Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	pyrimidine nucleotide transmembrane transporter activity	SLC25A33 SLC25A36	5.24e-05	2	145	2	GO:0015218
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR5P2 LPAR3 OR5AU1 OR10P1 INPP5K OR5AN1 DNER TMIGD3 LGR4 PLXND1 PTAFR F2R F2RL1 GFRA2 CHRNB1 OR8G2P GPR174 SCARB2 MTNR1A OR52E4 ROBO1 UNC5D OR5D13	1.14e-04	1353	145	23	GO:0004888
GeneOntologyMolecularFunction	G-protein alpha-subunit binding	LPAR3 RGS22 F2R F2RL1	2.64e-04	43	145	4	GO:0001965
GeneOntologyBiologicalProcess	cellular response to nitrogen compound	LGMN PSG4 PSG6 SLC25A33 INPP5K TSC2 PTAFR EZH2 GSK3A CHRNB1 NSG2 PTPRJ SPIDR FUT7 EP300 ZC3HAV1 SOS1	2.23e-05	752	145	17	GO:1901699
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 NOMO2 NOMO3	2.77e-05	9	145	3	GO:0160063
GeneOntologyBiologicalProcess	pyrimidine nucleotide import into mitochondrion	SLC25A33 SLC25A36	4.91e-05	2	145	2	GO:1990519
GeneOntologyBiologicalProcess	pyrimidine nucleotide transport	SLC25A33 SLC25A36	4.91e-05	2	145	2	GO:0006864
GeneOntologyBiologicalProcess	negative regulation of protein modification process	PSG4 PSG6 INPP5K TSC2 LRRK1 GFRA2 KLHL31 HIPK3 GPD1L PLAA PTPRJ P3H1 PPP1R15B	6.84e-05	512	145	13	GO:0031400
GeneOntologyBiologicalProcess	negative regulation of protein phosphorylation	PSG4 PSG6 INPP5K TSC2 LRRK1 GFRA2 KLHL31 HIPK3 GPD1L PTPRJ PPP1R15B	7.13e-05	375	145	11	GO:0001933
GeneOntologyBiologicalProcess	regulation of cell adhesion	MYF5 PSG4 PSG6 MYO10 ECM2 UNC13D MDGA2 TSC2 PLXND1 PTAFR RND1 PTPRJ JAG1 CCL5 FUT7 MDGA1 EP300 MEGF10	9.13e-05	927	145	18	GO:0030155
GeneOntologyBiologicalProcess	tissue remodeling	KLF6 SPP2 PSG4 PSG6 LGR4 EXT1 LRRK1 F2R JAG1	1.01e-04	262	145	9	GO:0048771
GeneOntologyBiologicalProcess	negative regulation of phosphorylation	PSG4 PSG6 INPP5K TSC2 LRRK1 GFRA2 KLHL31 HIPK3 GPD1L PTPRJ PPP1R15B	1.29e-04	401	145	11	GO:0042326
GeneOntologyBiologicalProcess	cellular response to insulin stimulus	PSG4 PSG6 SLC25A33 INPP5K TSC2 GSK3A PTPRJ FUT7 SOS1	1.31e-04	271	145	9	GO:0032869
GeneOntologyBiologicalProcess	negative regulation of glycogen (starch) synthase activity	INPP5K GSK3A	1.47e-04	3	145	2	GO:2000466
GeneOntologyBiologicalProcess	negative regulation of phosphorus metabolic process	PSG4 PSG6 INPP5K TSC2 LRRK1 GFRA2 GSK3A KLHL31 HIPK3 GPD1L PTPRJ PPP1R15B	1.52e-04	480	145	12	GO:0010563
GeneOntologyBiologicalProcess	response to insulin	PSG4 PSG6 SLC25A33 INPP5K TSC2 GSK3A SCAP PTPRJ FUT7 SOS1	1.57e-04	342	145	10	GO:0032868
GeneOntologyBiologicalProcess	cell junction organization	LGMN SDK2 PSG4 MYO9A PSG6 DNER MDGA2 TSC2 EXT1 PLXND1 F2R F2RL1 CHRNB1 PTPRJ SETD5 ROBO1 PKN2 MDGA1	1.69e-04	974	145	18	GO:0034330
GeneOntologyBiologicalProcess	positive regulation of Rho protein signal transduction	F2R F2RL1 GPR174 ROBO1	1.94e-04	41	145	4	GO:0035025
GeneOntologyBiologicalProcess	pseudopodium assembly	KLHL41 F2RL1 CCL5	2.15e-04	17	145	3	GO:0031269
GeneOntologyBiologicalProcess	response to nitrogen compound	LGMN PSG4 PSG6 SLC25A33 INPP5K TSC2 EXT1 PTAFR EZH2 ERLEC1 GSK3A CHRNB1 SCAP NSG2 PTPRJ JAG1 SPIDR FUT7 EP300 ZC3HAV1 SOS1	2.25e-04	1272	145	21	GO:1901698
GeneOntologyBiologicalProcess	neuron projection development	LPAR3 MYO9A FAT3 LGR4 LAMB3 TSC2 EXT1 PLXND1 EZH2 SPAG6 GSK3A NTN4 PLAA P3H1 SCARB2 ROBO1 CAMSAP2 UNC5D EP300 OTOG SOS1	2.58e-04	1285	145	21	GO:0031175
GeneOntologyBiologicalProcess	positive regulation of leukocyte migration	LGMN TMIGD3 PTAFR F2RL1 PTPRJ CCL5 FUT7	2.78e-04	179	145	7	GO:0002687
GeneOntologyBiologicalProcess	bone remodeling	SPP2 PSG4 PSG6 LGR4 EXT1 LRRK1	2.80e-04	127	145	6	GO:0046849
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR5P2 LPAR3 OR5AU1 OR10P1 INPP5K OR5AN1 ABHD6 TMIGD3 LGR4 PTAFR F2R F2RL1 GSK3A OR8G2P GPR174 NSG2 MTNR1A OR52E4 ROBO1 CAMKMT CCL5 OR5D13	2.98e-04	1395	145	22	GO:0007186
GeneOntologyBiologicalProcess	pseudopodium organization	KLHL41 F2RL1 CCL5	3.04e-04	19	145	3	GO:0031268
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 NOMO2 NOMO3	3.25e-05	9	155	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 NOMO2 NOMO3	1.37e-04	14	155	3	GO:0072379
Domain	DUF1220	NBPF11 NBPF1 NBPF15 NBPF9 NBPF14	1.21e-08	11	146	5	PF06758
Domain	NBPF_dom	NBPF11 NBPF1 NBPF15 NBPF9 NBPF14	1.21e-08	11	146	5	IPR010630
Domain	NBPF	NBPF11 NBPF1 NBPF15 NBPF9 NBPF14	1.21e-08	11	146	5	PS51316
Domain	DUF1220	NBPF11 NBPF1 NBPF15 NBPF9	4.38e-07	9	146	4	SM01148
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.86e-06	4	146	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.86e-06	4	146	3	IPR019008
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	2.55e-05	8	146	3	IPR013784
Domain	-	SDK2 PSG4 PSG6 TMIGD3 FNDC3A MDGA2 PLXND1 NOMO1 MFAP3 PTPRJ NOMO2 ROBO1 LRRN2 MDGA1 UNC5D NOMO3	6.36e-05	663	146	16	2.60.40.10
Domain	IGc2	SDK2 PSG4 PSG6 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	9.84e-05	235	146	9	SM00408
Domain	Ig_sub2	SDK2 PSG4 PSG6 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	9.84e-05	235	146	9	IPR003598
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	1.26e-04	13	146	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	1.26e-04	13	146	3	2.60.40.1120
Domain	Ig-like_fold	SDK2 PSG4 PSG6 TMIGD3 FNDC3A MDGA2 PLXND1 NOMO1 MFAP3 PTPRJ NOMO2 ROBO1 LRRN2 MDGA1 UNC5D NOMO3	1.32e-04	706	146	16	IPR013783
Domain	CarboxyPept-like_regulatory	NOMO1 NOMO2 NOMO3	2.94e-04	17	146	3	IPR008969
Domain	VWF_dom	ECM2 FCGBP JAG1 OTOG	3.18e-04	42	146	4	IPR001007
Domain	Protea_act_rcpt	F2R F2RL1	3.60e-04	4	146	2	IPR003912
Domain	VWC_out	FCGBP JAG1 OTOG	4.14e-04	19	146	3	SM00215
Domain	Ig_I-set	SDK2 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	7.45e-04	190	146	7	IPR013098
Domain	I-set	SDK2 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	7.45e-04	190	146	7	PF07679
Domain	ig	SDK2 PSG4 PSG6 MDGA2 MFAP3 MDGA1 UNC5D	7.45e-04	190	146	7	PF00047
Domain	Immunoglobulin	SDK2 PSG4 PSG6 MDGA2 MFAP3 MDGA1 UNC5D	7.45e-04	190	146	7	IPR013151
