Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentchromosomal region

ZNF827 NSL1 PRKDC XPO1 RAD17 THOC6

4.84e-04421506GO:0098687
GeneOntologyCellularComponentannulate lamellae

EIF5AL1 XPO1

5.01e-0414502GO:0005642
GeneOntologyCellularComponentchromosome, telomeric region

ZNF827 PRKDC RAD17 THOC6

8.27e-04176504GO:0000781
DomainCopine

CPNE6 CPNE7

2.30e-049482PF07002
DomainCopine

CPNE6 CPNE7

2.30e-049482IPR010734
Domain-

CPNE6 PIK3CG ITSN1 CPNE7

5.62e-041484842.60.40.150
DomainPI3/4_kinase_CS

PIK3CG PRKDC

6.65e-0415482IPR018936
Domain-

PIK3CG PRKDC

7.58e-04164821.10.1070.11
DomainPI3Kc

PIK3CG PRKDC

7.58e-0416482SM00146
DomainC2_dom

CPNE6 PIK3CG ITSN1 CPNE7

8.25e-04164484IPR000008
DomainPI3/4_kinase_cat_dom

PIK3CG PRKDC

9.64e-0418482IPR000403
DomainPI3_PI4_kinase

PIK3CG PRKDC

9.64e-0418482PF00454
DomainPI3_4_KINASE_3

PIK3CG PRKDC

9.64e-0418482PS50290
DomainPI3_4_KINASE_1

PIK3CG PRKDC

9.64e-0418482PS00915
DomainPI3_4_KINASE_2

PIK3CG PRKDC

9.64e-0418482PS00916
DomainCT

GREM2 CCN6

1.45e-0322482SM00041
DomainPentatricopeptide_repeat

PRKDC XAB2

1.58e-0323482IPR002885
DomainCys_knot_C

GREM2 CCN6

1.87e-0325482IPR006207
DomainCTCK_2

GREM2 CCN6

1.87e-0325482PS01225
DomainETS_DOMAIN_1

ERF ELF1

2.34e-0328482PS00345
DomainETS_DOMAIN_2

ERF ELF1

2.34e-0328482PS00346
DomainETS

ERF ELF1

2.34e-0328482SM00413
DomainEts_dom

ERF ELF1

2.34e-0328482IPR000418
DomainETS_DOMAIN_3

ERF ELF1

2.34e-0328482PS50061
DomainEts

ERF ELF1

2.34e-0328482PF00178
DomainMyb_DNA-binding

MYSM1 MYBL1

3.65e-0335482PF00249
DomainPTPc

PTPN13 PTPRR

3.85e-0336482SM00194
DomainMYB_LIKE

MYSM1 MYBL1

4.29e-0338482PS50090
DomainTYR_PHOSPHATASE_PTP

PTPN13 PTPRR

4.51e-0339482PS50055
DomainC2

CPNE6 ITSN1 CPNE7

4.63e-03131483PF00168
DomainPTPase_domain

PTPN13 PTPRR

4.98e-0341482IPR000242
DomainY_phosphatase

PTPN13 PTPRR

4.98e-0341482PF00102
DomainC2

CPNE6 ITSN1 CPNE7

5.25e-03137483SM00239
DomainC2

CPNE6 ITSN1 CPNE7

5.80e-03142483PS50004
DomainAAA+_ATPase

ABCC4 DNAH6 RAD17

6.02e-03144483IPR003593
DomainAAA

ABCC4 DNAH6 RAD17

6.02e-03144483SM00382
DomainSANT

MYSM1 MYBL1

7.32e-0350482SM00717
DomainSANT/Myb

MYSM1 MYBL1

7.90e-0352482IPR001005
DomainHEAT

PRKDC XPO1

9.76e-0358482IPR000357
DomainPTPc_motif

PTPN13 PTPRR

1.01e-0259482SM00404
DomainTyr_Pase_cat

PTPN13 PTPRR

1.01e-0259482IPR003595
Pubmed

ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression.

ERF XPO1

2.11e-06251214729966
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SHLD2 SEPSECS PTPN13 NRDC PTPRR TEX2 ITSN1 TMEM131L HUWE1 RAD17

3.32e-061084511011544199
Pubmed

A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy.

ABCC4 DCBLD1

6.32e-06351223478653
Pubmed

HUWE1-dependent DNA-PKcs neddylation modulates its autophosphorylation in DNA damage response.

