interaction	ZNF331 interactions	LRP4 LTBP4 LRP1B SORL1	1.09e-04	63	79	4	int:ZNF331
Interaction	NCAN interactions	TNC NCAN L1CAM	1.11e-04	24	79	3	int:NCAN
Interaction	GOLGA8G interactions	LRP4 LDLR SORL1	1.11e-04	24	79	3	int:GOLGA8G
Interaction	GLI4 interactions	LRP2 ZNF317 LRP1B NOTCH2 SORL1	1.32e-04	125	79	5	int:GLI4
Interaction	SHANK3 interactions	GABRG2 FLNA ITGBL1 MEGF6 NCAN GPR162 LTBP4 NOTCH1 NOTCH2	1.38e-04	496	79	9	int:SHANK3
Interaction	ZSCAN21 interactions	LRP4 LRP1B NOTCH2 ZFP62 SORL1	1.48e-04	128	79	5	int:ZSCAN21
Interaction	CNTN1 interactions	TNC L1CAM NOTCH1 NOTCH2	1.56e-04	69	79	4	int:CNTN1
Interaction	CILP interactions	ITGBL1 TNC	2.25e-04	6	79	2	int:CILP
Interaction	MBD1 interactions	MEGF6 TNC LTBP4 NOTCH1	2.38e-04	77	79	4	int:MBD1
Interaction	SLURP1 interactions	LAMA3 SIK3 LDLR NOTCH2 SORL1	2.56e-04	144	79	5	int:SLURP1
Interaction	LGALS1 interactions	FLNA L1CAM LRP2 LDLR NOTCH1 NOTCH2 SORL1	3.25e-04	332	79	7	int:LGALS1
Interaction	SOST interactions	LRP2 LRP4 SORL1	3.47e-04	35	79	3	int:SOST
Interaction	NID2 interactions	TNC NID1 CRTAP EPHA7	3.64e-04	86	79	4	int:NID2
Interaction	DLK2 interactions	LRP2 LDLR NOTCH1	3.77e-04	36	79	3	int:DLK2
Interaction	ZBTB48 interactions	NSD1 LRP2 ZNF317 NOTCH2 ZFP62	3.93e-04	158	79	5	int:ZBTB48
Interaction	WNT10A interactions	LDLR NOTCH1 NOTCH2	4.09e-04	37	79	3	int:WNT10A
Interaction	MDK interactions	LRP2 NID1 NOTCH2 SORL1	4.51e-04	91	79	4	int:MDK
Interaction	VLDLR interactions	SEL1L VLDLR LDLR	4.79e-04	39	79	3	int:VLDLR
Cytoband	8q24.13	KLHL38 ATAD2	1.77e-03	36	79	2	8q24.13
GeneFamily	Low density lipoprotein receptors	VLDLR LRP2 LRP4 LRP1B LDLR	2.73e-10	13	55	5	634
GeneFamily	Fibronectin type III domain containing	NPHS1 SNED1 TNC L1CAM EPHA7 SORL1	8.86e-06	160	55	6	555
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SNED1 NCAN CD46 SVEP1	2.69e-05	57	55	4	1179
Coexpression	NABA_CORE_MATRISOME	SNED1 COL11A2 TNC NCAN LAMA3 NID1 LTBP4 SVEP1	1.58e-06	270	79	8	MM17057
Coexpression	NABA_MATRISOME	HYAL4 SNED1 COL11A2 EGF MEGF6 TNC CCBE1 NCAN LAMA3 NID1 F2 LTBP4 MUC4 SVEP1	1.71e-06	1008	79	14	MM17056
Coexpression	NABA_CORE_MATRISOME	SNED1 COL11A2 TNC NCAN LAMA3 NID1 LTBP4 SVEP1	1.82e-06	275	79	8	M5884
Coexpression	NABA_MATRISOME	HYAL4 SNED1 COL11A2 EGF MEGF6 TNC CCBE1 NCAN LAMA3 NID1 F2 LTBP4 MUC4 SVEP1	2.11e-06	1026	79	14	M5889
Coexpression	NABA_MATRISOME_PRIMARY_METASTATIC_LUNG_TUMOR	TNC CCBE1 NID1 F2	3.73e-06	35	79	4	MM17054
Coexpression	NABA_ECM_GLYCOPROTEINS	SNED1 TNC LAMA3 NID1 LTBP4 SVEP1	2.47e-05	191	79	6	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	SNED1 TNC LAMA3 NID1 LTBP4 SVEP1	2.86e-05	196	79	6	M3008
Coexpression	NABA_MATRISOME_BLEO_FIBROTIC_LUNG	TNC LAMA3 NID1	2.90e-05	20	79	3	MM17053
Coexpression	MAGRANGEAS_MULTIPLE_MYELOMA_IGLL_VS_IGLK_DN	PNPLA6 CD46 LTBP4	5.10e-05	24	79	3	M1420
Coexpression	VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN	EGF F2 NOTCH1 NOTCH2 EPHA7	5.59e-05	135	79	5	M5825
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2C	TNC NCAN FAM181B LRP1B GINS1 NOTCH1 CRTAP	5.70e-05	325	79	7	M39053
Coexpression	MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_DN	LRP4 LTBP4 LDLR LAX1	8.32e-05	76	79	4	M8315
Coexpression	NAKAYA_PLASMACYTOID_DENDRITIC_CELL_FLUMIST_AGE_18_50YO_7DY_DN	GABRG2 FLNC COL11A2 MEGF6 L1CAM CACNA1I ATAD2 GPR162 LTBP4 MUC4 ZNF292	8.62e-05	909	79	11	M41018
Coexpression	NABA_MATRISOME_METASTATIC_LUNG_LYMPH_NODE_METASTASIS	COL11A2 TNC NID1	9.10e-05	29	79	3	MM17055
