Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC24A5 TRPM6 ATP6V0C SLC22A25 SLC7A13 SLC37A3 SLC26A5 TMEM175 OTOP2 SLC5A7 SLC9B1P1 COX15 SLC10A3 SLC35B2 KCNK12 OCA2 TTYH3 SPNS3 PKD1L2 MFSD4B SLC9C2 SLC40A1 RHCE SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC7A4 SLC9A4 CACNG7 SLC12A2 SLCO1C1 ABCB10 SLC12A4 ATP2C2 TMC8 SLC15A5 KCNS1 SLC35F2 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 APOL2 SLC26A11 SLC2A12 SLC16A8 SLC38A8 GABRA5

7.31e-23118017051GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC24A5 TRPM6 ATP6V0C SLC22A25 SLC7A13 SLC37A3 SLC26A5 TMEM175 OTOP2 SLC5A7 SLC9B1P1 COX15 SLC10A3 SLC35B2 KCNK12 OCA2 TTYH3 SPNS3 PKD1L2 MFSD4B SLC9C2 SLC40A1 RHCE SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC7A4 SLC9A4 CACNG7 SLC12A2 SLCO1C1 ABCB10 SLC12A4 ATP2C2 TMC8 SLC15A5 KCNS1 SLC35F2 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 APOL2 SLC26A11 SLC2A12 SLC16A8 SLC38A8 GABRA5

3.69e-21128917051GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC24A5 TRPM6 ATP6V0C SLC37A3 SLC26A5 TMEM175 OTOP2 SLC5A7 COX15 SLC10A3 KCNK12 OCA2 TTYH3 PKD1L2 SLC9C2 SLC40A1 RHCE SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 APOL2 SLC26A11 GABRA5

2.53e-1775817036GO:0015318
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC24A5 SLC22A25 SLC7A13 SLC37A3 SLC26A5 SLC5A7 SLC9B1P1 SLC10A3 SLC35B2 MFSD4B SLC9C2 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLCO1C1 SLC12A4 SLC15A5 SLC26A11 SLC2A12 SLC16A8

7.14e-1729617024GO:0015291
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC24A5 ATP6V0C SLC22A25 SLC7A13 SLC37A3 SLC26A5 SLC5A7 SLC9B1P1 COX15 SLC10A3 SLC35B2 MFSD4B SLC9C2 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLCO1C1 ABCB10 SLC12A4 ATP2C2 SLC15A5 ATP1A3 SLC26A11 SLC2A12 SLC16A8

7.73e-1747717029GO:0022804
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC24A5 TRPM6 ATP6V0C SLC26A5 TMEM175 OTOP2 SLC5A7 COX15 SLC10A3 KCNK12 OCA2 TTYH3 PKD1L2 SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 TMC8 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 APOL2 SLC26A11 GABRA5

7.09e-1679317035GO:0015075
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 SLC5A7 COX15 SLC10A3 KCNK12 PKD1L2 SLC9C2 SLC40A1 RHCE SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

6.11e-1362717028GO:0022890
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC24A5 TRPM6 TMEM175 SLC5A7 SLC10A3 KCNK12 PKD1L2 SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

1.12e-1146517023GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 SLC5A7 COX15 SLC10A3 KCNK12 PKD1L2 SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

1.44e-1166417027GO:0008324
GeneOntologyMolecularFunctionsymporter activity

SLC24A5 SLC5A7 SLC10A3 MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC12A2 SLC12A4 SLC15A5 SLC2A12 SLC16A8

4.03e-1115017014GO:0015293
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC24A5 ATP6V0C SLC26A5 SLC5A7 COX15 SLC10A3 SLC9C2 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLC12A4 ATP2C2 ATP1A3 SLC26A11

1.07e-1030117018GO:0022853
GeneOntologyMolecularFunctionchannel activity

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 KCNK12 OCA2 TTYH3 PKD1L2 RHCE CACNG7 SLC12A2 SLC12A4 TMC8 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 APOL2 SLC26A11 GABRA5

7.60e-1052517022GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 KCNK12 OCA2 TTYH3 PKD1L2 RHCE CACNG7 SLC12A2 SLC12A4 TMC8 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 APOL2 SLC26A11 GABRA5

7.88e-1052617022GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 KCNK12 OCA2 TTYH3 PKD1L2 CACNG7 TMC8 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 APOL2 SLC26A11 GABRA5

1.45e-0845917019GO:0005216
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC24A5 SLC5A7 SLC10A3 SLC9C2 SLC5A1 SLC5A3 SLC5A11 SLC38A2 SLC9A4 SLC12A2 ASIC4 ATP1A3

2.68e-0817117012GO:0015081
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

5.40e-08251706GO:0015149
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

5.40e-08251706GO:0055056
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

8.90e-08271706GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

1.41e-07291706GO:0051119
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC5A7 SLC10A3 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC12A2 SLC12A4

8.25e-071191709GO:0015294
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC26A5 OCA2 TTYH3 SLC12A2 SLC12A4 MFSD8 APOL2 SLC26A11 GABRA5

1.25e-061251709GO:0015108
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

1.42e-06421706GO:0015144
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC24A5 TMEM175 KCNK12 SLC9C2 SLC9A4 SLC12A2 SLC12A4 KCNS1 KCNK6 ATP1A3

1.72e-0616717010GO:0015079
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR6S1 GPR27 GCGR OR8K3 PTGER2 OR6X1 OR10G6 OR8A1 TAS2R9 OR52L2P OR51M1 HPGD GPR149 OR52D1 OR10W1 TAS1R2 OR1K1 ADGRF5 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

1.83e-0688417023GO:0004930
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC37A3 SLC26A5 OCA2 TTYH3 SLC12A2 SLC12A4 MFSD8 APOL2 SLC26A11 GABRA5

2.13e-0617117010GO:0015103
GeneOntologyMolecularFunctionmyo-inositol transmembrane transporter activity

SLC5A1 SLC5A3 SLC5A11

2.41e-0641703GO:0005365
GeneOntologyMolecularFunctionantiporter activity

SLC24A5 SLC7A13 SLC37A3 SLC26A5 SLC9B1P1 SLC35B2 SLC9C2 SLC9A4 SLC26A11

2.85e-061381709GO:0015297
GeneOntologyMolecularFunctionolfactory receptor activity

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR52L2P OR51M1 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

4.44e-0643117015GO:0004984
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A7 SLC10A3 SLC5A1 SLC5A3 SLC5A11 SLC38A2 SLC12A2

5.87e-06811707GO:0015370
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC26A5 OCA2 TTYH3 SLC12A2 SLC12A4 MFSD8 APOL2 SLC26A11 GABRA5

5.96e-061511709GO:0008509
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC22A25 SLC7A13 SLC37A3 SLC26A5 SLC10A3 SLC35B2 SLC2A10 SLC38A2 SLCO1C1 SLC26A11 SLC16A8 SLC38A8

8.29e-0629317012GO:0008514
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR6S1 GPR27 GCGR OR8K3 PTGER2 IL1RL2 OR6X1 PTK7 OR10G6 OR8A1 TAS2R9 OR52L2P OR51M1 HPGD GPR149 OR52D1 OR10W1 TAS1R2 OR1K1 ADGRF5 OR52W1 LTK OR52M1 OR52Z1P OR51B2 OR51H1 SORL1 GABRA5

1.06e-05135317028GO:0004888
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC5A1 SLC5A3 SLC5A11 SLC2A10

1.11e-05171704GO:0005402
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A1 SLC5A3 SLC5A11

2.07e-0571703GO:0005412
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

SLC10A3 SLC5A1 SLC5A3 SLC5A11 SLCO1C1 SLC16A8

2.91e-05701706GO:1901618
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 KCNK12 PKD1L2 CACNG7 KCNS1 KCNK6 CACNG5 ASIC4

3.94e-0534317012GO:0005261
GeneOntologyMolecularFunctionmyo-inositol:sodium symporter activity

SLC5A1 SLC5A3

7.21e-0521702GO:0005367
GeneOntologyMolecularFunctionfucose transmembrane transporter activity

SLC5A1 SLC5A3

7.21e-0521702GO:0015150
GeneOntologyMolecularFunctionpentose transmembrane transporter activity

SLC5A1 SLC5A3

7.21e-0521702GO:0015146
GeneOntologyMolecularFunction4-hydroxybenzoate polyprenyltransferase activity

COQ2 UBIAD1

7.21e-0521702GO:0008412
GeneOntologyMolecularFunctionchloride channel activity

OCA2 TTYH3 MFSD8 APOL2 SLC26A11 GABRA5

9.33e-05861706GO:0005254
GeneOntologyMolecularFunctionammonium channel activity

RHCE SLC12A2 SLC12A4

1.26e-04121703GO:0008519
GeneOntologyMolecularFunctionpolyol transmembrane transporter activity

SLC5A1 SLC5A3 SLC5A11

1.63e-04131703GO:0015166
GeneOntologyMolecularFunctionpolyprenyltransferase activity

COQ2 UBIAD1

2.15e-0431702GO:0002094
GeneOntologyMolecularFunctionmonoatomic anion channel activity

OCA2 TTYH3 MFSD8 APOL2 SLC26A11 GABRA5

2.52e-041031706GO:0005253
GeneOntologyMolecularFunctionpotassium ion leak channel activity

TMEM175 KCNK12 KCNK6

3.13e-04161703GO:0022841
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC22A25 SLC7A13 SLC26A5 SLC10A3 SLC38A2 SLCO1C1 SLC16A8 SLC38A8

