Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA uridylyltransferase activity	TUT4 TUT7	5.23e-05	3	84	2	GO:0050265
GeneOntologyMolecularFunction	uridylyltransferase activity	TUT4 TUT7	3.62e-04	7	84	2	GO:0070569
GeneOntologyMolecularFunction	Wnt-protein binding	SFRP4 ROR1 ROR2	3.91e-04	34	84	3	GO:0017147
GeneOntologyBiologicalProcess	pre-miRNA processing	TUT4 AGO1 TUT7	3.96e-05	17	82	3	GO:0031054
GeneOntologyBiologicalProcess	polyuridylation-dependent mRNA catabolic process	TUT4 TUT7	4.67e-05	3	82	2	GO:1990074
Domain	FAM117	FAM117A FAM117B GLCCI1	9.43e-08	3	86	3	PF15388
Domain	Glcci1/FAM117	FAM117A FAM117B GLCCI1	9.43e-08	3	86	3	IPR026642
Domain	NBPF_dom	NBPF9 NBPF11 NBPF14	1.51e-05	11	86	3	IPR010630
Domain	NBPF	NBPF9 NBPF11 NBPF14	1.51e-05	11	86	3	PS51316
Domain	DUF1220	NBPF9 NBPF11 NBPF14	1.51e-05	11	86	3	PF06758
Domain	-	AP1B1 AP2B1	2.10e-05	2	86	2	2.60.40.1150
Domain	Tyr_kinase_rcpt_ROR	ROR1 ROR2	2.10e-05	2	86	2	IPR016247
Domain	Clathrin_b-adaptin_app_Ig-like	AP1B1 AP2B1	2.10e-05	2	86	2	IPR013037
Domain	AP_complex_bsu_1_2_4	AP1B1 AP2B1	6.27e-05	3	86	2	IPR016342
Domain	B2-adapt-app_C	AP1B1 AP2B1	6.27e-05	3	86	2	PF09066
Domain	B-adaptin_app_sub_C	AP1B1 AP2B1	1.25e-04	4	86	2	IPR015151
Domain	B2-adapt-app_C	AP1B1 AP2B1	1.25e-04	4	86	2	SM01020
Domain	Frizzled_dom	SFRP4 ROR1 ROR2	1.78e-04	24	86	3	IPR020067
Domain	FZ	SFRP4 ROR1 ROR2	1.78e-04	24	86	3	PS50038
Domain	Fz	SFRP4 ROR1 ROR2	1.78e-04	24	86	3	PF01392
Domain	Kinase-like_dom	MST1R DST CSNK1G2 PI4KB ROR1 ROR2 CHD9 DMPK MAST2 STK25	1.91e-04	542	86	10	IPR011009
Domain	AP_beta	AP1B1 AP2B1	2.08e-04	5	86	2	IPR026739
Domain	-	DST PLEC	3.11e-04	6	86	2	3.90.1290.10
Domain	Beta2_adaptin/TBP_C_dom	AP1B1 AP2B1	3.11e-04	6	86	2	IPR012295
Domain	-	AP1B1 AP2B1	3.11e-04	6	86	2	3.30.310.10
Domain	Plectin_repeat	DST PLEC	4.34e-04	7	86	2	IPR001101
Domain	PAP_assoc	TUT4 TUT7	4.34e-04	7	86	2	PF03828
Domain	Plectin	DST PLEC	4.34e-04	7	86	2	PF00681
Domain	PAP_assoc	TUT4 TUT7	4.34e-04	7	86	2	IPR002058
Domain	PLEC	DST PLEC	4.34e-04	7	86	2	SM00250
Domain	ZF_CCHC	XRN2 TUT4 TUT7	5.55e-04	35	86	3	PS50158
Domain	Coatomer/calthrin_app_sub_C	AP1B1 AP2B1	5.76e-04	8	86	2	IPR009028
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP1B1 AP2B1	7.39e-04	9	86	2	IPR008152
Domain	Alpha_adaptinC2	AP1B1 AP2B1	7.39e-04	9	86	2	PF02883
Domain	Alpha_adaptinC2	AP1B1 AP2B1	7.39e-04	9	86	2	SM00809
Domain	DUF1220	NBPF9 NBPF11	7.39e-04	9	86	2	SM01148
Domain	NTP_transf_2	TUT4 TUT7	1.12e-03	11	86	2	PF01909
Domain	Polymerase_NTP_transf_dom	TUT4 TUT7	1.12e-03	11	86	2	IPR002934
Domain	Coatomer/clathrin_app_Ig-like	AP1B1 AP2B1	1.34e-03	12	86	2	IPR013041
Domain	ZnF_C2HC	XRN2 TUT4 TUT7	2.08e-03	55	86	3	SM00343
Domain	Znf_CCHC	XRN2 TUT4 TUT7	2.08e-03	55	86	3	IPR001878
Domain	Clathrin/coatomer_adapt-like_N	AP1B1 AP2B1	2.12e-03	15	86	2	IPR002553
Domain	Adaptin_N	AP1B1 AP2B1	2.12e-03	15	86	2	PF01602
Domain	-	CYTH3 CYTH2	2.12e-03	15	86	2	1.10.1000.11
Domain	Sec7	CYTH3 CYTH2	2.12e-03	15	86	2	PF01369
Domain	Sec7_alpha_orthog	CYTH3 CYTH2	2.12e-03	15	86	2	IPR023394
Domain	Sec7	CYTH3 CYTH2	2.41e-03	16	86	2	SM00222
Domain	SEC7	CYTH3 CYTH2	2.41e-03	16	86	2	PS50190
Domain	Sec7_dom	CYTH3 CYTH2	2.41e-03	16	86	2	IPR000904
Domain	Kringle	ROR1 ROR2	2.72e-03	17	86	2	IPR000001
Domain	Kringle_CS	ROR1 ROR2	2.72e-03	17	86	2	IPR018056
Domain	KRINGLE_2	ROR1 ROR2	2.72e-03	17	86	2	PS50070
Domain	Kringle	ROR1 ROR2	2.72e-03	17	86	2	PF00051
Domain	KRINGLE_1	ROR1 ROR2	2.72e-03	17	86	2	PS00021
Domain	KR	ROR1 ROR2	2.72e-03	17	86	2	SM00130
Domain	Actinin_actin-bd_CS	DST PLEC	4.98e-03	23	86	2	IPR001589
Domain	ACTININ_2	DST PLEC	4.98e-03	23	86	2	PS00020
Domain	ACTININ_1	DST PLEC	4.98e-03	23	86	2	PS00019
Domain	zf-CCHC	TUT4 TUT7	4.98e-03	23	86	2	PF00098
Domain	PROTEIN_KINASE_ATP	MST1R CSNK1G2 ROR1 ROR2 DMPK MAST2 STK25	5.24e-03	459	86	7	PS00107
Domain	-	TUT4 TUT7	6.34e-03	26	86	2	4.10.60.10