Coexpression	BOQUEST_STEM_CELL_UP	ITGBL1 TNC AGL LRP1B SVEP1 NOTCH2	1.39e-04	261	79	6	M1834
Coexpression	HU_FETAL_RETINA_FIBROBLAST	SNED1 FLNA NID1 LTBP4 NOTCH2 CRTAP EPHA7	1.63e-04	385	79	7	M39264
Coexpression	ELVIDGE_HYPOXIA_UP	TMEFF1 VLDLR ERO1A ZNF292 SORL1	1.70e-04	171	79	5	M7363
Coexpression	GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN	ZNRF3 L1CAM NSD1 CACNA1I LDLR	1.70e-04	171	79	5	M8820
Coexpression	HOOI_ST7_TARGETS_UP	FLNC MEGF6 CCBE1 CERT1	1.82e-04	93	79	4	M8455
CoexpressionAtlas	kidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_1000	ZCCHC18 VLDLR ZNRF3 TNC L1CAM LRP2 LRP4 CORIN EXOSC7 GINS1 NOTCH1 NOTCH2 EPHA7	5.88e-06	783	79	13	gudmap_kidney_P4_CapMesRenVes_Crym_1000
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLNA TNC LRP4 NID1 LTBP4 SVEP1 NOTCH2	4.64e-08	189	79	7	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ITGBL1 KCNQ5 TNC CCBE1 NID1 ZFPM2	4.81e-08	190	79	7	2e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ITGBL1 KCNQ5 TNC CCBE1 NID1 ZFPM2	4.81e-08	190	79	7	0028f886c789ba238c031eae5d96acaed4af8c25
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	4.98e-08	191	79	7	a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	4.98e-08	191	79	7	8f6d592edc32fdb901af30501d4360512334e8c2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	5.35e-08	193	79	7	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	5.74e-08	195	79	7	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	5.74e-08	195	79	7	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	6.16e-08	197	79	7	6d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ITGBL1 TNC CCBE1 NID1 SVEP1 ZFPM2	6.16e-08	197	79	7	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	6.60e-08	199	79	7	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA ITGBL1 TNC NID1 LTBP4 ZFPM2 EPHA7	6.60e-08	199	79	7	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA TNC LRP4 NID1 LTBP4 ZFPM2 EPHA7	6.60e-08	199	79	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZCCHC18 ITGBL1 KCNQ5 CCBE1 NID1 ZFPM2	3.17e-07	153	79	6	1524557514668f515ac1bbe847611f564b265b42
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CCBE1 NID1 ATAD2 LTBP4 SVEP1 ZFPM2	5.69e-07	169	79	6	a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	8.78e-07	182	79	6	b7d532feb73167e05475855061b35a209583f44c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	8.78e-07	182	79	6	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	8.78e-07	182	79	6	af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	8.78e-07	182	79	6	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 MEGF6 TNC LRP4 ZFPM2 EPHA7	9.06e-07	183	79	6	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SNED1 FLNC PNPLA6 PNLIP MEGF6 ZFPM2	9.06e-07	183	79	6	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	9.35e-07	184	79	6	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 LRP4 NID1 LTBP4 SVEP1 CRTAP	9.65e-07	185	79	6	eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 LRP4 NID1 LTBP4 SVEP1 CRTAP	9.65e-07	185	79	6	f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 LRP4 NID1 LTBP4 SVEP1 CRTAP	9.65e-07	185	79	6	ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 LRP2 NID1 LTBP4 SVEP1 ZFPM2	1.03e-06	187	79	6	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 LRP2 NID1 LTBP4 SVEP1 ZFPM2	1.03e-06	187	79	6	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGBL1 LRP2 NID1 LTBP4 SVEP1 ZFPM2	1.03e-06	187	79	6	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	VLDLR TNC