4.07e-042071708GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC22A25 SLC7A13 SLC26A5 SLC10A3 SLC38A2 SLCO1C1 SLC16A8 SLC38A8

4.20e-042081708GO:0005342
GeneOntologyMolecularFunctionmannose-ethanolamine phosphotransferase activity

PIGN PIGO

4.28e-0441702GO:0051377
GeneOntologyMolecularFunctionnarrow pore channel activity

TMEM175 KCNK12 KCNK6

5.31e-04191703GO:0022842
GeneOntologyMolecularFunctionleak channel activity

TMEM175 KCNK12 KCNK6

5.31e-04191703GO:0022840
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC24A5 SLC9C2 SLC9A4

5.31e-04191703GO:0022821
GeneOntologyMolecularFunctionprostaglandin E receptor activity

PTGER2 HPGD

7.09e-0451702GO:0004957
GeneOntologyMolecularFunctionproton transmembrane transporter activity

ATP6V0C TMEM175 OTOP2 COX15 SLC9C2 SLC2A10 SLC9A4

1.16e-031881707GO:0015078
GeneOntologyMolecularFunctionproton channel activity

ATP6V0C TMEM175 OTOP2

1.53e-03271703GO:0015252
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

SLC24A5 TRPM6 PKD1L2 CACNG7 ATP2C2 CACNG5

1.88e-031511706GO:0015085
GeneOntologyMolecularFunctiongated channel activity

KCNK12 TTYH3 CACNG7 TMC8 KCNS1 KCNK6 CACNG5 ASIC4 GABRA5

2.31e-033341709GO:0022836
GeneOntologyMolecularFunctionpotassium:chloride symporter activity

SLC12A2 SLC12A4

2.49e-0391702GO:0015379
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC37A3 SLC26A5 SLC26A11

2.51e-03321703GO:0005452
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP6V0C ATP2C2 ATP1A3

3.52e-03361703GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP6V0C ATP2C2 ATP1A3

3.52e-03361703GO:0015662
GeneOntologyMolecularFunctionepoxide hydrolase activity

RNPEP EPHX3

3.77e-03111702GO:0004301
GeneOntologyMolecularFunctionsecondary active sulfate transmembrane transporter activity

SLC26A5 SLC26A11

3.77e-03111702GO:0008271
GeneOntologyMolecularFunctionprostaglandin receptor activity

PTGER2 HPGD

3.77e-03111702GO:0004955
GeneOntologyMolecularFunctionprostanoid receptor activity

PTGER2 HPGD

4.50e-03121702GO:0004954
GeneOntologyMolecularFunctioncalcium channel activity

SLC24A5 TRPM6 PKD1L2 CACNG7 CACNG5

4.97e-031291705GO:0005262
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A5 SLC26A11

5.28e-03131702GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A5 SLC26A11

5.28e-03131702GO:0140829
GeneOntologyMolecularFunctionhydrolase activity, acting on ether bonds

RNPEP EPHX3

5.28e-03131702GO:0016801
GeneOntologyMolecularFunctionether hydrolase activity

RNPEP EPHX3

5.28e-03131702GO:0016803
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC24A5 SLC9C2 SLC9A4

5.83e-03431703GO:0140828
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9C2 SLC9A4

6.13e-03141702GO:0015386
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC24A5 TRPM6 ATP6V0C SLC37A3 SLC26A5 TMEM175 OTOP2 SLC9B1P1 COX15 KCNK12 OCA2 TTYH3 PKD1L2 SLC9C2 SLC40A1 RHCE SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 SLC26A11 GABRA5

7.93e-12101716833GO:0098660
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC24A5 TRPM6 ATP6V0C SLC22A25 SLC26A5 TMEM175 OTOP2 SLC5A7 CDH23 SLC9B1P1 COX15 KCNK12 OCA2 TTYH3 PKD1L2 MFSD4B SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLCO1C1 SLC12A4 ATP2C2 TMC8 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 SLC26A11 GABRA5

1.88e-11137416838GO:0006811
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC24A5 TRPM6 ATP6V0C SLC26A5 TMEM175 OTOP2 SLC9B1P1 COX15 KCNK12 OCA2 TTYH3 PKD1L2 SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 TMC8 KCNS1 KCNK6 CACNG5 MFSD8 ASIC4 ATP1A3 SLC26A11 GABRA5

3.95e-10111516832GO:0034220
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 SLC9B1P1 COX15 KCNK12 PKD1L2 SLC9C2 SLC40A1 RHCE SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

3.11e-0892216826GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 SLC5A7 CDH23 SLC9B1P1 COX15 KCNK12 PKD1L2 MFSD4B SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

5.88e-08115716829GO:0006812
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC37A3 SLC26A5 OCA2 TTYH3 SLC5A1 SLC12A2 SLC12A4 MFSD8 SLC26A11 GABRA5

1.50e-0713416810GO:0098661
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC24A5 TRPM6 ATP6V0C TMEM175 OTOP2 SLC9B1P1 COX15 KCNK12 PKD1L2 SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

1.88e-0794216825GO:0098655
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 TAS2R9 SLC12A2 OR52L2P OR51M1 OR52D1 OR10W1 PCDH15 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.97e-0758216819GO:0050906
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC26A5 OCA2 TTYH3 SLC5A1 SLC12A2 SLC12A4 MFSD8 SLC26A11 GABRA5

3.41e-071121689GO:1902476
GeneOntologyBiologicalProcesssodium ion transport

SLC24A5 SLC5A7 SLC9B1P1 MFSD4B SLC9C2 SLC5A1 SLC5A3 SLC5A11 SLC38A2 SLC9A4 SLC12A2 ASIC4 ATP1A3

4.27e-0727516813GO:0006814
GeneOntologyBiologicalProcessdetection of stimulus

OR6S1 TRB OR8K3 PKD1L2 OR6X1 OR10G6 OR8A1 TAS2R9 SLC12A2 OR52L2P OR51M1 OR52D1 OR10W1 PCDH15 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

4.55e-0772216821GO:0051606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 TAS2R9 OR52L2P OR51M1 OR52D1 OR10W1 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

4.89e-0748516817GO:0050907
GeneOntologyBiologicalProcessmetal ion transport

SLC24A5 TRPM6 TMEM175 SLC5A7 CDH23 SLC9B1P1 KCNK12 PKD1L2 MFSD4B SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC38A2 SLC9A4 CACNG7 SLC12A2 SLC12A4 ATP2C2 KCNS1 KCNK6 CACNG5 ASIC4 ATP1A3

5.70e-07100016825GO:0030001
GeneOntologyBiologicalProcessregulation of intracellular pH

ATP6V0C LRRK2 TMEM199 TMEM175 SLC9B1P1 OCA2 SLC9C2 SLC9A4

1.01e-06941688GO:0051453
GeneOntologyBiologicalProcesschloride transport

SLC26A5 OCA2 TTYH3 SLC5A1 SLC12A2 SLC12A4 MFSD8 SLC26A11 GABRA5

1.06e-061281689GO:0006821
GeneOntologyBiologicalProcessorganic anion transport

SLC22A25 SLC7A13 SLC37A3 SLC26A5 SLC10A3 SLC35B2 TTYH3 SLC2A10 SLC38A2 SLC12A2 SLCO1C1 CD47 PLA2G4F ATP1A3 SLC26A11 SLC16A8 SLC38A8

1.12e-0651516817GO:0015711
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 TAS2R9 OR52L2P OR51M1 OR52D1 OR10W1 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

1.42e-0652416817GO:0009593
GeneOntologyBiologicalProcessregulation of cellular pH

ATP6V0C LRRK2 TMEM199 TMEM175 SLC9B1P1 OCA2 SLC9C2 SLC9A4

1.74e-061011688GO:0030641
GeneOntologyBiologicalProcessinorganic anion transport

SLC37A3 SLC26A5 OCA2 TTYH3 SLC5A1 SLC12A2 SLC12A4 MFSD8 SLC26A11 GABRA5

2.28e-0618016810GO:0015698
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 TAS2R9 OR52L2P OR51M1 OR52D1 OR10W1 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.53e-0654716817GO:0007606
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR52L2P OR51M1 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.67e-0643216815GO:0050911
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC26A5 OCA2 TTYH3 SLC5A1 SLC12A2 SLC12A4 MFSD8 SLC26A11 GABRA5

4.65e-061531689GO:0098656
GeneOntologyBiologicalProcessmyo-inositol transport

SLC5A1 SLC5A3 SLC5A11

5.24e-0651683GO:0015798
GeneOntologyBiologicalProcessregulation of lysosomal lumen pH

ATP6V0C LRRK2 TMEM199 TMEM175 OCA2

5.69e-06321685GO:0035751
GeneOntologyBiologicalProcessregulation of pH

ATP6V0C LRRK2 TMEM199 TMEM175 SLC9B1P1 OCA2 SLC9C2 SLC9A4

6.35e-061201688GO:0006885
GeneOntologyBiologicalProcesssensory perception of smell

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR52L2P OR51M1 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

6.50e-0646516815GO:0007608
GeneOntologyBiologicalProcesssensory perception

OR6S1 SLC26A5 CDH23 OR8K3 OR6X1 OR10G6 OR8A1 TAS2R9 SLC12A2 HMCN1 LRIG1 OR52L2P OR51M1 OR52D1 OR10W1 PCDH15 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 SLC38A8 OR51H1

