Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	HSPG2 THBS1 THBS2 COL19A1 LAMA3 NID1 MUC2	7.15e-07	188	54	7	GO:0005201
GeneOntologyMolecularFunction	collagen binding	HSPG2 THBS1 NID1 USH2A CRTAP	2.62e-06	81	54	5	GO:0005518
GeneOntologyMolecularFunction	collagen V binding	HSPG2 THBS1	7.14e-05	5	54	2	GO:0070052
GeneOntologyMolecularFunction	methylated histone binding	TTLL12 KDM5A ING5 ING4	8.61e-05	86	54	4	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	TTLL12 KDM5A ING5 ING4	9.41e-05	88	54	4	GO:0140034
GeneOntologyMolecularFunction	calcium ion binding	JAG2 HSPG2 THBS1 THBS2 NOTCH2NLB MEGF8 SLIT1 NID1 CRB1	1.64e-04	749	54	9	GO:0005509
GeneOntologyMolecularFunction	modification-dependent protein binding	TTLL12 KDM5A OTUD7A ING5 ING4	2.33e-04	206	54	5	GO:0140030
GeneOntologyMolecularFunction	histone H4K20 methyltransferase activity	TTLL12 PRDM6	3.19e-04	10	54	2	GO:0042799
GeneOntologyMolecularFunction	proteoglycan binding	THBS1 SLIT1 NID1	3.55e-04	51	54	3	GO:0043394
GeneOntologyMolecularFunction	histone modifying activity	TTLL12 KDM5A ING4 EZH1 PRDM6	3.80e-04	229	54	5	GO:0140993
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO4A1 SLCO1B3	6.40e-04	14	54	2	GO:0015132
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO4A1 SLCO1B3	7.37e-04	15	54	2	GO:0071714
GeneOntologyMolecularFunction	histone binding	TTLL12 KDM5A ING5 ING4 EZH1	7.37e-04	265	54	5	GO:0042393
GeneOntologyMolecularFunction	protein-lysine N-methyltransferase activity	TTLL12 EZH1 PRDM6	8.27e-04	68	54	3	GO:0016279
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP12 LRP6	8.41e-04	16	54	2	GO:0005041
GeneOntologyMolecularFunction	lysine N-methyltransferase activity	TTLL12 EZH1 PRDM6	8.63e-04	69	54	3	GO:0016278
GeneOntologyMolecularFunction	histone methyltransferase activity	TTLL12 EZH1 PRDM6	9.38e-04	71	54	3	GO:0042054
GeneOntologyMolecularFunction	Wnt receptor activity	LRP6 NID1	9.51e-04	17	54	2	GO:0042813
GeneOntologyMolecularFunction	histone H4 methyltransferase activity	TTLL12 PRDM6	9.51e-04	17	54	2	GO:0140939
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO4A1 SLCO1B3	1.07e-03	18	54	2	GO:0015347
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP12 LRP6	1.46e-03	21	54	2	GO:0030228
GeneOntologyMolecularFunction	Notch binding	JAG2 NOTCH2NLB	2.41e-03	27	54	2	GO:0005112
GeneOntologyMolecularFunction	structural molecule activity	MPP2 HSPG2 THBS1 THBS2 COL19A1 LAMA3 NID1 MUC2	2.56e-03	891	54	8	GO:0005198
GeneOntologyMolecularFunction	methyltransferase activity	TTLL12 EZH1 PRDM15 PRDM6	2.62e-03	213	54	4	GO:0008168
GeneOntologyMolecularFunction	protein methyltransferase activity	TTLL12 EZH1 PRDM6	2.73e-03	103	54	3	GO:0008276
GeneOntologyMolecularFunction	N-methyltransferase activity	TTLL12 EZH1 PRDM6	2.88e-03	105	54	3	GO:0008170
GeneOntologyMolecularFunction	transferase activity, transferring one-carbon groups	TTLL12 EZH1 PRDM15 PRDM6	3.14e-03	224	54	4	GO:0016741
GeneOntologyMolecularFunction	laminin binding	THBS1 NID1	3.81e-03	34	54	2	GO:0043236
GeneOntologyMolecularFunction	Wnt-protein binding	LRP6 NID1	3.81e-03	34	54	2	GO:0017147
GeneOntologyMolecularFunction	fibronectin binding	THBS1 LOXL3	4.74e-03	38	54	2	GO:0001968
GeneOntologyMolecularFunction	enzyme inhibitor activity	THBS1 KDM5A SERPINB4 LRP6 SLCO1B3	6.31e-03	435	54	5	GO:0004857
GeneOntologyBiologicalProcess	DNA replication-dependent chromatin disassembly	ING5 ING4	2.09e-05	3	55	2	GO:0140889
GeneOntologyBiologicalProcess	extracellular matrix organization	HSPG2 ADAMTSL1 COL19A1 NID1 LOXL3 ADAMTSL3 CRTAP	6.15e-05	377	55	7	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	HSPG2 ADAMTSL1 COL19A1 NID1 LOXL3 ADAMTSL3 CRTAP	6.25e-05	378	55	7	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	HSPG2 ADAMTSL1 COL19A1 NID1 LOXL3 ADAMTSL3 CRTAP	6.36e-05	379	55	7	GO:0045229
GeneOntologyBiologicalProcess	animal organ morphogenesis	JAG2 HSPG2 TSHZ3 THBS1 NTNG2 MEGF8 SLIT1 SLC4A10 LAMA3 LRP6 USH2A CRB1	1.04e-04	1269	55	12	GO:0009887
GeneOntologyCellularComponent	extracellular matrix	HSPG2 LAMB4 THBS1 THBS2 ADAMTSL1 FCGBP COL19A1 LAMA3 NID1 LOXL3 ADAMTSL3 MUC2 USH2A	1.10e-08	656	55	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	HSPG2 LAMB4 THBS1 THBS2 ADAMTSL1 FCGBP COL19A1 LAMA3 NID1 LOXL3 ADAMTSL3 MUC2 USH2A	1.14e-08	658	55	13	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	HSPG2 LAMB4 THBS1 THBS2 ADAMTSL1 COL19A1 LAMA3 NID1 LOXL3 MUC2 USH2A	1.09e-07	530	55	11	GO:0062023
GeneOntologyCellularComponent	basement membrane	HSPG2 LAMB4 THBS2 LAMA3 NID1 USH2A	8.01e-07	122	55	6	GO:0005604
Domain	EGF_1	JAG2 HGFAC HSPG2 LAMB4 THBS1 THBS2 NTNG2 MEGF8 SLIT1 LAMA3 LRP6 NID1 USH2A CRB1	1.09e-14	255	54	14	PS00022
Domain	EGF	JAG2 HGFAC HSPG2 THBS1 THBS2 NTNG2 FCGBP MEGF8 SLIT1 LAMA3 LRP6 NID1 CRB1	9.97e-14	235	54	13	SM00181
Domain	EGF-like_dom	JAG2 HGFAC HSPG2 THBS1 THBS2 NTNG2 FCGBP MEGF8 SLIT1 LAMA3 LRP6 NID1 CRB1	2.10e-13	249	54	13	IPR000742
Domain	EGF-like_CS	JAG2 HGFAC HSPG2 LAMB4 THBS1 THBS2 NTNG2 MEGF8 SLIT1 LAMA3 LRP6 NID1 CRB1	3.83e-13	261	54	13	IPR013032
Domain	EGF_2	JAG2 HGFAC HSPG2 LAMB4 THBS1 THBS2 NTNG2 MEGF8 SLIT1 LAMA3 LRP6 NID1 CRB1	4.65e-13	265	54	13	PS01186
Domain	Laminin_G	HSPG2 THBS1 THBS2 COL19A1 SLIT1 LAMA3 USH2A CRB1	4.87e-12	58	54	8	IPR001791
Domain	EGF_3	JAG2 HGFAC HSPG2 THBS1 THBS2 NTNG2 MEGF8 SLIT1 LRP6 NID1 CRB1	5.89e-11	235	54	11	PS50026
Domain	EGF	JAG2 HGFAC HSPG2 THBS2 NTNG2 SLIT1 LRP6 NID1 CRB1	8.93e-11	126	54	9	PF00008
Domain	EGF_LAM_2	HSPG2 LAMB4 NTNG2 MEGF8 LAMA3 USH2A	2.47e-10	30	54	6	PS50027
Domain	EGF_LAM_1	HSPG2 LAMB4 NTNG2 MEGF8 LAMA3 USH2A	2.47e-10	30	54	6	PS01248
Domain	-	HSPG2 THBS1 THBS2 COL19A1 SLIT1 LAMA3 USH2A CRB1	2.85e-10	95	54	8	2.60.120.200
Domain	Laminin_EGF	HSPG2 LAMB4 NTNG2 MEGF8 LAMA3 USH2A	6.68e-10	35	54	6	PF00053
