Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	dynein light intermediate chain binding	BICD2 CCDC88B DNAH11	1.11e-04	28	67	3	GO:0051959
GeneOntologyMolecularFunction	SMAD binding	TCF12 SKI SKIL USP15	2.00e-04	86	67	4	GO:0046332
GeneOntologyMolecularFunction	spectrin binding	SPTBN4 GBP1 GBP2	2.01e-04	34	67	3	GO:0030507
GeneOntologyMolecularFunction	cytoskeletal protein binding	TAOK2 BICD2 SPTBN4 CENPF SYNM HAP1 SPTBN2 GAS8 GBP1 GBP2 CCDC88B MTUS2	2.63e-04	1099	67	12	GO:0008092
GeneOntologyMolecularFunction	protein dimerization activity	TCF4 ERBB2 TCF12 PDCD6IP GBP4 CENPF GBP1 GBP2 DGKH CLPX KYNU MTUS2	6.04e-04	1205	67	12	GO:0046983
GeneOntologyMolecularFunction	GDP phosphatase activity	GBP1 GBP2	7.16e-04	12	67	2	GO:0004382
GeneOntologyMolecularFunction	Hsp90 protein binding	ERBB2 GBP1 GBP2	8.36e-04	55	67	3	GO:0051879
GeneOntologyBiologicalProcess	cytolysis in another organism	GBP4 GBP1 GBP2	2.71e-06	9	67	3	GO:0051715
GeneOntologyBiologicalProcess	positive regulation of pyroptotic inflammatory response	GBP4 GBP1 GBP2	2.71e-06	9	67	3	GO:0140639
GeneOntologyBiologicalProcess	microtubule-based process	BICD2 ERBB2 TEKT2 PDCD6IP HAP1 ODAD1 PDE4DIP GAS8 NINL CCDC120 BSN CCDC88B CEP128 DNAH11	6.13e-06	1058	67	14	GO:0007017
GeneOntologyBiologicalProcess	cytolysis	GBP4 GBP1 GBP2	7.06e-06	12	67	3	GO:0019835
GeneOntologyBiologicalProcess	defense response to protozoan	GBP4 GBP1 GBP2 CCDC88B	7.68e-06	39	67	4	GO:0042832
GeneOntologyBiologicalProcess	response to protozoan	GBP4 GBP1 GBP2 CCDC88B	1.04e-05	42	67	4	GO:0001562
GeneOntologyBiologicalProcess	microtubule anchoring at microtubule organizing center	BICD2 NINL CCDC120	1.16e-05	14	67	3	GO:0072393
GeneOntologyBiologicalProcess	adhesion of symbiont to host	GBP4 GBP1 GBP2	3.59e-05	20	67	3	GO:0044406
GeneOntologyBiologicalProcess	positive regulation of AIM2 inflammasome complex assembly	GBP1 GBP2	6.21e-05	4	67	2	GO:0140973
GeneOntologyBiologicalProcess	microtubule anchoring	BICD2 NINL CCDC120	7.16e-05	25	67	3	GO:0034453
GeneOntologyBiologicalProcess	regulation of AIM2 inflammasome complex assembly	GBP1 GBP2	1.55e-04	6	67	2	GO:0140971
GeneOntologyBiologicalProcess	microtubule-based movement	BICD2 TEKT2 HAP1 ODAD1 GAS8 BSN CEP128 DNAH11	1.91e-04	493	67	8	GO:0007018
GeneOntologyBiologicalProcess	AIM2 inflammasome complex assembly	GBP1 GBP2	2.87e-04	8	67	2	GO:0140970
GeneOntologyBiologicalProcess	cellular response to interferon-beta	GBP4 GBP1 GBP2	3.20e-04	41	67	3	GO:0035458
GeneOntologyBiologicalProcess	pyroptotic inflammatory response	GBP4 GBP1 GBP2	3.43e-04	42	67	3	GO:0070269
GeneOntologyBiologicalProcess	regulation of microtubule-based process	BICD2 ERBB2 PDCD6IP HAP1 PDE4DIP DNAH11	3.77e-04	293	67	6	GO:0032886
GeneOntologyBiologicalProcess	positive regulation of inflammatory response	TRADD GBP4 GBP1 GBP2 TNFRSF1A	4.11e-04	193	67	5	GO:0050729
GeneOntologyBiologicalProcess	response to interferon-beta	GBP4 GBP1 GBP2	5.10e-04	48	67	3	GO:0035456
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	BICD2 TEKT2 PDCD6IP ODAD1 PDE4DIP GAS8 NINL CCDC120 CCDC88B	5.12e-04	720	67	9	GO:0000226
GeneOntologyCellularComponent	microtubule organizing center	BICD2 WHRN CDC42BPG TEKT2 RPGRIP1L PDCD6IP CENPF HAP1 CEP95 PDE4DIP GAS8 NINL CCDC120 SKI CCDC88B CEP128 MTUS2	4.01e-09	919	68	17	GO:0005815
GeneOntologyCellularComponent	host cell part	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0033643
GeneOntologyCellularComponent	host intracellular part	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0033646
GeneOntologyCellularComponent	host cell cytoplasm part	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0033655
GeneOntologyCellularComponent	symbiont-containing vacuole	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0020003
GeneOntologyCellularComponent	symbiont-containing vacuole membrane	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0020005
GeneOntologyCellularComponent	host intracellular region	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0043656
GeneOntologyCellularComponent	host cell cytoplasm	GBP4 GBP1 GBP2	6.54e-07	6	68	3	GO:0030430
GeneOntologyCellularComponent	centrosome	BICD2 CDC42BPG RPGRIP1L PDCD6IP CENPF HAP1 CEP95 PDE4DIP NINL SKI CCDC88B CEP128 MTUS2	1.00e-06	770	68	13	GO:0005813
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	SPTBN4 TLK2 WHRN TEKT2 RPGRIP1L SYNM PDE4DIP GAS8 NINL SYNC EIF3A MTUS2 DNAH11	5.51e-06	899	68	13	GO:0099513
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	TEKT2 RPGRIP1L CENPF HAP1 ODAD1 GAS8 BSN DNAH11	8.59e-06	317	68	8	GO:0032838
GeneOntologyCellularComponent	host cellular component	GBP4 GBP1 GBP2	1.46e-05	15	68	3	GO:0018995
GeneOntologyCellularComponent	cytoplasmic region	TEKT2 RPGRIP1L CENPF HAP1 ODAD1 GAS8 BSN DNAH11	2.15e-05	360	68	8	GO:0099568
GeneOntologyCellularComponent	axoneme	TEKT2 RPGRIP1L CENPF ODAD1 GAS8 DNAH11	5.76e-05	207	68	6	GO:0005930
GeneOntologyCellularComponent	ciliary plasm	TEKT2 RPGRIP1L CENPF ODAD1 GAS8 DNAH11	5.91e-05	208	68	6	GO:0097014
GeneOntologyCellularComponent	tumor necrosis factor receptor superfamily complex	TRADD TNFRSF1A	6.23e-05	4	68	2	GO:0002947
GeneOntologyCellularComponent	supramolecular fiber	SPTBN4 TLK2 WHRN TEKT2 RPGRIP1L SYNM PDE4DIP GAS8 NINL SYNC EIF3A MTUS2 DNAH11	9.43e-05	1179	68	13	GO:0099512
GeneOntologyCellularComponent	actin cytoskeleton	TAOK2 SPTBN4 WHRN PDCD6IP HAP1 SPTBN2 GBP1 GBP2 DGKH	9.97e-05	576	68	9	GO:0015629
GeneOntologyCellularComponent	supramolecular polymer	SPTBN4 TLK2 WHRN TEKT2 RPGRIP1L SYNM PDE4DIP GAS8 NINL SYNC EIF3A MTUS2 DNAH11	1.01e-04	1187	68	13	GO:0099081
GeneOntologyCellularComponent	symbiont cell surface	GBP1 GBP2	2.88e-04	8	68	2	GO:0106139
GeneOntologyCellularComponent	microtubule	TEKT2 RPGRIP1L PDE4DIP GAS8 NINL EIF3A MTUS2 DNAH11	3.27e-04	533	68	8	GO:0005874
GeneOntologyCellularComponent	other organism part	GBP1 GBP2	3.70e-04	9	68	2	GO:0044217
GeneOntologyCellularComponent	spectrin	SPTBN4 SPTBN2	3.70e-04	9	68	2	GO:0008091
GeneOntologyCellularComponent	ciliary basal body	WHRN RPGRIP1L CENPF GAS8 CEP128	4.34e-04	195	68	5	GO:0036064
GeneOntologyCellularComponent	centriolar subdistal appendage	CCDC120 CEP128	4.61e-04	10	68	2	GO:0120103
