Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF18A KIF27 MYO9B CHD8 INO80 DDX10 MLH3 NAV3 MACF1 KIF22	7.34e-05	441	100	10	GO:0016887
GeneOntologyMolecularFunction	pyrophosphatase activity	ENTPD7 PRUNE2 KIF18A KIF27 MYO9B MTG2 CHD8 INO80 DDX10 MLH3 NAV3 MACF1 DCP1A KIF22	7.38e-05	839	100	14	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	ENTPD7 PRUNE2 KIF18A KIF27 MYO9B MTG2 CHD8 INO80 DDX10 MLH3 NAV3 MACF1 DCP1A KIF22	7.48e-05	840	100	14	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	ENTPD7 PRUNE2 KIF18A KIF27 MYO9B MTG2 CHD8 INO80 DDX10 MLH3 NAV3 MACF1 DCP1A KIF22	7.48e-05	840	100	14	GO:0016818
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	FLI1 ZNF536 MYBBP1A CUX2 TGIF2 HIVEP1 FOXB2 ZNF711 NFE2L3 SOX7 NFE2L2 ZNF587 ZNF335 ELK1 PAX7 ZNF417	4.41e-04	1244	100	16	GO:0000978
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	ENTPD7 KIF18A KIF27 MYO9B MTG2 CHD8 INO80 DDX10 MLH3 NAV3 MACF1 KIF22	4.93e-04	775	100	12	GO:0017111
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	FLI1 ZNF536 MYBBP1A CUX2 TGIF2 HIVEP1 FOXB2 ZNF711 NFE2L3 SOX7 NFE2L2 ZNF587 ZNF335 ELK1 PAX7 ZNF417	5.57e-04	1271	100	16	GO:0000987
GeneOntologyMolecularFunction	ATP-dependent activity	KIF18A KIF27 MYO9B CHD8 INO80 DDX10 MLH3 NAV3 MACF1 KIF22	1.01e-03	614	100	10	GO:0140657
GeneOntologyCellularComponent	chromatin	FLI1 MYBBP1A CUX2 TGIF2 FOXB2 CHD8 ICE1 SIN3A INO80 ZNF711 CITED2 NFE2L3 SOX7 ARID1B PELP1 NFE2L2 BRPF1 ELK1 PAX7 KIF22	1.99e-05	1480	100	20	GO:0000785
Domain	Kinesin_motor_CS	KIF18A KIF27 KIF22	1.18e-03	41	95	3	IPR019821
Domain	Kinesin-like_fam	KIF18A KIF27 KIF22	1.36e-03	43	95	3	IPR027640
Domain	KINESIN_MOTOR_1	KIF18A KIF27 KIF22	1.45e-03	44	95	3	PS00411
Domain	-	KIF18A KIF27 KIF22	1.45e-03	44	95	3	3.40.850.10
Domain	Kinesin_motor_dom	KIF18A KIF27 KIF22	1.45e-03	44	95	3	IPR001752
Domain	Kinesin	KIF18A KIF27 KIF22	1.45e-03	44	95	3	PF00225
Domain	KINESIN_MOTOR_2	KIF18A KIF27 KIF22	1.45e-03	44	95	3	PS50067
Domain	KISc	KIF18A KIF27 KIF22	1.45e-03	44	95	3	SM00129
Domain	bZIP_Maf	NFE2L3 NFE2L2	1.93e-03	13	95	2	IPR004826
Domain	bZIP_Maf	NFE2L3 NFE2L2	1.93e-03	13	95	2	PF03131
Domain	-	NFE2L3 NFE2L2	2.93e-03	16	95	2	1.10.880.10
Domain	PBD	CDC42BPG PAK6	3.31e-03	17	95	2	PF00786
Domain	CH	MICAL1 NAV3 MACF1	4.43e-03	65	95	3	SM00033
Domain	CRIB	CDC42BPG PAK6	4.58e-03	20	95	2	PS50108
Domain	CRIB_dom	CDC42BPG PAK6	5.05e-03	21	95	2	IPR000095
Domain	CH	MICAL1 NAV3 MACF1	5.46e-03	70	95	3	PF00307
Domain	-	MICAL1 NAV3 MACF1	5.68e-03	71	95	3	1.10.418.10
Domain	CH	MICAL1 NAV3 MACF1	6.13e-03	73	95	3	PS50021
Domain	CH-domain	MICAL1 NAV3 MACF1	6.61e-03	75	95	3	IPR001715
Domain	ETS_DOMAIN_1	FLI1 ELK1	8.88e-03	28	95	2	PS00345
Domain	ETS_DOMAIN_2	FLI1 ELK1	8.88e-03	28	95	2	PS00346
Domain	ETS	FLI1 ELK1	8.88e-03	28	95	2	SM00413
Domain	Ets_dom	FLI1 ELK1	8.88e-03	28	95	2	IPR000418
Domain	ETS_DOMAIN_3	FLI1 ELK1	8.88e-03	28	95	2	PS50061
Domain	Ets	FLI1 ELK1	8.88e-03	28	95	2	PF00178
Pubmed	Human transcription factor protein interaction networks.	FLI1 ASXL1 ZNF536 MYBBP1A HIVEP1 RADX CHD8 ZNF318 SIN3A INO80 TNRC6C HMG20B DDX10 YTHDF1 NOL4L ARID1B AUTS2 PAX7 USP54 DCP1A	6.57e-09	1429	103	20	35140242
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	ZNF536 CUX2 TGIF2 HIVEP1 MKRN2 ZNF318 HMG20B CITED2 SOX7 NDRG1 BRPF1 MACF1 PAX7 DCP1A	2.44e-08	709	103	14	22988430
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF536 TCOF1 CHD8 ZNF318 SIN3A INO80 PSMG3-AS1 HMG20B ZNF711 ARID1B MLH3 MTHFR BRPF1 MACF1 USP54 LONRF3	1.86e-07	1116	103	16	31753913
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 ASXL1 CUX2 CHD8 TNRC6C MED13L AUTS2 MACF1	3.80e-07	225	103	8	12168954
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MYBBP1A HIVEP1 TCOF1 ZNF318 SIN3A FASN NOL4L NDRG1 ZNF335 FHOD1 BRPF1 PHACTR4 DCP1A	5.05e-07	774	103	13	15302935
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 CRTC3 CUX2 TCOF1 ASAP3 SCYL1 SIN3A NFE2L2 PAX7 NYAP1	6.38e-07	430	103	10	35044719
