Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	CTP synthase activity	CTPS2 CTPS1	1.01e-05	2	64	2	GO:0003883
GeneOntologyMolecularFunction	ceramide 1-phosphate binding	PLEKHA8P1 PLEKHA8	2.10e-04	7	64	2	GO:1902387
GeneOntologyMolecularFunction	ceramide 1-phosphate transfer activity	PLEKHA8P1 PLEKHA8	2.10e-04	7	64	2	GO:1902388
GeneOntologyMolecularFunction	ceramide transfer activity	PLEKHA8P1 PLEKHA8	2.80e-04	8	64	2	GO:0120017
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	IFNGR1 IGF2R PDGFRA OR4C16 OR4C6 NTRK2 IGHM GPR75 TLR5 OR8K3 GRPR LEPR OR4C5	3.05e-04	1353	64	13	GO:0004888
GeneOntologyMolecularFunction	microtubule severing ATPase activity	KATNAL2 KATNA1	3.59e-04	9	64	2	GO:0008568
GeneOntologyMolecularFunction	sphingolipid transfer activity	PLEKHA8P1 PLEKHA8	3.59e-04	9	64	2	GO:0120016
GeneOntologyMolecularFunction	protein-containing complex destabilizing activity	KATNAL2 KATNA1	1.03e-03	15	64	2	GO:0140776
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	IGF2R PDGFRA NTRK2	1.19e-03	65	64	3	GO:0004714
GeneOntologyMolecularFunction	growth factor binding	IGF2R PDGFRA NTRK2 FIBP	1.58e-03	156	64	4	GO:0019838
GeneOntologyMolecularFunction	sphingolipid transporter activity	PLEKHA8P1 PLEKHA8	1.85e-03	20	64	2	GO:0046624
GeneOntologyMolecularFunction	ceramide binding	PLEKHA8P1 PLEKHA8	1.85e-03	20	64	2	GO:0097001
GeneOntologyBiologicalProcess	'de novo' CTP biosynthetic process	CTPS2 CTPS1	9.48e-06	2	64	2	GO:0044210
GeneOntologyCellularComponent	cytoophidium	CTPS2 CTPS1	2.85e-05	3	65	2	GO:0097268
GeneOntologyCellularComponent	katanin complex	KATNAL2 KATNA1	9.46e-05	5	65	2	GO:0008352
GeneOntologyCellularComponent	sperm cytoplasmic droplet	ROPN1B ROPN1	9.46e-05	5	65	2	GO:0097598
MousePheno	increased birth weight	IGF2R LEPR	3.46e-05	3	48	2	MP:0009673
MousePheno	enlarged placenta	IGF2R PDGFRA LEPR	3.54e-05	19	48	3	MP:0004260
MousePheno	increased susceptibility to autoimmune diabetes	IGHM TLR5 LEPR	3.54e-05	19	48	3	MP:0004803
MousePheno	increased birth body size	IGF2R LEPR	6.90e-05	4	48	2	MP:0009702
MousePheno	pulmonary hyperplasia	IGF2R PDGFRA	1.15e-04	5	48	2	MP:0004202
Domain	CTP_synthase_N	CTPS2 CTPS1	1.16e-05	2	64	2	IPR017456
Domain	GATase1_CTP_Synthase	CTPS2 CTPS1	1.16e-05	2	64	2	IPR033828
Domain	CTP_synthase	CTPS2 CTPS1	1.16e-05	2	64	2	IPR004468
Domain	CTP_synth_N	CTPS2 CTPS1	1.16e-05	2	64	2	PF06418
Domain	Glycolipid_transfer_prot_dom	PLEKHA8P1 PLEKHA8	6.90e-05	4	64	2	IPR014830
Domain	GLTP	PLEKHA8P1 PLEKHA8	6.90e-05	4	64	2	PF08718
Domain	GATase	CTPS2 CTPS1	1.15e-04	5	64	2	PF00117
Domain	GATASE	CTPS2 CTPS1	1.72e-04	6	64	2	IPR017926
Domain	GATASE_TYPE_1	CTPS2 CTPS1	1.72e-04	6	64	2	PS51273
Domain	-	CTPS2 CTPS1	5.11e-04	10	64	2	3.40.50.880
Domain	Ephrin_rec_like	SCUBE2 SVEP1	6.23e-04	11	64	2	PF07699
Domain	Class_I_gatase-like	CTPS2 CTPS1	7.46e-04	12	64	2	IPR029062
Domain	cAMP_dep_PK_reg_su_I/II_a/b	ROPN1B ROPN1	1.18e-03	15	64	2	IPR003117
Domain	TIR	TLR5 TLR8	2.33e-03	21	64	2	SM00255
Domain	TIR	TLR5 TLR8	2.55e-03	22	64	2	PF01582
Domain	-	TLR5 TLR8	2.79e-03	23	64	2	3.40.50.10140
Domain	TIR	TLR5 TLR8	3.04e-03	24	64	2	PS50104
Domain	EGF_CA	FBN2 SCUBE2 SVEP1	3.21e-03	86	64	3	PF07645
Domain	Ephrin_rec_like	SCUBE2 SVEP1	3.30e-03	25	64	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	SCUBE2 SVEP1	3.30e-03	25	64	2	IPR011641
Domain	TIR_dom	TLR5 TLR8	3.30e-03	25	64	2	IPR000157
Domain	cEGF	FBN2 SCUBE2	3.56e-03	26	64	2	IPR026823
Domain	cEGF	FBN2 SCUBE2	3.56e-03	26	64	2	PF12662
Domain	Cys-rich_flank_reg_C	NTRK2 TLR5 TLR8	3.65e-03	90	64	3	IPR000483
Domain	LRRCT	NTRK2 TLR5 TLR8	3.65e-03	90	64	3	SM00082
Domain	hEGF	FBN2 SVEP1	4.13e-03	28	64	2	PF12661
Domain	EGF_Ca-bd_CS	FBN2 SCUBE2 SVEP1	4.50e-03	97	64	3	IPR018097
Domain	EGF_CA	FBN2 SCUBE2 SVEP1	4.76e-03	99	64	3	PS01187
Domain	ASX_HYDROXYL	FBN2 SCUBE2 SVEP1	4.90e-03	100	64	3	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN2 SCUBE2 SVEP1	5.76e-03	106	64	3	IPR000152
Domain	ARM-type_fold	TRPC4AP GBF1 PIK3CB SDAD1 ARMC8	6.08e-03	339	64	5	IPR016024
Domain	EGF_CA	FBN2 SCUBE2 SVEP1	8.48e-03	122	64	3	SM00179
Domain	EGF_3	FBN2 SCUBE2 ADAM23 SVEP1	8.61e-03	235	64	4	PS50026
Domain	EGF	FBN2 SCUBE2 ADAM23 SVEP1	8.61e-03	235	64	4	SM00181
