Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMHC class I receptor activity

LILRA1 LILRA3 LILRB2 LILRB1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4

1.06e-1418988GO:0032393
GeneOntologyMolecularFunctioninhibitory MHC class I receptor activity

LILRA1 LILRA3 LILRB2 LILRB1 KIR2DS5 KIR3DL1 LILRA4

4.28e-1412987GO:0032396
GeneOntologyMolecularFunctionMHC class Ib protein binding

LILRA1 LILRB2 LILRB1 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

6.09e-1316987GO:0023029
GeneOntologyMolecularFunctionimmune receptor activity

LILRA1 LILRA3 LILRB2 CR1 CR1L LILRB1 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4

1.52e-121659813GO:0140375
GeneOntologyMolecularFunctionMHC class Ib receptor activity

LILRA1 LILRB2 LILRB1 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.65e-1219987GO:0032394
GeneOntologyMolecularFunctionHLA-B specific inhibitory MHC class I receptor activity

LILRA1 LILRB2 LILRB1 KIR3DL1

8.12e-096984GO:0030109
GeneOntologyMolecularFunctionMHC protein binding

LILRA1 LILRB2 LILRB1 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

1.35e-0858987GO:0042287
GeneOntologyMolecularFunctionIgM binding

LILRA1 LILRB2 LILRB1 LILRA4

1.75e-0711984GO:0001791
GeneOntologyMolecularFunctionHLA-A specific inhibitory MHC class I receptor activity

LILRA1 LILRB2 LILRB1

1.14e-065983GO:0030107
GeneOntologyMolecularFunctionMHC class Ib protein complex binding

LILRA1 LILRB2 LILRB1

3.96e-067983GO:0023025
GeneOntologyMolecularFunctioncomplement component C3b receptor activity

CR1 CR1L

2.38e-052982GO:0004877
GeneOntologyMolecularFunctioncomplement component C4b receptor activity

CR1 CR1L

2.38e-052982GO:0001861
GeneOntologyMolecularFunctionimmunoglobulin binding

LILRA1 LILRB2 LILRB1 LILRA4

2.85e-0536984GO:0019865
GeneOntologyMolecularFunctioncomplement component C4b binding

CR1 CR1L

7.13e-053982GO:0001855
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

VN1R3 LILRA1 LILRA3 LILRB2 KIR2DS2 PTPRU CR1 CR1L LILRB1 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS1 KIR2DS5 OR5L2 KIR3DL1 KIR3DS1 LILRA4

9.24e-0513539818GO:0004888
GeneOntologyMolecularFunctioncoreceptor activity

LILRA1 LILRB2 LILRB1 LILRA4

4.35e-0472984GO:0015026
GeneOntologyMolecularFunctionMHC class I protein binding

LILRA1 LILRB2 LILRB1

5.13e-0432983GO:0042288
GeneOntologyMolecularFunctionopsonin receptor activity

CR1 CR1L

6.55e-048982GO:0001847
GeneOntologyMolecularFunctionprotein phosphatase 1 binding

LILRA1 LILRB2 LILRB1

6.69e-0435983GO:0008157
GeneOntologyMolecularFunctionMHC protein complex binding

LILRA1 LILRB2 LILRB1

1.07e-0341983GO:0023023
GeneOntologyMolecularFunctioncomplement component C3b binding

CR1 CR1L

1.52e-0312982GO:0001851
GeneOntologyMolecularFunctionamyloid-beta binding

LILRA1 LILRB2 LILRB1 KIR3DL1

1.60e-03102984GO:0001540
GeneOntologyMolecularFunctioncomplement receptor activity

CR1 CR1L

2.09e-0314982GO:0004875
GeneOntologyMolecularFunctionSH2 domain binding

LILRA1 LILRB2 LILRB1

2.13e-0352983GO:0042169
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FN1 OTOL1 SLIT2 LTBP2 MUC5AC

2.35e-03188985GO:0005201
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

DDO LOXL1

2.74e-0316982GO:0016641
GeneOntologyBiologicalProcessimmune response-regulating signaling pathway

LILRA1 LILRA3 LILRB2 RAPGEF1 KIR2DS2 CR1 LILRB1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LRRFIP2 LILRA4

4.53e-096159817GO:0002764
GeneOntologyBiologicalProcessregulation of immune response

LILRA1 LILRA3 LILRB2 MKRN2 RAPGEF1 KIR2DS2 CR1 CR1L LILRB1 KIR3DL3 KIR2DL1 KLK5 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LRRFIP2 LILRA4

1.51e-0710859820GO:0050776
GeneOntologyBiologicalProcessinterleukin-10-mediated signaling pathway

LILRA1 LILRA3 LILRB2 LILRB1

1.54e-0711984GO:0140105
GeneOntologyBiologicalProcessnegative regulation of hemopoiesis

LILRA1 LILRB2 IL17D CR1 LILRB1 TMEM131L LILRA4

1.09e-05159987GO:1903707
GeneOntologyBiologicalProcessimmune response-inhibiting cell surface receptor signaling pathway

LILRB2 LILRB1 KIR2DL1

1.22e-0510983GO:0002767
GeneOntologyBiologicalProcessimmune response-inhibiting signal transduction

LILRB2 LILRB1 KIR2DL1

2.22e-0512983GO:0002765
GeneOntologyBiologicalProcesspositive regulation of long-term synaptic depression

LILRA1 LILRB2 LILRB1

3.64e-0514983GO:1900454
GeneOntologyBiologicalProcessnegative regulation of immune system process

LILRA1 FN1 LILRB2 MKRN2 IL17D EPX CR1 CR1L LILRB1 SLIT2 TMEM131L LILRA4

4.46e-056319812GO:0002683
GeneOntologyBiologicalProcessnegative regulation of cell development

LILRA1 LILRB2 MBD1 IL17D CR1 LILRB1 SLIT2 TMEM131L LILRA4

4.69e-05353989GO:0010721
GeneOntologyBiologicalProcessnegative regulation of leukocyte differentiation

LILRA1 LILRB2 CR1 LILRB1 TMEM131L LILRA4

8.43e-05151986GO:1902106
GeneOntologyBiologicalProcessdefense response to nematode

ITLN1 EPX

1.33e-044982GO:0002215
GeneOntologyBiologicalProcessregulation of long-term synaptic depression

LILRA1 LILRB2 LILRB1

1.72e-0423983GO:1900452
GeneOntologyBiologicalProcessnegative regulation of osteoclast differentiation

LILRA1 LILRB2 LILRB1 LILRA4

1.78e-0459984GO:0045671
GeneOntologyBiologicalProcessregulation of cell development