Domain	Prot_kinase_dom	MST1R CSNK1G2 ROR1 ROR2 DMPK MAST2 STK25	7.33e-03	489	86	7	IPR000719
Domain	PROTEIN_KINASE_DOM	MST1R CSNK1G2 ROR1 ROR2 DMPK MAST2 STK25	7.65e-03	493	86	7	PS50011
Domain	TyrKc	MST1R ROR1 ROR2	7.81e-03	88	86	3	SM00219
Domain	Tyr_kinase_cat_dom	MST1R ROR1 ROR2	7.81e-03	88	86	3	IPR020635
Domain	Spectrin_repeat	DST PLEC	7.85e-03	29	86	2	IPR002017
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2	AP2B1 ROR1 ROR2	2.14e-05	13	61	3	M27415
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF8 NBPF19 NBPF12 NBPF9 NBPF10 NBPF11 NBPF14 NBPF20	4.15e-16	21	94	8	16079250
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF12 NBPF9 NBPF14	1.04e-08	10	94	4	22973535
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF8 NBPF12 NBPF9 NBPF10 CEP192 NBPF11 NBPF14	4.22e-07	170	94	7	23314748
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	HSPG2 DST ZGRF1 ZKSCAN8 SLC10A3 PLEC MAST2 GLCCI1 HP1BP3	6.49e-07	363	94	9	14691545
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	TUT4 GSE1 AP1B1 CSNK1G2 CYTH3 CYTH2 CHTF18 PI4KB ZKSCAN8 NBPF26 CHD9 SLC10A3 BTRC	1.27e-06	925	94	13	28986522
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	NBPF8 NBPF12 DST ABCA13 ZGRF1 NBPF9 NBPF10 NBPF11 NBPF14 HP1BP3	1.33e-06	513	94	10	25798074
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MST1R HSPG2 DST CSNK1G2 CYTH3 LRP3 AKAP13 SENP2 SLC10A3 CEP192 PLEC MBD5 MAST2 DUS1L	1.61e-06	1105	94	14	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FAM117A DST PI4KB ROR2 AKAP13 FAM117B CEP192 PLEC RAB11FIP1 MAST2 DENND2B GLCCI1	3.65e-06	861	94	12	36931259
Pubmed	The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.	TUT4 TUT7	7.23e-06	2	94	2	28665939
Pubmed	Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.	ROR1 ROR2	7.23e-06	2	94	2	11429290
Pubmed	RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell type.	TUT4 TUT7	7.23e-06	2	94	2	34949722
Pubmed	ROR1 and ROR2 expression in pancreatic cancer.	ROR1 ROR2	7.23e-06	2	94	2	34763666
Pubmed	A novel family of cell surface receptors with tyrosine kinase-like domain.	ROR1 ROR2	7.23e-06	2	94	2	1334494
Pubmed	Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2.	ROR1 ROR2	7.23e-06	2	94	2	15654020
Pubmed	Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.	ROR1 ROR2	7.23e-06	2	94	2	25029443
Pubmed	TUT4/7-mediated uridylation of a coronavirus subgenomic RNAs delays viral replication.	TUT4 TUT7	7.23e-06	2	94	2	37085578
Pubmed	TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms.	TUT4 TUT7	7.23e-06	2	94	2	25979828
Pubmed	Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development.	ROR1 ROR2	7.23e-06	2	94	2	11455430
Pubmed	Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion.	ROR1 ROR2	7.23e-06	2	94	2	26515598
Pubmed	Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases.	ROR1 ROR2	7.23e-06	2	94	2	11713269
Pubmed	The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.	ROR1 ROR2	7.23e-06	2	94	2	34155901
Pubmed	Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies.	ROR1 ROR2	7.23e-06	2	94	2	22988987
Pubmed	β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases.	ROR1 ROR2	7.23e-06	2	94	2	26862065
Pubmed	Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes.	CYTH3 CYTH2	7.23e-06	2	94	2	31601460
Pubmed	ROR1 and ROR2 play distinct and opposing roles in endometrial cancer.	ROR1 ROR2	7.23e-06	2	94	2	29395309
Pubmed	Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.	ROR1 ROR2	7.23e-06	2	94	2	37430307
Pubmed	Uridylation by TUT4 and TUT7 marks mRNA for degradation.	TUT4 TUT7	7.23e-06	2	94	2	25480299
Pubmed	Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system.	ROR1 ROR2	7.23e-06	2	94	2	10231392
Pubmed	Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.	ROR1 ROR2	7.23e-06	2	94	2	24104062
Pubmed	Role of the Ror family receptors in Wnt5a signaling.	ROR1 ROR2	7.23e-06	2	94	2	38587578
