Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacetylcholine receptor regulator activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

4.41e-1227346GO:0030548
GeneOntologyMolecularFunctionneurotransmitter receptor regulator activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

5.61e-1228346GO:0099602
GeneOntologyMolecularFunctionprotein kinase binding

CD44 SPDYE1 SPDYE21 SPDYE5 SPDYE18 CCDC102B SPDYE2B SPDYE6 SPDYE16 TBC1D14 SPDYE2

1.19e-078733411GO:0019901
GeneOntologyMolecularFunctionkinase binding

CD44 SPDYE1 SPDYE21 SPDYE5 SPDYE18 CCDC102B SPDYE2B SPDYE6 SPDYE16 TBC1D14 SPDYE2

3.39e-079693411GO:0019900
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine phosphatase activity

PTPRA PTPRE

3.77e-0417342GO:0005001
GeneOntologyMolecularFunctiontransmembrane receptor protein phosphatase activity

PTPRA PTPRE

3.77e-0417342GO:0019198
GeneOntologyMolecularFunctionsignaling receptor regulator activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

5.41e-04616346GO:0030545
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

1.47e-1225326GO:0045737
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

3.12e-1228326GO:1904031
GeneOntologyBiologicalProcessregulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

7.13e-0996326GO:0000079
GeneOntologyBiologicalProcessregulation of cyclin-dependent protein kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

9.13e-09100326GO:1904029
GeneOntologyBiologicalProcesspositive regulation of protein serine/threonine kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

4.60e-07193326GO:0071902
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

1.43e-05350326GO:0045860
GeneOntologyBiologicalProcessregulation of protein serine/threonine kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

1.62e-05358326GO:0071900
GeneOntologyBiologicalProcesspositive regulation of kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

3.25e-05405326GO:0033674
GeneOntologyBiologicalProcesspositive regulation of cell cycle

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

3.34e-05407326GO:0045787
GeneOntologyBiologicalProcesspositive regulation of transferase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

9.34e-05490326GO:0051347
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

CD44 SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

9.97e-05724327GO:0001934
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

SPDYE1 TBC1D10B SPDYE5 SPDYE2B SPDYE6 SPDYE16 TBC1D14 SPDYE2

1.34e-041028328GO:0043085
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

CD44 SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

1.58e-04780327GO:0042327
GeneOntologyBiologicalProcessregulation of protein kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

3.10e-04611326GO:0045859
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

CD44 SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

3.29e-04879327GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

CD44 SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

3.29e-04879327GO:0010562
GeneOntologyBiologicalProcesspositive regulation of protein modification process

CD44 SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

4.85e-04937327GO:0031401
GeneOntologyBiologicalProcessregulation of cell cycle

SPDYE1 SPDYE5 ARID1A SPDYE2B PRMT5 SPDYE6 SPDYE16 SPDYE2

5.22e-041256328GO:0051726
GeneOntologyBiologicalProcessregulation of kinase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

5.73e-04686326GO:0043549
GeneOntologyBiologicalProcesspositive regulation of molecular function

SPDYE1 TBC1D10B SPDYE5 SPDYE2B SPDYE6 SPDYE16 TBC1D14 SPDYE2

1.23e-031430328GO:0044093
GeneOntologyBiologicalProcesspositive regulation of oligodendrocyte differentiation

PTPRA PRMT5

1.27e-0334322GO:0048714
GeneOntologyBiologicalProcessregulation of transferase activity

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

1.36e-03810326GO:0051338
GeneOntologyBiologicalProcessregulation of protein phosphorylation