VIM SETD1A LILRA1 FN1 LILRB2 MBD1 IL17D CR1 LILRB1 SLIT2 CLCN2 NCAN TMEM131L GNAS LILRA4

1.98e-0410959815GO:0060284
GeneOntologyBiologicalProcessFc receptor mediated inhibitory signaling pathway

LILRB2 LILRB1

2.21e-045982GO:0002774
GeneOntologyBiologicalProcessregulation of osteoclast differentiation

LILRA1 LILRB2 LILRB1 GNAS LILRA4

2.31e-04116985GO:0045670
GeneOntologyBiologicalProcessmyeloid dendritic cell differentiation

LILRA1 LILRB2 LILRB1

3.13e-0428983GO:0043011
GeneOntologyCellularComponentFc-epsilon receptor I complex

LILRA1 LILRB2 LILRB1 LILRA4

5.39e-089974GO:0032998
GeneOntologyCellularComponentFc receptor complex

LILRA1 LILRB2 LILRB1 LILRA4

2.10e-0712974GO:0032997
MousePhenodecreased length of allograft survival

LILRA1 LILRB2 LILRB1

1.12e-059733MP:0004752
MousePhenoenlarged stomach

ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

2.50e-0533734MP:0003883
MousePhenoabnormal visual cortex morphology

LILRA1 LILRB2 LILRB1

7.29e-0516733MP:0000805
MousePhenoabnormal occipital lobe morphology

LILRA1 LILRB2 LILRB1

1.05e-0418733MP:0000804
MousePhenoabnormal dendritic cell differentiation

LILRA1 LILRB2 LILRB1

1.46e-0420733MP:0008115
Domainig

LILRA1 LILRA3 KIR2DS2 LILRB1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

1.21e-121909814PF00047
DomainImmunoglobulin

LILRA1 LILRA3 KIR2DS2 LILRB1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

1.21e-121909814IPR013151
DomainIG

IGSF8 LILRA1 LILRA3 LILRB2 KIR2DS2 PTPRU LILRB1 NCAN KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

6.20e-124219818SM00409
DomainIg_sub

IGSF8 LILRA1 LILRA3 LILRB2 KIR2DS2 PTPRU LILRB1 NCAN KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

6.20e-124219818IPR003599
DomainIg-like_fold

IGSF8 LILRA1 LILRA3 FN1 MYCBP2 LILRB2 KIR2DS2 PTPRU LILRB1 NCAN KIR3DL3 FLRT1 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

8.21e-117069821IPR013783
DomainIG_LIKE

IGSF8 LILRA1 LILRA3 LILRB2 KIR2DS2 PTPRU LILRB1 NCAN KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 LILRA4 SEMA3E

6.68e-104919817PS50835
DomainIg-like_dom

IGSF8 LILRA1 LILRA3 LILRB2 KIR2DS2 PTPRU LILRB1 NCAN KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

9.64e-105039817IPR007110
Domain-

IGSF8 LILRA1 LILRA3 FN1 MYCBP2 KIR2DS2 PTPRU LILRB1 NCAN FLRT1 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1 LILRA4 SEMA3E

9.23e-0966398182.60.40.10
DomainA1B_glyco/leuk_Ig-like_rcpt

LILRA1 LILRA3 LILRA4

2.77e-066983IPR016332
DomainIg_2

LILRA1 LILRA3 LILRB1 LILRA4

5.88e-0473984PF13895
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

LILRA1 LILRA3 LILRB2 KIR2DS2 LILRB1 KIR2DL1 KIR2DL3 KIR2DS1 KIR3DL1 LILRA4

8.88e-081907810M8240
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

5.35e-0788787M16004
PathwayWP_SPINAL_CORD_INJURY

VIM LILRA1 LILRB2 LILRB1 SLIT2 NCAN

2.89e-05108786MM15954
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

7.52e-0541784M13519
PathwayKEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY

KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.09e-04137786M5669
PathwayREACTOME_DAP12_INTERACTIONS

KIR2DS2 KIR2DS1 KIR2DS5 KIR3DS1

1.19e-0446784M27151
PathwayREACTOME_DAP12_INTERACTIONS

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.22e-0454784MM14871
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.02e-2014101919875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

LILRA3 KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.02e-2014101919421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.02e-2014101915896204
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

5.03e-2015101920082646
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

5.03e-2015101919926642
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

5.03e-2015101920356536
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

5.03e-2015101920643584
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

5.03e-2015101919326408
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101919897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101919000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101920670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101919527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101920652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101918668235
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101919279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101917868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101918643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101919309280
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101920331834
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.15e-1916101920210919
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101920173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101920483367
Pubmed

[Effects of killer immunoglobulin-like receptor and human leukocyte antigen class I ligand on the prognosis of related donor hematopoietic stem cell transplantation].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101919968064
Pubmed

[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101919218127
Pubmed

KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101919169284
Pubmed

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101920878400
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101920650299
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101919450876
Pubmed

Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.43e-1917101919761533
Pubmed

Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1918101919630074
Pubmed

Influence of HLA class I and HLA-KIR compound genotypes on HIV-2 infection and markers of disease progression in a Manjako community in West Africa.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1918101920519398
Pubmed

Combination of KIR 2DL2 and HLA-C1 (Asn 80) confers susceptibility to type 1 diabetes in Latvians.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1918101919046302
Pubmed

Effect of killer immunoglobulin-like receptors in the response to combined treatment in patients with chronic hepatitis C virus infection.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1918101919846535
Pubmed

Association of killer cell immunoglobulin-like receptors and human leukocyte antigen-C genotypes in South Brazilian with type 1 diabetes.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1918101920580654
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.24e-1911101819664392
Pubmed

KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

9.19e-1919101918571006
Pubmed

Association between killer-cell immunoglobulin-like receptor genotypes and leprosy in Brazil.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

9.19e-1919101918778326
Pubmed

Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with solid tumors.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

9.19e-1919101920600442
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Southern Brazilian population from the state of ParanĂ¡.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

9.19e-1919101918848853
Pubmed

Compound KIR-HLA genotype analyses in the Iranian population by a novel PCR-SSP assay.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.67e-1820101920193031
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.87e-1812101820371502
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.87e-1812101819181658
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.87e-1812101819936734
Pubmed

Activating killer cell immunoglobulin-like receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.91e-1821101919861144
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1813101818687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1813101819934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.85e-1813101819120281
Pubmed

Distribution of KIR genes in the population of unrelated individuals homozygous for ancestral haplotype AH8.1 (HLA-A1B8DR3).