Pubmed	Terminal Uridylyltransferases TUT4/7 Regulate microRNA and mRNA Homeostasis.	TUT4 TUT7	7.23e-06	2	94	2	36497000
Pubmed	Expression and subcellular localization of Ror tyrosine kinase receptors are developmentally regulated in cultured hippocampal neurons.	ROR1 ROR2	7.23e-06	2	94	2	12898527
Pubmed	3' Uridylation Confers miRNAs with Non-canonical Target Repertoires.	TUT4 TUT7	2.16e-05	3	94	2	31178353
Pubmed	mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome.	TUT4 TUT7	2.16e-05	3	94	2	28792939
Pubmed	Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s.	TUT4 TUT7	2.16e-05	3	94	2	30122351
Pubmed	BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.	DST PLEC	2.16e-05	3	94	2	19932097
Pubmed	Ror1-Ror2 complexes modulate synapse formation in hippocampal neurons.	ROR1 ROR2	2.16e-05	3	94	2	19958813
Pubmed	Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors.	CYTH3 CYTH2	2.16e-05	3	94	2	18042453
Pubmed	TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.	TUT4 TUT7	2.16e-05	3	94	2	36071058
Pubmed	Mono-uridylation of pre-microRNA as a key step in the biogenesis of group II let-7 microRNAs.	TUT4 TUT7	2.16e-05	3	94	2	23063654
Pubmed	Wnt5a induces ROR1/ROR2 heterooligomerization to enhance leukemia chemotaxis and proliferation.	ROR1 ROR2	2.16e-05	3	94	2	26690702
Pubmed	Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling.	CYTH3 CYTH2	2.16e-05	3	94	2	22454518
Pubmed	Dupuytren's contracture-associated SNPs increase SFRP4 expression in non-immune cells including fibroblasts to enhance inflammation development.	SFRP4 BTRC	2.16e-05	3	94	2	36719100
Pubmed	Complex regulation of multiple cytohesin-like genes in murine tissues and cells.	CYTH3 CYTH2	2.16e-05	3	94	2	9744817
Pubmed	Lineage-specific gene duplication and loss in human and great ape evolution.	NBPF19 NBPF9 SRP68 NBPF20	3.78e-05	69	94	4	15252450
Pubmed	Similarities in function and gene structure of cytohesin-4 and cytohesin-1, guanine nucleotide-exchange proteins for ADP-ribosylation factors.	CYTH3 CYTH2	4.32e-05	4	94	2	10652308
Pubmed	Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.	AP1B1 AP2B1	4.32e-05	4	94	2	17290217
Pubmed	The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution.	ROR1 ROR2	4.32e-05	4	94	2	12754255
Pubmed	Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.	TUT4 TUT7	4.32e-05	4	94	2	28671666
Pubmed	Essential role of Wnt5a-Ror1/Ror2 signaling in metanephric mesenchyme and ureteric bud formation.	ROR1 ROR2	4.32e-05	4	94	2	26840931
Pubmed	Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates.	ROR1 ROR2	4.32e-05	4	94	2	28885975
Pubmed	Attenuation of cell adhesion in lymphocytes is regulated by CYTIP, a protein which mediates signal complex sequestration.	CYTH3 CYTH2	4.32e-05	4	94	2	12606567
Pubmed	Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7).	TUT4 TUT7	4.32e-05	4	94	2	22898984
Pubmed	Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.	DST PLEC	4.32e-05	4	94	2	14668477
Pubmed	ATM binds to beta-adaptin in cytoplasmic vesicles.	AP1B1 AP2B1	4.32e-05	4	94	2	9707615
Pubmed	Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.	AP1B1 AP2B1	4.32e-05	4	94	2	7534311
Pubmed	The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.	AP1B1 AP2B1 CTNNA3	4.75e-05	26	94	3	23077317
Pubmed	C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.	CYTH3 CYTH2 BTRC	5.34e-05	27	94	3	29420262
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	XRN2 DST GSE1 AP1B1 CHTF18 TUT7 AKAP13 MAST2 HP1BP3	6.82e-05	650	94	9	38777146
Pubmed	Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains.	CYTH3 CYTH2	7.19e-05	5	94	2	21041639
Pubmed	A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.	TUT4 TUT7	7.19e-05	5	94	2	30617251
Pubmed	Appropriate crypt formation in the uterus for embryo homing and implantation requires Wnt5a-ROR signaling.	ROR1 ROR2	7.19e-05	5	94	2	25043182