6.59e-06107216824GO:0007600
GeneOntologyBiologicalProcessproton transmembrane transport

ATP6V0C TMEM175 OTOP2 SLC9B1P1 COX15 SLC9C2 SLC2A10 SLC9A4 ATP1A3

1.09e-051701689GO:1902600
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC26A5 OCA2 TTYH3 SLC5A1 SLC12A2 SLC12A4 MFSD8 SLC26A11 GABRA5

1.97e-051831689GO:0006820
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

SLC24A5 TMEM175 KCNK12 SLC9C2 SLC9A4 SLC12A2 SLC12A4 KCNS1 KCNK6 ATP1A3

2.13e-0523216810GO:0071805
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC24A5 SLC9C2 SLC5A1 SLC5A3 SLC38A2 SLC9A4 SLC12A2 ASIC4 ATP1A3

5.38e-052081689GO:0035725
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR6S1 GPR27 LRRK2 GCGR OR8K3 PTGER2 OR6X1 AREG OR10G6 OR8A1 TAS2R9 OR52L2P OR51M1 HPGD GPR149 OR52D1 OR10W1 TAS1R2 OR1K1 ADGRF5 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1 SORL1

6.29e-05139516826GO:0007186
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

SLC9C2 SLC5A1 SLC9A4 SLC12A2

6.44e-05271684GO:0098719
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

SLC24A5 ATP6V0C LRRK2 TMEM199 TMEM175 CDH23 SLC9B1P1 OCA2 SLC9C2 SLC40A1 RHCE SLC9A4 SLC12A2 SLC12A4 ATP2C2 TMC8 ATP1A3

6.59e-0570516817GO:0055080
GeneOntologyBiologicalProcessfucose transmembrane transport

SLC5A1 SLC5A3

6.60e-0521682GO:0015756
GeneOntologyBiologicalProcesspentose transmembrane transport

SLC5A1 SLC5A3

6.60e-0521682GO:0015750
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC12A2 SLCO1C1

7.82e-05871686GO:0150104
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

SLC24A5 ATP6V0C LRRK2 TMEM199 TMEM175 CDH23 SLC9B1P1 OCA2 SLC9C2 SLC40A1 RHCE SLC9A4 SLC12A2 SLC12A4 ATP2C2 TMC8 ATP1A3

8.10e-0571716817GO:0050801
GeneOntologyBiologicalProcesspotassium ion transport

SLC24A5 TMEM175 KCNK12 SLC9C2 SLC9A4 SLC12A2 SLC12A4 KCNS1 KCNK6 ATP1A3

8.15e-0527216810GO:0006813
GeneOntologyBiologicalProcessvascular transport

SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC12A2 SLCO1C1

8.33e-05881686GO:0010232
GeneOntologyBiologicalProcessregulation of ER to Golgi vesicle-mediated transport

LRRK2 RNF139 SORL1

1.11e-04121683GO:0060628
GeneOntologyBiologicalProcessimport across plasma membrane

SLC9C2 SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLC12A4 ATP1A3

1.16e-042301689GO:0098739
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC7A13 SLC26A5 SLC10A3 TTYH3 SLC38A2 SLC12A2 SLCO1C1 PLA2G4F ATP1A3 SLC26A11 SLC16A8 SLC38A8

1.41e-0441016812GO:0046942
GeneOntologyBiologicalProcessammonium transmembrane transport

RHCE SLC12A2 SLC12A4

1.43e-04131683GO:0072488
GeneOntologyBiologicalProcesscarbohydrate transport

SLC37A3 SLC26A5 MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

1.47e-041861688GO:0008643
GeneOntologyBiologicalProcessorganic acid transport

SLC7A13 SLC26A5 SLC10A3 TTYH3 SLC38A2 SLC12A2 SLCO1C1 PLA2G4F ATP1A3 SLC26A11 SLC16A8 SLC38A8

1.47e-0441216812GO:0015849
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

SLC24A5 ATP6V0C LRRK2 TMEM199 TMEM175 CDH23 SLC9B1P1 OCA2 SLC9C2 SLC40A1 SLC9A4 SLC12A2 ATP2C2 TMC8 ATP1A3

1.48e-0461116815GO:0030003
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

SLC24A5 ATP6V0C LRRK2 TMEM199 TMEM175 CDH23 SLC9B1P1 OCA2 SLC9C2 SLC40A1 SLC9A4 SLC12A2 ATP2C2 TMC8 ATP1A3

1.80e-0462216815GO:0006873
GeneOntologyBiologicalProcesshexose transmembrane transport

SLC26A5 MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

2.42e-041511687GO:0008645
GeneOntologyBiologicalProcessmonosaccharide transmembrane transport

SLC26A5 MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

2.73e-041541687GO:0015749
GeneOntologyBiologicalProcessSREBP signaling pathway

AMFR ERLIN1 SCAP

2.75e-04161683GO:0032933
GeneOntologyBiologicalProcesscellular response to sterol depletion

AMFR ERLIN1 SCAP

3.32e-04171683GO:0071501
GeneOntologyBiologicalProcesslysosomal lumen pH elevation

TMEM175 OCA2

3.91e-0441682GO:0035752
GeneOntologyBiologicalProcesstransepithelial ammonium transport

SLC9A4 SLC12A2

3.91e-0441682GO:0070634
GeneOntologyBiologicalProcesslytic vacuole organization

ATP6V0C LRRK2 TMEM199 TMEM175 OCA2 MFSD8

4.34e-041191686GO:0080171
GeneOntologyBiologicalProcesslysosome organization

ATP6V0C LRRK2 TMEM199 TMEM175 OCA2 MFSD8

4.34e-041191686GO:0007040
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC7A13 SLC26A5 TTYH3 SLC38A2 SLC12A2 SLC26A11

4.54e-041201686GO:0006835
GeneOntologyBiologicalProcesscarbohydrate transmembrane transport

SLC26A5 MFSD4B SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC2A12

4.62e-041681687GO:0034219
GeneOntologyBiologicalProcessresponse to sterol depletion

AMFR ERLIN1 SCAP

4.67e-04191683GO:0006991
GeneOntologyBiologicalProcessresponse to potassium ion

SLC26A5 SLC12A2 ATP1A3

6.34e-04211683GO:0035864
GeneOntologyBiologicalProcessD-glucose import across plasma membrane

SLC5A1 SLC2A10

6.49e-0451682GO:0098708
GeneOntologyBiologicalProcessprotein retention in Golgi apparatus

VPS13C SORL1

6.49e-0451682GO:0045053
GeneOntologyBiologicalProcesscarbohydrate import across plasma membrane

SLC5A1 SLC2A10

9.68e-0461682GO:0098704
GeneOntologyBiologicalProcesshexose import across plasma membrane

SLC5A1 SLC2A10

9.68e-0461682GO:0140271
GeneOntologyBiologicalProcessgalactose transmembrane transport

SLC5A1 SLC2A10

9.68e-0461682GO:0015757
GeneOntologyBiologicalProcessresponse to mechanical stimulus

CRADD SLC26A5 PKD1L2 CHUK SLC38A2 SLC12A2 NFKBIA PCDH15

9.70e-042471688GO:0009612
GeneOntologyBiologicalProcesserythrocyte development

RHCE ABCB10 FAM210B ADGRF5

1.05e-03551684GO:0048821
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC9C2 SLC5A1 SLC9A4 SLC12A2 SLC12A4 ATP1A3

1.10e-031421686GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC9C2 SLC5A1 SLC9A4 SLC12A2 SLC12A4 ATP1A3

1.10e-031421686GO:0098659
GeneOntologyBiologicalProcesscellular homeostasis

SLC24A5 ATP6V0C GPR27 LRRK2 TMEM199 TMEM175 CDH23 SLC9B1P1 OCA2 SLC9C2 SLC40A1 SLC2A10 SLC9A4 SLC12A2 SLC12A4 ATP2C2 TMC8 ATP1A3

1.10e-0398116818GO:0019725
GeneOntologyCellularComponentendoplasmic reticulum membrane

POMT2 PIGN AMFR SLC37A3 VPS13C MARCHF6 LRRK2 TMEM199 ATL3 SLC35B2 OCA2 ERMP1 ELOVL2 ERLIN1 AREG OR8A1 NBAS SCAP OR51M1 TMEM147 TMC8 UBIAD1 RNF139 APOL2 PIGO SORL1

2.35e-05129317326GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

POMT2 PIGN AMFR SLC37A3 VPS13C MARCHF6 LRRK2 TMEM199 ATL3 SLC35B2 OCA2 ERMP1 ELOVL2 ERLIN1 AREG OR8A1 NBAS SCAP OR51M1 TMEM147 TMC8 UBIAD1 RNF139 APOL2 PIGO SORL1

2.54e-05129917326GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

POMT2 PIGN AMFR SLC37A3 VPS13C MARCHF6 LRRK2 TMEM199 ATL3 SLC35B2 OCA2 ERMP1 ELOVL2 ERLIN1 AREG OR8A1 NBAS SCAP OR51M1 TMEM147 TMC8 UBIAD1 RNF139 APOL2 PIGO SORL1

3.64e-05132717326GO:0042175
GeneOntologyCellularComponentbasolateral plasma membrane