GeneOntologyCellularComponent	cilium	WHRN TEKT2 RPGRIP1L CENPF PROM2 ODAD1 GAS8 CCDC120 CEP128 DNAH11	6.17e-04	898	68	10	GO:0005929
GeneOntologyCellularComponent	cell-cell junction	SPTBN4 USP53 DCHS2 RPGRIP1L PDCD6IP SYNM SPTBN2 AMOTL1	6.47e-04	591	68	8	GO:0005911
GeneOntologyCellularComponent	cortical cytoskeleton	SPTBN4 SPTBN2 PDE4DIP BSN	8.31e-04	129	68	4	GO:0030863
GeneOntologyCellularComponent	perinuclear region of cytoplasm	TLK2 WHRN ERBB2 GBP4 CENPF HAP1 SPTBN2 GBP1 GBP2 SYNC	8.35e-04	934	68	10	GO:0048471
GeneOntologyCellularComponent	bicellular tight junction	USP53 RPGRIP1L PDCD6IP AMOTL1	8.80e-04	131	68	4	GO:0005923
GeneOntologyCellularComponent	cytoplasmic microtubule	TEKT2 RPGRIP1L PDE4DIP MTUS2	9.31e-04	133	68	4	GO:0005881
GeneOntologyCellularComponent	tight junction	USP53 RPGRIP1L PDCD6IP AMOTL1	1.10e-03	139	68	4	GO:0070160
GeneOntologyCellularComponent	apical junction complex	USP53 RPGRIP1L PDCD6IP AMOTL1	1.76e-03	158	68	4	GO:0043296
GeneOntologyCellularComponent	endosome	ERBB2 PDCD6IP HAP1 SPTBN2 TBCK CCDC120 DGKH SCAMP3 ANKRD50 EPN1	4.29e-03	1167	68	10	GO:0005768
GeneOntologyCellularComponent	postsynapse	TAOK2 WHRN ERBB2 DRP2 HAP1 SPTBN2 EIF3A BSN EPN1	5.54e-03	1018	68	9	GO:0098794
MousePheno	abnormal motile cilium physiology	TEKT2 PDCD6IP GAS8 DNAH11	6.17e-05	51	59	4	MP:0013209
MousePheno	abnormal cilium physiology	TEKT2 PDCD6IP GAS8 DNAH11	7.18e-05	53	59	4	MP:0013208
MousePheno	abnormal tracheal ciliated epithelium morphology	TEKT2 PDCD6IP GAS8	7.74e-05	20	59	3	MP:0002285
Domain	GOLGA6L	GOLGA6L10 GOLGA6L19 GOLGA6L4	1.04e-06	6	71	3	IPR026737
Domain	GBP_C	GBP4 GBP1 GBP2	6.20e-06	10	71	3	PF02841
Domain	G_GB1_RHD3_dom	GBP4 GBP1 GBP2	8.50e-06	11	71	3	IPR030386
Domain	Guanylate-bd_C	GBP4 GBP1 GBP2	8.50e-06	11	71	3	IPR003191
Domain	GBP	GBP4 GBP1 GBP2	8.50e-06	11	71	3	PF02263
Domain	Guanylate-bd_N	GBP4 GBP1 GBP2	8.50e-06	11	71	3	IPR015894
Domain	G_GB1_RHD3	GBP4 GBP1 GBP2	8.50e-06	11	71	3	PS51715
Domain	GOLGA2L5	GOLGA6L10 GOLGA6L19 GOLGA6L4	4.12e-05	18	71	3	PF15070
Domain	Golgin_A	GOLGA6L10 GOLGA6L19 GOLGA6L4	4.12e-05	18	71	3	IPR024858
Domain	c-SKI_SMAD4-bd_dom	SKI SKIL	8.51e-05	4	71	2	IPR014890
Domain	Tscrpt_reg_SKI_SnoN	SKI SKIL	8.51e-05	4	71	2	IPR023216
Domain	c-SKI_SMAD_bind	SKI SKIL	8.51e-05	4	71	2	PF08782
Domain	Spectrin_bsu	SPTBN4 SPTBN2	8.51e-05	4	71	2	IPR016343
Domain	c-SKI_SMAD_bind	SKI SKIL	8.51e-05	4	71	2	SM01046
Domain	Spectrin	SPTBN4 DRP2 SPTBN2	8.83e-05	23	71	3	PF00435
Domain	Spectrin_repeat	SPTBN4 DRP2 SPTBN2	1.79e-04	29	71	3	IPR002017
Domain	Spectrin/alpha-actinin	SPTBN4 DRP2 SPTBN2	2.41e-04	32	71	3	IPR018159
Domain	SPEC	SPTBN4 DRP2 SPTBN2	2.41e-04	32	71	3	SM00150
Domain	Ski_Sno	SKI SKIL	2.96e-04	7	71	2	PF02437
Domain	-	SKI SKIL	2.96e-04	7	71	2	3.10.260.20
Domain	Transform_Ski	SKI SKIL	2.96e-04	7	71	2	IPR003380
Domain	PH_dom-spectrin-type	SPTBN4 SPTBN2	5.04e-04	9	71	2	IPR001605
Domain	DNA-bd_dom_put	SKI SKIL	7.66e-04	11	71	2	IPR009061
Domain	-	SKI SKIL	9.18e-04	12	71	2	3.10.390.10
Domain	SAND_dom-like	SKI SKIL	9.18e-04	12	71	2	IPR010919
Domain	-	SPTBN4 CEP95 SPTBN2	2.50e-03	71	71	3	1.10.418.10
Domain	CH-domain	SPTBN4 CEP95 SPTBN2	2.92e-03	75	71	3	IPR001715
Domain	RHOD	TBCK DUSP9	3.13e-03	22	71	2	SM00450
Domain	Actinin_actin-bd_CS	SPTBN4 SPTBN2	3.42e-03	23	71	2	IPR001589
Domain	RHODANESE_3	TBCK DUSP9	3.42e-03	23	71	2	PS50206
Domain	ACTININ_2	SPTBN4 SPTBN2	3.42e-03	23	71	2	PS00020
Domain	ACTININ_1	SPTBN4 SPTBN2	3.42e-03	23	71	2	PS00019
Domain	Rhodanese-like_dom	TBCK DUSP9	3.73e-03	24	71	2	IPR001763
Domain	Rhodanese	TBCK DUSP9	3.73e-03	24	71	2	PF00581
Domain	UIM	HUWE1 EPN1	3.73e-03	24	71	2	PS50330
Domain	-	TBCK DUSP9	3.73e-03	24	71	2	3.40.250.10
Domain	UIM_dom	HUWE1 EPN1	4.04e-03	25	71	2	IPR003903
Domain	Kinase-like_dom	TAOK2 TLK2 CDC42BPG ERBB2 PDCD6IP BMP2K TBCK	4.46e-03	542	71	7	IPR011009
Domain	DEATH	TRADD TNFRSF1A	4.70e-03	27	71	2	SM00005
Domain	Death	TRADD TNFRSF1A	6.97e-03	33	71	2	PF00531
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	TCF4 TCF12 SKI SKIL USP15	1.71e-04	161	46	5	M27871
Pathway	KEGG_MEDICUS_REFERENCE_TNF_RIPK1_3_SIGNALING_PATHWAY	TRADD TNFRSF1A	2.16e-04	7	46	2	M47944
Pathway	WP_CILIOPATHIES	RPGRIP1L CENPF ODAD1 GAS8 DNAH11	3.19e-04	184	46	5	M39880
Pathway	BIOCARTA_SODD_PATHWAY	TRADD TNFRSF1A	4.61e-04	10	46	2	M2699
Pathway	KEGG_MEDICUS_REFERENCE_EXTRINSIC_APOPTOTIC_PATHWAY	TRADD TNFRSF1A	4.61e-04	10	46	2	M47447
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN4 SPTBN2	4.61e-04	10	46	2	MM15112
Pathway	BIOCARTA_SODD_PATHWAY	TRADD TNFRSF1A	4.61e-04	10	46	2	MM1497
Pubmed	Unique features of different members of the human guanylate-binding protein family.	GBP4 GBP1 GBP2	8.13e-08	5	71	3	17266443
Pubmed	Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.	GBP4 GBP1 GBP2	8.13e-08	5	71	3	21151871
Pubmed	TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation.	TRADD HUWE1 TNFRSF1A	2.84e-07	7	71	3	22561347
Pubmed	In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.	GBP4 GBP1 GBP2	4.53e-07	8	71	3	16689661
Pubmed	Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases.	GBP4 GBP1 GBP2	6.79e-07	9	71	3	24739961
Pubmed	Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.	GBP4 GBP1 GBP2	1.33e-06	11	71	3	24715728
Pubmed	Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.	GBP4 GBP1 GBP2	1.33e-06	11	71	3	18025219
Pubmed	Pathogen-selective killing by guanylate-binding proteins as a molecular mechanism leading to inflammasome signaling.	GBP4 GBP1 GBP2	1.77e-06	12	71	3	35906252
Pubmed	Intersectin (ITSN) family of scaffolds function as molecular hubs in protein interaction networks.	PDCD6IP AMOTL1 PDE4DIP SYNC MTUS2	3.33e-06	111	71	5	22558309
Pubmed	Dimerization and its role in GMP formation by human guanylate binding proteins.	GBP1 GBP2	4.11e-06	2	71	2	20923658
Pubmed	Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD.	TRADD TNFRSF1A	4.11e-06	2	71	2	8621670
Pubmed	Ski/SnoN expression in the sequence metaplasia-dysplasia-adenocarcinoma of Barrett's esophagus.	SKI SKIL	4.11e-06	2	71	2	18261624
Pubmed	Complex formation between proteins encoded by the ski gene family.	SKI SKIL	4.11e-06	2	71	2	8514802
