Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

1.74e-06884218GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

3.99e-051353218GO:0004888
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

GPR182 NPY5R RXFP2

3.52e-04133213GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

GPR182 NPY5R RXFP2

4.09e-04140213GO:0001653
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

3.94e-051395218GO:0007186
HumanPhenoAbnormality of cardiac conduction

ADAMTS19 ZFHX3 RYR2

6.94e-0445233HP:0001665
HumanPhenoAtrial fibrillation

ZFHX3 RYR2

8.75e-048832HP:0005110
HumanPhenoAtrial arrhythmia

ZFHX3 RYR2

9.78e-049332HP:0001692
HumanPhenoPalpitations

ADAMTS19 RYR2

1.27e-0310632HP:0001962
HumanPhenoArrhythmia

ADAMTS19 ZFHX3 RYR2

1.27e-0355333HP:0011675
HumanPhenoAbnormality of cardiovascular system electrophysiology

ADAMTS19 ZFHX3 RYR2

1.47e-0358033HP:0030956
HumanPhenoSupraventricular tachycardia

ZFHX3 RYR2

1.63e-0312032HP:0004755
HumanPhenoSupraventricular arrhythmia

ZFHX3 RYR2

2.03e-0313432HP:0005115
HumanPhenoTachycardia

ZFHX3 RYR2

4.01e-0318932HP:0001649
HumanPhenoVentricular arrhythmia

ZFHX3 RYR2

6.91e-0324932HP:0004308
DomainGPCR_Rhodpsn_7TM

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

3.54e-07670218IPR017452
Domain7tm_1

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

3.83e-07677218PF00001
DomainG_PROTEIN_RECEP_F1_1

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

4.19e-07685218PS00237
DomainG_PROTEIN_RECEP_F1_2

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

4.47e-07691218PS50262
DomainGPCR_Rhodpsn

GPR135 OR51Q1 OR56B4 OR4C12 GPR182 NPY5R RXFP2 GPR20

4.52e-07692218IPR000276
DomainOlfact_rcpt

OR51Q1 OR56B4 OR4C12

9.28e-03393213IPR000725
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

RYR2 GPR182 RXFP2

7.77e-04154173MM15974
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

RYR2 GPR182 RXFP2

8.07e-04156173M39475
PathwayWP_GPCRS_ODORANT

GPR135 GPR182 GPR20

8.22e-04157173MM15872
Pubmed

Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.

RYR2 WDR64

7.21e-052022219626040
Cytoband1q43

RYR2 WDR64

2.76e-04512221q43
CytobandEnsembl 112 genes in cytogenetic band chr1q43

RYR2 WDR64

4.07e-0462222chr1q43
CytobandEnsembl 112 genes in cytogenetic band chr16q22

CMTR2 ZFHX3

3.46e-03183222chr16q22
Cytoband11p15.4

OR51Q1 OR56B4

4.12e-0320022211p15.4
CytobandEnsembl 112 genes in cytogenetic band chr11p15

OR51Q1 OR56B4

2.96e-02564222chr11p15
GeneFamilyG protein-coupled receptors, Class A orphans

GPR135 GPR182 GPR20

7.12e-0578193262
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 RYR2 WDR64 RXFP2

8.79e-07160214c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 RYR2 WDR64 RXFP2

8.79e-0716021425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellTCGA-Adrenal-Solid_Tissue_Normal-Adrenal_medulla_normal-Adrenal_medulla-4|TCGA-Adrenal / Sample_Type by Project: Shred V9

GPR182 NPY5R RXFP2

1.83e-051102135030985d583a7fbd2fdac2a874c64bbb44bcd829
ToppCellTCGA-Adrenal-Solid_Tissue_Normal-Adrenal_medulla_normal|TCGA-Adrenal / Sample_Type by Project: Shred V9

GPR182 NPY5R RXFP2

1.83e-0511021378a41043c7fd58b78f4740dc81ff5b493598a3a6
ToppCellTCGA-Adrenal-Solid_Tissue_Normal-Adrenal_medulla_normal-Adrenal_medulla|TCGA-Adrenal / Sample_Type by Project: Shred V9

GPR182 NPY5R RXFP2

1.83e-0511021326135f7f980af7888c882c9e36294bc4d5093ec7
ToppCellTCGA-Adrenal-Solid_Tissue_Normal|TCGA-Adrenal / Sample_Type by Project: Shred V9

GPR182 NPY5R RXFP2

1.83e-05110213e09b4f1b536c79389cd8ed898314b8250a643a37
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 ZFHX3 RYR2

5.19e-051562136365b69ede98bc866e996bc52736b00401aacf6f
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPC1 RYR2 GPR20

6.14e-051652138a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBC1D26|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OR51Q1 SCGB1D4 ZFHX3