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.91e-1822101920492596
Pubmed

[Genotype and haplotype analysis of killer cell immunoglobulin-like receptors in ankylosing spondylitis].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

1.13e-1714101819489269
Pubmed

Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.13e-1714101818945962
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.41e-1715101819850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.41e-1715101820207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

2.41e-1715101819493232
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

2.41e-1715101817498266
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

4.81e-1716101816403292
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

9.07e-1717101819032228
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DS1

9.07e-1717101820173784
Pubmed

Immunogenetic characteristics of patients with autoimmune gastritis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

9.73e-1729101920082482
Pubmed

Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.63e-1618101820200544
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.63e-1618101820210918
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.68e-1610101712559621
Pubmed

Natural killer cells and immune surveillance.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.61e-1611101718830515
Pubmed

HLA and KIR frequencies in Sicilian Centenarians.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

4.66e-1620101820426625
Pubmed

Role of human leukocyte antigen, killer-cell immunoglobulin-like receptors, and cytokine gene polymorphisms in leptospirosis.

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

6.76e-1635101919683555
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1512101717490516
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.10e-1512101720137308
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5

1.44e-148101618681957
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1

4.30e-14910167749980
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS5 KIR3DL1 KIR3DS1

4.30e-14910168662091
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR3DL3 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

1.07e-1310101621206914
Pubmed

Activating killer cell immunoglobulin-like receptor gene KIR2DS1 is associated with psoriatic arthritis.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.87e-135101516112031
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

1.87e-135101518755860
Pubmed

Associations of killer cell immunoglobulin-like receptor genes with complications of rheumatoid arthritis.

KIR2DS2 KIR2DL2 KIR2DL3 KIR2DS1 KIR3DS1

1.12e-126101517882223
Pubmed

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DS5 KIR3DL1

3.91e-127101514607943
Pubmed

Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors.

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

3.91e-127101511169255
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR2DL1 KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

3.91e-12710159430220
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR2DS2 KIR2DL2 KIR2DL3 KIR3DL1 KIR3DS1

1.04e-118101517200871
Pubmed

A population-based cohort study of KIR genes and genotypes in relation to cervical intraepithelial neoplasia.

KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

1.04e-118101515730517
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR2DL1 KIR2DL3 KIR2DS1 KIR3DL1 KIR3DS1

1.04e-11810159430221
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR2DS2 KIR2DL1 KIR2DS1 KIR3DL1 KIR3DS1

2.33e-119101518340360
Pubmed

High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.

KIR2DL2 KIR2DL3 KIR3DL1 KIR3DS1

6.70e-114101419522772
Pubmed

LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence.

LILRA1 LILRA3 LILRB2 LILRB1

6.70e-114101421559424
Pubmed

[Distribution of immunoglobulin like receptor gene in Han population in China and the impact thereof on the HLA-identical sibling hematopoietic stem cell transplantation].

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.70e-114101418269867
Pubmed

Investigation of activating and inhibitory killer cell immunoglobulin-like receptors and their putative ligands in type 1 diabetes (T1D).

KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

6.70e-114101426542066
Pubmed

HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding.

LILRA1 LILRA3 LILRB2 LILRB1

6.70e-114101421270408
Pubmed

KIR gene in ethnic and Mestizo populations from Mexico.

KIR2DL2 KIR2DS1 KIR2DS5 KIR3DS1

3.34e-105101416698429
Pubmed

Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

KIR2DS2 KIR2DL1 KIR2DL3 KIR3DL1

3.34e-10510147716543
Pubmed

Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters.

LILRA3 KIR2DL1 KIR2DL2 KIR2DL3

3.34e-105101412121272
Pubmed

Diversity of the repertoire of p58 killer cell inhibitory receptors in a single individual.

KIR2DS2 KIR2DL1 KIR2DL3 KIR2DS1

3.34e-105101410424431
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.

KIR2DS2 KIR2DS1 KIR3DL1 KIR3DS1

1.00e-096101420528243
Pubmed

Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.33e-097101412618911
Pubmed

Expression of a killer cell receptor-like gene in plastic regions of the central nervous system.

KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.33e-097101415748957
Pubmed

A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules.

LILRA1 LILRA3 LILRB2 LILRB1

4.65e-09810149548455
Pubmed

Expression of testicular germ cell genes identified by differential display analysis.

ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

4.65e-098101412634303
Pubmed

Genotypes of NK cell KIR receptors, their ligands, and Fcγ receptors in the response of neuroblastoma patients to Hu14.18-IL2 immunotherapy.

KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

4.65e-098101420935224
Pubmed

Polymorphisms of killer cell immunoglobulin-like receptor gene: possible association with susceptibility to or clearance of hepatitis B virus infection in Chinese Han population.

KIR2DS2 KIR3DL3 KIR2DS1 KIR3DS1

8.35e-099101418074414
Pubmed

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model.

LILRA1 LILRB2 LILRB1 KIR3DL1

2.18e-0811101424052308
Pubmed

Prognostic role of KIR genes and HLA-C after hematopoietic stem cell transplantation in a patient cohort with acute myeloid leukemia from a consanguineous community.

KIR2DS2 KIR2DL1 KIR2DS1

2.38e-083101329549293
Pubmed

Killer cell immunoglobulin-like receptor (KIR) genes in the Basque population: association study of KIR gene contents with type 1 diabetes mellitus.

KIR2DL2 KIR2DS5 KIR3DS1

2.38e-083101316698433
Pubmed

Killer Immunoglobulin-Like Receptor 2DS2 (KIR2DS2), KIR2DL2-HLA-C1, and KIR2DL3 as Genetic Markers for Stratifying the Risk of Cytomegalovirus Infection in Kidney Transplant Recipients.