Domain	EGF-like_Ca-bd_dom	FBN2 SCUBE2 SVEP1	8.86e-03	124	64	3	IPR001881
Pubmed	Cutting Edge: IFN-gamma-producing CD4 T lymphocytes mediate spore-induced immunity to capsulated Bacillus anthracis.	IFNGR1 IGHM	3.44e-06	2	65	2	17312104
Pubmed	Toll-like receptor 5 and 8 in hepatocellular carcinoma.	TLR5 TLR8	3.44e-06	2	65	2	33950532
Pubmed	Platelet derived growth factor-evoked Ca2+ wave and matrix gene expression through phospholipase C in human pulmonary fibroblast.	PDGFRA ITPR3	3.44e-06	2	65	2	23618877
Pubmed	Long peptide vaccination can lead to lethality through CD4+ T cell-mediated cytokine storm.	IFNGR1 IGHM	3.44e-06	2	65	2	20543102
Pubmed	Expression and Functionality Study of 9 Toll-Like Receptors in 33 Drug-Naïve Non-Affective First Episode Psychosis Individuals: A 3-Month Study.	TLR5 TLR8	3.44e-06	2	65	2	32854231
Pubmed	Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.	CTPS2 CTPS1	3.44e-06	2	65	2	20739275
Pubmed	Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.	CTPS2 CTPS1	1.03e-05	3	65	2	16179339
Pubmed	Loss of ASP but not ROPN1 reduces mammalian ciliary motility.	ROPN1B ROPN1	1.03e-05	3	65	2	22021175
Pubmed	Chromosomal mapping of the gene for the type II insulin-like growth factor receptor/cation-independent mannose 6-phosphate receptor in man and mouse.	IFNGR1 IGF2R	1.03e-05	3	65	2	2852162
Pubmed	Diabetes Induces Cardiac Fibroblast Activation, Promoting a Matrix-Preserving Nonmyofibroblast Phenotype, Without Stimulating Pericyte to Fibroblast Conversion.	PDGFRA LEPR	1.03e-05	3	65	2	36892073
Pubmed	Loss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrity.	ROPN1B ROPN1	1.03e-05	3	65	2	23303679
Pubmed	Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases.	IGHM TLR5	1.03e-05	3	65	2	31827095
Pubmed	Protein-tyrosine phosphatase 1B (PTP1B) is a novel regulator of central brain-derived neurotrophic factor and tropomyosin receptor kinase B (TrkB) signaling.	NTRK2 LEPR	1.03e-05	3	65	2	25288805
Pubmed	Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.	MUC5B LEPR	1.03e-05	3	65	2	20422702
Pubmed	T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance.	IFNGR1 IGHM	1.03e-05	3	65	2	23922396
Pubmed	Systematic dissection of coordinated stromal remodeling identifies Sox10+ glial cells as a therapeutic target in myelofibrosis.	PDGFRA LEPR	2.06e-05	4	65	2	37267917
Pubmed	Leptin rapidly improves glucose homeostasis in obese mice by increasing hypothalamic insulin sensitivity.	PIK3CB LEPR	2.06e-05	4	65	2	21123564
Pubmed	Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice.	IFNGR1 IGHM	2.06e-05	4	65	2	35696583
Pubmed	Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella.	ROPN1B ROPN1	2.06e-05	4	65	2	10591629
Pubmed	Negative impact of IFN-γ on early host immune responses to retroviral infection.	IFNGR1 IGHM	2.06e-05	4	65	2	22821964
Pubmed	Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.	PDGFRA LEPR	2.06e-05	4	65	2	35614212
Pubmed	Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis.	IFNGR1 TLR5	2.06e-05	4	65	2	26831100
Pubmed	Leptin is a physiological regulator of skeletal muscle angiogenesis and is locally produced by PDGFRα and PDGFRβ expressing perivascular cells.	PDGFRA LEPR	2.06e-05	4	65	2	30121753
Pubmed	FSCB phosphorylation regulates mouse spermatozoa capacitation through suppressing SUMOylation of ROPN1/ROPN1L.	ROPN1B ROPN1	2.06e-05	4	65	2	27398160
Pubmed	Elimination of Babesia microti Is Dependent on Intraerythrocytic Killing and CD4+ T Cells.	IFNGR1 IGHM	3.43e-05	5	65	2	28607116
Pubmed	Cutting Edge: IL-10 Is Essential for the Generation of Germinal Center B Cell Responses and Anti-Plasmodium Humoral Immunity.	IFNGR1 IGHM	3.43e-05	5	65	2	27940658
Pubmed	Regional specialization and fate specification of bone stromal cells in skeletal development.	PDGFRA LEPR	3.43e-05	5	65	2	34260921
Pubmed	CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.	ROPN1B ROPN1	3.43e-05	5	65	2	20731842
Pubmed	T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells.	IFNGR1 IGHM	3.43e-05	5	65	2	31076359
Pubmed	Synergistic roles of antibody and interferon in noncytolytic clearance of Sindbis virus from different regions of the central nervous system.	IFNGR1 IGHM	3.43e-05	5	65	2	17376910