PRKDC HUWE1

6.32e-06351232457294
Pubmed

Subcellular localization of the hypusine-containing eukaryotic initiation factor 5A by immunofluorescent staining and green fluorescent protein tagging.

EIF5AL1 XPO1

6.32e-06351212210765
Pubmed

An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis.

CXCR6 PRKDC

1.26e-05451230220458
Pubmed

Phosphoinositide 3-kinaseγ controls the intracellular localization of CpG to limit DNA-PKcs-dependent IL-10 production in macrophages.

PIK3CG PRKDC

1.26e-05451222053215
Pubmed

PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro.

PIK3CG PRKDC

1.26e-05451218678286
Pubmed

Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.

NRDC PRKDC XPO1 HUWE1 THOC6

1.31e-0520651522174317
Pubmed

Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.

PIK3CG PRKDC

2.10e-05551215664519
Pubmed

Copines-1, -2, -3, -6 and -7 show different calcium-dependent intracellular membrane translocation and targeting.

CPNE6 CPNE7

2.10e-05551221087455
Pubmed

The functional interactome landscape of the human histone deacetylase family.

ZNF827 HDAC8 PRKDC HUWE1 XAB2

6.58e-0528951523752268
Pubmed

The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.

CPNE6 CPNE7

7.54e-0595129430674
Pubmed

Exportin 4: a mediator of a novel nuclear export pathway in higher eukaryotes.

EIF5AL1 XPO1

9.42e-051051210944119
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPN13 PTPRR

1.15e-04115127832766
Pubmed

Insulin receptor substrate-4 interacts with ubiquitin-specific protease 18 to activate the Jak/STAT signaling pathway.

PRKDC HUWE1

1.63e-041351229285303
Pubmed

Optimising experimental design for high-throughput phenotyping in mice: a case study.

EPC1 MYSM1

1.63e-041351220799038
Pubmed

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.

PRKDC XPO1 HUWE1

1.65e-047251336376293
Pubmed

A novel p53 regulator, C16ORF72/TAPR1, buffers against telomerase inhibition.

IPPK CCN6 HDAC8 ELF1 HUWE1

4.20e-0443151533660365
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SEPSECS NRDC PTPRR TMEM131L PRKDC XPO1 HUWE1

5.23e-0497451728675297
Pubmed

ETS-dependent regulation of a distal Gata4 cardiac enhancer.

ERF ELF1

5.70e-042451222056786
Pubmed

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV.

NRDC PRKDC

6.19e-042551215385968
Pubmed

Substrate specificities and identification of putative substrates of ATM kinase family members.

PRKDC RAD17

6.19e-042551210608806
Pubmed

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

ZC3H14 XAB2 THOC6

6.37e-0411451331553912
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

PIK3CG HDAC8 PRKDC XPO1

7.23e-0427651428319085
Pubmed

Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.

PRKDC XPO1 HUWE1

8.32e-0412551336030824
Pubmed

Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells.

CXCR6 PRKDC

8.35e-042951234678150
Pubmed

ETS-family genes in pancreatic development.

ERF ELF1

8.35e-042951217907201
Pubmed

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.

ERF ELF1

8.35e-042951226097038
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

ABCC4 PTPN13 TEX2 STXBP5 TMEM131L

8.50e-0450451534432599
Pubmed

Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.

PRKDC XPO1

8.93e-043051216449650
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SFMBT1 PTPN13 ERF PRKDC HUWE1 ARL14

9.34e-0477751635844135
Pubmed

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.

PHKA2 HDAC8

9.54e-043151214684825
Pubmed

BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.

ZC3H14 EPC1 XAB2

1.02e-0313451325452129
Pubmed

Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.

XPO1 RAD17

1.08e-033351216354571
Pubmed

Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality.

PTPN13 EPC1

1.08e-033351224159190
Pubmed

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics.