KIR2DS2 KIR2DL2 KIR2DL3

2.38e-083101330696053
InteractionLILRA3 interactions

LILRA1 LILRA3 MYCBP2 LILRB2 LILRB1

9.45e-1011955int:LILRA3
InteractionKIR2DL2 interactions

KIR2DS2 KIR2DL1 KIR2DL2 KIR3DL1 KIR3DS1

2.61e-0913955int:KIR2DL2
InteractionKIR3DL1 interactions

KIR2DS2 KIR2DL1 KIR2DL2 KIR3DL1

3.21e-0713954int:KIR3DL1
InteractionKIR3DP1 interactions

KIR2DS2 KIR2DL1 KIR2DS5

4.05e-074953int:KIR3DP1
InteractionKIR2DS2 interactions

KIR2DS2 KIR2DL2 KIR2DS1 KIR2DS5 KIR3DL1

8.10e-0737955int:KIR2DS2
InteractionHLA-C interactions

TSSK6 LILRB2 KIR2DS2 LILRB1 CNNM3 KIR3DL3 TMEM131L KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

8.56e-073539511int:HLA-C
InteractionANKRD20A4P interactions

ANKRD20A2P ANKRD20A4P ANKRD20A1

2.01e-066953int:ANKRD20A4P
InteractionKIR2DS3 interactions

KIR2DS2 KIR2DL1 KIR2DL2 KIR2DS5

2.12e-0620954int:KIR2DS3
InteractionANKRD20A2P interactions

ANKRD20A2P ANKRD20A4P ANKRD20A1

3.50e-067953int:ANKRD20A2P
InteractionANKRD20A1 interactions

ANKRD20A2P ANKRD20A4P ANKRD20A1

1.63e-0511953int:ANKRD20A1
InteractionLILRA1 interactions

LILRA1 LILRA3

2.20e-052952int:LILRA1
InteractionKIR2DS5 interactions

KIR2DS2 KIR3DL3 KIR2DS5

5.44e-0516953int:KIR2DS5
Cytoband19q13.4

LILRA1 LILRA3 LILRB2 KIR2DS2 LILRB1 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1 LILRA4

2.97e-21791011319q13.4
CytobandEnsembl 112 genes in cytogenetic band chr19q13

LILRA1 ODAD1 LILRB2 LILRB1 KIR3DL3 KIR2DL1 KLK5 KIR2DL3 KIR3DL1 LILRA4

3.05e-04119210110chr19q13
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 KIR3DS1

3.57e-1818679620
GeneFamilyADAM metallopeptidase domain containing|CD molecules

IGSF8 LILRA1 LILRA3 LILRB2 KIR2DS2 CR1 LILRB1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1 LILRA4

1.12e-113946715471
GeneFamilyCD molecules|Activating leukocyte immunoglobulin like receptors

LILRA1 LILRA3 LILRA4

9.65e-0766731181
GeneFamilyCD molecules|Inhibitory leukocyte immunoglobulin like receptors

LILRB2 LILRB1

1.34e-0456721182
GeneFamilyZinc fingers CXXC-type

MBD1 TET1

8.72e-0412672136
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CR1 CR1L NCAN

1.23e-03576731179
CoexpressionKAZMIN_PBMC_P_FALCIPARUM_RTSS_AS01_AGE_UNKNOWN_CORRELATED_WITH_PROTECTION_56DY_NEGATIVE

KIR2DS2 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.45e-11491018M40909
CoexpressionKIM_GLIS2_TARGETS_UP

VIM LILRA1 LILRB2 IGLV7-46 LILRB1 LTBP2

2.81e-061021016MM1064
CoexpressionGSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN

KIR2DS2 KIR3DL3 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

9.12e-061901017M4662
CoexpressionGSE22886_DC_VS_MONOCYTE_DN

LILRA1 LILRA3 MYCBP2 LILRB2 LILRB1 CNNM3 TMEM131L

1.27e-052001017M4472
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_POSITIVE

LILRA1 LILRA3 LILRB2 CR1 LILRB1 ORAI3 RAB1B KIR2DL2 KIR3DL1

4.06e-054261019M41019
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CD16_POS_NK_CELL

KIR2DL1 KIR2DL3 KIR3DL1

4.34e-05181013M45763
CoexpressionCUI_TCF21_TARGETS_2_UP

IGSF8 FN1 APCDD1 PATZ1 SLIT2 CLCN2 TET1 ELAPOR1 CA4

4.94e-054371019M1610
CoexpressionSOUCEK_MYC_TARGETS

LILRA1 LILRB2 LILRB1

5.15e-05191013MM1252
CoexpressionCUI_TCF21_TARGETS_2_UP

IGSF8 FN1 APCDD1 PATZ1 SLIT2 CLCN2 TET1 ELAPOR1 CA4

6.74e-054551019MM1189
ToppCellCOVID_vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

LILRA1 LILRA3 ITLN1 LILRB2 LILRB1 HOXA1 CCM2L

2.14e-07194967b133d3d198360269cc449a75d34c29be377d91e0
ToppCell390C-Lymphocytic-NK_cells-NK_cell_C|390C / Donor, Lineage, Cell class and subclass (all cells)

ANKRD20A2P ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1 ANKRD20A1

3.23e-061879661e8651e6c547384ace5a66b96c6b24a7f390a7ee
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 GPATCH8 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

3.33e-061889669abd78970bbe4ed03b59a83da63bbd334712f605
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 GPATCH8 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

3.33e-06188966f7dc29dfec68236883469e848be5db34f5526d6b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 GPATCH8 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

3.33e-061889665ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PARP8 GPATCH8 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

3.76e-061929661922b0350d3375e67c314dbce8074e5cf986f2ef
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PARP8 GPATCH8 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

3.76e-0619296697c197643e59835c6d45dde9e549c9a1b1bb7288
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PARP8 GPATCH8 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

3.76e-06192966a4d161e3d48bc020e687808b352325ef9d1cc1f3
ToppCelldroplet-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIM FN1 KDM6B LOXL1 ARID5B GNAS

3.88e-06193966e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIM FN1 CR1 CR1L NPB LTBP2

3.99e-06194966f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCell343B-Myeloid-Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

VIM LILRA1 LILRB2 KDM6B CR1 LILRB1

4.11e-06195966169b4952118ca5ded55de928a1cf08721cdac193
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIM FN1 CR1 CR1L NPB LTBP2

4.11e-061959661be9502577267ca2a04656a99d57e3e2f124d92e
ToppCellCOPD-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

HIPK2 ANKRD20A2P ANKRD20A3P ANKRD20A4P ATOH8 CA4

4.36e-0619796630dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCellNS-control-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VIM LILRA1 LILRA3 LILRB2 CR1 LILRB1

4.36e-06197966496a1115071a1be6928786192de49f3adf197dfb
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LILRA1 DOCK8 LILRB2 RAPGEF1 CR1 LILRB1

4.62e-06199966ac866ae110967c5867ff4601939b79861d43df54
ToppCell5'-Adult-SmallIntestine-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 APCDD1 MAP3K20 SLIT2 LOXL1 SEMA3E

4.76e-06200966a637281d91e95734ee4f8510b3780e0272b16fda
ToppCellSigmoid-(4)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

LILRA1 LILRB2 DDO CR1 CCM2L ATOH8

4.76e-062009667f3920a0434d5199c6c8f0b3064a305bb0d87b60
ToppCellSigmoid-Monocyte-Monocyte|Sigmoid / Region, Cell class and subclass