Domain	GPCR_Rhodpsn_7TM	OR5P2 LPAR3 OR5AU1 OR10P1 OR5AN1 LGR4 PTAFR F2R F2RL1 OR8G2P GPR174 MTNR1A OR52E4 OR5D13	7.86e-04	670	146	14	IPR017452
Domain	7tm_1	OR5P2 LPAR3 OR5AU1 OR10P1 OR5AN1 LGR4 PTAFR F2R F2RL1 OR8G2P GPR174 MTNR1A OR52E4 OR5D13	8.68e-04	677	146	14	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR5P2 LPAR3 OR5AU1 OR10P1 OR5AN1 LGR4 PTAFR F2R F2RL1 OR8G2P GPR174 MTNR1A OR52E4 OR5D13	9.72e-04	685	146	14	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR5P2 LPAR3 OR5AU1 OR10P1 OR5AN1 LGR4 PTAFR F2R F2RL1 OR8G2P GPR174 MTNR1A OR52E4 OR5D13	1.06e-03	691	146	14	PS50262
Domain	GPCR_Rhodpsn	OR5P2 LPAR3 OR5AU1 OR10P1 OR5AN1 LGR4 PTAFR F2R F2RL1 OR8G2P GPR174 MTNR1A OR52E4 OR5D13	1.07e-03	692	146	14	IPR000276
Domain	hEGF	DNER JAG1 MEGF10	1.33e-03	28	146	3	PF12661
Domain	VPS9	GAPVD1 VPS9D1	1.65e-03	8	146	2	SM00167
Domain	EGF_Lam	LAMB3 NTN4 MEGF10	2.55e-03	35	146	3	SM00180
Domain	Laminin_EGF	LAMB3 NTN4 MEGF10	2.55e-03	35	146	3	PF00053
Domain	VPS9	GAPVD1 VPS9D1	2.62e-03	10	146	2	PS51205
Domain	VPS9	GAPVD1 VPS9D1	2.62e-03	10	146	2	PF02204
Domain	VPS9	GAPVD1 VPS9D1	2.62e-03	10	146	2	IPR003123
Domain	RA	MYO9A MYO10 ARAP3	2.77e-03	36	146	3	PF00788
Domain	Fol_N	DNER FCGBP	3.19e-03	11	146	2	IPR003645
Domain	FOLN	DNER FCGBP	3.19e-03	11	146	2	SM00274
Domain	VWC	ECM2 FCGBP JAG1	3.23e-03	38	146	3	SM00214
Domain	Laminin_EGF	LAMB3 NTN4 MEGF10	3.23e-03	38	146	3	IPR002049
Domain	EGF-like_dom	PAMR1 FAT3 DNER FCGBP JAG1 MEGF10 OTOG	3.48e-03	249	146	7	IPR000742
Domain	RA_dom	MYO9A MYO10 ARAP3	3.74e-03	40	146	3	IPR000159
Domain	WWE	PARP11 ZC3HAV1	3.80e-03	12	146	2	PF02825
Domain	WWE-dom	PARP11 ZC3HAV1	3.80e-03	12	146	2	IPR004170
Domain	C8	FCGBP OTOG	3.80e-03	12	146	2	PF08742
Domain	WWE	PARP11 ZC3HAV1	3.80e-03	12	146	2	PS50918
Domain	TIL	FCGBP OTOG	3.80e-03	12	146	2	PF01826
Domain	EGF_1	PAMR1 FAT3 DNER LAMB3 NTN4 JAG1 MEGF10	3.96e-03	255	146	7	PS00022
Domain	SET	EZH2 SETDB1 SETD5	4.01e-03	41	146	3	PF00856
Domain	Unchr_dom_Cys-rich	FCGBP OTOG	4.47e-03	13	146	2	IPR014853
Domain	C8	FCGBP OTOG	4.47e-03	13	146	2	SM00832
Domain	EGF-like_CS	PAMR1 FAT3 DNER LAMB3 NTN4 JAG1 MEGF10	4.49e-03	261	146	7	IPR013032
Domain	FN3	SDK2 FNDC3A MDGA2 PTPRJ ROBO1 MDGA1	4.80e-03	199	146	6	PS50853
Domain	Rho_GTPase_activation_prot	GAPVD1 MYO9A PLXND1 ARAP3	5.03e-03	88	146	4	IPR008936
Domain	TIL_dom	FCGBP OTOG	5.19e-03	14	146	2	IPR002919
Domain	SET	EZH2 SETDB1 SETD5	5.56e-03	46	146	3	SM00317
Domain	IG	SDK2 PSG4 PSG6 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	5.92e-03	421	146	9	SM00409
Domain	Ig_sub	SDK2 PSG4 PSG6 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	5.92e-03	421	146	9	IPR003599
Domain	FN3_dom	SDK2 FNDC3A MDGA2 PTPRJ ROBO1 MDGA1	6.07e-03	209	146	6	IPR003961
Domain	Ig-like_dom	SDK2 PSG4 PSG6 TMIGD3 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	6.24e-03	503	146	10	IPR007110
Domain	VWF_type-D	FCGBP OTOG	6.78e-03	16	146	2	IPR001846
Domain	MAM_1	MDGA2 MDGA1	6.78e-03	16	146	2	PS00740
Domain	Laminin_N	LAMB3 NTN4	6.78e-03	16	146	2	IPR008211
Domain	VWFD	FCGBP OTOG	6.78e-03	16	146	2	PS51233
Domain	LamNT	LAMB3 NTN4	6.78e-03	16	146	2	SM00136
Domain	VWD	FCGBP OTOG	6.78e-03	16	146	2	SM00216
Domain	LAMININ_NTER	LAMB3 NTN4	6.78e-03	16	146	2	PS51117
Domain	Laminin_N	LAMB3 NTN4	6.78e-03	16	146	2	PF00055
Domain	VWD	FCGBP OTOG	6.78e-03	16	146	2	PF00094
Domain	SET_dom	EZH2 SETDB1 SETD5	7.01e-03	50	146	3	IPR001214
Domain	SET	EZH2 SETDB1 SETD5	7.01e-03	50	146	3	PS50280
Domain	Poly(ADP-ribose)pol_cat_dom	PARP11 ZC3HAV1	7.64e-03	17	146	2	IPR012317
Domain	PARP_CATALYTIC	PARP11 ZC3HAV1	7.64e-03	17	146	2	PS51059
Domain	PARP	PARP11 ZC3HAV1	7.64e-03	17	146	2	PF00644
Domain	-	PARP11 ZC3HAV1	7.64e-03	17	146	2	3.90.228.10
Domain	MAM	MDGA2 MDGA1	7.64e-03	17	146	2	SM00137
Domain	C345C	NTN4 PCOLCE	7.64e-03	17	146	2	SM00643
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF8 NBPF12 NBPF11 NBPF20 NBPF1 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14	9.48e-19	21	158	10	16079250
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF12 NBPF1 NBPF15 NBPF9 NBPF14	1.65e-12	10	158	6	22973535
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	LGMN NEMP1 TFPI2 DNER LGR4 LAMB3 NBPF26 PSMD2 TSC2 EXT1 PLXND1 ERLEC1 NOMO1 CNNM3 MYOF PIGT SCAP OAF PTPRJ NOMO2 P3H1 SCARB2 ROBO1 EPDR1 BACE2 DNMT1 PCOLCE	6.76e-12	1201	158	27	35696571
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	9.20e-08	3	158	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	9.20e-08	3	158	3	25576386
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	3.67e-07	4	158	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	3.67e-07	4	158	3	9267806
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF8 NBPF12 NBPF11 NBPF1 NBPF9 NBPF10 NBPF14 OTOG	1.19e-06	170	158	8	23314748
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	5.07e-06	8	158	3	15257293
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 NOMO2 NOMO3	7.57e-06	9	158	3	36261522
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	NEMP1 ABHD6 SRM BSDC1 PSMD2 FNDC3A ERLEC1 NOMO1 CNNM3 SCAP NOMO2 PPP1R15B SEC23IP ROBO1 NOMO3 ZC3HAV1	7.69e-06	952	158	16	38569033
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	LGMN LAMB3 ERLEC1 CNNM3 PIGT P3H1 EPDR1	1.07e-05	164	158	7	32409323
Pubmed	A KRAS-directed transcriptional silencing pathway that mediates the CpG island methylator phenotype.	EZH2 SETDB1 DNMT1	1.48e-05	11	158	3	24623306
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	1.48e-05	11	158	3	32820719
Pubmed	Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress.	INPP5K TRIM68 ERLEC1 PIGT P3H1 BACE2 ZC3HAV1	1.57e-05	174	158	7	32149426
Pubmed	Arginine-specific protease from Porphyromonas gingivalis activates protease-activated receptors on human oral epithelial cells and induces interleukin-6 secretion.	F2R F2RL1	2.05e-05	2	158	2	11447194
Pubmed	Expression of and functional responses to protease-activated receptors on human eosinophils.	F2R F2RL1	2.05e-05	2	158	2	12832443