Pubmed	Interaction network of human early embryonic transcription factors.	FLI1 ZNF536 HIVEP1 CHD8 INO80 HMG20B TOMM70 ARID1B AUTS2	1.07e-06	351	103	9	38297188
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FLI1 SDE2 HIVEP1 RADX CHD8 SIN3A INO80 DDX10 ZNF711 BRPF1 KIF22	1.99e-06	608	103	11	36089195
Pubmed	A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.	FLI1 ZNF536 PPP1R3B NAV3	2.45e-06	32	103	4	23049088
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SDE2 MYBBP1A TCOF1 ICE1 ZNF318 SIN3A DDX10 FASN NDRG1 FHOD1 MACF1 DCP1A AHNAK2	4.01e-06	934	103	13	33916271
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF536 HIVEP1 CHD8 ICE1 ZNF318 HMG20B FASN NOL4L DCP1A	4.45e-06	418	103	9	34709266
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	CHD8 SIN3A INO80 ARID1B BRPF1 AUTS2	7.66e-06	157	103	6	30186101
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	MYBBP1A TCOF1 SCYL1 CHD8 SIN3A DDX10 ARID1B DCP1A	8.33e-06	341	103	8	32971831
Pubmed	Lifelong restructuring of 3D genome architecture in cerebellar granule cells.	CHD8 ARID1B	8.69e-06	2	103	2	37676945
Pubmed	Nrf3 promotes UV-induced keratinocyte apoptosis through suppression of cell adhesion.	NFE2L3 NFE2L2	8.69e-06	2	103	2	29487353
Pubmed	SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.	ENTPD7 ARID1B	8.69e-06	2	103	2	27737960
Pubmed	The autism risk factor CHD8 is a chromatin activator in human neurons and functionally dependent on the ERK-MAPK pathway effector ELK1.	CHD8 ELK1	8.69e-06	2	103	2	36575212
Pubmed	Impaired folate 1-carbon metabolism causes formate-preventable hydrocephalus in glycine decarboxylase-deficient mice.	GLDC MTHFR	8.69e-06	2	103	2	31794432
Pubmed	Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure.	GLDC MTHFR	8.69e-06	2	103	2	29141214
Pubmed	Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and Autism-Related Behaviors in Mice.	CHD8 ARID1B	8.69e-06	2	103	2	28867767
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLI1 KIF18A HIVEP1 PPP1R3B SOX7 ARID1B PELP1 ZNF587 MACF1 DCP1A	1.07e-05	591	103	10	15231748
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	HIVEP1 PPP1R3B ZNF711 TOMM70 ARID1B MACF1 PAX7 LONRF3 ZNF417	1.77e-05	497	103	9	23414517
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MYO9B PPP1R3B MTG2 CHD8 ICE1 INO80 TNRC6C MED13L FASN MTHFR ZNF335 RBM38 AHNAK2	2.38e-05	1105	103	13	35748872
Pubmed	Linc-MYH configures INO80 to regulate muscle stem cell numbers and skeletal muscle hypertrophy.	INO80 PAX7	2.60e-05	3	103	2	32960481
Pubmed	A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.	MAP2K4 ELK1	2.60e-05	3	103	2	23582328
Pubmed	Temporal recruitment of the mSin3A-histone deacetylase corepressor complex to the ETS domain transcription factor Elk-1.	SIN3A ELK1	2.60e-05	3	103	2	11283259
Pubmed	The mechanism of complex formation between Fli-1 and SRF transcription factors.	FLI1 ELK1	2.60e-05	3	103	2	10606656
Pubmed	Nrf2 deficiency promotes apoptosis and impairs PAX7/MyoD expression in aging skeletal muscle cells.	NFE2L2 PAX7	2.60e-05	3	103	2	24613379
Pubmed	Leukemia-related transcription factor TEL accelerates differentiation of Friend erythroleukemia cells.	FLI1 SIN3A	2.60e-05	3	103	2	12527908
Pubmed	Hyperhomocysteinemia-induced death of retinal ganglion cells: The role of Müller glial cells and NRF2.	MTHFR NFE2L2	2.60e-05	3	103	2	31026769
Pubmed	Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.	NFE2L3 NFE2L2	2.60e-05	3	103	2	15060151
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	CUX2 TGIF2 HIVEP1 MKRN2 ZNF318 HMG20B CITED2 SOX7 NFE2L2 BRPF1 ELK1	2.85e-05	808	103	11	20412781
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MYBBP1A TCOF1 CHD8 ZNF318 SIN3A FASN ARID1B PHACTR4 DCP1A	3.84e-05	549	103	9	38280479
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ASXL1 ZNF536 KIF27 MYO9B SIN3A HMG20B TOMM70 FASN PELP1 DCP1A KIF22	4.85e-05	857	103	11	25609649