Pubmed	PI3Kα inactivation in leptin receptor cells increases leptin sensitivity but disrupts growth and reproduction.	PIK3CB LEPR	3.43e-05	5	65	2	29212950
Pubmed	Importance of T cells, gamma interferon, and tumor necrosis factor in immune control of the rapid grower Mycobacterium abscessus in C57BL/6 mice.	IFNGR1 IGHM	3.43e-05	5	65	2	17875636
Pubmed	TLR agonists downregulate H2-O in CD8alpha- dendritic cells.	TLR5 TLR8	3.43e-05	5	65	2	21918198
Pubmed	Galectin-3 promotes the adipogenic differentiation of PDGFRα+ cells and ectopic fat formation in regenerating muscle.	PDGFRA LEPR	3.43e-05	5	65	2	35029658
Pubmed	PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion.	PDGFRA LEPR	3.43e-05	5	65	2	23776077
Pubmed	Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing.	KATNAL2 KATNA1	3.43e-05	5	65	2	26929214
Pubmed	Leptin-receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis.	PDGFRA LEPR	3.43e-05	5	65	2	28481328
Pubmed	Retrovirus-specificity of regulatory T cells is neither present nor required in preventing retrovirus-induced bone marrow immune pathology.	IFNGR1 IGHM	3.43e-05	5	65	2	19006695
Pubmed	Differences in serum cytokine levels between wild type mice and mice with a targeted mutation suggests necessity of using control littermates.	IFNGR1 IGHM	3.43e-05	5	65	2	22902947
Pubmed	Personal receptor repertoires: olfaction as a model.	OR4C16 OR8K3 OR4C5	5.02e-05	38	65	3	22908908
Pubmed	Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.	KATNAL2 KATNA1	5.13e-05	6	65	2	28436967
Pubmed	Increased a-series gangliosides positively regulate leptin/Ob receptor-mediated signals in hypothalamus of GD3 synthase-deficient mice.	IGHM LEPR	5.13e-05	6	65	2	27644882
Pubmed	Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice.	CTPS2 CTPS1	5.13e-05	6	65	2	38438357
Pubmed	Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA.	ROPN1B ROPN1	5.13e-05	6	65	2	11278869
Pubmed	Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis.	IFNGR1 LEPR	7.18e-05	7	65	2	34529935
Pubmed	Immunological correlates of protection mediated by a whole organism, Cryptococcus neoformans, vaccine deficient in chitosan.	IFNGR1 IGHM	7.18e-05	7	65	2	38980038
Pubmed	Multiplex screening of 22 single-nucleotide polymorphisms in 7 Toll-like receptors: an association study in rheumatoid arthritis.	TLR5 TLR8	7.18e-05	7	65	2	20194452
Pubmed	Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation.	IFNGR1 PDGFRA	7.18e-05	7	65	2	35139352
Pubmed	The bacterial microbiota regulates normal hematopoiesis via metabolite-induced type 1 interferon signaling.	IFNGR1 LEPR	7.18e-05	7	65	2	35143611
Pubmed	Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status.	IGF2R NTRK2	7.18e-05	7	65	2	20200945
Pubmed	IFN-γ receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity.	IFNGR1 IGHM	7.18e-05	7	65	2	27069112
Pubmed	Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.	LEPR ITPR3	7.18e-05	7	65	2	22495310
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	TPTE TRPC4AP GBF1 FBN2 SMCHD1 EIF2B3 DDX54 ARMC8 ITPR3	8.00e-05	974	65	9	28675297
Pubmed	Age-associated decrease in TLR function in primary human dendritic cells predicts influenza vaccine response.	TLR5 TLR8	9.56e-05	8	65	2	20100933
Pubmed	B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.	IFNGR1 IGHM	9.56e-05	8	65	2	27069113
Pubmed	A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2.	PDGFRA PIK3CB AHSA1	1.22e-04	51	65	3	26839216
Pubmed	Identification of a family of sorting nexin molecules and characterization of their association with receptors.	PDGFRA LEPR	1.23e-04	9	65	2	9819414
Pubmed	Polymorphism in 3'-untranslated region of toll-like receptor 4 gene is associated with protection from hepatitis B virus recurrence after liver transplantation.	TLR5 TLR8	1.23e-04	9	65	2	20977567
Pubmed	Regulation of angiogenesis, mural cell recruitment and adventitial macrophage behavior by Toll-like receptors.	TLR5 TLR8	1.23e-04	9	65	2	24091496
Pubmed	Sox2 in the dermal papilla regulates hair follicle pigmentation.	PDGFRA LEPR	1.23e-04	9	65	2	35858560
Pubmed	BDNF+/- mice exhibit deficits in oligodendrocyte lineage cells of the basal forebrain.	PDGFRA NTRK2	1.23e-04	9	65	2	20091777