LRP4 NID1 LTBP4 SVEP1	1.06e-06	188	79	6	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.09e-06	189	79	6	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.09e-06	189	79	6	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	KCNQ5 TNC LAMA3 LRP4 LTBP4 NOTCH1	1.13e-06	190	79	6	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ITGBL1 KCNQ5 TNC CORIN ZFPM2	1.13e-06	190	79	6	562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ITGBL1 KCNQ5 TNC CORIN ZFPM2	1.13e-06	190	79	6	f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.16e-06	191	79	6	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 TNC LRP4 SVEP1 NOTCH2 ZFPM2	1.16e-06	191	79	6	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.16e-06	191	79	6	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.16e-06	191	79	6	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.20e-06	192	79	6	bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.20e-06	192	79	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.20e-06	192	79	6	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.20e-06	192	79	6	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.20e-06	192	79	6	0ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 MEGF6 NID1 LTBP4 SVEP1 ZFPM2	1.24e-06	193	79	6	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.27e-06	194	79	6	81713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.27e-06	194	79	6	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.27e-06	194	79	6	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.27e-06	194	79	6	e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.27e-06	194	79	6	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.27e-06	194	79	6	627cffe2d448e74fc5df92e74e5b922a73304137
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.31e-06	195	79	6	d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SNED1 ITGBL1 NID1 LTBP4 SVEP1 ZFPM2	1.31e-06	195	79	6	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.31e-06	195	79	6	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLNA ITGBL1 CCBE1 LTBP4 SVEP1 ZFPM2	1.31e-06	195	79	6	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNC CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.31e-06	195	79	6	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.35e-06	196	79	6	a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCell	COPD-Stromal-Myofibroblast\|COPD / Disease state, Lineage and Cell class	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	1.35e-06	196	79	6	af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.35e-06	196	79	6	3e6803587d8566fd08cb8b290be3b6461743d79c
ToppCell	nucseq-Mesenchymal-Fibroblastic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.35e-06	196	79	6	7d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC NID1 LTBP4 SVEP1 ZFPM2	1.39e-06	197	79	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	COPD-Stromal-Myofibroblast\|World / Disease state, Lineage and Cell class	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	1.39e-06	197	79	6	d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell	PND03-Mesenchymal\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VLDLR FLNA TNC NID1 LTBP4 CRTAP	1.39e-06	197	79	6	e3053ef8f604b6892c21c03e12612b49d3d30f23
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.39e-06	197	79	6	ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC NID1 LTBP4 SVEP1 ZFPM2	1.39e-06	197	79	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.39e-06	197	79	6	37f6b6f2809b952382eaebb642b0aad6371f4251