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	MYBBP1A MIA3 TCOF1 CHD8 ZNF318 ARID1B PELP1 USP54	5.13e-05	440	103	8	34244565
Pubmed	FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements.	FLI1 ELK1	5.19e-05	4	103	2	9010223
Pubmed	Differential and overlapping targets of the transcriptional regulators NRF1, NRF2, and NRF3 in human cells.	NFE2L3 NFE2L2	5.19e-05	4	103	2	31628195
Pubmed	AC3-33, a novel secretory protein, inhibits Elk1 transcriptional activity via ERK pathway.	C3orf33 ELK1	5.19e-05	4	103	2	20680465
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	MYBBP1A MIA3 TCOF1 CHD8 SIN3A ZNF711 CITED2 FASN ARID1B PELP1 FHOD1 AUTS2 ZNF417	5.69e-05	1203	103	13	29180619
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	ASXL1 MYO9B CHD8 FASN BRPF1 MACF1 AHNAK2	6.13e-05	332	103	7	37433992
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1A MYBBP1A HIVEP1 YTHDF1 NFE2L2 PHACTR4	7.05e-05	233	103	6	37704626
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYBBP1A FER1L6 PELP1 ZNF335 BRPF1 MACF1	7.22e-05	234	103	6	36243803
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	CRTC3 MAN2B2 RADX MKRN2 ZNF318 TNRC6C DDX10 TOMM70 USP54 DCP1A	8.32e-05	754	103	10	33060197
Pubmed	Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3.	NFE2L3 NFE2L2	8.64e-05	5	103	2	10037736
Pubmed	Natural antioxidants exhibit chemopreventive characteristics through the regulation of CNC b-Zip transcription factors in estrogen-induced breast carcinogenesis.	NFE2L3 NFE2L2	8.64e-05	5	103	2	25130429
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	KIF18A MYBBP1A MYO9B RADX SIN3A DDX10 C18orf21 PELP1 MACF1 KIF22	8.78e-05	759	103	10	35915203
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	MAP2K4 MIA3 TCOF1 SCYL1 MACF1 DCP1A AHNAK2	1.02e-04	360	103	7	33111431
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	PRUNE2 MYBBP1A AFF3 FASN SPATS2L MACF1 LONRF3 KIF22	1.18e-04	496	103	8	31343991
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	MYBBP1A HIVEP1 CHD8 ICE1 ZNF318 DDX10 ZNF711 YTHDF1 ARID1B MED19 PELP1	1.25e-04	954	103	11	36373674
Pubmed	Genetic mouse models of autism spectrum disorder present subtle heterogenous cardiac abnormalities.	CHD8 ARID1B	1.29e-04	6	103	2	35445787
Pubmed	c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells.	FLI1 ELK1	1.29e-04	6	103	2	11313879
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MIA3 RADX ZNF318 MACF1 USP54 AHNAK2	1.37e-04	263	103	6	34702444
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	MYBBP1A TCOF1 RADX MKRN2 DDX10 YTHDF1 FASN SPATS2L MACF1 RBM38	1.45e-04	807	103	10	22681889
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	CRTC3 MYBBP1A TCOF1 SIN3A HMG20B FASN C18orf21 CARNMT1 USP54	1.47e-04	655	103	9	35819319
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	HIVEP1 CHD8 SIN3A MED13L HMG20B ARID1B	1.52e-04	268	103	6	33640491
Pubmed	DNA Damage Regulates Translation through β-TRCP Targeting of CReP.	HIVEP1 MED13L NFE2L2	1.54e-04	35	103	3	26091241
Pubmed	The DNA sequence and comparative analysis of human chromosome 20.	ASXL1 TGIF2 MTG2 DNAAF9 YTHDF1 NOL4L ZNF335 RBM38	1.56e-04	517	103	8	11780052
Pubmed	A multipotent progenitor domain guides pancreatic organogenesis.	TGIF2 SIN3A NFE2L2 BRPF1	1.59e-04	91	103	4	17609113
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	MYBBP1A TCOF1 CHD8 ZNF318 SIN3A DDX10	1.61e-04	271	103	6	32433965
Pubmed	Identification of host proteins required for HIV infection through a functional genomic screen.	CRTC3 ZNF536 MKRN2 DDX10 TOMM70 SPATS2L	1.64e-04	272	103	6	18187620
Pubmed	Androgen upregulates NR4A1 via the TFAP2A and ETS signaling networks.	FLI1 ELK1	1.81e-04	7	103	2	31146003
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	MYBBP1A MYO9B CHD8 INO80 DDX10 ZNF711 MED19 PELP1	1.92e-04	533	103	8	30554943
Pubmed	Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).	MAP2K4 ADRA1A PAX7	1.97e-04	38	103	3	22952603
