Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentnuclear speck

EPAS1 RING1

6.02e-0343162GO:0016607
DomainBHLH

EPAS1 PHTF1

5.74e-0411762PS50888
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

LAT MMP10

5.12e-0332752M27565
CoexpressionGSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN

PHTF1 RING1 MMP10

8.10e-0619663M8420
CoexpressionHAN_SATB1_TARGETS_UP

EPAS1 PHTF1 MMP10

8.16e-0542563M9639
CoexpressionGSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_TCONV_CD4_TCELL_DN

SLC36A2 MMP10

2.59e-0411062M8946
CoexpressionEGFR_UP.V1_UP

EPAS1 MMP10

7.85e-0419262M2634
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_PROXIMAL_BASAL_CELL

EPAS1 MMP10

7.93e-0419362M45706
CoexpressionGSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP

EPAS1 PHTF1

8.10e-0419562M8134
CoexpressionGSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN

LAT PHTF1

8.35e-0419862M4554
CoexpressionGSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN

LAT SLC36A2

8.43e-0419962M6654
CoexpressionGSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN

PHTF1 MMP10

8.43e-0419962M3533
CoexpressionGSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP

LAT RING1

8.43e-0419962M3052
CoexpressionGSE19512_NAUTRAL_VS_INDUCED_TREG_DN

EPAS1 PHTF1

8.52e-0420062M8359
CoexpressionGSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN

LAT EPAS1

8.52e-0420062M7042
CoexpressionGSE2826_XID_VS_BTK_KO_BCELL_DN

LAT EPAS1

8.52e-0420062M4901
CoexpressionGSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_DN

EPAS1 SLC36A2

8.52e-0420062M6270
CoexpressionGSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN

EPAS1 RING1

8.52e-0420062M8688
CoexpressionGSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP

EPAS1 SLC36A2

8.52e-0420062M8484
CoexpressionGSE14350_IL2RB_KO_VS_WT_TEFF_DN

LAT EPAS1

8.52e-0420062M3424
ToppCellPSB-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

6.04e-0591629c61b9f3e9e4f0c9cb242e313d642c2b75705c88
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)|Thalamus / BrainAtlas - Mouse McCarroll V32

LAT SLC36A2

7.44e-05101621d74f6b30d23e942f26fc57665b5c533ff0c089f
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--|Thalamus / BrainAtlas - Mouse McCarroll V32

LAT SLC36A2

7.44e-0510162578946c048084f48a74d4352743017f04039d5e8
ToppCellThalamus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-|Thalamus / BrainAtlas - Mouse McCarroll V32

LAT SLC36A2

7.44e-05101628a3b8abe06a8c5b546ce40c9429401058fe671d7
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

LAT EPAS1

1.60e-0414862c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

LAT EPAS1

1.60e-0414862e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellPND28|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAT EPAS1

1.62e-0414962d3a025440c8ad284a9291c902403e5888d28e90b
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

EPAS1 SLC36A2

1.89e-04161621973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT PHTF1

1.91e-04162625731f9514434296132df4bc86f78ce87b07cdeca
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT PHTF1

1.91e-04162620321fc954ae4ad67ca438cbbc84632562d222188
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

LAT PHTF1

2.03e-0416762c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-CD45____T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.13e-04171621176577841bb6cff27ca288e0c89d2e2242efbb3
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-T_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.16e-04172626c7d03393a60dab954054e34ea842cc77412eb19
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.16e-0417262226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.21e-04174626b362b8a934a4fe6a1dd867b7c448cb3fb3ffd6a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.21e-0417462ecee7e012ccd7876fb9df8aa939f8eb05b0c2b13
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.21e-0417462693fc31bed0f560644e419fa70ef09f863425416
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPAS1 SLC36A2

2.23e-0417562282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAT MMP10

2.23e-0417562e7b0eda141b638f1aad9938aaa76b1ce80171be9
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|metastatic_Brain / Location, Cell class and cell subclass

LAT PHTF1

2.23e-0417562b732c6a423c28856211002107d8c611dcfb6f265
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPAS1 MMP10

2.28e-0417762aadf1d10eccfb014cf3d621b1f01dd6d76df63ac
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

EPAS1 MMP10

2.31e-0417862441d1dba720141891b11f404744c59834d80e6c5
ToppCelldroplet-Lung-nan-18m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.31e-04178628fab75295780e18ee7b4556d66b641c20de10dd2
ToppCelldroplet-Lung-nan-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.31e-0417862730720598c530d2a413ef2a3354ecc66ebb4698c
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EPAS1 MMP10

2.34e-0417962040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAT PHTF1

2.34e-04179626bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAT MMP10

2.36e-041806203e3067ee313e8c40b702b9bc9981f9859d045a2
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC36A2 RING1

