Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modification-dependent protein binding	MSH6 ANK2 SMARCA4 KMT2A KMT2E PHIP TP53BP1	4.37e-05	206	91	7	GO:0140030
GeneOntologyMolecularFunction	histone binding	MSH6 SMARCA4 KMT2A SMARCC2 KMT2E PHIP TP53BP1	2.10e-04	265	91	7	GO:0042393
GeneOntologyMolecularFunction	lysine-acetylated histone binding	SMARCA4 KMT2A PHIP	3.40e-04	30	91	3	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	SMARCA4 KMT2A PHIP	3.75e-04	31	91	3	GO:0140033
GeneOntologyMolecularFunction	molecular adaptor activity	TPR LPIN1 ANK2 GAS2L2 SYNE2 TNRC6A SMARCA4 SMARCC2 ATG14 TACC1 EIF3B KMT2E PCM1 AKAP12 TP53BP1 MAPK8IP3	3.83e-04	1356	91	16	GO:0060090
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	TPR LPIN1 ANK2 GAS2L2 SYNE2 TNRC6A SMARCA4 SMARCC2 ATG14 TACC1 KMT2E AKAP12 TP53BP1 MAPK8IP3	7.41e-04	1160	91	14	GO:0030674
GeneOntologyMolecularFunction	DNA secondary structure binding	MSH6 KMT2A YY1	8.61e-04	41	91	3	GO:0000217
GeneOntologyMolecularFunction	retromer complex binding	WASHC2C WASHC2A	9.03e-04	10	91	2	GO:1905394
GeneOntologyMolecularFunction	protein-membrane adaptor activity	TPR SYNE2 ATG14	1.13e-03	45	91	3	GO:0043495
GeneOntologyCellularComponent	costamere	ANK2 AHNAK AHNAK2	1.20e-04	22	92	3	GO:0043034
GeneOntologyCellularComponent	kinetochore	TPR CENPT KANSL1 SMARCA4 SMARCC2 TP53BP1	1.49e-04	181	92	6	GO:0000776
GeneOntologyCellularComponent	condensed chromosome, centromeric region	TPR CENPT KANSL1 SMARCA4 SMARCC2 TP53BP1	2.12e-04	193	92	6	GO:0000779
GeneOntologyCellularComponent	Z disc	MYH6 IGFN1 ANK2 SYNE2 AHNAK2	5.46e-04	151	92	5	GO:0030018
GeneOntologyCellularComponent	I band	MYH6 IGFN1 ANK2 SYNE2 AHNAK2	8.38e-04	166	92	5	GO:0031674
GeneOntologyCellularComponent	bBAF complex	SMARCA4 SMARCC2	8.43e-04	10	92	2	GO:0140092
GeneOntologyCellularComponent	myofibril	MYH6 IGFN1 ANK2 AHNAK SYNE2 AHNAK2	1.31e-03	273	92	6	GO:0030016
GeneOntologyCellularComponent	chromosome, centromeric region	TPR CENPT KANSL1 SMARCA4 SMARCC2 TP53BP1	1.39e-03	276	92	6	GO:0000775
GeneOntologyCellularComponent	npBAF complex	SMARCA4 SMARCC2	1.68e-03	14	92	2	GO:0071564
GeneOntologyCellularComponent	ciliary basal body	DNAAF2 GAS2L2 SSX2IP CFAP410 PCM1	1.71e-03	195	92	5	GO:0036064
GeneOntologyCellularComponent	contractile muscle fiber	MYH6 IGFN1 ANK2 AHNAK SYNE2 AHNAK2	1.78e-03	290	92	6	GO:0043292
GeneOntologyCellularComponent	WASH complex	WASHC2C WASHC2A	1.94e-03	15	92	2	GO:0071203
GeneOntologyCellularComponent	RSC-type complex	SMARCA4 SMARCC2	1.94e-03	15	92	2	GO:0016586
GeneOntologyCellularComponent	nBAF complex	SMARCA4 SMARCC2	2.21e-03	16	92	2	GO:0071565
GeneOntologyCellularComponent	condensed chromosome	TPR CENPT KANSL1 SMARCA4 SMARCC2 TP53BP1	2.37e-03	307	92	6	GO:0000793
MousePheno	abnormal hormone-sensitive lipase activity	LPIN1 MAF1	2.84e-05	2	75	2	MP:0011589
Domain	FAM21	WASHC2C WASHC2A	2.40e-05	2	92	2	IPR027308
Domain	FAM21/CAPZIP	WASHC2C WASHC2A	7.18e-05	3	92	2	IPR029341
Domain	CAP-ZIP_m	WASHC2C WASHC2A	7.18e-05	3	92	2	PF15255
Domain	BROMODOMAIN_2	SMARCA4 KMT2A PHIP	1.08e-03	41	92	3	PS50014
Domain	BROMO	SMARCA4 KMT2A PHIP	1.16e-03	42	92	3	SM00297
Domain	Bromodomain	SMARCA4 KMT2A PHIP	1.16e-03	42	92	3	IPR001487
Domain	-	SMARCA4 KMT2A PHIP	1.16e-03	42	92	3	1.20.920.10
Domain	Ig_I-set	NEO1 IGFN1 HMCN2 ALPK3 CNTN6	2.49e-03	190	92	5	IPR013098
Domain	I-set	NEO1 IGFN1 HMCN2 ALPK3 CNTN6	2.49e-03	190	92	5	PF07679
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KANSL1 KMT2A BOD1L1 KAT14	3.62e-05	38	70	4	MM17073
Pathway	REACTOME_FORMATION_OF_WDR5_CONTAINING_HISTONE_MODIFYING_COMPLEXES	KANSL1 KMT2A BOD1L1 KAT14	5.41e-05	42	70	4	M48018
Pubmed	Human transcription factor protein interaction networks.	SALL2 ATXN7L2 KANSL1 ZKSCAN1 SYNE2 TNRC6A GNL2 SMARCA4 CPSF1 KMT2A SMARCC2 SMG5 PPP6R1 EIF3B WASHC2A YY1 KAT14 DCAF5 PCM1 TP53BP1 SP7 FTSJ3	2.00e-11	1429	93	22	35140242
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MSH6 ZNF469 SALL2 ATXN7L2 DCAF8 HMCN2 SSX2IP TNRC6A GNL2 SMARCA4 SMARCC2 PPP6R1 ADGRL2 YY1 KAT14 PHIP DCAF5 PCM1 FTSJ3	1.09e-10	1116	93	19	31753913
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TPR MSH6 AHNAK SYNE2 INTS1 GNL2 SMARCA4 CPSF1 KMT2A SMARCC2 BOP1 PHIP PCM1 TP53BP1 FTSJ3	2.19e-10	653	93	15	22586326
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TPR MSH6 TBC1D4 KANSL1 WASHC2C HIRIP3 SMARCA4 CPSF1 KMT2A SMARCC2 EIF3B YY1 PCM1 TP53BP1 MAPK8IP3	2.22e-09	774	93	15	15302935
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	TPR MSH6 ANK2 AHNAK INTS1 GNL2 SMARCA4 SMARCC2 TP53BP1 FTSJ3	3.20e-09	271	93	10	32433965