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	CRTC3 MYO9B ZNF318 YTHDF1 TOMM70 FASN SPATS2L PELP1 MACF1 TNS4	2.08e-04	844	103	10	25963833
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ASXL1 ZNF536 TNRC6C MED13L TOMM70 NAV3 MACF1	2.16e-04	407	103	7	12693553
Pubmed	FBXL6 degrades phosphorylated p53 to promote tumor growth.	MYBBP1A FASN	2.40e-04	8	103	2	33568778
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CRTC3 HIVEP1 PAK6 NDRG1 PHACTR4 MACF1 USP54 DCP1A OTOG AHNAK2	2.43e-04	861	103	10	36931259
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ASXL1 MAN2B2 ICE1 NAV3	2.47e-04	102	103	4	10231032
Pubmed	TBR1 regulates autism risk genes in the developing neocortex.	CHD8 ARID1B	3.08e-04	9	103	2	27325115
Pubmed	The Sin3a repressor complex is a master regulator of STAT transcriptional activity.	TGIF2 SIN3A	3.08e-04	9	103	2	22783022
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	TCOF1 CHD8 YTHDF1 MACF1 ARHGAP20	3.09e-04	197	103	5	20811636
Pubmed	Knockout mice with pituitary malformations help identify human cases of hypopituitarism.	ASXL1 ARID1B GLDC	3.27e-04	45	103	3	38822427
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	MYBBP1A TCOF1 FASN PELP1 USP54	3.47e-04	202	103	5	24639526
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	KIF18A SDE2 CHD8 ZNF318 FHOD1 DCP1A AHNAK2	3.64e-04	444	103	7	34795231
Pubmed	A census of human transcription factors: function, expression and evolution.	FLI1 CUX2 HIVEP1 ZNF711 NFE2L3 SOX7 NFE2L2 ZNF335 ELK1 PAX7	3.70e-04	908	103	10	19274049
Pubmed	A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substrates.	MAP2K4 ELK1	3.85e-04	10	103	2	12788955
Pubmed	Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells.	CUX2 TCOF1	3.85e-04	10	103	2	22479190
Pubmed	PAK4 kinase is essential for embryonic viability and for proper neuronal development.	PAK6 PAX7	3.85e-04	10	103	2	14517283
Pubmed	PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways.	TCOF1 NDRG1	3.85e-04	10	103	2	24788519
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	KIF18A ZNF536 HIVEP1 CHD8	4.03e-04	116	103	4	30804394
Pubmed	Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.	PCDHA13 PCDHA11	4.69e-04	11	103	2	9655502
Pubmed	Interacting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinases.	MAP2K4 ELK1	4.69e-04	11	103	2	16533805
Pubmed	Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex.	KIF18A KIF22	4.69e-04	11	103	2	29229923
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	MYBBP1A CHD8 ZNF318 SIN3A DDX10 ARID1B	5.31e-04	339	103	6	30415952
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1A MYBBP1A CHD8 INO80 SPATS2L NAV3 DCP1A	5.44e-04	475	103	7	31040226
Pubmed	Genome-wide atlas of gene expression in the adult mouse brain.	CUX2 FOXB2 PAX7	5.61e-04	54	103	3	17151600
Pubmed	Identification of candidate proteins binding to prion protein.	MTHFR NFE2L2	5.62e-04	12	103	2	9173930
Pubmed	Proteins of the CNR family are multiple receptors for Reelin.	PCDHA13 PCDHA11	5.62e-04	12	103	2	10612399
Pubmed	A human MAP kinase interactome.	CRTC3 HIVEP1 CHD8 PAK6 FHOD1 NAV3 MACF1	6.23e-04	486	103	7	20936779
Pubmed	Homologs of genes expressed in Caenorhabditis elegans GABAergic neurons are also found in the developing mouse forebrain.	CUX2 FOXB2 PAX7	6.57e-04	57	103	3	21122108
Pubmed	Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2.	FASN NFE2L2	6.63e-04	13	103	2	36421460
Pubmed	MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.	FLI1 MED13L	6.63e-04	13	103	2	27570068
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	MYBBP1A MIA3 CHD8 TOMM70 FASN ARID1B BRPF1 MACF1 AHNAK2	6.71e-04	807	103	9	30575818
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	FHOD1 MACF1 REPS2 DCP1A	6.74e-04	133	103	4	15604093
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYBBP1A TCOF1 CHD8 ZNF318 DDX10 FASN PELP1 MACF1	7.37e-04	653	103	8	22586326
Pubmed	AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication.	CACNA1A AUTS2	7.72e-04	14	103	2	33305180