2.39e-0418162ebf1ae963a2b22e1772752ed85a4fb0e546d377e
ToppCelldroplet-Limb_Muscle-nan-21m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.44e-0418362ac70a6ec9270b1bfe089702262d4575a6c42afb4
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-mature_NK_T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT EPAS1

2.47e-04184628095be57ed189763b5be039f330149a41e5b406a
ToppCelldroplet-Lung-nan-21m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT EPAS1

2.50e-041856243b7345a61e31099718c9cecf194b4e9884b904b
ToppCelldroplet-Lung-21m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAT EPAS1

2.50e-04185629c907298166e3dd65b1d1e7673a1b8d01b492bd0
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.52e-041866261de94c9ba90e7b6780694199c059c798b1488ae
ToppCelldroplet-Tongue-nan-24m-Myeloid|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT SLC36A2

2.52e-0418662298ea4c7f61df65537dfef171ca81d4e976d89c5
ToppCelldroplet-Tongue-nan-24m-Myeloid-Langerhans_cell|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT SLC36A2

2.52e-04186623e16781b9646de971d953da2c49d4210a4c23fe3
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Proliferating_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAT MMP10

2.63e-041906208420f0ecd2c62e102371d16dcb8eda0d510e92a
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAT MMP10

2.63e-0419062f5a8b44d9948a16e2d5284c78d8f7ed422ac623a
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAT MMP10

2.66e-0419162239300ff76f2c855b2b04d3002461158be90a01b
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

EPAS1 SLC36A2

2.66e-041916278ad7c555409ce1391bce406bc0f3ef575329ece
ToppCellNS-critical-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.69e-041926202b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-Early_cap|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPAS1 MMP10

2.69e-04192624986ef70a665fdfa1df86f7f8a15117487eae159
ToppCell18-Airway-Epithelial-Basal_cell|Airway / Age, Tissue, Lineage and Cell class

EPAS1 MMP10

2.72e-04193625067b0db24f96e26cf3f9437736415f694e7a614
ToppCellcritical-Epithelial-Secretory-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EPAS1 MMP10

2.77e-04195627889818d0f8b8e5c966fbff74b95a28e3fbcc4d2
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPAS1 MMP10

2.77e-04195620be50d5bd0bef2240f7ace8056ce22a6ca2961b9
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EPAS1 MMP10

2.80e-041966281278e696d823744267d6315c4d42799c4ea0b2c
ToppCellNS-moderate-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.80e-04196625d5f3c3e9052b7cdca442e39e73b16ca27a16657
ToppCellkidney_cells-Adult_normal_reference|kidney_cells / Celltypes from Cells and Nuclei per compartment and clinical group

EPAS1 SLC36A2

2.80e-0419662902965bfc5726ca0f1f0a1f6fe3f6d701cc91e6b
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EPAS1 MMP10

2.80e-041966285b697db1c925eff8bbef9d74565c82be5a0ddcc
ToppCellNasal_Brush-Epithelial-Goblet_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

EPAS1 MMP10

2.80e-0419662e16f0831f1f677b28e4a8014f0aede7e713d4f04
ToppCellNasal_Brush-Epithelial-Goblet_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

EPAS1 MMP10

2.80e-041966271e88d9ca28168732bd91f2d4f8f53bb4187963a
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPAS1 MMP10

2.83e-04197625c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellBronchial_Biopsy-Epithelial-Basal_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

EPAS1 MMP10

2.83e-0419762a4855c5aebea4f0fed4eb035844572e82e5bac46
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

EPAS1 MMP10

2.83e-041976278ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellhematopoetic_progenitors-CD34+_MEP_1|hematopoetic_progenitors / Lineage and Cell class

LAT PHTF1

2.83e-04197626172a1b98ff840d9174b1ab20ba0c202a7ef87af
ToppCellBronchial_Brush-Epithelial-Basal_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

EPAS1 MMP10

2.83e-0419762f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCellNS-moderate-d_07-13-Epithelial-Secretory-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.86e-0419862361f3062f73a0add16dd6fbe927698416515879f
ToppCellBronchial_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

EPAS1 MMP10

2.86e-041986210a17d7c116dcd6cf847fe6f5d7196d887cad1f9
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.86e-0419862484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPAS1 MMP10

2.86e-04198625374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.86e-04198624a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

EPAS1 MMP10

2.86e-0419862f5b7013045b61fc56894f80092f799770dde1c8f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPAS1 MMP10

2.89e-04199621e693d7bb481bf03a943b460a69787229625d7b1
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPAS1 MMP10

2.89e-041996294a7867e800df352731796de8c24cba133c29622
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|Control_saline / Treatment groups by lineage, cell group, cell type

