Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	coumarin 7-hydroxylase activity	CYP2A6 CYP2A7 CYP2A13	1.87e-08	3	54	3	GO:0008389
GeneOntologyMolecularFunction	alpha-glucoside transmembrane transporter activity	SLC5A1 SLC5A2	7.18e-06	2	54	2	GO:0015151
GeneOntologyMolecularFunction	glucoside transmembrane transporter activity	SLC5A1 SLC5A2	2.15e-05	3	54	2	GO:0042947
GeneOntologyMolecularFunction	arachidonate epoxygenase activity	CYP2A6 CYP2A7 CYP2A13	3.63e-05	24	54	3	GO:0008392
GeneOntologyMolecularFunction	arachidonate monooxygenase activity	CYP2A6 CYP2A7 CYP2A13	5.22e-05	27	54	3	GO:0008391
GeneOntologyMolecularFunction	steroid hydroxylase activity	CYP2A6 CYP2A7 CYP2A13	1.05e-04	34	54	3	GO:0008395
GeneOntologyMolecularFunction	aromatase activity	CYP2A6 CYP2A7 CYP2A13	1.15e-04	35	54	3	GO:0070330
GeneOntologyMolecularFunction	D-glucose:sodium symporter activity	SLC5A1 SLC5A2	1.49e-04	7	54	2	GO:0005412
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP2A6 CYP2A7 CYP2A13	3.15e-04	49	54	3	GO:0016712
GeneOntologyMolecularFunction	carbohydrate:monoatomic cation symporter activity	SLC5A1 SLC5A2	9.51e-04	17	54	2	GO:0005402
GeneOntologyMolecularFunction	D-glucose transmembrane transporter activity	SLC5A1 SLC5A2	2.07e-03	25	54	2	GO:0055056
GeneOntologyMolecularFunction	hexose transmembrane transporter activity	SLC5A1 SLC5A2	2.07e-03	25	54	2	GO:0015149
GeneOntologyBiologicalProcess	phenylpropanoid metabolic process	CYP2A6 CYP2A7 CYP2A13	2.01e-06	10	54	3	GO:0009698
GeneOntologyBiologicalProcess	coumarin metabolic process	CYP2A6 CYP2A7 CYP2A13	2.01e-06	10	54	3	GO:0009804
GeneOntologyBiologicalProcess	alpha-glucoside transport	SLC5A1 SLC5A2	6.73e-06	2	54	2	GO:0000017
GeneOntologyBiologicalProcess	glucoside transport	SLC5A1 SLC5A2	2.01e-05	3	54	2	GO:0042946
GeneOntologyBiologicalProcess	epoxygenase P450 pathway	CYP2A6 CYP2A7 CYP2A13	2.52e-05	22	54	3	GO:0019373
GeneOntologyBiologicalProcess	renal D-glucose absorption	SLC5A1 SLC5A2	4.02e-05	4	54	2	GO:0035623
GeneOntologyBiologicalProcess	D-glucose import across plasma membrane	SLC5A1 SLC5A2	6.69e-05	5	54	2	GO:0098708
GeneOntologyBiologicalProcess	glycoside transport	SLC5A1 SLC5A2	6.69e-05	5	54	2	GO:1901656
GeneOntologyBiologicalProcess	carbohydrate import across plasma membrane	SLC5A1 SLC5A2	1.00e-04	6	54	2	GO:0098704
GeneOntologyBiologicalProcess	hexose import across plasma membrane	SLC5A1 SLC5A2	1.00e-04	6	54	2	GO:0140271
GeneOntologyBiologicalProcess	long-chain fatty acid metabolic process	CYP2A6 CYP2A7 CYP2A13 SLC27A6	3.12e-04	124	54	4	GO:0001676
MousePheno	abnormal bile salt homeostasis	CYP2A6 CYP2A7 CYP2A13 KMT2D	1.14e-05	47	42	4	MP:0005365
MousePheno	decreased intestinal cholesterol absorption	CYP2A6 CYP2A7 CYP2A13	1.67e-05	17	42	3	MP:0002647
MousePheno	abnormal intestinal cholesterol absorption	CYP2A6 CYP2A7 CYP2A13	2.36e-05	19	42	3	MP:0002645
MousePheno	abnormal renal glucose reabsorption	SLC5A1 SLC5A2	5.27e-05	4	42	2	MP:0011447
MousePheno	abnormal intestinal lipid absorption	CYP2A6 CYP2A7 CYP2A13	1.07e-04	31	42	3	MP:0005342
Domain	Cyt_P450_E_grp-I_CYP2A-like	CYP2A6 CYP2A7 CYP2A13	8.13e-08	4	52	3	IPR008067
Domain	CUB	NETO2 TLL2 CUZD1 OVCH1	1.03e-05	49	52	4	PF00431
Domain	CUB	NETO2 TLL2 CUZD1 OVCH1	1.12e-05	50	52	4	SM00042
Domain	-	NETO2 TLL2 CUZD1 OVCH1	1.31e-05	52	52	4	2.60.120.290
Domain	CUB	NETO2 TLL2 CUZD1 OVCH1	1.41e-05	53	52	4	PS01180
Domain	CUB_dom	NETO2 TLL2 CUZD1 OVCH1	1.89e-05	57	52	4	IPR000859
Domain	Homeobox_Pitx/unc30	PITX1 PITX2	2.28e-05	3	52	2	IPR016233
Domain	Peptidase_M12A	MEP1A TLL2	1.13e-04	6	52	2	IPR001506
Domain	Astacin	MEP1A TLL2	1.13e-04	6	52	2	PF01400
Domain	Na/solute_symporter_CS	SLC5A1 SLC5A2	2.11e-04	8	52	2	IPR018212
Domain	Cyt_P450_E_grp-I	CYP2A6 CYP2A7 CYP2A13	2.66e-04	45	52	3	IPR002401
Domain	NA_SOLUT_SYMP_1	SLC5A1 SLC5A2	4.11e-04	11	52	2	PS00456
Domain	Cyt_P450_CS	CYP2A6 CYP2A7 CYP2A13	4.32e-04	53	52	3	IPR017972
Domain	NA_SOLUT_SYMP_2	SLC5A1 SLC5A2	4.93e-04	12	52	2	PS00457
Domain	SSF	SLC5A1 SLC5A2	4.93e-04	12	52	2	PF00474
Domain	Na/solute_symporter	SLC5A1 SLC5A2	4.93e-04	12	52	2	IPR001734
Domain	NA_SOLUT_SYMP_3	SLC5A1 SLC5A2	4.93e-04	12	52	2	PS50283
Domain	CYTOCHROME_P450	CYP2A6 CYP2A7 CYP2A13	5.36e-04	57	52	3	PS00086
Domain	-	CYP2A6 CYP2A7 CYP2A13	5.64e-04	58	52	3	1.10.630.10
Domain	p450	CYP2A6 CYP2A7 CYP2A13	5.64e-04	58	52	3	PF00067
Domain	Cyt_P450	CYP2A6 CYP2A7 CYP2A13	6.23e-04	60	52	3	IPR001128
Domain	OAR	PITX1 PITX2	7.80e-04	15	52	2	PF03826
Domain	OAR	PITX1 PITX2	8.90e-04	16	52	2	PS50803
Domain	OAR_dom	PITX1 PITX2	8.90e-04	16	52	2	IPR003654
Domain	IQ	MYH8 SCN3A MYO16	1.49e-03	81	52	3	SM00015
Domain	Homeobox_CS	HOXB8 PITX1 PITX2 CUX1	1.78e-03	186	52	4	IPR017970
Domain	IQ_motif_EF-hand-BS	MYH8 SCN3A MYO16	2.02e-03	90	52	3	IPR000048
Domain	IQ	MYH8 SCN3A MYO16	2.21e-03	93	52	3	PS50096
Domain	EGF_Ca-bd_CS	EYS FAT3 TLL2	2.50e-03	97	52	3	IPR018097
Domain	EGF_CA	EYS FAT3 TLL2	2.64e-03	99	52	3	PS01187
Domain	ZnMc	MEP1A TLL2	2.94e-03	29	52	2	SM00235
Domain	Peptidase_Metallo	MEP1A TLL2	2.94e-03	29	52	2	IPR006026
Domain	EGF-type_Asp/Asn_hydroxyl_site	EYS FAT3 TLL2	3.21e-03	106	52	3	IPR000152
Domain	Homeobox	HOXB8 PITX1 PITX2 CUX1	4.06e-03	234	52	4	PF00046
Domain	EGF_3	MEP1A EYS FAT3 TLL2	4.12e-03	235	52	4	PS50026
Domain	EGF	MEP1A EYS FAT3 TLL2	4.12e-03	235	52	4	SM00181
Domain	HOMEOBOX_1	HOXB8 PITX1 PITX2 CUX1	4.18e-03	236	52	4	PS00027
Domain	HOX	HOXB8 PITX1 PITX2 CUX1	4.25e-03	237	52	4	SM00389
Domain	HOMEOBOX_2	HOXB8 PITX1 PITX2 CUX1	4.38e-03	239	52	4	PS50071
Domain	Homeobox_dom	HOXB8 PITX1 PITX2 CUX1	4.38e-03	239	52	4	IPR001356
Domain	EGF_CA	EYS FAT3 TLL2	4.76e-03	122	52	3	SM00179
Domain	EGF-like_Ca-bd_dom	EYS FAT3 TLL2	4.98e-03	124	52	3	IPR001881
Domain	Myosin_head_motor_dom	MYH8 MYO16	5.01e-03	38	52	2	IPR001609
Domain	MYOSIN_MOTOR	MYH8 MYO16	5.01e-03	38	52	2	PS51456