Pubmed	A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation.	NFE2L2 BRPF1 ELK1	8.01e-04	61	103	3	32911434
Pubmed	Seventy-five genetic loci influencing the human red blood cell.	CITED2 RBM38 KIF22	8.40e-04	62	103	3	23222517
Pubmed	TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.	MYBBP1A PELP1	8.89e-04	15	103	2	19321449
Pubmed	Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control.	SIN3A ARID1B	8.89e-04	15	103	2	17255939
Interaction	AR interactions	CDC42BPG ASXL1 MYBBP1A HIVEP1 CHD8 ZNF318 SIN3A PAK6 MED13L HMG20B ARID1B MLH3 SPATS2L NDRG1 PELP1 TNS4 USP54 REPS2	1.92e-06	992	101	18	int:AR
Interaction	GSC interactions	FLI1 ZNF536 HIVEP1 HMG20B ARID1B AUTS2	4.96e-06	87	101	6	int:GSC
Interaction	PHF21A interactions	ZNF536 LURAP1 HIVEP1 CHD8 ICE1 ZNF318 HMG20B SOX7 DCP1A KIF22	8.72e-06	343	101	10	int:PHF21A
Interaction	TGIF2 interactions	TGIF2 MKRN2 SIN3A FASN	1.47e-05	30	101	4	int:TGIF2
Interaction	GCM1 interactions	ZNF536 HIVEP1 HMG20B YTHDF1 ARID1B	2.32e-05	68	101	5	int:GCM1
Interaction	SMG7 interactions	HIVEP1 MKRN2 CHD8 ZNF318 TNRC6C YTHDF1 FASN ARID1B DCP1A	3.25e-05	319	101	9	int:SMG7
Interaction	HNF1B interactions	ZNF536 HIVEP1 TCOF1 HMG20B ARID1B PAX7 USP54	4.83e-05	190	101	7	int:HNF1B
Cytoband	9q21.2	PRUNE2 FOXB2	2.22e-04	10	103	2	9q21.2
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF18A KIF27 KIF22	5.76e-04	46	64	3	622
Coexpression	GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	CRTC3 SDE2 HIVEP1 ICE1 INO80 MED13L MED19 ZNF335	1.18e-06	198	103	8	M4247
ToppCell	TCGA-Prostate-Solid_Tissue_Normal-Prostate_normal_tissue-Prostate_normal_tissue-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	LURAP1 DNAAF9 ADRA1A ARHGAP20 NYAP1 PHYHIPL	2.91e-06	171	103	6	cafcb7714110cb361808dbe4b9a4963bb71f5129
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCOF1 HLA-DMB AFF3 ZNF318 MED19 AUTS2	5.17e-06	189	103	6	b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ASXL1 TCOF1 HLA-DMB AFF3 ARID1B RBM38	5.83e-06	193	103	6	bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCell	Control-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCOF1 HLA-DMB AFF3 ARID1B AUTS2 RBM38	6.56e-06	197	103	6	925bf0d38e4ce279fa45f455546ebd199282c0df
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 CRTC3 ZNF536 SLC38A9 DCP1A	3.86e-05	163	103	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NMNAT3 P3H2 AUTS2 PHYHIPL	4.71e-05	170	103	5	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CUX2 HLA-DMB AFF3 P3H2 AHNAK2	4.85e-05	171	103	5	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CUX2 HLA-DMB AFF3 P3H2 AHNAK2	4.85e-05	171	103	5	debbb071d260639b16269c94d172766908325c58
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM253 NMNAT3 MTHFR TNS4 KIF22	5.26e-05	174	103	5	7565f6d1c743809807d248ab0e098a2474d9c5b9
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MICAL1 MAP2K4 P3H2 TNS4 KIF22	5.26e-05	174	103	5	09b091e24317c3f7bac043f04762a533e30793de
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	5.26e-05	174	103	5	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	IPF-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	5.41e-05	175	103	5	a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICE1 TOMM70 NOL4L MACF1 CARNMT1	5.71e-05	177	103	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ICE1 TOMM70 NOL4L MACF1 CARNMT1	5.71e-05	177	103	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	Control-Myeloid-pDC\|Control / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	5.71e-05	177	103	5	3940663bb5b45b2ca9f772550380a516c53e410b
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	ICE1 TOMM70 NOL4L MACF1 CARNMT1	5.71e-05	177	103	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ICE1 TOMM70 NOL4L MACF1 CARNMT1	5.71e-05	177	103	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ICE1 TOMM70 NOL4L MACF1 CARNMT1	5.71e-05	177	103	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	5.71e-05	177	103	5	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	IPF-Myeloid-pDC\|IPF / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	5.86e-05	178	103	5	8d9e28492e1f157bac3308aa947fd864ca16d277