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TPR MSH6 WASHC2C ANK2 AHNAK GNL2 SMARCA4 KMT2A BOD1L1 TACC1 PPP6R1 PCM1 AKAP12 TP53BP1 AHNAK2 FTSJ3	3.56e-09	934	93	16	33916271
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	COL18A1 NEO1 KIDINS220 DCAF8 ANK2 SYNE2 SSX2IP GNL2 BOP1 TACC1 PPP6R1 ADGRL2 WASHC2A DCAF5 PCM1 AKAP12 TP53BP1 FTSJ3	7.10e-08	1487	93	18	33957083
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	TPR MSH6 COL18A1 AHNAK SMARCA4 CPSF1 SMARCC2 TP53BP1	7.81e-08	203	93	8	22083510
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	MSH6 CENPT HIRIP3 INTS1 GNL2 SMARCA4 KMT2A SMARCC2 BOP1 BOD1L1 YY1 PHIP	8.41e-08	608	93	12	36089195
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	MSH6 CENPT SSX2IP KMT2A BOP1 YY1 PCM1 FTSJ3	1.01e-07	210	93	8	16565220
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PHLDB3 TPR RIN1 MSH6 TBC1D4 KANSL1 PLEKHG4 AHNAK SMARCA4 CPSF1 SMARCC2 BOP1 EIF3B PHIP TP53BP1 AHNAK2 FTSJ3	1.02e-07	1353	93	17	29467282
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	DCAF8 KANSL1 WASHC2C BOP1 SMG5 WASHC2A PHIP PCM1 CFB TP53BP1	6.04e-07	475	93	10	31040226
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	TPR RIN1 MSH6 TBC1D4 WASHC2C HIRIP3 BOP1 PCM1 TP53BP1 FTSJ3	1.01e-06	503	93	10	16964243
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	TPR MSH6 SMARCA4 CPSF1 SMARCC2 BOD1L1 EIF3B WASHC2A KAT14 TP53BP1	1.07e-06	506	93	10	30890647
Pubmed	EVI1 oncoprotein interacts with a large and complex network of proteins and integrates signals through protein phosphorylation.	TPR MSH6 SMARCA4 SMARCC2 YY1 TP53BP1	1.30e-06	128	93	6	23858473
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIDINS220 KANSL1 WASHC2C BOD1L1 PPP6R1 WASHC2A DCAF5 STRIP2 RUSC2	1.52e-06	407	93	9	12693553
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	TBC1D4 KIDINS220 SSX2IP TNRC6A PPP6R1 WASHC2A PCM1	1.57e-06	209	93	7	36779422
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	TPR CENPT AHNAK GNL2 SMARCA4 KMT2A SMARCC2 BOD1L1 YY1 PHIP PCM1 TP53BP1 FTSJ3	1.57e-06	954	93	13	36373674
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPR ANK2 ZKSCAN1 SYNE2 FBXO41 SMARCA4 SMARCC2 PPP6R1 ARMCX4 PCM1 AKAP12 TP53BP1 MAPK8IP3	1.74e-06	963	93	13	28671696
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	TPR NEO1 WASHC2C ANK2 TNRC6A FBXO41 SMARCC2 TACC1 PPP6R1 EIF3B WASHC2A PCM1 TP53BP1 MAPK8IP3	2.01e-06	1139	93	14	36417873
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TPR SALL2 TBC1D4 KANSL1 PLEKHG4 SMARCA4 SMARCC2 SMG5 PPP6R1 ADGRL2 YY1 TP53BP1	3.11e-06	857	93	12	25609649
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	AHNAK SMARCA4 TACC1 EIF3B ADGRL2 CLSTN1 PCM1 AHNAK2	3.19e-06	332	93	8	37433992
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	TPR MSH6 WASHC2C AHNAK SMARCA4 BOD1L1 TP53BP1 AHNAK2	3.19e-06	332	93	8	32786267
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	TPR AHNAK SYNE2 INTS1 GNL2 SMARCA4 CPSF1 SMARCC2 BOP1 EIF3B PHIP PCM1 FTSJ3	3.41e-06	1024	93	13	24711643
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	MSH6 SMARCA4 CPSF1 EIF3B AKAP12 TP53BP1	3.65e-06	153	93	6	26365490
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LPIN1 SALL2 SYNE2 MAPK8IP3 TECPR1	3.81e-06	87	93	5	12465718
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PHLDB3 NEO1 TNRC6A GNL2 SMARCA4 BOD1L1 TACC1 WASHC2A YY1 PCM1 STRIP2	4.30e-06	733	93	11	34672954
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	AHNAK INTS1 TNRC6A SMARCA4 KMT2A SMARCC2 BOD1L1 PHIP TP53BP1	4.83e-06	469	93	9	27634302
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	TPR MSH6 ZKSCAN1 GNL2 SMARCA4 KMT2A SMARCC2 BOP1 EIF3B FTSJ3	5.22e-06	605	93	10	28977666
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	HIRIP3 AHNAK SMARCA4 CPSF1 KMT2A BOD1L1 TP53BP1	5.24e-06	251	93	7	31076518
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	WASHC2C SYNE2 SSX2IP BOP1 EIF3B WASHC2A PCM1	5.24e-06	251	93	7	29778605
Pubmed	Msd1/SSX2IP-dependent microtubule anchorage ensures spindle orientation and primary cilia formation.	SSX2IP PCM1	7.07e-06	2	93	2	24397932
Pubmed	AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation.	AHNAK TP53BP1	7.07e-06	2	93	2	33961796
Pubmed	Identification of a novel Rev-interacting cellular protein.	WASHC2C WASHC2A	7.07e-06	2	93	2	15847701
Pubmed	Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).	WASHC2C WASHC2A	7.07e-06	2	93	2	20827171
Pubmed	The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.	AHNAK AHNAK2	7.07e-06	2	93	2	15007166