Domain	EGF_Lam	HSPG2 LAMB4 NTNG2 MEGF8 LAMA3 USH2A	6.68e-10	35	54	6	SM00180
Domain	Laminin_EGF	HSPG2 LAMB4 NTNG2 MEGF8 LAMA3 USH2A	1.13e-09	38	54	6	IPR002049
Domain	EGF_CA	JAG2 HSPG2 THBS1 THBS2 MEGF8 SLIT1 NID1 CRB1	2.13e-09	122	54	8	SM00179
Domain	EGF-like_Ca-bd_dom	JAG2 HSPG2 THBS1 THBS2 MEGF8 SLIT1 NID1 CRB1	2.42e-09	124	54	8	IPR001881
Domain	VWC	JAG2 THBS1 THBS2 FCGBP MUC2	7.80e-08	38	54	5	SM00214
Domain	LAM_G_DOMAIN	HSPG2 SLIT1 LAMA3 USH2A CRB1	7.80e-08	38	54	5	PS50025
Domain	Laminin_G_2	HSPG2 SLIT1 LAMA3 USH2A CRB1	1.02e-07	40	54	5	PF02210
Domain	Laminin_N	LAMB4 NTNG2 LAMA3 USH2A	1.11e-07	16	54	4	IPR008211
Domain	LAMININ_NTER	LAMB4 NTNG2 LAMA3 USH2A	1.11e-07	16	54	4	PS51117
Domain	Laminin_N	LAMB4 NTNG2 LAMA3 USH2A	1.11e-07	16	54	4	PF00055
Domain	LamNT	LAMB4 NTNG2 LAMA3 USH2A	1.11e-07	16	54	4	SM00136
Domain	VWF_dom	JAG2 THBS1 THBS2 FCGBP MUC2	1.31e-07	42	54	5	IPR001007
Domain	LamG	HSPG2 SLIT1 LAMA3 USH2A CRB1	1.67e-07	44	54	5	SM00282
Domain	ConA-like_dom	HSPG2 THBS1 THBS2 COL19A1 SLIT1 LAMA3 USH2A CRB1	2.06e-07	219	54	8	IPR013320
Domain	Growth_fac_rcpt_	JAG2 HSPG2 MEGF8 SLIT1 LAMA3 NID1 CRB1	3.16e-07	156	54	7	IPR009030
Domain	VWFC_1	JAG2 THBS1 THBS2 MUC2	3.43e-06	36	54	4	PS01208
Domain	VWFC_2	JAG2 THBS1 THBS2 MUC2	4.28e-06	38	54	4	PS50184
Domain	EGF_CA	JAG2 THBS1 THBS2 MEGF8 NID1	4.87e-06	86	54	5	PF07645
Domain	EGF_3	THBS2 MEGF8 NID1	4.93e-06	12	54	3	PF12947
Domain	EGF_dom	THBS2 MEGF8 NID1	4.93e-06	12	54	3	IPR024731
Domain	EGF_Ca-bd_CS	JAG2 MEGF8 SLIT1 NID1 CRB1	8.80e-06	97	54	5	IPR018097
Domain	EGF_CA	JAG2 MEGF8 SLIT1 NID1 CRB1	9.73e-06	99	54	5	PS01187
Domain	EGF-type_Asp/Asn_hydroxyl_site	JAG2 MEGF8 SLIT1 NID1 CRB1	1.36e-05	106	54	5	IPR000152
Domain	VWC_out	JAG2 FCGBP MUC2	2.14e-05	19	54	3	SM00215
Domain	TSP_1	THBS1 THBS2 ADAMTSL1 ADAMTSL3	3.28e-05	63	54	4	PF00090
Domain	TSP1	THBS1 THBS2 ADAMTSL1 ADAMTSL3	3.71e-05	65	54	4	SM00209
Domain	TSP1_rpt	THBS1 THBS2 ADAMTSL1 ADAMTSL3	3.71e-05	65	54	4	IPR000884
Domain	TSP1	THBS1 THBS2 ADAMTSL1 ADAMTSL3	3.71e-05	65	54	4	PS50092
Domain	TSPN	THBS1 THBS2 COL19A1	3.88e-05	23	54	3	SM00210
Domain	hEGF	JAG2 SLIT1 CRB1	7.11e-05	28	54	3	PF12661
Domain	ING	ING5 ING4	8.16e-05	5	54	2	SM01408
Domain	ING_N_histone_binding	ING5 ING4	8.16e-05	5	54	2	IPR024610
Domain	TSP_3	THBS1 THBS2	8.16e-05	5	54	2	PF02412
Domain	ING	ING5 ING4	8.16e-05	5	54	2	PF12998
Domain	TSP3	THBS1 THBS2	8.16e-05	5	54	2	PS51234
Domain	TSP_CTER	THBS1 THBS2	8.16e-05	5	54	2	PS51236
Domain	-	THBS1 THBS2	8.16e-05	5	54	2	4.10.1080.10
Domain	Thrombospondin_C	THBS1 THBS2	8.16e-05	5	54	2	IPR008859
Domain	TSP_C	THBS1 THBS2	8.16e-05	5	54	2	PF05735
Domain	Thrombospondin_3_rpt	THBS1 THBS2	8.16e-05	5	54	2	IPR017897
Domain	ING_fam	ING5 ING4	8.16e-05	5	54	2	IPR028651
Domain	Thrombospondin_3-like_rpt	THBS1 THBS2	8.16e-05	5	54	2	IPR003367
Domain	TSP_type-3_rpt	THBS1 THBS2	8.16e-05	5	54	2	IPR028974
Domain	ASX_HYDROXYL	JAG2 MEGF8 NID1 CRB1	1.99e-04	100	54	4	PS00010
Domain	LDLR_class-A_CS	HSPG2 LRP12 LRP6	2.09e-04	40	54	3	IPR023415
Domain	LAMININ_IVA	HSPG2 LAMA3	2.27e-04	8	54	2	PS51115
Domain	Laminin_B	HSPG2 LAMA3	2.27e-04	8	54	2	PF00052
Domain	LamB	HSPG2 LAMA3	2.27e-04	8	54	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA3	2.27e-04	8	54	2	IPR000034
Domain	Ldl_recept_a	HSPG2 LRP12 LRP6	2.97e-04	45	54	3	PF00057
Domain	SET	EZH1 PRDM15 PRDM6	3.18e-04	46	54	3	SM00317
Domain	-	HSPG2 LRP12 LRP6	3.18e-04	46	54	3	4.10.400.10
Domain	LDLRA_1	HSPG2 LRP12 LRP6	3.60e-04	48	54	3	PS01209
Domain	LDLRA_2	HSPG2 LRP12 LRP6	3.83e-04	49	54	3	PS50068
Domain	LDrepeatLR_classA_rpt	HSPG2 LRP12 LRP6	3.83e-04	49	54	3	IPR002172
Domain	LDLa	HSPG2 LRP12 LRP6	3.83e-04	49	54	3	SM00192
Domain	SET_dom	EZH1 PRDM15 PRDM6	4.07e-04	50	54	3	IPR001214
Domain	SET	EZH1 PRDM15 PRDM6	4.07e-04	50	54	3	PS50280
Domain	Fol_N	FCGBP SLIT1	4.44e-04	11	54	2	IPR003645
Domain	FOLN	FCGBP SLIT1	4.44e-04	11	54	2	SM00274
Domain	TIL	FCGBP MUC2	5.32e-04	12	54	2	PF01826
Domain	OA_transporter	SLCO4A1 SLCO1B3	5.32e-04	12	54	2	IPR004156
Domain	C8	FCGBP MUC2	5.32e-04	12	54	2	PF08742
Domain	OATP	SLCO4A1 SLCO1B3	5.32e-04	12	54	2	PF03137
Domain	Unchr_dom_Cys-rich	FCGBP MUC2	6.27e-04	13	54	2	IPR014853
Domain	C8	FCGBP MUC2	6.27e-04	13	54	2	SM00832
Domain	PLAC	ADAMTSL1 ADAMTSL3	7.30e-04	14	54	2	PF08686
Domain	TIL_dom	FCGBP MUC2	7.30e-04	14	54	2	IPR002919
Domain	Ldl_recept_b	LRP6 NID1	7.30e-04	14	54	2	PF00058
Domain	LDLRB	LRP6 NID1	7.30e-04	14	54	2	PS51120
Domain	-	IQSEC3 PSD2	8.41e-04	15	54	2	1.10.1000.11
Domain	Sec7	IQSEC3 PSD2	8.41e-04	15	54	2	PF01369
Domain	Sec7_alpha_orthog	IQSEC3 PSD2	8.41e-04	15	54	2	IPR023394
Domain	LY	LRP6 NID1	8.41e-04	15	54	2	SM00135
Domain	LDLR_classB_rpt	LRP6 NID1	8.41e-04	15	54	2	IPR000033
Domain	Zinc_finger_PHD-type_CS	KDM5A ING5 ING4	8.79e-04	65	54	3	IPR019786
Domain	Sec7	IQSEC3 PSD2	9.59e-04	16	54	2	SM00222
Domain	VWD	FCGBP MUC2	9.59e-04	16	54	2	SM00216
Domain	VWF_type-D	FCGBP MUC2	9.59e-04	16	54	2	IPR001846
Domain	SEC7	IQSEC3 PSD2	9.59e-04	16	54	2	PS50190
Domain	VWFD	FCGBP MUC2	9.59e-04	16	54	2	PS51233
Domain	Sec7_dom	IQSEC3 PSD2	9.59e-04	16	54	2	IPR000904
Domain	VWD	FCGBP MUC2	9.59e-04	16	54	2	PF00094
Domain	CTCK_1	SLIT1 MUC2	1.22e-03	18	54	2	PS01185
Domain	PHD	KDM5A ING5 ING4	1.33e-03	75	54	3	PF00628
Domain	PLAC	ADAMTSL1 ADAMTSL3	1.36e-03	19	54	2	PS50900
Domain	PLAC	ADAMTSL1 ADAMTSL3	1.36e-03	19	54	2	IPR010909
Domain	Znf_PHD-finger	KDM5A ING5 ING4	1.55e-03	79	54	3	IPR019787
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	HSPG2 LAMB4 THBS1 THBS2 LAMA3	3.72e-06	84	40	5	M7098
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THBS1 THBS2 ADAMTSL1 ADAMTSL3	4.25e-06	39	40	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THBS1 THBS2 ADAMTSL1 ADAMTSL3	4.25e-06	39	40	4	MM15165