Pubmed	Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.	CYTH3 CYTH2	7.19e-05	5	94	2	12920129
Pubmed	Endocytosis of the glucose transporter GLUT8 is mediated by interaction of a dileucine motif with the beta2-adaptin subunit of the AP-2 adaptor complex.	AP1B1 AP2B1	7.19e-05	5	94	2	16723738
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	HSPG2 PRDM8 XRN2 AGO1 DST AP2B1 CAPZA2 GLUL SRP68 PLEC	9.67e-05	844	94	10	25963833
Pubmed	Ror family receptor tyrosine kinases regulate the maintenance of neural progenitor cells in the developing neocortex.	ROR1 ROR2	1.08e-04	6	94	2	22328498
Pubmed	Clathrin.	AP1B1 AP2B1	1.08e-04	6	94	2	10966473
Pubmed	INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling.	CYTH3 CYTH2	1.08e-04	6	94	2	30355448
Pubmed	Sfrp4 repression of the Ror2/Jnk cascade in osteoclasts protects cortical bone from excessive endosteal resorption.	SFRP4 ROR2	1.08e-04	6	94	2	31239337
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	NCAPG AP2B1 CAPZA2 PLEC HP1BP3	1.40e-04	182	94	5	31067453
Pubmed	Progressive impairment of muscle regeneration in muscleblind-like 3 isoform knockout mice.	GLUL DMPK	1.50e-04	7	94	2	23660517
Pubmed	Wnt5a-Ror-Dishevelled signaling constitutes a core developmental pathway that controls tissue morphogenesis.	ROR1 ROR2	1.50e-04	7	94	2	22343533
Pubmed	The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome.	DST PLEC	1.50e-04	7	94	2	10637308
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	NBPF19 AP2B1 NBPF9 AKAP13 PLEC NBPF14 NBPF20	1.71e-04	430	94	7	35044719
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	CYTH2 PI4KB FAM117B DENND2B	1.74e-04	102	94	4	15778465
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	AGO1 DST AP1B1 AP2B1 CEP192 PLEC DMPK GLCCI1 BTRC STK25	1.78e-04	910	94	10	36736316
Pubmed	SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein.	CSNK1G2 BTRC	2.00e-04	8	94	2	15917222
Pubmed	The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.	CYTH3 CYTH2	2.00e-04	8	94	2	17398095
Pubmed	Epidermolysis Bullosa Simplex	DST PLEC	2.00e-04	8	94	2	20301543
Pubmed	Genetic interactions between Ror2 and Wnt9a, Ror1 and Wnt9a and Ror2 and Ror1: Phenotypic analysis of the limb skeleton and palate in compound mutants.	ROR1 ROR2	2.00e-04	8	94	2	30801848
Pubmed	FRMD4A regulates epithelial polarity by connecting Arf6 activation with the PAR complex.	CYTH3 CYTH2	2.00e-04	8	94	2	20080746
Pubmed	A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4.	AP1B1 AP2B1	2.00e-04	8	94	2	9811611
Pubmed	Functional proteomics mapping of a human signaling pathway.	HSPG2 DST AP1B1 INPP4A GLUL PLEC IL1RAP DENND2B	2.05e-04	591	94	8	15231748
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DST AP1B1 PI4KB CEP192 TIPRL RAB11FIP1 MAST2	2.13e-04	446	94	7	24255178
Pubmed	The N-terminal coiled-coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with Galphaq.	CYTH3 CYTH2	2.57e-04	9	94	2	17846866
Pubmed	Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.	DST PLEC	2.57e-04	9	94	2	12482924
Pubmed	Clint: a novel clathrin-binding ENTH-domain protein at the Golgi.	AP1B1 AP2B1	2.57e-04	9	94	2	12429846
Pubmed	Protein microarray analysis identifies human cellular prion protein interactors.	ZFYVE28 AGO1 ZKSCAN8	3.03e-04	48	94	3	18482256
Pubmed	Transcript map of the Ovum mutant (Om) locus: isolation by exon trapping of new candidate genes for the DDK syndrome.	AP1B1 AP2B1	3.21e-04	10	94	2	12383505
Pubmed	Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors.	CYTH3 CYTH2	3.21e-04	10	94	2	10828067
Pubmed	A human MAP kinase interactome.	DST AP2B1 CYTH2 GLUL AKAP13 PLEC MBD5	3.58e-04	486	94	7	20936779
Pubmed	The expression and function of netrin-4 in murine ocular tissues.	HSPG2 GLUL	3.91e-04	11	94	2	22281059
Pubmed	An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment.	MREG RBM24	3.91e-04	11	94	2	28729444