SLC22A25 SLC26A5 SLC40A1 SLC5A3 SLC9A4 SLC12A2 SLCO1C1 HPGD ATP2C2 SLC26A11 SLC16A8

7.60e-0532017311GO:0016323
GeneOntologyCellularComponentbasal plasma membrane

SLC22A25 SLC26A5 SLC40A1 SLC5A3 SLC9A4 SLC12A2 SLCO1C1 HPGD ATP2C2 SLC26A11 SLC16A8

1.84e-0435417311GO:0009925
GeneOntologyCellularComponentbasal part of cell

SLC22A25 SLC26A5 SLC40A1 SLC5A3 SLC9A4 SLC12A2 SLCO1C1 HPGD ATP2C2 SLC26A11 SLC16A8

3.23e-0437817311GO:0045178
MousePhenoabnormal outer hair cell kinocilium location or orientation

CDH23 PTK7 PCDH15

1.50e-0561293MP:0030961
MousePhenovestibular saccular degeneration

CDH23 SLC12A2 PCDH15

2.62e-0571293MP:0004329
MousePhenodecreased circulating aspartate transaminase level

AMFR G0S2 TMEM212 LRIG1 FBXO42 SLC38A8

4.09e-05691296MP:0005632
MousePhenoabnormal outer hair cell kinocilium morphology

CDH23 PTK7 PCDH15

8.79e-05101293MP:0011062
MousePhenoabnormal cochlear outer hair cell number

NOG SLC26A5 CDH23 PTK7 SLC12A2

9.40e-05501295MP:0004400
MousePhenoabnormal cochlear inner hair cell morphology

NOG SLC26A5 CDH23 PTK7 SLC12A2 PCDH15 GABRA5

1.49e-041241297MP:0004393
MousePhenoabnormal cochlear inner hair cell number

NOG CDH23 PTK7 SLC12A2

1.57e-04301294MP:0004394
MousePhenoabnormal orientation of inner hair cell stereociliary bundles

CDH23 PTK7 PCDH15

1.59e-04121293MP:0004492
DomainMFS_dom

SLC22A25 SLC37A3 SPNS3 MFSD4B SLC40A1 SLC2A10 SLCO1C1 SLC15A5 MFSD8 SLC2A12 SLC16A8

3.14e-0813416611IPR020846
DomainNA_SOLUT_SYMP_1

SLC5A7 SLC5A1 SLC5A3 SLC5A11

1.89e-06111664PS00456
DomainSSF

SLC5A7 SLC5A1 SLC5A3 SLC5A11

2.82e-06121664PF00474
DomainNA_SOLUT_SYMP_2

SLC5A7 SLC5A1 SLC5A3 SLC5A11

2.82e-06121664PS00457
DomainNa/solute_symporter

SLC5A7 SLC5A1 SLC5A3 SLC5A11

2.82e-06121664IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A7 SLC5A1 SLC5A3 SLC5A11

2.82e-06121664PS50283
DomainMFS

SLC22A25 SLC37A3 SPNS3 SLC2A10 SLCO1C1 MFSD8 SLC2A12 SLC16A8

5.45e-061081668PS50850
DomainAA-permease/SLC12A_dom

SLC7A13 SLC7A4 SLC12A2 SLC12A4

3.89e-05221664IPR004841
DomainAA_permease

SLC7A13 SLC7A4 SLC12A2 SLC12A4

3.89e-05221664PF00324
DomainOlfact_rcpt

OR6S1 OR8K3 OR3A4P OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR51B2

5.13e-0539316613IPR000725
DomainMFS_1

SLC22A25 SLC37A3 SPNS3 MFSD4B MFSD8 SLC16A8

6.34e-05771666PF07690
DomainMFS

SLC22A25 SLC37A3 SPNS3 MFSD4B MFSD8 SLC16A8

6.34e-05771666IPR011701
DomainG_PROTEIN_RECEP_F1_2

OR6S1 GPR27 OR8K3 OR3A4P PTGER2 OR6X1 OR10G6 OR8A1 TAS2R9 OR51M1 GPR149 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR51B2

1.47e-0469116617PS50262
DomainGPCR_Rhodpsn

OR6S1 GPR27 OR8K3 OR3A4P PTGER2 OR6X1 OR10G6 OR8A1 TAS2R9 OR51M1 GPR149 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR51B2

1.49e-0469216617IPR000276
DomainUBIA

COQ2 UBIAD1

2.34e-0431662PS00943
DomainUbiA_prenyltransferase

COQ2 UBIAD1

2.34e-0431662IPR000537
DomainUbiA

COQ2 UBIAD1

2.34e-0431662PF01040
DomainDUF3523

ATAD3B ATAD3A

2.34e-0431662IPR021911
DomainDUF3523

ATAD3B ATAD3A

2.34e-0431662PF12037
DomainCPSF_A

SF3B3 CPSF1

2.34e-0431662PF03178
DomainCleavage/polyA-sp_fac_asu_C

SF3B3 CPSF1

2.34e-0431662IPR004871
Domain7tm_1

OR6S1 GPR27 OR8K3 OR3A4P PTGER2 OR6X1 OR10G6 OR8A1 OR51M1 GPR149 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR51B2

3.61e-0467716616PF00001
DomainG_PROTEIN_RECEP_F1_1

OR6S1 GPR27 OR8K3 OR3A4P PTGER2 OR6X1 OR10G6 OR8A1 OR51M1 GPR149 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR51B2

4.11e-0468516616PS00237
DomainGPCR_Rhodpsn_7TM

OR6S1 GPR27 OR8K3 PTGER2 OR6X1 OR8A1 TAS2R9 OR51M1 GPR149 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR51B2

9.60e-0467016615IPR017452
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC24A5 SLC5A7 SLC35B2 MFSD4B SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLCO1C1 SLC12A4 SLC26A11 SLC2A12 SLC16A8

7.64e-1124912617M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC24A5 TRPM6 ATP6V0C PSMA5 SLC5A7 SLC35B2 TTYH3 MFSD4B SLC9C2 SLC40A1 ERLIN1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLCO1C1 ABCB10 SLC12A4 ATP2C2 ASIC4 ATP1A3 SLC26A11 SLC2A12 SLC16A8

2.56e-1073612627M27287
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC24A5 SLC5A7 SLC35B2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLCO1C1 SLC12A4 SLC26A11 SLC2A12 SLC16A8

3.61e-1023812616MM15076
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC24A5 TRPM6 ATP6V0C PSMA5 SLC5A7 SLC9B1P1 SLC35B2 TTYH3 SLC40A1 ERLIN1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC9A4 SLC12A2 SLCO1C1 SLC12A4 ATP2C2 ASIC4 ATP1A3 SLC26A11 SLC2A12 SLC16A8

1.31e-0968112625MM14985
PathwayREACTOME_SENSORY_PERCEPTION

OR6S1 SLC26A5 CDH23 OR8K3 OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 CLPS OR10W1 PCDH15 TAS1R2 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

3.56e-0663612619M41834
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 OR10W1 OR1K1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.13e-0541712614M4072
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

MFSD4B SLC5A1 SLC2A10 SLC2A12

3.24e-05211264M27058
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 OR10W1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.10e-083401751311875048
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 OR10W1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.33e-083431751332295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR6S1 OR8K3 OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 OR10W1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

2.58e-083461751314611657
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLC7A13 SLC26A5 SLC7A4 SLC9A4 SOHLH2 SLC12A2 SLCO1C1 SLC26A11 SLC2A12 SORL1

1.37e-072121751019521566
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8K3 OR6X1 OR10G6 OR8A1 OR51M1 OR52D1 OR10W1 OR52W1 OR52M1 OR52Z1P OR51B2 OR51H1

1.77e-073401751211802173
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

PLEKHG4 TRO PSMA5 TMEM199 ERMP1 TTYH3 AREG HSPA13 SLC38A2 INTS5 NRSN2 SCAP ABCB10 SLC12A4 RNPEP MFSD8 UBIAD1 UBE3C DOCK6 PIGO

4.53e-0710611752033845483
Pubmed

The human olfactory receptor gene family.

OR6S1 OR8K3 OR3A4P OR6X1 OR10G6 OR8A1 OR52L2P OR51M1 OR52D1 OR10W1 OR52W1 OR52M1 OR52Z1P OR51H1

7.10e-075411751414983052
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR51M1 OR52D1 OR52Z1P OR51B2

8.10e-0715175411121057
Pubmed

Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes.

OR51M1 OR52D1 OR52Z1P OR51B2

8.10e-0715175410220430
Pubmed

KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability.

SLC5A1 SLC5A3 SLC5A11

1.24e-065175324595108
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

AMFR TMEM175 ATL3 SLC35B2 ERLIN1 PTK7 SLC5A3 SLC38A2 SLC12A4 ATAD3A TMEM87B UBIAD1 PIGO

1.67e-064991751322810586
Pubmed

Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.

AMFR ERLIN1 SCAP

4.32e-067175324217618
Pubmed

Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.

SLC26A5 CDH23 PCDH15

1.03e-059175319339464
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC5A1 SLC5A3 SLC2A10 SLC38A2 SLC12A2 SLCO1C1

1.59e-05105175630280653
Pubmed

Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.

COX15 RDH13 TAOK2 ABCB10 SLC12A4 ATAD3A

1.68e-05106175633087821
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

AMFR SLC35B2 ERLIN1 PTK7 TAOK2 SLC38A2 ATAD3B INTS5 NRSN2 SCAP SLC12A2 ABCB10 LRIG1 ATAD3A UBIAD1 ATP1A3

2.44e-059421751631073040
Pubmed

Gabra5-gene haplotype block associated with behavioral properties of the full agonist benzodiazepine chlordiazepoxide.