Pubmed	Tissue factor pathway inhibitor-2 was repressed by CpG hypermethylation through inhibition of KLF6 binding in highly invasive breast cancer cells.	KLF6 TFPI2	2.05e-05	2	158	2	18053161
Pubmed	PH motifs in PAR1&2 endow breast cancer growth.	F2R F2RL1	2.05e-05	2	158	2	26600192
Pubmed	Proteinase-activated receptors 1 and 2 mediate contraction of human oesophageal muscularis mucosae.	F2R F2RL1	2.05e-05	2	158	2	19694963
Pubmed	Mold allergen, pen C 13, induces IL-8 expression in human airway epithelial cells by activating protease-activated receptor 1 and 2.	F2R F2RL1	2.05e-05	2	158	2	17404307
Pubmed	Roles of PAR1 and PAR2 in viral myocarditis.	F2R F2RL1	2.05e-05	2	158	2	24759133
Pubmed	The role of protease-activated receptor-1 in bone healing.	F2R F2RL1	2.05e-05	2	158	2	15743797
Pubmed	Involvement of PAR-2 in the Induction of Cell-Specific Matrix Metalloproteinase-2 by Activated Protein C in Cutaneous Wound Healing.	F2R F2RL1	2.05e-05	2	158	2	38203540
Pubmed	Critical role for PAR1 in kallikrein 6-mediated oligodendrogliopathy.	F2R F2RL1	2.05e-05	2	158	2	23832758
Pubmed	Cardiovascular responses mediated by protease-activated receptor-2 (PAR-2) and thrombin receptor (PAR-1) are distinguished in mice deficient in PAR-2 or PAR-1.	F2R F2RL1	2.05e-05	2	158	2	9918574
Pubmed	Protease-activated receptor-2 modulates protease-activated receptor-1-driven neointimal hyperplasia.	F2R F2RL1	2.05e-05	2	158	2	21940952
Pubmed	PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology.	F2R F2RL1	2.05e-05	2	158	2	20215560
Pubmed	DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.	EZH2 DNMT1	2.05e-05	2	158	2	25595591
Pubmed	Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells.	EZH2 DNMT1	2.05e-05	2	158	2	26362062
Pubmed	Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization.	MDGA2 MDGA1	2.05e-05	2	158	2	15019943
Pubmed	Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis.	F2R F2RL1	2.05e-05	2	158	2	25689283
Pubmed	Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder.	F2R F2RL1	2.05e-05	2	158	2	17431214
Pubmed	Protease-activated receptor signalling initiates α5β1-integrin-mediated adhesion in non-haematopoietic cells.	F2R F2RL1	2.05e-05	2	158	2	31959953
Pubmed	Conserved structure and adjacent location of the thrombin receptor and protease-activated receptor 2 genes define a protease-activated receptor gene cluster.	F2R F2RL1	2.05e-05	2	158	2	8784787
Pubmed	Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.	NBPF11 NBPF1	2.05e-05	2	158	2	7700633
Pubmed	Identification of the mitochondrial pyruvate carrier in Saccharomyces cerevisiae.	SLC25A33 SLC25A36	2.05e-05	2	158	2	12887330
Pubmed	Proteinase-activated receptors 1 and 2 exert opposite effects on renal renin release.	F2R F2RL1	2.05e-05	2	158	2	21859963
Pubmed	Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice.	F2R F2RL1	2.05e-05	2	158	2	18757438
Pubmed	House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1.	F2R F2RL1	2.05e-05	2	158	2	12370395
Pubmed	PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca2+ Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation.	F2R F2RL1	2.05e-05	2	158	2	30995477
Pubmed	Involvement of proteinase-activated receptors 1 and 2 in spreading and phagocytosis by murine adherent peritoneal cells: modulation by the C-terminal of S100A9 protein.	F2R F2RL1	2.05e-05	2	158	2	19941849
Pubmed	The thrombin receptor is a critical extracellular switch controlling myelination.	F2R F2RL1	2.05e-05	2	158	2	25628003
Pubmed	The possible role of EZH2 and DNMT1 polymorphisms in sporadic triple-negative breast carcinoma in southern Chinese females.	EZH2 DNMT1	2.05e-05	2	158	2	26162541
Pubmed	Phospholipid metabolite production in human urothelial cells after protease-activated receptor cleavage.	F2R F2RL1	2.05e-05	2	158	2	12372769
Pubmed	Protease-activated receptor (PAR)2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.	F2R F2RL1	2.05e-05	2	158	2	23637930
Pubmed	Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration.	F2R F2RL1	2.05e-05	2	158	2	18832729
Pubmed	The differential expression of protease activated receptors contributes to functional differences between dark and fair keratinocytes.	F2R F2RL1	2.05e-05	2	158	2	27979585
Pubmed	p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function.	HIPK2 EP300	2.05e-05	2	158	2	29170424
Pubmed	Proteinase-activated receptors-1 and 2 induce electrogenic Cl- secretion in the mouse cecum by distinct mechanisms.	F2R F2RL1	2.05e-05	2	158	2	20413722
Pubmed	Proteases in agricultural dust induce lung inflammation through PAR-1 and PAR-2 activation.	F2R F2RL1	2.05e-05	2	158	2	26092994
Pubmed	[Potential of proteinase-activated receptors as a novel target for treatment of pulmonary hypertension].	F2R F2RL1	2.05e-05	2	158	2	24717606
Pubmed	'Role reversal' for the receptor PAR1 in sepsis-induced vascular damage.	F2R F2RL1	2.05e-05	2	158	2	17965715
Pubmed	[Influence of mutations of proteinase-activated receptors F2R/PAR1 and F2RL1/PAR2 on inflammatory bowel disease].	F2R F2RL1	2.05e-05	2	158	2	19080851
Pubmed	Legumain Induces Oral Cancer Pain by Biased Agonism of Protease-Activated Receptor-2.	LGMN F2RL1	2.05e-05	2	158	2	33172978
Pubmed	Protease-activated-receptor-2 affects protease-activated-receptor-1-driven breast cancer.	F2R F2RL1	2.05e-05	2	158	2	24177339
Pubmed	Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms.	F2R F2RL1	2.05e-05	2	158	2	25200274
Pubmed	Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis.	F2R F2RL1	2.05e-05	2	158	2	15280447
Pubmed	The human SLC25A33 and SLC25A36 genes of solute carrier family 25 encode two mitochondrial pyrimidine nucleotide transporters.	SLC25A33 SLC25A36	2.05e-05	2	158	2	25320081
Pubmed	Protease-activated receptor 2, rather than protease-activated receptor 1, contributes to the aggressive properties of synovial fibroblasts in rheumatoid arthritis.	F2R F2RL1	2.05e-05	2	158	2	21905006