Domain	LAM_G_DOMAIN	EYS FAT3	5.01e-03	38	52	2	PS50025
Domain	Myosin_head	MYH8 MYO16	5.01e-03	38	52	2	PF00063
Domain	MYSc	MYH8 MYO16	5.01e-03	38	52	2	SM00242
Domain	EGF-like_dom	MEP1A EYS FAT3 TLL2	5.06e-03	249	52	4	IPR000742
Domain	EGF	MEP1A EYS TLL2	5.21e-03	126	52	3	PF00008
Domain	EGF_1	MEP1A EYS FAT3 TLL2	5.50e-03	255	52	4	PS00022
Domain	Laminin_G_2	EYS FAT3	5.54e-03	40	52	2	PF02210
Domain	EGF-like_CS	MEP1A EYS FAT3 TLL2	5.96e-03	261	52	4	IPR013032
Domain	EGF_2	MEP1A EYS FAT3 TLL2	6.29e-03	265	52	4	PS01186
Domain	LamG	EYS FAT3	6.67e-03	44	52	2	SM00282
Domain	-	HOXB8 PITX1 PITX2 CUX1	7.90e-03	283	52	4	1.10.10.60
Pathway	REACTOME_CYP2E1_REACTIONS	CYP2A6 CYP2A7 CYP2A13	2.94e-06	11	38	3	M27130
Pathway	REACTOME_CYP2E1_REACTIONS	CYP2A6 CYP2A7 CYP2A13	3.91e-06	12	38	3	MM14847
Pathway	REACTOME_FATTY_ACIDS	CYP2A6 CYP2A7 CYP2A13	1.43e-05	18	38	3	MM14841
Pathway	REACTOME_XENOBIOTICS	CYP2A6 CYP2A7 CYP2A13	3.08e-05	23	38	3	M5372
Pathway	REACTOME_XENOBIOTICS	CYP2A6 CYP2A7 CYP2A13	3.99e-05	25	38	3	MM14846
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_TO_DNA_ADDUCTS	CYP2A6 CYP2A13	7.04e-05	5	38	2	M47808
Pathway	KEGG_DRUG_METABOLISM_OTHER_ENZYMES	CYP2A6 CYP2A7 CYP2A13	3.44e-04	51	38	3	M17726
Pathway	WP_OXIDATION_BY_CYTOCHROME_P450	CYP2A6 CYP2A7 CYP2A13	6.12e-04	62	38	3	M39653
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP2A6 CYP2A7 CYP2A13	6.72e-04	64	38	3	M5650
Pathway	KEGG_RETINOL_METABOLISM	CYP2A6 CYP2A7 CYP2A13	6.72e-04	64	38	3	M9488
Pathway	REACTOME_FATTY_ACIDS	CYP2A7 CYP2A13	7.27e-04	15	38	2	M27126
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP2A6 CYP2A7 CYP2A13	7.36e-04	66	38	3	MM14839
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	CYP2A6 CYP2A7 CYP2A13	9.48e-04	72	38	3	M9257
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC5A1 SLC5A2	1.18e-03	19	38	2	MM14718
Pathway	REACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS	RANBP2 ABCA3 SLC5A1 SLC5A2	1.27e-03	177	38	4	M27476
Pathway	REACTOME_CELLULAR_HEXOSE_TRANSPORT	SLC5A1 SLC5A2	1.44e-03	21	38	2	M27058
Pubmed	Cerium-induced strain-dependent increase in Cyp2a-4/5 (cytochrome P4502a-4/5) expression in the liver and kidneys of inbred mice.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	1417950
Pubmed	Regulation of bile acid metabolism in mouse models with hydrophobic bile acid composition.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	31645370
Pubmed	Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	24045421
Pubmed	Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	32987105
Pubmed	Reciprocal regulation of sex-dependent expression of testosterone 15 alpha-hydroxylase (P-450(15 alpha)) in liver and kidney of male mice by androgen. Evidence for a single gene.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	3346244
Pubmed	Alteration of the substrate specificity of mouse 2A P450s by the identity of residue-209: steroid-binding site and orientation.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	22217847
Pubmed	Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	2765478
Pubmed	Sexual dimorphism of testosterone 15 alpha-hydroxylase mRNA levels in mouse liver. cDNA cloning and regulation.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	2415518
Pubmed	Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	2733794
Pubmed	A trans-acting locus regulates transcriptional repression of the female-specific steroid 15 alpha-hydroxylase gene in male mice.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	8297477
Pubmed	Differential distribution of CYP2A6 and CYP2A13 in the human respiratory tract.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	22890016
Pubmed	Lack of the steroid 15 alpha-hydroxylase gene (Cyp2a-4) in wild mouse strain Mus spretus: rapid evolution of the P450 gene superfamily.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	8188299
Pubmed	Site-directed mutagenesis of mouse steroid 7 alpha-hydroxylase (cytochrome P-450(7) alpha): role of residue-209 in determining steroid-cytochrome P-450 interaction.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	8484736
Pubmed	Comparison of hamster and mouse reveals interspecies differences in the regulation of hepatic CYP2A isozymes.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	8250953
Pubmed	The structure and characterization of type I P-450(15) alpha gene as major steroid 15 alpha-hydroxylase and its comparison with type II P-450(15) alpha gene.	CYP2A6 CYP2A7 CYP2A13	3.95e-09	3	56	3	2703500
Pubmed	Transcriptional regulation by HNF-4 of the steroid 15alpha-hydroxylase P450 (Cyp2a-4) gene in mouse liver.	CYP2A6 CYP2A7 CYP2A13	1.58e-08	4	56	3	9408084
Pubmed	A DNA methylation site in the male-specific P450 (Cyp 2d-9) promoter and binding of the heteromeric transcription factor GABP.	CYP2A6 CYP2A7 CYP2A13	1.58e-08	4	56	3	7565685
Pubmed	Circadian expression of the steroid 15 alpha-hydroxylase (Cyp2a4) and coumarin 7-hydroxylase (Cyp2a5) genes in mouse liver is regulated by the PAR leucine zipper transcription factor DBP.	CYP2A6 CYP2A7 CYP2A13	1.58e-08	4	56	3	10490589
Pubmed	Two steroid 15 alpha-hydroxylase genes and a homologous gene family in mice.	CYP2A6 CYP2A7 CYP2A13	1.58e-08	4	56	3	1970547
Pubmed	A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.	CYP2A6 CYP2A7 CYP2A13	7.88e-08	6	56	3	7668294
Pubmed	Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19.	CYP2A6 CYP2A7 CYP2A13	7.88e-08	6	56	3	8587134
Pubmed	Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses.	CYP2A6 CYP2A7 CYP2A13	1.38e-07	7	56	3	9630227
Pubmed	Organization and evolution of the Cyp2 gene cluster on mouse chromosome 7, and comparison with the syntenic human cluster.	CYP2A6 CYP2A7 CYP2A13	1.38e-07	7	56	3	14630516