Pubmed	AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.	AHNAK AHNAK2	7.07e-06	2	93	2	20833135
Pubmed	FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.	WASHC2C WASHC2A	7.07e-06	2	93	2	36717248
Pubmed	Tetrandrine Inhibits the Intracellular Calcium Ion Level and Upregulates the Expression of Brg1 and AHNAK in Hep-2 Cells.	AHNAK SMARCA4	7.07e-06	2	93	2	26642721
Pubmed	Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.	ANK2 AHNAK CNTN6	1.01e-05	16	93	3	21745462
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	MSH6 COL18A1 AHNAK IFRD2 INTS1 TNRC6A GNL2 SMARCA4 KMT2A BOP1 EIF3B YY1 PHIP FTSJ3	1.07e-05	1318	93	14	30463901
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	HIRIP3 AHNAK INTS1 KMT2A SMARCC2 BOP1 TP53BP1 FTSJ3	1.11e-05	394	93	8	27248496
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	TPR MSH6 GNL2 SMARCA4 BOD1L1 YY1 ACAP3	1.14e-05	283	93	7	30585729
Pubmed	Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.	MSH6 SMARCA4 CPSF1 SMARCC2 YY1	1.56e-05	116	93	5	21549307
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	TPR WASHC2C GNL2 SMARCA4 CPSF1 KMT2A SMARCC2 BOP1 EIF3B YY1 FTSJ3	1.66e-05	847	93	11	35850772
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	TPR MSH6 AHNAK INTS1 SMARCA4 CPSF1 KMT2A SMARCC2 BOP1 BOD1L1 EIF3B YY1	1.68e-05	1014	93	12	32416067
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TPR SALL2 TBC1D4 AHNAK TNRC6A PPP6R1 KAT14 PCM1	1.70e-05	418	93	8	34709266
Pubmed	The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone.	SSX2IP PCM1	2.12e-05	3	93	2	24356449
Pubmed	Self-regulated alternative splicing at the AHNAK locus.	AHNAK AHNAK2	2.12e-05	3	93	2	21940993
Pubmed	Preameloblast-Derived Factors Mediate Osteoblast Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Runx2-Osterix-BSP Signaling.	IBSP SP7	2.12e-05	3	93	2	26413977
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	GNL2 CPSF1 PPP6R1 PCM1 FTSJ3	2.23e-05	125	93	5	29467281
Pubmed	Structural basis for activity regulation of MLL family methyltransferases.	KMT2A BOD1L1 KMT2E	2.75e-05	22	93	3	26886794
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	SALL2 TBC1D4 WASHC2C TNRC6A PPP6R1 WASHC2A KAT14 PCM1 TP53BP1	2.90e-05	588	93	9	38580884
Pubmed	BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.	SSX2IP TNRC6A BOP1 SMG5 WASHC2A PCM1	3.35e-05	226	93	6	25900982
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	TPR FAT2 AHNAK SMARCA4 SMARCC2 YY1	4.07e-05	234	93	6	36243803
Pubmed	AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.	AHNAK AHNAK2	4.23e-05	4	93	2	17185750
Pubmed	Constitutive expression of the brg1 gene requires GC-boxes near to the transcriptional start site.	SMARCA4 YY1	4.23e-05	4	93	2	21149256
Pubmed	Activity-dependent neuroprotective protein constitutes a novel element in the SWI/SNF chromatin remodeling complex.	SMARCA4 SMARCC2	4.23e-05	4	93	2	17878164
Pubmed	The tumor suppressor hSNF5/INI1 modulates cell growth and actin cytoskeleton organization.	SMARCA4 SMARCC2	4.23e-05	4	93	2	15150092
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	AHNAK SSX2IP INTS1 TNRC6A PPP6R1 WASHC2A	4.91e-05	242	93	6	34011540
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	MSH6 KANSL1 SMARCA4 SMARCC2 TP53BP1	5.34e-05	150	93	5	28242625
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	COL18A1 TBC1D4 DCAF8 ZKSCAN1 SSX2IP TNRC6A KMT2A PCM1 AKAP12	5.50e-05	639	93	9	23443559
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	TPR AHNAK TNRC6A SMARCA4 SMARCC2 EIF3B AKAP12 TP53BP1	5.55e-05	494	93	8	26831064
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	INTS1 ALPK3 BOD1L1 TECPR1 DNAH1	5.87e-05	153	93	5	10718198
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	TPR SMARCA4 SMARCC2 EIF3B TP53BP1 FTSJ3	5.87e-05	250	93	6	33536335
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	TPR DCAF8 KANSL1 WASHC2C AHNAK SMARCA4 SMARCC2 EIF3B WASHC2A PCM1 AKAP12 TP53BP1	5.95e-05	1155	93	12	20360068
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	MSH6 GNL2 SMARCA4 SMARCC2 BOP1 YY1 FTSJ3	6.30e-05	370	93	7	22922362
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	NEO1 KIDINS220 WASHC2C SYNE2 TACC1 ADGRL2 WASHC2A AKAP12	6.38e-05	504	93	8	34432599
Pubmed	Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.	PHIP CFAP410 STRIP2	6.43e-05	29	93	3	21834987
Pubmed	Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes.	SMARCA4 SMARCC2	7.04e-05	5	93	2	12244326
Pubmed	The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.	SMARCA4 SMARCC2	7.04e-05	5	93	2	18086889
Pubmed	A small modulatory dsRNA specifies the fate of adult neural stem cells.	SMARCA4 SMARCC2	7.04e-05	5	93	2	15035981