Pubmed	EZH2 enhances expression of CCL5 to promote recruitment of macrophages and invasion in lung cancer.	EZH2 CCL5	2.05e-05	2	158	2	31855281
Pubmed	Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells.	EZH2 DNMT1	2.05e-05	2	158	2	19279403
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DLGAP1 DNER PSMD2 TSC2 TRIM68 EYA3 GSK3A MPRIP VPS9D1 SETDB1 NOMO2 SEC23IP ROBO1 LRRN2 BACE2 EP300 DNMT1 SOS1	2.38e-05	1285	158	18	35914814
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	NBPF8 NBPF12 PSG6 NBPF11 ERLEC1 NBPF1 NBPF15 NBPF9 NBPF10 ADAMTS20 NBPF14	2.48e-05	513	158	11	25798074
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	NEMP1 GAPVD1 SRM PSMD2 FNDC3A TSC2 ERLEC1 GSK3A CNNM3 SCAP PLAA P3H1 SEC23IP NOMO3 DNMT1	2.80e-05	942	158	15	31073040
Pubmed	Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells.	F2R F2RL1	6.13e-05	3	158	2	11850418
Pubmed	Distinct roles of protease-activated receptors in signal transduction regulation of endothelial nitric oxide synthase.	F2R F2RL1	6.13e-05	3	158	2	19064814
Pubmed	Kallikrein-related peptidase 4 (KLK4) initiates intracellular signaling via protease-activated receptors (PARs). KLK4 and PAR-2 are co-expressed during prostate cancer progression.	F2R F2RL1	6.13e-05	3	158	2	18308730
Pubmed	Prognostic value of histone marks H3K27me3 and H3K9me3 and modifying enzymes EZH2, SETDB1 and LSD-1 in colorectal cancer.	EZH2 SETDB1	6.13e-05	3	158	2	30105513
Pubmed	Mitochondrial reactive oxygen species: a common pathway for PAR1- and PAR2-mediated tissue factor induction in human endothelial cells.	F2R F2RL1	6.13e-05	3	158	2	18983479
Pubmed	Expression of DNA methyltransferases 1 and 3B correlates with EZH2 and this 3-marker epigenetic signature predicts outcome in glioblastomas.	EZH2 DNMT1	6.13e-05	3	158	2	26892683
Pubmed	Enhancer of zeste homolog 2 promotes hepatocellular cancer progression and chemoresistance by enhancing protein kinase B activation through microRNA-381-mediated SET domain bifurcated 1.	EZH2 SETDB1	6.13e-05	3	158	2	35184652
Pubmed	Protease-activated receptors-1 and -2 can mediate endothelial barrier protection: role in factor Xa signaling.	F2R F2RL1	6.13e-05	3	158	2	16359518
Pubmed	Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells.	F2R F2RL1	6.13e-05	3	158	2	11907122
Pubmed	Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.	F2R F2RL1	6.13e-05	3	158	2	14576054
Pubmed	Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein.	F2R F2RL1	6.13e-05	3	158	2	23921961
Pubmed	Epigenetic regulation of autophagy by the methyltransferase EZH2 through an MTOR-dependent pathway.	TSC2 EZH2	6.13e-05	3	158	2	26735435
Pubmed	Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer.	EZH2 DNMT1	6.13e-05	3	158	2	26305882
Pubmed	Thrombin up-regulates tissue factor pathway inhibitor-2 synthesis through a cyclooxygenase-2-dependent, epidermal growth factor receptor-independent mechanism.	TFPI2 F2R	6.13e-05	3	158	2	14623891
Pubmed	Induction of IL-13 production and upregulated expression of protease activated receptor-1 by RANTES in a mast cell line.	F2R CCL5	6.13e-05	3	158	2	21074454
Pubmed	EZH2-DNMT1-mediated epigenetic silencing of miR-142-3p promotes metastasis through targeting ZEB2 in nasopharyngeal carcinoma.	EZH2 DNMT1	6.13e-05	3	158	2	30353102
Pubmed	Protease Activated Receptors 1 and 2 Correlate Differently with Breast Cancer Aggressiveness Depending on Tumor ER Status.	F2R F2RL1	6.13e-05	3	158	2	26244666
Pubmed	Thrombin receptor deficiency leads to a high bone mass phenotype by decreasing the RANKL/OPG ratio.	F2R F2RL1	6.13e-05	3	158	2	25460576
Pubmed	Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia.	F2R F2RL1	6.13e-05	3	158	2	17623652
Pubmed	Proteinase-activated receptor-1 (PAR(1)) and PAR(2) but not PAR(4) mediate contraction in human and guinea-pig gallbladders.	F2R F2RL1	6.13e-05	3	158	2	18179608
Pubmed	Protease-activated receptor mediated RhoA signaling and cytoskeletal reorganization in LNCaP cells.	F2R F2RL1	6.13e-05	3	158	2	12534282
Pubmed	Kallikrein-related peptidase 6 orchestrates astrocyte form and function through proteinase activated receptor-dependent mechanisms.	F2R F2RL1	6.13e-05	3	158	2	29604205
Pubmed	Overexpression of protease-activated receptors-1,-2, and-4 (PAR-1, -2, and -4) in prostate cancer.	F2R F2RL1	6.13e-05	3	158	2	17373694
Pubmed	Activation of Endogenous Retroviruses in Dnmt1(-/-) ESCs Involves Disruption of SETDB1-Mediated Repression by NP95 Binding to Hemimethylated DNA.	SETDB1 DNMT1	6.13e-05	3	158	2	27151458
Pubmed	DNMT1/miR-152-3p/SOS1 signaling axis promotes self-renewal and tumor growth of cancer stem-like cells derived from non-small cell lung cancer.	DNMT1 SOS1	6.13e-05	3	158	2	38622665
Pubmed	HOTAIR-mediated reciprocal regulation of EZH2 and DNMT1 contribute to polyphyllin I-inhibited growth of castration-resistant prostate cancer cells in vitro and in vivo.	EZH2 DNMT1	6.13e-05	3	158	2	29221985
Pubmed	p21(WAF1) negatively regulates DNMT1 expression in mammalian cells.	EP300 DNMT1	6.13e-05	3	158	2	19275888
Pubmed	Activation of proteinase-activated receptors induces itch-associated response through histamine-dependent and -independent pathways in mice.	F2R F2RL1	6.13e-05	3	158	2	18987429
Pubmed	Mapping cell type-specific transcriptional enhancers using high affinity, lineage-specific Ep300 bioChIP-seq.	MYF5 EP300	6.13e-05	3	158	2	28121289
Pubmed	Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling.	F2R F2RL1	6.13e-05	3	158	2	22407318
Pubmed	Regulation of transcription of the Dnmt1 gene by Sp1 and Sp3 zinc finger proteins.	EP300 DNMT1	6.13e-05	3	158	2	12071960
Pubmed	Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis.	F2R F2RL1	6.13e-05	3	158	2	17363687
Pubmed	Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis.	PTAFR F2R	6.13e-05	3	158	2	19703903