CD44 SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

1.49e-031133327GO:0001932
DomainSpeedy

SPDYE1 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

7.04e-1811327IPR020984
DomainSpy1

SPDYE1 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

7.04e-1811327PF11357
DomainTyr_Pase_rcpt_a/e-type

PTPRA PTPRE

2.84e-062322IPR016336
DomainPTPc

PTPRA PTPRE

1.73e-0336322SM00194
DomainTYR_PHOSPHATASE_PTP

PTPRA PTPRE

2.03e-0339322PS50055
DomainPTPase_domain

PTPRA PTPRE

2.24e-0341322IPR000242
DomainY_phosphatase

PTPRA PTPRE

2.24e-0341322PF00102
DomainTBC

TBC1D10B TBC1D14

3.18e-0349322SM00164
DomainRabGAP-TBC

TBC1D10B TBC1D14

3.71e-0353322PF00566
DomainTBC_RABGAP

TBC1D10B TBC1D14

3.99e-0355322PS50086
DomainRab-GTPase-TBC_dom

TBC1D10B TBC1D14

3.99e-0355322IPR000195
DomainPTPc_motif

PTPRA PTPRE

4.58e-0359322SM00404
DomainTyr_Pase_cat

PTPRA PTPRE

4.58e-0359322IPR003595
DomainTyr_Pase_AS

PTPRA PTPRE

6.93e-0373322IPR016130
DomainTYR_PHOSPHATASE_1

PTPRA PTPRE

9.50e-0386322PS00383
DomainTYR_PHOSPHATASE_2

PTPRA PTPRE

9.72e-0387322PS50056
DomainTYR_PHOSPHATASE_dom

PTPRA PTPRE

9.72e-0387322IPR000387
Domain-

PTPRA PTPRE

1.08e-02923223.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPRA PTPRE

1.24e-0299322IPR029021
DomainIg_E-set

AREL1 TGM7

1.37e-02104322IPR014756
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

4.59e-17934636272447
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

9.35e-161334615611625
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE16 SPDYE2

6.72e-151734615574121
Pubmed

Protein tyrosine phosphatase alpha inhibits hypothalamic leptin receptor signaling and regulates body weight in vivo.

PTPRA PTPRE

9.28e-07234230615487
Pubmed

Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts.

PTPRA PTPRE

9.28e-07234224694598
Pubmed

Tyrosine phosphatases epsilon and alpha perform specific and overlapping functions in regulation of voltage-gated potassium channels in Schwann cells.

PTPRA PTPRE

9.28e-07234216870705
Pubmed

Evolution of the Cdk-activator Speedy/RINGO in vertebrates.

SPDYE6 SPDYE2

2.78e-06334222763696
Pubmed

Identification of a third Protein 4.1 tumor suppressor, Protein 4.1R, in meningioma pathogenesis.

CD44 SPTBN1

2.78e-06334212901833
Pubmed

Tyrosine phosphatase-epsilon activates Src and supports the transformed phenotype of Neu-induced mammary tumor cells.

PTPRA PTPRE

2.78e-06334212598528
Pubmed

Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.

PTPRA PTPRE

2.78e-06334219812040
Pubmed

Membrane localization of the U2 domain of Protein 4.1B is necessary and sufficient for meningioma growth suppression.

CD44 SPTBN1

5.56e-06434215688033
Pubmed

Structural diversity and evolution of human receptor-like protein tyrosine phosphatases.

PTPRA PTPRE

1.39e-0563422170109
Pubmed

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.

PTPRA PTPRE

1.94e-0573421454056
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRA PTPRE

1.94e-05734212376545
Pubmed

Identification of novel protein tyrosine phosphatases of hematopoietic cells by polymerase chain reaction amplification.

PTPRA PTPRE

1.94e-0573421932742
Pubmed

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.

CLGN MBOAT7 PBXIP1 CLCC1

2.61e-0517634428692057
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRA PTPRE

5.07e-05113427832766
Pubmed

OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis.

PRMT5 SPTBN1

5.07e-051134236411454
Pubmed

Bimodal regulation of the PRC2 complex by USP7 underlies tumorigenesis.

PRMT5 SPTBN1

5.07e-051134233849069
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CD44 TBC1D10B PTPRA PTPRE ARID1A CLCC1 SPTBN1

5.87e-05104934727880917
Pubmed

The DNA sequence of human chromosome 7.

SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16

6.58e-0544134512853948
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TGM7 PTPRA FBXL19 PTPRE ARID1A SULT1C3

6.82e-0573034634857952
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

AREL1 CLGN MBOAT7 PBXIP1 CLCC1

8.71e-0546834531056421
Pubmed

Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

PTPRA PTPRE

1.10e-04163428875997
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPRA PTPRE

1.25e-041734219727691
Pubmed

mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.