LILRA1 LILRB2 DDO CR1 CCM2L ATOH8

4.76e-06200966010ca36970cb8894bdbca08779c0ecf56be22fc9
ToppCellSigmoid-Monocyte|Sigmoid / Region, Cell class and subclass

LILRA1 LILRB2 DDO CR1 CCM2L ATOH8

4.76e-06200966c41bd6ec0f2262fce5cadb37a400d487e6662f49
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LILRA1 DOCK8 LILRB2 RAPGEF1 CR1 LILRB1

4.76e-062009668872d5fa101d413fb43b4231d476878678543035
ToppCellSigmoid-(4)_Monocyte-(40)_Monocyte|Sigmoid / shred on region, Cell_type, and subtype

LILRA1 LILRB2 DDO CR1 CCM2L ATOH8

4.76e-06200966576c0a1098e6a934448705de3673ef798fcf1b26
ToppCellBronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LILRA1 DOCK8 LILRB2 RAPGEF1 CR1 LILRB1

4.76e-06200966fc061de0db2e8b5ca47f5e2a1e861018e7f1b582
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

HOXA1 RSPH10B2 ANKRD20A4P NPB TET1

2.16e-05155965e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ITLN1 HIPK2 KIR3DL3 KIR2DL1 KIR2DL3

2.23e-05156965e6798d2b9c2c1fc6525c24f596f25aa85a375651
ToppCell367C-Lymphocytic-NK_cells-NK_cell_C|367C / Donor, Lineage, Cell class and subclass (all cells)

GPATCH8 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

2.23e-05156965a1b9e7621b646d354c2ccd850ce6a4fa9ff8a026
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 APCDD1 LOXL1 LRRC8A MUC5AC

3.09e-05167965805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 APCDD1 LOXL1 LRRC8A MUC5AC

3.09e-0516796531cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 APCDD1 LOXL1 LRRC8A MUC5AC

3.09e-051679653acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PARP8 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

3.65e-0517396579d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ANKRD20A2P ANKRD20A3P ANKRD20A4P LOXL1 ELAPOR1

3.76e-05174965a0060be3940043015dcc49a5157de5541aed24a1
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EML4 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

4.41e-05180965ddbab26b05f057bd78b78773381cd447bd2e2726
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK8 EML4 PARP8 ANKRD20A2P KIR2DL3

4.90e-0518496517ffa0e890960c00a3b5fa33d48caba66c61dbb0
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

4.90e-05184965c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

4.90e-0518496542d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellCOVID-19-Heart-Fib_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FN1 APCDD1 SLIT2 LOXL1 LTBP2

5.03e-051859658f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCellControl-T_cells-NK_cells|Control / group, cell type (main and fine annotations)

CLASP1 PARP8 KIR2DL1 KIR2DL3 KIR3DL1

5.03e-05185965755c0998c729f462399f1d5e88adf4bfae31be30
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

5.16e-05186965962c2dada19185628ead77c32fcb07fa95114247
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLASP1 ODAD1 HOXA1 TNKS1BP1 FLRT1

5.16e-05186965c116cc9f41971622264434ebe29d18e719b0ae19
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

GBF1 CLASP1 MYCBP2 DOCK8 TMEM131L

5.16e-051869658571956890fc9894d766ba294a28e376b4aba428
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

5.16e-05186965b05c394aa3573ba855abc3066739ca193883b0c3
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FN1 APCDD1 SLIT2 LOXL1 LTBP2

5.29e-051879654ea486991f66c29728d127171a07b81404ec0b78
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

5.43e-0518896547bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

5.43e-051889652331a2bae1383820d598e93aa86c75b101069bac
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EML4 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

5.56e-05189965723c57f278919e8251d56b3d19411f9088319450
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EML4 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

5.56e-05189965960374f5fb278659500a7c948c3068a95dd62eb0
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PARP8 GPATCH8 KIR2DL1 KIR2DL3 KIR3DL1

5.70e-051909651f890be1ac8613a098b271945f25a58c3c2530ab
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

RAPGEF1 ANKRD20A2P ANKRD20A4P ATOH8 CA4

5.70e-051909657f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PARP8 GPATCH8 KIR2DL1 KIR2DL3 KIR3DL1

5.70e-05190965d7cecf88451f736f8f3f6f4644504cf22846cd6e
ToppCell(1)_T_cells-(1)_T_CD8_gd|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MBD1 LILRB1 KIR3DL3 KIR2DL1 KIR3DL1

5.70e-05190965268772d2adff34f7175b8474e95b67fd96dc1234
ToppCellNS-critical-d_16-33-Myeloid-Non-resident_Macrophage|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VIM LILRA1 LILRA3 LILRB2 LILRB1

5.70e-051909654fe9654a9b449ef49ca10b973ac4378dab34cb53
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|lymph-node_spleen / Manually curated celltypes from each tissue

PARP8 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

5.85e-05191965f802a4686ecf00e8302047bfe23356f24b266cf8
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

VIM LILRA3 LILRB2 MAP3K20 CR1

5.85e-05191965c9f3bdb5c0a90268cab24a0fe4c3a8290fcedeb8
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

5.85e-051919653480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK8 LILRB2 MAP3K20 CR1 LILRB1

5.85e-0519196547a2afc4102199b4bc76bd01b2967c8016186462
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

ANKRD20A2P ANKRD20A3P ANKRD20A8P ANKRD20A4P ANKRD20A1

5.99e-05192965bd3d00b094d92463b06023361a71240851a542b8
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

PARP8 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

5.99e-051929654d72b9264ed62e0c08cde4078061b348253f6989
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

VIM LILRA3 LILRB2 MAP3K20 CR1

5.99e-05192965b86476037ddf8904c1d8a6b3763af7242c031cf3
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIM FN1 SLIT2 LOXL1 LTBP2

5.99e-051929658171a60df481195c39a7f740effcae8e4deb6ca7
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

VIM DOCK8 EML4 HIPK2 RAPGEF1

6.14e-05193965cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

MYCBP2 PPFIBP2 CR1 ARID5B TMEM131L

6.14e-051939657ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell10x5'v1-week_14-16-Lymphocytic_NK-T_NK-CD56_bright_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EML4 PARP8 KIR2DL1 KIR2DL3 KIR3DL1

6.14e-0519396546f94a1062b098205e8ce3ed380c0202a4d97678
ToppCellICU-SEP-Lymphocyte-T_NK-NK|ICU-SEP / Disease, Lineage and Cell Type