Pubmed	Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.	DST PLEC	3.91e-04	11	94	2	12802069
Pubmed	Expression of the mouse PR domain protein Prdm8 in the developing central nervous system.	PRDM8 GLUL	3.91e-04	11	94	2	19616129
Pubmed	The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.	DST PLEC	3.91e-04	11	94	2	10811835
Pubmed	Current insights into the formation and breakdown of hemidesmosomes.	DST PLEC	3.91e-04	11	94	2	16757171
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	XRN2 DST AP1B1 AP2B1 TUT7 SRP68 PLEC HP1BP3	3.99e-04	653	94	8	22586326
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	HSPG2 ZNF23 DST GSE1 SRP68 PLEC MAST2	4.09e-04	497	94	7	23414517
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	XRN2 DST ZGRF1 PLEC MAST2	4.46e-04	234	94	5	36243803
Cytoband	1q21.1	NBPF8 NBPF9 NBPF10 NBPF11 NBPF14	1.91e-07	62	94	5	1q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	NBPF19 NBPF12 PI4KB NBPF9 NBPF10 NBPF11 NBPF14 NBPF20	1.93e-06	404	94	8	chr1q21
Cytoband	Ensembl 112 genes in cytogenetic band chr1p11	NBPF8 NBPF26	8.49e-04	21	94	2	chr1p11
Cytoband	7p12.3	ABCA13 PKD1L1	9.33e-04	22	94	2	7p12.3
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF19 NBPF12 NBPF9 NBPF10 NBPF26 NBPF11 NBPF14 NBPF20	2.05e-17	23	60	9	662
GeneFamily	Non-canonical poly(A) polymerases	TUT4 TUT7	2.25e-04	7	60	2	1318
GeneFamily	EF-hand domain containing\|Plakins	DST PLEC	2.99e-04	8	60	2	939
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	MST1R ROR1 ROR2	3.15e-04	40	60	3	321
GeneFamily	Zinc fingers CCHC-type\|RNA binding motif containing	TUT4 TUT7	3.09e-03	25	60	2	74
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	SPHKAP AKAP13	4.15e-03	29	60	2	396
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	INPP4A RAB11FIP1	6.35e-03	36	60	2	823
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	TUT4 GSE1 CSNK1G2 CYTH2 TMEM175 TOGARAM2 NBPF10 IRF4 AKAP13 CEP192 NBPF11 RAB11FIP1 NBPF14 DUS1L STK25	7.69e-07	905	94	15	M40865
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	TUT4 CSNK1G2 CYTH2 TMEM175 TOGARAM2 NBPF10 AKAP13 NBPF11 NBPF14 DUS1L STK25	1.71e-05	634	94	11	M40866
Coexpression	GSE13547_WT_VS_ZFX_KO_BCELL_UP	DST CYTH3 CHD9 CREG2 PNPLA7 GLCCI1	2.73e-05	163	94	6	M2997
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	DST SPHKAP ROR1 CTNNA3 AKAP13 ADPRHL1 RBM24	1.92e-07	195	94	7	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MST1R SPHKAP ROR2 ADPRHL1 RBM24 DMPK	1.70e-06	171	94	6	82de2885c8ce4fb7776da6a0207b3355c0910121
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MST1R SPHKAP ROR2 ADPRHL1 RBM24 DMPK	1.70e-06	171	94	6	09e653973962fb884878089d281f0947f7a285f6
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SLC5A11 MREG ZNF23 NCAPG TM9SF1 IRF4	2.08e-06	177	94	6	d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SLC5A11 MREG ZNF23 NCAPG TM9SF1 IRF4	2.08e-06	177	94	6	65e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NCAPG ZGRF1 CHTF18 CEP192 MAST2 HP1BP3	3.13e-06	190	94	6	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	DST SPHKAP ROR1 CTNNA3 AKAP13 ADPRHL1	3.13e-06	190	94	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	DST SPHKAP ROR1 CTNNA3 AKAP13 ADPRHL1	3.23e-06	191	94	6	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF19 SPHKAP NBPF10 NBPF26 IL1RAP NBPF14	4.21e-06	200	94	6	47791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF19 SPHKAP NBPF10 NBPF26 IL1RAP NBPF14	4.21e-06	200	94	6	f75d95376a340d467c4392b872b2a2dbdd184556
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF19 SPHKAP NBPF10 NBPF26 IL1RAP NBPF14	4.21e-06	200	94	6	fae26560ba3b0b638b6bcf92f05330824b31d21b
ToppCell	Severe-B_intermediate-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 FAM13C TUT7 NBPF10 NBPF11	7.15e-06	126	94	5	42a0bdbe18ef85146cac4e86b2b27d0b3b20d8a2