7.06e-0517321337457ce2b0bb2a56d6e56f6fd9c668eb40c70ae0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

7.31e-05175213316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

7.31e-05175213a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 ZFHX3 RYR2

8.34e-051832138a799807fbf24456a9811e0c64068187940a2f71
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX3 RXFP2 GPR20

8.48e-0518421389ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 ZFHX3 RYR2

8.48e-05184213689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 ZFHX3 RYR2

8.48e-05184213327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFHX3 RXFP2 GPR20

8.48e-0518421334c84ac9a32eaf96f45b79485119cad65905817d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX3 RYR2 GPR20

8.75e-05186213a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX3 RYR2 GPR20

8.75e-051862134780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZFHX3 RYR2 GPR20

8.89e-0518721386250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RYR2 PFKFB1 GPR20

9.03e-05188213a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX3 RYR2 GPR20

9.18e-05189213975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.18e-051892137fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.18e-0518921306b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.18e-051892132cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.18e-05189213127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX3 RYR2 GPR20

9.32e-0519021373d94fbae92029745989a8712eed8b99fd84c193
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZFHX3 RYR2 GPR20

9.47e-051912137853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.47e-0519121304c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.62e-05192213bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.62e-05192213b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPC1 ZFHX3 GPR20

9.76e-051932137631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPC1 ZFHX3 GPR20

9.76e-051932138d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.91e-05194213ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2 GPR20

9.91e-051942135c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX3 RYR2 GPR20

1.02e-041962136d7179decea512dd49bb2d5f6a4f5989349d52a9
ToppCell5'-Adult-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX3 RYR2 GPR20

1.02e-04196213ce6f7ddb8104471dc90347f427486379914d63b4
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZFHX3 RYR2 GPR20

1.02e-04196213754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPC1 RYR2 GPR20

1.04e-041972133f078be0b0f5e16edfb6d517beb20ac6178767f0
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX3 RYR2 GPR20

1.04e-04197213d16bb765afdc02406ffd7ce6a75bae72b66db66c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFHX3 RYR2 GPR20

1.04e-0419721368c23c23b6924892f4c238cf2f5abc7927e04fbc
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZFHX3 RYR2 GPR20

1.07e-04199213c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPC1 GPR135 ADAMTS19

1.08e-042002138a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCellParenchymal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

GPC1 GPR135 ADAMTS19

1.08e-042002134c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

WDR64 RXFP2

3.86e-04622123eec7f31de7cc24762c5b180475650676437dc76
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

WDR64 RXFP2

3.86e-0462212f5f5441f5be00ab80a7827c4af1afbe45c552c2e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

WDR64 RXFP2

3.86e-04622126e81a37b9defa96528654bee1b23152108d9c0b7
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Cplx3_(Deep_layer_pyramidal_cells--Cortical_Subplate)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ADAMTS19 RXFP2

6.10e-0478212869fcbc0c308164101c0e4e0494c6a75c2f6f94e
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7-Slc17a8.Syt6-Cplx3_(Deep_layer_pyramidal_cells--Cortical_Subplate)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ADAMTS19 RXFP2

6.10e-047821246e31ebb3afc08bf414a5793cd9b4320bf4375c5
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Slc17a7-Slc17a6.Calb1-Rorb-Il1rapl2_(Layer_5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADAMTS19 WDR64

6.41e-0480212402aba070f0728ebda9db7a8fa85441533755ff4
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADAMTS19 RXFP2

6.58e-048121220796e59cdeb398e7772f4356578d74a33405f71
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Hist1h2al))|Striatum / BrainAtlas - Mouse McCarroll V32

ADAMTS19 PFKFB1

6.74e-04822123cee9ee752128dd91e9abc05c9f97b17e64a2a76
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Choriocarcinoma,_Embryonal_Carcinoma,_Immature_Teratoma,_Mature_Teratoma,_Yolk_Sac_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

OR51Q1 OR4C12

9.41e-04972120f31f58ed031183726b7ad8f9133b50ca1bb1a9a
ToppCellDendritic_Cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

RXFP2 GPR20

9.99e-04100212bb7bd11e28be830f381144d4a6f29a86da59d9fa
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PFKFB1 GPR20

9.99e-04100212f6359e4b3926ce5f0980c994d7271f0743ce4c41
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Cnn1_(Mural.Rgs5Acta2.Cnn1)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PFKFB1 GPR20

9.99e-041002125bbcb307adf73cb8a496773f014d5cf2b36f446c
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Fos_(Mural.Rgs5Acta2.Fos)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PFKFB1 GPR20

1.10e-0310521273639bfa677c7bb9e5166aa09eabaf1b05bb89a0
ToppCellSubstantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1-MURAL_Mural.Rgs5Acta2.Fos_(Mural.Rgs5Acta2.Fos)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