Pubmed	Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder.	CYP2A6 CYP2A7 CYP2A13	3.30e-07	9	56	3	37838304
Pubmed	Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism.	CYP2A6 CYP2A7 CYP2A13	1.77e-06	15	56	3	29968852
Pubmed	Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.	MYH8 PITX1 PITX2 CUX1	2.23e-06	57	56	4	21122108
Pubmed	Expression of CYP2A genes in human liver and extrahepatic tissues.	CYP2A7 CYP2A13	2.55e-06	2	56	2	10353262
Pubmed	Expression and alternative splicing of the cytochrome P-450 CYP2A7.	CYP2A6 CYP2A7	2.55e-06	2	56	2	7864805
Pubmed	Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver.	CYP2A6 CYP2A13	2.55e-06	2	56	2	28298240
Pubmed	Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.	SLC5A1 SLC5A2	2.55e-06	2	56	2	24226519
Pubmed	Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2".	SLC5A1 SLC5A2	2.55e-06	2	56	2	21048164
Pubmed	Genetic polymorphisms for a phenobarbital-inducible cytochrome P-450 map to the Coh locus in mice.	CYP2A6 CYP2A13	2.55e-06	2	56	2	6309775
Pubmed	Characterization of a novel CYP2A7/CYP2A6 hybrid allele (CYP2A6*12) that causes reduced CYP2A6 activity.	CYP2A6 CYP2A7	2.55e-06	2	56	2	12325023
Pubmed	Mechanism-based inhibition of cytochrome P450 (CYP)2A6 by chalepensin in recombinant systems, in human liver microsomes and in mice in vivo.	CYP2A6 CYP2A13	2.55e-06	2	56	2	21418183
Pubmed	Evaluation of inhibition selectivity for human cytochrome P450 2A enzymes.	CYP2A6 CYP2A13	2.55e-06	2	56	2	22696418
Pubmed	Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.	CYP2A6 CYP2A13	2.55e-06	2	56	2	22262919
Pubmed	Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice.	CYP2A6 CYP2A13	2.55e-06	2	56	2	30876690
Pubmed	CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis.	CYP2A6 CYP2A13	2.55e-06	2	56	2	21395539
Pubmed	Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.	SLC5A1 SLC5A2	2.55e-06	2	56	2	20980548
Pubmed	Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.	CYP2A6 CYP2A13	2.55e-06	2	56	2	25635819
Pubmed	Thioglycosides as inhibitors of hSGLT1 and hSGLT2: potential therapeutic agents for the control of hyperglycemia in diabetes.	SLC5A1 SLC5A2	2.55e-06	2	56	2	17505558
Pubmed	Otlx2, an Otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain.	PITX1 PITX2	2.55e-06	2	56	2	9026314
Pubmed	Species differences in coumarin metabolism: a molecular modelling evaluation of CYP2A interactions.	CYP2A6 CYP2A13	2.55e-06	2	56	2	12162851
Pubmed	H2AFY promoter deletion causes PITX1 endoactivation and Liebenberg syndrome.	PITX1 MACROH2A1	2.55e-06	2	56	2	30711920
Pubmed	Molecular characterization of the murine Coh locus: an amino acid difference at position 117 confers high and low coumarin 7-hydroxylase activity in P450coh.	CYP2A6 CYP2A13	2.55e-06	2	56	2	1302041
Pubmed	Structural alteration of mouse P450coh by mutation of glycine-207 to proline: spin equilibrium, enzyme kinetics, and heat sensitivity.	CYP2A6 CYP2A13	2.55e-06	2	56	2	8395817
Pubmed	Sodium-glucose co-transporter (SGLT)2 and SGLT1 renal expression in patients with type 2 diabetes.	SLC5A1 SLC5A2	2.55e-06	2	56	2	28419670
Pubmed	Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice.	CYP2A6 CYP2A13	2.55e-06	2	56	2	25804444
Pubmed	Genetic variation between mice in their metabolism of coumarin and its derivatives.	CYP2A6 CYP2A13	2.55e-06	2	56	2	566237
Pubmed	Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression.	CYP2A6 CYP2A13	2.55e-06	2	56	2	1520280
Pubmed	Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model.	CYP2A6 CYP2A13	2.55e-06	2	56	2	19923441
Pubmed	Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model.	CYP2A6 CYP2A13	2.55e-06	2	56	2	23917075
Pubmed	Effects of lipopolysaccharide-stimulated inflammation and pyrazole-mediated hepatocellular injury on mouse hepatic Cyp2a5 expression.	CYP2A6 CYP2A13	2.55e-06	2	56	2	12499123
Pubmed	Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5.	CYP2A6 CYP2A13	2.55e-06	2	56	2	30222954
Pubmed	CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele.	CYP2A6 CYP2A7	2.55e-06	2	56	2	16636685
Pubmed	Identification and characterization of a 44 kDa protein that binds specifically to the 3'-untranslated region of CYP2a5 mRNA: inducibility, subcellular distribution and possible role in mRNA stabilization.	CYP2A6 CYP2A13	2.55e-06	2	56	2	8611142
Pubmed	Up-regulation of CYP2A5 expression by porphyrinogenic agents in mouse liver.	CYP2A6 CYP2A13	2.55e-06	2	56	2	7543189
Pubmed	Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype.	CYP2A6 CYP2A13	2.55e-06	2	56	2	27902773
Pubmed	Function and regulation of the Cyp2a5/CYP2A6 genes in response to toxic insults in the liver.	CYP2A6 CYP2A13	2.55e-06	2	56	2	22497566
Pubmed	Characterization and regulation of sex-specific mouse steroid hydroxylase genes.	CYP2A6 CYP2A13	2.55e-06	2	56	2	2372744
Pubmed	Coumarin toxicity in different strains of mice.	CYP2A6 CYP2A13	2.55e-06	2	56	2	665441
Pubmed	The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes.	CYP2A6 CYP2A7	2.55e-06	2	56	2	2322567
Pubmed	Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach.	CYP2A6 CYP2A13	2.55e-06	2	56	2	21473878
Pubmed	Renal SGLT mRNA expression in human health and disease: a study in two cohorts.	SLC5A1 SLC5A2	2.55e-06	2	56	2	31545924
Pubmed	Essential role of the cytochrome P450 enzyme CYP2A5 in olfactory mucosal toxicity of naphthalene.	CYP2A6 CYP2A13	2.55e-06	2	56	2	24104196
Pubmed	Pitx genes during cardiovascular development.	PITX1 PITX2	2.55e-06	2	56	2	12858527
Pubmed	The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis.	CYP2A6 CYP2A13	2.55e-06	2	56	2	7581481
Pubmed	The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference.	CYP2A6 CYP2A13	2.55e-06	2	56	2	26363552
Pubmed	Expression of the members of the Ptx family of transcription factors in human pituitary adenomas.	PITX1 PITX2	2.55e-06	2	56	2	10372733