Pubmed	p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.	SMARCA4 SMARCC2	7.04e-05	5	93	2	9584200
Pubmed	Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2.	RIN1 HIRIP3 SMARCA4 SMG5 PPP6R1	7.47e-05	161	93	5	32572027
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	TPR AHNAK KMT2A PHIP	8.60e-05	86	93	4	37253089
Pubmed	Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.	DCAF8 PHIP DCAF5	8.68e-05	32	93	3	16964240
Pubmed	Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.	SSX2IP TNRC6A EIF3B ADGRL2 PCM1	9.40e-05	169	93	5	31462741
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	MSH6 CENPT SMARCA4 KMT2A SMARCC2 BOP1 PHIP FTSJ3	9.40e-05	533	93	8	30554943
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TPR MSH6 TBC1D4 AHNAK SYNE2 GNL2 SMARCA4 SMARCC2 PPP6R1 EIF3B YY1 AHNAK2 FTSJ3	9.97e-05	1415	93	13	28515276
Pubmed	USP53 plays an antitumor role in hepatocellular carcinoma through deubiquitination of cytochrome c.	MSH6 TNRC6A GNL2 FTSJ3	1.03e-04	90	93	4	35654790
Pubmed	Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.	SMARCA4 SMARCC2	1.05e-04	6	93	2	16940996
Pubmed	Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.	MYH6 SMARCA4	1.05e-04	6	93	2	26952936
Pubmed	Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression.	SMARCA4 SMARCC2	1.05e-04	6	93	2	21095589
Pubmed	Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling.	IBSP SP7	1.05e-04	6	93	2	33824347
Pubmed	Cell fate specification during calvarial bone and suture development.	IBSP SP7	1.05e-04	6	93	2	17931618
Pubmed	The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.	SMARCA4 SMARCC2	1.05e-04	6	93	2	16230384
Pubmed	BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.	SMARCA4 SMARCC2	1.05e-04	6	93	2	10943845
Pubmed	Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.	ABCA1 SMARCA4	1.05e-04	6	93	2	15774904
Pubmed	mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts.	IBSP SP7	1.05e-04	6	93	2	26090674
Pubmed	ClC-3 chloride channel mediates the role of parathyroid hormone [1-34] on osteogenic differentiation of osteoblasts.	IBSP SP7	1.05e-04	6	93	2	28437476
Pubmed	Varying modulation of HIV-1 LTR activity by Baf complexes.	SMARCA4 SMARCC2	1.05e-04	6	93	2	21699904
Pubmed	An in situ hybridization study of Runx2, Osterix, and Sox9 in the anlagen of mouse mandibular condylar cartilage in the early stages of embryogenesis.	IBSP SP7	1.05e-04	6	93	2	18624832
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	COL18A1 MYH6 AHNAK CFB	1.12e-04	92	93	4	37343697
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MSH6 TBC1D4 AHNAK SYNE2 SSX2IP TNRC6A GNL2 CPSF1 PPP6R1 ADGRL2 FTSJ3	1.14e-04	1049	93	11	27880917
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TPR MSH6 AHNAK SMARCA4 KMT2A BOD1L1 PCM1 TP53BP1	1.15e-04	549	93	8	38280479
Pubmed	The functional interactome landscape of the human histone deacetylase family.	TPR MSH6 SYNE2 CPSF1 PPP6R1 PHIP	1.30e-04	289	93	6	23752268
Pubmed	A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.	DCAF8 PHIP DCAF5	1.35e-04	37	93	3	16949367
Pubmed	Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA-dependent inhibition of chromatin remodeling.	SMARCA4 SMARCC2	1.47e-04	7	93	2	26138476
Pubmed	BRIT1/MCPH1 links chromatin remodelling to DNA damage response.	SMARCA4 SMARCC2	1.47e-04	7	93	2	19525936
Pubmed	Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.	SMARCA4 SMARCC2	1.47e-04	7	93	2	28369036
Interaction	SIRT7 interactions	TPR MSH6 AHNAK SYNE2 INTS1 GNL2 SMARCA4 CPSF1 KMT2A SMARCC2 BOP1 PHIP DCAF5 PCM1 TP53BP1 FTSJ3	2.72e-07	744	93	16	int:SIRT7
Interaction	RCOR1 interactions	PHLDB3 TPR MSH6 SALL2 AHNAK SMARCA4 SMARCC2 PPP6R1 KAT14 PHIP PCM1 TP53BP1 SP7	4.29e-07	494	93	13	int:RCOR1
Interaction	KMT2B interactions	KANSL1 TNRC6A KMT2A BOD1L1 YY1 KAT14 SP7	2.36e-06	130	93	7	int:KMT2B
Interaction	H3C1 interactions	TPR MSH6 CENPT ANK2 AHNAK INTS1 GNL2 SMARCA4 KMT2A SMARCC2 YY1 KAT14 PHIP TP53BP1 DNAH1 FTSJ3	3.35e-06	901	93	16	int:H3C1
Interaction	ASH2L interactions	KANSL1 TNRC6A KMT2A BOD1L1 KMT2E YY1 KAT14 TP53BP1 SP7	3.77e-06	265	93	9	int:ASH2L
Interaction	KAT8 interactions	TPR KANSL1 KMT2A YY1 KAT14 TP53BP1	5.12e-06	95	93	6	int:KAT8
Interaction	KDM1A interactions	PHLDB3 TPR MSH6 SALL2 TBC1D4 KANSL1 AHNAK SSX2IP TNRC6A SMARCC2 TACC1 PPP6R1 KAT14 PCM1 TP53BP1 SP7	5.82e-06	941	93	16	int:KDM1A
Interaction	NAA40 interactions	TPR MSH6 WASHC2C ANK2 AHNAK GNL2 SMARCA4 KMT2A BOD1L1 TACC1 PPP6R1 PCM1 AKAP12 TP53BP1 AHNAK2 FTSJ3	9.45e-06	978	93	16	int:NAA40