LAT PHTF1

2.89e-041996286d4e5dd3bcc6bafa48fd0211dad39a2456b53be
ToppCellmoderate-Epithelial-Secretory-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EPAS1 MMP10

2.91e-04200626f29ef9dcf126c5c19386f6aa9a20c38a2c8ccc8
ToppCellNS-critical-d_07-13-Epithelial-Secretory-diff|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.91e-04200626a76c8e3d937a9c54eb81cab23b8a898f9600de1
ToppCellcritical-Epithelial-Secretory-diff|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

EPAS1 MMP10

2.91e-0420062407465404c5818bd2cd9d489bfbf29c3a55429d4
ToppCellNS-moderate-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.91e-04200628f179b5768fd504af6dd6f6749a0bed7b689e77f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

EPAS1 MMP10

2.91e-0420062b68d212159b9d04866ba02ff55c35be247805eec
ToppCellNS-critical-d_0-4-Epithelial-Secretory-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EPAS1 MMP10

2.91e-0420062047e00f31ca744f82d61cac0e4e66563381f214b
ToppCellBronchus_Control_(B.)-Epithelial-TX-Basal_3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

EPAS1 MMP10

2.91e-042006206b59ee536414d1f73c1e17cdfd7c3f2259b9bef
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal|GW12 / Sample Type, Dataset, Time_group, and Cell type.

EPAS1 PHTF1

2.91e-0420062be83f442179ba4217d12f0458059586ff3130991
DrugLymecycline [992-21-2]; Down 200; 6.6uM; HL60; HT_HG-U133A

LAT EPAS1 PHTF1

1.23e-05196632953_DN
DrugCMCT

LAT MMP10

2.18e-052862CID000084998
DrugMebendazole [31431-39-7]; Up 200; 13.6uM; HL60; HT_HG-U133A

LAT EPAS1

7.05e-04158622338_UP
DrugMethyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; PC3; HT_HG-U133A

EPAS1 MMP10

7.14e-04159624325_UP
DrugPodophyllotoxin [518-28-5]; Up 200; 9.6uM; HL60; HT_HG-U133A

LAT EPAS1

7.77e-04166622540_UP
DrugPyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; MCF7; HT_HG-U133A

LAT EPAS1

7.77e-04166623518_UP
DrugIsotretinoin [4759-48-2]; Up 200; 13.4uM; HL60; HT_HG-U133A

LAT EPAS1

8.06e-04169622407_UP
Drugsarcolysin

LAT SLC36A2

8.34e-0417262CID000004053
DrugPerphenazine [58-39-9]; Up 200; 10uM; PC3; HT_HG-U133A

LAT MMP10

1.02e-03190624637_UP
Drug0179445-0000 [211246-22-9]; Up 200; 10uM; PC3; HT_HG-U133A

LAT MMP10

1.02e-03190623733_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A

LAT EPAS1

1.02e-03190621400_UP
DrugFluocinonide [356-12-7]; Up 200; 8uM; PC3; HT_HG-U133A

EPAS1 MMP10

1.02e-03190624314_UP
Drugclozapine; Down 200; 10uM; HL60; HT_HG-U133A

LAT EPAS1

1.04e-03192626188_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Up 200; 39.2uM; MCF7; HT_HG-U133A

LAT EPAS1

1.05e-03193623870_UP
DrugEstradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A

LAT EPAS1

1.07e-03195622653_UP
DrugFinasteride [98319-26-7]; Down 200; 10.8uM; PC3; HT_HG-U133A

LAT EPAS1

1.07e-03195624300_DN
Drugleukotoxin B (12,13-EODE); Up 200; 0.2uM; MCF7; HT_HG-U133A_EA

EPAS1 PHTF1

1.07e-03195621108_UP
DrugAzlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; HL60; HT_HG-U133A

LAT PHTF1

1.07e-03195622727_DN
DrugFlurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

LAT EPAS1

1.07e-03195626039_UP
DrugNiridazole [61-57-4]; Down 200; 18.6uM; HL60; HT_HG-U133A

LAT EPAS1

1.08e-03196622440_DN
DrugMoxonidine [75438-57-2]; Down 200; 16.6uM; HL60; HT_HG-U133A

LAT EPAS1

1.08e-03196622923_DN
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

LAT MMP10

1.08e-03196625771_UP
DrugAcyclovir [59277-89-3]; Up 200; 17.8uM; PC3; HT_HG-U133A

LAT EPAS1

1.08e-03196624683_UP
DrugMethylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; HL60; HT_HG-U133A

LAT EPAS1

1.08e-03196623040_DN
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Up 200; 9.6uM; PC3; HT_HG-U133A

EPAS1 PHTF1

1.08e-03196622047_UP
DrugScopolamin-N-oxide hydrobromide [6106-81-6]; Up 200; 10uM; MCF7; HT_HG-U133A

