Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	heparan sulfate N-deacetylase activity	NDST3 NDST1	2.23e-05	3	55	2	GO:0102140
GeneOntologyMolecularFunction	[heparan sulfate]-glucosamine N-sulfotransferase activity	NDST3 NDST1	4.45e-05	4	55	2	GO:0015016
GeneOntologyMolecularFunction	N-acetylglucosamine deacetylase activity	NDST3 NDST1	4.45e-05	4	55	2	GO:0050119
Domain	HSNSD	NDST3 NDST1	5.28e-05	4	56	2	PF12062
Domain	Heparan_SO4_deacetylase	NDST3 NDST1	5.28e-05	4	56	2	IPR021930
Domain	FF	TCERG1 ARHGAP35	1.31e-04	6	56	2	PF01846
Domain	FF	TCERG1 ARHGAP35	1.31e-04	6	56	2	SM00441
Domain	FF_domain	TCERG1 ARHGAP35	1.31e-04	6	56	2	IPR002713
Domain	FF	TCERG1 ARHGAP35	1.31e-04	6	56	2	PS51676
Domain	Ras_G-nucl-exch_fac_CS	RASGEF1B SOS2	7.85e-04	14	56	2	IPR019804
Domain	RasGEFN	RASGEF1B SOS2	1.62e-03	20	56	2	SM00229
Domain	RasGEF_N	RASGEF1B SOS2	1.79e-03	21	56	2	PF00618
Domain	Ras-like_Gua-exchang_fac_N	RASGEF1B SOS2	1.96e-03	22	56	2	IPR000651
Domain	RASGEF_NTER	RASGEF1B SOS2	1.96e-03	22	56	2	PS50212
Domain	RASGEF	RASGEF1B SOS2	2.74e-03	26	56	2	PS00720
Domain	RASGEF_CAT	RASGEF1B SOS2	3.40e-03	29	56	2	PS50009
Domain	RasGEF	RASGEF1B SOS2	3.64e-03	30	56	2	PF00617
Domain	-	RASGEF1B SOS2	3.64e-03	30	56	2	1.10.840.10
Domain	Ras_GEF_dom	RASGEF1B SOS2	3.64e-03	30	56	2	IPR023578
Domain	RASGEF_cat_dom	RASGEF1B SOS2	3.64e-03	30	56	2	IPR001895
Domain	RasGEF	RASGEF1B SOS2	3.64e-03	30	56	2	SM00147
Domain	SNF2_N	SMARCA1 CHD8	4.13e-03	32	56	2	IPR000330
Domain	SNF2_N	SMARCA1 CHD8	4.13e-03	32	56	2	PF00176
Domain	ConA-like_dom	EYS MAMDC2 RANBP9 ASH2L	4.19e-03	219	56	4	IPR013320
Domain	Sulfotransferase_dom	NDST3 NDST1	5.21e-03	36	56	2	IPR000863
Domain	Sulfotransfer_1	NDST3 NDST1	5.21e-03	36	56	2	PF00685
Domain	DEAH_ATP_HELICASE	SMARCA1 CHD8	5.79e-03	38	56	2	PS00690
Pubmed	Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II.	TCERG1 POLR2A	2.55e-06	2	56	2	10908677
Pubmed	Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication.	TCERG1 POLR2A	2.55e-06	2	56	2	24165037
Pubmed	Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.	SMARCA1 CHD8 ASH2L	2.65e-06	17	56	3	21653943
Pubmed	USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.	SMARCA1 CHD8 ASH2L	3.17e-06	18	56	3	17846119
Pubmed	Hyperphosphorylated C-terminal repeat domain-associating proteins in the nuclear proteome link transcription to DNA/chromatin modification and RNA processing.	TCERG1 POLR2A	7.63e-06	3	56	2	12376575
Pubmed	Functional redundancy of Sos1 and Sos2 for lymphopoiesis and organismal homeostasis and survival.	POLR2A SOS2	7.63e-06	3	56	2	24043312
Pubmed	Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family.	NDST3 NDST1	7.63e-06	3	56	2	9915799
Pubmed	Differential Role of the RasGEFs Sos1 and Sos2 in Mouse Skin Homeostasis and Carcinogenesis.	POLR2A SOS2	7.63e-06	3	56	2	29844066
Pubmed	Ash2L enables P53-dependent apoptosis by favoring stable transcription pre-initiation complex formation on its pro-apoptotic target promoters.	POLR2A ASH2L	7.63e-06	3	56	2	25023704
Pubmed	Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.	NDST3 NDST1	1.52e-05	4	56	2	22049073
Pubmed	Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites.	NDST3 NDST1	1.52e-05	4	56	2	12070138