Pubmed	B cell-intrinsic MyD88 signaling prevents the lethal dissemination of commensal bacteria during colonic damage.	IGHM TLR5	1.23e-04	9	65	2	22306056
Pubmed	FSCB, a novel protein kinase A-phosphorylated calcium-binding protein, is a CABYR-binding partner involved in late steps of fibrous sheath biogenesis.	ROPN1B ROPN1	1.23e-04	9	65	2	17855365
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	FBN2 IGF2R SMCHD1 EIF2B3 CTPS1 AHSA1 LEPR	1.47e-04	613	65	7	22268729
Pubmed	CTPS and IMPDH form cytoophidia in developmental thymocytes.	CTPS2 CTPS1	1.53e-04	10	65	2	34022203
Pubmed	[Expression of toll-like receptors in human epidermal keratinocytes].	TLR5 TLR8	1.53e-04	10	65	2	18686608
Pubmed	CFAP61 is required for sperm flagellum formation and male fertility in human and mouse.	ROPN1B ROPN1	1.53e-04	10	65	2	34792097
Pubmed	Daily Rhythms of TNFα Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle.	IFNGR1 IGHM	1.53e-04	10	65	2	29805094
Pubmed	Quantitative trait loci that determine plasma lipids and obesity in C57BL/6J and 129S1/SvImJ inbred mice.	IGF2R LEPR	1.53e-04	10	65	2	15210844
Pubmed	Polymorphisms in innate immunity genes associated with development of bronchiolitis obliterans after lung transplantation.	TLR5 TLR8	1.53e-04	10	65	2	20227302
Pubmed	Toll-like receptors.	TLR5 TLR8	1.53e-04	10	65	2	11782555
Pubmed	A family of human receptors structurally related to Drosophila Toll.	TLR5 TLR8	1.53e-04	10	65	2	9435236
Pubmed	B-1a lymphocytes promote oligodendrogenesis during brain development.	PDGFRA IGHM	1.53e-04	10	65	2	29507409
Pubmed	Toll-like receptors.	TLR5 TLR8	1.87e-04	11	65	2	18394314
Pubmed	Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner.	IGF2R LEPR	2.24e-04	12	65	2	17182038
Pubmed	PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation.	PLIN4 LEPR	2.24e-04	12	65	2	34079065
Pubmed	Mutation specific functions of EGFR result in a mutation-specific downstream pathway activation.	PIK3CB EIF2B3 DGKA	2.86e-04	68	65	3	25754235
Pubmed	Sequential autophosphorylation steps in the interleukin-1 receptor-associated kinase-1 regulate its availability as an adapter in interleukin-1 signaling.	TLR5 TLR8	3.08e-04	14	65	2	14625308
Pubmed	YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes.	TLR5 TLR8	3.08e-04	14	65	2	34206257
Pubmed	Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.	TLR5 TLR8	3.08e-04	14	65	2	20595247
Pubmed	Mast cells as sensors of cell injury through IL-33 recognition.	TLR5 TLR8	3.08e-04	14	65	2	21239713
Pubmed	Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity.	IFNGR1 IGHM	3.08e-04	14	65	2	25968334
Pubmed	A brain-to-spinal sensorimotor loop for repetitive self-grooming.	NTRK2 GRPR	3.56e-04	15	65	2	34932943
Pubmed	Common body mass index-associated variants confer risk of extreme obesity.	FBN2 ITPR3	3.56e-04	15	65	2	19553259
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	IFNGR1 GBF1 IGF2R DDX54 FAM114A2 SLC12A7 PLEKHA8P1 PLEKHA8	3.89e-04	952	65	8	38569033
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	GBF1 PIK3CB EIF2B3 ARMC8	3.91e-04	183	65	4	23956138
Pubmed	Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.	PDGFRA LEPR	4.06e-04	16	65	2	11279102
Pubmed	A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange.	PDGFRA NTRK2	4.06e-04	16	65	2	35714603
Pubmed	Expression of Toll-like receptors in the developing brain.	TLR5 TLR8	4.06e-04	16	65	2	22666391
Pubmed	Natural selection in the TLR-related genes in the course of primate evolution.	TLR5 TLR8	4.06e-04	16	65	2	18810425
Pubmed	A novel splice variant of interleukin-1 receptor (IL-1R)-associated kinase 1 plays a negative regulatory role in Toll/IL-1R-induced inflammatory signaling.	TLR5 TLR8	4.06e-04	16	65	2	16024789
Pubmed	Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.	TLR5 LEPR	4.59e-04	17	65	2	22297845
Pubmed	Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.	PLEKHA8P1 PLEKHA8	4.59e-04	17	65	2	11001876
Pubmed	Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development.	FBN2 PDGFRA SMCHD1 TFDP3	5.06e-04	196	65	4	19334288
Pubmed	Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth.	IGF2R LEPR	5.16e-04	18	65	2	23085235
Pubmed	Binding specificity of Toll-like receptor cytoplasmic domains.	TLR5 TLR8	5.76e-04	19	65	2	16482509