Pubmed	Thrombin receptors and protease-activated receptor-2 in human placentation: receptor activation mediates extravillous trophoblast invasion in vitro.	F2R F2RL1	6.13e-05	3	158	2	14507634
Pubmed	Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells.	F2R F2RL1	6.13e-05	3	158	2	12195707
Interaction	NCLN interactions	EZH2 F2RL1 NOMO1 PIGT RND1 NOMO2 RHOV EP300 NOMO3	5.76e-06	183	141	9	int:NCLN
Interaction	FBXO2 interactions	LGMN DLGAP1 SDK2 LAMB3 PLXND1 NOMO1 PIGT SCAP PTPRJ JAG1 ROBO1 EPDR1 NOMO3	6.52e-06	411	141	13	int:FBXO2
Cytoband	1q21.1	NBPF8 NBPF11 NBPF9 NBPF10 NBPF14	2.50e-06	62	158	5	1q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	NBPF12 NBPF11 NBPF20 NBPF19 SETDB1 NBPF15 NBPF9 NBPF10 NBPF14	1.23e-05	404	158	9	chr1q21
Cytoband	1q32.1	SLC26A9 PPP1R15B LRRN2 CAMSAP2	5.48e-04	108	158	4	1q32.1
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF12 NBPF26 NBPF11 NBPF20 NBPF1 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14	5.36e-19	23	115	11	662
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SDK2 MDGA2 MFAP3 ROBO1 LRRN2 MDGA1 UNC5D	7.63e-05	161	115	7	593
GeneFamily	F2R receptors	F2R F2RL1	2.39e-04	4	115	2	219
GeneFamily	VPS9 domain containing	GAPVD1 VPS9D1	1.75e-03	10	115	2	928
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MYO10 SH3BP2 MPRIP ARAP3 OSBPL11 SOS1	2.04e-03	206	115	6	682
GeneFamily	CD molecules\|V-set domain containing\|Pregnancy specific glycoproteins	PSG4 PSG6	2.12e-03	11	115	2	1315
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14 MEGF10	1.42e-09	187	158	10	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14 MEGF10	1.42e-09	187	158	10	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14 MEGF10	1.42e-09	187	158	10	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14 MEGF10	1.42e-09	187	158	10	93c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14 MEGF10	1.65e-09	190	158	10	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14 MEGF10	1.65e-09	190	158	10	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14	2.40e-08	187	158	9	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10 NBPF14	2.40e-08	187	158	9	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF14 MEGF10	2.76e-08	190	158	9	b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	KLF6 MYO10 SLC25A33 SH3BP2 LGR4 FNDC3A EVA1C AASS	3.93e-07	189	158	8	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	LPAR3 ECM2 F2R GFRA2 OAF LRRN2 BACE2 PCOLCE	4.09e-07	190	158	8	3aed03b87ba2c8d479048c3ceef3ff5e38746c28
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10	4.09e-07	190	158	8	5c64b727669b23d2a23c8ad1d5d6caab7af37d56
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10	4.43e-07	192	158	8	f7e4509003d71f805b9d4587098e90d2897b6739
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF NBPF14 MEGF10	4.43e-07	192	158	8	43beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Astro\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 NBPF26 RFX4 OAF AASS NBPF10	4.43e-07	192	158	8	705ce805cb00a53793b57bcf466d0fbec590a83c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRIM68 PTAFR GSK3A PRODH2 SLC25A36 RND1 MDGA1	1.94e-06	163	158	7	2d6fd2562d78be9f83fa35d811eb7e27eb8cc5d1
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 UNC13D CHRNB1 FCGBP RHOV JAG1 EPDR1	2.99e-06	174	158	7	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ZNF142 ECM2 LGR4 SLC26A9 CHRNB1 OAF RHOV	3.11e-06	175	158	7	085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 RGS22 MDGA2 ADAMTS20 ROBO1 UNC5D OTOG	4.32e-06	184	158	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 RGS22 MDGA2 ADAMTS20 ROBO1 UNC5D OTOG	4.32e-06	184	158	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 RGS22 MDGA2 ADAMTS20 ROBO1 UNC5D OTOG	4.32e-06	184	158	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 NBPF26 RFX4 OAF AASS NBPF10 NBPF14	4.64e-06	186	158	7	41e03be964044dae690d566bd078dab3d8045eba
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	PAMR1 ECM2 NBPF26 OAF P3H1 JAG1 PCOLCE	4.64e-06	186	158	7	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	PAMR1 ECM2 NBPF26 OAF P3H1 JAG1 PCOLCE	4.64e-06	186	158	7	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 MYO10 FAT3 TMEM132C MYOF PCOLCE	5.16e-06	189	158	7	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma-erythroid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	LGMN FAT3 TMIGD3 GFRA2 NTN4 FCGBP PCOLCE	5.34e-06	190	158	7	cf463b2f227f3cc7d3fd296c810c0cbe51cbee72
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	EXT1 NOMO1 MYOF RND1 PTPRJ NOMO2 NOMO3	5.53e-06	191	158	7	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	Control-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	EXT1 NOMO1 MYOF RND1 PTPRJ NOMO2 NOMO3	5.72e-06	192	158	7	7e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 NBPF26 RFX4 OAF NBPF14 MEGF10	5.92e-06	193	158	7	b03d908d4b8940927f72c76a1b0f237d13f39056
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 NBPF26 RFX4 OAF NBPF14 MEGF10	5.92e-06	193	158	7	40edc07b6e7f19f6ee885fa5af0b63ef1b0f2468
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP1 SDK2 MYO10 FAT3 EXT1 TMEM132C AASS	5.92e-06	193	158	7	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 FAT3 TMEM132C MYOF ROBO1 PCOLCE	6.12e-06	194	158	7	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYF5 VGLL2 F2R CHRNB1 PDP1 ADAMTS20 MEGF10	6.55e-06	196	158	7	3dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-MAIT\|ICU-SEP / Disease, condition lineage and cell class	NTN4 MFAP3 RND1 TMEM184A AASS JAG1 CAMKMT	7.23e-06	199	158	7	2f10622319c6146dfed8cfe3844180c1e1d56e94