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THBS1 THBS2 ADAMTSL1 ADAMTSL3 MUC2	1.34e-05	109	40	5	MM15164
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	HSPG2 THBS1 COL19A1 LAMA3 NID1 LOXL3 CRTAP	1.88e-05	300	40	7	M610
Pathway	PID_INTEGRIN1_PATHWAY	THBS1 THBS2 LAMA3 NID1	3.53e-05	66	40	4	M18
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THBS1 THBS2 ADAMTSL1 ADAMTSL3	3.97e-05	68	40	4	M27303
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	HSPG2 THBS1 THBS2 ADAMTSL1 ADAMTSL3	4.95e-05	143	40	5	M27275
Pathway	REACTOME_LAMININ_INTERACTIONS	HSPG2 LAMA3 NID1	8.15e-05	30	40	3	M27216
Pathway	REACTOME_COLLAGEN_FORMATION	COL19A1 LAMA3 LOXL3 CRTAP	1.19e-04	90	40	4	M631
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLC28A1 SLCO4A1 SLCO1B3	2.09e-04	41	40	3	MM15075
Pathway	REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES	SLC28A1 SLCO4A1 SLCO1B3	2.41e-04	43	40	3	M881
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	THBS1 THBS2 ADAMTSL1 ADAMTSL3	2.67e-04	111	40	4	M27416
Pathway	REACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO	SLIT1 ROBO3	3.48e-04	10	40	2	M27348
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO4A1 SLCO1B3	4.25e-04	11	40	2	M930
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO4A1 SLCO1B3	5.09e-04	12	40	2	MM15476
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	HSPG2 THBS1 LAMA3	6.16e-04	59	40	3	M27218
Pathway	REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX	HSPG2 COL19A1 LAMA3 NID1	6.45e-04	140	40	4	M587
Pathway	REACTOME_DISEASES_OF_METABOLISM	HSPG2 THBS1 THBS2 ADAMTSL1 ADAMTSL3	6.68e-04	250	40	5	M27554
Pathway	WP_SULFATASE_AND_AROMATASE_PATHWAY	SLCO4A1 SLCO1B3	6.99e-04	14	40	2	M48085
Pathway	WP_AXON_GUIDANCE	NTNG2 SLIT1 ROBO3	1.10e-03	72	40	3	M48335
Pathway	KEGG_TGF_BETA_SIGNALING_PATHWAY	AMHR2 THBS1 THBS2	1.84e-03	86	40	3	M2642
Pathway	KEGG_FOCAL_ADHESION	LAMB4 THBS1 THBS2 LAMA3	2.37e-03	199	40	4	M7253
Pathway	REACTOME_VISUAL_PHOTOTRANSDUCTION	METAP1 HSPG2 LRP12	2.83e-03	100	40	3	M27158
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	HSPG2 THBS1 ADAMTSL1 LAMA3 NID1 MUC2	2.67e-07	167	55	6	22159717
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	HSPG2 LAMA3 NID1	8.15e-07	12	55	3	16750824
Pubmed	Basement membrane composition in the early mouse embryo day 7.	HSPG2 LAMA3 NID1	1.68e-06	15	55	3	15895400
Pubmed	Induced thrombospondin expression in the mouse pancreas during pancreatic injury.	THBS1 THBS2	2.46e-06	2	55	2	16181801
Pubmed	Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.	THBS1 THBS2	2.46e-06	2	55	2	17620335
Pubmed	Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.	THBS1 THBS2	2.46e-06	2	55	2	23660684
Pubmed	Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.	THBS1 THBS2	2.46e-06	2	55	2	39122122
Pubmed	Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.	THBS1 THBS2	2.46e-06	2	55	2	34425286
Pubmed	Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.	THBS1 THBS2	2.46e-06	2	55	2	22930728
Pubmed	Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.	THBS1 THBS2	2.46e-06	2	55	2	8126073
Pubmed	THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.	THBS1 THBS2	2.46e-06	2	55	2	38339060
Pubmed	Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.	FCGBP MUC2	2.46e-06	2	55	2	19432394
Pubmed	Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.	THBS1 THBS2	2.46e-06	2	55	2	33372257
Pubmed	An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.	THBS1 THBS2	2.46e-06	2	55	2	21762961
Pubmed	Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.	THBS1 THBS2	2.46e-06	2	55	2	9694593
Pubmed	The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.	THBS1 THBS2	2.46e-06	2	55	2	12213711
Pubmed	Thrombospondin expression in aldosterone-producing adenomas.	THBS1 THBS2	2.46e-06	2	55	2	12358136
Pubmed	A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.	THBS1 THBS2	2.46e-06	2	55	2	1712771
Pubmed	Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.	THBS1 THBS2	2.46e-06	2	55	2	10027393
Pubmed	The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.	FCGBP MUC2	2.46e-06	2	55	2	34126068
Pubmed	Crystal structure and mutational analysis of a perlecan-binding fragment of nidogen-1.	HSPG2 NID1	2.46e-06	2	55	2	11427896
Pubmed	Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.	THBS1 THBS2	2.46e-06	2	55	2	33981184
Pubmed	Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.	THBS1 THBS2	2.46e-06	2	55	2	18594557
Pubmed	Structural basis for the high-affinity interaction of nidogen-1 with immunoglobulin-like domain 3 of perlecan.	HSPG2 NID1	2.46e-06	2	55	2	11574465
Pubmed	Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.	THBS1 THBS2	2.46e-06	2	55	2	15037577
Pubmed	TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.	THBS1 THBS2	2.46e-06	2	55	2	30928339
Pubmed	Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.	THBS1 THBS2	2.46e-06	2	55	2	17143334
Pubmed	Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.	THBS1 THBS2	2.46e-06	2	55	2	33759165
Pubmed	Application of a high-throughput genotyping method for loci exclusion in non-consanguineous Australian pedigrees with autosomal recessive retinitis pigmentosa.	USH2A CRB1	2.46e-06	2	55	2	22876132
Pubmed	A crucial role for Arf6 in the response of commissural axons to Slit.	IQSEC3 PSD2 ROBO3	3.56e-06	19	55	3	30674481
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	HSPG2 THBS1 THBS2 LAMA3 NID1	3.58e-06	146	55	5	27068509
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	THBS1 THBS2 ADAMTSL1 ADAMTSL3	6.26e-06	75	55	4	20637190
Pubmed	Increased sensitivity to kindling in mice lacking TSP1.	THBS1 THBS2	7.36e-06	3	55	2	26241338
Pubmed	Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.	THBS1 THBS2	7.36e-06	3	55	2	9373030
Pubmed	Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.	THBS1 THBS2	7.36e-06	3	55	2	18787106