Pubmed	Toll-like receptor signaling pathway variants and prostate cancer mortality.	TLR5 TLR8	5.76e-04	19	65	2	19505919
Pubmed	A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1.	IFNGR1 TLR5	5.76e-04	19	65	2	34249474
Pubmed	TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects.	TLR5 TLR8	5.76e-04	19	65	2	28400473
Pubmed	Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo.	PDGFRA NTRK2	5.76e-04	19	65	2	28111199
Interaction	PLEKHA8P1 interactions	PLEKHA8P1 PLEKHA8	7.86e-06	2	57	2	int:PLEKHA8P1
Cytoband	3q21.1	ROPN1 PARP15	3.69e-04	20	65	2	3q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chrXp22	FANCB CTPS2 GRPR TLR8	4.48e-04	250	65	4	chrXp22
Cytoband	Xp22	CTPS2 TLR8	5.80e-04	25	65	2	Xp22
Cytoband	3q22.3	PIK3CB ARMC8	5.80e-04	25	65	2	3q22.3
Cytoband	Xp22.2	FANCB GRPR	1.49e-03	40	65	2	Xp22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11q11	OR4C16 OR4C6	1.49e-03	40	65	2	chr11q11
Cytoband	Ensembl 112 genes in cytogenetic band chr3q21	ROPN1B ROPN1 PARP15	1.55e-03	160	65	3	chr3q21
Cytoband	11q11	OR4C16 OR4C6	2.05e-03	47	65	2	11q11
Cytoband	1p34.1	EIF2B3 CTPS1	3.00e-03	57	65	2	1p34.1
GeneFamily	CD molecules\|Toll like receptors	TLR5 TLR8	2.81e-04	10	46	2	948
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	IFNGR1 IGF2R PDGFRA CRTAM TLR8 LEPR	4.62e-04	394	46	6	471
GeneFamily	Olfactory receptors, family 4	OR4C16 OR4C6 OR4C5	4.31e-03	129	46	3	151
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	PDGFRA NTRK2	4.64e-03	40	46	2	321
GeneFamily	AAA ATPases	KATNAL2 KATNA1	8.04e-03	53	46	2	413
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNGR1 IGF2R CRTAM DGKA SLC12A7	7.73e-06	186	65	5	4dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNGR1 IGF2R CRTAM DGKA SLC12A7	7.73e-06	186	65	5	e23e1246914e230369a716d0d666b98383bf8512
ToppCell	Fetal_29-31_weeks-Immune-B_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM23 SMCHD1 IGHM FAM111B PARP15	8.57e-06	190	65	5	424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCell	Fetal_29-31_weeks-Immune-B_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAM23 SMCHD1 IGHM FAM111B PARP15	8.79e-06	191	65	5	84452125d1b5b76974e3f9126f611eff16d45c25
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IGF2R SCUBE2 PDGFRA ARHGEF17 SVEP1	8.79e-06	191	65	5	e7c605b56934d1383237c1f946dbccef25d91368
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RPP25 ROPN1B ACSM6 BORCS7	5.10e-05	139	65	4	c9bf98bed77415a1438f3f9e441a1346e75c26b0
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	PDGFRA ADAM23 NTRK2 LEPR	1.02e-04	166	65	4	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PDGFRA ADAM23 NTRK2 LEPR	1.02e-04	166	65	4	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	RESF1 SMCHD1 IGHM PARP15	1.06e-04	168	65	4	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	COVID-19_Moderate-Treg\|World / disease group, cell group and cell class	RESF1 SMCHD1 DGKA SVEP1	1.09e-04	169	65	4	27ad11239559b025bef582f89b2a83501d9d3993
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	RPP25 PDGFRA LEPR SVEP1	1.09e-04	169	65	4	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TPTE PDGFRA SVEP1	1.11e-04	170	65	4	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IFNGR1 SCUBE2 PDGFRA CRTAM	1.22e-04	174	65	4	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-SMG_basal_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NTRK2 GPR75 ROPN1B ROPN1	1.27e-04	176	65	4	045b12c90f7dd49a9778dadcdf8f18125b380531
ToppCell	facs-Spleen-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFNGR1 CRTAM DGKA SLC12A7	1.30e-04	177	65	4	ac0cf03e2a1baf84db3ae245d59bbc6ae52c13be
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RPP25 FBN2 PDGFRA GRPR	1.33e-04	178	65	4	39889db130216655a34796e7030ffeb372465500
ToppCell	normal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RESF1 PHF3 SMCHD1 DGKA	1.33e-04	178	65	4	fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell-B_cell\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RESF1 SMCHD1 IGHM PARP15	1.36e-04	179	65	4	fad1fbee002fcd424c03460d695559060ce41a3f
ToppCell	droplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPP25 PCSK2 GPR75 ASB14	1.36e-04	179	65	4	4135f9e8cd8494cbc189e5210dded84659643fb8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RESF1 SMCHD1 IGHM PARP15	1.36e-04	179	65	4	6d4e4b64e633b2ae8514ffa1e45829d6508dac54