Pubmed	Isolation of human cDNA clones of ski and the ski-related gene, sno.	SKI SKIL	4.11e-06	2	71	2	2762147
Pubmed	Proto-oncogene Sno expression, alternative isoforms and immediate early serum response.	SKI SKIL	4.11e-06	2	71	2	9207045
Pubmed	Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain.	TCF4 TCF12	4.11e-06	2	71	2	7984047
Pubmed	Hepatitis C virus core protein potentiates c-Jun N-terminal kinase activation through a signaling complex involving TRADD and TRAF2.	TRADD TNFRSF1A	4.11e-06	2	71	2	11226577
Pubmed	The human papillomavirus 16 E6 protein binds to tumor necrosis factor (TNF) R1 and protects cells from TNF-induced apoptosis.	TRADD TNFRSF1A	4.11e-06	2	71	2	11934887
Pubmed	Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents.	SKI SKIL	4.11e-06	2	71	2	9927733
Pubmed	Differential expression of interferon inducible protein: Guanylate binding protein (GBP1 & GBP2) in severe dengue.	GBP1 GBP2	4.11e-06	2	71	2	36460216
Pubmed	The role of E-proteins in B- and T-lymphocyte development.	TCF4 TCF12	4.11e-06	2	71	2	9618760
Pubmed	The chromosome 16q region associated with ankylosing spondylitis includes the candidate gene tumour necrosis factor receptor type 1-associated death domain (TRADD).	TRADD TNFRSF1A	4.11e-06	2	71	2	19854717
Pubmed	Life and death of human vascular endothelial cells by stimulation with free fatty acids through death receptors.	TRADD TNFRSF1A	4.11e-06	2	71	2	25230327
Pubmed	Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration.	SKI SKIL	4.11e-06	2	71	2	12023281
Pubmed	Autophagy restricts Chlamydia trachomatis growth in human macrophages via IFNG-inducible guanylate binding proteins.	GBP1 GBP2	4.11e-06	2	71	2	23086406
Pubmed	The Concerted Action of E2-2 and HEB Is Critical for Early Lymphoid Specification.	TCF4 TCF12	4.11e-06	2	71	2	30936870
Pubmed	Commensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.	GBP1 GBP2	4.11e-06	2	71	2	20483731
Pubmed	SKI controls MDS-associated chronic TGF-β signaling, aberrant splicing, and stem cell fitness.	SKI SKIL	4.11e-06	2	71	2	30249787
Pubmed	TGF-beta repressors SnoN and Ski are implicated in human colorectal carcinogenesis.	SKI SKIL	4.11e-06	2	71	2	19096149
Pubmed	Clinical significance of the expression of c-Ski and SnoN, possible mediators in TGF-beta resistance, in primary cutaneous melanoma.	SKI SKIL	4.11e-06	2	71	2	18782659
Pubmed	SnoI, a novel alternatively spliced isoform of the ski protooncogene homolog, sno.	SKI SKIL	4.11e-06	2	71	2	8233802
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TAOK2 SPTBN4 WHRN SPTBN2 CARNS1	7.22e-06	130	71	5	12421765
Pubmed	A family of IFN-γ-inducible 65-kD GTPases protects against bacterial infection.	GBP4 GBP1 GBP2	7.72e-06	19	71	3	21551061
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	TLK2 WHRN PDE4DIP EIF3A BSN DNAH11	8.44e-06	233	71	6	37704626
Pubmed	An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.	GBP4 GBP1 GBP2	1.06e-05	21	71	3	19158679
Pubmed	Activated T cells induce macrophages to produce NO and control Leishmania major in the absence of tumor necrosis factor receptor p55.	CD40LG TNFRSF1A	1.23e-05	3	71	2	10678956
Pubmed	Increased expression of c-Ski as a co-repressor in transforming growth factor-beta signaling correlates with progression of esophageal squamous cell carcinoma.	SKI SKIL	1.23e-05	3	71	2	14712482
Pubmed	Death domain complex of the TNFR-1, TRADD, and RIP1 proteins for death-inducing signaling.	TRADD TNFRSF1A	1.23e-05	3	71	2	24361886
Pubmed	Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa.	GBP1 GBP2	1.23e-05	3	71	2	30062052
Pubmed	A death-domain-containing receptor that mediates apoptosis.	TRADD TNFRSF1A	1.23e-05	3	71	2	8934525
Pubmed	The helix-loop-helix gene E2A is required for B cell formation.	TCF4 TCF12	1.23e-05	3	71	2	8001124
Pubmed	Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.	TCF4 TCF12	1.23e-05	3	71	2	30593567
Pubmed	Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages.	GBP1 GBP2	1.23e-05	3	71	2	26416908
Pubmed	Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1.	TRADD TNFRSF1A	1.23e-05	3	71	2	15247912
Pubmed	Are Ski and SnoN Involved in the Tumorigenesis of Oral Squamous Cell Carcinoma Through Smad4?	SKI SKIL	1.23e-05	3	71	2	29734252
Pubmed	Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7.	GBP1 GBP2	1.23e-05	3	71	2	32354743
Pubmed	GTPase properties of the interferon-induced human guanylate-binding protein 2.	GBP1 GBP2	1.23e-05	3	71	2	8706832
Pubmed	Guanylate binding proteins contained in the murine chromosome 3 are important to control mycobacterial infection.	GBP1 GBP2	1.23e-05	3	71	2	32620042
Pubmed	[Guanylate-binding protein 2 regulates the maturation of mouse dendritic cells induced by β-glucan].	GBP1 GBP2	1.23e-05	3	71	2	29089068
Pubmed	Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development.	TCF4 TCF12	1.23e-05	3	71	2	18854153
Pubmed	TNFα triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNFα responses of the parental cells.	TRADD TNFRSF1A	1.23e-05	3	71	2	26475675
Pubmed	Murine guanylate binding protein 2 (mGBP2) controls Toxoplasma gondii replication.	GBP1 GBP2	1.23e-05	3	71	2	23248289
Pubmed	Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP.	GBP1 GBP2	1.23e-05	3	71	2	1715024
Pubmed	GBP1 Facilitates Indoleamine 2,3-Dioxygenase Extracellular Secretion to Promote the Malignant Progression of Lung Cancer.	GBP1 GBP2	1.23e-05	3	71	2	33552086
Pubmed	Dysbindin, syncoilin, and beta-synemin mRNA levels in dystrophic muscles.	SYNM SYNC	1.23e-05	3	71	2	20199207
Pubmed	Two families of GTPases dominate the complex cellular response to IFN-gamma.	GBP1 GBP2	1.23e-05	3	71	2	9862701
Pubmed	The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation.	GBP1 GBP2	1.23e-05	3	71	2	11726669
Pubmed	Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses.	TRADD TNFRSF1A	1.23e-05	3	71	2	18641654
Pubmed	Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L.	CD40LG TNFRSF1A	1.23e-05	3	71	2	21410936
Pubmed	GBP2 inhibits pathological angiogenesis in the retina via the AKT/mTOR/VEGFA axis.	GBP1 GBP2	1.23e-05	3	71	2	38636926
Pubmed	ALF1, a basic helix-loop-helix transcription factor, maps to mouse chromosome 9.	TCF4 TCF12	1.23e-05	3	71	2	8833258