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PAMR1 SH3BP2 LGR4 NBPF26 NBPF19 OAF NBPF10	7.47e-06	200	158	7	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PAMR1 SH3BP2 LGR4 NBPF26 NBPF19 OAF NBPF10	7.47e-06	200	158	7	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PAMR1 SH3BP2 LGR4 NBPF26 NBPF19 OAF NBPF10	7.47e-06	200	158	7	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PAMR1 SH3BP2 LGR4 NBPF26 NBPF19 OAF NBPF10	7.47e-06	200	158	7	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	PAMR1 SH3BP2 LGR4 NBPF26 NBPF19 OAF NBPF10	7.47e-06	200	158	7	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ECM2 ABHD6 F2R NOMO1 UNC5D NOMO3	1.80e-05	153	158	6	4eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ECM2 ABHD6 F2R NOMO1 UNC5D NOMO3	1.80e-05	153	158	6	26b5b45c117d155b028d298a0b93e16d343dca97
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ECM2 ABHD6 F2R NOMO1 UNC5D NOMO3	1.80e-05	153	158	6	0f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYF5 FAT3 MDGA2 CES4A UNC5D MEGF10	2.48e-05	162	158	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 EZH2 CHRNB1 MYOF FCGBP EPDR1	3.47e-05	172	158	6	c0bda7153e02bee7d0326138cc684151c404c2a1
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CUL2 PAMR1 ECM2 F2RL1 MFAP3 MDGA1	3.71e-05	174	158	6	eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCell	facs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CUL2 PAMR1 ECM2 F2RL1 MFAP3 MDGA1	3.71e-05	174	158	6	32fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NBPF26 EXT1 PLXND1 MPRIP RHOV ROBO1	3.83e-05	175	158	6	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NBPF26 EXT1 PLXND1 MPRIP RHOV ROBO1	3.83e-05	175	158	6	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	facs-Heart-RV-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 EZH2 RFX4 GPR174 NSG2 CCL5	3.95e-05	176	158	6	3e7647364c13beade9ca278c7ce8e89546e0b060
ToppCell	facs-Heart-RV-18m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SDK2 EZH2 RFX4 GPR174 NSG2 CCL5	3.95e-05	176	158	6	a55572470de6af6cbf29ed4f785fdca62d24cd23
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 ECM2 FAT3 TMEM132C PCOLCE	4.48e-05	180	158	6	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 ECM2 FAT3 TMEM132C PCOLCE	4.48e-05	180	158	6	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 ECM2 FAT3 TMEM132C OAF PCOLCE	4.62e-05	181	158	6	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	COVID-19_Convalescent\|World / Disease condition and Cell class	KLF6 NBPF26 NBPF20 NBPF19 NBPF15 NBPF14	4.62e-05	181	158	6	a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A FAT3 HIPK2 NTN4 JAG1 UNC5D	4.91e-05	183	158	6	738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A HIPK2 NTN4 JAG1 LRRN2 UNC5D	4.91e-05	183	158	6	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	droplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM53 FAT3 F2R GFRA2 TMEM132C PCOLCE	5.06e-05	184	158	6	89ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM53 FAT3 F2R GFRA2 TMEM132C PCOLCE	5.06e-05	184	158	6	4df6027fa635996c1eddb920f88a5265772df1cd
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PAMR1 MYO10 SH3BP2 RFX4 OAF MEGF10	5.37e-05	186	158	6	73cf266aeecd3cc15e8cb6094588a393bca8fbe6
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NBPF8 SH3BP2 RGS22 MDGA2 ADAMTS20 UNC5D	5.37e-05	186	158	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYF5 VGLL2 F2R CHRNB1 ADAMTS20 MEGF10	5.53e-05	187	158	6	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PSG4 DNER LGR4 PTAFR NTN4 MYOF	5.53e-05	187	158	6	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAMR1 FAT3 RGS22 TMEM132C MYOF EPDR1	5.70e-05	188	158	6	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ECM2 OAF LRRN2 EPDR1 MEGF10 PCOLCE	5.70e-05	188	158	6	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	Mesenchymal_cells-Osteoblasts\|World / Lineage and Cell class	LPAR3 SDK2 MYO10 FAT3 P3H1 PCOLCE	5.70e-05	188	158	6	89f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DLGAP1 MYO10 ECM2 FAT3 TMEM132C PKN2	5.87e-05	189	158	6	203c80030df08ae112f9ae4043709f455d87ce89
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PSG4 DNER LGR4 PTAFR NTN4 MYOF	5.87e-05	189	158	6	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PAMR1 FAT3 RGS22 DNER TMEM132C EPDR1	5.87e-05	189	158	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRK1 PLXND1 F2R EVA1C ARAP3 JAG1	6.04e-05	190	158	6	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	15-Distal-Mesenchymal-Mesenchyme_SERPINF1-high\|Distal / Age, Tissue, Lineage and Cell class	PAMR1 TFPI2 DNER PTAFR GFRA2 PCOLCE	6.04e-05	190	158	6	b47472dc9fe6ed99c2365203a3d8a59879e74a70
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|368C / Donor, Lineage, Cell class and subclass (all cells)	LGMN TMIGD3 PTAFR GFRA2 FCGBP PTPRJ	6.04e-05	190	158	6	cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 FAT3 TMEM132C ROBO1 PCOLCE	6.22e-05	191	158	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 FAT3 TMEM132C MYOF PCOLCE	6.40e-05	192	158	6	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 FAT3 TMEM132C MYOF ROBO1 PCOLCE	6.40e-05	192	158	6	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 FAT3 TMEM132C MYOF PCOLCE	6.40e-05	192	158	6	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	NS-critical-d_0-4-Lymphoid-NK\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	VWA8 SRM OAF ROBO1 CCL5 MEGF10	6.59e-05	193	158	6	1b29525c5936d1b779253b8c20f059fa091c6127
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KLF6 MYO9A LGR4 NTN4 MYOF PTPRJ	6.59e-05	193	158	6	f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCell	EC-Sinusoidal_ECs\|EC / Lineage and Cell class	LGMN TFPI2 PLXND1 F2R OAF BACE2	6.59e-05	193	158	6	1291b1d3494dcb4b9309f8bff63fb662e7eca0c8
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DLGAP1 MYO10 FAT3 TMEM132C AASS ROBO1	6.59e-05	193	158	6	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	DLGAP1 SDK2 MYO10 FAT3 F2R ROBO1	6.59e-05	193	158	6	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DLGAP1 SDK2 MYO10 FAT3 TMEM132C ROBO1	6.59e-05	193	158	6	acad568621ed677031797b8c2e34dafea798d681