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell-B_cell-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RESF1 SMCHD1 IGHM PARP15	1.36e-04	179	65	4	61a7cc01fae4115325fce0efaa5bacf8f9af5ba2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RPP25 FBN2 GRPR SVEP1	1.42e-04	181	65	4	03a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IFNGR1 SCUBE2 PDGFRA SVEP1	1.42e-04	181	65	4	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IFNGR1 SCUBE2 PDGFRA SVEP1	1.45e-04	182	65	4	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 PDGFRA GRPR ITPR3	1.48e-04	183	65	4	f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	IFNGR1 SCUBE2 PDGFRA SVEP1	1.51e-04	184	65	4	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	PDGFRA NTRK2 LEPR SVEP1	1.51e-04	184	65	4	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA ADAM23 NTRK2 SVEP1	1.54e-04	185	65	4	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA ADAM23 NTRK2 SVEP1	1.54e-04	185	65	4	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA ADAM23 NTRK2 SVEP1	1.54e-04	185	65	4	a94694e226856bc5b168464f52d76004145717a5
ToppCell	facs-Skin-nan-24m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN4 PDGFRA LEPR SVEP1	1.54e-04	185	65	4	8433a337625ff8398520e223ef92bf9bb0beb14c
ToppCell	facs-Skin-nan-24m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN4 PDGFRA LEPR SVEP1	1.54e-04	185	65	4	049d793d043d5d434f143025de49dd210d18756c
ToppCell	facs-Skin-nan-24m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLIN4 PDGFRA LEPR SVEP1	1.54e-04	185	65	4	63200c42565eea596f9b00728e70e544b8d50a7f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FBN2 SCUBE2 PDGFRA GRPR	1.54e-04	185	65	4	6e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 PDGFRA NTRK2 SVEP1	1.54e-04	185	65	4	785c55d39909fac74415f24427979691e7e694e6
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 PDGFRA NTRK2 SVEP1	1.54e-04	185	65	4	97a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.57e-04	186	65	4	ca5e9c6531cb5d199e27509bfab1d62e3937177e
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RESF1 SMCHD1 IGHM PARP15	1.57e-04	186	65	4	1a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RESF1 SMCHD1 IGHM PARP15	1.57e-04	186	65	4	f1366638edaecad5cad6367440f4c693513bed7e
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.57e-04	186	65	4	1ed71b229f40a680071b14f5a7a19706e0fd14b1
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN2 PDGFRA NTRK2 SVEP1	1.57e-04	186	65	4	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 SMCHD1 IGHM PARP15	1.60e-04	187	65	4	8fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCell	Immune-B_cell\|World / Lineage, Cell type, age group and donor	ADAM23 SMCHD1 IGHM PARP15	1.60e-04	187	65	4	795690c6306c366e733279491138d0cd9b469b21
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 SMCHD1 IGHM PARP15	1.60e-04	187	65	4	edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.71e-04	190	65	4	00fd993675faf53adf985b9316a18c8a33242029
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 CRTAM DGKA PARP15	1.71e-04	190	65	4	ba61f04fd38efae01f721ba616252d1372ff1002
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 SMCHD1 DGKA PARP15	1.71e-04	190	65	4	b772a5d281fe016f259ddda80d6f33d949dcac2b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 CRTAM DGKA PARP15	1.71e-04	190	65	4	5a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCell	T_cells-Effector_memory_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	IFNGR1 RESF1 ADAM23 DGKA	1.71e-04	190	65	4	1af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.71e-04	190	65	4	8cda09d761c6b504a744959d587c183f94f1beeb
ToppCell	PCW_10-12-Immune_Lymphocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	IGHM CRTAM TRGV9 PARP15	1.71e-04	190	65	4	9b56763d62e1ed50006a5b90b160c5a82aab515b
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	PHF3 SMCHD1 USPL1 PARP15	1.74e-04	191	65	4	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 SMCHD1 DGKA PARP15	1.74e-04	191	65	4	1a2d5fec2bea96da2154b0aed252f1bb35102f6e