ANKRD20A4P KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

6.14e-05193965f110f86db305e41639087f5b1a2dff103c07adf0
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYCBP2 RAPGEF1 CR1 CDK13 ARID5B

6.30e-05194965ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellCOVID_non-vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

LILRA1 LILRA3 ITLN1 LILRB2 LILRB1

6.30e-051949651b4a17d58793e8889484fe592dce8ee1e8fe77a9
ToppCellLV-02._Fibroblast_II|LV / Chamber and Cluster_Paper

VIM FN1 APCDD1 SLIT2 LTBP2

6.30e-05194965014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIM DOCK8 EML4 HIPK2 RAPGEF1

6.30e-0519496569cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

VIM FN1 SLIT2 LOXL1 LTBP2

6.30e-05194965d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK|Leuk-UTI / Disease, Lineage and Cell Type

GPATCH8 KIR3DL3 KIR2DL1 KIR2DL3 KIR3DL1

6.30e-0519496536afc4e48d267be3b8aa1e33fad043bcd54c6bc5
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LILRA1 DOCK8 LILRB2 CR1 LILRB1

6.30e-05194965dfe0ece81922bfd7c6673726d3ea2365cbdb5513
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LILRA1 DOCK8 LILRB2 CR1 LILRB1

6.45e-051959654387e27d2288fb46a9ed110464542a4aea402358
ToppCellAdult-Immune-monocyte-D231|Adult / Lineage, Cell type, age group and donor

LILRA1 DOCK8 LILRB2 RAPGEF1 LILRB1

6.45e-05195965ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

VIM FN1 APCDD1 SLIT2 LTBP2

6.45e-05195965f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCellNS-critical-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VIM LILRA1 LILRA3 LILRB2 LILRB1

6.45e-05195965ee8743d39996bb756f50db32748e8a902d3294b8
ToppCell343B-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 LILRB2 KDM6B LILRB1 LILRA4

6.45e-05195965d1ec768573929c717bb6b20ad5f26c4549cfcaed
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

6.45e-0519596598b02beafe1d418442e41f85cbf0c7b194fe5957
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

6.45e-051959659ecae6c26a0d0607d101ccf1c38f0b23c5a256a8
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

VIM LILRA1 LILRB2 KDM6B CR1

6.45e-05195965b5ee368c97113432fc8fe742654cd538558f327c
ToppCellcontrol-Myeloid-Non-resident_Macrophage|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

VIM LILRA1 LILRB2 CR1 LILRB1

6.61e-05196965646a8d47dddffdfd2d8a62245ea6cd49f9510a1a
ToppCelldistal-Hematologic-OLR1+_Classical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LILRA1 LILRB2 MAP3K20 KDM6B LILRB1

6.61e-0519696580fc5b9e04ead0b38304dccbe39f66575e2bf203
ToppCellAdult-Immune-monocyte|Adult / Lineage, Cell type, age group and donor

LILRA1 DOCK8 LILRB2 RAPGEF1 LILRB1

6.61e-051969653ef193c5180de3137daf886492e74fc574bc9767
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Neutrophils|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

VIM LILRA1 LILRB2 LILRB1 LILRA4

6.61e-05196965376c5a459a484205fbb0db34936e4a6146d1f622
ToppCellBL-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HIPK2 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1

6.61e-05196965cfbeaabbeeb197f0cf8240a752d1f2995d59d7b7
ToppCellSevere-NK|Severe / Disease group and Cell class

HIPK2 LILRB1 KIR2DL1 KIR2DL3 KIR3DL1

6.61e-0519696566130d38b67e51e2385de8a89227759fd137999c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

6.61e-051969659b3848dd4256cd6d9a21ef6bfdbd0cb7c0030005
ToppCelldistal-Hematologic-OLR1+_Classical_Monocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LILRA1 LILRB2 MAP3K20 KDM6B LILRB1

6.61e-051969653f57216dbc9ef28fca09bbb8805f7c15b03b99e8
ToppCellChildren_(3_yrs)-Immune-monocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

LILRA1 DOCK8 LILRB2 CR1 LILRB1

6.61e-05196965cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

6.61e-0519696578b28b263deaa43590b38597186222c6447ad25f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

6.61e-051969653e78e307c9c991c1aadc85c61d401431cf75eaec
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HIPK2 ANKRD20A4P KIR2DL1 KIR2DL3 KIR3DL1

6.61e-05196965f0566f2ef96584ed6d9247b149218376fb509915
ToppCellFetal_29-31_weeks-Immune-monocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LILRA1 DOCK8 LILRB2 RAPGEF1 LILRB1

6.77e-0519796548a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCellPND03-Mesenchymal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIM FN1 SLIT2 LOXL1 LTBP2

6.77e-05197965e3053ef8f604b6892c21c03e12612b49d3d30f23
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

LILRA1 DOCK8 LILRB2 CR1 LILRB1

6.77e-05197965a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VIM LILRA1 LILRB2 MAP3K20 LILRB1

6.77e-0519796559aa4a31674125ae422450aee45db3ced5c405d3
ToppCellSevere-NK|World / Disease group and Cell class

HIPK2 LILRB1 KIR2DL1 KIR2DL3 KIR3DL1

6.77e-051979651e5fb79385657a467c2d9f942d8cafb8ef7826c9
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

VIM DOCK8 EML4 RAPGEF1 TMEM131L

6.77e-05197965f18807124b91310fcd84238484a80ecdba684679
ToppCellFetal_29-31_weeks-Immune-monocyte-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LILRA1 DOCK8 LILRB2 CR1 LILRB1

6.77e-051979658b9a88fb671d5c2b25d291c851e2b8a478f2610c
ToppCellInfluenza_Severe-NK|World / Disease group and Cell class

PARP8 GPATCH8 KIR2DL1 KIR2DL3 KIR3DL1

6.77e-05197965565d578f7a28a19175d56663bf30c60e0d5e1b22
ToppCellDendritic_cell|World / shred by cell class for turbinate

VIM LILRA1 LILRB2 LILRB1 LILRA4

6.77e-05197965ab2213e3742f92798922ea318d76328b6ca18b13
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-stromal_related|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIM NPB LOXL1 ARID5B LTBP2

6.77e-05197965ea9332adf753d7e92f89654320543abb9e6142aa
ToppCell343B-Myeloid-Monocyte-CD16+_Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 LILRB2 KDM6B LILRB1 LILRA4

6.77e-051979658d6551e118cfe308088487c6d5171d986f90fb2f
ComputationalNeighborhood of IL2RB