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.39e-06	197	79	6	b349f8e96d61a4c296af64711e11fc44459a9413
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 ITGBL1 TNC NID1 SVEP1 ZFPM2	1.39e-06	197	79	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC CCBE1 NID1 LTBP4 SVEP1	1.39e-06	197	79	6	c2e390653d5dee7e731c1840cfdab41987dede9b
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC NID1 SVEP1 NOTCH2 ZFPM2	1.43e-06	198	79	6	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	nucseq-Mesenchymal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ITGBL1 CCBE1 NID1 LTBP4 SVEP1 ZFPM2	1.43e-06	198	79	6	8f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	1.48e-06	199	79	6	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	FLNA TNC LRP4 NID1 LTBP4 ZFPM2	1.52e-06	200	79	6	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA ITGBL1 TNC NID1 LTBP4 ZFPM2	1.52e-06	200	79	6	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SNED1 ITGBL1 CCBE1 NID1 SVEP1 ZFPM2	1.52e-06	200	79	6	b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FLNA TNC LRP4 NID1 LTBP4 ZFPM2	1.52e-06	200	79	6	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	FLNA TNC LRP4 NID1 LTBP4 ZFPM2	1.52e-06	200	79	6	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	1.52e-06	200	79	6	07641f476cb1a131c2a50258b88cc13bb38c8379
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	1.52e-06	200	79	6	343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ITGBL1 TNC CCBE1 NID1 LTBP4 SVEP1	1.52e-06	200	79	6	d0c00cdd52c2e001aec9b935f4e981ba77d0386a
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	ITGBL1 TNC CCBE1 CORIN NID1 LTBP4	1.52e-06	200	79	6	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNQ5 LRP4 ATAD2 LTBP4 ZFP82	5.09e-06	140	79	5	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 LRP2 LAMA3 KMO ZFPM2	9.16e-06	158	79	5	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 LRP2 LAMA3 KMO ZFPM2	9.16e-06	158	79	5	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 EGF INSYN1 CCBE1 ZFPM2	9.44e-06	159	79	5	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 EGF INSYN1 CCBE1 ZFPM2	9.44e-06	159	79	5	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 EGF INSYN1 CCBE1 ZFPM2	9.44e-06	159	79	5	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L NPHS1 FCGBP PNLIP LRP4	1.00e-05	161	79	5	b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L NPHS1 FCGBP PNLIP LRP4	1.00e-05	161	79	5	f7a89c481f789f624102857be722c95fbeb47595
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEL1L NPHS1 PNLIP CCBE1 LRP4	1.13e-05	165	79	5	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGBL1 TNC CCBE1 NID1 ZFPM2	1.16e-05	166	79	5	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INSYN1 NID1 LTBP4 SVEP1 EPHA7	1.27e-05	169	79	5	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TNC CCBE1 SVEP1 ZFPM2	1.31e-05	170	79	5	fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 TNC CCBE1 SVEP1 ZFPM2	1.31e-05	170	79	5	03044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INSYN1 LRP2 ATAD2 EXOSC7 EPHA7	1.31e-05	170	79	5	4ce81608111b9ee7cb974dad2c182f38db3dcd79
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC NID1 SVEP1 ZFPM2	1.34e-05	171	79	5	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SNED1 TNC NID1 SVEP1 ZFPM2	1.34e-05	171	79	5	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NCAN LRP4 FAM181B ZNRF4 NOTCH1	1.38e-05	172	79	5	55fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGBL1 CCBE1 NID1 LTBP4 ZFPM2	1.50e-05	175	79	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGBL1 CCBE1 LTBP4 SVEP1 ZFPM2	1.50e-05	175	79	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEFF1 PNLIP LRP2 CACNA1I LRP1B	1.54e-05	176	79	5	c6484334187f64cd00cd35e77d8ae436556b4260