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.74e-04	191	65	4	c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.74e-04	191	65	4	243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCell	356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AREL1 GBF1 SLC12A7 PARP15	1.74e-04	191	65	4	2b427741a58921e161101a282d1fe526cd9e760d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RESF1 SMCHD1 DGKA PARP15	1.74e-04	191	65	4	326b4541069efedc8ab409f85bb11f77346dda90
ToppCell	droplet-Lung-30m-Mesenchymal\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SCUBE2 PDGFRA ARHGEF17 SVEP1	1.78e-04	192	65	4	5d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	1.81e-04	193	65	4	cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	1.81e-04	193	65	4	6ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	1.81e-04	193	65	4	e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IGF2R SCUBE2 PDGFRA SVEP1	1.85e-04	194	65	4	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRGV9 FAM114A2 TRAPPC9 FAM111B	1.85e-04	194	65	4	5031f324628ff12a33e84cc52157be4786e0961d
ToppCell	PCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	IGHM CRTAM TRGV9 PARP15	1.88e-04	195	65	4	4570644bcf8bbdfcd70f3cd8840eb94d3df383c8
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA ADAM23 LEPR SVEP1	1.88e-04	195	65	4	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	proximal-3-Hematologic-IGSF21+_Dendritic\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FANCB CRTAM DGKA SLC12A7	1.88e-04	195	65	4	8592d0332bc82a91e173680cfd1afc5ee189b289
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 GBF1 NTRK2 ARHGEF17	1.88e-04	195	65	4	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	proximal-Hematologic-IGSF21+_Dendritic\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FANCB CRTAM DGKA SLC12A7	1.88e-04	195	65	4	c48ff83c48342875f06c6c9e7d5bc6084a992848
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PHF3 SMCHD1 IGHM PARP15	1.88e-04	195	65	4	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	RESF1 PHF3 SMCHD1 DGKA	1.88e-04	195	65	4	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	proximal-Hematologic-IGSF21+_Dendritic-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FANCB CRTAM DGKA SLC12A7	1.88e-04	195	65	4	ae9d61011e95f7840cbb154738c79745fd29943e
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PHF3 SMCHD1 CRTAM AHSA1	1.92e-04	196	65	4	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IGF2R SCUBE2 PDGFRA SVEP1	1.92e-04	196	65	4	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RESF1 IGHM DGKA PARP15	1.92e-04	196	65	4	3a8bd09a09c19df27c954d448f1bae945314c221
ToppCell	COVID-19_Severe-PLT_4\|World / Disease Group and Platelet Clusters	IFNGR1 RESF1 PHF3 MOB4	1.92e-04	196	65	4	ad43efdd4d73b6615f65f06a315b33576e317473
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM23 TFDP3 LEPR FAM111B	1.92e-04	196	65	4	eb8c9a4a5eb21d43ff7b25deae5896c236f669b9
ToppCell	Biopsy_Other_PF-Immune-B_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	RESF1 SMCHD1 IGHM PARP15	1.92e-04	196	65	4	123cd893fd1ae315a655e909c08528f82e9013ff
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	RESF1 IGHM DGKA PARP15	1.96e-04	197	65	4	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	1.96e-04	197	65	4	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	1.96e-04	197	65	4	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	10x5'v1-week_14-16-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	IGHM DDX54 FAM111B PARP15	1.96e-04	197	65	4	78122e1fb80e0ac3084dd4f7c551996330a701df
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	IGF2R RESF1 SMCHD1 TLR8	1.96e-04	197	65	4	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	1.96e-04	197	65	4	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	Biopsy_IPF-Immune-B_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	RESF1 SMCHD1 IGHM PARP15	2.00e-04	198	65	4	6a519337a4932a7b685fe7defd3de24fa2016b7d
ToppCell	COVID-19_Severe-Neu_1\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	IGF2R RESF1 SMCHD1 TLR8	2.00e-04	198	65	4	bbe639ea5a636c985e509fb0a133ae3b60afac5a
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.00e-04	198	65	4	a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.00e-04	198	65	4	8b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.00e-04	198	65	4	4739b2e4ab141c66772e61686b45614a1839483e