Pubmed	EMAP-II facilitates TNF-R1 apoptotic signalling in endothelial cells and induces TRADD mobilization.	TRADD TNFRSF1A	1.23e-05	3	71	2	17051333
Pubmed	E2-2 regulates the expansion of pro-B cells and follicular versus marginal zone decisions.	TCF4 TCF12	1.23e-05	3	71	2	17082585
Pubmed	Domain motions, dimerization, and membrane interactions of the murine guanylate binding protein 2.	GBP1 GBP2	1.23e-05	3	71	2	36639389
Pubmed	The ski/sno protooncogene family in hematopoietic development.	SKI SKIL	1.23e-05	3	71	2	7662963
Pubmed	The interferon-induced GTPase, mGBP-2, confers resistance to paclitaxel-induced cytotoxicity without inhibiting multinucleation.	GBP1 GBP2	1.23e-05	3	71	2	16914101
Pubmed	Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry.	BICD2 CENPF	1.23e-05	3	71	2	23097494
Pubmed	Murine helix-loop-helix transcriptional activator proteins binding to the E-box motif of the Akv murine leukemia virus enhancer identified by cDNA cloning.	TCF4 TCF12	1.23e-05	3	71	2	1321336
Pubmed	A role for E2-2 at the DN3 stage of early thymopoiesis.	TCF4 TCF12	1.23e-05	3	71	2	18384878
Pubmed	Alix and ALG-2 are involved in tumor necrosis factor receptor 1-induced cell death.	PDCD6IP TNFRSF1A	1.23e-05	3	71	2	18936101
Pubmed	The GTPase activity of murine guanylate-binding protein 2 (mGBP2) controls the intracellular localization and recruitment to the parasitophorous vacuole of Toxoplasma gondii.	GBP1 GBP2	1.23e-05	3	71	2	22730319
Pubmed	ME1 and GE1: basic helix-loop-helix transcription factors expressed at high levels in the developing nervous system and in morphogenetically active regions.	TCF4 TCF12	1.23e-05	3	71	2	8261111
Pubmed	CD40 ligand is not essential for the development of cell-mediated immunity and resistance to Mycobacterium tuberculosis.	CD40LG TNFRSF1A	1.23e-05	3	71	2	9498737
Pubmed	Inhibition of VSV and EMCV replication by the interferon-induced GTPase, mGBP-2: differential requirement for wild-type GTP binding domain.	GBP1 GBP2	1.23e-05	3	71	2	15717119
Pubmed	Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target.	GBP1 GBP2	1.23e-05	3	71	2	35383115
Pubmed	Role of GTP binding, isoprenylation, and the C-terminal α-helices in the inhibition of cell spreading by the interferon-induced GTPase, mouse guanylate-binding protein-2.	GBP1 GBP2	1.23e-05	3	71	2	20950129
Pubmed	Organogenic role of B lymphocytes in mucosal immunity.	CD40LG TNFRSF1A	1.23e-05	3	71	2	10583962
Pubmed	B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.	TCF4 TCF12	1.23e-05	3	71	2	8649400
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TAOK2 USP53 ERBB2 PDCD6IP NINL ANKRD50 BSN CARNS1	1.25e-05	529	71	8	14621295
Pubmed	Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.	GBP1 GBP2 TNFRSF1A	1.82e-05	25	71	3	35139355
Pubmed	Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.	BICD2 CENPF SKIL	1.82e-05	25	71	3	12522145
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	TAOK2 TCF4 ERBB2 TCF12 PDE4DIP SKIL MTUS2	1.84e-05	402	71	7	24722188
Pubmed	PAK4 functions in tumor necrosis factor (TNF) alpha-induced survival pathways by facilitating TRADD binding to the TNF receptor.	TRADD TNFRSF1A	2.46e-05	4	71	2	16227624
Pubmed	Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains.	TCF4 TCF12	2.46e-05	4	71	2	11802795
Pubmed	Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling.	SKI SKIL	2.46e-05	4	71	2	17510063
Pubmed	Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors.	TRADD TNFRSF1A	2.46e-05	4	71	2	18719121
Pubmed	Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway.	TRADD TNFRSF1A	2.46e-05	4	71	2	10911999
Pubmed	Interferon regulatory factor 1 is required for mouse Gbp gene activation by gamma interferon.	GBP1 GBP2	2.46e-05	4	71	2	7823961
Pubmed	Dnmt1/Tet2-mediated changes in Cmip methylation regulate the development of nonalcoholic fatty liver disease by controlling the Gbp2-Pparγ-CD36 axis.	GBP1 GBP2	2.46e-05	4	71	2	36609599
Pubmed	Prevention of constitutive TNF receptor 1 signaling by silencer of death domains.	TRADD TNFRSF1A	2.46e-05	4	71	2	9915703
Pubmed	SnoN oncoprotein enhances estrogen receptor-α transcriptional activity.	SKI SKIL	2.46e-05	4	71	2	22227247
Pubmed	SCL binds the human homologue of DRG in vivo.	TCF4 TCF12	2.46e-05	4	71	2	9824680
Pubmed	Epigenetic deregulation of TCF21 inhibits metastasis suppressor KISS1 in metastatic melanoma.	TCF4 TCF12	2.46e-05	4	71	2	21771727
Pubmed	Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs.	TRADD TNFRSF1A	2.46e-05	4	71	2	19781631
Pubmed	Genomic organization and chromosomal localization of a new member of the murine interferon-induced guanylate-binding protein family.	GBP1 GBP2	2.46e-05	4	71	2	10386861
Pubmed	Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway.	TRADD TNFRSF1A	2.46e-05	4	71	2	11374864
Pubmed	Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling.	TRADD TNFRSF1A	2.46e-05	4	71	2	10187805
Pubmed	Guanylate-binding protein-5 is involved in inflammasome activation by bacterial DNA but only the cooperation of multiple GBPs accounts for control of Brucella abortus infection.	GBP1 GBP2	2.46e-05	4	71	2	38404575
Pubmed	The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system.	TCF4 TCF12	2.46e-05	4	71	2	16549780
Pubmed	cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.	GBP1 GBP2	2.46e-05	4	71	2	8917111
Interaction	NME7 interactions	TCF4 RPGRIP1L MED11 NINL HUWE1 CCDC88B CEP128	1.13e-06	160	68	7	int:NME7
Interaction	RALBP1 interactions	CDC42BPG BMP2K GAS8 TNFRSF1A SKI EPN1 CCDC88B	4.64e-06	198	68	7	int:RALBP1
Interaction	PPP1R18 interactions	BICD2 TCF4 HAP1 PDE4DIP CCDC88B MTUS2	8.08e-06	141	68	6	int:PPP1R18
Interaction	TTF2 interactions	BICD2 TCF4 PDCD6IP NINL SKIL CEP128	1.03e-05	147	68	6	int:TTF2
Interaction	FAM161A interactions	BICD2 PDE4DIP GAS8 NINL CCDC88B MTUS2	1.44e-05	156	68	6	int:FAM161A
Interaction	USP2 interactions	BICD2 TRADD ERBB2 TNFRSF1A CCDC88B USP15 MTUS2	1.58e-05	239	68	7	int:USP2
Interaction	AIRIM interactions	TCF4 TCF12 PDE4DIP CCDC120 CCDC88B MTUS2	1.60e-05	159	68	6	int:AIRIM
Interaction	NEFL interactions	BICD2 TBCK PDE4DIP SYNC SKIL MTUS2	1.72e-05	161	68	6	int:NEFL
Interaction	COG6 interactions	BICD2 CENPF ODAD1 AMOTL1 GAS8 CCDC120	1.91e-05	164	68	6	int:COG6