ToppCell	Control-Myeloid-pDC\|World / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	5.86e-05	178	103	5	20ef63d925e67ddd5955832312ca8574a6f838a4
ToppCell	COPD-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	6.02e-05	179	103	5	29b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell	IPF-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	ENTPD7 CUX2 HIVEP1 AFF3 AUTS2	6.18e-05	180	103	5	0f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ASXL1 MTG2 YTHDF1 NOL4L ZNF335	6.18e-05	180	103	5	c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCell	3'_v3-blood-Myeloid_Dendritic-pDC\|blood / Manually curated celltypes from each tissue	CUX2 HIVEP1 AFF3 ZNF711 P3H2	6.34e-05	181	103	5	66d890a105f955dca91d6e5e6c730d1a68ee9233
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ZNF536 AFF3 TMEM253 FAM135B PRKG2	6.34e-05	181	103	5	88f6f56f5f58b479d5db91b32c45934c045f88ea
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	AFF3 FASN P3H2 AUTS2 USP54	6.68e-05	183	103	5	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	ICE1 TOMM70 NOL4L MACF1 CARNMT1	6.68e-05	183	103	5	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B SPATS2L GLDC PHACTR4 PHYHIPL	7.22e-05	186	103	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1B SPATS2L GLDC PHACTR4 PHYHIPL	7.22e-05	186	103	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	AFF3 FASN P3H2 AUTS2 LONRF3	7.40e-05	187	103	5	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	normal_Lung-Myeloid_cells-pDCs\|normal_Lung / Location, Cell class and cell subclass	ENTPD7 MICAL1 HIVEP1 ARID1B P3H2	7.40e-05	187	103	5	d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCOF1 HLA-DMB AFF3 ZNF318 ARID1B	7.59e-05	188	103	5	d8decd9b5967873ca8320c2f9f07365f163c777f
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MIA3 HLA-DMB DNAAF9 PRKG2	7.59e-05	188	103	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RADX NOL4L LONRF3 REPS2	7.78e-05	189	103	5	98f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RADX NOL4L LONRF3 REPS2	7.78e-05	189	103	5	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCOF1 HLA-DMB AFF3 ARID1B RBM38	7.98e-05	190	103	5	0724665ac8238f2383c3a929d89abf4a48ec2420
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	AFF3 FASN P3H2 AUTS2 USP54	8.18e-05	191	103	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCOF1 HLA-DMB AFF3 ARID1B RBM38	8.38e-05	192	103	5	446c61c0d6ba89c619efe87ee495951299953981
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ASXL1 HIVEP1 MED13L ARID1B NDRG1	8.38e-05	192	103	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ASXL1 HIVEP1 MED13L ARID1B NDRG1	8.59e-05	193	103	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCOF1 HLA-DMB AFF3 ARID1B RBM38	8.59e-05	193	103	5	f4135615ee0118eec9e221becdd67888e0c2a112
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCOF1 HLA-DMB AFF3 AUTS2 RBM38	8.80e-05	194	103	5	5cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	AFF3 FASN P3H2 AUTS2 USP54	8.80e-05	194	103	5	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	Control-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	AFF3 FASN P3H2 AUTS2 MACF1	8.80e-05	194	103	5	a01de094f7bfd099bcbb2f94224690a2efb887b4
ToppCell	Control-B_naive-8\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCOF1 AFF3 ARID1B AUTS2 RBM38	9.23e-05	196	103	5	54074da84000e4749ade8acc542f05a275bf829f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ASXL1 AFF3 NMNAT3 ARID1B RBM38	9.23e-05	196	103	5	c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCell	Sepsis-ICU-SEP-Myeloid-cDC1\|ICU-SEP / Disease, condition lineage and cell class	HLA-DMB ZNF318 ZNF711 SOX7 SPATS2L	9.46e-05	197	103	5	e3174e90ea6136f1aa3a4a185b86458e35d51fd4