ToppCell	stromal_cell\|World / Lineage and Cell class	PDGFRA NTRK2 LEPR SVEP1	2.04e-04	199	65	4	507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCell	stromal_cell-stromal_cell\|World / Lineage and Cell class	PDGFRA NTRK2 LEPR SVEP1	2.04e-04	199	65	4	74262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.04e-04	199	65	4	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.04e-04	199	65	4	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RESF1 PHF3 SMCHD1 DGKA	2.04e-04	199	65	4	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.04e-04	199	65	4	6200618e029063486719479c41eaf31798bd13cf
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PDGFRA NTRK2 LEPR SVEP1	2.04e-04	199	65	4	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PLIN4 ATP13A4 NTRK2 GPR75	2.08e-04	200	65	4	7a8160e6477708f22e48c609bf8f43f3715dcb03
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RESF1 CRTAM TRGV9 PARP15	2.08e-04	200	65	4	f7913fddd35932db5b5759995b0576350821bc22
ToppCell	mLN-T_cell-CD8_T\|T_cell / Region, Cell class and subclass	IFNGR1 IGHM CRTAM TRGV9	2.08e-04	200	65	4	650916c6d2bcf00315c7a21088cb63f37bf24346
Disease	Hyperphagia	NTRK2 LEPR	2.60e-05	4	62	2	C0020505
Disease	glucose metabolism disease (implicated_via_orthology)	PIK3CB TLR5 DGKA	2.79e-05	28	62	3	DOID:4194 (implicated_via_orthology)
Disease	chronic kidney disease (implicated_via_orthology)	PCSK2 LEPR	2.83e-04	12	62	2	DOID:784 (implicated_via_orthology)
Disease	Lewy Body Disease	IGF2R NTRK2	9.77e-04	22	62	2	C0752347
Disease	glucocorticoid receptor gene expression measurement	PLEKHA8P1 PLEKHA8	1.47e-03	27	62	2	EFO_0600079
Disease	arteriosclerosis (is_marker_for)	IFNGR1 LEPR	1.70e-03	29	62	2	DOID:2349 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TETGLLCATSKTIKL	ACSM6	371	Q6P461
SIRGVKDSKVALSTC	ADAM23	201	O75077
TCKITLKETFLTSPE	AHSA1	206	O95433
TINCITVALVFSKGK	ATP13A4	1046	Q4VNC1
TVIKDTKFCEVITLS	ASB14	471	A6NK59
TTGTTCSKAIKLFVE	MUC5B	946	Q9HC84
EGATKLVCDLITSTK	ITPR3	1731	Q14573
FTDLIVCTTLKRKSG	ARHGEF17	1311	Q96PE2
LKTVYKSGETIVVTC	PDGFRA	221	P16234
IIKKCLTTVEVLSFS	PARP15	186	Q460N3
LAKFTLGKCSTLIVT	DDX54	381	Q8TDD1
TLLAKAVATECKTTF	KATNAL2	301	Q8IYT4
SIFSTCKKLEESLTV	DGKA	566	P23743
SLLSTTDLEKGSVCI	LEPR	941	P48357
VGTLLKSTCNTFLKT	PLEKHA8	151	Q96JA3
LSTAKDSKAVVTCVI	GPR75	311	O95800
SLVVGVKTTSSLKLS	FANCB	486	Q8NB91
EKSSIKRSVIGSSCL	EIF2B3	366	Q9NR50
STELKTECAVVLGSL	ARMC8	76	Q8IUR7
FASIFLTKSTKLTCL	IGHM	231	P01871
LTKSTKLTCLVTDLT	IGHM	236	P01871
ETDGKKCNTTSTLII	CRTAM	171	O95727
IGNITLIKIFCTVKS	GRPR	56	P30550
SKTKIVCHFSTLVLT	AREL1	166	O15033
SVKGLLTEKVTTCGT	BORCS7	16	Q96B45
TIVLCKELSSLSKEF	FAM114A2	421	Q9NRY5
KELSSLSKEFTTCLT	FAM114A2	426	Q9NRY5
LSKEFTTCLTTAGVK	FAM114A2	431	Q9NRY5
TKSLLKCVESLSFIV	GBF1	1386	Q92538
TLLAKAVATECKTTF	KATNA1	256	O75449
SKLSSTGLICIDSLK	FBN2	881	P35556
GIRKCSSTFKLKSEV	FAM111B	46	Q6SJ93
EKTKGFCQLVVSSSL	SLC12A7	756	Q9Y666
TIRTSVTFKLNEGKC	SCUBE2	486	Q9NQ36
SKEVCITIFNSSIKG	IFNGR1	231	P15260
VDALLKKTTISFSEC	OR4C16	81	Q8NGL9
LLTEKKTISFSGCMT	OR4C5	106	Q8NGB2
VDTLSKSTTISLKGC	OR4C6	81	Q8NH72
KSTTISLKGCLTQLF	OR4C6	86	Q8NH72
GRATTKTVTCAEILK	RPP25	71	Q9BUL9
DDISTKTGITLKSCR	FIBP	121	O43427
KTASSVIELTCTKTV	IGF2R	2086	P11717
DTTKTVLTGTKDTVC	PLIN4	706	Q96Q06
GTLLKSTCNTFLKTL	PLEKHA8P1	36	O95397
ACSALGVTITKTLKI	ROPN1B	126	Q9BZX4
KFVITTTSRKEITCD	SMCHD1	71	A6NHR9
ICIKSGKISSLAVTF	PRUNE2	1376	Q8WUY3
LCKLATRKVSESTGT	TRPC4AP	301	Q8TEL6
VSIKESSVAKLGSVC	MOB4	146	Q9Y3A3
GFKCTERESISLTKL	RESF1	1586	Q9HCM1
KGIIASSVGTILKSC	CTPS1	16	P17812
STKTLSKTARLECVV	TRGV9	31	Q99603
VITTACFSKVTKILV	SDAD1	201	Q9NVU7
KCTSDTVFLEKTSKI	KDF1	261	Q8NAX2
TELLCKTIVSSEVSG	PIK3CB	361	P42338
KELTTEVGVVTFSCK	SVEP1	2336	Q4LDE5
SLLVTIKIFTLSFCG	OR8K3	156	Q8NH51
LTVEEGKSITLSCSV	NTRK2	206	Q16620
GKSIVSLELTTCVSD	TLR8	811	Q9NR97
KGIIASSIGTILKSC	CTPS2	16	Q9NRF8
VVFSTISLGKCSVLD	TPTE	441	P56180
LKNTVTGLCSKEESI	USPL1	251	Q5W0Q7
ISVCKTFIKSSLDIS	ZBTB8A	111	Q96BR9
ACSALGVTITKTLKI	ROPN1	126	Q9HAT0
SLLSETCVTIGEKKN	PHF3	256	Q92576
FIIISSSKKTVINCS	TFDP3	256	Q5H9I0
LCETGFSTLSVIKTK	ZBED9	1276	Q6R2W3
KVVGLITITDCFSAK	TRAPPC9	76	Q96Q05
KSLKFSLFIVCTVTL	TLR5	636	O60602
STGKLVLTLTTDACE	PCSK2	481	P16519