Pubmed	Circadian Regulation of Hepatic Cytochrome P450 2a5 by Peroxisome Proliferator-Activated Receptor γ.	CYP2A6 CYP2A13	2.55e-06	2	56	2	30154104
Pubmed	Mouse liver P450Coh: genetic regulation of the pyrazole-inducible enzyme and comparison with other P450 isoenzymes.	CYP2A6 CYP2A13	2.55e-06	2	56	2	2712571
Pubmed	Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.	CYP2A6 CYP2A7 CYP2A13	2.65e-06	17	56	3	27197076
Pubmed	Molecular genetics of the human cytochrome P450 monooxygenase superfamily.	CYP2A6 CYP2A7 CYP2A13	4.42e-06	20	56	3	9890157
Pubmed	Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).	SLC27A6 SLC5A1 SLC5A2	5.96e-06	22	56	3	20965718
Pubmed	Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes.	CYP2A6 CYP2A13	7.63e-06	3	56	2	18602936
Pubmed	Paired-like homeodomain transcription factors 1 and 2 regulate follicle-stimulating hormone beta-subunit transcription through a conserved cis-element.	PITX1 PITX2	7.63e-06	3	56	2	18339718
Pubmed	Expression of cytochrome P450 2A5 in a glucose-6-phosphate dehydrogenase-deficient mouse model of oxidative stress.	CYP2A6 CYP2A13	7.63e-06	3	56	2	18068688
Pubmed	The bicoid-related Pitx gene family in development.	PITX1 PITX2	7.63e-06	3	56	2	9922405
Pubmed	CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism.	CYP2A6 CYP2A7	7.63e-06	3	56	2	11960914
Pubmed	Rip locus: regulation of female-specific isozyme (I-P-450(16 alpha) of testosterone 16 alpha-hydroxylase in mouse liver, chromosome localization, and cloning of P-450 cDNA.	CYP2A6 CYP2A13	7.63e-06	3	56	2	3219345
Pubmed	Sodium-glucose co-transporter (SGLT) and glucose transporter (GLUT) expression in the kidney of type 2 diabetic subjects.	SLC5A1 SLC5A2	7.63e-06	3	56	2	28477418
Pubmed	Close linkage of the cytochrome P450IIA gene subfamily (Cyp2a) to Cyp2b and Coh on mouse chromosome 7.	CYP2A6 CYP2A13	7.63e-06	3	56	2	1973143
Pubmed	Zfp30, a KRAB domain containing zinc finger protein gene, maps to mouse chromosome 7.	CYP2A6 CYP2A13	7.63e-06	3	56	2	7849402
Pubmed	Pitx factors are involved in basal and hormone-regulated activity of the human prolactin promoter.	PITX1 PITX2	7.63e-06	3	56	2	12223489
Pubmed	A novel defensive mechanism against acetaminophen toxicity in the mouse lateral nasal gland: role of CYP2A5-mediated regulation of testosterone homeostasis and salivary androgen-binding protein expression.	CYP2A6 CYP2A13	7.63e-06	3	56	2	21252290
Pubmed	Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.	SLC5A1 SLC5A2	7.63e-06	3	56	2	11749115
Pubmed	Mitochondrial targeting of bilirubin regulatory enzymes: An adaptive response to oxidative stress.	CYP2A6 CYP2A13	7.63e-06	3	56	2	25478736
Pubmed	Mechanisms of olfactory toxicity of the herbicide 2,6-dichlorobenzonitrile: essential roles of CYP2A5 and target-tissue metabolic activation.	CYP2A6 CYP2A13	7.63e-06	3	56	2	20840855
Pubmed	Improved glycemic control in mice lacking Sglt1 and Sglt2.	SLC5A1 SLC5A2	7.63e-06	3	56	2	23149623
Pubmed	Aryl hydrocarbon receptor nuclear translocator and upstream stimulatory factor regulate Cytochrome P450 2a5 transcription through a common E-box site.	CYP2A6 CYP2A13	7.63e-06	3	56	2	17466327
Pubmed	Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway.	CYP2A6 CYP2A13	7.63e-06	3	56	2	22552773
Pubmed	CYP2A7 pseudogene transcript affects CYP2A6 expression in human liver by acting as a decoy for miR-126.	CYP2A6 CYP2A7	7.63e-06	3	56	2	25710939
Pubmed	Antibodies to a renal Na+/glucose cotransport system localize to the apical plasma membrane domain of polar mouse embryo blastomeres.	SLC5A1 SLC5A2	7.63e-06	3	56	2	1702069
Pubmed	High-fat diet induces fibrosis in mice lacking CYP2A5 and PPARα: a new model for steatohepatitis-associated fibrosis.	CYP2A6 CYP2A13	7.63e-06	3	56	2	32877213
Pubmed	Limited heme synthesis in porphobilinogen deaminase-deficient mice impairs transcriptional activation of specific cytochrome P450 genes by phenobarbital.	CYP2A6 CYP2A13	7.63e-06	3	56	2	11106424
Pubmed	Experimental nonalcoholic fatty liver disease in mice leads to cytochrome p450 2a5 upregulation through nuclear factor erythroid 2-like 2 translocation.	CYP2A6 CYP2A13	7.63e-06	3	56	2	24191237
Pubmed	Regulation of CYP2A5 gene by the transcription factor nuclear factor (erythroid-derived 2)-like 2.	CYP2A6 CYP2A13	7.63e-06	3	56	2	17303623
Pubmed	Generation and characterization of a novel Cyp2a(4/5)bgs-null mouse model.	CYP2A6 CYP2A13	7.63e-06	3	56	2	23073733
Pubmed	Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2.	SLC5A1 SLC5A2	7.63e-06	3	56	2	30132032
Pubmed	PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism.	PITX1 PITX2	7.63e-06	3	56	2	21964592
Interaction	CYP2A7 interactions	CYP2A6 CYP2A7 CYP2A13	1.72e-08	3	53	3	int:CYP2A7
Cytoband	9q33.2	ZBTB6 OR1L4	1.05e-03	39	56	2	9q33.2
Cytoband	19q13.2	CYP2A6 CYP2A7 CYP2A13	1.08e-03	164	56	3	19q13.2
Cytoband	5q31.1	PITX1 MACROH2A1	2.72e-03	63	56	2	5q31.1
GeneFamily	Cytochrome P450 family 2	CYP2A6 CYP2A7 CYP2A13	7.78e-05	35	43	3	1001
GeneFamily	Bone morphogenetic proteins\|Astacins	MEP1A TLL2	8.24e-05	6	43	2	894
Coexpression	WENG_POR_DOSAGE	CYP2A6 CYP2A7 CYP2A13 ANXA5	4.57e-07	30	55	4	MM1199
Coexpression	WENG_POR_TARGETS_LIVER_UP	CYP2A6 CYP2A7 CYP2A13 ANXA5	4.71e-06	53	55	4	MM1203
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	KIF21B ZBTB6 KALRN NETO2 FAT3 SCN3A PLXNA4 DAPK1	2.80e-05	584	55	8	M39068
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#4_top-relative-expression-ranked_200	SLCO5A1 SCN3A CUX1	9.19e-06	17	52	3	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000	SLCO5A1 FAT3 SCN3A VAT1L CUX1	3.38e-05	151	52	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k2