PFKFB1 GPR20

1.10e-0310521284b639eb44f71d1e12bb7850b9063d80e73cb741
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZFHX3 RYR2

1.10e-031052128f31edf4183587f5b53941475453c5aa49f10bbd
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Il33_(Il33)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR182 PFKFB1

1.14e-03107212d446ffbe93cd49669f1cf91411aae07cc15d9e2a
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Il33_(Il33)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GPR182 PFKFB1

1.14e-031072125c9e745d0b08a4aa1f3a93f9cc094fac57061a30
ToppCellThalamus|World / BrainAtlas - Mouse McCarroll V32

ADAMTS19 ZFHX3

1.34e-031162125ddfb2dd5459ff6d7ae38163a38eae64fda283b7
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF182 WDR64

1.39e-031182128d96a4879b28979fa04fbaeffa271a6b9ecbe867
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-7|TCGA-Stomach / Sample_Type by Project: Shred V9

GPR135 RYR2

1.60e-031272125e4d110cc6e68cd8fc7a4771a65e6f8cd83e7721
ToppCellTCGA-Endometrium|World / Sample_Type by Project: Shred V9

ADAMTS19 SCGB1D4

1.68e-03130212101d9bf4bdf10c4f5e852067297a3bc6e735d794
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-2|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

GPR135 RYR2

1.73e-03132212a8e7e7f38af095d63e221bcc06a1e5147bb6e467
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)|Cerebellum / BrainAtlas - Mouse McCarroll V32

CMTR2 GPR20

1.78e-031342121fa13185a4dfb4563473184c0c4f449011d88631
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Gpr139|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 RNF182

1.78e-03134212917b8951dd4c870b6b92f2e73e02dac884330c30
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

CMTR2 GPR20

1.78e-031342121ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Cerebellum / BrainAtlas - Mouse McCarroll V32

CMTR2 GPR20

1.78e-031342128a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NPY5R GPR20

1.97e-03141212a32947b13e888850c979a54c137512e4b96d2f36
ToppCellGlobus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Pappa2_(Mural.Rgs5Acta2.Pappa2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NPY5R GPR20

1.97e-031412122cb651d63466fdcce011d1dd8de409ef439d03e7
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RNF182 GPR20

2.17e-03148212f58804d24fe524b42b5090c8658050ea4b14793e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RYR2 GPR20

2.28e-03152212ee329249a034a969a16b26a224aa04249d67382d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RYR2 GPR20

2.28e-03152212bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RXFP2 GPR20

2.28e-03152212d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RXFP2 GPR20

2.28e-03152212d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2

2.28e-031522120cb5f4dfae04e3f4eba502bbf229007d5fa3884d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 RYR2

2.28e-03152212ba89ffb5a8bb33c188f854f54b39123b6d73496a
ToppCellBac-SEP-Lymphocyte-T_NK-CD4_TEM|Bac-SEP / Disease, Lineage and Cell Type

PFKFB1 WDR64

2.40e-03156212ef6bad99bcb30956863cd490c613e251f3b27ba0
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS19 RYR2

2.43e-03157212bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellfacs-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 ZFHX3

2.43e-03157212a84377028c661f8f3ecae0f6082abdd859faf0c8
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 GPR20

2.46e-0315821208806240228c5b780f5aef92ce2c278ae4d797cc
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

RYR2 GPR20

2.46e-031582128d64c0c9de910a3f4658778642d183c8b9b6f6a2
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 GPR20

2.46e-03158212496b6988f7b3439968351840ae22f56ffa1643f1
ToppCellfrontal_cortex-Non-neuronal-smooth_muscle_cell-SMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 GPR20

2.46e-031582125b3d30f92b619f14a7b48502170000fa5783358a
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMTR2 GPR20

2.49e-031592127ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PFKFB1 RXFP2

2.52e-031602122d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

ZFHX3 GPR20

2.52e-0316021229c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PFKFB1 RXFP2

2.52e-031602128bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RNF182 RYR2

2.52e-031602120293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RNF182 RYR2

2.52e-031602123eaae86fa08f7651021316f8e5811bf48055591e
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

RYR2 GPR20

2.52e-03160212fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 WDR64

2.56e-03161212b9a17f41426bf715f30bf544a6795afaf37a3aa6
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

ZFHX3 GPR20

2.56e-0316121247b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR2 WDR64

2.56e-03161212f7a89c481f789f624102857be722c95fbeb47595
ToppCelldroplet-Heart-4Chambers|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPC1 GPR182

2.59e-031622125625ec6dae204d5537883f05ea546970628d10bb
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