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF12 TUT7 NBPF10 NBPF11	1.37e-05	144	94	5	984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell	10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-LMPP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ZFYVE28 GBP7 CREG2 CALHM3 ZNF114	2.01e-05	156	94	5	331b63bf4744ab494c3959436a8a0d8a1e4c0de4
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MREG NCAPG IRF4 SLC10A3 GASK1A	2.34e-05	161	94	5	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF12 TUT7 NBPF10 NBPF11	2.79e-05	167	94	5	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NBPF19 SPHKAP NBPF10 IL1RAP NBPF14	3.30e-05	173	94	5	8ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell	droplet-Lung-nan-18m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPG ZGRF1 CHTF18 BARX2 MAST2	3.30e-05	173	94	5	20a20429aa898097d5ec4880ed64846558b5890f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NBPF19 PRDM8 SPHKAP IL1RAP NBPF14	3.39e-05	174	94	5	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_B-plasmablast-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MREG HSPG2 NCAPG IRF4 GLCCI1	3.49e-05	175	94	5	89bf89466191da14896ed8928027f5b911436c22
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NBPF8 CHTF18 NBPF10 COLCA1 NBPF20	3.49e-05	175	94	5	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NBPF19 PRDM8 SPHKAP IL1RAP NBPF14	3.58e-05	176	94	5	40993c41c1017b53039a337174fc56632b278609
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZFYVE28 IRF4 CAGE1 CREG2 GLCCI1	3.68e-05	177	94	5	41cbb2c109eaa7be366fc0510cce64abc06837b4
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPHKAP ROR1 CTNNA3 ADPRHL1 RBM24	4.10e-05	181	94	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFRP4 SPHKAP ROR1 ROR2 GASK1A	4.32e-05	183	94	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRDM8 NCAPG ZGRF1 CHTF18 DOK2	4.43e-05	184	94	5	b998803180322a5ea2b567928dea531c26816c3c
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	DST ROR1 CTNNA3 AKAP13 ADPRHL1	4.43e-05	184	94	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPHKAP ROR1 CTNNA3 ADPRHL1 RBM24	4.43e-05	184	94	5	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPHKAP ROR1 CTNNA3 ADPRHL1 RBM24	4.54e-05	185	94	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CSNK1G2 NBPF26 FAM117B CEP192 MBD5	4.54e-05	185	94	5	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CSNK1G2 NBPF26 FAM117B CEP192 MBD5	4.54e-05	185	94	5	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FAM13C SPHKAP ROR1 CTNNA3 ADPRHL1	4.54e-05	185	94	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFRP4 NBPF26 FAM117B CEP192 GASK1A	4.66e-05	186	94	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	SFRP4 NBPF26 FAM117B CEP192 GASK1A	4.66e-05	186	94	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MREG HSPG2 CTNNA3 RAB11FIP1 GLCCI1	4.78e-05	187	94	5	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	COPD-Myeloid-cMonocyte\|COPD / Disease state, Lineage and Cell class	NBPF19 NBPF10 NBPF26 IL1RAP NBPF14	5.03e-05	189	94	5	d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	SPHKAP ROR1 CTNNA3 ADPRHL1 MAST2	5.03e-05	189	94	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	SPHKAP ROR1 CTNNA3 AKAP13 ADPRHL1	5.03e-05	189	94	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	ROR1 CTNNA3 AKAP13 RBM24 MAST2	5.03e-05	189	94	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	NBPF19 TUT7 NBPF26 FAM117B NBPF14	5.16e-05	190	94	5	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	NBPF19 TUT7 NBPF26 FAM117B NBPF14	5.16e-05	190	94	5	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	ROR1 CTNNA3 AKAP13 RBM24 MAST2	5.16e-05	190	94	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	SPHKAP ROR1 CTNNA3 AKAP13 ADPRHL1	5.16e-05	190	94	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	SPHKAP ROR1 CTNNA3 ADPRHL1 RBM24	5.29e-05	191	94	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFRP4 FAM13C ROR1 ROR2 GASK1A	5.29e-05	191	94	5	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	SPHKAP ROR1 CTNNA3 ADPRHL1 MAST2	5.42e-05	192	94	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MREG SFRP4 ROR1 IRF4 RAB11FIP1	5.56e-05	193	94	5	7426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCell	COPD-Myeloid-ncMonocyte\|COPD / Disease state, Lineage and Cell class	NBPF19 TUT7 NBPF26 FAM117B NBPF14	5.56e-05	193	94	5	936ca95995599356b794fba32bfd82d8de339365