Pubmed	Heparan Sulfate Proteoglycan Sulfation Regulates Uterine Differentiation and Signaling During Embryo Implantation.	NDST3 NDST1	1.52e-05	4	56	2	29688404
Pubmed	Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses.	NDST3 NDST1	1.52e-05	4	56	2	16056228
Pubmed	Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8.	CHD8 ASH2L	1.52e-05	4	56	2	20085832
Pubmed	Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.	POLR2A ASH2L	2.54e-05	5	56	2	17050672
Pubmed	Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.	NDST3 NDST1	2.54e-05	5	56	2	11087757
Pubmed	CHARGE and Kabuki syndromes: a phenotypic and molecular link.	CHD8 ASH2L	3.80e-05	6	56	2	24705355
Pubmed	Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.	POLR2A SOS2	5.32e-05	7	56	2	30720883
Pubmed	Altered heparan sulfate structure in mice with deleted NDST3 gene function.	NDST3 NDST1	5.32e-05	7	56	2	18385133
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TCERG1 POLR2A SMARCA1 ECPAS PRPF39 ASH2L FOXF1 KIF2C	6.57e-05	857	56	8	25609649
Pubmed	FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling.	NDST3 NDST1	7.09e-05	8	56	2	24067353
Pubmed	Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.	POLR2A ASH2L	9.10e-05	9	56	2	22723415
Pubmed	Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes.	POLR2A ASH2L	1.14e-04	10	56	2	17998332
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NLGN3 DYM PTPRG SAMD13 ARHGAP35 ECPAS TTC3 NXN CDC42EP3 SOS2	1.18e-04	1489	56	10	28611215
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	RANBP9 PLD1 NXN KIF2C	1.35e-04	161	56	4	36398662
Pubmed	Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.	NDST3 NDST1	1.39e-04	11	56	2	15944372
Pubmed	Essential role of Sox2 for the establishment and maintenance of the germ cell line.	TP63 ALPL	1.66e-04	12	56	2	23553930
Pubmed	Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.	NDST3 NDST1	1.66e-04	12	56	2	12460940
Pubmed	Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner.	TCERG1 POLR2A	1.96e-04	13	56	2	10373521
Pubmed	The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing.	TCERG1 POLR2A	1.96e-04	13	56	2	17218272
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JCAD NDST1 TCERG1 RANBP9 PPME1 TTC3 TDP2 ALPL SOS2	1.98e-04	1285	56	9	35914814
Pubmed	Differential gene expression in migratory streams of cortical interneurons.	RASGEF1B CDC42EP3	2.29e-04	14	56	2	22103416
Pubmed	Phosphorylation of BACH1 switches its function from transcription factor to mitotic chromosome regulator and promotes its interaction with HMMR.	POLR2A SCYL1 KIF2C	2.46e-04	75	56	3	29459360
Pubmed	Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.	POLR2A ASH2L	2.64e-04	15	56	2	14992727
Pubmed	Ras signaling is essential for skin development.	TP63 POLR2A	2.64e-04	15	56	2	23831572
Pubmed	Transcription Factor hDREF Is a Novel SUMO E3 Ligase of Mi2α.	RANBP9 TDP2	3.01e-04	16	56	2	27068747
Pubmed	A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.	TCERG1 ASH2L	3.83e-04	18	56	2	29474905
Pubmed	CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription.	TCERG1 POLR2A	3.83e-04	18	56	2	9315662