CoexpressionAtlas	kidney_P0_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_100	HOXB8 FAT3	3.52e-05	4	52	2	gudmap_kidney_P0_CapMes_Crym_k2_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_top-relative-expression-ranked_200	SLCO5A1 SCN3A PITX2 VAT1L CUX1	5.78e-05	169	52	5	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_200
CoexpressionAtlas	kidney_e10.5_UretericTrunk_HoxB7_k-means-cluster#2_top-relative-expression-ranked_100	HOXB8 FAT3	5.85e-05	5	52	2	gudmap_kidney_e10.5_UretericTrunk_HoxB7_k2_100
CoexpressionAtlas	kidney_e10.5_UretericTip_HoxB7_k-means-cluster#4_top-relative-expression-ranked_100	HOXB8 FAT3	5.85e-05	5	52	2	gudmap_kidney_e10.5_UretericTip_HoxB7_k4_100
CoexpressionAtlas	DevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#1_top-relative-expression-ranked_200	MEP1A SLC5A1 SLC5A2	1.71e-04	44	52	3	gudmap_developingKidney_e15.5_early proxim tubul_200_k1
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Mucinous_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	MEP1A CYP2A6 CYP2A7 CYP2A13 DISP3	1.09e-06	145	56	5	1e52e3c615b49e7388cd58a04e74cafac9552447
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH8 ABCA3 NEXMIF DAPK1 MYO16	1.87e-06	162	56	5	06f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYH8 ABCA3 NEXMIF DAPK1 MYO16	1.87e-06	162	56	5	d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO5A1 ABCA3 SLC27A6 PCDHAC2 DAPK1	2.17e-06	167	56	5	8b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell	facs-Heart-LA-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B SLC27A6 P2RY10 SAMSN1 MYO16	2.24e-06	168	56	5	16c3313c4186fa327d71215f8eebc31fc12ff1c0
ToppCell	facs-Heart-LA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B SLC27A6 P2RY10 SAMSN1 MYO16	2.24e-06	168	56	5	24d1e0a05cda09ee3b80208d75cb2b601023f3bf
ToppCell	facs-Heart-LA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B SLC27A6 P2RY10 SAMSN1 MYO16	2.24e-06	168	56	5	b952af95a68888adedd03b1b60836d18524611ab
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASSF6 PLXNA4 DAPK1 MYO16 CUX1	4.09e-06	190	56	5	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS NETO2 TLL2 DAPK1 DENND2B	4.41e-06	193	56	5	658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KALRN FAT3 PLXNA4 DAPK1 CUX1	4.64e-06	195	56	5	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 MACROH2A1 SAMSN1	4.75e-06	196	56	5	782aa9e75ad032627d95dba763a37ae2b1f7f503
ToppCell	343B-Myeloid-Dendritic-cDC1\|343B / Donor, Lineage, Cell class and subclass (all cells)	SLCO5A1 NETO2 SCN3A P2RY10	3.61e-05	148	56	4	e44cdc1c3f3314c549a0afa9298c8568022b9d8b
ToppCell	343B-Myeloid-Dendritic-cDC1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SLCO5A1 NETO2 SCN3A P2RY10	4.22e-05	154	56	4	71d33b5dbfab5820e3daddb01806a69116ba8008
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF21B FAT3 P2RY10 SAMSN1	4.33e-05	155	56	4	c648512305166d2a2f0e284c127bc802af908071
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 SAMSN1 CUX1	4.90e-05	160	56	4	3b5a335786165391fe983ff0585cd508733793aa
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 SAMSN1 CUX1	4.90e-05	160	56	4	2586035a1380bc56814a6db0ca773ad835666042
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2A7 CYP2A13 FAT3 SLC5A1	5.65e-05	166	56	4	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2A7 CYP2A13 FAT3 SLC5A1	5.65e-05	166	56	4	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2A7 CYP2A13 FAT3 SLC5A1	5.65e-05	166	56	4	4586d6725403f879fc96f67be579022587ce1906
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	S100A11 ANXA5 MACROH2A1 SAMSN1	6.06e-05	169	56	4	c100a91be9b94bd433a3b172f4a1bfb9d2393003
ToppCell	facs-Heart-LV-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC27A6 POLI P2RY10 SAMSN1	6.20e-05	170	56	4	71e5e27c3c4e6cc8dc9b063bd51c21c049f54416
ToppCell	facs-Heart-LV-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC27A6 POLI P2RY10 SAMSN1	6.20e-05	170	56	4	255bbbd00d0e17510c5a8c5faa43ed90d887a9de
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	SLCO5A1 S100A11 P2RY10 SAMSN1	6.34e-05	171	56	4	7b0783d25055e5ea5b2fc44ebcb16bfd0adbcf81
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ABCA3 PLXNA4 DAPK1 SAMSN1	6.49e-05	172	56	4	c477008444d2d71071177807870d7455e90c2fad
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2A6 CYP2A7 CYP2A13 PCDHAC2	6.78e-05	174	56	4	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ABCA3 RASSF6 PITX1 SLC5A1	6.78e-05	174	56	4	aceca0a22bb1e380835e792681cfc9b752fb5496
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 CUZD1 MYO16 SLC5A1	6.94e-05	175	56	4	3f1b2e23fec953148fb0711e523c463adb07dca4
ToppCell	PBMC-Mild-cDC_11\|Mild / Compartment, Disease Groups and Clusters	SLCO5A1 NETO2 P2RY10 DENND2B	7.25e-05	177	56	4	974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXB8 MYH8 RASSF6 FAT3	7.41e-05	178	56	4	f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-basal_late\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CYP2A13 RASSF6 NEXMIF PITX1	7.41e-05	178	56	4	03f22485074b3cbf9a6ad4d543c5bbfa826dc741
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2A6 CYP2A7 DAPK1 VAT1L	7.41e-05	178	56	4	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH8 RASSF6 SCN3A DISP3	7.57e-05	179	56	4	f2e8fc975c30992611630197b79daaeef7c4211d
ToppCell	facs-Pancreas-Exocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 CUZD1 MYO16 SLC5A1	7.57e-05	179	56	4	bbfbfb32773346080127055b5aafa36bbf7d0942
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	RANBP2 NEXMIF PCDHAC2 TMX3	7.57e-05	179	56	4	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EYS PITRM1 SCN3A DISP3	7.57e-05	179	56	4	8ce5000088b727783a0619baa16a2cd036d21f54
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 NHSL2 ANXA5 DAPK1	7.90e-05	181	56	4	6771f2c72073c59aab905945a619907b7fd0fd77