Computational	Adhesion molecules.	ITGBL1 TNC NCAN L1CAM LAMA3 NID1	7.83e-05	141	55	6	MODULE_122
Computational	Genes in the cancer module 236.	VLDLR LDLR SORL1	9.80e-05	18	55	3	MODULE_236
Drug	monatepil	LRP2 LRP4 LRP1B LDLR SORL1	4.92e-08	29	79	5	CID000060810
Drug	25-hydroxycholesterol	LRP2 LRP4 CERT1 LRP1B LDLR NOTCH2 SORL1	1.41e-06	160	79	7	CID000065094
Drug	chondroitin sulfate	HYAL4 COL11A2 EGF PNLIP TNC NCAN L1CAM LAMA3 NID1 F2	1.63e-06	413	79	10	CID000024766
Drug	Epi Lovastatin	VLDLR EGF PNLIP LRP2 LRP4 RELA LRP1B LDLR SORL1	2.80e-06	341	79	9	CID000003962
Drug	pitavastatin	LRP2 LRP4 RELA LRP1B LDLR SORL1	2.85e-06	114	79	6	CID005282451
Drug	sodium linoleate	EGF PNLIP LRP2 LRP4 RELA F2 LRP1B LDLR SORL1	2.86e-06	342	79	9	CID000003931
Drug	epicholesterol	VLDLR PNPLA6 EGF PNLIP LRP2 LRP4 RELA F2 LRP1B LDLR SORL1	1.20e-05	636	79	11	CID000000304
Drug	Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A	SEL1L LAMA3 CD46 LDLR NOTCH2 SORL1	1.67e-05	155	79	6	6817_DN
Drug	Rgd Peptide	EGF TNC L1CAM LAMA3 NID1 CD46 F2	1.96e-05	239	79	7	CID000104802
Drug	probucol	VLDLR LRP2 LRP4 LRP1B LDLR SORL1	2.14e-05	162	79	6	CID000004912
Drug	Y 27632	NPHS1 EGF LAMA3 RELA F2	2.70e-05	101	79	5	ctd:C108830
Drug	mangrove	EGF PNLIP LRP2 LRP4 RELA F2 LRP1B LDLR SORL1	3.49e-05	468	79	9	CID000000965
Drug	hyaluronan	HYAL4 COL11A2 EGF TNC NCAN NSD1 LAMA3	3.62e-05	263	79	7	CID000024759
Drug	Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A	NPHS1 JADE2 GPR162 LDLR SVEP1 KMO	4.51e-05	185	79	6	5632_UP
Drug	Calpain inhibitor I	LRP2 LRP4 RELA LRP1B LDLR CRTAP SORL1	5.37e-05	280	79	7	CID000004332
Drug	Monobenzone [103-16-2]; Up 200; 20uM; MCF7; HT_HG-U133A	VLDLR MEGF6 TMPRSS3 LRP4 CACNA1I GPR162	5.55e-05	192	79	6	3391_UP
Drug	ML 7	EGF LAMA3 RELA F2	6.03e-05	61	79	4	ctd:C070571
Disease	pancreatic ductal carcinoma (is_marker_for)	EGF L1CAM TMPRSS3 MUC4	1.80e-05	61	75	4	DOID:3587 (is_marker_for)
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNC	1.91e-05	3	75	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNC	1.91e-05	3	75	2	DOID:0111190 (implicated_via_orthology)
Disease	pre-eclampsia (is_implicated_in)	CORIN CD46 F2	3.48e-05	25	75	3	DOID:10591 (is_implicated_in)
Disease	Glioblastoma	EGF LTBP4 NOTCH1 NOTCH2	5.01e-05	79	75	4	C0017636
Disease	Giant Cell Glioblastoma	EGF LTBP4 NOTCH1 NOTCH2	6.37e-05	84	75	4	C0334588
Disease	Colorectal Carcinoma	FLNC KCNQ5 LRP2 NID1 CD46 CUBN ZNF292 EPHA7 SORL1	7.18e-05	702	75	9	C0009402
Disease	atherosclerosis (implicated_via_orthology)	F2 LDLR	1.33e-04	7	75	2	DOID:1936 (implicated_via_orthology)
Disease	adenocarcinoma (implicated_via_orthology)	NOTCH1 NOTCH2	1.33e-04	7	75	2	DOID:299 (implicated_via_orthology)
Disease	central nervous system cancer (implicated_via_orthology)	NOTCH1 NOTCH2	1.33e-04	7	75	2	DOID:3620 (implicated_via_orthology)
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	LRP4 SIK3 CERT1 LDLR	1.41e-04	103	75	4	EFO_0008595, EFO_0020944
Disease	Intellectual Disability	CSDE1 KCNQ5 CCBE1 NSD1 LRP2 CERT1 ZNF292	1.43e-04	447	75	7	C3714756
Disease	free cholesterol to total lipids in very small VLDL percentage	SIK3 CERT1 LDLR	1.81e-04	43	75	3	EFO_0022290