OCA2 GABRA5

2.52e-052175222677273
Pubmed

Sodium/myo-Inositol transporters: substrate transport requirements and regional brain expression in the TgCRND8 mouse model of amyloid pathology.

SLC5A3 SLC5A11

2.52e-052175221887366
Pubmed

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction.

CDH23 PCDH15

2.52e-052175223135401
Pubmed

Interpreting an apoptotic corpse as anti-inflammatory involves a chloride sensing pathway.

SLC12A2 SLC12A4

2.52e-052175231792382
Pubmed

Using thermal scanning assays to test protein-protein interactions of inner-ear cadherins.

CDH23 PCDH15

2.52e-052175229261728
Pubmed

A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells.

CDH23 PCDH15

2.52e-052175219270079
Pubmed

Allelic hierarchy of CDH23 mutations causing non-syndromic deafness DFNB12 or Usher syndrome USH1D in compound heterozygotes.

CDH23 PCDH15

2.52e-052175221940737
Pubmed

Molecular characterization of the tumor-associated antigen AAA-TOB3.

ATAD3B ATAD3A

2.52e-052175216909202
Pubmed

Prostaglandin E2 regulates its own inactivating enzyme, 15-PGDH, by EP2 receptor-mediated cervical cell-specific mechanisms.

PTGER2 HPGD

2.52e-052175224471568
Pubmed

Digenic inheritance of deafness caused by mutations in genes encoding cadherin 23 and protocadherin 15 in mice and humans.

CDH23 PCDH15

2.52e-052175215537665
Pubmed

Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappaB signaling pathway in B lymphocytes.

CHUK NFKBIA

2.52e-052175211042193
Pubmed

Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis.

CHUK NFKBIA

2.52e-052175212730857
Pubmed

A novel missense mutation locus of cadherin 23 and the interaction of cadherin 23 and protocadherin 15 in a patient with usher syndrome.

CDH23 PCDH15

2.52e-052175232835555
Pubmed

IkappaBalpha promoter polymorphisms in patients with primary Sjögren's syndrome.

CHUK NFKBIA

2.52e-052175218600435
Pubmed

Double homozygous waltzer and Ames waltzer mice provide no evidence of retinal degeneration.

CDH23 PCDH15

2.52e-052175219057657
Pubmed

The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression.

CACNG7 CACNG5

2.52e-052175211927536
Pubmed

IFNalpha/beta promotes cell survival by activating NF-kappa B.

CHUK NFKBIA

2.52e-052175211095741
Pubmed

Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.

CDH23 PCDH15

2.52e-052175221532990
Pubmed

Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues.

SLC2A10 SLC2A12

2.52e-052175212890477
Pubmed

ATAD 3A and ATAD 3B are distal 1p-located genes differentially expressed in human glioma cell lines and present in vitro anti-oncogenic and chemoresistant properties.

ATAD3B ATAD3A

2.52e-052175218639545
Pubmed

Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.

CHUK NFKBIA

2.52e-052175216219905
Pubmed

Nitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signaling.

CHUK NFKBIA

2.52e-052175218074035
Pubmed

Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression.

CHUK NFKBIA

2.52e-052175216493072
Pubmed

Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.

CDH23 PCDH15

2.52e-052175220739546
Pubmed

Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia.

AREG LRIG1

2.52e-052175225794708
Pubmed

Study of USH1 splicing variants through minigenes and transcript analysis from nasal epithelial cells.

CDH23 PCDH15

2.52e-052175223451239
Pubmed

The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization.

ATAD3B ATAD3A

2.52e-052175217210950
Pubmed

New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors.

CACNG7 CACNG5

2.52e-052175217475805
Pubmed

Human sodium/inositol cotransporter 2 (SMIT2) transports inositols but not glucose in L6 cells.

SLC5A3 SLC5A11

2.52e-052175219032932
Pubmed

Structural studies on 24P-IkappaBalpha peptide derived from a human IkappaB-alpha protein related to the inhibition of the activity of the transcription factor NF-kappaB.

CHUK NFKBIA

7.53e-053175217319651
Pubmed

Measles virus V protein is a decoy substrate for IkappaB kinase alpha and prevents Toll-like receptor 7/9-mediated interferon induction.

CHUK NFKBIA

7.53e-053175218922877
Pubmed

Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.

AMFR SCAP

7.53e-053175217043353
Pubmed

ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.

ATAD3B ATAD3A

7.53e-053175228549128
Pubmed

Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts.

CHUK NFKBIA

7.53e-053175218501560
Pubmed

Gpnmb secreted from liver promotes lipogenesis in white adipose tissue and aggravates obesity and insulin resistance.

AMFR SCAP

7.53e-053175232694855
Pubmed

ATAD3B is a human embryonic stem cell specific mitochondrial protein, re-expressed in cancer cells, that functions as dominant negative for the ubiquitous ATAD3A.

ATAD3B ATAD3A

7.53e-053175222664726
Pubmed

ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte-like 3T3-L1 cells.

ATAD3B ATAD3A

7.53e-053175238923254
Pubmed

W346 inhibits cell growth, invasion, induces cycle arrest and potentiates apoptosis in human gastric cancer cells in vitro through the NF-κB signaling pathway.

CHUK NFKBIA

7.53e-053175226520440
Pubmed

I kappa B alpha promoter polymorphisms in patients with systemic lupus erythematosus.

CHUK NFKBIA

7.53e-053175218071880
Pubmed

ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly.

ATAD3B ATAD3A

7.53e-053175234936866
Pubmed

Insulin-induced gene 1 (INSIG1) inhibits HIV-1 production by degrading Gag via activity of the ubiquitin ligase TRC8.

SCAP RNF139

7.53e-053175230563842
Pubmed

Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3.

ATAD3B ATAD3A

7.53e-053175225375035
Pubmed

Prostaglandin E2 protects lower airways against bronchoconstriction.

PTGER2 HPGD

7.53e-053175216113047
Pubmed

Analysis of cultured human melanocytes based on polymorphisms within the SLC45A2/MATP, SLC24A5/NCKX5, and OCA2/P loci.

SLC24A5 OCA2

7.53e-053175218650849
Pubmed

The catalytic subunits of IkappaB kinase, IKK-1 and IKK-2, contain non-equivalent active sites when expressed as homodimers.

CHUK NFKBIA

7.53e-053175212054687
Pubmed

Contributions in astrocytes of SMIT1/2 and HMIT to myo-inositol uptake at different concentrations and pH.

SLC5A3 SLC5A11

7.53e-053175222564531
Pubmed

Mapping quantitative trait loci for hearing loss in Black Swiss mice.

CDH23 PCDH15

7.53e-053175216426780
Pubmed

[ATAD3, a vital membrane-bound mitochondrial ATPase involved in tumor progression].

ATAD3B ATAD3A

7.53e-053175222192748
Pubmed

Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%.

CDH23 PCDH15

7.53e-053175216679490
Pubmed

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

CHUK NFKBIA

7.53e-053175211313968
Pubmed

Sebox plays an important role during the early mouse oogenesis in vitro.

SOHLH2 SEBOX

7.53e-053175222805237
Pubmed

Molecular cloning and functional expression of the K-Cl cotransporter from rabbit, rat, and human. A new member of the cation-chloride cotransporter family.

SLC12A2 SLC12A4

7.53e-05317528663127
Pubmed

Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane.

SLC5A7 SLC5A1

7.53e-053175215090548
Pubmed

Native American genetic ancestry and pigmentation allele contributions to skin color in a Caribbean population.

SLC24A5 OCA2

7.53e-053175237294081
Pubmed

Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart.

SLC5A1 SLC5A3

7.53e-053175228128227
Pubmed

Photoreceptor expression of the Usher syndrome type 1 protein protocadherin 15 (USH1F) and its interaction with the scaffold protein harmonin (USH1C).

CDH23 PCDH15

7.53e-053175215928608
Pubmed

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway.

CHUK NFKBIA

7.53e-053175211278366
Pubmed

The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study.

ERLIN1 CHUK

7.53e-053175223477746
Pubmed

Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members.

CDH23 PCDH15

7.53e-053175220498078
Pubmed

Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.

CHUK NFKBIA

7.53e-053175215856023
Pubmed

Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.

CDH23 PCDH15

7.53e-053175217805295
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

VPS13C MARCHF6 ERMP1 WDR43 TAOK2 SLC38A2 INTS5 TRANK1 SF3B3 DIXDC1 DOCK6

8.30e-055291751114621295
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

POMT2 PIGN MARCHF6 SLC35B2 ERMP1 ERLIN1 PTK7 HSPA13 SLC38A2 SCAP SLC12A2 CD47 CPSF1 UBIAD1 APOL2 PIGO SORL1

1.28e-0412011751735696571
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

CCNL2 COX15 SLC35B2 ZSWIM6 COQ2 WDR43 SLC38A2 NBAS SCAP SF3B3 SLC12A4 ATAD3A FBXO42 TMEM147 CPSF1 MTO1 ATP1A3 RNF139

1.37e-0413271751832694731
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC5A1 SLC5A3 SLC38A2 SLCO1C1

1.39e-0452175426590417
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

AMFR TMEM199 ATL3 ELOVL2 ERLIN1 TAOK2 NBAS ATAD3A

1.46e-04299175837931956
Pubmed

Ozonized low density lipoprotein (ozLDL) inhibits NF-kappaB and IRAK-1-associated signaling.

CHUK NFKBIA

1.50e-044175217053167
Pubmed

Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells.