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MREG SFRP4 ROR1 IRF4 RAB11FIP1	5.56e-05	193	94	5	a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SLFN12L DST GSE1 ROR1 ROR2	5.69e-05	194	94	5	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	SPHKAP ROR1 CTNNA3 ADPRHL1 RBM24	5.83e-05	195	94	5	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SLFN12L DST ROR1 ROR2 MBD5	5.83e-05	195	94	5	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	COVID-19-Heart-Mito_CM\|COVID-19 / Disease (COVID-19 only), tissue and cell type	VGLL2 SPHKAP CTNNA3 ADPRHL1 RBM24	6.12e-05	197	94	5	44e49943d62bfe622b40ad0460093d31540544df
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	SLFN12L TUT4 DST TMEM175 NBPF14	6.12e-05	197	94	5	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / Treatment groups by lineage, cell group, cell type	SLC5A11 WDR93 HSPG2 NCAPG AGO1	6.12e-05	197	94	5	038fd92750257d43d5e980fd06d77742b543f11a
ToppCell	medial-2-mesenchymal-Myofibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP4 COMP VGLL2 ROR2 GASK1A	6.42e-05	199	94	5	95aae608fa35a9c82b12c6f18937ce636750ca44
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP4 COMP ROR1 ROR2 GASK1A	6.42e-05	199	94	5	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	medial-mesenchymal-Myofibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP4 COMP VGLL2 ROR2 GASK1A	6.42e-05	199	94	5	e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCell	medial-mesenchymal-Myofibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SFRP4 COMP VGLL2 ROR2 GASK1A	6.42e-05	199	94	5	9ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	NBPF19 PRDM8 BARX2 IL1RAP NBPF14	6.58e-05	200	94	5	e0eccfdef3a1b4ffb47e7496764c7cf339618d39
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	SFRP4 DST SPHKAP LRP3 GASK1A	6.58e-05	200	94	5	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MREG MST1R BARX2 HP1BP3	1.03e-04	115	94	4	207d464c09caf9be361daa56c83cd7da5cf9ce47
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	GBP7 CLEC4A NBPF20 ZNF114	1.38e-04	124	94	4	80526f503e1477b9455d10f27f7e6b56caea3a66
Drug	Pesticides	NBPF8 NBPF12 NBPF9 NBPF10 NBPF11 IL1RAP NBPF14 NBPF20	1.72e-07	150	92	8	ctd:D010575
Disease	retinal vasculature measurement	HSPG2 XRN2 ROR2 CTNNA3 GLUL IRF4 BARX2 DENND2B GLCCI1	2.22e-05	517	87	9	EFO_0010554
Disease	epidermolysis bullosa simplex (is_implicated_in)	DST PLEC	1.79e-04	7	87	2	DOID:4644 (is_implicated_in)
Disease	frozen shoulder	SFRP4 AKAP13	1.79e-04	7	87	2	EFO_1000941
Disease	platelet measurement	SLFN12L GSE1 AP2B1 CAPZA2 CHD9 PLEC	3.45e-04	315	87	6	EFO_0005036
Disease	immature platelet measurement	GSE1 AP2B1 CAPZA2 PLEC	4.32e-04	119	87	4	EFO_0803541
Disease	Ck-beta-8-1 measurement	SLFN12L AP2B1	5.56e-04	12	87	2	EFO_0008085
Disease	red blood cell density measurement	PRDM8 XRN2 DST TM9SF1 CAPZA2 AKAP13 PLEC MAST2 DENND2B	1.15e-03	880	87	9	EFO_0007978
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 COMP	1.42e-03	19	87	2	DOID:2256 (is_implicated_in)
Disease	peripheral neuropathy, response to docetaxel trihydrate	SPHKAP CTNNA3	1.42e-03	19	87	2	EFO_0003100, GO_1902519
Disease	Disproportionate short stature	HSPG2 COMP ROR2	1.55e-03	77	87	3	C0878659
Disease	platelet component distribution width	GSE1 AP2B1 CAPZA2 AKAP13 DOK2 ADPRHL1 PLEC ZNF496	1.75e-03	755	87	8	EFO_0007984