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	CYP2A6 CYP2A7 DAPK1 VAT1L	7.90e-05	181	56	4	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN FAT3 DISP3 MYO16	8.42e-05	184	56	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN FAT3 DISP3 MYO16	8.42e-05	184	56	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN FAT3 DISP3 MYO16	8.42e-05	184	56	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	CYP2A6 CYP2A7 CYP2A13 VAT1L	8.60e-05	185	56	4	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MEP1A PITX1 SLC5A1 SLC5A2	8.78e-05	186	56	4	fa5f602f01de5beec529d9f5208172b2914a952d
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	S100A11 NHSL2 ANXA5 MACROH2A1	8.96e-05	187	56	4	cbe25fb3fc8ed6245dc767c884c298c89a774cce
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC27A6 FAT3 PLXNA4 MYO16	9.34e-05	189	56	4	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	S100A11 ANXA5 MACROH2A1 SAMSN1	9.53e-05	190	56	4	00ef6ec71353e42260c0d807d7da65b63154c288
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	S100A11 ANXA5 MACROH2A1 SAMSN1	9.53e-05	190	56	4	18c020ca9a23399214133ec255ab870e0060f2e1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 SAMSN1	9.53e-05	190	56	4	6cf9a41c1a0fa1ce6a8711caa7c71ff6b55df9e1
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLCO5A1 KALRN FAT3 MYO16	9.73e-05	191	56	4	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2A6 CYP2A7 DAPK1 VAT1L	9.73e-05	191	56	4	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYH8 ANXA5 PITX1 DENND2B	9.73e-05	191	56	4	89d03c4133dda852a3713c0902a7d67941cf5b21
ToppCell	18-Distal-Epithelial-Secretory_progenitor\|Distal / Age, Tissue, Lineage and Cell class	S100A11 CYP2A6 CYP2A7 CYP2A13	9.92e-05	192	56	4	9fae988ecd2ef1231bfd42a678a4903517694cbe
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXB8 KALRN RASSF6 DAPK1	9.92e-05	192	56	4	6fb56d062c35617b18b927704bf5fba894faed81
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RASSF6 DAPK1 MYO16 CUX1	9.92e-05	192	56	4	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS NETO2 TLL2 DENND2B	1.01e-04	193	56	4	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	S100A11 ABCA3 NEXMIF CUX1	1.01e-04	193	56	4	54506c0da2f219f472b95e8935a78b657a8dec41
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN FAT3 SCN3A PCDHAC2	1.01e-04	193	56	4	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN FAT3 SCN3A PCDHAC2	1.01e-04	193	56	4	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	CYP2A6 CYP2A7 NEXMIF VAT1L	1.01e-04	193	56	4	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	S100A11 ABCA3 NEXMIF CUX1	1.01e-04	193	56	4	2d42721fac1bee294ede47d609bebb3e7d36bf0c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NETO2 TLL2 DAPK1 DENND2B	1.01e-04	193	56	4	3ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLCO5A1 PLXNA4 VAT1L MYO16	1.01e-04	193	56	4	088c8b1e968f5356502347eaabdc6b1b1d4befd0
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	NETO2 PLXNA4 DISP3 CUX1	1.01e-04	193	56	4	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	healthy_donor-Myeloid-Monocytic-CD16+_Monocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	S100A11 ANXA5 DAPK1 CUX1	1.03e-04	194	56	4	ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS NETO2 DAPK1 DENND2B	1.03e-04	194	56	4	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 SAMSN1	1.03e-04	194	56	4	4f0fe237b326552dd1b018c58f0a26c365cfa6c5
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	S100A11 ANXA5 MACROH2A1 SAMSN1	1.03e-04	194	56	4	12e42433a7b7c17c46049ef450223daf2976a59a
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC27A6 FAT3 PLXNA4 MYO16	1.03e-04	194	56	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EYS NETO2 NHSL2 DAPK1	1.03e-04	194	56	4	1bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 SAMSN1	1.03e-04	194	56	4	935ec4554d740935d9d9a59d9d6b5293d1c27d1f
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KALRN FAT3 SCN3A PCDHAC2	1.05e-04	195	56	4	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2A6 CYP2A7 DAPK1 VAT1L	1.05e-04	195	56	4	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Control-Myeloid\|Control / Disease state, Lineage and Cell class	S100A11 ANXA5 MACROH2A1 SAMSN1	1.05e-04	195	56	4	46ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCell	367C-Lymphocytic-CD4_T-cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	S100A11 ANXA5 P2RY10 SAMSN1	1.05e-04	195	56	4	8b2e29f3b12fcc474abdf3707de96e4613ead1bc
ToppCell	10x5'-blood-Myeloid_Monocytic-Nonclassical_monocytes\|blood / Manually curated celltypes from each tissue	S100A11 ANXA5 DAPK1 CUX1	1.05e-04	195	56	4	88d65c7c3a28922c125bd9f7c403a55d7d4d83a9
ToppCell	distal-Epithelial-Proximal_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP2A13 RASSF6 PITX1 DISP3	1.07e-04	196	56	4	c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 MACROH2A1 SAMSN1	1.07e-04	196	56	4	efddf04f32fc01ab2c1dfb5a7ab0931f0fe86eff
ToppCell	BAL-Control-cDC_10\|Control / Compartment, Disease Groups and Clusters	SLCO5A1 RASSF6 P2RY10 SAMSN1	1.07e-04	196	56	4	c32b7b7e6a4781c19c30c6e32d5563f82355deb0
ToppCell	10x5'-lymph-node_spleen-Myeloid_Dendritic-DC2\|lymph-node_spleen / Manually curated celltypes from each tissue	S100A11 ANXA5 DAPK1 MACROH2A1	1.07e-04	196	56	4	9666b5380e2b2a3c3b56a8c769817a1df8820ed6
ToppCell	distal-Epithelial-Proximal_Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP2A13 RASSF6 PITX1 DISP3	1.07e-04	196	56	4	a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCell	Control-Myeloid-Macrophage\|Control / Disease state, Lineage and Cell class	S100A11 ANXA5 MACROH2A1 SAMSN1	1.07e-04	196	56	4	e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	NETO2 PLXNA4 DISP3 CUX1	1.07e-04	196	56	4	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	distal-3-Epithelial-Proximal_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP2A13 RASSF6 PITX1 DISP3	1.07e-04	196	56	4	7e1a565dd2da4f375cbce8842ba4fd6c22ac8375