ZC3H14 PRKDC HUWE1

1.28e-0314551328846114
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

ITSN1 PRKDC HUWE1 MYSM1

1.43e-0333251437433992
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

PRKDC XPO1 HUWE1 XAB2

1.43e-0333251432786267
Cytoband9q22.31

IPPK ZNF484

4.17e-04275129q22.31
GeneFamilyCopines

CPNE6 CPNE7

1.23e-049342829
GeneFamilyETS transcription factor family

ERF ELF1

1.26e-0328342534
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

MYSM1 MYBL1

4.45e-0353342532
ToppCellILEUM-inflamed-(1)_Th17_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPN13 CXCR6 TMIGD2 ELF1 XPO1 CPNE7

8.84e-081935160663c57e1b8b8dd70d617d029fc7bdbbda8c1208
ToppCellCOVID-19-Lymphoid-CD4_T_cells|Lymphoid / Condition, Lineage and Cell class

GREM2 PTPN13 CXCR6 TMIGD2 MYBL1 CPNE7

9.68e-0819651628515d8e2f02366fa0ac1bea251a7a3f659c98c7
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SEPSECS CXCR6 ZNF827 TMIGD2 CPNE7

1.57e-06172515a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PHKA2 EIF5AL1 ZNF484 ZNF616 CPNE7

1.66e-06174515a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

ABCC4 TMEM131L PRKDC XPO1 HUWE1

2.24e-06185515a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

ABCC4 TMEM131L PRKDC XPO1 HUWE1

2.30e-061865158571956890fc9894d766ba294a28e376b4aba428
ToppCellNK-T_cells|World / lung cells shred on cell class, cell subclass, sample id

CXCR6 TMIGD2 XPO1 MYBL1 CPNE7

2.30e-06186515279ab91ebca37a39b8907409e07f8b533df67542
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPN13 CXCR6 TMIGD2 MYBL1 CPNE7

2.36e-06187515f1ba41f2ec703251a81c46e08d45e70210f298e7
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

ABCC4 TMEM131L PRKDC XPO1 HUWE1

2.62e-061915159454f642c3621370fa23640b631301346b300950
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Th17_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPN13 CXCR6 TMIGD2 XPO1 CPNE7

2.69e-0619251512f7ea575da5d650c740e6060f5dab0478e563dd
ToppCellILEUM-non-inflamed-(1)_Th17_Trm|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PTPN13 CXCR6 TMIGD2 ELF1 XPO1

2.69e-061925157347ff4dedd1aaa489c4f15e5ae647a4ce39ac72
ToppCellcontrol-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SEPSECS CXCR6 DCBLD1 MYSM1 MYBL1

2.76e-0619351589d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCellControl-MAIT|Control / Disease condition and Cell class

PTPN13 CXCR6 TMIGD2 MYBL1 CPNE7

2.83e-06194515ed99f8bff6766795fc396990604366f49ff58181
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CCN6 TCERG1L ZNF484 CXCR6

2.69e-05151514d19fc363ba1d7ff77e0adcaacafa4c64e1143f40
ToppCellCOVID-19_Moderate-MAIT|COVID-19_Moderate / disease group, cell group and cell class

PTPN13 CXCR6 MYBL1 CPNE7

3.30e-051595146d08d670c34eb6bb8ad5dad3293b3107c006236d
ToppCellCOVID-19_Moderate-MAIT|World / disease group, cell group and cell class

PTPN13 CXCR6 MYBL1 CPNE7

3.38e-05160514bf73c5fe87c1f243edec17d7a2c30fae5e2cfd6b
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|356C / Donor, Lineage, Cell class and subclass (all cells)

EIF5AL1 ZNF484 ZNF616 CPNE7

3.72e-05164514d5bb57c321f2973836efc8990449494cc1fb87c7
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN13 CXCR6 TMIGD2 MYBL1

3.90e-05166514bb93db4613c067c56614ab1ca39e73ee46484387
ToppCellICU-NoSEP-Lymphocyte-T_NK-MAIT|ICU-NoSEP / Disease, Lineage and Cell Type

CXCR6 TMIGD2 DCBLD1 CPNE7

3.90e-05166514d3fa2e42497201f1ca57f4f977fbaa0def950033
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN13 CXCR6 TMIGD2 MYBL1

3.90e-05166514c1f17a028bb27b8f202bcfffa7de7373b1cdd990
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHKA2 PTPN13 C11orf97 MYSM1

4.09e-051685142e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellControl-Lymphocyte-T_NK-MAIT|Control / Disease, Lineage and Cell Type

CXCR6 TMIGD2 MYBL1 CPNE7

4.18e-051695148c2aac193a9c500f01a99a2ee530839c851b6222
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCN6 CXCR6 ZNF827 NSL1

4.18e-05169514dbf9b1d52b29bf4b60bd23012cc1ea82d344747f
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like|bone_marrow / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