CDH23 PCDH15

1.50e-044175216481439
Pubmed

Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis.

ATAD3B ATAD3A

1.50e-044175236736924
Pubmed

New role of IKK alpha/beta phosphorylated I kappa B alpha in axon outgrowth and axon initial segment development.

CHUK NFKBIA

1.50e-044175218321726
Pubmed

Control of stereocilia length during development of hair bundles.

CDH23 PCDH15

1.50e-044175237011103
Pubmed

Candidate gene acting as a suppressor of the RH locus in most cases of Rh-deficiency.

ICAM4 CD47

1.50e-04417528563755
Pubmed

GABAA-receptor alpha-subunit is an essential prerequisite for receptor formation in vivo.

OCA2 GABRA5

1.50e-04417529330366
Pubmed

The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy.

ATAD3B ATAD3A

1.50e-044175238250153
Pubmed

Activation of IKK/NF-κB provokes renal inflammatory responses in guanylyl cyclase/natriuretic peptide receptor-A gene-knockout mice.

CHUK NFKBIA

1.50e-044175222318993
Pubmed

Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination.

CHUK NFKBIA

1.50e-044175221862596
Pubmed

Aberrant NF-kappaB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts.

CHUK NFKBIA

1.50e-044175215782119
Pubmed

Identification and characterization of an IkappaB kinase.

CHUK NFKBIA

1.50e-04417529244310
Pubmed

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

CHUK NFKBIA

1.50e-044175212138192
Pubmed

A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus.

OCA2 GABRA5

1.50e-04417528392662
Pubmed

GPI7 is the second partner of PIG-F and involved in modification of glycosylphosphatidylinositol.

PIGN PIGO

1.50e-044175215632136
Pubmed

The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage.

SCAP RNF139

1.50e-044175219706601
Pubmed

A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization.

CHUK NFKBIA

1.50e-04417528246997
Pubmed

A NIK-IKKα module expands ErbB2-induced tumor-initiating cells by stimulating nuclear export of p27/Kip1.

CHUK NFKBIA

1.50e-044175223602409
InteractionFPR2 interactions

PIGN ATL3 SLC35B2 ERMP1 TTYH3 ELOVL2 SLC5A3 SLC35F2 MFSD8 ATP1A3 PIGO

9.06e-0913815411int:FPR2
InteractionLPAR1 interactions

SLC35B2 ERMP1 TTYH3 ELOVL2 SLC5A3 SCAP TMEM87B FAM210B CD47 SLC35F2 MFSD8 PIGO

7.84e-0821015412int:LPAR1
InteractionMS4A15 interactions

POMT2 AMFR MARCHF6 SLC12A2 SLC12A4 PIGO

4.78e-07391546int:MS4A15
InteractionHCST interactions

PIGN STK17B TNPO2 ATL3 ERMP1 TTYH3 INTS5 FAM210B UBE3C ATP1A3 D2HGDH

5.21e-0720515411int:HCST
InteractionTTYH1 interactions

POMT2 PIGN TMEM175 ERMP1 SLC5A3 SCAP SLC12A2 ABCB10 SLC12A4 FAM210B SLC35F2 CHST7 PIGO

5.45e-0730015413int:TTYH1
InteractionHTR3A interactions

POMT2 MARCHF6 OCA2 ERMP1 SCAP SLC12A2 APOL2 PIGO

1.79e-061081548int:HTR3A
InteractionGPR21 interactions

PIGN MARCHF6 ERMP1 ELOVL2 SCAP SLC12A4 MFSD8

2.87e-06811547int:GPR21
InteractionVIPR1 interactions

TRPM6 ATL3 COX15 ERMP1 TTYH3 TMEM87B CD47 SLC35F2 UBE3C PIGO

4.10e-0620515410int:VIPR1
InteractionGPR88 interactions

MARCHF6 SLC5A3 MFSD8 ATP1A3

5.56e-06161544int:GPR88
InteractionTSPAN15 interactions

PIGN COX15 GCGR SLC35B2 ERMP1 SCAP FAM210B CD47 SLC35F2 MFSD8 ATP1A3

9.28e-0627615411int:TSPAN15
InteractionGPR17 interactions

STK17B TNPO2 ATL3 ERMP1 TTYH3 ELOVL2 SLC5A3 NBAS INTS5 MFSD8 ATP1A3

1.17e-0528315411int:GPR17
InteractionCNGA4 interactions

POMT2 AMFR ERMP1 SLC12A2 PIGO

1.29e-05401545int:CNGA4
InteractionVIPR2 interactions

PIGN TNPO2 COX15 ERMP1 ELOVL2 SLC5A3 SLC35F2 ATP1A3 PIGO

1.88e-051941549int:VIPR2
InteractionGCGR interactions

PIGN ATL3 GCGR RDH13 ELOVL2 SLC5A3 ATP1A3

2.19e-051101547int:GCGR
InteractionZDHHC12 interactions

AMFR ERMP1 NBAS SCAP SLC12A2 SLC12A4 PIGO

4.49e-051231547int:ZDHHC12
InteractionOR4N2 interactions

AMFR SLC5A3 SLC12A4 PIGO

6.71e-05291544int:OR4N2
InteractionGPR12 interactions

ATL3 MFSD4B SLC5A3 ATP1A3 APOL2 SLC2A12

7.96e-05931546int:GPR12
InteractionBSCL2 interactions

ATP6V0C SLC35B2 ERMP1 TAOK2 CD47 SLC35F2 MFSD8 ASIC4

9.38e-051861548int:BSCL2
InteractionLAMP3 interactions

VPS13C TMEM199 ATL3 ELOVL2 SLC5A3 SLC38A2 INTS5 SLC12A2 SLC12A4 SLC35F2 MFSD8 UBIAD1 SLC26A11

9.47e-0548615413int:LAMP3
InteractionRNF170 interactions

AMFR GCGR SLC35B2 ERLIN1 ABCB10

1.11e-04621545int:RNF170
InteractionLINC02870 interactions

PLEKHG4 TRO VPS13C

1.18e-04131543int:LINC02870
InteractionCACNG6 interactions

SLC35B2 TTYH3 SLC5A3 SLC35F2

1.27e-04341544int:CACNG6
InteractionLPAR6 interactions

STK17B TNPO2 ATL3 SLC5A3 SLC38A2

1.73e-04681545int:LPAR6
InteractionATP1B4 interactions

POMT2 ERMP1 PTK7 SCAP ATP1A3

1.73e-04681545int:ATP1B4
InteractionGPR182 interactions

AMFR PLEKHG4 ATL3 COX15 SLC35B2 ERMP1 SLC5A3 INTS5 SLC35F2 UBE3C ATP1A3 PIGO

2.02e-0445515412int:GPR182
Cytoband11p15.4

OR52L2P OR51M1 OR52D1 OR52W1 OR52M1 OR52Z1P OR51H1

1.32e-05200176711p15.4
GeneFamilySolute carriers

SLC24A5 SLC22A25 SLC7A13 SLC37A3 SLC26A5 SLC5A7 SLC10A3 SLC35B2 SLC9C2 SLC40A1 SLC5A1 SLC5A3 SLC5A11 SLC2A10 SLC38A2 SLC7A4 SLC9A4 SLC12A2 SLCO1C1 SLC12A4 SLC15A5 SLC35F2 SLC26A11 SLC2A12 SLC16A8 SLC38A8

4.70e-1839512926752
GeneFamilyOlfactory receptors, family 52

OR52L2P OR52D1 OR52W1 OR52M1 OR52Z1P

2.54e-05491295165
GeneFamilyImmunoglobulin like domain containing

ICAM4 IL1RL2 PTK7 HEPACAM CD47 ADGRF5 IGLON5

4.73e-041931297594
CoexpressionGSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

AMFR LRRK2 TMEM175 ATL3 SLC12A2 GFOD1 PLA2G4F CPLANE1 TRAPPC6A

6.70e-062001709M9166
DiseaseUsher syndrome, type 1D

CDH23 PCDH15

2.78e-0521562C2931208
DiseaseUSHER SYNDROME, TYPE ID

CDH23 PCDH15

2.78e-0521562C1832845
DiseaseUSHER SYNDROME, TYPE ID

CDH23 PCDH15

2.78e-0521562601067
DiseaseUsher syndrome type 1D

CDH23 PCDH15

2.78e-0521562cv:C1832845
DiseaseUsher syndrome type 1D (is_implicated_in)

CDH23 PCDH15

2.78e-0521562DOID:0110831 (is_implicated_in)
Diseaseadhesion G protein-coupled receptor F5 measurement

RHCE ADGRF5

8.30e-0531562EFO_0801346
DiseaseDeaf Mutism

SLC26A5 PCDH15 SERAC1

1.55e-04201563C4082305
DiseaseDeafness, Acquired

SLC26A5 PCDH15 SERAC1

1.55e-04201563C0751068
DiseaseHearing Loss, Extreme

SLC26A5 PCDH15 SERAC1

1.55e-04201563C0086395
DiseaseComplete Hearing Loss

SLC26A5 PCDH15 SERAC1

1.55e-04201563C0581883
DiseaseBilateral Deafness

SLC26A5 PCDH15 SERAC1

1.55e-04201563C3665473
DiseasePrelingual Deafness

SLC26A5 PCDH15 SERAC1

1.55e-04201563C0011052
Diseaseneuromuscular disease (implicated_via_orthology)