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 MACROH2A1 SAMSN1	1.07e-04	196	56	4	5bcb57c57d5da0440220a1133a96aa89407bd871
ToppCell	10x5'-Liver-Myeloid_Monocytic-Nonclassical_monocytes\|Liver / Manually curated celltypes from each tissue	S100A11 ANXA5 DAPK1 CUX1	1.10e-04	197	56	4	b0b4a704e1137f48e2258df17285ed89684ae98d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 MACROH2A1 SAMSN1	1.10e-04	197	56	4	ad589eaf49921e128d5eb38173e4b0c4515abeec
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 MACROH2A1	1.10e-04	197	56	4	321ccd20b0bb03c99a00452ac3c637ee3aa73ecf
ToppCell	IPF-Myeloid-Macrophage\|IPF / Disease state, Lineage and Cell class	S100A11 ANXA5 MACROH2A1 SAMSN1	1.10e-04	197	56	4	a2ffb33c7cad6be43cbb8ed9a91338923cc07db4
ToppCell	10x5'-bone_marrow-Myeloid_Monocytic-Nonclassical_monocytes\|bone_marrow / Manually curated celltypes from each tissue	S100A11 ANXA5 DAPK1 CUX1	1.10e-04	197	56	4	dcf1e74b7c21466d38d68f44d404bce14ade2805
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Myeloid\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 MACROH2A1 SAMSN1	1.10e-04	197	56	4	59745f84346efdcb2ab864a84681f043ba4c9b86
ToppCell	distal-Epithelial-Basal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HOXB8 EYS PITX1 PITX2	1.10e-04	197	56	4	75b4292ce2ad7f9c8b6a4781e1cb71f5b18b74e3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLCO5A1 PLXNA4 DISP3 MIR9-1HG	1.12e-04	198	56	4	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 MACROH2A1	1.12e-04	198	56	4	4d70995b4dd6365b0c3cda3663a82efdb4870d19
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	SLCO5A1 PLXNA4 DISP3 MIR9-1HG	1.12e-04	198	56	4	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	nucseq-Immune-Immune_Myeloid\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	S100A11 ANXA5 MACROH2A1 SAMSN1	1.12e-04	198	56	4	d0ad9ef51dd9d0135931fa627144721ad9aa5397
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 DAPK1 MACROH2A1	1.12e-04	198	56	4	2a361af16bf6ecec12f22bdf7926afc7e5ad45ae
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CYP2A7 RASSF6 PITX1 PCDHAC2	1.12e-04	198	56	4	5dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	S100A11 ANXA5 MACROH2A1 SAMSN1	1.14e-04	199	56	4	571accef38f5b03a7e032495d5c6d25d27073428
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial-Club\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP2A6 CYP2A7 CYP2A13 SLC5A1	1.14e-04	199	56	4	2b17694cffbec28a2c8f165dfcff6bab94aa0f4c
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX-Club\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	CYP2A6 CYP2A7 CYP2A13 SLC5A1	1.14e-04	199	56	4	111cfd589ec6795075d8d88d7664bfb23eba5bf6
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SLCO5A1 P2RY10 DAPK1 SAMSN1	1.14e-04	199	56	4	7b3d4c62b11268c7c1599600d8a7b331287cf21a
Drug	2'-methoxyacetophenone	CYP2A6 CYP2A7 CYP2A13	1.33e-08	3	55	3	CID000068481
Drug	N-nitrosomethylaniline	CYP2A6 CYP2A7 CYP2A13	4.76e-06	14	55	3	CID000011957
Drug	nicotine imine	CYP2A6 CYP2A13	5.73e-06	2	55	2	ctd:C034629
Drug	propargyl ether	CYP2A6 CYP2A13	5.73e-06	2	55	2	ctd:C531209
Drug	alpha-nicotyrine	CYP2A6 CYP2A13	5.73e-06	2	55	2	ctd:C008615
Drug	benzylphenol	SLC5A1 SLC5A2	5.73e-06	2	55	2	CID000024216
Drug	Hempa	CYP2A6 CYP2A13	5.73e-06	2	55	2	ctd:D006492
Drug	beta-D-glucopyranosylphenyl isothiocyanate	SLC5A1 SLC5A2	5.73e-06	2	55	2	CID004182945
Drug	sergliflozin	SLC5A1 SLC5A2	5.73e-06	2	55	2	CID009824918
Drug	N-nitrosoguvacoline	CYP2A6 CYP2A13	5.73e-06	2	55	2	ctd:C036676
Drug	6-hydroxymelatonin	CYP2A6 CYP2A7 CYP2A13 DENND2B	6.46e-06	50	55	4	CID000001864
Drug	NSC35549	CYP2A6 CYP2A7 CYP2A13	1.99e-05	22	55	3	CID000411697
Drug	2,2,2-trichloroethanol	CYP2A6 CYP2A7 CYP2A13 SLC5A1	2.93e-05	73	55	4	CID000008259
Drug	7-hydroxycoumarin	CYP2A6 CYP2A7 CYP2A13 DENND2B	3.26e-05	75	55	4	CID005281426
Drug	Bd 3	ANXA5 CUX1	3.43e-05	4	55	2	CID000199015
Drug	NMPA	CYP2A6 CYP2A13	3.43e-05	4	55	2	CID000132101
Drug	N'-nitrosoanatabine	CYP2A6 CYP2A13	3.43e-05	4	55	2	ctd:C032978
Drug	C14845	CYP2A6 CYP2A7 CYP2A13	3.74e-05	27	55	3	CID011954064
Drug	BP-9,10-oxide	CYP2A6 CYP2A7 CYP2A13	3.74e-05	27	55	3	CID000037456
Drug	Brn 4136738	CYP2A6 CYP2A7 CYP2A13	3.74e-05	27	55	3	CID000050331
Drug	9-OH-BaP-4,5-oxide	CYP2A6 CYP2A7 CYP2A13	4.19e-05	28	55	3	CID000115064
Drug	11-H-14,15-EETA	CYP2A6 CYP2A7 CYP2A13	5.17e-05	30	55	3	CID011954058
Drug	19-hydroxytestosterone	CYP2A6 CYP2A7 CYP2A13	5.17e-05	30	55	3	CID000150968
Drug	diosmetin	CYP2A6 CYP2A7 CYP2A13 SLC5A1	5.34e-05	85	55	4	CID005281612
Drug	N-methyl-N-2-(methylsulfinyl)ethylpropionic acid amide	CYP2A6 CYP2A13	5.70e-05	5	55	2	ctd:C062567
Drug	benzyl selenocyanate	CYP2A6 CYP2A13	5.70e-05	5	55	2	ctd:C054108
Drug	BP-7,8-oxide	CYP2A6 CYP2A7 CYP2A13	6.30e-05	32	55	3	CID000037455
Drug	parathion	CYP2A6 CYP2A7 CYP2A13 VPS13A	6.97e-05	91	55	4	CID000000991
Drug	12(13)-EpOME	CYP2A6 CYP2A7 CYP2A13	7.57e-05	34	55	3	CID000001416
Drug	TCEO	CYP2A6 CYP2A7 CYP2A13	7.57e-05	34	55	3	CID000028167
Drug	AC1O5XSP	CYP2A6 CYP2A7 CYP2A13	7.57e-05	34	55	3	CID006442739
Drug	2-naphthol	CYP2A6 CYP2A7 CYP2A13 DENND2B	7.59e-05	93	55	4	CID000008663
Drug	AC1L1CJI	CYP2A6 CYP2A7 CYP2A13	8.26e-05	35	55	3	CID000001929
Drug	acenaphthene-1-ol	CYP2A6 CYP2A13	8.54e-05	6	55	2	ctd:C023723
Drug	lactisole	TAS1R2 SLC5A1	8.54e-05	6	55	2	ctd:C495512
Drug	AC1L196J	CYP2A6 CYP2A13	8.54e-05	6	55	2	CID000000415
Drug	menthofuran	CYP2A6 CYP2A13	8.54e-05	6	55	2	ctd:C054487
Drug	N'-nitrosoanabasine	CYP2A6 CYP2A13	8.54e-05	6	55	2	ctd:C010257
Drug	15-H-11,12-EETA	CYP2A6 CYP2A7 CYP2A13	9.00e-05	36	55	3	CID011954042
Drug	AC1L3NGJ	CYP2A6 CYP2A7 CYP2A13	9.00e-05	36	55	3	CID000092121
Drug	hexamethylphosphoramide	CYP2A6 CYP2A7 CYP2A13	9.00e-05	36	55	3	CID000012679