Interaction	KDM6A interactions	MSH6 KANSL1 SMARCA4 KMT2A BOD1L1 KAT14 SP7	1.01e-05	162	93	7	int:KDM6A
Interaction	SETD1A interactions	KANSL1 AHNAK KMT2A BOD1L1 YY1 KAT14 TP53BP1	1.38e-05	170	93	7	int:SETD1A
Interaction	HSPA12B interactions	PLEKHG4 PPP6R1 ADGRL2 AKAP12 FTSJ3	1.45e-05	67	93	5	int:HSPA12B
Interaction	KAT2A interactions	ATXN7L2 TACC1 YY1 KAT14 TP53BP1 MAPK8IP3 SP7	2.00e-05	180	93	7	int:KAT2A
Interaction	CSNK2A2 interactions	DNAAF2 MAF1 ABCA1 HIRIP3 SMARCA4 KMT2A BOP1 EFCAB14 ANKRD36 EIF3B TP53BP1 AHNAK2 SP7	2.51e-05	718	93	13	int:CSNK2A2
Interaction	PHF21A interactions	PHLDB3 TPR SALL2 TBC1D4 AHNAK TNRC6A PPP6R1 KAT14 PCM1	2.96e-05	343	93	9	int:PHF21A
Interaction	NUP43 interactions	CENPT SALL2 KANSL1 SYNE2 GNL2 SMARCA4 KMT2A BOP1 BOD1L1 PHIP AHNAK2 FTSJ3	3.00e-05	625	93	12	int:NUP43
Interaction	MECOM interactions	TPR MSH6 GNL2 SMARCA4 SMARCC2 YY1 PHIP TP53BP1 FTSJ3	4.13e-05	358	93	9	int:MECOM
Interaction	FGF14 interactions	PLEKHG4 PPP6R1 DCAF5 MAPK8IP3	4.16e-05	42	93	4	int:FGF14
Interaction	TADA3 interactions	ATXN7L2 KANSL1 KMT2A YY1 KAT14 TP53BP1	4.88e-05	141	93	6	int:TADA3
Interaction	RBBP5 interactions	KANSL1 TNRC6A GNL2 KMT2A SMARCC2 BOD1L1 YY1 KAT14	5.49e-05	287	93	8	int:RBBP5
Interaction	HCFC2 interactions	KANSL1 KMT2A BOD1L1 YY1 KAT14	6.73e-05	92	93	5	int:HCFC2
Interaction	RERE interactions	KANSL1 KMT2A KAT14 PHIP SP7	7.08e-05	93	93	5	int:RERE
Interaction	ZNF608 interactions	KANSL1 KMT2A KAT14 PHIP SP7	7.08e-05	93	93	5	int:ZNF608
Interaction	TAF9 interactions	ATXN7L2 ANK2 KMT2A YY1 KAT14 SP7	9.50e-05	159	93	6	int:TAF9
Interaction	SGF29 interactions	ATXN7L2 KANSL1 BOD1L1 YY1 KAT14 TP53BP1	1.13e-04	164	93	6	int:SGF29
Interaction	ING1 interactions	SALL2 WASHC2C SMARCA4 SMARCC2 SP7	1.15e-04	103	93	5	int:ING1
Interaction	CHAF1A interactions	MSH6 SMARCA4 CPSF1 SMARCC2 ATG14 EIF3B AKAP12 TP53BP1	1.22e-04	322	93	8	int:CHAF1A
Interaction	SCLT1 interactions	PHLDB3 SSX2IP TNRC6A WASHC2A PCM1 AKAP12	1.33e-04	169	93	6	int:SCLT1
Interaction	HDAC4 interactions	TPR DCAF8 KANSL1 WASHC2C SSX2IP BOP1 SMG5 EIF3B YY1 PHIP PCM1 TP53BP1	1.58e-04	744	93	12	int:HDAC4
Interaction	HDAC1 interactions	TPR MSH6 TBC1D4 AHNAK SYNE2 TNRC6A SMARCA4 KMT2A SMARCC2 PPP6R1 KMT2E YY1 KAT14 PCM1 FTSJ3	1.59e-04	1108	93	15	int:HDAC1
Interaction	CHD3 interactions	TPR MSH6 ZKSCAN1 GNL2 SMARCA4 CPSF1 KMT2A SMARCC2 EIF3B YY1 SP7 FTSJ3	1.85e-04	757	93	12	int:CHD3
Interaction	CPAP interactions	PHLDB3 IBSP SSX2IP TNRC6A WASHC2A PCM1	1.99e-04	182	93	6	int:CPAP
Interaction	GOLGA1 interactions	WASHC2C SSX2IP PPP6R1 WASHC2A PCM1 AHNAK2	2.05e-04	183	93	6	int:GOLGA1
Interaction	TOPBP1 interactions	MSH6 TBC1D4 SMARCA4 CLSTN1 TP53BP1	2.09e-04	117	93	5	int:TOPBP1
Interaction	KANSL2 interactions	KANSL1 KMT2A YY1 KAT14	3.09e-04	70	93	4	int:KANSL2
Interaction	KIF20A interactions	LPIN1 KIDINS220 ANK2 AHNAK SYNE2 TNRC6A SMARCA4 CPSF1 SMARCC2 BOP1 BOD1L1 PCM1 AHNAK2 FTSJ3	3.21e-04	1052	93	14	int:KIF20A
Interaction	H2BC8 interactions	MSH6 CENPT HIRIP3 INTS1 GNL2 SMARCA4 KMT2A SMARCC2 BOP1 PHIP	3.24e-04	576	93	10	int:H2BC8
Interaction	SLFN11 interactions	TPR SMARCA4 CPSF1 SMARCC2 EIF3B PHIP TP53BP1 FTSJ3	3.49e-04	376	93	8	int:SLFN11
Interaction	ACTC1 interactions	TPR MSH6 SYNE2 SMARCA4 CPSF1 SMARCC2 BOD1L1 EIF3B WASHC2A KAT14 TP53BP1	3.50e-04	694	93	11	int:ACTC1
Interaction	CENPA interactions	MSH6 CENPT HIRIP3 GNL2 KMT2A YY1 PHIP FTSJ3	3.55e-04	377	93	8	int:CENPA
Interaction	H2BC21 interactions	DNAAF2 MSH6 TBC1D4 HIRIP3 AHNAK SMARCA4 KMT2A SMARCC2 SMG5 KAT14 PHIP	3.59e-04	696	93	11	int:H2BC21
Interaction	POU5F1 interactions	DNAAF2 TPR MSH6 COL18A1 SALL2 AHNAK SMARCA4 CPSF1 SMARCC2 TP53BP1	3.61e-04	584	93	10	int:POU5F1
Interaction	CXXC1 interactions	KANSL1 KMT2A BOD1L1 YY1 KAT14	3.66e-04	132	93	5	int:CXXC1
Interaction	SIN3A interactions	SMARCA4 KMT2A SMARCC2 BOD1L1 KMT2E YY1 TP53BP1 SP7	3.75e-04	380	93	8	int:SIN3A
Interaction	MEX3A interactions	AHNAK SMARCA4 TACC1 EIF3B ADGRL2 CLSTN1 PCM1 AHNAK2	4.02e-04	384	93	8	int:MEX3A
Interaction	SETD1B interactions	KANSL1 KMT2A BOD1L1 KAT14	4.02e-04	75	93	4	int:SETD1B
Interaction	ADARB1 interactions	TPR ANK2 AHNAK IFRD2 GNL2 SMARCA4 SMARCC2 TP53BP1 FTSJ3	4.29e-04	489	93	9	int:ADARB1
Interaction	GALNTL5 interactions	AHNAK TP53BP1	4.36e-04	7	93	2	int:GALNTL5
Interaction	ZZZ3 interactions	KANSL1 KMT2A YY1 KAT14 TP53BP1	4.64e-04	139	93	5	int:ZZZ3
Interaction	H3C3 interactions	MSH6 GNL2 SMARCA4 KMT2A SMARCC2 BOP1 BOD1L1 YY1 PHIP	4.68e-04	495	93	9	int:H3C3
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	DCAF8 PHIP DCAF5	3.65e-05	18	66	3	498