Pubmed	Development of a deer mouse whole-genome radiation hybrid panel and comparative mapping of Mus chromosome 11 loci.	POLR2A SCN4A	3.83e-04	18	56	2	16416089
Pubmed	IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α.	NLGN3 IGSF21	3.83e-04	18	56	2	28864826
Pubmed	Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development.	NDST3 NDST1	4.75e-04	20	56	2	17107998
Pubmed	NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development.	NDST3 NDST1	5.76e-04	22	56	2	19299468
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	EYS POLR2A INSRR RASGEF1B SCYL1	5.78e-04	420	56	5	28065597
Pubmed	ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification.	TP63 ASH2L	6.30e-04	23	56	2	38582368
Pubmed	The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.	TCERG1 CHD8	7.46e-04	25	56	2	15456888
Pubmed	ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress.	TCERG1 POLR2A	8.07e-04	26	56	2	34162889
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	POLR2A RANBP9 CHD8 ARHGAP35 ECPAS	9.74e-04	472	56	5	38943005
Pubmed	A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development.	TP63 FOXF1	1.01e-03	29	56	2	28797033
Pubmed	Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.	FOXF1 SOS2	1.01e-03	29	56	2	7789972
Pubmed	A human MAP kinase interactome.	TCERG1 RANBP9 CHD8 CDC42EP3 SOS2	1.11e-03	486	56	5	20936779
Pubmed	Integral and associated lysosomal membrane proteins.	CLCN6 DEPDC5 PLD1	1.12e-03	126	56	3	17897319
Pubmed	Identification and characterization of a novel human PP1 phosphatase complex.	POLR2A ASH2L	1.15e-03	31	56	2	20516061
Pubmed	FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme.	TP63 FOXF1	1.15e-03	31	56	2	30153454
Pubmed	Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.	CHD8 ASH2L	1.15e-03	31	56	2	15960975
Pubmed	Role of inflammation gene polymorphisms on pain severity in lung cancer patients.	IL16 IFNAR2	1.30e-03	33	56	2	19773451
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	JCAD POLR2A SCYL1 ECPAS ALPL KIF2C	1.32e-03	754	56	6	35906200
Pubmed	Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos.	CHD8 KIF2C	1.38e-03	34	56	2	7490078
Pubmed	Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.	IL16 IFNAR2	1.55e-03	36	56	2	20811626
Pubmed	ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.	NDST1 TP63 ARHGAP35	1.58e-03	142	56	3	30232004
Interaction	SETD1A interactions	TCERG1 POLR2A INSRR SMARCA1 CHD8 ASH2L	7.55e-06	170	56	6	int:SETD1A
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CLCN6 RASGEF1B UNC13C ALAS2 ALPL	1.46e-06	154	56	5	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CLCN6 RASGEF1B UNC13C ALAS2 ALPL	1.46e-06	154	56	5	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD MAMDC2 UNC13C ALPL	4.12e-05	153	56	4	3b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	JCAD PTPRG NXN FOXF1	4.44e-05	156	56	4	6c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 NDST3 ELOVL3 UNC13C	4.66e-05	158	56	4	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A5 NDST3 ELOVL3 UNC13C	4.66e-05	158	56	4	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NDST3 JCAD NDST1 IGSF21	5.14e-05	162	56	4	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDH20 INSRR TTC3 PNMA8B	5.65e-05	166	56	4	66026988509e39e41274fa0de738383219e8ff30