Pubmed	Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.	THBS1 THBS2	7.36e-06	3	55	2	18032585
Pubmed	Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.	THBS1 THBS2	7.36e-06	3	55	2	19818485
Pubmed	EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.	THBS1 THBS2	7.36e-06	3	55	2	17638877
Pubmed	TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.	THBS1 THBS2	7.36e-06	3	55	2	30939949
Pubmed	EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5.	ING5 ING4	7.36e-06	3	55	2	21177815
Pubmed	Interactions between CD47 and thrombospondin reduce inflammation.	THBS1 THBS2	7.36e-06	3	55	2	17442977
Pubmed	Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.	THBS1 THBS2	7.36e-06	3	55	2	19004835
Pubmed	Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.	THBS1 THBS2	7.36e-06	3	55	2	8463250
Pubmed	Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.	THBS1 THBS2	7.36e-06	3	55	2	12482844
Pubmed	Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.	THBS1 THBS2	7.36e-06	3	55	2	26168731
Pubmed	Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.	THBS1 THBS2	7.36e-06	3	55	2	16598380
Pubmed	Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.	THBS1 THBS2	7.36e-06	3	55	2	27513329
Pubmed	Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.	THBS1 THBS2	7.36e-06	3	55	2	15347840
Pubmed	Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.	THBS1 THBS2	7.36e-06	3	55	2	25976449
Pubmed	The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.	THBS1 THBS2	7.36e-06	3	55	2	31092423
Pubmed	mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.	THBS1 THBS2	7.36e-06	3	55	2	34669362
Pubmed	Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.	THBS1 THBS2	7.36e-06	3	55	2	1459996
Pubmed	ADAMTSL-3/punctin-2, a novel glycoprotein in extracellular matrix related to the ADAMTS family of metalloproteases.	ADAMTSL1 ADAMTSL3	7.36e-06	3	55	2	14667842
Pubmed	Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.	THBS1 THBS2	7.36e-06	3	55	2	18178577
Pubmed	Differential expression of thrombospondin 1, 2, and 3 during murine development.	THBS1 THBS2	7.36e-06	3	55	2	8400410
Pubmed	Cocaine Triggers Astrocyte-Mediated Synaptogenesis.	THBS1 THBS2	7.36e-06	3	55	2	33069367
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	HSPG2 THBS1 LAMA3 NID1	7.70e-06	79	55	4	18757743
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	HSPG2 THBS1 ADAMTSL1 LAMA3 NID1	8.64e-06	175	55	5	28071719
Pubmed	Thrombospondin 2 potentiates notch3/jagged1 signaling.	THBS1 THBS2	1.47e-05	4	55	2	19147503
Pubmed	The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo.	HSPG2 NID1	1.47e-05	4	55	2	12588956
Pubmed	Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.	FCGBP MUC2	1.47e-05	4	55	2	28604600
Pubmed	Utility of molecular testing for related retinal dystrophies.	USH2A CRB1	1.47e-05	4	55	2	16767206
Pubmed	Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.	JAG2 MUC2	1.47e-05	4	55	2	22691042
Pubmed	Hbo1 Links p53-dependent stress signaling to DNA replication licensing.	ING5 ING4	1.47e-05	4	55	2	17954561
Pubmed	Multiple roles for slits in the control of cell migration in the rostral migratory stream.	SLIT1 ROBO3	1.47e-05	4	55	2	14960623
Pubmed	p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.	ING5 ING4	1.47e-05	4	55	2	12750254
Pubmed	Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.	THBS1 THBS2	1.47e-05	4	55	2	6338048
Pubmed	Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.	THBS1 THBS2	1.47e-05	4	55	2	18089612
Pubmed	Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.	THBS1 THBS2	1.47e-05	4	55	2	12909644
Pubmed	Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.	THBS1 THBS2	1.47e-05	4	55	2	11980922
Pubmed	Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.	THBS1 THBS2	1.47e-05	4	55	2	10900205
Pubmed	Expression patterns of Slit and Robo family members during vertebrate limb development.	SLIT1 ROBO3	1.47e-05	4	55	2	11472852
Pubmed	Spontaneous bacterial keratitis in CD36 knockout mice.	THBS1 THBS2	1.47e-05	4	55	2	20847111
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	JAG2 HSPG2 LRP12 THBS1 MEGF8 LRP6 NID1 LMBRD2 POGLUT2 CRTAP	1.65e-05	1201	55	10	35696571
Pubmed	Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.	THBS1 THBS2	2.45e-05	5	55	2	30622267
Pubmed	The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.	SLIT1 ROBO3	2.45e-05	5	55	2	15084255
Pubmed	The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.	HSPG2 NID1	2.45e-05	5	55	2	7670489
Pubmed	Mice deficient for the secreted glycoprotein SPARC/osteonectin/BM40 develop normally but show severe age-onset cataract formation and disruption of the lens.	HSPG2 NID1	2.45e-05	5	55	2	9524110
Pubmed	Conserved molecular interactions within the HBO1 acetyltransferase complexes regulate cell proliferation.	ING5 ING4	2.45e-05	5	55	2	22144582
Pubmed	Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens.	HSPG2 NID1	2.45e-05	5	55	2	12243745
Pubmed	Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan.	HSPG2 NID1	2.45e-05	5	55	2	11493006
Pubmed	Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.	LAMA3 NID1	2.45e-05	5	55	2	11829758
Pubmed	Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.	THBS1 THBS2	2.45e-05	5	55	2	23806329
Pubmed	Autocrine/juxtaparacrine regulation of axon fasciculation by Slit-Robo signaling.	SLIT1 ROBO3	3.67e-05	6	55	2	22306607
Pubmed	Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis.	HSPG2 NID1	3.67e-05	6	55	2	22753893
Pubmed	The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin.	HSPG2 NID1	3.67e-05	6	55	2	11956183
Pubmed	Nidogen-2: a new basement membrane protein with diverse binding properties.	HSPG2 NID1	3.67e-05	6	55	2	9733643