ToppCell	Control-B_naive-2\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TCOF1 HLA-DMB AFF3 AUTS2 RBM38	9.69e-05	198	103	5	b9aab1c2a0aeb5f95d24b321fe460bbab9e4e8a1
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZNF536 CUX2 ADRA1A AUTS2	1.02e-04	200	103	5	f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZNF536 CUX2 ADRA1A AUTS2	1.02e-04	200	103	5	70a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-CALB1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZNF536 CUX2 ADRA1A AUTS2	1.02e-04	200	103	5	1639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Cortical_neuron\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1A CUX2 AFF3 NDRG1 AUTS2	1.02e-04	200	103	5	5b3df61ff421846ef4cabf1bd5355534c8b95509
Disease	Gastrointestinal Diseases	CHD8 MTHFR NFE2L2	8.13e-06	12	100	3	C0017178
Disease	Functional Gastrointestinal Disorders	CHD8 MTHFR NFE2L2	8.13e-06	12	100	3	C0559031
Disease	Cholera Infantum	CHD8 MTHFR NFE2L2	8.13e-06	12	100	3	C1565321
Disease	alcohol drinking	CUX2 ICE1 INO80 AUTS2 RBM38	8.44e-06	81	100	5	EFO_0004329
Disease	Malignant neoplasm of breast	MICAL1 MAP2K4 ZNF318 DDX10 FASN ARID1B ADRA1A NDRG1 MTHFR P3H2 MACF1 USP54 LONRF3 REPS2	1.58e-05	1074	100	14	C0006142
Disease	dextro-looped transposition of the great arteries (is_implicated_in)	MED13L MTHFR	3.40e-05	3	100	2	DOID:0060770 (is_implicated_in)
Disease	Headache	DDX10 NFE2L3 NOL4L MACF1	6.75e-05	64	100	4	HP_0002315
Disease	testosterone measurement	KIF18A ZNF536 CUX2 MIA3 KIF27 MYO9B ZNF318 SIN3A FASN ARID1B NFE2L2 P3H2 AUTS2 MACF1	1.01e-04	1275	100	14	EFO_0004908
Disease	Intellectual Disability	CUX2 AFF3 CHD8 SIN3A MED13L FASN ZNF335 MACF1	1.44e-04	447	100	8	C3714756
Disease	migraine with aura (is_implicated_in)	CACNA1A MTHFR	1.69e-04	6	100	2	DOID:10024 (is_implicated_in)
Disease	hereditary ataxia (implicated_via_orthology)	CACNA1A SCYL1	2.36e-04	7	100	2	DOID:0050951 (implicated_via_orthology)
Disease	clear cell renal cell carcinoma (is_implicated_in)	PAK6 MTHFR	3.14e-04	8	100	2	DOID:4467 (is_implicated_in)
Disease	AUTISM, SUSCEPTIBILITY TO, 15	SIN3A AUTS2	3.14e-04	8	100	2	C2677504
Disease	migraine (is_implicated_in)	CACNA1A MTHFR	4.03e-04	9	100	2	DOID:6364 (is_implicated_in)
Disease	pathological myopia	FLI1 ZNF536 PPP1R3B NAV3	5.63e-04	111	100	4	EFO_0004207
Disease	Seizures	CUX2 AFF3 GLDC MTHFR MACF1	8.96e-04	218	100	5	C0036572
Disease	Agents acting on the renin-angiotensin system use measurement	MIA3 MYO9B ZNF318 INO80 SOX7 AUTS2	9.98e-04	335	100	6	EFO_0009931
Disease	Endometrial Neoplasms	MLH3 MTHFR NFE2L2	1.02e-03	58	100	3	C0014170
Disease	Profound Mental Retardation	CHD8 SIN3A MED13L FASN	1.30e-03	139	100	4	C0020796
Disease	Mental Retardation, Psychosocial	CHD8 SIN3A MED13L FASN	1.30e-03	139	100	4	C0025363
Disease	Mental deficiency	CHD8 SIN3A MED13L FASN	1.30e-03	139	100	4	C0917816
Disease	syndromic intellectual disability (implicated_via_orthology)	BRPF1 AUTS2	1.32e-03	16	100	2	DOID:0050888 (implicated_via_orthology)
Disease	cortical thickness	ZNF536 PPP1R3B ZNF318 DNAAF9 NOL4L ARID1B MTHFR NAV3 AUTS2 MACF1 PAX7	1.38e-03	1113	100	11	EFO_0004840
Disease	reaction time measurement	CUX2 KIF27 TNRC6C MED13L ADRA1A SPATS2L AUTS2 DNAI4	1.81e-03	658	100	8	EFO_0008393
Disease	Endometrial Carcinoma	MLH3 MTHFR NFE2L2	1.90e-03	72	100	3	C0476089
Disease	albumin:globulin ratio measurement	FLI1 AFF3 CITED2	1.98e-03	73	100	3	EFO_0005128
Disease	Antihypertensive use measurement	MYO9B ZNF318 INO80 PHACTR4 AUTS2	2.12e-03	265	100	5	EFO_0009927
Disease	smoking status measurement, diastolic blood pressure	ZNF318 SOX7 ARID1B MTHFR	2.13e-03	159	100	4	EFO_0006336, EFO_0006527
Disease	Left Ventricle Remodeling	ADRA1A NFE2L2	2.29e-03	21	100	2	C0600520
Disease	Ventricular Remodeling	ADRA1A NFE2L2	2.29e-03	21	100	2	C0600519
Disease	Colorectal Carcinoma	TCOF1 FRMPD2 ASAP3 PAK6 MLH3 MTHFR NPAP1 TNS4	2.69e-03	702	100	8	C0009402
Disease	beverage consumption measurement	HIVEP1 MKRN2 SPATS2L	2.85e-03	83	100	3	EFO_0010088
