Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix constituent, lubricant activity

MUC17 MUC3A

3.01e-07452GO:0030197
GeneOntologyMolecularFunctioncargo receptor activity

HAVCR1 SSC5D

1.78e-048552GO:0038024
GeneOntologyMolecularFunctionextracellular matrix structural constituent

MUC17 MUC3A

8.65e-0418852GO:0005201
GeneOntologyMolecularFunctionstructural molecule activity

MUC17 MUC3A

1.82e-0289152GO:0005198
GeneOntologyCellularComponentGolgi lumen

MUC17 MUC3A

2.67e-0410952GO:0005796
GeneOntologyCellularComponentbrush border

MUC17 HAVCR1

5.18e-0415252GO:0005903
GeneOntologyCellularComponentcluster of actin-based cell projections

MUC17 HAVCR1

1.11e-0322352GO:0098862
GeneOntologyCellularComponentapical plasma membrane

MUC17 HAVCR1

5.17e-0348752GO:0016324
GeneOntologyCellularComponentcollagen-containing extracellular matrix

MUC17 SSC5D

6.10e-0353052GO:0062023
GeneOntologyCellularComponentapical part of cell

MUC17 HAVCR1

7.56e-0359252GO:0045177
GeneOntologyCellularComponentextracellular matrix

MUC17 SSC5D

9.23e-0365652GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

MUC17 SSC5D

9.29e-0365852GO:0030312
DomainSEA

MUC17 MUC3A

5.21e-061452SM00200
DomainSEA_dom

MUC17 MUC3A

1.45e-052352IPR000082
DomainSEA

MUC17 MUC3A

1.45e-052352PS50024
DomainEGF

MUC17 MUC3A

1.54e-0323552SM00181
DomainEGF_3

MUC17 MUC3A

1.54e-0323552PS50026
DomainEGF-like_dom

MUC17 MUC3A

1.72e-0324952IPR000742
DomainEGF_1

MUC17 MUC3A

1.81e-0325552PS00022
DomainEGF-like_CS

MUC17 MUC3A

1.89e-0326152IPR013032
DomainEGF_2

MUC17 MUC3A

1.95e-0326552PS01186
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC17 MUC3A

1.21e-051652M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC17 MUC3A

1.37e-051752M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC17 MUC3A

2.54e-052352M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC17 MUC3A

3.26e-052652M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC17 MUC3A

1.89e-046252M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC17 MUC3A

2.27e-046852M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC17 MUC3A

6.05e-0411152M27416
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC17 MUC3A

9.60e-0414052M27484
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC17 MUC3A

1.00e-0314352M27275
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC17 MUC3A

3.02e-0325052M27554
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC17 MUC3A

4.96e-0835210512748
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC17 MUC3A

2.53e-06185218834073
Pubmed

Tet2- and Tet3- Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment.

TET1 HAVCR1

8.72e-06335236522157
CytobandEnsembl 112 genes in cytogenetic band chr7q22

MUC17 MUC3A

2.24e-0421952chr7q22
GeneFamilyCD molecules|Mucins

MUC17 MUC3A

1.28e-052152648
CoexpressionDESCARTES_FETAL_STOMACH_MUC13_DMBT1_POSITIVE_CELLS

MUC17 MUC3A

1.35e-049752M40301
CoexpressionNABA_ECM_AFFILIATED

MUC17 MUC3A

4.13e-0417052M5880
CoexpressionGSE3982_MAC_VS_NKCELL_DN

MUC3A HAVCR1

5.59e-0419852M5509
CoexpressionGSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_UP

TET1 SSC5D

5.71e-0420052M9289
CoexpressionGSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP

TET1 SSC5D

5.71e-0420052M6996
CoexpressionNABA_MATRISOME_ASSOCIATED

MUC17 MUC3A

7.74e-0375152M5885
CoexpressionACEVEDO_METHYLATED_IN_LIVER_CANCER_DN

MUC17 TET1

1.04e-0287352M16009
CoexpressionNABA_MATRISOME

MUC17 MUC3A

1.41e-02102652M5889
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500

TET1 HAVCR1 SSC5D

1.19e-0449253Facebase_RNAseq_e10.5_Maxillary Arch_500
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET1 HAVCR1

1.38e-0416852a007758c219d3d5db2b5529f29af63be0d408304
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TET1 HAVCR1

1.38e-0416852e8878ec68b21c8d5694d7209b816d2f869673164
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC3A HAVCR1