ATAD3B ATAD3A

1.65e-0441562DOID:440 (implicated_via_orthology)
Diseaseinterleukin 1 receptor antagonist measurement

OCA2 TRANK1 UBE3C SLC26A11

1.80e-04531564EFO_0004754
DiseaseUsher syndrome, type 1A

CDH23 PCDH15

2.75e-0451562C2931205
DiseaseUSHER SYNDROME, TYPE IB (disorder)

CDH23 PCDH15

2.75e-0451562C1848638
DiseaseUSHER SYNDROME, TYPE IA, FORMERLY

CDH23 PCDH15

2.75e-0451562C1848639
DiseaseUSHER SYNDROME, TYPE I, FRENCH VARIETY, FORMERLY

CDH23 PCDH15

2.75e-0451562C1848640
DiseaseUsher syndrome type 1

CDH23 PCDH15

2.75e-0451562cv:C1568247
DiseaseDeafness

SLC26A5 PCDH15 SERAC1

3.06e-04251563C0011053
DiseaseUsher Syndrome, Type I

CDH23 PCDH15

4.11e-0461562C1568247
DiseaseManic Disorder

SLC5A3 TRANK1 CD47 DIXDC1

5.55e-04711564C0024713
DiseaseHereditary retinal dystrophy

CDH23 PCDH15

5.73e-0471562C0154860
DiseaseUsher syndrome

CDH23 PCDH15

5.73e-0471562cv:C0271097
DiseaseAlbinism, Oculocutaneous

SLC24A5 OCA2

5.73e-0471562C0078918
DiseaseManic

SLC5A3 TRANK1 CD47 DIXDC1

7.91e-04781564C0338831
DiseaseDepression, Bipolar

SLC5A3 TRANK1 CD47 DIXDC1

8.30e-04791564C0005587
DiseaseDisorder of eye

SLC24A5 CDH23 OCA2 PCDH15 MFSD8 CPLANE1

9.52e-042121566C0015397
Diseaserespiratory system disease

GSDMB ERMP1 SLC9A4 NFKBIA D2HGDH

1.06e-031451565EFO_0000684
Diseasehair colour measurement, eye colour measurement, skin pigmentation measurement

SLC24A5 OCA2

1.22e-03101562EFO_0007009, EFO_0007822, EFO_0009764
Diseaseeye color

SLC24A5 OCA2 TRANK1 TSPAN10

1.35e-03901564EFO_0003949
Diseaseinterleukin 1 receptor-like 1 measurement

IL1RL2 SLC9A4

1.48e-03111562EFO_0008168
Diseaseserum ST2 measurement

IL1RL2 SLC9A4

1.48e-03111562EFO_0005416
Diseaseejection fraction measurement

PTGER2 SLC5A11 HMCN1

1.53e-03431563EFO_0005527
Diseasetrimethylamine-N-oxide measurement

TAS1R2 UBE3C

2.42e-03141562EFO_0010541
Diseaseglucose-dependent insulinotropic peptide measurement, glucose tolerance test

SLC5A1 BTNL3

2.42e-03141562EFO_0004307, EFO_0008464
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

SLC26A5 CDH23 PCDH15

2.51e-03511563cv:CN043650
Diseaseinterleukin 18 receptor 1 measurement

IL1RL2 SLC9A4

2.79e-03151562EFO_0008178
Diseasemetabolite measurement

SLC24A5 PKD1L2 MFSD4B ELOVL2 SLC38A2 NBAS RNPEP NAPRT SORL1

3.05e-035601569EFO_0004725
Diseasedepressive disorder (is_implicated_in)

SLC5A7 GABRA5

3.59e-03171562DOID:1596 (is_implicated_in)
DiseaseDystonia, Limb

SERAC1 ATP1A3

3.59e-03171562C0751093
DiseaseDystonia, Diurnal

SERAC1 ATP1A3

3.59e-03171562C0393610
Diseaseadult onset asthma

ERMP1 IL1RL2 SLC9A4 D2HGDH

3.62e-031181564EFO_1002011
Diseasesyndrome (implicated_via_orthology)