Disease	cleft lip	ZNF536 ICE1 ZNF318 P3H2 PAX7	2.85e-03	284	100	5	EFO_0003959
Disease	Carcinoma, Pancreatic Ductal	NDRG1 NFE2L2	2.99e-03	24	100	2	C0887833
Disease	cognitive function measurement	MAP2K4 ZNF536 HIVEP1 AFF3 FAM135B NOL4L ARID1B ADRA1A SPATS2L ZNF335 AUTS2 DNAI4	3.35e-03	1434	100	12	EFO_0008354

Protein segments in the cluster

Peptide	Gene	Start	Entry
QERPPAMAAKHSSSG	AFF3	196	P51826
GHAGLPQSPAKMGNS	CACNA1A	1086	O00555
NDSAGNMIISHKPPS	CEACAM18	66	A8MTB9
MEAQLPSHGGPKPSA	ASAP3	506	Q8TDY4
SAPHSGGKTGMEENR	CHD8	436	Q9HCK8
MDTAGQAGGHAASSP	ELK1	291	P19419
HSLPPGSNFSMTAGD	CARNMT1	281	Q8N4J0
IHRKNAPAGGSGMAS	ADRA1A	236	P35348
SFVPGNDAEMSKHPG	ARID1B	2026	Q8NFD5
NASASPPSGCPMHEG	HCCS	16	P53701
SPTADMAGALHPSAK	CUX2	1436	O14529
MPSGSQDKSAPSGHK	DCP1A	201	Q9NPI6
GTGQALDSHPTMKDP	ASXL1	826	Q8IXJ9
AAGGAVGTMAHSVPS	MKRN2	61	Q9H000
SPAPGHPAVSSMQGK	MAP2K4	26	P45985
RPLAAPGAMHGSQKD	RBM38	16	Q9H0Z9
GNPKNLHMTSSLAPD	INO80	1526	Q9ULG1
KTIHTASETNGMGPP	CDC42BPG	586	Q6DT37
PSTMHQGGLAAAAAA	PAX7	331	P23759
MSGESGQPEAGPSHA	RADX	1	Q6NSI4
ATDKGTPPMAGHCTV	PCDHA11	321	Q9Y5I1
HPAGDPGSDKETSSM	MTHFR	96	P42898
ASPPTGTNRHGMKAA	PAK6	206	Q9NQU5
PSHPGKMQEAAAVAA	FOXB2	211	Q5VYV0
HSTPVPDGKNAMSIF	MED13L	761	Q71F56
SEAQRGKTMPPGSHS	PSMG3-AS1	211	Q96PY0
KPGISAMADTPEHAS	ENTPD7	131	Q9NQZ7
GAGKTHTMLGSADEP	KIF18A	116	Q8NI77
PPSGHMLGNENKTET	KIF27	1311	Q86VH2
GGPGHSKMTEPSLQN	MLH3	446	Q9UHC1
AGKTHTMLGSPEQPG	KIF22	131	Q14807
PNSGAAGNSAGPKSM	NDRG1	376	Q92597
LPHNAGDCGSASMKP	NAV3	1746	Q8IVL0
NGPKTPVHSSGDMVQ	NFE2L2	391	Q16236
PLPGSISDGMNSSAH	NFE2L3	286	Q9Y4A8
NPSVTPNSMFGHKDG	AUTS2	766	Q8WXX7
PGASSTGHDLGDKIM	LURAP1	46	Q96LR2
FKSMAHSPGPVSQAS	MICAL1	611	Q8TDZ2
MISFSSGGENPHGVK	P3H2	641	Q8IVL5
HSNGPTDLSMKGGAS	NOL4L	361	Q96MY1
VGEAMAPPSHRKGDS	PELP1	501	Q8IZL8
GKPSDAMLKNGHTTP	PHACTR4	96	Q8IZ21
VHMQGGSPLQASPDK	PRKG2	86	Q13237
ENMHKGGSSPETLPS	MACF1	3906	Q9UPN3
KAGTDPSHMPTGPQA	MYBBP1A	951	Q9BQG0
GEGPHKTDLMAFSPS	PCDHA13	761	Q9Y5I0
VMPHSSAHKTAQPNG	HLA-DMB	156	P28068
MMPGETHSAAPGTAA	ICE1	1	Q9Y2F5
MAASPGSGSANPRKF	CRTC3	1	Q6UUV7
SGPPVQSMHAGSKNN	FRMPD2	746	Q68DX3
AAHLPKADMTASGSP	FLI1	26	Q01543
STGPGGSFAKHMVAQ	DNAAF9	316	Q5TEA3
MAGQPAATGSPSADK	C3orf33	1	Q6P1S2
QAPMAASSDAGPAGH	MAN2B2	461	Q9Y2E5
MTPGKHSGASARAAN	DNAI4	1	Q5VTH9
MGKTANSPGSGARPD	DDX10	1	Q13206
AEPSDMHSKSQGSPG	FAM135B	796	Q49AJ0
GPGRGDADSHASMKS	FHOD1	1041	Q9Y613
LIGSTKSNMGHPEPA	FASN	321	P49327
KSNMGHPEPASGLAA	FASN	326	P49327
EEAPSTSGMGFHAPK	SDE2	236	Q6IQ49
PSAGSGGHPDNSSMI	SLC38A9	256	Q8NBW4
NPNHDMSGSKGKSPA	C18orf21	146	Q32NC0
QGMTKPHSGPDLGIS	PPP1R3B	241	Q86XI6
KKNRHSPDHPGMGSS	MED19	221	A0JLT2
EKGEAGHSQPMGSPA	OTOG	1736	Q6ZRI0
HPSTKLSMVGPGSGA	NYAP1	121	Q6ZVC0
MSHGPKQPGAAAAPA	HMG20B	1	Q9P0W2
EAEMSSKGAGTNHPP	FER1L6	801	Q2WGJ9
DFSNASHVSGMPGPS	ARHGAP20	991	Q9P2F6
MQPSVKDNSGSHGSP	PHYHIPL	206	Q96FC7
LNTPGHPDSATGAMA	SOX7	336	Q9BT81
LHPSAGKSAMDSFPS	TNRC6C	1226	Q9HCJ0
GKSAMDSFPSHPQTP	TNRC6C	1231	Q9HCJ0
QKATDTGHMGPPQTH	PRUNE2	636	Q8WUY3
EASLGMKTPEAPAHS	SPATS2L	491	Q9NUQ6
EKDVHAASSPGMGGA	SCYL1	551	Q96KG9
SLGSAPLMGDDHPNA	MIA3	576	Q5JRA6
GNSMPHPATGKTVAN	TCOF1	136	Q13428
MKLSSAAGQESPGHP	GAS8-AS1	1	O95177
AMPQSSGSHGPAIAA	SIN3A	66	Q96ST3
HAGMVGFPNAGKSSL	MTG2	226	Q9H4K7
PTGHSMAAAPQGASN	NPAP1	1061	Q9NZP6
SMPLHSGQGEKPAAP	TGIF2	131	Q9GZN2
SKGLGPNMSSTPAHE	BRPF1	871	P55201
PSFGVSAPGKSMEAS	AHNAK2	3976	Q8IVF2
PSFGVSAPGKSMEAS	AHNAK2	4141	Q8IVF2
SGSGNMPASVAHVPA	CITED2	196	Q99967
SQDMGDAHKSPNMGP	TULP2	181	O00295
ASGPASAATMKPHPT	REPS2	586	Q8NFH8
ISIPCMGSKASSPHG	TNS4	231	Q8IZW8
DSETMHGPPFQEGKT	ZNF587	196	Q96SQ5
DSETMHGPPFQEGKT	ZNF417	196	Q8TAU3
SGHPEGPGAHLDMNS	TOMM70	96	O94826
LTEGAGSPMSSKHAG	nan	136	Q6ZVQ6
SPISSMAHGVPEGDK	ZNF536	471	O15090
MKTALGPAPTASSQH	TMEM253	116	P0C7T8
EHMGNTPLKIGSDGS	ZNF711	216	Q9Y462
APSSSGPGHLVAMGK	ZNF335	391	Q9H4Z2
KINSMGGDHPSFTSG	ZNF318	281	Q5VUA4
AAAEHSPQTAAGMPS	HIVEP1	2336	P15822
QPGFHSDTLSKAPGM	YTHDF1	166	Q9BYJ9
HGAPRPGMKSSPHDS	USP54	1276	Q70EL1
IPKSAHGTNPASAHM	GLDC	646	P23378
RGASAAQVDMGPHPK	LONRF3	26	Q496Y0
KAAGMSSPGAQSHPE	MYO9B	711	Q13459
MEGPDHGKALFSTPA	NMNAT3	111	Q96T66