Disease	Glioblastoma Multiforme	EGF LTBP4 NOTCH1 NOTCH2	1.88e-04	111	75	4	C1621958
Disease	vascular endothelial growth factor A, isoform 121 measurement	VLDLR ZFPM2	2.27e-04	9	75	2	EFO_0020847
Disease	end stage renal disease (biomarker_via_orthology)	NPHS1 LRP2 RELA	2.36e-04	47	75	3	DOID:783 (biomarker_via_orthology)
Disease	fish oil supplement exposure measurement, triglyceride measurement	NCAN SIK3	2.83e-04	10	75	2	EFO_0004530, EFO_0600007
Disease	otitis media (is_marker_for)	RELA MUC4	2.83e-04	10	75	2	DOID:10754 (is_marker_for)
Disease	phospholipids in very small VLDL measurement	SIK3 CERT1 LDLR	3.01e-04	51	75	3	EFO_0022300
Disease	phospholipids in medium VLDL measurement	SIK3 CERT1 LDLR	3.19e-04	52	75	3	EFO_0022154
Disease	Sarcomatoid Renal Cell Carcinoma	L1CAM RELA MUC4 LRP1B	3.24e-04	128	75	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	L1CAM RELA MUC4 LRP1B	3.24e-04	128	75	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	L1CAM RELA MUC4 LRP1B	3.24e-04	128	75	4	C1266044
Disease	Papillary Renal Cell Carcinoma	L1CAM RELA MUC4 LRP1B	3.24e-04	128	75	4	C1306837
Disease	Renal Cell Carcinoma	L1CAM RELA MUC4 LRP1B	3.24e-04	128	75	4	C0007134
Disease	Sensory hearing loss	COL11A2 LRP2	3.45e-04	11	75	2	C1691779
Disease	total lipids in medium VLDL	SIK3 CERT1 LDLR	3.56e-04	54	75	3	EFO_0022153
Disease	vascular endothelial growth factor A measurement	VLDLR ZFPM2	4.14e-04	12	75	2	EFO_0010804
Disease	phospholipids in VLDL measurement	SIK3 CERT1 LDLR	4.63e-04	59	75	3	EFO_0022301
Disease	Malignant neoplasm of skin	RELA NOTCH1 NOTCH2	4.63e-04	59	75	3	C0007114
Disease	Skin Neoplasms	RELA NOTCH1 NOTCH2	4.63e-04	59	75	3	C0037286
Disease	phospholipids in small VLDL measurement	SIK3 CERT1 LDLR	4.86e-04	60	75	3	EFO_0022146
Disease	total lipids in VLDL measurement	SIK3 CERT1 LDLR	4.86e-04	60	75	3	EFO_0022314
Disease	cholangiocarcinoma (biomarker_via_orthology)	TNC MUC4	4.88e-04	13	75	2	DOID:4947 (biomarker_via_orthology)
Disease	Connective Tissue Diseases	COL11A2 NOTCH1	4.88e-04	13	75	2	C0009782
Disease	gallbladder cancer (is_implicated_in)	EGF LRP1B	4.88e-04	13	75	2	DOID:3121 (is_implicated_in)
Disease	free cholesterol in VLDL measurement	SIK3 CERT1 LDLR	5.11e-04	61	75	3	EFO_0022276
Disease	Autistic Disorder	CSDE1 VLDLR EGF NSD1 ZNF292	5.43e-04	261	75	5	C0004352
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	L1CAM RELA MUC4 LRP1B	5.60e-04	148	75	4	C0279702
Disease	triglycerides to total lipids in IDL percentage	SIK3 CERT1 LDLR	5.61e-04	63	75	3	EFO_0022329
Disease	membranous glomerulonephritis (biomarker_via_orthology)	NPHS1 LRP2	5.69e-04	14	75	2	DOID:10976 (biomarker_via_orthology)
Disease	Spastic Paraplegia, Hereditary	PNPLA6 L1CAM	5.69e-04	14	75	2	C0037773
Disease	cholesterol in large VLDL measurement	SIK3 CERT1 LDLR	6.15e-04	65	75	3	EFO_0021902
Disease	cholesterol in very large VLDL measurement	SIK3 CERT1 LDLR	6.15e-04	65	75	3	EFO_0022230
Disease	Neoplasm of uncertain or unknown behavior of bladder	NOTCH1 NOTCH2	6.55e-04	15	75	2	C0496930
Disease	Proteinuria	LRP2 CUBN	6.55e-04	15	75	2	HP_0000093
Disease	Benign neoplasm of bladder	NOTCH1 NOTCH2	6.55e-04	15	75	2	C0154017
Disease	Carcinoma in situ of bladder	NOTCH1 NOTCH2	6.55e-04	15	75	2	C0154091
Disease	Alcohol abuse	GABRG2 F2 LDLR	6.72e-04	67	75	3	C0085762
Disease	cholesterol to total lipids in very small VLDL percentage	SIK3 CERT1 LDLR	6.72e-04	67	75	3	EFO_0022245
Disease	sphingomyelin measurement	ZNRF3 NCAN SIK3 CERT1 LDLR	7.22e-04	278	75	5	EFO_0010118