Pubmed	Robo2 Receptor Gates the Anatomical Divergence of Neurons Derived From a Common Precursor Origin.	SLIT1 ROBO3	3.67e-05	6	55	2	34249921
Pubmed	Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins.	HSPG2 NID1	3.67e-05	6	55	2	10544250
Pubmed	Esophageal muscle physiology and morphogenesis require assembly of a collagen XIX-rich basement membrane zone.	COL19A1 NID1	3.67e-05	6	55	2	15302855
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	HSPG2 THBS1 THBS2 NID1 LOXL3	4.61e-05	248	55	5	24006456
Pubmed	ING4 and ING5 are essential for histone H3 lysine 14 acetylation and epicardial cell lineage development.	ING5 ING4	5.13e-05	7	55	2	38446206
Pubmed	ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.	ING5 ING4	5.13e-05	7	55	2	16728974
Pubmed	Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice.	HSPG2 THBS1	5.13e-05	7	55	2	12242711
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	HGFAC HSPG2 THBS1 FCGBP MEGF8	5.45e-05	257	55	5	16335952
Pubmed	Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development.	HSPG2 NID1	6.83e-05	8	55	2	12015298
Pubmed	The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor.	HSPG2 NID1	6.83e-05	8	55	2	11847210
Pubmed	Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.	SLCO4A1 SLCO1B3	6.83e-05	8	55	2	19129463
Pubmed	Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.	THBS1 THBS2	6.83e-05	8	55	2	24460873
Pubmed	Slit2 and Robo3 modulate the migration of GnRH-secreting neurons.	SLIT1 ROBO3	6.83e-05	8	55	2	22912413
Interaction	SIRPD interactions	JAG2 HSPG2 THBS1 MEGF8 LRP6	3.07e-06	86	53	5	int:SIRPD
Interaction	EDN3 interactions	JAG2 HSPG2 MEGF8 LRP6 POGLUT2	9.42e-06	108	53	5	int:EDN3
Interaction	TAFAZZIN interactions	MEGF8 LAMA3 SLCO4A1 LRP6 NID1 POGLUT2	1.68e-05	207	53	6	int:TAFAZZIN
Interaction	IGFL3 interactions	JAG2 LRP12 LAMA3 LOXL3	4.51e-05	75	53	4	int:IGFL3
Interaction	LOXL3 interactions	HSPG2 LOXL3 POGLUT2	5.98e-05	29	53	3	int:LOXL3
Interaction	COL4A3 interactions	HSPG2 NID1 USH2A	6.63e-05	30	53	3	int:COL4A3
Interaction	PRELP interactions	HSPG2 MEGF8 NID1	8.07e-05	32	53	3	int:PRELP
Interaction	MSTN interactions	JAG2 MEGF8 POGLUT2	8.86e-05	33	53	3	int:MSTN
Interaction	PRG2 interactions	JAG2 HSPG2 THBS1 LRP6 POGLUT2 CRTAP	9.97e-05	285	53	6	int:PRG2
Cytoband	19q12	TSHZ3 MEGF8	2.55e-04	20	54	2	19q12
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	IQSEC3 KDM5A LRP6 ING4	8.03e-04	353	54	4	chr12p13
GeneFamily	ADAMTS like	ADAMTSL1 ADAMTSL3	8.50e-05	7	37	2	947
GeneFamily	Laminin subunits	LAMB4 LAMA3	2.66e-04	12	37	2	626
GeneFamily	Low density lipoprotein receptors	LRP12 LRP6	3.13e-04	13	37	2	634
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 ADAMTSL1 ROBO3 ADAMTSL3	3.18e-04	161	37	4	593
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM15 PRDM6	5.44e-04	17	37	2	1197
GeneFamily	PHD finger proteins	KDM5A ING5 ING4	8.20e-04	90	37	3	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	EZH1 PRDM6	2.19e-03	34	37	2	487
GeneFamily	Immunoglobulin like domain containing	HSPG2 ROBO3 ADAMTSL3	7.13e-03	193	37	3	594
GeneFamily	Solute carriers	SLC28A1 SLC4A10 SLCO4A1 SLCO1B3	8.39e-03	395	37	4	752
Coexpression	NABA_MATRISOME	HGFAC HSPG2 LAMB4 THBS1 THBS2 ADAMTSL1 NTNG2 COL19A1 MEGF8 SERPINB4 SLIT1 LAMA3 NID1 LOXL3 ADAMTSL3 MUC2 USH2A	8.92e-12	1026	53	17	M5889
Coexpression	NABA_CORE_MATRISOME	HSPG2 LAMB4 THBS1 THBS2 NTNG2 COL19A1 SLIT1 LAMA3 NID1 USH2A	1.80e-10	275	53	10	M5884
Coexpression	NABA_BASEMENT_MEMBRANES	HSPG2 LAMB4 NTNG2 LAMA3 NID1 USH2A	1.86e-10	40	53	6	M5887
Coexpression	NABA_MATRISOME	HGFAC HSPG2 THBS1 THBS2 ADAMTSL1 NTNG2 COL19A1 MEGF8 SERPINB4 SLIT1 LAMA3 NID1 LOXL3 ADAMTSL3 MUC2	8.53e-10	1008	53	15	MM17056
Coexpression	NABA_ECM_GLYCOPROTEINS	LAMB4 THBS1 THBS2 NTNG2 SLIT1 LAMA3 NID1 USH2A	5.63e-09	196	53	8	M3008
Coexpression	NABA_CORE_MATRISOME	HSPG2 THBS1 THBS2 NTNG2 COL19A1 SLIT1 LAMA3 NID1	6.78e-08	270	53	8	MM17057
Coexpression	HEBERT_MATRISOME_TNBC_BONE_BRAIN_LIVER_LUNG_METASTASTASES	HSPG2 ADAMTSL1 NID1	2.20e-06	13	53	3	M48004
Coexpression	NABA_ECM_GLYCOPROTEINS	THBS1 THBS2 NTNG2 SLIT1 LAMA3 NID1	2.39e-06	191	53	6	MM17059
Coexpression	LIM_MAMMARY_STEM_CELL_UP	HGFAC HSPG2 TSHZ3 THBS1 PSD2 LAMA3 POGLUT2 RUSC2	5.06e-06	479	53	8	M2573
Coexpression	LIM_MAMMARY_STEM_CELL_UP	HGFAC HSPG2 TSHZ3 THBS1 PSD2 LAMA3 POGLUT2 RUSC2	5.37e-06	483	53	8	MM1082
Coexpression	NABA_MATRISOME_BLEO_FIBROTIC_LUNG	HSPG2 LAMA3 NID1	8.69e-06	20	53	3	MM17053
Coexpression	HEBERT_MATRISOME_TNBC_LUNG_METASTASIS	HSPG2 LAMA3 NID1	1.34e-05	23	53	3	M48001
ToppCell	facs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 AMHR2 THBS1 THBS2 FCGBP TNFRSF4	7.03e-08	175	54	6	21542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell	P15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AMHR2 ADAMTSL1 PIERCE1 SLCO4A1 ADAMTSL3	1.81e-06	167	54	5	5c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 ADAMTSL1 NID1 ADAMTSL3 PRDM6	2.41e-06	177	54	5	9ec7f1e64312d26d434b3312b58386715dbad644
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 ADAMTSL1 NID1 ADAMTSL3 PRDM6	2.41e-06	177	54	5	016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	HSPG2 THBS2 NID1 ROBO3 POGLUT2	2.99e-06	185	54	5	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 THBS1 ADAMTSL1 NID1 CRTAP	3.24e-06	188	54	5	b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	THBS1 THBS2 NID1 ADAMTSL3 PRDM6	3.41e-06	190	54	5	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	droplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 THBS1 THBS2 FCGBP TNFRSF4	3.41e-06	190	54	5	c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 THBS2 NID1 ADAMTSL3	3.59e-06	192	54	5	671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 ADAMTSL1 NID1 ADAMTSL3	3.59e-06	192	54	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 ADAMTSL1 NID1 ADAMTSL3	3.59e-06	192	54	5	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 ADAMTSL1 NID1 ADAMTSL3	3.59e-06	192	54	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	facs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 THBS2 NID1 ADAMTSL3	3.59e-06	192	54	5	840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell\|Adult / Lineage, Cell type, age group and donor	THBS2 ADAMTSL1 NID1 ADAMTSL3 PRDM6	3.59e-06	192	54	5	d21f0f577156f17c899b08871046a26b88aea011