LAT EPAS1

1.08e-03196622262_UP
DrugMethazolamide [554-57-4]; Down 200; 17uM; HL60; HT_HG-U133A

LAT EPAS1

1.08e-03196622733_DN
DrugQuinic acid [86-68-0]; Down 200; 19.6uM; HL60; HT_HG-U133A

LAT EPAS1

1.08e-03196622978_DN
DrugSolanine alpha [20562-02-1]; Up 200; 4.6uM; PC3; HT_HG-U133A

LAT MMP10

1.08e-03196624087_UP
DrugDimethadione [695-53-4]; Down 200; 31uM; HL60; HT_HG-U133A

LAT EPAS1

1.08e-03196623029_DN
DrugCanavanine sulfate monohydrate (L,+) [206996-57-8]; Down 200; 13.6uM; HL60; HT_HG-U133A

LAT EPAS1

1.09e-03197622141_DN
DrugLevopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; HL60; HT_HG-U133A

LAT EPAS1

1.09e-03197622980_DN
DrugCarbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A

LAT MMP10

1.09e-03197623299_UP
DrugFluorocurarine chloride [22273-09-2]; Up 200; 11.6uM; MCF7; HT_HG-U133A

LAT EPAS1

1.09e-03197626083_UP
DrugPraziquantel [55268-74-1]; Up 200; 12.8uM; PC3; HT_HG-U133A

EPAS1 MMP10

1.09e-03197625874_UP
DrugGramine [87-52-5]; Down 200; 23uM; PC3; HT_HG-U133A

EPAS1 MMP10

1.09e-03197623999_DN
DrugPHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A

LAT MMP10

1.09e-03197623824_DN
DrugLumicolchicine gamma [6901-14-0]; Up 200; 10uM; PC3; HT_HG-U133A

LAT MMP10

1.10e-03198624195_UP
DrugTiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A

LAT EPAS1

1.10e-03198626013_UP
DrugStreptomycin sulfate [3810-74-0]; Up 200; 2.8uM; PC3; HT_HG-U133A

LAT EPAS1

1.10e-03198625837_UP
DrugTimolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

LAT MMP10

1.10e-03198625645_UP
DrugCarbachol [51-83-2]; Up 200; 21.8uM; PC3; HT_HG-U133A

LAT MMP10

1.10e-03198626742_UP
DrugReserpinic acid hydrochloride; Up 200; 9.2uM; PC3; HT_HG-U133A

LAT EPAS1

1.10e-03198626603_UP
DrugSotalol hydrochloride [959-24-0]; Up 200; 13uM; PC3; HT_HG-U133A

EPAS1 MMP10

1.10e-03198624079_UP
DrugIocetamic acid [16034-77-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A

LAT EPAS1

1.10e-03198624425_UP
DrugPirenperone [ 75444-65-4]; Down 200; 10.2uM; HL60; HT_HG-U133A

LAT EPAS1

1.10e-03198622455_DN
DrugHippeastrine hydrobromide [22352-41-6]; Up 200; 10uM; PC3; HT_HG-U133A

EPAS1 MMP10

1.10e-03198627381_UP
DrugProglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A

LAT MMP10

1.11e-03199624337_UP
DrugAmoxicillin [26787-78-0]; Down 200; 11uM; HL60; HT_HG-U133A

LAT PHTF1

1.11e-03199621265_DN
DrugNoscapine [128-62-1]; Down 200; 9.6uM; HL60; HG-U133A

LAT PHTF1

1.11e-03199621753_DN
DrugTetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; MCF7; HT_HG-U133A

LAT EPAS1

1.11e-03199624159_UP
DrugFlurbiprofen [5104-49-4]; Up 200; 16.4uM; MCF7; HT_HG-U133A

LAT EPAS1

1.13e-03200625634_UP
Drugphenylalanine

EPAS1 PHTF1

1.22e-0320862CID000000994
Drugsodium

LAT SLC36A2 PHTF1

1.29e-0394463CID000000923
DrugFe4S4

SLC36A2 RING1

1.74e-0324962CID000439317
Diseasecancer (implicated_via_orthology)

EPAS1 RING1

1.20e-0326862DOID:162 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CLIIMCEPIQHPSHM

EPAS1

221

Q99814
MMHLAFLVLLCLPVC

MMP10

1

P09238
LPILAMLMALCVHCH

LAT

16

O43561
MLMALCVHCHRLPGS

LAT

21

O43561
SLHSELMCPICLDML

RING1

41

Q06587
LLVMGFIACHCMHIL

SLC36A2

91

Q495M3
PLCLMLLMGTVHCQI

PHTF1

131

Q9UMS5
ILMHLCLLPVCMAHL

nan

71

Q86TA4