Disease	triglycerides to total lipids in very small VLDL percentage	SIK3 CERT1 LDLR	7.33e-04	69	75	3	EFO_0022341
Disease	level of triacylglycerol (56:6) in blood serum	NCAN SIK3	7.48e-04	16	75	2	OBA_2020007
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	VLDLR ZFPM2	7.48e-04	16	75	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	Non-alcoholic Fatty Liver Disease	VLDLR F2 LDLR	7.64e-04	70	75	3	C0400966
Disease	Nonalcoholic Steatohepatitis	VLDLR F2 LDLR	7.64e-04	70	75	3	C3241937
Disease	cholesteryl esters to total lipids in very small VLDL percentage	SIK3 CERT1 LDLR	7.96e-04	71	75	3	EFO_0022259
Disease	Amphetamine-Related Disorders	GABRG2 RELA CUBN	9.34e-04	75	75	3	C0236733
Disease	behavioural disinhibition measurement	CACNA1I RELA ZFPM2	9.34e-04	75	75	3	EFO_0006946
Disease	Amphetamine Abuse	GABRG2 RELA CUBN	9.34e-04	75	75	3	C0236807
Disease	Amphetamine Addiction	GABRG2 RELA CUBN	9.34e-04	75	75	3	C0236804
Disease	Carcinoma of bladder	NOTCH1 NOTCH2	9.50e-04	18	75	2	C0699885
Disease	osteochondrodysplasia (is_implicated_in)	FLNA COL11A2	1.06e-03	19	75	2	DOID:2256 (is_implicated_in)
Disease	Nonsyndromic Deafness	COL11A2 TNC TMPRSS3	1.17e-03	81	75	3	C3711374
Disease	Hemorrhage	F2 EPHA7	1.18e-03	20	75	2	C0019080
Disease	cortisol measurement	ZFP42 LDLR	1.18e-03	20	75	2	EFO_0005843
Disease	Neoplasm Invasiveness	EGF RELA NOTCH2 SORL1	1.26e-03	184	75	4	C0027626
Disease	Congenital diaphragmatic hernia	KCNQ5 ZFPM2	1.30e-03	21	75	2	C0235833
Disease	age-related hearing impairment	COL11A2 CCBE1 TMPRSS3 NSD1 ZFPM2	1.43e-03	324	75	5	EFO_0005782
Disease	Kidney Diseases	NPHS1 EGF LRP2	1.48e-03	88	75	3	C0022658
Disease	Sensorineural Hearing Loss (disorder)	COL11A2 LRP2	1.56e-03	23	75	2	C0018784
Disease	venous thromboembolism, tissue plasminogen activator measurement	LRP4 ZFPM2	1.56e-03	23	75	2	EFO_0004286, EFO_0004791
Disease	Malignant neoplasm of breast	FLNA DDX59 EGF RELA SIK3 CUBN NOTCH1 NOTCH2 SORL1	1.58e-03	1074	75	9	C0006142
Disease	lipid measurement, lipoprotein measurement	NCAN SIK3 LDLR	1.58e-03	90	75	3	EFO_0004529, EFO_0004732
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	ZFP42 EPHA7	1.70e-03	24	75	2	EFO_0004611, EFO_0006329, EFO_0007871
Disease	nephrotic syndrome (biomarker_via_orthology)	NPHS1 VLDLR	1.70e-03	24	75	2	DOID:1184 (biomarker_via_orthology)
Disease	Cerebral Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0750935
Disease	Intracranial Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0750936
Disease	Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0004114
Disease	Grade I Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0205768
Disease	Mixed oligoastrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0547065
Disease	Pilocytic Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0334583
Disease	Juvenile Pilocytic Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0280783
Disease	Diffuse Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0280785
Disease	Childhood Cerebral Astrocytoma	NOTCH1 NOTCH2	1.84e-03	25	75	2	C0338070
Disease	acute necrotizing pancreatitis (biomarker_via_orthology)	RELA CD46	1.99e-03	26	75	2	DOID:0080998 (biomarker_via_orthology)
Disease	level of Sterol ester (27:1/16:0) in blood serum	NCAN LDLR	1.99e-03	26	75	2	OBA_2045191
Disease	brain cancer (implicated_via_orthology)	NOTCH1 NOTCH2	1.99e-03	26	75	2	DOID:1319 (implicated_via_orthology)
Disease	Gemistocytic astrocytoma	NOTCH1 NOTCH2	1.99e-03	26	75	2	C0334581