ARID1A PRMT5

1.41e-041834214559996
Pubmed

Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways.

TBC1D10B TBC1D14

1.93e-042134217562788
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

CD44 MBOAT7 PBXIP1 CLCC1 SPTBN1

2.15e-0456834537774976
Pubmed

Genome-wide association with select biomarker traits in the Framingham Heart Study.

CLGN PTPRE

2.32e-042334217903293
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

CD44 TBC1D10B MBOAT7 PRMT5 SPTBN1 SPDYE16

2.48e-0492534628986522
Pubmed

Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

PTPRA SPTBN1

2.74e-04253428493579
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

CD44 TBC1D10B PTPRA SPTBN1

4.87e-0437734438117590
Pubmed

α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration.

CD44 SPTBN1

5.41e-043534237381005
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

CD44 ARID1A MBOAT7 CLCC1

5.64e-0439234433144569
Pubmed

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

CLGN FBXL19

5.72e-043634224035498
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

TBC1D10B TBC1D14

8.17e-044334217646400
Pubmed

Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.

TBC1D10B TBC1D14

8.17e-044334219077034
Pubmed

Identification of APBB1 as a substrate for anaplastic lymphoma kinase.

MBOAT7 CLCC1

8.55e-044434239115278
CytobandEnsembl 112 genes in cytogenetic band chr7q11

SPDYE21 SPDYE5 SPDYE18 SPDYE16

4.79e-05271344chr7q11
Cytoband7q22.1

SPDYE2B SPDYE6 SPDYE2

8.22e-051133437q22.1
CytobandEnsembl 112 genes in cytogenetic band chr7q22

SPDYE2B SPDYE6 SPDYE2

5.74e-04219343chr7q22
Cytoband7q11.23

SPDYE5 SPDYE18

2.37e-03973427q11.23
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE1 SPDYE5 SPDYE2B SPDYE6 SPDYE2

5.70e-1312195756
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRA PTPRE

2.17e-0421192813
CoexpressionGSE3982_EOSINOPHIL_VS_TH2_UP

CD44 PCNX2 PTPRE MTHFR PBXIP1

4.34e-06195335M5424
CoexpressionGSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP

CD44 CLGN KBTBD4 PBXIP1 PRMT5

4.79e-06199335M3857
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CD44 PCNX2 PGM2L1 PBXIP1

1.32e-05197334de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCellSmart-seq2|World / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SPDYE2B SPDYE6 SPDYE2

1.38e-041363331c831c25ae6fbf0888b8119e22e794c17c59f4d0
ToppCellIIH-CD8-exh_CD4|IIH / Condition, Cell_class and T cell subcluster

FBXL19 SPTBN1 SPDYE16

1.99e-04154333a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCellCOVID-19_Severe-Lymphoid_T/NK-dn_T|COVID-19_Severe / Disease group, lineage and cell class

PGM2L1 PBXIP1 SPTBN1

2.07e-0415633383f25683e0f55472b56f915ee176fc05efc33a31
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PGM2L1 PBXIP1 TBC1D14

2.15e-04158333a38345ffc5a7576ce99212bcbd620864a19de1fc
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-T-cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCNX2 KBTBD4 MBOAT7

2.15e-0415833391d8c93af328c3bbebe1d8f019b94849ebc548c0
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

ARID1A MTHFR PBXIP1

2.31e-04162333810881210e015c788814e4fe8d7a24c929cf2621
ToppCellSevere-Lymphoid-NK-CCR7+_T|Severe / Condition, Lineage, Cell class and cell subclass

CCDC102B PBXIP1 PWP2

2.35e-041633338f0d8c124f1569a5a6bc1db7581989f24d63cca3
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CD44 SPDYE5 PBXIP1

2.48e-041663339fae71b0a42a9b2222453c03e0a1e83f30117ae9
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD44 TBC1D10B PTPRE

2.57e-04168333f45dbcd7753117a3e41e1412bce2100d52fa7fd0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CD44 PGM2L1 PTPRE

3.04e-04178333a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PCNX2 PBXIP1 SPTBN1

3.25e-04182333b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PCNX2 PBXIP1 SPTBN1

3.25e-041823331aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PCNX2 PBXIP1 SPTBN1