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 ADAMTSL1 NID1 LOXL3 CRTAP	3.68e-06	193	54	5	316ebdf15f75d88c348f909b643fcd315364ca84
ToppCell	droplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 ADAMTSL1 NID1 LOXL3 CRTAP	3.68e-06	193	54	5	1afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCell	ILEUM-inflamed-(8)_Smooth_muscle_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LAMB4 TSHZ3 NID1 ADAMTSL3 PRDM6	3.68e-06	193	54	5	084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THBS2 ADAMTSL1 NID1 ADAMTSL3 PRDM6	3.68e-06	193	54	5	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	droplet-Fat-Scat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 ADAMTSL1 NID1 LOXL3 CRTAP	3.68e-06	193	54	5	8dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MPP2 THBS2 ADAMTSL1 NID1 ADAMTSL3	3.87e-06	195	54	5	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS2 NID1 PRDM6 CRTAP	3.87e-06	195	54	5	223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TSHZ3 THBS1 THBS2 ADAMTSL3 PRDM6	4.17e-06	198	54	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 THBS2 NID1 ADAMTSL3 PRDM6	4.37e-06	200	54	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 THBS2 NID1 ADAMTSL3 PRDM6	4.37e-06	200	54	5	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 THBS2 NID1 ADAMTSL3 PRDM6	4.37e-06	200	54	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS2 ADAMTSL1 NID1 ADAMTSL3 PRDM6	4.37e-06	200	54	5	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	Pericytes-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	TSHZ3 THBS2 SLIT1 ADAMTSL3	3.30e-05	150	54	4	dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCell	Basal_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 TSHZ3 COL19A1 LAMA3	3.47e-05	152	54	4	72499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell	PBMC-Control-cDC_2\|Control / Compartment, Disease Groups and Clusters	AMHR2 OTUD7A PRDM6 TNFRSF4	3.56e-05	153	54	4	4ee37266b0054f276c7a73ab9220f681b9d74c71
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DRD2 LRP6 NID1 ADAMTSL3	3.94e-05	157	54	4	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D122\|Adult / Lineage, Cell type, age group and donor	MPP2 ADAMTSL1 NID1 PRDM6	4.24e-05	160	54	4	fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCell	ICU-SEP-Lymphocyte-T_NK-MAIT\|ICU-SEP / Disease, Lineage and Cell Type	LRP12 SLC4A10 POGLUT2 MOCOS	4.67e-05	164	54	4	db863a44fc0dad5518c47fdbf64ea21d6f36f089
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THBS2 OTUD7A NID1 PRDM6	4.89e-05	166	54	4	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FCGBP SLC4A10 LAMA3 ADAMTSL3	5.37e-05	170	54	4	5a64e05c263df915085988d881808221e2c0f2e2
ToppCell	343B-Fibroblasts-Fibroblast-H-\|343B / Donor, Lineage, Cell class and subclass (all cells)	TTLL12 TSHZ3 THBS2 PRDM6	5.88e-05	174	54	4	2627c3983009839fedbc5e3f628739dc026447f4
ToppCell	343B-Fibroblasts-Fibroblast-H\|343B / Donor, Lineage, Cell class and subclass (all cells)	TTLL12 TSHZ3 THBS2 PRDM6	5.88e-05	174	54	4	507a33e58f62e2b72f0bcc743e84dbd0bf705a15
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	THBS2 ADAMTSL1 ADAMTSL3 USH2A	6.14e-05	176	54	4	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPP2 THBS1 NID1 ADAMTSL3	6.28e-05	177	54	4	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ZNF16 LMBRD2 PRDM15 RUSC2	6.28e-05	177	54	4	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZNF16 LMBRD2 PRDM15 RUSC2	6.42e-05	178	54	4	9d575902d3dbe33437c9d4200df093a741269803
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	THBS1 THBS2 ADAMTSL1 NID1	6.42e-05	178	54	4	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	ZNF16 LMBRD2 PRDM15 RUSC2	6.42e-05	178	54	4	536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HGFAC HSPG2 IQSEC3 POGLUT2	6.56e-05	179	54	4	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 THBS1 THBS2 NID1	6.70e-05	180	54	4	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 THBS1 THBS2 NID1	6.70e-05	180	54	4	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	TCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	KDM5A LRP6 ING4 LOXL3	6.70e-05	180	54	4	886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 HSPG2 LAMB4 TNFRSF4	6.85e-05	181	54	4	7d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THBS1 THBS2 NID1 ADAMTSL3	6.85e-05	181	54	4	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 ADAMTSL1 NID1 ADAMTSL3	7.00e-05	182	54	4	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 ADAMTSL1 NID1 ADAMTSL3	7.00e-05	182	54	4	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSPG2 THBS2 NID1 ADAMTSL3	7.00e-05	182	54	4	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL19A1 SLC28A1 SLCO4A1 USH2A	7.15e-05	183	54	4	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-large_intestine_goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC AMHR2 THBS1 FCGBP	7.15e-05	183	54	4	ee9c88be88221b7ad4ea9f890b17d6156fb3432e
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Goblet_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGFAC AMHR2 THBS1 FCGBP	7.15e-05	183	54	4	c52b84034503d931f7b87312d2ff86daff14152d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THBS2 ADAMTSL1 NID1 ADAMTSL3	7.30e-05	184	54	4	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D122\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 NID1 ADAMTSL3 PRDM6	7.30e-05	184	54	4	2b7e6f91e11c228f0521e099886867d9e998e78d
