Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V1B1 ATP6V1B2 ABCA1 MYO1A MYO1C VPS4A DHX35 DNAH5 HSPA1L DDX39B KIF25 DNHD1 DDX51 ORC4 HELZ2 ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

1.01e-0561421320GO:0140657
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCA1 VPS4A RAB40AL ERAS DHX35 RAB40B DNAH5 HSPA1L DDX39B KIF25 DDX51 RAB40A GFM2 ORC4 GTPBP2 HELZ2 RAB39A ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

3.01e-0577521322GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCA1 VPS4A RAB40AL ERAS DHX35 RAB40B DNAH5 HSPA1L DDX39B KIF25 DCP2 DDX51 RAB40A GFM2 ORC4 GTPBP2 HELZ2 RAB39A ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

3.39e-0583921323GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCA1 VPS4A RAB40AL ERAS DHX35 RAB40B DNAH5 HSPA1L DDX39B KIF25 DCP2 DDX51 RAB40A GFM2 ORC4 GTPBP2 HELZ2 RAB39A ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

3.45e-0584021323GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCA1 VPS4A RAB40AL ERAS DHX35 RAB40B DNAH5 HSPA1L DDX39B KIF25 DCP2 DDX51 RAB40A GFM2 ORC4 GTPBP2 HELZ2 RAB39A ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

3.45e-0584021323GO:0016818
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP6V1B1 ATP6V1B2 ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.13e-05622136GO:0019829
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 VPS4A DHX35 DNAH5 HSPA1L DDX39B KIF25 DDX51 ORC4 HELZ2 ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

8.30e-0544121315GO:0016887
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V1B1 ATP6V1B2 ABCA1 ATP1A4 ATP2A1 ATP2A2 ATP2A3

1.69e-041092137GO:0042626
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2A1 ATP2A2 ATP2A3

1.85e-04112133GO:0005388
GeneOntologyMolecularFunctionretinoic acid binding

RXRA UGT2B17 UGT1A4 IGF2R

2.11e-04282134GO:0001972
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.67e-04362134GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.67e-04362134GO:0015662
GeneOntologyMolecularFunctioncalcium-dependent ATPase activity

ATP2A1 ATP2A3

6.70e-0442132GO:0030899
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH5 KIF25 DNHD1

8.68e-04182133GO:0008569
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

CHM UCP1 UCP2 RAB40AL ERAS RAB40B NPR2 RAB40A GFM2 GTPBP2 GUCY2D PDE5A RAB39A

9.09e-0443921313GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

CHM UCP1 UCP2 RAB40AL ERAS RAB40B NPR2 RAB40A GFM2 GTPBP2 GUCY2D PDE5A RAB39A

9.09e-0443921313GO:0019001
GeneOntologyMolecularFunctionprotein geranylgeranyltransferase activity

CHM PGGT1B

1.11e-0352132GO:0004661
GeneOntologyMolecularFunctionoxidative phosphorylation uncoupler activity

UCP1 UCP2

1.11e-0352132GO:0017077
GeneOntologyCellularComponentnuclear envelope

CYBB LEMD3 VPS4A RRP12 MCM3AP RAB40AL UGT2B17 RAB40B RANBP2 SYNE1 RAB40A RIF1 RNF123 INTS5 IGF2R GUCY2D UGT2B11 ATP2A3

1.98e-0556021418GO:0005635
GeneOntologyCellularComponentplatelet dense tubular network membrane

ATP2A1 ATP2A2 ATP2A3

8.49e-0592143GO:0031095
GeneOntologyCellularComponentplatelet dense tubular network

ATP2A1 ATP2A2 ATP2A3

1.64e-04112143GO:0031094
GeneOntologyCellularComponentnuclear membrane

LEMD3 RRP12 MCM3AP UGT2B17 RANBP2 SYNE1 RIF1 RNF123 INTS5 GUCY2D UGT2B11 ATP2A3

2.69e-0434921412GO:0031965
DomainP-type_ATPase_IIA

ATP2A1 ATP2A2 ATP2A3

1.46e-0632133IPR005782
DomainATPase_P-typ_TM_dom

ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.69e-05162134IPR023298
Domain-

ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.69e-051621341.20.1110.10
DomainCation_ATPase_C

ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.48e-05172134PF00689
DomainATPase_P-typ_cation-transptr_C

ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.48e-05172134IPR006068
DomainCation_ATPase_N

ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.44e-05182134PF00690
DomainCation_ATPase_N

ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.44e-05182134SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A4 ATP2A1 ATP2A2 ATP2A3

5.57e-05192134IPR004014
DomainP-loop_NTPase

ATP6V1B1 ATP6V1B2 ABCA1 MYO1A MYO1C VPS4A SLFN14 RAB40AL ERAS DHX35 RAB40B DNAH5 DDX39B KIF25 DNHD1 DDX51 RAB40A GFM2 ORC4 GTPBP2 HELZ2 RAB39A YME1L1

1.09e-0484821323IPR027417
DomainNuc_recep-AF1

RXRA RXRG

1.29e-0422132PF11825
DomainNuc_recep-AF1

RXRA RXRG

1.29e-0422132IPR021780
DomainATPase_V1-cplx_bsu

ATP6V1B1 ATP6V1B2

1.29e-0422132IPR005723
DomainV-ATPase_su_B/beta

ATP6V1B1 ATP6V1B2

1.29e-0422132IPR022879
DomainHydrolase_3

ATP2A1 ATP2A2 ATP2A3

1.65e-04102133PF08282
DomainHAD-like_dom

PUDP ACAD10 ATP1A4 ATP2A1 ATP2A2 ATP2A3

2.85e-04792136IPR023214
Domain-

ATP6V1B1 ATP6V1B2 ABCA1 VPS4A SLFN14 RAB40AL ERAS DHX35 RAB40B DNAH5 DDX39B DNHD1 DDX51 RAB40A GFM2 ORC4 GTPBP2 HELZ2 RAB39A YME1L1

3.60e-04746213203.40.50.300
Domain-

ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.60e-043221343.40.1110.10
Domain-

ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.60e-043221342.70.150.10
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH3 ATP2A1 ATP2A2 ATP2A3

4.54e-05181624M614
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_SERCA

ATP2A1 ATP2A2 ATP2A3

8.00e-0581623M47955
PathwayBIOCARTA_G2_PATHWAY

CDKN1A WEE1 PRKDC CDC25C

1.05e-04221624MM1365
PathwayKEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY

RXRA RXRG ATP2A2

1.19e-0491623M47629
PathwayBIOCARTA_G2_PATHWAY

CDKN1A WEE1 PRKDC CDC25C

1.49e-04241624M8560
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EPPK1 MYO1C USP9X KRI1 EPB41L3 RRP12 MCM3AP BOP1 PTCD3 FLNA FLNC RANBP2 NSD2 PRDX4 DDX51 RIF1 IGF2R HELZ2 ATIC PRKDC ATP2A2 ZMYM3

1.98e-106532182222586326
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYO1C ACAT2 VPS4A EPB41L3 CXXC1 WASHC5 RRP12 MCM3AP AP1G2 BOP1 RIC8A HSPA1L DDX39B VARS1 PTCD3 FLNA FLNC RANBP2 NOB1 DDX51 RLF RIF1 FHOD1 ATIC PRKDC ATP2A2 YME1L1 ZMYM3

3.32e-0813532182829467282
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MYO1C VPS4A USP9X KRI1 EPB41L3 DHCR24 RRP12 BOP1 DNAH5 TALDO1 DDX39B VARS1 PTCD3 DNHD1 FLNA RANBP2 NSD2 SYNE1 PRDX4 PPAT STT3B RIF1 IGF2R PRKCI ATIC PRKDC PEAK1 ATP2A2

9.71e-0814252182830948266
Pubmed

The effects of the phenylalanine 256 to valine mutation on the sensitivity of sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) Ca2+ pump isoforms 1, 2, and 3 to thapsigargin and other inhibitors.