3.25e-04182333c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PCNX2 PBXIP1 SPTBN1

3.25e-041823334cb182ef39be2044a6ad7266f332d4177591e550
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

PCNX2 PBXIP1 SPTBN1

3.30e-041833337717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCellnormal_Lung-T/NK_cells-Treg|T/NK_cells / Location, Cell class and cell subclass

CD44 PGM2L1 PBXIP1

3.41e-04185333ea416362d3f06b4a0a7f08c2e5dbbc864f121555
ToppCellPND03|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD44 PTPRE SPTBN1

3.52e-04187333b3fcb36d853adfdea7172c5591de06f027e50af3
ToppCell(1)_T_CD4_reg|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CD44 PGM2L1 PBXIP1

3.63e-0418933328f28672fd260bb2a8d64152737a7242347c3174
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PCNX2 MTHFR CLCC1

3.63e-04189333c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellT_cells-Effector_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CD44 PCNX2 PBXIP1

3.68e-0419033313dc3a0aaa554f63eabac37726bd1f11b66fb3dd
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD44 PTPRE MBOAT7

3.68e-0419033357800d807785b9d539b47945a0a74631f5e88a06
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRE MBOAT7 TBC1D14

3.68e-04190333ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell(1)_T_cells-(1)_T_CD4_reg|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CD44 PGM2L1 PBXIP1

3.68e-04190333ff42af092173c2d4472bb9a02f5a334c272e05a0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CD44 CCDC102B PBXIP1

3.74e-0419133306107849463a1ccb78a5ccd3ae31619ef6bedda3
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD44 PTPRE MBOAT7

3.74e-041913331c7d31684654ca6a046d8cc816af1fdc42369c57
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

3.74e-041913334d7f6216958fb202426b7a102e74682105ce7fca
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

3.74e-04191333e979f6768065b8b3e522d66999ca794d844eccb4
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD44 PTPRE MBOAT7

3.74e-04191333d60d81d2045c6e624bbc8b17e13a32f7921d969f
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CD44 PBXIP1 SPTBN1

3.74e-0419133325dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellControl-Treg|Control / Disease group and Cell class

CD44 PGM2L1 PBXIP1

3.80e-041923333a9a8ac2aa278adde848608f9bb92a002dbb9bcc
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

CD44 PTPRE TBC1D14

3.86e-041933335fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

3.92e-04194333607b5d194ba56efa9b106f10f89368fc103712a0
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PGM2L1 DNAH7 SPTBN1

3.92e-041943335dffa578149104dda33774361e9e77b227b5f1ce
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

3.92e-04194333f5367072b259ae170cf0df3d4d871ab41be29d29
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

3.92e-041943334eef50c38e6edb2ef2cdcd14eb50805f6cd65bc8
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

CD44 PTPRE TBC1D14

3.92e-04194333ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_2-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SPDYE1 PTPRE MBOAT7

3.97e-041953337606b8b40e704bb5447ac57ccf8698794e9c7890
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

CD44 PTPRE MBOAT7

3.97e-04195333ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCellmild-dn_T|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PGM2L1 SPTBN1 CCDC102A

3.97e-04195333158f0f229bad71cc9b06b7399168982bbbbd1d47
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Trm_Th1/Th17|Liver / Manually curated celltypes from each tissue

CD44 PCNX2 PBXIP1

3.97e-04195333480cc62ee1e5b1aaf6b62be6e5afd7a81236a1b0
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

4.03e-041963336230b4a26770d30f1ab83345c087f03be1be0f9e
ToppCellCOVID-19_Convalescent-CD4+_Tcm|COVID-19_Convalescent / Disease condition and Cell class

CD44 PGM2L1 PBXIP1

4.03e-04196333f2a5eeb1cebde2762865ab29792370b751214c4d
ToppCellsevere-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PGM2L1 PBXIP1 SPTBN1

4.03e-0419633314baf176bce5750ef50d6838b748caf68c151e05
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CD44 PTPRE MBOAT7

4.09e-04197333340ce4fef244176fb52e38ffbcbdfda5ac3467dd
ToppCellNS-critical-d_07-13-Myeloid-Neutrophil|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD44 PTPRE MBOAT7