4.38e-051715142977cffc146470733b5cfd8a1aa80d9346d4804d
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Th1|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR6 TMIGD2 DNAH6 CPNE7

4.48e-05172514c0c9a3f5b5fb942b049bc159fd9f21b5b706edd2
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-MAIT|Multiple_Sclerosis / Disease, Lineage and Cell Type

CXCR6 TMIGD2 MYBL1 CPNE7

4.48e-0517251418bda0038cb37da6784e7bf7291272c108cfd9c5
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PHKA2 EIF5AL1 ZNF616 CPNE7

4.58e-05173514090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like|blood / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

4.69e-0517451451be6f29308c01593978cbee92114151a5916c9c
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

4.90e-0517651425c197d3b39deffa4801a1d12cdb54320cbae509
ToppCellMild-Lymphoid-T-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

PTPN13 CXCR6 TMIGD2 CPNE7

5.23e-05179514abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCellBAL-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN13 CXCR6 TMIGD2 MYBL1

5.35e-05180514163c34783f013b3904ae2d43b7edde4d55a3e2e5
ToppCellBAL-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PTPN13 CXCR6 TMIGD2 MYBL1

5.35e-0518051412cd0b1c8cdf4b11f057657e2196c20ed54d222a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPN13 TCERG1L DCBLD1 TMEM131L

5.35e-051805145e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th17|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR6 TMIGD2 MYBL1 CPNE7

5.70e-051835141ee09af56dac121c841d869021ca625dd3336b84
ToppCellNS-critical-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CXCR6 TMIGD2 MYBL1 CPNE7

5.70e-05183514f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

5.82e-05184514d97471a4fe17cba6880ccf1a04cc00c741558124
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th1|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPN13 CXCR6 TMIGD2 CPNE7

5.95e-05185514326c8b6ea0e9140616d7b867db1385b980dc3678
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CXCR6 TMIGD2 DNAH6 MYBL1

5.95e-05185514593eceb3dfcc662c892a840ba29ab687c6886c01
ToppCellControl-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

CXCR6 ZNF827 TMIGD2 MYBL1

6.07e-051865147bc939bf4e71bb4c6409b862c1f6c547d775e089
ToppCellHealthy-MAIT|Healthy / disease group, cell group and cell class

CXCR6 TMIGD2 MYBL1 CPNE7

6.07e-05186514028061f06d86e75cb06db56b199594b80f23fa58
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

GREM2 CXCR6 TMIGD2 MYBL1

6.07e-05186514927723ad579bbd9947ff525bd501e222d3fa9289
ToppCellILEUM-inflamed-(1)_Cytotoxic_CD8_Trm|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CXCR6 TMIGD2 MYBL1 CPNE7

6.33e-05188514d26894d1066a70e4b32ae41fff1c4718f2591ba9
ToppCell(1)_T_CD4|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CXCR6 ELF1 XPO1 CPNE7

6.46e-051895142298a96c53c5bd767e17554c50379b2d1ad8b5b0
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like|bone_marrow / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

6.46e-05189514ac2995e599f3d1813218479dc515b1d612c0ef8b
ToppCellHealthy-MAIT|World / disease group, cell group and cell class

CXCR6 TMIGD2 MYBL1 CPNE7

6.46e-051895142404254b7a31b4a931841232e07462a3ca855ad4
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

6.46e-05189514afe3a4fe7c10eeeb7064129778d940269c9acbef
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like|lymph-node_spleen / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

6.59e-051905140c7eb8f4f2926af01bf44d5c9f239be7b81c67fe
ToppCell-HP_01|World / lung cells shred on cell class, cell subclass, sample id

CXCR6 TMIGD2 XPO1 CPNE7

6.73e-051915146b20e6e296e792ad3b95e665ac3d6eb87424ecce
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-MAIT|bone_marrow / Manually curated celltypes from each tissue

CXCR6 TMIGD2 MYBL1 CPNE7

6.73e-051915147a28905ad504979497836e87df81d529e675ce78
ToppCellCOVID-19_Mild-Lymphoid_T/NK-MAIT|COVID-19_Mild / Disease group, lineage and cell class

CXCR6 TMIGD2 MYBL1 CPNE7

6.87e-05192514d47bd132e57f5b4bddcf3dfa399cee149eca7e44
ToppCellbackground-NK_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