GeneFamily	WASH complex	WASHC2C WASHC2A	1.95e-04	6	66	2	1331
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NEO1 IGFN1 HMCN2 ALPK3 CNTN6	3.03e-04	161	66	5	593
GeneFamily	Cadherin related	FAT2 CLSTN1	1.72e-03	17	66	2	24
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	DCAF8 IFRD2 INTS1 SMARCA4 SMG5 EIF3B CFAP410 MAPK8IP3 CAPN15 TECPR1	3.49e-07	338	93	10	M17094
Coexpression	STEIN_ESRRA_TARGETS_DN	MSH6 KIDINS220 BOP1 TACC1 EFCAB14 PHIP	2.06e-06	105	93	6	M18160
Coexpression	GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN	TBC1D4 KIDINS220 PPP6R1 EIF3B CAPN15 AHNAK2 FTSJ3	7.38e-06	200	93	7	M4538
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TPR KANSL1 AHNAK SYNE2 KMT2A BOD1L1 KMT2E PHIP PCM1	3.94e-10	200	93	9	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN1 ITGA11 FBXO41 KCNH4 CNTN6 STRIP2 SLC45A4	6.46e-08	168	93	7	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN1 ITGA11 FBXO41 KCNH4 CNTN6 STRIP2 SLC45A4	6.46e-08	168	93	7	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 CENPT CLIC6 AKAP12 TP53BP1 RUSC2	1.83e-06	175	93	6	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	KANSL1 TNRC6A TACC1 KMT2E PHIP PCM1	3.13e-06	192	93	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	ZKSCAN1 CPSF1 KMT2A BOD1L1 ANKRD36 AHNAK2	3.13e-06	192	93	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	KANSL1 AHNAK SYNE2 KMT2A ANKRD36 PCM1	3.13e-06	192	93	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	KANSL1 TNRC6A TACC1 KMT2E PHIP PCM1	3.22e-06	193	93	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERICH3 SERPINB11 AHNAK CLSTN1 CFB AHNAK2	3.63e-06	197	93	6	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	KIDINS220 ANK2 ZKSCAN1 KMT2A ANKRD36 KMT2E	3.73e-06	198	93	6	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Ptrf\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ITGA11 IGFN1 PLEKHG4 KCNH4 STRIP2	8.83e-06	133	93	5	a1bc34e5dda4ff4716b857931cc196f6770f58f4
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NPHP1 SALL2 PLEKHG4 GNL2 CLSTN1	1.53e-05	149	93	5	68661c8facfb638560bb2e2c20d509941286dacb
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MYH6 FAT2 KCNK13 SP7	1.96e-05	76	93	4	efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCell	Entopeduncular-Macroglia-OLIGODENDROCYTE-O1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	MYH6 FAT2 KCNK13 SP7	1.96e-05	76	93	4	254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	RIN1 COL18A1 HMCN2 ANK2 AKAP12	2.65e-05	167	93	5	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	FAT2 AHNAK SYNE2 ANKRD36 AKAP12	2.97e-05	171	93	5	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TPR TBC1D4 SYNE2 ANKRD36 PCM1	3.05e-05	172	93	5	9497948bbe53fb88c6ff6b347f743d456da587e5
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR MYH6 TBC1D4 AHNAK PCM1	3.40e-05	176	93	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 HMCN2 CDH12 AKAP12 AHNAK2	3.89e-05	181	93	5	3462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF469 HMCN2 CDH12 AKAP12 AHNAK2	3.89e-05	181	93	5	6730e249cac55ae892cc567d9211615882f3dab4
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPR AHNAK KMT2A PCM1 AKAP12	4.21e-05	184	93	5	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT2 SERPINB11 AHNAK CLSTN1 AHNAK2	4.32e-05	185	93	5	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RIN1 COL18A1 CENPT ARMCX4 SLC45A4	4.43e-05	186	93	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	KANSL1 SYNE2 KMT2A ANKRD36 TP53BP1	4.66e-05	188	93	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	COL18A1 ITGA11 ZNF469 ZKSCAN1 RUSC2	4.66e-05	188	93	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4\|GI_small-bowel / Manually curated celltypes from each tissue	ABCA1 NEO1 TBC1D4 AHNAK SYNE2	5.41e-05	194	93	5	4547b57669be5d4f0de55175802ee04372288a6a
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TBC1D4 SYNE2 KMT2A ANKRD36 KMT2E	5.54e-05	195	93	5	4bdedd924564a260841a9153604026b57487c83d
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE2 KMT2A ANKRD36 PCM1 AKAP12	5.82e-05	197	93	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	AHNAK GNL2 BOD1L1 ANKRD36 PHIP	5.82e-05	197	93	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	LPIN1 KANSL1 SYNE2 ANKRD36 PCM1	6.10e-05	199	93	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	mild-CD4+_Tcm\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TPR TBC1D4 SYNE2 KMT2A ANKRD36	6.10e-05	199	93	5	06c8a0e39f7a33736548f04a5e2263334c8541cf
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	KANSL1 AHNAK KMT2A CLSTN1 AKAP12	6.10e-05	199	93	5	174f6013af6eafa577f84205a62927f2b367fda3