ATP2A1 ATP2A2 ATP2A3

2.43e-073218316410239
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ATP6V1B1 LEMD3 USP9X ACP2 PLD3 JAK1 PTPRM DHCR24 MCM3AP SGCE FKBP8 HSPA1L DDX39B NOTCH3 ACAD10 ORC4 RIF1 INTS5 IGF2R ZDHHC9 IPO13 PRKDC ATP2A3

2.74e-0710612182333845483
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

PLD3 EPB41L3 FKBP11 CXXC1 SACS RRP12 DHX35 CPSF2 DDX39B VARS1 ARHGEF6 PTCD3 FLNC RANBP2 NSD2 SYNE1 PRDX4 STT3B INTS5 HELZ2 PRKDC ATP2A2 ZMYM3

3.86e-0710822182338697112
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

VPS4A USP9X PKD1 FKBP8 HSPA1L B3GNT9 PRKDC ATP2A1 ATP2A2 ATP2A3

4.81e-071952181017110338
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ALKBH4 EPPK1 SPEG ANKLE1 CSAD RRP12 MCM3AP PKD1 AP1G2 RIC8A FLNA FLNC NSD2 NOB1 KCNH3 INTS5 IGF2R CELSR3 PLA2G4B HELZ2 PRKDC IL17RD ATP2A3

5.54e-0711052182335748872
Pubmed

Probing nuclear pore complex architecture with proximity-dependent biotinylation.

LEMD3 MCM3AP RANBP2 WEE1 SYNE1 GUCY2D PRKDC

5.72e-0777218724927568
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

CLSTN3 LEMD3 VPS4A USP9X PLD3 DHCR24 RRP12 RIC8A FKBP8 VARS1 FLNA RANBP2 STT3B INTS5 IGF2R RAB39A ATIC PRKDC ATP2A2 YME1L1 ZMYM3

5.96e-079422182131073040
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ATP6V1B2 MYO1C LEMD3 USP9X WDR55 KRI1 SNX19 ZYX PTPRM WASHC5 RRP12 FKBP8 CPSF2 RANBP2 NSD2 RIF1 IGF2R PRKCI PEAK1 CDC25C ATP2A2 YME1L1

8.76e-0710492182227880917
Pubmed

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

ATP2A1 ATP2A2 ATP2A3

9.67e-074218325110346
Pubmed

The nongastric H+-K+-ATPases: molecular and functional properties.

ATP2A1 ATP2A2 ATP2A3

9.67e-074218310362770
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

DNAH5 NOTCH3 STK25 CYP4V2 COL6A1 FLNA FLNC SYNE1 CARD8 RNF123

1.12e-062142181022199357
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

ATP6V1B1 ATP6V1B2 MYO1C SPINT1 ACAT2 CDHR2 VPS4A ACP2 PLD3 ITGAM MELTF FCGBP CAPN5 TALDO1 STK25 ATRN COL6A1 FLNA VTN SI IGF2R ATIC

1.21e-0610702182223533145
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

MYO1C USP9X PLD3 FKBP8 HSPA1L FLNA RANBP2 PRDX4 PRKDC ATP2A1 ATP2A2 YME1L1

2.08e-063442181236282215
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

LEMD3 USP9X JAK1 DHCR24 FBXW5 FLNA FLNC RANBP2 PRDX4 STT3B IGF2R PRKDC ATP2A2

2.11e-064082181333766124
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

EPPK1 MYO1C ZYX HSPA1L DDX39B VARS1 PTCD3 FLNA FLNC RANBP2 FHOD1 ATIC PRKDC ATP2A2

2.22e-064772181431300519
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ATP6V1B2 EPPK1 USP9X PLD3 SACS RRP12 BOP1 FKBP8 CPSF2 DDX39B VARS1 FLNA FLNC RANBP2 VTN SYNE1 RIF1 IGF2R ATIC PRKDC ATP2A2

2.23e-0610242182124711643
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40AL RAB40B RAB40A