Interaction	NDEL1 interactions	CENPF MED11 NINL CLPX CEP128 MTUS2	1.91e-05	164	68	6	int:NDEL1
Interaction	ENTPD1 interactions	PDE4DIP ASCC3 ANKRD50	1.99e-05	16	68	3	int:ENTPD1
Interaction	TXLNG interactions	BICD2 HAP1 ODAD1 NINL CEP128	2.01e-05	98	68	5	int:TXLNG
Interaction	NINL interactions	USP53 ERBB2 RPGRIP1L BMP2K CEP95 MRPS26 NINL HUWE1 CEP128	2.25e-05	458	68	9	int:NINL
Interaction	CEP95 interactions	CEP95 NINL CEP128 MTUS2	2.43e-05	50	68	4	int:CEP95
Interaction	CEP55 interactions	BICD2 PDCD6IP ODAD1 NINL CCDC120 SYNC CEP128	2.46e-05	256	68	7	int:CEP55
Interaction	HAUS1 interactions	ODAD1 PDE4DIP NINL CCDC120 CEP128 MTUS2	3.54e-05	183	68	6	int:HAUS1
Interaction	TNIK interactions	TAOK2 BICD2 TLK2 CENPF SPTBN2 PDE4DIP HUWE1 ANKRD50	4.17e-05	381	68	8	int:TNIK
Interaction	ZNF124 interactions	TCF4 HAP1 PDE4DIP MTUS2	4.69e-05	59	68	4	int:ZNF124
Interaction	MKLN1 interactions	HAP1 WNT10A CCDC120 SKI USP15	5.32e-05	120	68	5	int:MKLN1
Interaction	SDCCAG8 interactions	ODAD1 NINL CCDC120	5.40e-05	22	68	3	int:SDCCAG8
Interaction	NUDT10 interactions	TCF4 DUSP9 MTUS2	5.40e-05	22	68	3	int:NUDT10
Interaction	GID8 interactions	WNT10A CCDC120 HUWE1 SKI CEP128	5.98e-05	123	68	5	int:GID8
Interaction	TBK1 interactions	BICD2 WHRN CDC42BPG NINL SCAMP3 TNFRSF1A CEP128 USP15	6.08e-05	402	68	8	int:TBK1
Interaction	SH2D4A interactions	BICD2 PDE4DIP NINL CCDC88B MTUS2	6.46e-05	125	68	5	int:SH2D4A
Interaction	ZNF648 interactions	BICD2 HAP1 CCDC120 MTUS2	6.87e-05	65	68	4	int:ZNF648
Interaction	TCHP interactions	USP53 RPGRIP1L NINL CEP128 MTUS2	8.07e-05	131	68	5	int:TCHP
Interaction	MAP7D2 interactions	BICD2 CENPF EIF3A USP15	9.19e-05	70	68	4	int:MAP7D2
Interaction	NCKAP1 interactions	TAOK2 BICD2 TCF4 SPTBN2 HUWE1 CEP128	9.36e-05	218	68	6	int:NCKAP1
Interaction	CEP170 interactions	TEKT2 RPGRIP1L PDE4DIP NINL CCDC120 ASCC3 CEP128	9.69e-05	318	68	7	int:CEP170
Interaction	FAM74A4 interactions	TCF4 PDE4DIP MTUS2	1.01e-04	27	68	3	int:FAM74A4
Interaction	USP53 interactions	BICD2 USP53 PDCD6IP SPTBN2 NINL	1.03e-04	138	68	5	int:USP53
Interaction	TSGA10IP interactions	BICD2 GAS8 CCDC120 CCDC88B MTUS2	1.10e-04	140	68	5	int:TSGA10IP
Interaction	CCHCR1 interactions	BICD2 RPGRIP1L GAS8 NINL CCDC88B MTUS2	1.23e-04	229	68	6	int:CCHCR1
Interaction	TEAD4 interactions	AMOTL1 PDE4DIP SKI MTUS2	1.27e-04	76	68	4	int:TEAD4
Interaction	TXLNA interactions	CENPF HAP1 ODAD1 GAS8 NINL CEP128	1.44e-04	236	68	6	int:TXLNA
Interaction	FAM161B interactions	BICD2 GAS8 CCDC88B MTUS2	1.55e-04	80	68	4	int:FAM161B
Interaction	PCNT interactions	RPGRIP1L ODAD1 SPTBN2 NINL ANKRD24 HUWE1	1.62e-04	241	68	6	int:PCNT
Interaction	NEUROD1 interactions	TCF4 TCF12 HAP1	1.70e-04	32	68	3	int:NEUROD1
Interaction	CCDC146 interactions	PDE4DIP GAS8 NINL MTUS2	1.70e-04	82	68	4	int:CCDC146
Interaction	CEP170B interactions	BICD2 RPGRIP1L NINL CEP128	1.78e-04	83	68	4	int:CEP170B
Interaction	LMO4 interactions	TCF4 PDE4DIP CCDC120 KYNU MTUS2	2.00e-04	159	68	5	int:LMO4
Interaction	MSGN1 interactions	TCF4 TCF12 HAP1	2.23e-04	35	68	3	int:MSGN1
Interaction	DYNC1H1 interactions	BICD2 USP53 RPGRIP1L NINL EIF3A HUWE1 SKI USP15	2.41e-04	491	68	8	int:DYNC1H1
Interaction	AXIN1 interactions	TRIM65 SKI SKIL USP15 MTUS2	2.45e-04	166	68	5	int:AXIN1
Interaction	DYNLL2 interactions	TLK2 CDC42BPG RPGRIP1L AMOTL1 PDE4DIP BSN	2.59e-04	263	68	6	int:DYNLL2
Interaction	TMC8 interactions	TRADD TNFRSF1A	3.10e-04	8	68	2	int:TMC8
Interaction	ODF2L interactions	ERBB2 NINL CEP128	3.32e-04	40	68	3	int:ODF2L
Interaction	CKS1B interactions	TCF4 TCF12 GAS8 CCDC120	3.37e-04	98	68	4	int:CKS1B
Interaction	WDR26 interactions	WNT10A CCDC120 HUWE1 SKI USP15	3.47e-04	179	68	5	int:WDR26
Interaction	CAMSAP1 interactions	BICD2 NINL SKIL CEP128	3.51e-04	99	68	4	int:CAMSAP1
Interaction	RBM41 interactions	BICD2 NINL MTUS2	3.57e-04	41	68	3	int:RBM41
Interaction	TNRC6A interactions	BICD2 USP53 RPGRIP1L SYNM NINL TRIM65	3.63e-04	280	68	6	int:TNRC6A
Interaction	CPNE2 interactions	TCF4 SYNC EIF3A SKIL	3.64e-04	100	68	4	int:CPNE2
Interaction	MESP2 interactions	TCF4 TCF12	3.98e-04	9	68	2	int:MESP2
Interaction	ERC1 interactions	BICD2 NINL HUWE1 CEP128 USP15	4.23e-04	187	68	5	int:ERC1
Interaction	NXF1 interactions	BICD2 ERBB2 RPGRIP1L TCF12 CEP95 AMOTL1 CCDC120 ASCC3 EPN1 CEP128 USP15 KYNU MTUS2	4.90e-04	1345	68	13	int:NXF1
Interaction	CEP128 interactions	BICD2 RPGRIP1L CEP95 NINL ASCC3 CEP128	4.95e-04	297	68	6	int:CEP128
Interaction	GBP3 interactions	GBP1 GBP2	4.96e-04	10	68	2	int:GBP3
Interaction	ASCC3 interactions	PDCD6IP OTUD6B ASCC3 SKIL CEP128	5.01e-04	194	68	5	int:ASCC3
Interaction	KRT18 interactions	BICD2 USP53 TRADD RPGRIP1L PDE4DIP HUWE1 CEP128	5.20e-04	419	68	7	int:KRT18
Interaction	AEN interactions	HAP1 PDE4DIP MTUS2	5.36e-04	47	68	3	int:AEN
Interaction	GPATCH1 interactions	BICD2 RPGRIP1L NINL CEP128	5.41e-04	111	68	4	int:GPATCH1
Interaction	HOXB5 interactions	HAP1 PDE4DIP CCDC88B MTUS2	5.60e-04	112	68	4	int:HOXB5
Interaction	PIBF1 interactions	BICD2 NINL CEP128 USP15 MTUS2	5.75e-04	200	68	5	int:PIBF1
Interaction	ARHGAP36 interactions	MRPS26 HUWE1 CLPX USP15	5.98e-04	114	68	4	int:ARHGAP36
Interaction	KRT27 interactions	C21orf58 CEP95 GAS8 SYNC CCDC88B	6.01e-04	202	68	5	int:KRT27
Interaction	AFM interactions	TRADD GBP1	6.05e-04	11	68	2	int:AFM
Interaction	PCM1 interactions	BICD2 RPGRIP1L HAP1 CEP95 GAS8 NINL CEP128	6.40e-04	434	68	7	int:PCM1
Interaction	UTP14C interactions	BICD2 PDE4DIP MTUS2	6.43e-04	50	68	3	int:UTP14C
Interaction	VPS28 interactions	TCF4 TCF12 PDCD6IP SKIL	6.60e-04	117	68	4	int:VPS28
Interaction	SH3KBP1 interactions	TRADD ERBB2 RPGRIP1L PDCD6IP TNFRSF1A CCDC88B	6.74e-04	315	68	6	int:SH3KBP1
Interaction	FLAD1 interactions	BICD2 TCF4 MRPS26 DUSP9	6.81e-04	118	68	4	int:FLAD1
Interaction	SKIL interactions	GAS8 ASCC3 SKI SKIL	7.03e-04	119	68	4	int:SKIL
Interaction	ZMAT2 interactions	BICD2 ERBB2 HAP1 MTUS2	7.03e-04	119	68	4	int:ZMAT2
Interaction	WHAMMP3 interactions	BICD2 RPGRIP1L CEP95 NINL	7.03e-04	119	68	4	int:WHAMMP3
Interaction	TCF23 interactions	TCF4 TCF12	7.24e-04	12	68	2	int:TCF23
Interaction	PRPF18 interactions	BICD2 GAS8 NINL MTUS2	7.26e-04	120	68	4	int:PRPF18