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 NID1 LOXL3 PRDM6	7.30e-05	184	54	4	d754c3de621429b220ae4ac426cdfc619e848462
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	THBS2 ADAMTSL1 ADAMTSL3 PRDM6	7.45e-05	185	54	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JAG2 HSPG2 PSD2 TNFRSF4	7.45e-05	185	54	4	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac\|normal_Pleural_Fluid / Location, Cell class and cell subclass	LRP12 THBS1 NOTCH2NLB LOXL3	7.61e-05	186	54	4	3314def702fe6a5056d0dadbb3a587c5d1a16412
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LAMB4 THBS1 LAMA3 USH2A	7.61e-05	186	54	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Smooth_muscle_cells\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LAMB4 TSHZ3 ADAMTSL3 PRDM6	7.61e-05	186	54	4	cacc2f0b2ed46516173b61ba1c5c226a2db7cddc
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	JAG2 HSPG2 PSD2 LAMA3	7.61e-05	186	54	4	a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	THBS1 THBS2 ADAMTSL1 NID1	7.77e-05	187	54	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 THBS1 THBS2 FCGBP	7.77e-05	187	54	4	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	JAG2 HSPG2 ADAMTSL1 TNFRSF4	7.93e-05	188	54	4	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 HSPG2 SLCO4A1 TNFRSF4	7.93e-05	188	54	4	a37edd8f9e4a4e336b5acbb0407d3d275975cee8
ToppCell	Control-Fibroblasts-Adventitial_FB\|Control / group, cell type (main and fine annotations)	THBS2 ADAMTSL1 NID1 ADAMTSL3	7.93e-05	188	54	4	706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 ADAMTSL1 COL19A1 PRDM6	7.93e-05	188	54	4	d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TSHZ3 COL19A1 ADAMTSL3 CRB1	8.10e-05	189	54	4	06c44746fa4f02e6e2b3b635cdf2d8dfef3754d3
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSHZ3 THBS2 NID1 ADAMTSL3	8.10e-05	189	54	4	6b3b42d758b63a0df62310c34fa3bde421c1afd7
ToppCell	droplet-Lung-LUNG-30m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSHZ3 THBS2 NID1 ADAMTSL3	8.10e-05	189	54	4	344b23d3c47d0665dda1cd4856a5e72f1c28cfb3
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPP2 NID1 LOXL3 ADAMTSL3	8.10e-05	189	54	4	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D175\|Adult / Lineage, Cell type, age group and donor	THBS2 ADAMTSL1 ADAMTSL3 PRDM6	8.26e-05	190	54	4	7dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 THBS2 NID1 ADAMTSL3	8.43e-05	191	54	4	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TSHZ3 COL19A1 ADAMTSL3 CRB1	8.43e-05	191	54	4	9c0ee270209b02043393416ecc9a81ddedfbb8b6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 THBS1 THBS2 NID1	8.60e-05	192	54	4	4022f208eb5db760abd0aac782a25e8ab63efc64
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSHZ3 THBS2 NID1 CRTAP	8.60e-05	192	54	4	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAMTSL1 NID1 LOXL3	8.60e-05	192	54	4	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAMTSL1 NID1 LOXL3	8.60e-05	192	54	4	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THBS1 THBS2 NID1 PRDM6	8.60e-05	192	54	4	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 SLCO4A1 NID1	8.60e-05	192	54	4	a42aed9e563f5f4af029b8804c104f11ad227a8f
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THBS2 ADAMTSL1 ADAMTSL3 PRDM6	8.60e-05	192	54	4	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TSHZ3 THBS1 THBS2 NID1	8.60e-05	192	54	4	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSHZ3 THBS2 NID1 CRTAP	8.60e-05	192	54	4	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	THBS2 ADAMTSL1 ADAMTSL3 PRDM6	8.60e-05	192	54	4	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TSHZ3 COL19A1 ADAMTSL3 CRB1	8.78e-05	193	54	4	d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 THBS2 ADAMTSL1 PRDM6	8.78e-05	193	54	4	9d0b966d13cbce97beb43de6dc77f006c363a181
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 THBS2 ADAMTSL1 ADAMTSL3	8.78e-05	193	54	4	64edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 THBS2 NID1	8.78e-05	193	54	4	49600db68ed65cafc67bd45a285b364e4f5f88af
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	THBS1 THBS2 NID1 ADAMTSL3	8.78e-05	193	54	4	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 THBS1 THBS2 NID1	8.78e-05	193	54	4	45b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCell	facs-SCAT-Fat-3m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 ADAMTSL1 NID1 LOXL3	8.95e-05	194	54	4	14b614f039bc866a1348a2728a68b7d254c7748c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 ADAMTSL1 NID1 LOXL3	8.95e-05	194	54	4	68c7bfead1158641928cc276f599b4a79e06c73c
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	THBS2 NID1 ADAMTSL3 PRDM6	8.95e-05	194	54	4	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	JAG2 HSPG2 ADAMTSL1 NID1	8.95e-05	194	54	4	8a4be91414a2e69dd410aa75791f16008204c9a1
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS2 ADAMTSL1 NID1 LOXL3	8.95e-05	194	54	4	f6aeae6a1e4017e341323fd4784c9e3bae00552b
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 ADAMTSL1 NID1 CRTAP	9.13e-05	195	54	4	69a29d03e664b72f32d41876510c62345c3aed31
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS1 THBS2 NID1 PRDM6	9.13e-05	195	54	4	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	JAG2 HSPG2 ADAMTSL1 LRP6	9.13e-05	195	54	4	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
Drug	Urapidil hydrochloride [64887-14-5]; Up 200; 9.4uM; HL60; HT_HG-U133A	JAG2 MPP2 HSPG2 LAMB4 THBS1 DRD2 COL19A1	3.35e-07	195	53	7	3078_UP
Drug	Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; PC3; HT_HG-U133A	JAG2 MPP2 LRP12 KDM5A PIERCE1 LRP6	6.18e-06	196	53	6	7142_DN