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KLF6 MYO9A LGR4 NTN4 MYOF PTPRJ	6.59e-05	193	158	6	42df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KLF6 MYO9A LGR4 NTN4 MYOF PTPRJ	6.78e-05	194	158	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	HIPK2 EXT1 PLXND1 TMEM132C EVA1C ARAP3	6.78e-05	194	158	6	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 FAT3 TMEM132C ROBO1 PCOLCE	6.78e-05	194	158	6	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	LPAR3 SDK2 PAMR1 MYO10 FAT3 PCOLCE	6.78e-05	194	158	6	811b382ec3da06a6bda7360abc8b633f96b2019e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FAT3 SRM LGR4 TMEM132C OAF JAG1	6.78e-05	194	158	6	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 FAT3 TMEM132C MYOF ROBO1 PCOLCE	6.78e-05	194	158	6	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	LPAR3 SDK2 PAMR1 MYO10 FAT3 PCOLCE	6.78e-05	194	158	6	292ce9021678534c9eedb367b9772a9d976208a8
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	MYO9A EXT1 PTPRJ CAMKMT SPIDR SOS1	7.18e-05	196	158	6	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Mesenchymal_cells-Myofibroblasts\|World / Lineage and Cell class	MYF5 VGLL2 F2R CHRNB1 RND1 MEGF10	7.18e-05	196	158	6	2c0f429ae18c2df05c33ddf58dcc2c94b819b9a1
ToppCell	(2)_Fibroblasts-(22)_Fibro-3\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	LPAR3 FAT3 F2R GFRA2 LRRN2 BACE2	7.38e-05	197	158	6	d9021bab82403e566ec10f78acb227c0f80b88fe
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SRM FNDC3A ERLEC1 NOMO1 NOMO2 NOMO3	7.38e-05	197	158	6	99fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCell	COPD-Stromal-Fibroblast\|World / Disease state, Lineage and Cell class	PAMR1 TFPI2 ECM2 TMEM132C OAF PCOLCE	7.59e-05	198	158	6	2f13c0b3372af53d1bd85f9546f315c878580a71
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SDK2 PAMR1 ECM2 TMEM132C ROBO1 PCOLCE	7.59e-05	198	158	6	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	OR5AU1 EZH2 PRODH2 GPR174 CCL5 ZC3HAV1	7.59e-05	198	158	6	90863377ed36afc30bc1a068612ad1adc77af5a8
ToppCell	Parenchyma_Control_(B.)-Immune-TX-MoAM-3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	LGMN KLF6 OR10P1 TMIGD3 PTAFR GFRA2	7.80e-05	199	158	6	1ce46d9edabb3252f940a5143dd3f2404422d185
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	VWA8 EXT1 PTPRJ CAMKMT SPIDR SOS1	7.80e-05	199	158	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SDK2 MYO10 TMEM132C MYOF ROBO1 PCOLCE	7.80e-05	199	158	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	tumor_Lung-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	LGMN KLF6 TMIGD3 PLXND1 PTAFR SCARB2	8.02e-05	200	158	6	58ff8db0ecf71daa86f9a38208e0d9b712cac0b5
Drug	Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; HL60; HT_HG-U133A	INPP5K HIPK2 MTMR1 HIPK3 MYOF MFAP3 PLAA PDP1 SCARB2 PKN2	5.50e-07	190	150	10	2465_DN
Drug	Pesticides	NBPF8 NBPF12 NBPF11 NBPF20 NBPF1 NBPF15 NBPF9 NBPF10 NBPF14	6.92e-07	150	150	9	ctd:D010575
Drug	Benzbromarone [3562-84-3]; Up 200; 9.4uM; HL60; HT_HG-U133A	NEMP1 SH3BP2 FNDC3A PTAFR HIPK3 MFAP3 SLC25A40 SCARB2 CAMSAP2	4.69e-06	189	150	9	1291_UP
Disease	prostate cancer (is_marker_for)	EZH2 SETDB1 SETD5 EP300 DNMT1 SOS1	1.21e-04	156	144	6	DOID:10283 (is_marker_for)
Disease	colorectal adenoma	CUL2 FAT3 BACE2	5.58e-04	33	144	3	EFO_0005406
Disease	chemotherapy-induced alopecia, methylcobalamin deficiency type cblE	TMEM132C CAMKMT	6.50e-04	8	144	2	EFO_0005400, MONDO_0009354
Disease	ribose-5-phosphate measurement, ribulose-5-phosphate measurement	TMEM132C MEGF10	6.50e-04	8	144	2	EFO_0010529, EFO_0010530
Disease	insulin sensitivity measurement, glucose homeostasis measurement	LPAR3 SETD5 PKN2	1.22e-03	43	144	3	EFO_0004471, EFO_0006896
Disease	melanoma	TFPI2 VGLL2 F2RL1 SETDB1 ADAMTS20 EP300	1.41e-03	248	144	6	C0025202
Disease	pneumonia, COVID-19	RGS22 RFX4 MTNR1A UNC5D	2.32e-03	113	144	4	EFO_0003106, MONDO_0100096
Disease	IGFBP-3 measurement	DLGAP1 TSC2 MPRIP	2.35e-03	54	144	3	EFO_0004626
Disease	birth weight, parental genotype effect measurement	CNNM3 ARAP3 PTPRJ JAG1 DNMT1	2.57e-03	192	144	5	EFO_0004344, EFO_0005939
Disease	hypertrophic cardiomyopathy (is_marker_for)	KLHL41 DNMT1	3.07e-03	17	144	2	DOID:11984 (is_marker_for)
Disease	oral motor function measurement	LGMN DLGAP1	3.07e-03	17	144	2	EFO_0021793
Disease	response to opioid	DLGAP1 TMEM132C SEC23IP	3.33e-03	61	144	3	EFO_0008541
Disease	cD177 antigen measurement	PSG4 PSG6	3.44e-03	18	144	2	EFO_0021866
Disease	Inflammation	TSC2 F2R F2RL1 PLAA	3.54e-03	127	144	4	C0021368
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A CHRNB1	3.83e-03	19	144	2	C0751884
Disease	obstructive sleep apnea	GAPVD1 ECM2 CAMKMT	4.16e-03	66	144	3	EFO_0003918

Protein segments in the cluster

Peptide	Gene	Start	Entry
VYAAYYPSDVSSLCL	ABHD6	156	Q9BV23
PLFKQSSCSYRIESY	ERLEC1	106	Q96DZ1
QLCTIPRDATYYSYQ	EP300	1181	Q09472
DCYPVQETFTINYSV	EPDR1	171	Q9UM22
VIYCDQYASLIPVSF	BEST2	66	Q8NFU1
YECYRFGISPSTNAL	BACE2	391	Q9Y5Z0
RATYSGFLYCSPVSN	ARAP3	676	Q8WWN8
SLVVSFLSYCDYYRP	DNMT1	1246	P26358
RLYSLQSDPATYCNE	BSDC1	121	Q9NW68
YISRFNTDIAPYTTC	AASS	291	Q9UDR5
RCVYYFKSSTSASPQ	SH3BP2	56	P78314
IYRSSCSIQVTYFPF	CHRNB1	146	P11230
RCPDRSASQYFLEAY	DLGAP1	226	O14490
FSYRQRITYCTEIPS	ADAMTS20	1606	P59510
QPDYEATSQSYSRCL	PRODH2	401	Q9UF12
INSNYEFCDTYPAII	MTMR1	251	Q13613
VYLCYTVSREDGSFS	NOMO3	266	P69849
TYCRYDSVSVFNGAV	PCOLCE	211	Q15113
ANTCYTSPSVHSARY	RFX4	681	Q33E94
CTDYIPRSSNDYTSQ	EYA3	56	Q99504
DTPLYFSYSHLVCRT	P3H1	556	Q32P28
TAYDRYVAICSPLLY	OR8G2P	131	Q6IF36
PQDYASYTCQVSVRN	MDGA1	206	Q8NFP4
PFDQIYYTSCTDILN	MEGF10	51	Q96KG7
AYDRFVAICNPLQYT	OR52E4	121	Q8NGH9
VYLCYTVSREDGSFS	NOMO2	266	Q5JPE7
QNFDDASPTYSYCLL	PTPRJ	646	Q12913
ANAYSRSVCAYDPAS	KLHL31	476	Q9H511
TFDSIYCPDVSNVYA	MYF5	181	P13349
SACYDVTEYPVQRNY	MPRIP	436	Q6WCQ1
AVCSTYLQSRYYRAP	HIPK2	356	Q9H2X6
STTYQLCARYFCGVP	LRRK1	1766	Q38SD2
FPLFTAVYQICYESR	GPD1L	321	Q8N335
YTPRSSYREATTVDC	LRRN2	41	O75325
PCLLSTVQYISSFYA	GAPVD1	1436	Q14C86
TYYDNFCAIARLIGT	EZH2	446	Q15910
NFTIYDCSRTAQVYP	PLXND1	696	Q9Y4D7
CGDLLSRSQIFYYST	NEMP1	176	O14524
RFSEDCLYLNVYAPA	CES4A	111	Q5XG92
RCIPASLDAYYSSQD	NSG2	111	Q9Y328