Drug	11,14,15-THET	CYP2A6 CYP2A7 CYP2A13	1.15e-04	39	55	3	CID006439531
Drug	tolbutamide	CYP2A6 CYP2A7 CYP2A13 SLC5A1 SLC5A2	1.16e-04	198	55	5	CID000005505
Drug	acenaphthene	CYP2A6 CYP2A13	1.19e-04	7	55	2	ctd:C042552
Drug	11,12,15-trihydroxyeicosatrienoic acid	CYP2A6 CYP2A7 CYP2A13	1.43e-04	42	55	3	CID006439610
Drug	diclofenac	CYP2A6 CYP2A7 CYP2A13 USP24 CUX1	1.49e-04	209	55	5	CID000003032
Drug	Organometallic Compounds	ANXA5 SLC5A1 SLC5A2	1.65e-04	44	55	3	ctd:D009942
Drug	polybrominated biphenyl	CYP2A6 CYP2A7 CYP2A13	1.65e-04	44	55	3	CID000042948
Drug	naphthalene-1,2-dihydrodiol	CYP2A6 CYP2A7 CYP2A13	1.76e-04	45	55	3	CID000000362
Drug	8-MOP	CYP2A6 CYP2A7 CYP2A13 ANXA5	1.91e-04	118	55	4	CID000004114
Drug	C14802	CYP2A6 CYP2A7 CYP2A13	2.01e-04	47	55	3	CID011954053
Drug	N-nitrosoguvacoline	CYP2A6 CYP2A13	2.04e-04	9	55	2	CID000062103
Drug	p-tolualdehyde	CYP2A6 POLI	2.04e-04	9	55	2	CID000007725
Drug	3-(methylnitrosamino)propionaldehyde	CYP2A6 CYP2A13	2.04e-04	9	55	2	CID000098533
Drug	acenaphthylene	CYP2A6 CYP2A13	2.04e-04	9	55	2	ctd:C042553
Drug	C14800	CYP2A6 CYP2A7 CYP2A13	2.14e-04	48	55	3	CID011954051
Drug	nitro-L	CYP2A6 CYP2A7 CYP2A13	2.14e-04	48	55	3	CID000006849
Drug	naphthalene	CYP2A6 CYP2A7 CYP2A13 SCN3A	2.24e-04	123	55	4	CID000000931
Drug	19-HETE	CYP2A6 CYP2A7 CYP2A13	2.27e-04	49	55	3	CID006439528
Drug	bromobenzene-3,4-oxide	CYP2A6 CYP2A7 CYP2A13	2.27e-04	49	55	3	CID000108121
Drug	bromobenzene-2,3-oxide	CYP2A6 CYP2A7 CYP2A13	2.41e-04	50	55	3	CID003036760
Drug	1,1-dichloroethylene epoxide	CYP2A6 CYP2A7 CYP2A13	2.41e-04	50	55	3	CID000119521
Drug	naphthalene epoxide	CYP2A6 CYP2A7 CYP2A13	2.56e-04	51	55	3	CID000108063
Drug	mepivacaine	CYP2A6 CYP2A7 CYP2A13	2.56e-04	51	55	3	CID000004062
Drug	9-hydroxybenzo(a)pyrene	CYP2A6 CYP2A7 CYP2A13	2.87e-04	53	55	3	CID000028598
Drug	dichloroacetaldehyde	CYP2A6 CYP2A7 CYP2A13	3.03e-04	54	55	3	CID000006576
Drug	D-702	CYP2A6 CYP2A13	3.11e-04	11	55	2	CID000054077
Drug	NSC-312017	POLI CUX1	3.11e-04	11	55	2	CID000432667
Drug	chloroacetyl chloride	CYP2A6 CYP2A7 CYP2A13	3.20e-04	55	55	3	CID000006577
Drug	1,2-dihydroxynaphthalene	CYP2A6 CYP2A7 CYP2A13	3.56e-04	57	55	3	CID000011318
Drug	coumarin	CYP2A6 CYP2A7 CYP2A13 DAPK1	3.56e-04	139	55	4	CID000000323
Drug	3-methyleneindolenine	CYP2A6 ANXA5	3.72e-04	12	55	2	CID000170404
Drug	bromoacetaldehyde	CYP2A6 CYP2A7 CYP2A13	3.75e-04	58	55	3	CID000105131
Drug	AbHT	CYP2A6 CYP2A13 ANXA5	4.14e-04	60	55	3	CID000002143
Drug	1,1-dichloroethylene	CYP2A6 CYP2A7 CYP2A13	4.14e-04	60	55	3	CID000006366
Drug	BP-4,5-oxide	CYP2A6 CYP2A7 CYP2A13	4.35e-04	61	55	3	CID000037786
Drug	Skatole	CYP2A6 CYP2A13	4.39e-04	13	55	2	ctd:D012862
Drug	d 6-20	CYP2A6 CYP2A13	4.39e-04	13	55	2	CID000161569
Drug	bromide	CYP2A6 CYP2A7 CYP2A13 ANXA5 VPS13A	4.60e-04	267	55	5	CID000000259
Drug	chlorzoxazone	CYP2A6 CYP2A7 CYP2A13	4.78e-04	63	55	3	CID000002733
Drug	MnPN	CYP2A6 CYP2A13	5.12e-04	14	55	2	CID000062163
Disease	Synostosis, Carpal, with Dysplastic Elbow Joints and Brachydactyly	PITX1 MACROH2A1	3.41e-06	2	55	2	C1861313
Disease	nicotine metabolite ratio	CYP2A6 CYP2A7	2.22e-04	12	55	2	EFO_0007794
Disease	acute graft vs. host disease, donor genotype effect measurement	EYS KALRN	3.53e-04	15	55	2	EFO_0004599, EFO_0007892
Disease	diet measurement, HOMA-B	FAT3 PLXNA4	5.72e-04	19	55	2	EFO_0004469, EFO_0008111
Disease	caffeine metabolite measurement	CYP2A6 CYP2A7	5.72e-04	19	55	2	EFO_0007872
Disease	lobe attachment	KIF21B CYP2A13 SLC27A6 CUX1	6.06e-04	207	55	4	EFO_0007667
Disease	Squamous cell carcinoma of esophagus	CYP2A6 KMT2D FAT3	7.51e-04	95	55	3	C0279626
Disease	unipolar depression, neuroticism measurement	EYS TLL2	9.17e-04	24	55	2	EFO_0003761, EFO_0007660
Disease	gas trapping measurement	KMT2D TAS1R2	1.34e-03	29	55	2	EFO_0007628

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSLTNTMGGYKESFS	DAPK1	1266	P53355
MAFESTTYKGKSSFQ	DISP3	1121	Q9P2K9
FTSTSTGQLYEMFSS	CYP2A6	211	P11509
SFYSKAMQEAGSTSM	CUX1	491	P39880
LKAISSYFVSTMSSS	MACROH2A1	331	O75367
STISFSFMVSTFFSK	ABCA3	356	Q99758
NFATSLYSMIKGDTS	ANXA5	291	P08758
TFSAMFINDTSSAKF	CCDC180	846	Q9P1Z9
VSEYSSETFSFMLTG	DENND2B	756	P78524
FSMSNQDLYGYSTSS	MIR9-1HG	116	Q13536
SFMFQGSSNTEFKST	RANBP2	1871	P49792
PFSSFTSMKSSDVFS	RASSF6	111	Q6ZTQ3
TKMSSLDTNTDFYIG	EYS	2831	Q5T1H1
NKTSFSTAKFMGNSY	EYS	2971	Q5T1H1
KESSTLNMGNLSFYT	NCBP2L	36	A6PVI3
SSMVSQLYFSSSGKL	MYO16	451	Q9Y6X6
AMKTLASLFSTYASA	MYH8	616	P13535
ETGMTFASTSFVFYN	PLXNA4	641	Q9HCM2
SEFSEGSFSQSFTMK	KIF21B	1111	O75037
NFGSSKFIFETSMVS	KALRN	141	O60229
MSSYFVNSLFSKYKT	HOXB8	1	P17481
SGSDTFMFYNTGAQT	PCDHAC2	801	Q9Y5I4
FTATSTGQLYEMFSS	CYP2A13	211	Q16696
FKSYLSKYQMSSFSN	CCDC18	411	Q5T9S5
FTSTSTGQLYEMFSS	CYP2A7	211	P20853
MDSGLHFTQSFYSTS	FAT3	1976	Q8TDW7
SSGFTNSAMQYSFVS	CCP110	741	O43303
GKYNTSMALFESNSF	CUZD1	391	Q86UP6
GFNSSSSSYMSSQKD	POLI	606	Q9UNA4
KYTETFKMGSNSTST	P2RY10	6	O00398
METKNYSSSTSGFIL	OR1L4	1	Q8NGR5
LANLSFIDTFYSSSM	OR4C3	61	Q8NH37
TKSFTFFNSMSPLSS	PITX1	196	P78337
STFSTSWKGDAFTYM	NHSL2	386	Q5HYW2
KASDSMDSLYSGQSS	SAMSN1	121	Q9NSI8
DSRSTFFDKKYSNMS	NEXMIF	1421	Q5QGS0
SIFSSSNMTVIYFKS	OVCH1	501	Q7RTY7
AGYFMQFSTSSGSAE	MEP1A	311	Q16819
LSTFMNAFTASDYTL	PITRM1	131	Q5JRX3
NMTFLFVSLSYTAES	SLCO5A1	431	Q9H2Y9
MKTFNSTFKKSSYTF	NETO2	471	Q8NC67
SASLSTKSFPFFNSM	PITX2	186	Q99697
NYTLSKTEFLSFMNT	S100A11	31	P31949
TTSYFNGTMDSNGTF	SCN3A	291	Q9NY46
KMDATSYSSIASEFG	TMX3	81	Q96JJ7
ISTLKMYTDGSTFSS	VPS13A	1436	Q96RL7
MYTDGSTFSSFSLKN	VPS13A	1441	Q96RL7
SIFNSSSTLFTMDIY	SLC5A2	396	P31639
ASGSSMFLRFYSDAS	TLL2	861	Q9Y6L7
GSSNMVTGETKSFFS	VAT1L	276	Q9HCJ6
FITLSMTFYFTSSVS	TAS1R2	761	Q8TE23
SGVFSSSYAMEQEKS	USP24	1056	Q9UPU5
GESDNFTFSFKMFTS	TMC2	371	Q8TDI7
YAATESSISFMNYTG	SLC27A6	361	Q9Y2P4
SIFNSASTLFTMDIY	SLC5A1	396	P13866
NSTFFSVSSSDLMSK	VPS4A	186	Q9UN37
SSKASMYFSETQHSL	ZBTB6	241	Q15916
NSTSMSKAYQSTFTG	KMT2D	5356	O14686