CXCR6 PIK3CG TMIGD2 MYBL1

7.01e-05193514f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCellNS-moderate-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CXCR6 TMIGD2 MYBL1 CPNE7

7.01e-051935146115d43017070a78d335687bd039c08f00f77029
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD8-MAIT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR6 TMIGD2 MYBL1 CPNE7

7.01e-051935149aeb34d7a24f84abff38d7b8cf0ec707c08eb27f
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-0519551459164d115a0928cc9b79c7661c7190ad695f9d80
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514caa3669739974b63470f7e557df96e8d3844dd84
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A|343B / Donor, Lineage, Cell class and subclass (all cells)

CXCR6 TMIGD2 ELF1 MYBL1

7.29e-051955141af6fd96634236d5910fd085ff2d532862303d6b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514c7b54b210cc2c8ddaefebfba74381adb2ca698b8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514e173a713d273b135db4f71bdcaada3b0e55d74f1
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514279530c54eb1ada0297c64e12b33f9ffc3975c1e
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-051955147bde23821909a692d0bac4d01ee825ba2f95c0a0
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514bc5728e9df0b15adec50a7c840ce9f2775135087
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514145865d0a4e19435f3dcbfd626cbd25be17f92fb
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR6 TMIGD2 MYBL1 CPNE7

7.29e-05195514a8fd42ff6c2bd80d0e3f20fe3bbf7d113b399df1
ToppCellmoderate-Lymphoid-Treg|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PTPN13 CXCR6 TMIGD2 EPC1

7.44e-051965149152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell(1)_T_CD8_MAIT|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CXCR6 TMIGD2 MYBL1 CPNE7

7.44e-051965145fc99a8e3dde12fd0b0b2e0a2db48ac16b42739e
ToppCellParenchyma_Control_(B.)-Immune-TX-T_cells|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975143712eaa1d2ed200e0b0fdb2886f4cdf641fd2cdc
ToppCellnormal-na-Lymphocytic_NK-T_mait|normal / PBMC cell types (v2) per disease, treatment status, and sex

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975145abe983f9750085ec7b57bcb8c36bdfe78a6ee4c
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-0519751407475c0785534ba845acec0e33310d57ad7352e6
ToppCellnormal-na-Lymphocytic_NK-T_mait-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975148752c0f37979aa7bf2e8aee6990fb6307a6666b7
ToppCell(1)_T_cells-(1)_T_CD8_MAIT|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975140f01907d62c9c08cb54fe66c038f0adf7093e3c6
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

C11orf97 DNAH6 F12 ARL14

7.58e-05197514861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514aa160ebf2f1913b83e0b1ae1de1d9e2089342948
ToppCellBronchial-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975144bc76958ca12af2dd490d4865de6a92554a14656
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514185e9a6bd9894a050604a1af66c2fc39cf1f8d7a
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514486af69d2840d351790ee41dc7438c02c615740b
ToppCellTracheal-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-0519751453b20c439b9473b49011cd175d2770f12c472fc3
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514a4ecac6ee8a0d4d85319104c179ec7711a3efb51
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-T_mait|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514653f5cfc44bc3b9218fa187df3d1d828070c2d44
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK-Other_T-T_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975147effa80fa97a97906a9e8e8d00513bebfef0f980
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK-Other_T-T_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514af96ef0dbf89d4a2b78f48a1e1182b719025d67c
ToppCellLung_Parenchyma-Control-Lymphocyte-T/NK-Other_T|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-051975146153f14a457c0b8452729aa301e5486a539e9cba
ToppCellMild_COVID-19-T/NK-CD4+_T_1|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

PTPN13 CXCR6 TMIGD2 CPNE7

7.58e-0519751498fca0a2e2f66525c5c9d6cdaebcad14b4d53da4
ToppCellControl-Lymphoid-CD4_T_cells|Control / Condition, Lineage and Cell class

PTPN13 CXCR6 TMIGD2 MYBL1

7.58e-05197514dad6479caac07c1536f2b3082a51d61ae08beca0
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-MAIT|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR6 TMIGD2 MYBL1 CPNE7

7.58e-05197514b8535734a61b718ff17a6a374182f30c1d3bc86f
ToppCellTransverse-T_cell-Th17|T_cell / Region, Cell class and subclass

PTPN13 CXCR6 TMIGD2 MYBL1

7.73e-05198514918068ffd682c896c11d576072bde270630539d9
ToppCell(1)_T_cell-(13)_Th17|(1)_T_cell / shred on Cell_type and subtype