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TPR SYNE2 BOD1L1 ANKRD36 KMT2E	6.10e-05	199	93	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT2 SERPINB11 AHNAK CLSTN1 AHNAK2	6.10e-05	199	93	5	ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TPR SYNE2 BOD1L1 YY1 AKAP12	6.10e-05	199	93	5	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FAT2 AHNAK SYNE2 CLSTN1 AHNAK2	6.25e-05	200	93	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	AHNAK SYNE2 KMT2A BOD1L1 TACC1	6.25e-05	200	93	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FAT2 AHNAK SYNE2 CLSTN1 AHNAK2	6.25e-05	200	93	5	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ITGA11 ABCA1 ANK2 TACC1 AKAP12	6.25e-05	200	93	5	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATXN7L2 SSX2IP CNTN6 AHNAK2	7.78e-05	108	93	4	d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCell	ASK428-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	TACC1 EFCAB14 AKAP12	7.99e-05	40	93	3	a0f60f893bea240775aa0af1d08474b73063019d
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PHLDB3 FAT2 CLIC6 AHNAK2	1.33e-04	124	93	4	b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCell	Endothelial-G\|World / shred on cell class and cell subclass (v4)	COL18A1 ABCA1 TBC1D4 PLEKHG4	1.33e-04	124	93	4	4b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PHLDB3 FAT2 CLIC6 AHNAK2	1.33e-04	124	93	4	231862f849d8ab73c6a44c782d33ef2f07661baf
Computational	Genes upregulated in subsets of cells of a given type within various tumors	MSH6 SYNE2 KMT2A PCM1	1.19e-04	50	55	4	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Disease	sick sinus syndrome (is_implicated_in)	MYH6 ANK2	9.15e-05	5	90	2	DOID:13884 (is_implicated_in)
Disease	palmitoyl dihydrosphingomyelin (d18:0/16:0) measurement	SYNE2 SMARCA4	1.91e-04	7	90	2	EFO_0800400
Disease	P wave terminal force measurement	MYH6 ALPK3	2.55e-04	8	90	2	EFO_0008379
Disease	triglycerides in large LDL measurement	ABCA1 SYNE2 TP53BP1	3.10e-04	43	90	3	EFO_0022319
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA4 SMARCC2	3.27e-04	9	90	2	DOID:0050340 (implicated_via_orthology)
Disease	saturated fatty acids measurement	ABCA1 SMARCA4 TP53BP1	3.55e-04	45	90	3	EFO_0022304
Disease	triglyceride measurement, intermediate density lipoprotein measurement	ABCA1 SYNE2 SMARCA4 TP53BP1	3.78e-04	111	90	4	EFO_0004530, EFO_0008595
Disease	Primary Ciliary Dyskinesia	DNAAF2 GAS2L2 DNAH1	4.04e-04	47	90	3	C4551720
Disease	Intellectual Disability	COL18A1 KANSL1 SMARCC2 KMT2E YY1 PHIP MAPK8IP3	4.43e-04	447	90	7	C3714756
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	ABCA1 SYNE2 SMARCA4 TP53BP1 DNAH1	6.28e-04	224	90	5	EFO_0004530, EFO_0008317
Disease	docosahexaenoic acid measurement	ABCA1 KANSL1 SMARCA4 KAT14	6.28e-04	127	90	4	EFO_0007761
Disease	leukemia	MSH6 KMT2A KMT2E	6.42e-04	55	90	3	C0023418
Disease	triglycerides in LDL measurement	ABCA1 SYNE2 TP53BP1	6.77e-04	56	90	3	EFO_0022320
Disease	Coffin-Siris syndrome	SMARCA4 SMARCC2	7.02e-04	13	90	2	C0265338
Disease	Global developmental delay	INTS1 SMARCC2 KMT2E MAPK8IP3	7.47e-04	133	90	4	C0557874
Disease	ovarian neoplasm	MSH6 KANSL1 SMARCA4 TP53BP1	7.68e-04	134	90	4	C0919267
Disease	Malignant neoplasm of ovary	MSH6 KANSL1 SMARCA4 TP53BP1	8.34e-04	137	90	4	C1140680
Disease	Profound Mental Retardation	COL18A1 KANSL1 YY1 PHIP	8.81e-04	139	90	4	C0020796
Disease	Mental Retardation, Psychosocial	COL18A1 KANSL1 YY1 PHIP	8.81e-04	139	90	4	C0025363
Disease	Mental deficiency	COL18A1 KANSL1 YY1 PHIP	8.81e-04	139	90	4	C0917816
Disease	cutaneous melanoma, hair color	AHNAK SYNE2 AKAP12	9.11e-04	62	90	3	EFO_0000389, EFO_0003924
Disease	intraocular pressure measurement	ZNF469 ABCA1 ELMO3 GNL2 KMT2A BOD1L1 MAPK8IP3	9.50e-04	509	90	7	EFO_0004695
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	ABCA1 SYNE2 SMARCA4 TP53BP1	1.00e-03	144	90	4	EFO_0004611, EFO_0020943
Disease	stem Cell Factor measurement	ABCA1 CENPT AHNAK2	1.14e-03	67	90	3	EFO_0008291
Disease	Muscle hypotonia	KANSL1 INTS1	1.21e-03	17	90	2	C0026827
Disease	level of Sphingomyelin (d32:1) in blood serum	SYNE2 SMARCA4	1.21e-03	17	90	2	OBA_2045173
Disease	Myeloid Leukemia	KMT2A KMT2E	1.36e-03	18	90	2	C0023470
Disease	Leukemia, Monocytic, Chronic	KMT2A KMT2E	1.36e-03	18	90	2	C0023466
Disease	intellectual disability (implicated_via_orthology)	KANSL1 ANK2 BOD1L1	1.58e-03	75	90	3	DOID:1059 (implicated_via_orthology)
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	ABCA1 SYNE2 SMARCA4 TP53BP1	1.69e-03	166	90	4	EFO_0004530, EFO_0004611