Disease	obsolete_red blood cell distribution width	SLFN12L XRN2 FAM117A AP2B1 CSNK1G2 TUT7 AKAP13 TIPRL DENND2B BTRC HP1BP3	2.00e-03	1347	87	11	EFO_0005192
Disease	health study participation	SLC5A11 MST1R NCAPG CTNNA3	2.68e-03	195	87	4	EFO_0010130

Protein segments in the cluster

Peptide	Gene	Start	Entry
RLEPNVEELCRFPEL	CHTF18	816	Q8WVB6
CVKEETPRAAREPEE	AMER2	236	Q8N7J2
PRKRSQAELCADPKE	CCL21	66	O00585
SPCEERLNPADIKRA	CAGE1	596	Q8TC20
FVKDCEDPNPLIRAL	AP2B1	91	P63010
PCKEDELVRDSPARK	CALHM3	156	Q86XJ0
PDEKLRCPERQCRKD	COMP	276	P49747
FKREPPEGCEKVRVF	FAM117A	336	Q9C073
ERVFCPEKAEEGPRK	GSE1	626	Q14687
EREDCNNGEPPRKII	BTRC	56	Q9Y297
PDKCPRRVNREVVEY	AGO1	61	Q9UL18
PVRDTQERADFCPFK	AKAP13	721	Q12802
RKENLYCEVCPEDRP	DUS1L	61	Q6P1R4
RKFRDQDLPCADLNP	ABCA13	4286	Q86UQ4
KREPPEGCERVKVFE	GLCCI1	416	Q86VQ1
ADFEAINRCNRPLPK	ACSM4	36	P0C7M7
FVKDCEDPNPLIRAL	AP1B1	91	Q10567
EERLKAIPQFCFPDA	DENND2B	736	P78524
APRVDCAFLDQPREL	ATP4B	196	P51164
EFCRKNIVDPEDPRC	CREG2	201	Q8IUH2
DVLPLAFTRLCEPKE	HP1BP3	261	Q5SSJ5
DRAAAERACKDPNPI	RBM24	61	Q9BX46
EDRTDEANCPTKRPE	HSPG2	351	P98160
QFKEVLPEDCLPRSR	INPP4A	836	Q96PE3
PQDRAPRDFCVKFPE	ZFYVE28	76	Q9HCC9
PRDFCVKFPEEIRHD	ZFYVE28	81	Q9HCC9
LELQEGPEKPRRCEA	DOK2	41	O60496
CFGEEFPDPQRQRKL	IRF4	386	Q15306
REANDVDEDRPKIFP	GPR179	1056	Q6PRD1
QVFEDEPARIKCPLF	IL1RAP	36	Q9NPH3
LPRDEKLKDLCNDFP	DST	3351	Q03001
KRATPIEVLCENFPE	CSNK1G2	271	P78368
LNDCFKKVPRDEDDP	FOXI2	156	Q6ZQN5
PPTLIEERRDFCIKV	SLC10A3	156	P09131
PECRPVDKDRKVCRE	LRP3	691	O75074
LIRAKSCPRPDEVED	GBP7	151	Q8N8V2
VPEEARDFIQRLLCP	DMPK	306	Q09013
EERLKKPPRLQESCD	PNPLA7	321	Q6ZV29
ERFTDDPCFLPKREA	CTNNA3	106	Q9UI47
PSDPCVEERLREKCQ	GASK1A	446	Q9UFP1
DPALCFLERVGKPDE	CHD9	1701	Q3L8U1
RVCRLPSKEELVDPN	CHD9	1896	Q3L8U1
RKLDFSRPEPCFEKE	COLCA1	101	Q6ZS62
FKREPPEGCERVKVF	FAM117B	466	Q6P1L5
EELCEAQEPKARDVP	BARX2	241	Q9UMQ3
IREVDDPRKPNCFEL	CYTH2	311	Q99418
IREVEDPRKPNCFEL	CYTH3	316	O43739
CYVEIVEKLPERRPD	ADPRHL1	86	Q8NDY3
ARPARLLECLEFDPE	MAST2	421	Q6P0Q8
PRNCPGDKILEENFR	MBD5	1251	Q9P267
PKDPEACEERILKIF	CEP192	1716	Q8TEP8
ELSCPEKPLFERNSR	PKD1L1	1831	Q8TDX9
RDPFRKDPNKLVLCE	GLUL	86	P15104
DTDEIPAKRPRLDCF	SENP2	41	Q9HC62
RQEEELPRFPCKKQD	RAB11FIP1	701	Q6WKZ4
INFDLEPECPDAELR	SPHKAP	1611	Q2M3C7
REACPPLKEEDQKEI	TOGARAM2	331	Q6ZUX3
CPRLSRELLDEKEPE	NBPF8	656	Q3BBV2
CPRLSRELLDEKEPE	NBPF9	691	P0DPF3
CPRLSRELLDEKEPE	NBPF10	691	Q6P3W6
CPRLSRELLDEKEPE	NBPF10	1911	Q6P3W6
CPRLSRELLDEKEPE	NBPF10	3131	Q6P3W6
CPRLSRELLAEKEPE	NBPF11	691	Q86T75
CPRLSRELLAEKEPE	NBPF12	1131	Q5TAG4
CPRLSRELLAEKEPE	NBPF12	1206	Q5TAG4
CPRLSRELLDEKEPE	NBPF14	351	Q5TI25
CPRLSRELLDEKEPE	NBPF19	1396	A0A087WUL8
CPRLSRELLDEKEPE	NBPF19	2616	A0A087WUL8
AEKEPEVLQDPLDRC	NBPF19	3601	A0A087WUL8
CPRLSRELLDEKEPE	NBPF20	76	P0DPF2
CPRLSRELLDEKEPE	NBPF20	1296	P0DPF2
CPRLSRELLDEKEPE	NBPF20	2516	P0DPF2
CPRLSRELLDEKEPE	NBPF20	3736	P0DPF2
CPRLSRELLDEKEPE	NBPF20	4956	P0DPF2
CPRLSRELLDEKEPE	NBPF26	651	B4DH59
CECLEERALPEKEPL	MREG	16	Q8N565
FVERPLPASKEDLVC	PRDM8	336	Q9NQV8
RILFPDQVACADPEI	SLC5A11	331	Q8WWX8
PKPRELCRDECEVLE	ROR2	246	Q01974
TCLKERREQLPPQED	FAM13C	396	Q8NE31
EIRCLDDPPAQIREE	PI4KB	86	Q9UBF8
FVEACLNKDPRFRPT	STK25	246	O00506
NKPLVERFETFCLDP	SRP68	551	Q9UHB9
ELNDSPVPLELERCK	STXBP5L	731	Q9Y2K9
LRKEATDPRPCEVEN	CAPZA2	101	P47755
PSDPNERCVVLNFRK	CLEC4A	196	Q9UMR7
LSRLQDPKDDECPVV	NCAPG	166	Q9BPX3
VPKPRDLCRDECEIL	ROR1	241	Q01973
CEDNVPDPKDVKERF	TMEM175	281	Q9BSA9
EKERPPEAEYINSRC	VGLL2	71	Q8N8G2
LRPEFPAKRACVDVQ	SLFN12L	176	Q6IEE8
EAVCEKLIFPERIDP	TIPRL	246	O75663
VQERPLDVDCKRLSP	SFRP4	161	Q6FHJ7
LPPEEIKERFDSNCI	XRN2	146	Q9H0D6
LPLDKEPARECAQRI	PLEC	1146	Q15149
RKREELQVPEFQACP	ZNF496	311	Q96IT1
AFPQALPLEKRCERF	WDR93	636	Q6P2C0
EPASLLPIARFECEK	ZGRF1	1816	Q86YA3
RPFKCEELVEPFRCD	ZNF23	166	P17027
KDCPEDFKRIQLEPL	TUT7	976	Q5VYS8
NDCPEDFRKIDLKPL	TUT4	926	Q5TAX3
LRPVPRKDFVEEFEC	MST1R	626	Q04912
RNPEDDGCLLKQEPR	nan	76	Q8N7P7
LDPSQKDLCRDNRPE	ZKSCAN8	236	Q15776
FDAPCRTKNIAREIP	TM9SF1	441	O15321
DILPKRTFPEANRVC	ZNF114	61	Q8NC26