Cytoband	1p22.2	GBP4 GBP1 GBP2	1.08e-05	28	70	3	1p22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr1p22	GBP4 GBP1 GBP2	1.23e-03	137	70	3	chr1p22
Cytoband	15q25.2	GOLGA6L10 GOLGA6L4	1.99e-03	43	70	2	15q25.2
GeneFamily	SKI transcriptional corepressors	SKI SKIL	3.00e-05	4	41	2	748
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN4 SPTBN2	1.05e-04	7	41	2	1113
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN4 CDC42BPG SPTBN2 DGKH	1.19e-03	206	41	4	682
Coexpression	HOWARD_B_CELL_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_18_49YO_1DY_UP	GBP4 GBP1 GBP2	6.22e-06	14	69	3	M41166
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_14_PRECICTIVE_ICB_RESPONSE	USP53 GBP4 GBP1 GBP2 ASCC3 SKIL	1.39e-05	198	69	6	MM17083
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TEKT2 RPGRIP1L CENPF C21orf58 CEP128 DNAH11	1.95e-07	157	71	6	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	MS-CD4-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	CDC42BPG TRADD GBP4 GBP1 GBP2	4.48e-06	152	71	5	b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GBP4 PROM2 ODAD1 GBP2 USP15	4.78e-06	154	71	5	9200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GOLGA6L10 HAP1 C21orf58 CD40LG ASCC3	1.19e-05	186	71	5	bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCell	B_cell_maturation-CD34+_pre-plamsa\|B_cell_maturation / Lineage and Cell class	TCF4 CCDC9B GBP4 TNFRSF1A ANKRD50	1.36e-05	191	71	5	4ee160a863d4fb9c4c9449633b9f337db8871992
ToppCell	normal_Lung-Epithelial_cells-Ciliated\|normal_Lung / Location, Cell class and cell subclass	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.39e-05	192	71	5	097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.50e-05	195	71	5	2d19148df56e99f66b596af2d7f9d0f10f9a9087
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.50e-05	195	71	5	43f0c257e4bb5c627afbdfc695c1199c672842d3
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.50e-05	195	71	5	cd6cfe3ef150a4a4575e04fc8a8213cdceefa1c4
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.50e-05	195	71	5	e22ca35bea06aa95ff2cc771632969f5e7229ffc
ToppCell	Mild-CD4+_T_activated\|Mild / Disease group and Cell class	TRADD GBP4 CD40LG GBP1 GBP2	1.54e-05	196	71	5	daa1c3322d81e649161e889e1d78451d2d425d09
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TEKT2 CENPF C21orf58 ODAD1 DNAH11	1.61e-05	198	71	5	f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCell	Sepsis-URO-Lymphocyte-T/NK-CD4+_CTL\|URO / Disease, condition lineage and cell class	GOLGA6L10 SYNM CD40LG ANKRD24 CEP128	1.61e-05	198	71	5	c53405a8d082fbd10131a6ec88b69fdd835f2925
ToppCell	distal-Epithelial-Ciliated-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.61e-05	198	71	5	d30d6c6a0a78b7571318b5b2a0186df96dd0f5a9
ToppCell	medial-Epithelial-Ciliated-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.65e-05	199	71	5	526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell	BAL-Mild-cDC_1\|Mild / Compartment, Disease Groups and Clusters	TCF4 GBP4 GBP1 GBP2 USP15	1.65e-05	199	71	5	c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCell	medial-Epithelial-Ciliated\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.65e-05	199	71	5	a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell	distal-1-Epithelial-Ciliated\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.65e-05	199	71	5	4120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCell	medial-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.65e-05	199	71	5	c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell	distal-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.65e-05	199	71	5	97b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.69e-05	200	71	5	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.69e-05	200	71	5	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	Biopsy_Other_PF-Epithelial-Differentiating_Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.69e-05	200	71	5	f7b4581d958afbd68f9045af619aaca0ab463439
ToppCell	Neuronal-Inhibitory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TCF4 ZNF536 TCF12 AMOTL1 NINL	1.69e-05	200	71	5	9ff8647e2de0b538e15929dca88ebb20ff7ab043
ToppCell	LPS_IL1RA\|World / Treatment groups by lineage, cell group, cell type	TCF4 DGKH EIF3A ASCC3 SKIL	1.69e-05	200	71	5	a02fa5b3c4723a6eaa3c685588666c710478dd25
ToppCell	Neuronal-Inhibitory-iA\|Neuronal / cells hierarchy compared to all cells using T-Statistic	TCF4 ZNF536 TCF12 HAP1 NINL	1.69e-05	200	71	5	5ef4a3dc18a44292184a59ced916183c0699b01e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 ODAD1 PCSK1N DNAH11	1.69e-05	200	71	5	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TLK2 TCF12 SKIL CEP128	9.20e-05	148	71	4	10dcbdb47cac908648d9d652c8095b536db19b8a
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_2\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	SPTBN4 DCHS2 SPTBN2 WNT10A	1.05e-04	153	71	4	a44da11a913b19edde6c5d1d6e625c24b20ecbfd
ToppCell	Ciliated_cells-A-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 ODAD1 DUSP9 DNAH11	1.07e-04	154	71	4	3b938e23324f7edb56797b4a76fb96ff588142cf
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GBP4 PROM2 GBP2 USP15	1.07e-04	154	71	4	b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN2 BSN EPN1 KYNU	1.10e-04	155	71	4	72a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|367C / Donor, Lineage, Cell class and subclass (all cells)	WHRN WNT10A GBP2 USP15	1.16e-04	157	71	4	f1c6c313836352271033d23efd31b0f0a8a09e02
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP95 DUSP9 CCDC120 KYNU	1.27e-04	161	71	4	ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP95 DUSP9 CCDC120 KYNU	1.27e-04	161	71	4	0089d7bb305c592392791862a3341fc92af8f3e2
ToppCell	5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 NINL PCSK1N MTUS2	1.30e-04	162	71	4	478cf560ef33c5c324142c76417447d4a571a2c9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BICD2 GOLGA6L10 C21orf58 CD40LG	1.34e-04	163	71	4	e4077e587895c85bc806be05ff5d451088e39468
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GBP4 CENPF GBP1 TNFRSF1A	1.34e-04	163	71	4	d005115aa1e1458b51de7eb719794617a4168608