4.09e-04197333f38037dfa6c33e9336130d0cc65eaba0f120efb9
ToppCell10x5'-Liver-Lymphocytic_T_CD4|Liver / Manually curated celltypes from each tissue

CD44 PCNX2 PBXIP1

4.09e-041973334891111894b741555f549deec6af8006376d9358
ToppCell390C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

PTGES2 GPR157 PBXIP1

4.09e-04197333311438418f3d697e54222da111014c887fd815f5
ToppCelldistal-3-Hematologic-IGSF21+_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TGM7 PTPRE TBC1D14

4.09e-0419733352e9dc35dd8cc2605fa4894bb16bb5c6086faa76
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC102B PTPRE SPTBN1

4.16e-041983335d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCellcritical-Myeloid|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CD44 PTPRE MBOAT7

4.16e-04198333a5807517f8ca93b77f49f5787fd9036178b8fc2a
ToppCellNS-critical-d_07-13-Myeloid|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD44 PTPRE MBOAT7

4.16e-0419833308bc3f63a5c5b65bff10aadebdaa5e7f192cda01
ToppCellNS-critical-LOC-Myeloid-Neutrophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD44 PTPRE MBOAT7

4.16e-04198333e56417073e83061a43b9c41d6232d653904c1e90
ToppCellNS-critical-d_0-4-Myeloid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD44 PTPRE MBOAT7

4.16e-0419833372d51284d267f102c26f0ae8279ee9e11e69c7e3
ToppCellNS-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD44 PTPRE MBOAT7

4.16e-0419833358f2bc88d92550fb0b7c2e46c63c49ec6777001c
ToppCellsevere-dn_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PGM2L1 PBXIP1 SPTBN1

4.16e-04198333d4f2213af45ada47e6c62675f468ce05692db507
ToppCellcritical-Myeloid-Neutrophil|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CD44 PTPRE MBOAT7

4.16e-041983334da73dc3acb29d70b160903600d2bf7fdab34333
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC102B PTPRE SPTBN1

4.16e-0419833399d6a64f3410dae3019161feef20a8f06081a24b
ToppCellIPF-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

CD44 PTPRE TBC1D14

4.22e-041993333c2b362d5e824e1a04830e70352f8818de984174
ToppCellILEUM-non-inflamed-(6)_ILC-(6)_ILC3|(6)_ILC / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CD44 MBOAT7 PBXIP1

4.22e-04199333ba144739f65560207303c0143e8de1e86922bebb
ToppCellcritical|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CD44 PTPRE MBOAT7

4.22e-0419933316c55cb8a0e740342009965f0eddfb0ed2858fab
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CD44 CCDC102B SPTBN1

4.22e-04199333212e89d097753790061310373a1fafba773488b6
ToppCellNS-critical|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CD44 PTPRE MBOAT7

4.22e-04199333f7c14dc9a9e659f89352dccf8954d6cbada011ab
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

PGM2L1 PBXIP1 SPTBN1

4.22e-04199333f307d4887b28cf60a591439e278fd668409cb104
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CD44 CCDC102B SPTBN1

4.22e-0419933314b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellControl-Control-Lymphocyte-T/NK-dn_T|Control / Disease, condition lineage and cell class

PGM2L1 PBXIP1 SPTBN1

4.28e-0420033310882c59b7aaf8bd4b5c00aa4ddbb9f7ac5b2cf5
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-dn_T|COVID-19_Severe / Disease, condition lineage and cell class

PGM2L1 PBXIP1 SPTBN1

4.28e-04200333d01aa5fccada22f97d8350ad5888df2aadb5bb1c
ToppCellMS-IIF-Lymphocyte-T/NK-dn_T|IIF / Disease, condition lineage and cell class

PGM2L1 PBXIP1 SPTBN1

4.28e-04200333c34fff02992cba6bcc2308019cb00b94e1227300
Drugpioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A

PCNX2 CLGN PTPRA MBOAT7 DNAH7

6.52e-061973155925_UP
Drug2-(oxalylamino)benzoic acid

PTPRA PTPRE

3.75e-057312ctd:C405943
DrugTg 5

PTGES2 TGM7

1.17e-0412312CID000205491
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A

DNAH7 MTHFR PBXIP1 SPTBN1

1.19e-041883145596_UP
DrugIvermectin [70288-86-7]; Up 200; 4.6uM; MCF7; HT_HG-U133A