PTPN13 CXCR6 TMIGD2 MYBL1

7.73e-05198514a3ac65295da7baed447786a302b01db1cc824db2
ToppCellcontrol-MAIT|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CXCR6 TMIGD2 MYBL1 CPNE7

7.73e-0519851413955a4026c97e11d94973ac87bf018f64a2616c
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-T-T_CD4-CD4|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CXCR6 TMIGD2 MYBL1 CPNE7

7.73e-05198514cdb4d65a125a57a98287761d049cc34e6ae1d6bf
ToppCellSigmoid-T_cell-Th17|T_cell / Region, Cell class and subclass

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-05199514622f2ae4b1850b25f723a0385da49147dfec8285
ToppCellCaecum-(1)_T_cell-(13)_Th17|Caecum / shred on region, Cell_type, and subtype

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-05199514c67228b3e9e2afd8aa8b6c4358c3a27b0945eb29
ToppCellCaecum-T_cell-Th17|Caecum / Region, Cell class and subclass

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-05199514d0742a8c0aa15e68dce14c3cb46a65acf5afb702
ToppCellSigmoid-T_cell-Th17|Sigmoid / Region, Cell class and subclass

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-05199514ff9bbfead7a8c7d1ba910ff1f9c6eb9a9774264c
ToppCellSigmoid-(1)_T_cell-(13)_Th17|Sigmoid / shred on region, Cell_type, and subtype

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-051995141b39191481faf2e8646a1405e30d8579031bd368
ToppCell(22)_CD8+_T_cell|World / immune cells in Peripheral Blood (logTPM normalization)

CXCR6 TMIGD2 MYBL1 CPNE7

7.89e-05199514e1261507f0adade3ba534d5b465c9c559fc3aed0
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ABCC4 PTPN13 ZNF827 ZNF616

7.89e-05199514121de4e02585de3a3010398387c523bacf8ce546
ToppCellCOVID-19-Lymphoid-CD4_T_cells|COVID-19 / Condition, Lineage and Cell class

CXCR6 TMIGD2 MYBL1 CPNE7

7.89e-0519951427ac7ad2f4c2028c355632cbb81f2b52439b85ad
ToppCellTransverse-T_cell-Th17|Transverse / Region, Cell class and subclass

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-05199514640989e048b08d66c5020e032a61ef05f3831034
ToppCellTransverse-(1)_T_cell-(13)_Th17|Transverse / shred on region, Cell_type, and subtype

PTPN13 CXCR6 TMIGD2 MYBL1

7.89e-051995143b17c2704317cac0d641e673563098fd8ca19bd8
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-MAIT|Multiple_Sclerosis / Disease, condition lineage and cell class

CXCR6 TMIGD2 MYBL1 CPNE7

8.04e-0520051410120f474ac3de10fc8e66158969415bd3f8c1da
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PTPN13 CXCR6 TMIGD2 MYBL1

8.04e-052005147b39505b5e450a7e8a3eab2fd9c552891bd079ff
Diseasecraniosynostosis (is_implicated_in)

ERF ZIC1

1.84e-0412502DOID:2340 (is_implicated_in)
Diseaseresponse to irinotecan

ABCC4 DCBLD1

2.91e-0415502EFO_0004829
DiseaseSynostotic Posterior Plagiocephaly

ERF ZIC1

3.33e-0416502C1833340
DiseaseSynostotic Anterior Plagiocephaly

ERF ZIC1

3.33e-0416502C2931150
DiseaseMetopic synostosis

ERF ZIC1

3.33e-0416502C1860819
DiseaseCraniosynostosis, Type 1

ERF ZIC1

3.33e-0416502C4551902
DiseaseAcrocephaly

ERF ZIC1

3.33e-0416502C0030044
DiseaseTrigonocephaly

ERF ZIC1

3.33e-0416502C0265535
DiseaseScaphycephaly

ERF ZIC1

3.33e-0416502C0265534
DiseaseBrachycephaly

ERF ZIC1

3.77e-0417502C0221356
DiseaseCraniosynostosis

ERF ZIC1

5.24e-0420502C0010278
Diseasetemperament and character inventory

SEPSECS TCERG1L

7.58e-0424502EFO_0004825
Diseasegastric adenocarcinoma (is_marker_for)