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	ZNF536 GBP4 GBP1 BSN	1.37e-04	164	71	4	362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCell	T_cells-TFH-like_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	WHRN CD40LG WNT10A DGKH	1.37e-04	164	71	4	b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Interneuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TCF4 ZNF536 PDE4DIP	1.40e-04	63	71	3	c10d344bf32a091deb79e1f128f7dd5e9f4abaa3
ToppCell	10x5'-Liver-Hematopoietic_progenitors\|Liver / Manually curated celltypes from each tissue	CENPF C21orf58 ODAD1 ANKRD50	1.43e-04	166	71	4	ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell	10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|Liver / Manually curated celltypes from each tissue	CENPF C21orf58 ODAD1 ANKRD50	1.43e-04	166	71	4	a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	TEKT2 RPGRIP1L GAS8 DNAH11	1.47e-04	167	71	4	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TCF4 CENPF C21orf58 CEP128	1.47e-04	167	71	4	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	Ciliated_cells-A-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ZNF536 TEKT2 ODAD1 DNAH11	1.47e-04	167	71	4	edb722ee9b6ccd00fb038f702be8664020932659
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TEKT2 SPTBN2 WNT10A CARNS1	1.50e-04	168	71	4	e870d2e69316406f45112ed0bf324b24f902a99e
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TEKT2 SPTBN2 WNT10A CARNS1	1.50e-04	168	71	4	403aba73a0f9ffb32252288d075fad8a588ca440
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	WHRN ODAD1 DGKH DNAH11	1.53e-04	169	71	4	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	Immune_cells-Dendritic_cells\|World / Lineage and Cell class	TCF4 GBP4 DUSP9 KYNU	1.57e-04	170	71	4	094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DCHS2 AMOTL1 DGKH ANKRD50	1.57e-04	170	71	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	PROM2 WNT10A ANKRD50 SKIL	1.60e-04	171	71	4	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TRADD PROM2 CD40LG EIF3A	1.60e-04	171	71	4	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERBB2 SPTBN2 TBCK PCSK1N	1.64e-04	172	71	4	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 C21orf58 GAS8 MTUS2	1.64e-04	172	71	4	73e9b29b1c6b8b016b495a0d20336d0c0761e5e2
ToppCell	droplet-Lung-nan-3m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 DUSP9 CEP128 KYNU	1.68e-04	173	71	4	1b9b4e165121b08ef15a93fca6bea875cae69f19
ToppCell	droplet-Lung-nan-3m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 DUSP9 CEP128 KYNU	1.68e-04	173	71	4	c25f24d7b672c9686d31ebc8d263042282f520fd
ToppCell	wk_20-22-Hematologic-Myeloid-CXCL9+_Mac\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	GBP4 GBP1 GBP2 KYNU	1.75e-04	175	71	4	48f5bdbfc1ba40c3fb6411f12a69e61da2138296
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tfh\|blood / Manually curated celltypes from each tissue	CD40LG WNT10A DGKH CARNS1	1.75e-04	175	71	4	d7e24ac683ff36f7ce3d1151353d3d4a6f2b63bf
ToppCell	Club_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	ERBB2 PROM2 SPTBN2 PCSK1N	1.79e-04	176	71	4	88c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell	PBMC-Severe-cDC_2\|Severe / Compartment, Disease Groups and Clusters	RPGRIP1L SYNM CD40LG	1.83e-04	69	71	3	0fab02d29408415d3aa1f42a55a2e37b458c4030
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 TEKT2 WNT10A DGKH	1.83e-04	177	71	4	291231b1520c135e92739e201495fe1935efa927
ToppCell	(1)_T_regulatory\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	WHRN WNT10A GBP2 USP15	1.83e-04	177	71	4	5cda56b10df1ee8971ce8470d52062e01b703a4e
ToppCell	Ciliated_cells-B-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ZNF536 TEKT2 C21orf58 DNAH11	1.83e-04	177	71	4	c38138fb5ad9766c2d240811210c854338cd612e
ToppCell	343B-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TAOK2 CENPF C21orf58 CEP128	1.87e-04	178	71	4	c7e890cd02206c516cf1d7692ea7abc8ce746482
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|343B / Donor, Lineage, Cell class and subclass (all cells)	GOLGA6L10 HAP1 C21orf58 CD40LG	1.87e-04	178	71	4	ec6364432d37a32f5152d36d89f5e96dddb72a9d
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	TRADD GBP4 GBP1 GBP2	1.91e-04	179	71	4	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	Ciliated_cells-A-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 C21orf58 ODAD1 PCSK1N	1.91e-04	179	71	4	0e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 RPGRIP1L TBCK CCDC120	1.95e-04	180	71	4	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF4 BMP2K DUSP9 KYNU	1.95e-04	180	71	4	df60970520fba2ac0639faa54096766d07418ca4
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 C21orf58 ODAD1 PCSK1N	1.95e-04	180	71	4	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 RPGRIP1L TBCK CCDC120	1.95e-04	180	71	4	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF536 RPGRIP1L TBCK CCDC120	1.95e-04	180	71	4	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TEKT2 C21orf58 ODAD1 DNAH11	1.99e-04	181	71	4	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	TCF12 DGKH HUWE1 USP15	1.99e-04	181	71	4	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	GOLGA6L10 HAP1 C21orf58 CD40LG	2.04e-04	182	71	4	c98da2db197b1531204e116600ff51891e5c17af
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	TEKT2 C21orf58 ODAD1 DNAH11	2.04e-04	182	71	4	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Ciliated_cells-B-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 C21orf58 ODAD1 PCSK1N	2.04e-04	182	71	4	e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	GBP4 GBP1 GBP2 SKIL	2.08e-04	183	71	4	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TCF4 GBP4 BMP2K GBP1	2.08e-04	183	71	4	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	B_cells-ABCs\|B_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	BMP2K GBP1 GBP2 SYNC	2.08e-04	183	71	4	bf9c6fe3ce4e44e4056027257eab8448c39c4fb8
ToppCell	10x5'v1-week_17-19-Lymphocytic_T-T_NK-Treg\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	USP53 WHRN CD40LG GBP2	2.08e-04	183	71	4	5fb933acfe6bc555c90dba71e75d4be658763945