CD44 PCNX2 CLGN PTPRA

1.21e-041893147206_UP
Drug2-Chloropyrazine [14508-49-7]; Down 200; 35uM; MCF7; HT_HG-U133A

CD44 PTPRA PTPRE MBOAT7

1.34e-041943143570_DN
Drug0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A

PCNX2 ARID1A PBXIP1 SPTBN1

1.37e-041953143969_UP
DrugFlupentixol dihydrochloride cis-(Z) [2413-38-9]; Up 200; 7.8uM; MCF7; HT_HG-U133A

CD44 PTPRE PBXIP1 SPTBN1

1.40e-041963145307_UP
DrugAmphotericin B [1397-89-3]; Down 200; 4.4uM; HL60; HT_HG-U133A

PTGES2 ARID1A MTHFR SPTBN1

1.40e-041963142441_DN
DrugSulfadimethoxine [122-11-2]; Up 200; 12.8uM; MCF7; HT_HG-U133A

CLGN PTPRA MTHFR SPTBN1

1.40e-041963143441_UP
DrugMetanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A

PTPRE ARID1A MBOAT7 PBXIP1

1.42e-041973141515_DN
DrugEsculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT_HG-U133A

PCNX2 ARID1A DNAH7 SPTBN1

1.42e-041973146310_UP
DrugLaudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; PC3; HT_HG-U133A

PTPRA KBTBD4 MBOAT7 SPTBN1

1.45e-041983147270_DN
DrugSulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A

CLGN MBOAT7 MTHFR SPTBN1

1.45e-041983144839_UP
DrugProglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A

PCNX2 MTHFR PBXIP1 SPTBN1

1.45e-041983143972_UP
DrugCarbetapentane citrate [23142-01-0]; Down 200; 7.6uM; MCF7; HT_HG-U133A

CD44 PCNX2 PTPRA PBXIP1

1.45e-041983142623_DN
DrugNaloxone hydrochloride [357-08-4]; Up 200; 11uM; PC3; HG-U133A

PTGES2 KBTBD4 MBOAT7 PBXIP1

1.45e-041983141924_UP
DrugFlurbiprofen [5104-49-4]; Up 200; 16.4uM; HL60; HT_HG-U133A

CD44 ARID1A MTHFR PBXIP1

1.48e-041993143095_UP
DrugChlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; MCF7; HT_HG-U133A

PCNX2 CLGN ARID1A SPTBN1

1.48e-041993146773_UP
Drugtetraethylenepentamine pentahydrochloride; Up 200; 100uM; MCF7; HG-U133A

CD44 PBXIP1 SPTBN1 PWP2

1.48e-04199314406_UP
DrugParoxetine maleate [64006-44-6]; Down 200; 1uM; MCF7; HT_HG-U133A

CD44 PCNX2 ARID1A SPTBN1

1.51e-042003143904_DN
DrugLynestrenol [52-76-6]; Down 200; 14uM; PC3; HG-U133A

TBC1D10B PTPRE ARID1A SPTBN1

1.51e-042003141953_DN
Drughaloperidol; Up 200; 10uM; MCF7; HG-U133A

PTPRA KBTBD4 PBXIP1 PWP2

1.51e-04200314418_UP
DiseaseMicrosatellite Instability

ARID1A MTHFR

9.72e-0515292C0920269
DiseaseReplication Error Phenotype

ARID1A MTHFR

9.72e-0515292C1721098
Diseasetransitional cell carcinoma (is_implicated_in)

CD44 MTHFR

2.13e-0422292DOID:2671 (is_implicated_in)
Diseasegastric adenocarcinoma (is_marker_for)