PTPN13 XPO1

1.03e-0328502DOID:3717 (is_marker_for)
Diseaseage at menopause

PIK3CG PRKDC F12 GPR45

1.71e-03302504EFO_0004704
Diseasefactor VIII measurement

STXBP5 F12

2.11e-0340502EFO_0004630

Protein segments in the cluster

PeptideGeneStartEntry
LWGVRKCKPQMNYDK

ERF

66

P50548
EYWIKKRKNCRGPSL

EPC1

176

Q9H2F5
ALLQDKATCPKYIKW

ELF1

216

P32519
RKNFWKLVKDIGCLP

CXCR6

296

O00574
KVKKLCSDRNWYVQP

ARL14

141

Q8N4G2
QWDCINPKYRDKKKN

CPNE6

261

O95741
KPQWFLINKKYRENC

RAD17

526

O75943
TGKWKQISKYCPLDL

IPPK

171

Q9H8X2
LKGKKVPQYPCLWVN

KCNMB1

66

Q16558
LKRKQTKDCPQRKWY

NSL1

256

Q96IY1
KLNNVIYWERERKPK

OVOS2

1156

Q6IE36
KYLKSDWCKTQPLRQ

GREM2

66

Q9H772
TCIKNLWNRKPLKVY

HUWE1

1251

Q7Z6Z7
KSVFNPIVYCWRIKK

GPR45

316

Q9Y5Y3
EKNEKCVLYWPEKRG

PTPRR

496

Q15256
QKPSLTRAIIKCYWK

ABCC4

76

O15439
LGPIKWYKDCNEIKG

IL1RL2

156

Q9HB29
PAYRNLPLIWKKKCL

CCN6

196

O95389
LNLKLYCKEGKIPWD

DNAH6

3726

Q9C0G6
RKNGFVVLKGWPCKI

EIF5AL1

26

Q6IS14
AQWDCVNPKYKQKRR

CPNE7

336

Q9UBL6
KKRQIGWFPANYVKL

ITSN1

1121

Q15811
AWYQQKPGKVPKLLI

IGKV1-27

56

A0A075B6S5
KKYRKVWGIYDCQQP

CYP3A7

66

P24462
PVGIGKCLKYILQWQ

HDAC8

281

Q9BY41
QKTDCWKQIKYPFAR

DCBLD1

496

Q8N8Z6
YEVPQQKGLKKLWNR

MYBL1

21

P10243
PVGFYQRVWKILQKC

PHKA2

1081

P46019
KIKCQRYWPNILGKT

PTPN13

2316

Q12923
QDQRWGYCLEPKKVK

F12

81

P00748
KCWLRYIEFKQGAPK

XAB2

36

Q9HCS7
WKKYKNGDVCKRNVL

TMEM131L

546

A2VDJ0
WYPQLQRKKGVVLIK

SHLD2

646

Q86V20
ARQKRQGYSKKEWPI

STXBP5

421

Q5T5C0
GQQWKKFLYCEPHKR

C11orf97

46

A0A1B0GVM6
PLPEYLWKKIANNCI

PIK3CG

206

P48736
GKSWIDKRIPNCKIF

TCERG1L

151

Q5VWI1
WKILPRNQCEGIKKY

XPO1

91

O14980
WKCLEPVQKALYKDV

ZNF616

21

Q08AN1
RVKWTKDGAILCQPY

TMIGD2

56

Q96BF3
LKKGCKELWRRQPPY

THOC6

106

Q86W42
VKIVNTPQGCLWYKK

NRDC

681

O43847
TPQGCLWYKKDNKFK

NRDC

686

O43847
KNWYPRQKICYAKRK

PRKDC

4036

P78527
CPICGLVIKRKSYWK

ZNF827

376

Q17R98
YMRQPIKQELICKWI

ZIC1

216

Q15915
QKPYKCSDLGKALNW

ZNF484

801

Q5JVG2
KADLYPIGWCEQNKK

SFMBT1

101

Q9UHJ3
KAKYIIWPRIDQKSC

SEPSECS

161

Q9HD40
KRIWNKKYPICIELG

TEX2

626

Q8IWB9
AQKPEKLLERCKYWP

ZC3H14

591

Q6PJT7
KIRNYILDQWEICKP

MYSM1

411

Q5VVJ2
ILDQWEICKPKYLNK

MYSM1

416

Q5VVJ2