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TEKT2 ODAD1 PCSK1N DNAH11	2.08e-04	183	71	4	58847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCell	wk_15-18-Hematologic-Myeloid-CXCL9+_Mac\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	GBP4 GBP1 GBP2 KYNU	2.08e-04	183	71	4	99a36e9c74346b619b3b87d8d6bbf9b4b797c821
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DGKH EIF3A ASCC3 USP15	2.12e-04	184	71	4	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SPTBN2 PCSK1N ANKRD24 MTUS2	2.12e-04	184	71	4	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	10x5'-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	GBP2 DGKH CEP128 USP15	2.12e-04	184	71	4	22c15ce30171c687ab564f4383ae74d38b759272
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TEKT2 C21orf58 ODAD1 DNAH11	2.12e-04	184	71	4	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TCF4 ZNF536 HAP1 NINL	2.17e-04	185	71	4	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	TEKT2 C21orf58 ODAD1 DNAH11	2.17e-04	185	71	4	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	TCF4 HAP1 PROM2 KYNU	2.17e-04	185	71	4	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TBCK NINL KYNU DNAH11	2.21e-04	186	71	4	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TBCK NINL KYNU DNAH11	2.21e-04	186	71	4	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TEKT2 C21orf58 PCSK1N DNAH11	2.26e-04	187	71	4	88f785932e67c613db0dda84496de351359ed962
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TEKT2 C21orf58 ODAD1 DNAH11	2.26e-04	187	71	4	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	390C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	TEKT2 C21orf58 PCSK1N DNAH11	2.26e-04	187	71	4	8896a00b30d11b90ca42726d4e122174a30b161b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 SPTBN2 BSN EPN1	2.26e-04	187	71	4	e04a84989d624378141042768383b9c846901f2d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CENPF C21orf58 CCDC88B CEP128	2.26e-04	187	71	4	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 SPTBN2 BSN EPN1	2.26e-04	187	71	4	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN4 SPTBN2 BSN EPN1	2.26e-04	187	71	4	2f153b203fe79f206319603cf94d3a03ab49a05d
Disease	Primary ciliary dyskinesia	CENPF ODAD1 GAS8 DNAH11	1.35e-06	36	67	4	cv:C0008780
Disease	Primary Ciliary Dyskinesia	RPGRIP1L ODAD1 GAS8 DNAH11	4.02e-06	47	67	4	C4551720
Disease	Pitt-Hopkins syndrome (implicated_via_orthology)	TCF4 TCF12	1.52e-05	3	67	2	DOID:0060488 (implicated_via_orthology)
Disease	HELLP syndrome (is_marker_for)	ERBB2 CD40LG	3.04e-05	4	67	2	DOID:13133 (is_marker_for)
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN4 SPTBN2	3.04e-05	4	67	2	DOID:0050882 (implicated_via_orthology)
Disease	insomnia measurement	TCF4 ZNF536 TCF12 ASCC3 MTUS2 DNAH11	5.10e-04	443	67	6	EFO_0007876
Disease	lupus nephritis (is_marker_for)	CD40LG TNFRSF1A	6.76e-04	17	67	2	DOID:0080162 (is_marker_for)
Disease	cortical surface area change measurement, age at assessment	ZNF536 USP15	8.47e-04	19	67	2	EFO_0008007, EFO_0021503
Disease	obesity (implicated_via_orthology)	TCF4 DCHS2 TCF12 PCSK1N	1.47e-03	215	67	4	DOID:9970 (implicated_via_orthology)
Disease	response to antineoplastic agent	CENPF PDE4DIP MTUS2	1.50e-03	99	67	3	GO_0097327
Disease	bipolar disorder	TAOK2 WHRN ERBB2 SPTBN2 DGKH HUWE1	1.98e-03	577	67	6	MONDO_0004985
Disease	Ciliopathies	WHRN RPGRIP1L DNAH11	2.03e-03	110	67	3	C4277690
Disease	self rated health	TCF4 BSN	2.26e-03	31	67	2	EFO_0004778

Protein segments in the cluster

Peptide	Gene	Start	Entry
LEDVRLVHRDLAARN	ERBB2	836	P04626
LLDEIHREKRDLLEE	CEP128	926	Q6ZU80
LELLELDHEQTRRGR	BICD2	796	Q8TD16
DRLEHLQRELEQAAL	CCDC88B	886	A6NC98
NRELLERSLESRDHL	CCDC88B	1256	A6NC98
LHRRLDKIEDERNLH	CD40LG	46	P29965
DRLLRHVEARDLIEF	CLPX	476	O76031
HRRDEENARLLAELV	CARNS1	446	A5YM72
DLLALRLHRVEDDVR	DNAH11	1431	Q96DT5
LHDFNRDLRDRLETA	AMOTL1	511	Q8IY63
RTLLDRGLDENHRDD	ANKRD50	831	Q9ULJ7
ASEHRRLQEEALELR	ANKRD24	916	Q8TF21
LDREFDLLRSNRLEE	BMP2K	641	Q9NSY1
TLDNEELRRHSLERA	MTUS2	166	Q5JR59
LERVLDREEERVHHL	PCDHGA7	196	Q9Y5G6
DLRQELDRLHRELAE	CDC42BPG	486	Q6DT37
SREELEDRFLRLHDE	RPGRIP1L	46	Q68CZ1
IEDRLERLDDAIHVL	TCF4	386	P15884
LRELDRDLRLVEHES	BSN	2941	Q9UPA5
ADALRRLHELEEQLR	CCDC120	151	Q96HB5
RLHELEEQLRDVRAR	CCDC120	156	Q96HB5
EREQIDLARLARHRD	CCDC9B	241	Q6ZUT6
ARALAHLLEAERQER	PCSK1N	76	Q9UHG2
RNREILDESLRLLDE	PDCD6IP	446	Q8WUM4
EDRLDRLDDAIHVLR	TCF12	401	Q99081
QLLDFERSLRLEERH	DUSP9	336	Q99956
QELLDLHRDSEREAI	GBP1	351	P32455
LREQEERLHEQEERL	GOLGA6L3	271	A6NEY3
LCEQEERLREHEERL	GOLGA6L4	236	A6NEF3
LHEQEERLREQEERL	GOLGA6L4	271	A6NEF3
ETLQELLDLHRDSER	GBP2	346	P32456
LLDLHRDSEREAIEV	GBP2	351	P32456
LREQEERLHEQEERL	GOLGA6L10	201	A6NI86
LREQEERLHEQEERL	GOLGA6L19	201	H0YKK7
EERENLLREHERLLK	GBP4	551	Q96PP9
RHLELLLRDLEDSRG	NLRX1	931	Q86UT6
DIRGAELLHLERRDL	DGKH	1176	Q86XP1
NHLEFLRDEELEERR	HUWE1	2676	Q7Z6Z7
NAALREELDLLRIDR	ODAD1	136	Q96M63
LRRLDREEAAAHRLQ	DCHS2	251	Q6V1P9
TEELDEEEQLLRRHR	OTUD6B	6	Q8N6M0
NENLRLLHVIEDRDR	CENPF	1781	P49454
ERLAEERHNRLEERK	EIF3A	781	Q14152
RDLLQRLREQHLLDE	C21orf58	141	P58505
FLDREALRLREENRL	CCDC166	61	P0CW27
LRLLEEENHQLREEA	HAP1	321	P54257
LQDEIEEALRRHDLL	CEP95	611	Q96GE4
DEDRLREERAHALKT	EPN1	136	Q9Y6I3
EELDRRERELQHAAL	SCAMP3	111	O14828
LANERLRALEDIERE	MED11	6	Q9P086
HLEDENRILQGELRR	DRP2	791	Q13474
LHELRIARLRQEERE	MRPS26	116	Q9BYN8
EERDQLIHELVLLRE	SYNC	191	Q9H7C4
RLRDEELAELEDALR	TRADD	146	Q15628
LRQRLDHAEADRQEL	SKIL	636	P12757
DALRRELRELQRLDA	SYNM	86	O15061
AELQEDIRHLEEDLR	TEKT2	291	Q9UIF3
LLALESRLRGEREEH	TAOK2	506	Q9UL54
QDLERFDHLVLRREI	WHRN	486	Q9P202
VDLRENDRLEFHRLS	NINL	1076	Q9Y2I6
HAEADREQLRADLLR	SKI	676	P12755
ADLLREREAREHLEK	SKI	686	P12755
ELERLERVRNLHIRE	TLK2	426	Q86UE8
RLLILDEVHLLHEDR	ASCC3	606	Q8N3C0
RKDLGRHRDLVDEDL	USP53	471	Q70EK8
EHERELALRTELIRQ	SPTBN2	406	O15020
ELAGERRERLQEHLR	SPTBN2	1681	O15020
QEHLRLCQLRRELDD	SPTBN2	1691	O15020
AIREHRDRLLELLQE	PROM2	286	Q8N271
TRHIRFDDRQLRLDE	USP15	731	Q9Y4E8
HEREAALRAELIRQE	SPTBN4	411	Q9H254
AEHCERSLEDLLRER	TBCK	71	Q8TEA7
RVREENRLLHELEER	ZNF536	191	O15090
NRLLHELEERAILRD	ZNF536	196	O15090
DEEAFRRKLHRLQLD	WNT10A	166	Q9GZT5
ECRLHERALLDAERL	TRIM65	121	Q6PJ69
RRLGLSDHEIDRLEL	TNFRSF1A	376	P19438
LRDELDLRRKTELHE	GAS8	196	O95995
DERVALHLDEEDKLR	KYNU	26	Q16719
LAVRERDHDLERLRD	PDE4DIP	511	Q5VU43
EHLGEIRNLRQRLEE	PDE4DIP	1846	Q5VU43