PTPRA ARID1A

3.47e-0428292DOID:3717 (is_marker_for)
DiseaseMitral valve prolapse

AREL1 SPTBN1

5.76e-0436292HP_0001634
DiseaseEndometrial Neoplasms

ARID1A MTHFR

1.49e-0358292C0014170
DiseaseArsenic Induced Polyneuropathy

CD44 MTHFR

1.70e-0362292C0751852
DiseaseArsenic Encephalopathy

CD44 MTHFR

1.70e-0362292C0751851
DiseaseArsenic Poisoning

CD44 MTHFR

1.70e-0362292C0311375
DiseaseArsenic Poisoning, Inorganic

CD44 MTHFR

1.70e-0362292C0274861
DiseaseNervous System, Organic Arsenic Poisoning

CD44 MTHFR

1.70e-0362292C0274862
DiseaseEndometrial Carcinoma

ARID1A MTHFR

2.28e-0372292C0476089
DiseaseDermatologic disorders

CD44 MTHFR

2.48e-0375292C0037274
DiseaseHereditary Diffuse Gastric Cancer

CD44 ARID1A MTHFR

2.93e-03293293C1708349
DiseaseStomach Neoplasms

CD44 ARID1A MTHFR

3.04e-03297293C0038356
DiseaseMalignant neoplasm of stomach

CD44 ARID1A MTHFR

3.13e-03300293C0024623

Protein segments in the cluster

PeptideGeneStartEntry
WSRWCYDKRLWPRMD

FBXL19

451

Q6PCT2
VSCNKVEWWWDCLEM

ARID1A

2041

O14497
MFWKDEAFALWIERW

MTHFR

581

P42898
TVEDFWRMIWEWKSH

PTPRE

506

P23469
WFWTKWVRMRKDCNA

PCNX2

1861

A6NKB5
FGWWMFDCWKKNKSR

PGM2L1

361

Q6PCE3
GQKAWDWVHWFLKMR

MBOAT7

391

Q96N66
MDKFWWHAAWGLCLV

CD44

1

P16070
RWSDCTANWREKWSK

CCDC102A

96

Q96A19
WLDHWNWYDLKDCSM

DNAH7

2066

Q8WXX0
WCWIDLEAKDHVLWM

GPR157

156

Q5UAW9
WHFREKVMRWFWTVV

AREL1

726

O15033
WMWWHNFRTLCDYSK

PRMT5

186

O14744
TMRWWSDCTANWREK

CCDC102B

91

Q68D86
LHTIEDFWRMIWEWK

PTPRA

611

P18433
WFDHVKGWWAAKDMH

SULT1C3

181

Q6IMI6
RRMWKCNNATVDWEW

KBTBD4

296

Q9NVX7
EMKWRQWADDWLVHL

PTGES2

231

Q9H7Z7
HRSFCWKRKMEWWDE

SPDYE2B

136

A6NHP3
WKRKMEWWDESEESL

SPDYE2B

141

A6NHP3
EMIDKWEDRWEWLRL

SPTBN1

2001

Q01082
ADHWAADGWRWKIMI

CLGN

436

O14967
KKMDWTGSIWEWFRS

CLCC1

256

Q96S66
QAWEIKHWRKMLWRF

C17orf64

101

Q86WR6
ETMWCSRKVRDLWWQ

TBC1D14

386

Q9P2M4
EKWWDGQRDRKAEHW

PBXIP1

476

Q96AQ6
WDKTVRLWDMFDSWR

PWP2

521

Q15269
HRSFCWKRKREWWDE

SPDYE16

96

A6NNV3
HRSFCWKRKREWWDE

SPDYE18

136

P0DV79
HRSFCWKRKREWWDE

SPDYE21

136

A0A494C086
HRSFCWKRKMEWWDE

SPDYE2

136

Q495Y8
WKRKMEWWDESEESL

SPDYE2

141

Q495Y8
HRSFCWKRKMEWWDE

SPDYE5

136

A6NIY4
WKRKMEWWDESEESL

SPDYE5

141

A6NIY4
HRSFCWKRKMEWWDE

SPDYE6

136

P0CI01
WKRKMEWWDESEESL

SPDYE6

141

P0CI01
HRSFCWKRKMEWWDK

SPDYE1

96

Q8NFV5
RELKWLDMFSNWDKW

TBC1D10B

331

Q4KMP7
HRSFCWKRKREWWDE

nan

96

A6NJR5
RDKIWNFHVWNECWM

TGM7

331

Q96PF1