Drug	Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT_HG-U133A	MPP2 LRP12 DRD2 ING4 ROBO3 RUSC2	6.18e-06	196	53	6	4125_DN
Drug	kalinin	HSPG2 LAMB4 LAMA3 NID1	8.17e-06	55	53	4	CID000032518
Drug	m1 C	METAP1 THBS1 SERPINB4	5.63e-05	32	53	3	CID000448219
Drug	CID5311039	HSPG2 SLCO1B3 CRTAP	7.40e-05	35	53	3	CID005311039
Drug	Meclozine dihydrochloride [1104-22-9]; Up 200; 8.6uM; MCF7; HT_HG-U133A	LAMB4 RPAP1 NID1 ING4 RUSC2	8.36e-05	192	53	5	5607_UP
Drug	Ursolic acid [77-52-1]; Up 200; 8.8uM; PC3; HT_HG-U133A	DRD2 KDM5A PIERCE1 ING4 EZH1	8.57e-05	193	53	5	2067_UP
Drug	Clobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A	HGFAC DRD2 KDM5A SLC28A1 RUSC2	8.78e-05	194	53	5	6835_UP
Drug	Cinchonine [118-10-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	MPP2 DRD2 LAMA3 LRP6 ING4	8.78e-05	194	53	5	4107_DN
Drug	Thiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A	MPP2 HSPG2 THBS1 KDM5A ING4	9.00e-05	195	53	5	2875_DN
Drug	(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ZNF16 LRP12 ING4 ROBO3 EZH1	9.00e-05	195	53	5	4980_DN
Drug	Methacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	DRD2 KDM5A ING4 ROBO3 EZH1	9.22e-05	196	53	5	7321_UP
Drug	Methoxamine hydrochloride [61-16-5]; Down 200; 16.2uM; MCF7; HT_HG-U133A	ZNF16 LAMB4 RPAP1 LRP6 EZH1	9.22e-05	196	53	5	4972_DN
Drug	Sotalol hydrochloride [959-24-0]; Down 200; 13uM; MCF7; HT_HG-U133A	MPP2 LRP12 DRD2 LAMA3 EZH1	9.44e-05	197	53	5	4160_DN
Drug	Sulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A	JAG2 HSPG2 KDM5A ING4 EZH1	9.44e-05	197	53	5	2814_DN
Drug	(+,-)-Synephrine [94-07-5]; Up 200; 24uM; MCF7; HT_HG-U133A	MPP2 ZNF16 LRP12 DRD2 RUSC2	9.44e-05	197	53	5	6798_UP
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; MCF7; HT_HG-U133A	HSPG2 ZNF16 LRP12 KDM5A LRP6	9.44e-05	197	53	5	4363_DN
Drug	Cephalexin monohydrate [23325-78-2]; Up 200; 11uM; MCF7; HT_HG-U133A	HSPG2 LRP12 COL19A1 MEGF8 NID1	9.44e-05	197	53	5	5250_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A	MPP2 ZNF16 LRP12 RPAP1 KDM5A	9.67e-05	198	53	5	6983_UP
Drug	Amiprilose hydrochloride [60414-06-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A	LRP12 DRD2 ING4 EZH1 RUSC2	9.90e-05	199	53	5	4119_DN
Drug	Timolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A	LAMB4 DRD2 MEGF8 MUC2 RUSC2	9.90e-05	199	53	5	5280_UP
Drug	Vitexin [3681-93-4]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MPP2 HSPG2 LAMB4 LRP12 DRD2	1.01e-04	200	53	5	4413_DN
Drug	Promethazine hydrochloride [58-33-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A	LRP12 DRD2 SLC28A1 ING4 ADAMTSL3	1.01e-04	200	53	5	6477_UP
Drug	Val-Val	THBS1 THBS2 DRD2	1.03e-04	39	53	3	CID000107475
Drug	Rgds Peptide	THBS1 THBS2 LAMA3 NID1	1.09e-04	106	53	4	CID000107775
Disease	squamous cell carcinoma (implicated_via_orthology)	ING5 ING4	9.13e-06	3	52	2	DOID:1749 (implicated_via_orthology)
Disease	melanoma (implicated_via_orthology)	ING5 ING4	8.47e-05	8	52	2	DOID:1909 (implicated_via_orthology)
Disease	Retinitis pigmentosa	TOPORS USH2A CRB1	3.06e-04	74	52	3	cv:C0035334
Disease	Diabetic Angiopathies	THBS1 THBS2	3.60e-04	16	52	2	C0011875
Disease	Microangiopathy, Diabetic	THBS1 THBS2	3.60e-04	16	52	2	C0025945
Disease	Retinitis Pigmentosa	TOPORS USH2A CRB1	8.29e-04	104	52	3	C0035334
Disease	Ciliopathies	TOPORS USH2A CRB1	9.75e-04	110	52	3	C4277690
Disease	retinitis pigmentosa (implicated_via_orthology)	USH2A CRB1	1.04e-03	27	52	2	DOID:10584 (implicated_via_orthology)
Disease	adult onset asthma	ADAMTSL3 MUC2 GPANK1	1.19e-03	118	52	3	EFO_1002011
Disease	cranial vault morphology measurement	ADAMTSL1 LAMA3 ADAMTSL3	1.28e-03	121	52	3	EFO_0009278
Disease	chronic obstructive pulmonary disease	MPP2 TSHZ3 ADAMTSL1 RPAP1 ADAMTSL3 PRDM15	1.29e-03	688	52	6	EFO_0000341

Protein segments in the cluster

Peptide	Gene	Start	Entry
CGTDFCNANYSHLPP	AMHR2	111	Q16671
QCYDSSPCERQPCQH	HSPG2	4101	P98160
TPAHALQCRDGYEPC	NOTCH2NLB	21	P0DPK3
PDNCITSCDRLNFHP	PIERCE1	111	Q5BN46
CSHSQDAGVRCNLPY	LOXL3	396	P58215
CYPRSDRCNYQNHCP	LRP12	426	Q9Y561
HLACIARNCYPSPLN	METAP1	171	P53582
FCDYCNSEDPRKAHP	LAMA3	101	Q16787
PTPSLQYCENCDTHF	GPANK1	211	O95872
LCPGNHPDASCRDTY	ERVS71-1	131	P61550
NDCLPDPCHSRGRCY	JAG2	676	Q9Y219
LQECNLDPCPASDGY	ADAMTSL1	351	Q8N6G6
ECPSHREYQACGPAE	MUC2	4761	Q02817
CQPSRCHPDAFCYNT	NID1	806	P14543
HPRATCLNTPLSYEC	MEGF8	1086	Q7Z7M0
CPAHYSLNADNRTCS	LRP6	916	O75581
SASNPDCQLPHLFCY	MOCOS	186	Q96EN8
DCQLPHLFCYPAQSN	MOCOS	191	Q96EN8
CHFDYDPARDSLIPC	MPP2	256	Q14168
PNRCHCSPLVLAYDQ	OTUD7A	351	Q8TE49
SNTQDPQSYHCSCPR	HGFAC	176	Q04756
ILSLPRYHCENPASC	IQSEC3	626	Q9UPP2
SCNPERLVCLYHPTD	KDM5A	691	P29375
NPDRPYQCGHCSQSF	PRDM6	496	Q9NQX0
GRCNPEDCLYPVSHA	COL19A1	1121	Q14993
ECPPNSHYELCADTC	FCGBP	1531	Q9Y6R7
EAFCHRNCSAAPQPE	CRTAP	81	O75718
VDPNEPTYCLCHQVS	ING5	181	Q8WYH8
CLCPDDPSSNQYFAH	LAMB4	911	A4D0S4
NIHCDCNIPPVLYSA	DRD2	396	P14416
PGNYTCHCPFDNLSR	CRB1	416	P82279
VDPNEPTYCLCHQVS	ING4	191	Q9UNL4
ERFCSHENPYLCSNE	NTNG2	66	Q96CW9
SPELDANCNSYRPHC	RUSC2	356	Q8N2Y8
ANCNSYRPHCEPCPA	RUSC2	361	Q8N2Y8
QRFCIQDCPYRSSHP	USH2A	81	O75445
YNLQELDPDGCSPCN	USH2A	681	O75445
YNRCKHAAANSSPPE	LMBRD2	61	Q68DH5
DCSQYHDSECPELGP	PRDM15	316	P57071
TAPCNAACSCQPEHY	SLCO4A1	501	Q96BD0
HRCENTDPGYNCLPC	THBS1	606	P07996
THFSRRYCQCNPDDS	PSD2	386	Q9BQI7
SCCPSNPDPDDRYYN	ROBO3	981	Q96MS0
LLTQYSCNCVEPHNP	SLC4A10	661	Q6U841
NYSAHLGECPRDNTC	SLCO1B3	516	Q9NPD5
YQPCDHPDRPCDSTC	EZH1	521	Q92800
SPSTNEEFCCNHPFL	SERPINB4	356	P48594
DLPSIRNCYLTHCSP	RPAP1	1051	Q9BWH6
VNFNPDCERACRYHP	TTLL12	606	Q14166
CPSYQNSPAAEFSCH	TSHZ3	56	Q63HK5
PVYHENCDCPLQDSA	POGLUT2	131	Q6UW63
SPEALDNCCRFYNHT	SLC28A1	631	O00337
YPSNDRCCHECRPGN	TNFRSF4	36	P43489
AAFDQHANYDCPAPS	TOPORS	366	Q9NS56
EAICPHYQQPDCDTR	ZNF16	56	P17020
EVGDRCDNCPYVHNP	THBS2	771	P35442
CDNCPYVHNPAQIDT	THBS2	776	P35442
HNDPLEVYRCACPSG	SLIT1	941	O75093
QNIRYKTCSNHDCPP	ADAMTSL3	111	P82987