KIR2DS2 KIR3DL3 KIR2DL1 KIR3DL1

9.82e-0546574GNF2_IL2RB
DrugD-Au

LILRB1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

1.71e-09771008CID000277822
DrugAa1

EPX KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5 KIR3DL1

3.13e-09831008CID009549188
DrugIL-T

LILRA1 LILRA3 LILRB2 LILRB1 KIR3DL1 LILRA4

1.68e-07561006CID000150551
DrugPentolinium bitartrate [52-62-0]; Down 200; 7.4uM; HL60; HT_HG-U133A

SETD1A EML4 HIPK2 KDM6B LILRB1 CNNM3 KLK5 LRRFIP2

2.57e-0619710082343_DN
Drug1xa5

EXOSC1 KIR3DL3 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DS1

3.45e-06931006CID000157684
DrugLTC4 (leukotriene C4

LILRA1 LILRA3 LILRB2 EPX CR1L LILRB1 KLK5

1.48e-051801007CID000003907
Drug1c88

RAPGEF1 KIR3DL3 KIR2DL2 KIR2DL3 KIR2DS1 KIR2DS5

1.99e-051261006CID000444766
Drugauramine

ITLN1 MBD1 TET1

2.89e-05141003CID000010298
DrugIdoxuridine [54-42-2]; Up 200; 11.2uM; PC3; HG-U133A

PATZ1 MBD1 MAP3K20 KDM6B SBNO1 CDK13 FLRT1

2.92e-0520010071899_UP
DrugPivmecillinam hydrochloride [32887-03-9]; Up 200; 8.4uM; PC3; HT_HG-U133A

RAB35 FN1 LILRB2 EPX CDK13 LTBP2 MUC5AC

2.92e-0520010077312_UP
DrugAGN 1135

LOXL1 KIR2DL1 KIR2DL2 KIR2DL3 KIR3DL1 CA4

3.75e-051411006CID000122316
Diseaselevel of killer cell immunoglobulin-like receptor 2DS2 in blood serum

KIR3DL3 KIR2DL1 KIR2DL3

2.84e-083913OBA_2042107
Diseasekiller cell immunoglobulin-like receptor 2DS2 measurement

KIR3DL3 KIR2DL1 KIR2DL3

1.26e-0515913EFO_0801746
Diseasemalaria (is_implicated_in)

CR1 KIR3DL1 KIR3DS1

5.48e-0524913DOID:12365 (is_implicated_in)
Diseaseblood sedimentation

CR1 CR1L

1.96e-047912EFO_0004304
Diseaseanxiety, vitamin D measurement

DOCK8 SEMA3E

1.96e-047912EFO_0004631, EFO_0005230
Diseaseacquired immunodeficiency syndrome (is_implicated_in)

KIR2DL1 KIR3DS1

3.34e-049912DOID:635 (is_implicated_in)
Diseaseinterleukin 7 measurement

LILRA1 PARP8 LILRB1

3.67e-0445913EFO_0008189
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 2 measurement

LILRB2 LILRB1

5.08e-0411912EFO_0008209
DiseaseMental Retardation, Psychosocial

PECR DOCK8 KDM6B GNAS

9.18e-04139914C0025363
DiseaseProfound Mental Retardation

PECR DOCK8 KDM6B GNAS

9.18e-04139914C0020796
DiseaseMental deficiency

PECR DOCK8 KDM6B GNAS

9.18e-04139914C0917816
Diseaseleukocyte immunoglobulin-like receptor subfamily B member 1 measurement

LILRA1 LILRB1

9.62e-0415912EFO_0008208
Diseaseresponse to ketamine

DOCK8 PPFIBP2 SLIT2

1.28e-0369913EFO_0009748
Diseaseanthropometric measurement

FN1 MYCBP2 LOXL1 LTBP2

1.84e-03168914EFO_0004302
Diseasedilated cardiomyopathy (implicated_via_orthology)

EXOSC1 ORAI3 LTBP2

1.96e-0380913DOID:12930 (implicated_via_orthology)
Diseasenephrosis (biomarker_via_orthology)

VIM PTPRU

2.09e-0322912DOID:2527 (biomarker_via_orthology)
Diseasecup-to-disc ratio measurement