Disease	Protoplasmic astrocytoma	NOTCH1 NOTCH2	1.99e-03	26	75	2	C0334580
Disease	Fibrillary Astrocytoma	NOTCH1 NOTCH2	1.99e-03	26	75	2	C0334582
Disease	Anaplastic astrocytoma	NOTCH1 NOTCH2	2.15e-03	27	75	2	C0334579
Disease	pancreatic cancer (is_marker_for)	EGF RELA MUC4	2.20e-03	101	75	3	DOID:1793 (is_marker_for)
Disease	obesity (implicated_via_orthology)	PNLIP F2 NOTCH1 NOTCH2	2.22e-03	215	75	4	DOID:9970 (implicated_via_orthology)
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	NCAN SIK3 CERT1 LDLR	2.22e-03	215	75	4	EFO_0008317, EFO_0008591

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKCTSDRNQGEECGY	TBC1D32	76	Q96NH3
EKEAEDGIIAYDDCG	CSDE1	451	O75534
ELAENCVGYCGADIK	ATAD2	626	Q6PL18
GEITKEREDECFSCG	NSD1	2111	Q96L73
KVLYHALCCDDEEGD	INSYN1	191	Q2T9L4
KSEDETEYGCRGSIC	CERT1	56	Q9Y5P4
TFGRYCEGSEDACEE	MUC4	5066	Q99102
CDLSDDAEYECQVGR	NPHS1	101	O60500
GYKGADCTEDVDECA	NOTCH2	406	Q04721
GCADGEESDCLTEYE	PNPLA6	1311	Q8IY17
EGYTGTHCEVDIDEC	NOTCH1	556	P46531
DSGTCLDKIDGYECA	NOTCH1	651	P46531
TRCYCEDGFEITEDG	LRP1B	136	Q9NZR2
CDGQKDCEDGRDEFH	LRP1B	2701	Q9NZR2
LKCNGEYDCADGSDE	LRP1B	3611	Q9NZR2
CDKGFYLDGSDTIVC	CD46	256	P15529
DSCDTCEDGYFALEK	LAMA3	661	Q16787
CDDYAEGRVCKVRFD	GPR162	356	Q16538
GVCTADKDCEDAYRV	TRMU	46	O75648
GKEVCYERLGCFSDD	PNLIP	16	P16233
TDDVYDEKGCQCDVS	KCNQ5	496	Q9NR82
SCEEVEYFCNKGDDE	ZFPM2	56	Q8WW38
CGRYGEYICDKTDED	DDX59	111	Q5T1V6
GLGIEYDEDVVCDVC	JADE2	191	Q9NQC1
FRGDGRTCYDIDECS	NID1	701	P14543
CSDCSADGKEQYERL	KAT14	106	Q9H8E8
IECDDKGDGSCDVRY	FLNC	616	Q14315
AAYESCEQKELECEG	COL11A2	216	P13942
ETYCLLIGGDDGACK	KRT25	381	Q7Z3Z0
RDEGCGDAGDCTSLY	LAX1	231	Q8IWV1
KVGEEDDGEYRCLAE	L1CAM	301	P32004
FVCDGDKDCVDGSDE	LRP2	1166	P98164
SKTFVCDEDNDCGDG	LRP2	3046	P98164
ALDKGCCFEDDETGA	FAM181B	31	A6NEQ2
KTYFSEEDVCGCLEA	NLRX1	441	Q86UT6
FSDKEGSSRCECEDG	EPHA7	301	Q15375
GRGCEDYRCVEVETD	EXOSC7	26	Q15024
ASKYDDCEGGSVARC	CUBN	211	O60494
KDVTCDLIVGCDGAY	KMO	156	O15229
FAGDGKLCSDIDECE	EGF	861	P01133
KLDDGDYLCEDGCQN	FCGBP	641	Q9Y6R7
IECDDKGDGSCDVRY	FLNA	621	P21333
YECLAACEGSREIKD	CRTAP	241	O75718
RECCLSKDDVYDFGA	CACNA1I	291	Q9P0X4
CREGYIREDDGKTCT	CCBE1	161	Q6UXH8
YEGADCREIKTADGC	HYAL4	441	Q2M3T9
DEEYGYECLDGKDCA	GABRG2	401	P18507
TFQCDGDEDCKDGSD	CORIN	396	Q9Y5Q5
GYLDDCTCDVETIDR	ERO1A	41	Q96HE7
GFRGSACEEDVDECA	LTBP4	701	Q8N2S1
GLVYGKFCECDDREC	ITGBL1	171	O95965
YRLSADGCGCEDVDE	MEGF6	401	O75095
YKCDLEDDCGDNSDE	SORL1	1136	Q92673
KEYDECTSDGREDGR	SEL1L	136	Q9UBV2
YGGSFCEKDTEGCDR	NCAN	1076	O14594
YTGCAKCGLELETDE	SHLD2	696	Q86V20
EEDCSCEGAKDGFQD	SIK3	1096	Q9Y2K2
CDEGYRLEGSDKLTC	SVEP1	466	Q4LDE5
LGYTGLKCETDIDEC	SVEP1	1221	Q4LDE5
TGYEGAHCELERDEC	SNED1	781	Q8TER0
KESGCSDTEYGCIAE	CCDC110	31	Q8TBZ0
RCDGVSDCKDGEDEY	TMPRSS3	91	P57727
SDCKDGEDEYRCVRV	TMPRSS3	96	P57727
NDLCAICLDEYEEGD	ZNRF4	306	Q8WWF5
VCDDGYTGEDCRDRQ	TNC	486	P24821
EEDGVYKCDCEGCDR	ZNF292	2251	O60281
REEDNKYCADCEAKG	SMAP1	26	Q8IYB5
CGEQRGEDCAELHDY	TIGIT	211	Q495A1
DDFSDCYIECVIRGE	ZFP42	66	Q96MM3
YECKECGEAFICGAD	ZFP82	226	Q8N141
YCGEEGHSKETCDNE	ZCCHC18	351	P0CG32
SDCAICLEKYIDGEE	ZNRF3	291	Q9ULT6
DSAGERACKCDVYDK	ZNF233	391	A6NK53
EKRYECDDCGGTFRS	ZFP62	166	Q8NB50
CDLNYCEEAVEEETG	F2	286	P00734
ESDVRVCDESSCKYG	TMEFF1	71	Q8IYR6
RCLKDYGEFEVDDGT	GINS1	151	Q14691
VGKDCRDGFYEAELC	RELA	91	Q04206
GSDDLLIKCEEYDGE	PJA2	356	O43164
ERRYECAACGKVFGD	ZNF317	471	Q96PQ6
CKDLVIGYECDCAAG	VLDLR	371	P98155
IGYECDCAAGFELID	VLDLR	376	P98155
CESEEKEDGGGCYDI	AGL	911	P35573
RDYLGDDGLCGEEEK	KLHL38	181	Q2WGJ6
DREYDCKDMSDEVGC	LDLR	256	P01130
YCDGDTDCKDGSDEE	LRP4	166	O75096
GRCILDIYHCDGDDD	LRP4	201	O75096