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	MAMDC2 CPZ CDC42EP3 FOXF1	6.06e-05	169	56	4	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	facs-Lung-nan-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST1 PTPRG FOXF1 KIF2C	6.20e-05	170	56	4	67d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCell	facs-Lung-nan-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST1 PTPRG FOXF1 KIF2C	6.20e-05	170	56	4	8e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	JCAD NLGN3 CPZ FOXF1	6.63e-05	173	56	4	75e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	JCAD NLGN3 CPZ FOXF1	6.63e-05	173	56	4	26e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NDST3 PTPRG MAMDC2 UNC13C	6.78e-05	174	56	4	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NDST3 PTPRG MAMDC2 UNC13C	6.78e-05	174	56	4	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NDST3 PTPRG MAMDC2 UNC13C	6.78e-05	174	56	4	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NDST3 CDH20 UNC13C ALPL	6.78e-05	174	56	4	2947e5906b172d149412fa4e77476fce4ea695d2
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	NDST3 PTPRG MAMDC2 UNC13C	6.78e-05	174	56	4	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NLGN3 MAMDC2 CPZ KIF2C	7.25e-05	177	56	4	3e149bff1f1b393a7abe98984e37981c8296f95d
ToppCell	Healthy-RBC\|Healthy / disease group, cell group and cell class	SLC5A5 CDH20 ALAS2 KIF2C	7.25e-05	177	56	4	945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLGN3 MAMDC2 TESK2 ADAMTS20	8.25e-05	183	56	4	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLGN3 MAMDC2 TESK2 ADAMTS20	8.25e-05	183	56	4	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	LAM-Myeloid-DC\|LAM / Condition, Lineage and Cell class	SERPINB9 CDH20 MAMDC2 IGSF21	9.15e-05	188	56	4	b4140110c2f7d25fd8a0d2749e33e02003ac4bf2
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NDST3 EYS SAMD13 CDC42EP3	9.34e-05	189	56	4	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	IPF-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	SLC5A5 PTPRG NXN ALPL	9.92e-05	192	56	4	356e7a820b744a0ac87352a8d0e6e8d9fa9ed7d2
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NDST3 MAMDC2 UNC13C FOXF1	9.92e-05	192	56	4	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	LAM-Myeloid-DC\|Myeloid / Condition, Lineage and Cell class	SERPINB9 CDH20 MAMDC2 IGSF21	1.01e-04	193	56	4	f665cce40053ae5d6e28f9f70ddf78e8598c9514
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	IL16 RHBDF1 PTPRG MAMDC2	1.03e-04	194	56	4	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS20 POPDC2 TTC3 PNMA8B	1.07e-04	196	56	4	3dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CDH20 UNC13C PLD1 ALPL	1.16e-04	200	56	4	bdda59ffa0496256dd7a5937e88baac5c2a656c3
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CDH20 UNC13C PLD1 ALPL	1.16e-04	200	56	4	dff0be30309b6f5f8757b0378ef05ce97f75dbe8
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B---L4-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CDH20 UNC13C PLD1 ALPL	1.16e-04	200	56	4	c3474e8a03ec4869fd3636a5559d36dd9c5fd414
ToppCell	Neuronal-Excitatory-eB(RORB)-FOLH1B-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CDH20 UNC13C PLD1 ALPL	1.16e-04	200	56	4	5c0c09e7b84fed053b299848bdff63ab842a445c