1.43e-04171523a2fefcb62e9d47ae6b3a946c45d3f2dd32c576c
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TET1 HAVCR1

1.46e-04173524f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TET1 HAVCR1

1.46e-04173529bbea566964281f47bf75d665b7d69ba8326e207
ToppCell3'_v3-Lung-Myeloid_Mac-Erythrophagocytic_macrophages|Lung / Manually curated celltypes from each tissue

MUC17 MUC3A

1.54e-0417852b63cee443cc1b7416112bf610d7c9d41e4fa37ed
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC3A

1.56e-0417952859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC3A

1.58e-04180523dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MUC17 MUC3A

1.58e-0418052668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC3A HAVCR1

1.58e-04180528ba9bba0c9fecf184a4332ba4585fb2439f68cd3
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.58e-04180528d9be9cfdf98e5888654a28ab12e5e89f201af00
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC3A HAVCR1

1.61e-0418252e98ca9df33a1a81fc83ecf73d5141a14f2bc985c
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

MUC17 MUC3A

1.63e-041835215d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

MUC17 MUC3A

1.65e-0418452d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.82e-0419352930df79b0600f43617052313294be33bcf5631f0
ToppCell10x5'-GI_small-bowel|World / Manually curated celltypes from each tissue

MUC17 MUC3A

1.82e-0419352cd89dfe53a114078f06343049685883c8e26508f
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.82e-041935232eb026d4317c1499d51294d396dfd5f293f9deb
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.83e-04194522f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCell3'-Child09-12|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.87e-04196521bcc4ffff51cdb6211824686c2422c43b09e24b2
ToppCellEnterocyte|World / shred on cell type and cluster

MUC17 MUC3A

1.89e-04197521dd980fd066aef21694395a4b69df938501d9631
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-0419852e3e2233c796d5e9051c8c1b66f70f406f048ed56
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-04198526e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-0419852222a060c2c63d30da34e4b71c37aa27a048d7d09
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-0419852a76366611f3561fc8aca7d62d1f0a0ea2bef7792
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-0419852c48b3f026b16d48b8eca9f74dc1e3f3f39a89322
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-0419852686d973483d027a3ffa2ad4430ba6e50f3d1378e
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-mature_enterocytic|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-04198528fac96132663f54566136ef54b53684d31dfde32
ToppCell5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-04198528d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCellC_01|World / shred on cell type and cluster

MUC17 MUC3A

1.91e-041985271d38084d09a96331877384ce6346f0de4bdcef9
ToppCell3'-Child09-12-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.91e-04198522967fb2d94662997bfe932ac299c80d6f182fb48
ToppCell3'-Child04-06-SmallIntestine-Epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-0419952ab71b312635a2b2c98d71b60a299f44bc80a3587
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-04199520181c13379f869be47804cdb11bbdabcd30b9b23
ToppCell5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-0419952a5fffe381be1ba7d192b68d1d3937ce47663658e
ToppCell3'-Child09-12-SmallIntestine-Epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-0419952043c65bdf54a1bf0e483fea9ffc042ff5b271764
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-0419952914f66e2b4af323d09fa2340a39cf8051d00a422
ToppCell3'-Child04-06-SmallIntestine-Epithelial-mature_enterocytic|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-0419952ee981046217e8759610eb58a670d98f32cd83abc
ToppCell5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.93e-041995201c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.95e-04200523e13c9a4ba99a7dfbf738b0fb63fb54b4dee5897
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MUC17 MUC3A

1.95e-042005273bfdf068a8ecbefc1e6afe9686df73658ee042f
Drugmucic acid

MUC3A HAVCR1

1.47e-048852CID000000607
Diseasehepatocellular carcinoma (is_marker_for)

TET1 HAVCR1

1.02e-0330152DOID:684 (is_marker_for)
DiseaseHbA1c measurement

TET1 HAVCR1

4.99e-0367552EFO_0004541

Protein segments in the cluster

PeptideGeneStartEntry
LPPTSGTMVTSTTMT

MUC3A

421

Q02505
PFTSMPVSTMPVVTS

MUC17

2221

Q685J3
PMSTPSEVSTPLTIM

MUC17

3626

Q685J3
VPMTTVPTTTVPTTM

HAVCR1

156

Q96D42
VPTTTVPTTMSIPTT

HAVCR1

161

Q96D42
FTTMQPTTMPHPTTT

SSC5D

1266

A1L4H1
VVNTTVVTMPVPMVS

TET1

556

Q8NFU7
VVTMPVPMVSTSSSS

TET1

561

Q8NFU7