RYR2 WDR64

2.62e-0316321219c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RNF182 GPR20

2.62e-0316321251dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZFHX3 GPR20

2.65e-031642129eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZFHX3 GPR20

2.65e-0316421243630a448f4369fa9e4e3eccdf3b9f29cec16c39
Diseasehaptoglobin measurement

CMTR2 ZFHX3

1.00e-0421212EFO_0004640
Diseaseword reading

ZFHX3 MMS22L

9.77e-0465212EFO_0005300
Diseasereaction time measurement

GPC1 ZFHX3 LIMK2 MMS22L

1.08e-03658214EFO_0008393
Diseaseautosomal dominant compelling helio-ophthalmic outburst syndrome

ZFHX3 MMS22L

1.37e-0377212EFO_0007887
Diseasepulmonary hypertension (biomarker_via_orthology)

RYR2 GPR182

1.47e-0380212DOID:6432 (biomarker_via_orthology)
Diseaseorofacial cleft, sex interaction measurement

SLCO6A1 ZFHX3

1.70e-0386212EFO_0008343, MONDO_0000358
Diseaserisk-taking behaviour

CMTR2 ZFHX3 MMS22L RYR2

1.88e-03764214EFO_0008579
Diseasetaste liking measurement

ZFHX3 LIMK2 MMS22L

2.52e-03388213EFO_0010155
Diseaselung disease severity measurement

SCGB1D4 ZFHX3

3.17e-03118212EFO_0007744
Diseasemood instability measurement

CMTR2 MMS22L

3.71e-03128212EFO_0008475
Diseasemean arterial pressure

SLCO6A1 ZFHX3 MMS22L

5.10e-03499213EFO_0006340
Diseaserisky sexual behaviour measurement

ZFHX3 MMS22L

6.38e-03169212EFO_0007877
Diseasemultiple sclerosis

ZFHX3 LIMK2 MMS22L

8.24e-03594213MONDO_0005301
Diseasebrain volume measurement

GPR135 ZFHX3 MMS22L

8.28e-03595213EFO_0006930
Diseasealcohol use disorder (implicated_via_orthology)

RYR2 NPY5R

8.40e-03195212DOID:1574 (implicated_via_orthology)
Diseasecolorectal health

ZFHX3 RYR2

8.90e-03201212EFO_0008460
DiseaseObesity

ZFHX3 NPY5R

9.25e-03205212C0028754
Diseasevital capacity

ADAMTS19 ZFHX3 MMS22L RYR2

1.04e-021236214EFO_0004312
Diseasecortical surface area measurement, neuroimaging measurement

ADAMTS19 ZFHX3

1.12e-02227212EFO_0004346, EFO_0010736
Diseasediastolic blood pressure, systolic blood pressure

GPR135 ZFHX3 RYR2

1.14e-02670213EFO_0006335, EFO_0006336
Diseaseamino acid measurement

ADAMTS19 RYR2 RXFP2

1.18e-02678213EFO_0005134

Protein segments in the cluster

PeptideGeneStartEntry
ICHQAVMRCLLAYFL

PFKFB1

391

P16118
LCCGLYFCRMFSQHI

ERVPABLB-1

466

P60509
FLNMHCSILFLTCIC

GPR20

131

Q99678
EHCSINLMYLLNCCF

CMTR2

281

Q8IYT2
MRLTHICCCCLLYQL

ADAMTS19

1

Q8TE59
MHVHVCVCLCVCIYT

OVOS1

1

Q6IE37
ILLTVMACDCYVAIC

OR4C12

111

Q96R67
CSRAVMKLVYCAHCL

GPC1

246

P35052
YHPECFACMSCKVII

LIMK2

91

P53671
QLRMYLHCCLTLCDF

MMS22L

401

Q6ZRQ5
VLLAMSVDCYVAICC

OR51Q1

116

Q8NH59
HCFFCIESGIFLCMA

OR56B4

111

Q8NH76
LLMCFCHYHICKTVR

GPR135

291

Q8IZ08
MCLLLQYLCDCQVRH

RYR2

1906

Q92736
VYCICHLLGMMSCCL

NPY5R

406

Q15761
HCLLLCAYVAVFVMC

GPR182

256

O15218
ILCCADCLMGVYLFF

RXFP2

456

Q8WXD0
RCFMIFYCILLICQG

SLCO6A1

106

Q86UG4
LMVYGFCQCVCHEFL

RNF182

226

Q8N6D2
CLLMVSLALCCYQAH

SCGB1D4

6

Q6XE38
SLLALIEMVVYCCFC

USP24

2411

Q9UPU5
YFVIKPMDHCLLCVC

WDR64

201

B1ANS9
QYHVIRAATMCCLCQ

ZFHX3

1421

Q15911