CASCLVPTVAQYRFY	FUT7	211	Q11130
VYLCYTVSREDGSFS	NOMO1	266	Q15155
RDSVYSCVTLPYFHS	MYO10	1166	Q9HD67
LSACSPYFREYFLSE	KLHL41	51	O60662
CSSLAPIYSRSYLVF	LPAR3	176	Q9UBY5
FVNLRSLSVPYAYQC	LGR4	456	Q9BXB1
ASLNSCLDPVIYYFS	GPR174	281	Q9BXC1
SSCVFQERNYPRTYV	HIPK3	31	Q9H422
CSTYLQSRYYRAPEI	HIPK3	356	Q9H422
LNSVTPEDTAVYYCA	IGHV6-1	106	A0A0B4J1U7
TDSCQPYRSAFYILE	NBPF1	921	Q3BBV0
YDRYAAICNPLLYSS	OR5AN1	121	Q8NGI8
CSQAVSERLFYYIAV	PDP1	151	Q9P0J1
LRPQDYANYSCIASV	MDGA2	206	Q7Z553
LYTCFVTSPIRASYS	MFAP3	121	P55082
SAAAVICAYLVEYSP	PPP4R3C	381	Q6ZMV5
IDPLIYYYASSECQR	F2R	366	P25116
YDRFVAICSPLLYST	OR5P2	116	Q8WZ92
RAPFSISAFSYICEN	PARP11	106	Q9NR21
CLSTLNSCIDPFVYY	F2RL1	331	P55085
SGFCRTSYPIYSSIE	EVA1C	391	P58658
NVSYICSRYYRAPEL	GSK3A	276	P49840
SVYLDTTFCDPRFYQ	DCLRE1C	161	Q96SD1
SRFYTSDPSQACLFV	EXT1	141	Q16394
RASYQTVTSCPADNY	GFRA2	276	O00451
ALQAAEYFYPSTDCV	COLCA2	116	A8K830
VLSPSEYFRQCVYDL	FCGBP	5066	Q9Y6R7
PATTYYCRVQALSVV	FNDC3A	821	Q9Y2H6
SNIPTTEDEFLLCYY	INPP5K	401	Q9BT40
TYSTARISFVCPRFY	FAT3	3766	Q8TDW7
NDRFSDIYALCVAYP	CUL2	36	Q13617
VSIFRYCAPTAYTAS	C19orf67	211	A6NJJ6
YSSDTTPCCFAYIAR	CCL5	26	P13501
EIPSYTFSCIRSYSS	ECM2	676	O94769
YQYLAADCTSTFPRV	LAMB3	146	Q13751
TISSLQPEDVATYYC	IGKV1-27	96	A0A075B6S5
ISSLQPEDFAVYYCQ	IGKV3-7	96	A0A075B6H7
LNFVSRTCYPLSYFS	KRTAP25-1	36	Q3LHN0
GSSRPAYEEFYNCRS	DNER	671	Q8NFT8
YLSCFAESNPRAQYS	PSG4	351	Q00888
NITATFQYLYLCPSE	SCAF4	91	O95104
YYECEAVLRSSSVPS	SDK2	281	Q58EX2
DSPGYDFSCLVQRVY	SCAP	906	Q12770
GCQFRSLYTYCPETE	CAMSAP2	1406	Q08AD1
RSFTSNDECPSEYYH	DEFB131B	21	A0A096LNP1
ENTYYREICSAPSGR	MAP3K19	681	Q56UN5
YSDPYISQRLCFIIA	OR5D13	191	Q8NGL4
QYECISPFYRRLGSS	PAMR1	411	Q6UXH9
LLSAVPISYLCTYYA	PANX2	236	Q96RD6
EEYTFSLPCAYARSI	OSBPL11	561	Q9BXB4
NVSAEYSIYIACEPS	JAG1	991	P78504
SSPYTCSRAVSLFFV	OTOG	201	Q6ZRI0
RYSHDLSDSPYSVVC	MKRN1	76	Q9UHC7
LSDSPYSVVCKYFQR	MKRN1	81	Q9UHC7
YDRYVAICQPLRYST	OR10P1	121	Q8NGE3
PEAAQQTYSLVCDAY	PARS2	216	Q7L3T8
SINSCYPEEIVRYYS	SPAG6	476	O75602
VNFTYQYLSAPLCVT	TMEM132C	506	Q8N3T6
PATVIYFTCYDQLSA	SLC25A40	116	Q8TBP6
IITYCSPLYFANSEI	SLC26A9	531	Q7LBE3
YCFYSENTDLTCRQP	NTN4	61	Q9HB63
DSCQPYRSAFYILEQ	NBPF8	616	Q3BBV2
DSCQPYRSAFYVLEQ	NBPF9	651	P0DPF3
DSCQPYRSAFYILEQ	NBPF10	651	Q6P3W6
LELTDSCQPYRSAFY	NBPF10	891	Q6P3W6
ELTDSCQPYRSAFYV	NBPF10	1136	Q6P3W6
LTDSCQPYRSAFYVL	NBPF10	1381	Q6P3W6
TDSCQPYRSAFYVLE	NBPF10	1626	Q6P3W6
DSCQPYRSAFYVLEQ	NBPF10	1871	Q6P3W6
LELTDSCQPYRSAFY	NBPF10	2111	Q6P3W6
ELTDSCQPYRSAFYV	NBPF10	2356	Q6P3W6
LTDSCQPYRSAFYVL	NBPF10	2601	Q6P3W6
TDSCQPYRSAFYVLE	NBPF10	2846	Q6P3W6
DSCQPYRSAFYVLEQ	NBPF10	3091	Q6P3W6
LELTDSCQPYRSAFY	NBPF10	3331	Q6P3W6
ELCDSCQPYRSAFYV	NBPF10	3576	Q6P3W6
DSCQPYRSAFYVLEQ	NBPF11	651	Q86T75
TDSCQPYRSAFYVLE	NBPF12	921	Q5TAG4
DSCQPYRSAFYVLEQ	NBPF14	311	Q5TI25
LELTDSCQPYRSAFY	NBPF14	551	Q5TI25
LELTDSCQPYRSAFY	NBPF14	626	Q5TI25
LELTDSCQPYRSAFY	NBPF15	376	Q8N660
LELTDSCQPYRSAFY	NBPF19	376	A0A087WUL8
ELTDSCQPYRSAFYI	NBPF19	621	A0A087WUL8
LTDSCQPYRSAFYIL	NBPF19	866	A0A087WUL8
TDSCQPYRSAFYILE	NBPF19	1111	A0A087WUL8
DSCQPYRSAFYILEQ	NBPF19	1356	A0A087WUL8
LELTDSCQPYRSAFY	NBPF19	1596	A0A087WUL8
ELTDSCQPYRSAFYI	NBPF19	1841	A0A087WUL8
LTDSCQPYRSAFYIL	NBPF19	2086	A0A087WUL8
TDSCQPYRSAFYILE	NBPF19	2331	A0A087WUL8
DSCQPYRSAFYILEQ	NBPF19	2576	A0A087WUL8
LELTDSCQPYRSAFY	NBPF19	2816	A0A087WUL8
ELTDSCQPYRSAFYI	NBPF19	3061	A0A087WUL8
LTDSCQPYRSAFYIL	NBPF19	3306	A0A087WUL8
TDSCQPYRSAFYILE	NBPF19	3551	A0A087WUL8
DSCQPYRSAFYVLEQ	NBPF20	36	P0DPF2
LELTDSCQPYRSAFY	NBPF20	276	P0DPF2
ELTDSCQPYRSAFYV	NBPF20	521	P0DPF2
LTDSCQPYRSAFYVL	NBPF20	766	P0DPF2
TDSCQPYRSAFYVLE	NBPF20	1011	P0DPF2
DSCQPYRSAFYVLEQ	NBPF20	1256	P0DPF2
LELTDSCQPYRSAFY	NBPF20	1496	P0DPF2
ELTDSCQPYRSAFYV	NBPF20	1741	P0DPF2
LTDSCQPYRSAFYVL	NBPF20	1986	P0DPF2
TDSCQPYRSAFYVLE	NBPF20	2231	P0DPF2
DSCQPYRSAFYVLEQ	NBPF20	2476	P0DPF2
LELTDSCQPYRSAFY	NBPF20	2716	P0DPF2
ELTDSCQPYRSAFYV	NBPF20	2961	P0DPF2
LTDSCQPYRSAFYVL	NBPF20	3206	P0DPF2
TDSCQPYRSAFYVLE	NBPF20	3451	P0DPF2
DSCQPYRSAFYVLEQ	NBPF20	3696	P0DPF2
LELTDSCQPYRSAFY	NBPF20	3936	P0DPF2
ELTDSCQPYRSAFYV	NBPF20	4181	P0DPF2
TDSCQPYRSAFYVLE	NBPF20	4671	P0DPF2
DSCQPYRSAFYVLEQ	NBPF20	4916	P0DPF2
DSCQPYRSAFYVLEQ	NBPF26	311	B4DH59
DSCQPYRSAFYILEQ	NBPF26	386	B4DH59
DSCQPYRSAFYILEQ	NBPF26	461	B4DH59
DSCQPYRSAFYILEQ	NBPF26	536	B4DH59
DSCQPYRSAFYILEQ	NBPF26	611	B4DH59
AQYLFATYVAPSATL	RGS22	721	Q8NE09
VLAFTCEPKSRNYTY	PSG6	256	Q00889
PFRSFANTLVDVCAY	PSMD2	586	Q13200
TYCSVAFLGVITYNR	PTAFR	101	P25105
TYVPTVFENYTACLE	RND1	41	Q92730
ASVALRYAFPCQVYA	TMEM184A	316	Q6ZMB5
YDRYAAICNPLLYST	OR5AU1	171	Q8NGC0
CADAYLTPAIQRYVQ	OPLAH	236	O14841
ATCAFQRDYYVSTAV	SPP2	101	Q13103
VYSPSRYSYQLLQCD	SETD5	1231	Q9C0A6
VAPSRAIYFAAYSNC	SLC25A36	91	Q96CQ1
LYVFPSDFCRSVYIT	SCARB2	266	Q14108
TDCNLSPTLRYAFYL	NLRP7	196	Q8WX94
LLDILFYNSPTYCQT	SEC23IP	536	Q9Y6Y8
TDVFSEPRAVFYAAC	PKN2	751	Q16513
FSVVSYLLNPSYLDC	PPP1R15B	216	Q5SWA1
PNFVRTFLTTYRSFC	SOS1	621	Q07889
SYSFDFYVPQRQLCL	OAF	251	Q86UD1
VAPSRAVYFACYSKA	SLC25A33	101	Q9BSK2
YASYVTQSELYPICR	SETDB1	301	Q15047
YTSIFCPEYSISLRH	CAMKMT	91	Q7Z624
SSAYCPDYTVRALSD	CNNM3	621	Q8NE01
FYRYNIVLGSQCISS	TRIM68	341	Q6AZZ1
PYLYDFLDAVITCQT	TTC30B	356	Q8N4P2
SLIVSYTCNGYPARY	RHOV	46	Q96L33
PEAEYINSRCVLFTY	VGLL2	76	Q8N8G2
VAVCYGSFYNLLTRT	PIGT	536	Q969N2
NDLGTRCSFYATVIY	SPIDR	641	Q14159
LRDYPTYYTSLCVDF	TMEM53	256	Q6P2H8
TNYIYSISVFPNCRD	PLAA	231	Q9Y263
FLCDVVYSPYATLAS	UGT1A1	221	P22309
LTTYSRPADCIANYN	ROBO1	1006	Q9Y6N7
RQFCQSLFPVVAYAY	SRM	221	P19623
CDVRAYFTTPIFYVN	MARS2	41	Q96GW9
YNLRVYCVDNTPCAF	UNC5D	706	Q6UXZ4
FYATSRAYVESICSN	ZC3HAV1	786	Q7Z2W4
FNPRYRTCDAFTYTG	TFPI2	176	P48307
SNFYSDTYACPVCRE	ZNF142	246	P52746
LQCSVYSALYPAVSR	VPS9D1	291	Q9Y2B5
FRDYCNIIAFSPNST	TMIGD3	111	P0DMS9
NTLYVVTCNPASLYF	VWA8	1126	A3KMH1
YRSCGFSYEQDPTLR	PRSS50	101	Q9UI38
SLPRVSLSDTAVYYC	TRAV4	91	A0A0B4J268
FYYEQAPSASLCIAI	ZFYVE26	1926	Q68DK2
AYSRLYQSLEFPSSC	UNC13D	356	Q70J99
AAEQYASVFAISLPY	TSC2	861	P49815
RYLQSEPCYVSASEI	KLF6	41	Q99612
GTLQYDPRIYSCTFA	MTNR1A	166	P48039
ATTAANPRESSYACY	LGMN	206	Q99538
QYSIPTYCEYCSSLI	MYO9A	2006	B2RTY4
TPIVSCNFDRVYIYH	MYOF	1126	Q9NZM1