ToppCell	Neuronal-Excitatory-eB(RORB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CDH20 UNC13C PLD1 ALPL	1.16e-04	200	56	4	51265e30f1138fd79733001d0db759f3dab0aaeb
Disease	autism spectrum disorder (implicated_via_orthology)	NDST3 NDST1 NLGN3 CHD8	1.88e-04	152	55	4	DOID:0060041 (implicated_via_orthology)
Disease	phosphocreatine measurement	ADAMTS20 ALPL	2.63e-04	13	55	2	EFO_0010521
Disease	body fat distribution	DYM PTPRG CPZ CDC42EP3	5.53e-04	202	55	4	EFO_0004341
Disease	azoospermia (implicated_via_orthology)	NDST3 NDST1	1.16e-03	27	55	2	DOID:14227 (implicated_via_orthology)
Disease	Spinocerebellar Ataxia Type 2	SCYL1 TDP2	1.84e-03	34	55	2	C0752121
Disease	Spinocerebellar Ataxia Type 1	SCYL1 TDP2	1.84e-03	34	55	2	C0752120
Disease	Spinocerebellar Ataxia Type 5	SCYL1 TDP2	1.84e-03	34	55	2	C0752123
Disease	Spinocerebellar Ataxia Type 7	SCYL1 TDP2	1.84e-03	34	55	2	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	SCYL1 TDP2	1.84e-03	34	55	2	C0752124
Disease	Ataxia, Spinocerebellar	SCYL1 TDP2	1.84e-03	34	55	2	C0087012
Disease	waist-hip ratio	JCAD NDST1 DYM PTPRG SCN4A ADAMTS20 PLD1 CDC42EP3	1.86e-03	1226	55	8	EFO_0004343

Protein segments in the cluster

Peptide	Gene	Start	Entry
AEDEFVYWPSREESM	PTPRG	1256	P23470
WDEEYPPQMGEEYSQ	BTBD10	321	Q9BSF8
EYDPDTMQFHWDRFR	CHD8	1816	Q9HCK8
SLSEQYPDWPAEDMF	CDC42EP3	191	Q9UKI2
LEERSDMFTWDPYGP	ADAMTS20	841	P59510
WYFEITVDEMPPDTA	ASH2L	421	Q9UBL3
IDWYMDFFPVPSNVT	NDST3	646	O95803
QHPFVFDIEDYMREW	RANBP9	331	Q96S59
FSPVPWSQYFESMED	PPME1	41	Q9Y570
WNLAEVEFSAPYPME	MAMDC2	286	Q7Z304
LFDSFEPETYWDRMH	DEPDC5	1456	O75140
SVIRPDWPYFTDYMT	EYS	1811	Q5T1H1
MDQDFWCPDSYDPSR	JCAD	1341	Q9P266
ARDAWQMTEEEYTPP	ECPAS	916	Q5VYK3
RMDYSFDTTAEDPWV	IL16	701	Q14005
YVRAMTEYWPQEDPD	MPP4	246	Q96JB8
DWYMEFFPIPSNTTS	NDST1	656	P52848
EWTETFPYDFRDERM	RASGEF1B	116	Q0VAM2
PVHFELMSEWERSYF	ALAS2	561	P22557
TETEANFPPEYEKFW	PRPF39	71	Q86UA1
FWLAIDMSFEPPEFE	IFNAR2	126	P48551
SADRDWYSDNEMPPE	ALPL	181	P05186
FMYTDWADRDNPETR	NLGN3	456	Q9NZ94
SFPPRDEWNDFNFDM	TP63	651	Q9H3D4
YPDQSPSEDWTMEER	CLCN6	721	P51797
FQNEVFPEPMFTWTR	IGSF21	366	Q96ID5
PAFDAIDMAWPYFLD	CPZ	131	Q66K79
EEEQPEEFFIPYVWS	DYM	631	Q7RTS9
MRPFFEEYWATSFPI	ELOVL3	26	Q9HB03
YEADMDLWAPPFDSL	CDH20	731	Q9HBT6
DLWAPPFDSLQTYMF	CDH20	736	Q9HBT6
FSASDMYVPDEWEVP	INSRR	961	P14616
QEYDSSFPNWEFARM	KIF2C	221	Q99661
EVEETPEEWNLYYPM	ECSIT	316	Q9BQ95
YWTIDPASEFMFEEG	FOXF1	121	Q12946
QPYEFFSEENSPKWR	SOS2	6	Q07890
PLGEDDFEMFYETWE	SCN4A	1611	P35499
SPEEVMEYSAVFWER	SMARCA1	891	P28370
MWFFARDPVRDFPFE	SCYL1	1	Q96KG9
YFSEMPWLAVPYTDE	NXN	246	Q6DKJ4
DFIDRYSTPRMPWHD	PLD1	666	Q13393
VAYTDPSDPWAREEM	PNMA8B	336	Q9ULN7
IEDMDDHRPFFTYWL	RHBDF1	396	Q96CC6
PDPADWAVMDVVNYF	SAMD13	46	Q5VXD3
PWEEARSFIMNEDFY	ARHGAP35	451	Q9NRY4
AVPEYSLWFEPFVMQ	UNC13C	1681	Q8NB66
WNEPFDETYTREMPF	SERPINB9	171	P50453
FYNPTTRLSMWDRPD	TCERG1	546	O14776
LMDFNPDPRSRYTFW	SLC5A5	231	Q92911
YYEMPDFDVARISPW	POLR2A	1196	P24928
DWEMERALNSYFEPP	TDP2	51	O95551
DPAAYPDMESDIRSW	TTC3	1676	P53804
YIFPYQFMDSPEWES	POPDC2	176	Q9HBU9
MYTPKAEVWDQEFDP	UBR3	851	Q6ZT12
PWFESYRETFLQSMP	TRAPPC8	121	Q9Y2L5
FWMAPEVLRDEPYNE	TESK2	221	Q96S53
PEEMDWSELYPEFFA	METTL1	41	Q9UBP6