Disease	colorectal carcinoma (is_implicated_in)	MSH6 AKAP12	2.04e-03	22	90	2	DOID:0080199 (is_implicated_in)
Disease	HDL cholesterol change measurement	ABCA1 SYNE2	2.43e-03	24	90	2	EFO_0007805
Disease	breast cancer (implicated_via_orthology)	MSH6 SMARCA4	2.64e-03	25	90	2	DOID:1612 (implicated_via_orthology)
Disease	Antiglaucoma preparations and miotics use measurement	ABCA1 KMT2A	2.85e-03	26	90	2	EFO_0009944
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	MSH6 SMARCA4	2.85e-03	26	90	2	C0009405
Disease	urate measurement, bone density	THAP4 SALL2 KIDINS220 CDH12 CFB AKAP12 DNAH1	2.88e-03	619	90	7	EFO_0003923, EFO_0004531
Disease	Neurodevelopmental Disorders	ANK2 KMT2A KMT2E	2.92e-03	93	90	3	C1535926

Protein segments in the cluster

Peptide	Gene	Start	Entry
DTNDSGVELGEESRS	TACC1	301	O75410
GVSDSEESVFSGLED	BOP1	51	Q14137
ATSEEGEAEGGVAVS	ERICH3	926	Q5RHP9
GVAVSDVGESEEEAS	ERICH3	936	Q5RHP9
GGETAETAAEEREVL	ERICH3	1346	Q5RHP9
SEGEEITAAPEREGT	CFAP410	136	O43822
AGTEASSEEVGIAEA	EIF3B	46	P55884
SSEEVGIAEAGPESE	EIF3B	51	P55884
GVAGESDESGDERVS	ATG14	411	Q6ZNE5
GAEEGTEASAAEETT	AKAP12	986	Q02952
STGTVISDVEEDAGE	SSX2IP	306	Q9Y2D8
VAEESGVDAETSDGT	ABCA1	1251	O95477
AAGDGEATTPEERES	ALPK3	1376	Q96L96
GSGSVVDSVTEEEGA	ACAP3	626	Q96P50
EDGVEGDLGETQSRT	AHNAK	136	Q09666
IGGSSSEDDAIVADA	ADGRL2	1291	O95490
GTSDEEDSVLGIARE	ANKRD36	861	A6QL64
STITREVEPEGDGAE	CLSTN1	686	O94985
AGDSVEAEGRVGDSV	CLIC6	176	Q96NY7
AGDSVDAEGRVGDSV	CLIC6	216	Q96NY7
AGDSVDAEGRVGDSV	CLIC6	236	Q96NY7
SESSSEEEEEFGVVG	EFCAB14	41	O75071
GDATTVESRLGAGEE	ARMCX4	1856	Q5H9R4
RGGTQASSEESEEEG	ATXN7L2	376	Q5T6C5
EATEGGTSRVEAGSS	CAPN15	301	O75808
TGGSEERGATVTEDS	ANK2	2286	Q01484
SSLTETIEGVDAEDG	CFB	236	P00751
EEEVGEGSSTESSRD	PHLDB3	56	Q6NSJ2
ASSESTGFGEERESI	KIDINS220	1756	Q9ULH0
GEEVTETAGEGSESI	GNL2	491	Q13823
GSTSGEESDLEREVS	HIRIP3	356	Q9BW71
EEEVEEESRSGGSGA	MAF1	226	Q9H063
EESRSGGSGAEETST	MAF1	231	Q9H063
LSTAGSEVIGDVDEG	MAPK8IP3	386	Q9UPT6
TPSGEAGSEEDDEVV	NFU1	156	Q9UMS0
RGLDEEGEEESSAGS	INTS1	2016	Q8N201
SVETREESEGTGGQR	DNAAF2	491	Q9NVR5
TILGGAEDSADEEVT	HMCN2	2546	Q8NDA2
EVVTATGDVRGAGTD	LOXHD1	46	Q8IVV2
IEISASSGSRVEDGE	ARNTL2	86	Q8WYA1
GLGSETSPTVDDEEE	CPSF1	731	Q10570
EEAEEEGVSGASLSS	PCM1	626	Q15154
SSGAEVESVEVVGGD	FAT2	281	Q9NYQ8
AGGSSTEDSRSEEVE	COL18A1	701	P39060
DEATRTSTSEGLEEG	KAT14	16	Q9H8E8
MSGAEEGRETSSGIE	DCAF8	26	Q5TAQ9
EGRETSSGIEVEASD	DCAF8	31	Q5TAQ9
ETSLVTGEADEGRAG	DCAF5	681	Q96JK2
AATVVDVDEVRGSGE	NPHS2	61	Q9NP85
DVDEVRGSGEEGTEV	NPHS2	66	Q9NP85
SSGGESDIEEEELTR	KANSL1	406	Q7Z3B3
DGDTSATESGDEVPV	KMT2E	186	Q8IZD2
RIVDGIEDSGSTAEA	KCNH4	826	Q9UQ05
GVDSGVESTSDGLRD	LPIN1	446	Q14693
SIETDGVAESDTDGR	KCNK13	326	Q9HB14
GSEITSVDIDGDGVT	ITGA11	481	Q9UKX5
TGTSESSVEARGSEE	GPR101	291	Q96P66
ISDSESDIGGSDVEF	MSH6	251	P52701
EEGSSDEISSGVGDS	MSH6	271	P52701
DEISSGVGDSESEGL	MSH6	276	P52701
EIRAGSISSEEVDGS	BOD1L1	1696	Q8NFC6
EGESAVTSTGITEDG	BOD1L1	1786	Q8NFC6
EGEDVVTSTGRGNEI	BOD1L1	1866	Q8NFC6
SSSAGSQGREEIVED	DNAH1	3976	Q9P2D7
EASRVDGASVGEEEE	GAS2L2	826	Q8NHY3
EVTEAEGSQGTAEAD	CENPT	366	Q96BT3
TVSDGGDGSSSEEIR	CNTN6	976	Q9UQ52
EVEGESSGAGLSADR	ELMO3	321	Q96BJ8
RHSTEGEEGDVSDVG	FBXO41	476	Q8TF61
GEEGDVSDVGSRTTE	FBXO41	481	Q8TF61
VSDVGSRTTESEAEG	FBXO41	486	Q8TF61
STTAEDSLGGDVVDE	IFRD2	116	Q12894
QLDGVDDGTESDTSV	KMT2A	2716	Q03164
DGAGTVFTIDETTGD	CDH12	96	P55289
AVTSEGAGEALESEE	IGFN1	721	Q86VF2
ISVRGDSEEASGAEE	SALL2	796	Q9Y467
ETVEDTNGSETGFRA	NPHP1	281	O15259
ETEEVAEAAGGSGRA	RUSC2	1246	Q8N2Y8
VVDIRGGDSDTSSEG	TRIM45	61	Q9H8W5
GAVTEEEGSGQSEAR	RIN1	711	Q13671
EEGSESEGSESSGRS	SMG5	621	Q9UPR3
TEEEEESAGDGERTL	STRIP2	371	Q9ULQ0
VTSEEGGVAERDASE	SYNE2	4086	Q8WXH0
ADESGDAQRGTVESS	PLEKHG4	76	Q58EX7
AGGSLEISDVTEDDA	NEO1	301	Q92859
GEEEGSESESRSVKV	SMARCA4	1581	P51532
EASSGTEAATGLEGE	FTSJ3	596	Q8IY81
GEEESVTGANAEDTT	IBSP	201	P21815
EEGTEAAAATGDSIA	SERPINB11	341	Q96P15
EEISERLEEAGGATS	MYH6	1146	P13533
AGTTSDEPERIEESG	SMARCC2	741	Q8TAQ2
TEDTEQGREGEATAT	AHNAK2	606	Q8IVF2
LDGEEARTISGGEEA	APOBR	296	Q0VD83
ARTISGGEEAETASG	APOBR	301	Q0VD83
GDTESEEGEGETTVR	SLC45A4	481	Q5BKX6
EIENGSSSSDEGEVV	PHIP	811	Q8WWQ0
EGEVVAVSGGTSEEE	PHIP	821	Q8WWQ0
LGEGRSTGEEEASQT	SP7	391	Q8TDD2
VFVEAESEGISSEAG	TPR	2266	P12270
DEVRGSGESAPSDTD	TECPR1	401	Q7Z6L1
SGLGAGRTAEDTVED	TECPR1	446	Q7Z6L1
VQTREEVVGGDDSDG	YY1	106	P25490
SEEGSVGSDRGSIVD	WASHC2C	206	Q9Y4E1
EEGSSGSEVEEIPET	TP53BP1	656	Q12888
EIRQDTASESSDGEG	TBC1D4	731	O60343
GVRSGGSTDSEDEEE	PPP6R1	661	Q9UPN7
AEAESVGRVELGTGT	ZNF469	1561	Q96JG9
SEEGSVGSDRGSIVD	WASHC2A	206	Q641Q2
AETSEDSASRGETTG	ZKSCAN1	281	P17029
DAGDESATSSIEGGV	THAP4	196	Q8WY91
TESTGRLEEKGTGES	TNRC6A	676	Q8NDV7