EML4 RAPGEF1 LOXL1 TET1 ARID5B LTBP2

2.17e-03430916EFO_0006939
DiseaseUreteral obstruction

FN1 HIPK2

2.48e-0324912C0041956
Diseaseaortic root size

KCTD7 LOXL1

2.91e-0326912EFO_0005037

Protein segments in the cluster

PeptideGeneStartEntry
GSIDHVYTGSGYRIR

ANKRD20A1

16

Q5TYW2
ISFRGAYHGCSPYTL

AGXT2

191

Q9BYV1
GSIDHVYTGSGYRIR

ANKRD20A8P

16

Q5CZ79
GSIDHVYTGSGYRIR

ANKRD20A4P

16

Q4UJ75
RYGEDYSRSRGSPSS

EPN3

171

Q9H201
CVDRAGYHYTSTPER

CCM2L

336

Q9NUG4
RSPSYSRHSSYERGG

CDK13

366

Q14004
AYGTRCRYDHTRPSA

MKRN2

46

Q9H000
RTITSSYYRGAHGII

RAB1B

71

Q9H0U4
RTITSTYYRGTHGVI

RAB35

71

Q15286
DYTYSTVPRRCGGSH

QRICH2

1546

Q9H0J4
CGGSHTLTYPYHRSR

QRICH2

1556

Q9H0J4
GTYRCYGSVTHSPYQ

KIR2DS2

96

P43631
PAGSATYREFVHRGY

ORAI3

21

Q9BRQ5
SLTGYRTYRCAHPLA

LRRC8A

301

Q8IWT6
GSIDHVYTGSGYRIR

ANKRD20A2P

16

Q5SQ80
RPGESSYSSISHVIY

ATOH8

186

Q96SQ7
RRIYSFYSSLGCGHS

RSPH10B

421

P0C881
RRIYSFYSSLGCGHS

RSPH10B2

421

B2RC85
RSLGYHGSSYSPEGV

NCOR2

2036

Q9Y618
FTYVGGPRSVSYSVH

PARP8

41

Q8N3A8
YGTHVGYSSSREITE

ITLN1

291

Q8WWA0
GTYRCYGSVTHSPYQ

KIR2DL2

96

P43627
TLSPVSRSYGGQYRC

LILRA4

281

P59901
TSAHAGTYRCYGSRS

LILRA4

386

P59901
FSGRHYIPTDSEGRY

KCTD7

81

Q96MP8
HLYTYTAPAALGSTG

HIPK2

1101

Q9H2X6
YSTRYSTQVSHIGPG

LEXM

56

Q3ZCV2
GTYRCYGSVTHSPYQ

KIR2DL3

96

P43628
IDYSRGSIYHSVEGP

KIAA1109

1426

Q2LD37
PAGYYIDRDSGTCHS

ELAPOR1

606

Q6UXG2
YCYRGTGAAVSTRPG

KDM6B

816

O15054
DRRYSHSLYSEGTPG

LOXL1

271

Q08397
GTYRCYGSVTHTPYQ

KIR3DL1

191

P43629
ATCGRSDTYYQSPTG

MBD1

26

Q9UIS9
YRSQSPHYFRSGRGE

GPATCH8

1031

Q9UKJ3
YRTGRTLHGQETYTP

MSTO1

51

Q9BUK6
RTLGHYRGYCSNVDP

EPX

446

P11678
VDGGRSLYTHSYEVP

PECR

261

Q9BY49
GTYRCFGSVTHLPYE

KIR3DL3

191

Q8N743
VTSAHAGTYRCYGSL

LILRB2

386

Q8N423
SPGSGTYTRHGYIFS

EXOSC1

21

Q9Y3B2
TPACAGGRSVYTEAY

IL17D

146

Q8TAD2
VRLGHYSLSPVYESG

KLK5

116

Q9Y337
YPAGSTIYRHRDLAG

MUC5AC

4791

P98088
LGVSYSHSSCGPSYG

HOXA1

86

P49639
PTRGSARAAGYDLYS

DUT

126

P33316
GSSPYTSSRCRRELY

PELP1

566

Q8IZL8
FRPVSASSYLGSTGY

ODAD1

601

Q96M63
PSDGVSDSHRVYSGY

PPFIBP2

841

Q8ND30
SDSHRVYSGYRGLSP

PPFIBP2

846

Q8ND30
GPRTPSECSYYSSRI

LRRFIP2

216

Q9Y608
GTYRCYGSVTHSPYQ

KIR2DS5

96

Q14953
LYSRDGHSPGTLGVY

PTPRU

106

Q92729
RDGSGLTYIYPGTSH

DDO

216

Q99489
PSGCYTYQVSRHSTE

PATZ1

11

Q9HBE1
GSIDHVYTGSGYRIR

ANKRD20A3P

16

Q5VUR7
RSGDVYGYSSCTANP

CCDC71

66

Q8IV32
ECHTPSTDTRYLGSY

IGSF8

126

Q969P0
HYFRYLGSLTTPTCD

CA4

216

P22748
DPRSYHTYGRTSAAA

DOCK8

876

Q8NF50
HYGSVVTYRCNPGSG

CR1

186

P17927
HYGSVVTYRCNPGSG

CR1

636

P17927
SRYRVTYSSPEDGIH

FN1

1751

P02751
GYDLRGSTYLHCTPQ

CR1L

321

Q2VPA4
LRISTASGDGRHYCY

GNAS

346

P63092
HPTFSIYARGRYSRG

APCDD1

336

Q8J025
YSGKSQHSTPSRGRY

MAP3K20

696

Q9NYL2
REICPAGHGYTYASS

LTBP2

721

Q14767
YTSDSEVYTDHGRPG

GBF1

1316

Q92538
SSRSCGGYLHYPASS

KRTAP13-1

11

Q8IUC0
YSRYGRCTGHSSYIT

EML4

711

Q9HC35
ATHTIGYGTTRGYRD

FLRT1

621

Q9NZU1
SPCERKGRSYGSYNT

RNF103

586

O00237
TPGYSTSGHVELYTI

SBNO1

1166

A3KN83
GTYRCYGSVTHSPYQ

KIR2DL1

96

P43626
CGSSTGAVTSGHYPY

IGLV7-46

41

A0A075B6I9
PVSRSYGGQYTCSGA

LILRA3

286

Q8N6C8
PVTSAHAGTYRCYGS

LILRA3

386

Q8N6C8
HAGTYRCYGSLSSNP

LILRA3

391

Q8N6C8
GTYVFSYHITVRGRP

OTOL1

386

A6NHN0
VSAYSSTYHRAGCKP

OSBPL7

541

Q9BZF2
GTYRCYGSVTHSPYQ

KIR2DS1

96

Q14954
SYGVLSYHVSGIGTR

TMEM131L

176

A2VDJ0
PVSRSYGGQYRCSGA

LILRA1

286

O75019
PVTSAHSGTYRCYGS

LILRA1

386

O75019
HSGTYRCYGSLSSNP

LILRA1

391

O75019
PVTSAHAGTYRCYGS

LILRB1

386

Q8NHL6
HAGTYRCYGSQSSKP

LILRB1

391

Q8NHL6
GTYRCYGSVTHTPYQ

KIR3DS1

191

Q14943
GCYGDRSSLPGVRSY

NCAN

226

O14594
YSGTVRGHIYNSTSR

MYCBP2

391

O75592
YKPAAGHSSYSVGRA

NPB

26

Q8NG41
PARRQDSSGSSGSYY

PROB1

21

E7EW31
PREHQTGSARSEGYY

SETD1A

1486

O15047
SHGTILYIYCRPSSG

OR5L2

251

Q8NGL0
YYTHLGAGPSVAAVR

TET1

1436

Q8NFU7
YRHLAAATPVGSSYG

ARID5B

1141

Q14865
SERSYGSRNGGIPHY

CLASP1

836

Q7Z460
HTDSSTYRIVPGGYA

CLCN2

486

P51788
GDGTHSSAYCPDYTV

CNNM3

616

Q8NE01
EETSRYLDGYCPSGS

TMEM215

156

Q68D42
AYSRDHSPKAYSGGR

RBMXL3

356

Q8N7X1
GYPHIRYISSGLDGT

RNF111

856

Q6ZNA4
GSGCRVSYERHPSQY

RAPGEF1

471

Q13905
HDGSSRYGPRTYGTT

TNKS1BP1

191

Q9C0C2
SLYASSPGGVYATRS

VIM

51

P08670
YRGRVRASYDTGSHP

SLIT2

1211

O94813
AHGYPDLSTTYCGSA

TSSK6

161

Q9BXA6
GISCSRYYPTGTHAK

SEMA3E

541

O15041
GSVSNYPRYTGSRSC

nan

66

Q6ZVU0
YGYCSGGSRSRIPHS

VN1R3

166

Q9BXE9
DYEYGSRGPLTACSG

TMEM198

341

Q66K66