ATAD3B ATAD3A

4.02e-03181562DOID:225 (implicated_via_orthology)
DiseaseDystonia, Paroxysmal

SERAC1 ATP1A3

4.02e-03181562C0393588
Diseaseage at onset, Parkinson disease

TMEM175 OCA2

4.02e-03181562EFO_0004847, MONDO_0005180
Diseaseatopic asthma

GSDMB ERMP1 IL1RL2 SLC9A4 D2HGDH

4.21e-031991565EFO_0010638
DiseaseSarcomatoid Renal Cell Carcinoma

CRADD LRRK2 SLC5A3 RNF139

4.83e-031281564C1266043
DiseaseChromophobe Renal Cell Carcinoma

CRADD LRRK2 SLC5A3 RNF139

4.83e-031281564C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

CRADD LRRK2 SLC5A3 RNF139

4.83e-031281564C1266044
DiseasePapillary Renal Cell Carcinoma

CRADD LRRK2 SLC5A3 RNF139

4.83e-031281564C1306837
DiseaseRenal Cell Carcinoma

CRADD LRRK2 SLC5A3 RNF139

4.83e-031281564C0007134

Protein segments in the cluster

PeptideGeneStartEntry
VAALGSLPLISIVGY

BTNL3

131

Q6UXE8
GILLLLDVVSLAYES

APOL2

281

Q9BQE5
IQTGLLYLAGERLLS

CDRT15L2

191

A8MXV6
VVLSLLILGSGHYAA

AREG

11

P15514
IPSYLIALAIGDLVS

RNPEP

226

Q9H4A4
VLSLFDGIATGLLVL

DNMT3A

636

Q9Y6K1
IASVEEGLILLLYGA

TBC1D32

556

Q96NH3
NSLISILGLAYVAGI

ADAM21

301

Q9UKJ8
TATVAGLTLLAVGVY

ATAD3A

296

Q9NVI7
LAYLIEIVAGEKLSG

DIXDC1

56

Q155Q3
AAVVGLVAVLLYASI

ERLIN1

11

O75477
ALYVVVSILLELAEG

GSDMB

396

Q8TAX9
ATGLSGNLIVLSVLY

ABCB10

401

Q9NRK6
SAVELTLIGYLLITA

FAM187A

376

A6NFU0
LAIAAGAYILVSTVL

SLC7A4

276

O43246
LGSDIYLDGIITIVD

CBWD5

156

Q5RIA9
LVLLGTSVLEGHVAY

CC2D2B

1201

Q6DHV5
LDYISGVLTLNGLLD

CDH23

286

Q9H251
TGLSEVRAALGLALY

ERMP1

66

Q7Z2K6
LYSVLGSILGQLAVI

ATP2C2

876

O75185
VTIATAILAGVYALI

OCA2

331

Q04671
TAAVSGLLVGYELGI

SLC2A12

46

Q8TD20
LLGLGSLVLILSLSY

SLC2A12

116

Q8TD20
VLYNGIILAALGVEA

MFSD8

306

Q8NHS3
TRLLELYLTAGVLTG

SLC16A8

106

O95907
AYLVLGALLVARLEG

KCNK6

16

Q9Y257
YGLTVALLSTGLDIV

OR52Z1P

181

P0C646
GATLVVYKDLLVLFG

FBXO42

176

Q6P3S6
GLDSILIAISYGFIL

OR52D1

211

Q9H346
SIALGAGSLLLVITY

COQ2

181

Q96H96
ILSFLGVSLVYGLII

OR10W1

16

Q8NGF6
ILGITGSYGLIAHAV

OR52W1

216

Q6IF63
AILGVSLLTLVGYLL

MUC15

246

Q8N387
LVEVNSGSLYGLTAL

LRIG1

271

Q96JA1
VSLYEAGITVGILLS

SLC2A10

136

O95528
YIGVLIDDLTTLGTS

MTO1

471

Q9Y2Z2
ILSLLSDIGSGIRYL

CHUK

121

O15111
LGSDIYLDGIITIVD

CBWD2

156

Q8IUF1
LGSDIYLDGIITIVD

CBWD1

156

Q9BRT8
VISLKGGEIYVLTLI

CPSF1

336

Q10570
AIFSLGLGESLYILV

LTK

146

P29376
FLLLGVGVTRYLAIA

GPR27

111

Q9NS67
LGSLAVGSLLYLVAR

HS3ST5

16

Q8IZT8
LLAALIGLYLVAGAT

KCNK12

41

Q9HB15
YILILNTVIGIASGE

OR51B2

216

Q9Y5P1
LYTLTLLGNGTILAV

OR51H1

36

Q8NH63
IALSYGLILHTVAGL

OR51M1

226

Q9H341
LAYVTTIGGTLSILA

OR3A4P

36

P47883
YLFSLLLGGDVTLAI

SLC10A3

271

P09131
SGGLAVLPVIYAVSL

PTGER2

151

P43116
VAVLGHSLGAYILTL

PDXDC2P

91

Q6P474
YGTVGVSLHIGISLI

FAM210B

96

Q96KR6
TVGYSLSLGALLLAL

GCGR

146

P47871
LLLYDILTTGGRIVE

LRRK2

2061

Q5S007
EGLITTIVGYILLAI

MARCHF6

331

O60337
ITIFTRILDGLLDGY

GABRA5

46

P31644
YVTGELGLALVLVLN

GNL1

211

P36915
SIHGYLGIVELLVSL

NFKBIA

191

P25963
VGILLLYLAVGVSVF

KCNS1

376

Q96KK3
IGASILTLLEILDYI

ASIC4

451

Q96FT7
YAIEAIKLGSTAIGI

PSMA5

26

P28066
LLLLLGVAALTTGYA

NRSN2

71

Q9GZP1
ITYITELSILGTVGV

PARP4

731

Q9UKK3
ILLLVALSVAYAAPG

CLPS

6

P04118
LAGLQELGLLDTVTY

PLA2G4F

376

Q68DD2
ELGLLDTVTYLSGVS

PLA2G4F

381

Q68DD2
LTYILTLAGNGLIIA

OR6X1

31

Q8NH79
IGDLSYAIAGLIFLE

NBAS

176

A2RRP1
VLYTSLGASIATGIL

MFSD4B

386

Q5TF39
LGTVAGAAVLLKDYV

RDH13

11

Q8NBN7
TGVTYTVLLGDITLA

PKD1L2

381

Q7Z442
DGSLLLDIVVSGYVL

HMCN1

4981

Q96RW7
YVASLLGNGLIVAAI

OR1K1

36

Q8NGR3
LGLTTLVSLSGSIIY

OTOP2

336

Q7RTS6
IVYALAFGLLVGLSV

GPR149

196

Q86SP6
LLVNIGSGVSILAVY

PANK2

386

Q9BZ23
AYLIGGLIALVAVAV

IL1RL2

336

Q9HB29
GYTEGALLALAFIII

PCDH15

1371

Q96QU1
ITAVSYGLIVLAVLS

OR6S1

216

Q8NH40
LYVLGSVLALFGVVL

G0S2

26

P27469
SGLSLVVGLVLYISS

CACNG5

141

Q9UF02
SILITEVGLGDEGLY

IGLON5

96

A6NGN9
YGSAIETLVTAISLI

CPSF6

441

Q16630
SVLGAVLKVVLYSLG

DOCK6

1411

Q96HP0
TVEYALELLFIGGLV

CPLANE1

1001

Q9H799
GILTLYNLGITLLSA

ELOVL2

66

Q9NXB9
LIGDRLYSGVLITLE

CCNL2

36

Q96S94
LGAEVLVEGLVLQYL

CRADD

16

P78560
LGSDIYLDGIITIVD

CBWD3

156

Q5JTY5
LGSDIYLDGIITIVD

CBWD6

156

Q4V339
SGLSLVVGLVLYISS

CACNG7

141

P62955
VLFTGIVALYIASGL

ATL3

446

Q6DD88
GALIFILTGYLTVTD

MS4A14

86

Q96JA4
LLVDIKDVILGLGYS

EPHX3

151

Q9H6B9
SGDNLYLGIVLAAVV

ATP1A3

116

P13637
LYIILSTGGIFLLVT

HEPACAM

241

Q14CZ8
TILGSAVLTLLLAGY

HSPA13

6

P48723
TLGLSLATAYGLLEL

DCST2

31

Q5T1A1
GLIVTSTGILILLHY

CD47

211

Q08722
LALAYTQVGLGISTL

COX15

361

Q7KZN9
IVGIYFGLVALISLS

DNAJC22

86

Q8N4W6
YGVFAILSGLVVLLL

SLC22A25

501

Q6T423
TGALLVKLVYLISDG

SLC15A5

481

A6NIM6
VTLYKVAALGLATGI

SCAP

706

Q12770
YGSLHGTVLGLEVVL

D2HGDH

216

Q8N465
LVAVVYAIGLIGSTI

OR8A1

161

Q8NGG7
YLLTVSGNGLIILTV

OR10G6

56

Q8NH81
SLGVTLYALVVVLGL

NOG

6

Q13253
IAALVGILLTVGAAY

ICAM4

246

Q14773
YGLTVALLVVGLDVL

OR52L2P

216

Q8NGH6
YGLSIGFLVLILDSV

OR52M1

201

Q8NGK5
INLVSVISGTYLGLD

HPGD

106

P15428
IVLQLTFGIGYVTLL

RNF139

131

Q8WU17
AVISSVAHYLGLGIL

RNF139

296

Q8WU17
IISALIATLYTLVGG

SLC5A7

166

Q9GZV3
LILLSLGVGFAILYT

SORL1

2146

Q92673
ILGGSLFLTYEVLAL

SERAC1

41

Q96JX3
IHVAGILSLLLGTAY

POMT2

701

Q9UKY4
LLFGLVGAEVSVSLL

SLC9B1P1

146

A6NJY1
QGGLLDLYLIAVTDL

TMEM121B

211

Q9BXQ6
GGLHSVGTYIIDLLT

GFOD1

171

Q9NXC2
GAVYQVLLVGSTLLK

PLEKHG4

276

Q58EX7
FLGLDYGLITAVIIA

SLC26A5

481

P58743
ALINALGIGLSLYLI

SLC9A4

166

Q6AI14
IILILEYAAGGEIFS

STK17B

106

O94768
LLTVTGGLVAVIYTD

SLC5A3

171

P53794
DLYLAIVGLLAITAV

SLC5A11

176

Q8WWX8
ALEVGLVGLGASYLL

TAOK2

991

Q9UL54
NSLLLTAVYGLVVAG

SLC40A1

56

Q9NP59
LGSLSDLIYALAIVV

SEBOX

171

Q9HB31
TQLYAGLVVSLSGLL

INTS5

536

Q6P9B9
LVFLISGLVILGYAA

SLC38A8

66

A6NNN8
LIGDILVLLGASLYA

SLC35F2

196

Q8IXU6
GAHLTVVIVFYGTLL

OR8K3

241

Q8NH51
LLYLAGVLAGSLTVS

RHBDL1

286

O75783
ISILSIYAGGIKSIF

SLC12A4

286

Q9UP95
SLLGILLDIISYVGV

ADGRF5

1006

Q8IZF2
LLDIISYVGVGFSIL

ADGRF5

1011

Q8IZF2
TYTGLSGLALLGTII

AMFR

16

Q9UKV5
VAGLTLLAVGVYSAK

ATAD3B

251

Q5T9A4
YTLVLLLVPSVLDGG

CHST7

21

Q9NS84
VDGLLSGILAIIYVS

TMEM269

111

A0A1B0GVZ9
AALIVASVVGLAELY

TMEM199

181

Q8N511
GLLLAAVPLGYVVSS

TMC8

541

Q8IU68
DGVYAIVATLLILDI

TMEM175

266

Q9BSA9
IFAEVLGLYGLIVAL

ATP6V0C

136

P27449
GALAITTGVLLLLAY

TMEM212

51

A6NML5
TLLSGYRITLIDIGL

TRPM6

501

Q9BX84
IFSLLGLLGEITYIV

RHCE

331

P18577
ALSLLLAVGSLIGYS

SLC37A3

361

Q8NCC5
TLLASYVFLGLGELL

SPNS3

366

Q6ZMD2
YILISTQESSAGILG

TRO

511

Q12816
GLVTGVLVLLSLDYL

SLC26A11

381

Q86WA9
ATTLSGLILLAGYIA

SLC35B2

266

Q8TB61
EAIYIILIAGELTIG

TAS2R9

6

Q9NYW1
TYSSILGTDILLLIV

SLC38A2

361

Q96QD8
LILYDAIGTLADSVG

TNPO2

536

O14787
GTLLAILITTLVYVG

SLC12A2

521

P55011
LGYLIAGIISLLAAV

SLCO1C1

276

Q9NYB5
IYLGLTVILGTVSIL

SLCO1C1

641

Q9NYB5
GGVDYQLLTLALLTV

TRIL

691

Q7L0X0
DIGISTILGSAIYNL

SLC24A5

136

Q71RS6
LGLATLSVLYELGII

SLC24A5

476

Q71RS6
GEAVVATLEGLYLLV

VPS13C

76

Q709C8
LAVALALGELGYRAV

NAPRT

301

Q6XQN6
GVVAGQALLLAEYSI

SLC7A13

106

Q8TCU3
KYVALGDLIILITFG

UBIAD1

181

Q9Y5Z9
GYLLAFTLGIEVLVL

PIGN

546

O95427
SLVYTTLSGGIGILV

SF3B3

1116

Q15393
SAYSGVLVTIVDLLV

TAS1R2

781

Q8TE23
LLRGALYTLGIESVV

TRAPPC6A

126

O75865
QGVLSATILYEILLG

TRB

276

P0DTU4
AAAVGLELAYVLVLG

ZDHHC24

26

Q6UX98
TLARLLVIIVSLGYG

TMEM87B

296

Q96K49
GYAIAVVLLQGAELL

TSPAN10

296

Q9H1Z9
SYLTLAVEVALIGLG

ZSWIM6

686

Q9HCJ5
LVGAIAYAGLLGTIE

PIGO

491

Q8TEQ8
HVGIELSYDILGSII

SLC9C2

216

Q5TAH2
LGLALVLTIYEAKGL

TRANK1

1556

O15050
AITALYTITGGLAAV

SLC5A1

186

P13866
ILLVGDVTVGYLADT

SOHLH2

21

Q9NX45
GLLALSTLALYVAVV

TMEM147

206

Q9BVK8
LQGLLETLLGYTAAI

TTYH3

171

Q9C0H2
GLSVGAAVAYIIAVL

PTK7

706

Q13308
GLSGTLILGALLVSY

ZP4

511

Q12836
GALSEEGLLVYLRVL

UBE3C

331

Q15386
LLALGTAVGSILLYS

WDR43

96

Q15061