2.41e-065218327909076
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

CLSTN3 LEMD3 PLD3 FKBP11 MELTF PDF RRP12 SGCE CPSF2 NOTCH3 ATRN COL6A1 B3GNT9 PRDX4 STT3B IGF2R CELSR3 FHOD1 SLITRK5 IPO13 ATP2A2 ATP2A3

7.67e-0612012182235696571
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

EPB41L3 LRRC3 SYNJ2 PKD1 NOTCH3 FLNA FLNC CELSR3 PRICKLE3 GUCY2D ATP2A3

8.29e-063292181117474147
Pubmed

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

ATP2A1 ATP2A2 ATP2A3

8.35e-067218324786561
Pubmed

Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.

ZYX SACS FLNC PRDX4 PRKDC ATP2A1

8.59e-0676218627542412
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYO1C ZYX RRP12 CPSF2 ARHGEF6 FLNA RANBP2 WEE1 DDX51 RIF1 INTS5 PRICKLE3 FHOD1 HELZ2 PRKDC ATP2A2 ZMYM3

8.92e-067742181715302935
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

EPPK1 USP9X JAK1 SACS DNAH5 DDX39B FLNA NSD2 HELZ2 PRKDC SEC14L5

9.03e-063322181137433992
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

PATZ1 USP9X KRI1 SYNJ2 RRP12 BOP1 FKBP8 PTCD3 NOB1 STT3B FHOD1 PRKDC ATP2A2 YME1L1

1.06e-055472181437267103
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

USP9X PLD3 ITGAM HSPA1L VARS1 FLNA FLNC PRDX4 LACC1 HELZ2 PRKDC

1.26e-053442181130333137
Pubmed

The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells.

CDKN1A WEE1 CDC25C

1.33e-05821839371520
Pubmed

Widespread control of calcium signaling by a family of SERCA-inhibiting micropeptides.

ATP2A1 ATP2A2 ATP2A3

1.33e-058218327923914
Pubmed

Gene knockout studies of Ca2+-transporting ATPases.

ATP2A1 ATP2A2 ATP2A3

1.33e-058218310951186
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

ATP2A1 ATP2A2 ATP2A3

1.33e-058218319033399
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

EPPK1 MYO1A MYO1C VPS4A PLD3 FKBP8 PTCD3 RANBP2 VTN PRKDC FBXO21 ATP2A1 ATP2A2 ATP2A3 YME1L1

1.63e-056472181526618866
Pubmed

A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.

ATP2A1 ATP2A2 ATP2A3

1.98e-059218325640239
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ATP6V1B2 CLSTN3 USP9X RXRG JAK1 SACS VPS35L PKD1 DHX35 VARS1 ATRN CFAP91 SYNE1 SLC4A3 RNF123 ACAD8 CELSR3 ASTN1 ATIC PRKDC ATP2A2 YME1L1

2.17e-0512852182235914814
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

ATP6V1B1 ATP6V1B2 MYO1C CDHR2 ACP2 PLD3 RUSC2 MELTF FCGBP PKD1 GATD1 CAPN5 DNHD1 ATRN COL6A1 FLNA IGF2R PRKCI ATIC

2.49e-0510162181919056867
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

CDKN1A LEMD3 METAP1D WASHC5 DHCR24 RRP12 VPS35L ATRN FLNA FLNC RANBP2 STT3B RLF RIF1 INTS5 IGF2R PRICKLE3 FHOD1 PRKDC ATP2A2 ZMYM3

2.54e-0512032182129180619
Pubmed

Enhancer activation requires trans-recruitment of a mega transcription factor complex.

RXRA RXRG PRKDC

2.82e-0510218325303530
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP1A4 ATP2A1 ATP2A2 ATP2A3

3.15e-0529218415071553
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ADGRB1 PLD3 JAK1 SACS DHCR24 PKD1 SLC9A7 FKBP8 SYNE1 SI SLC4A3 IPO13 IL17RD ATP2A1 ATP2A2

3.83e-056972181528298427
Pubmed

USP19 deubiquitinating enzyme supports cell proliferation by stabilizing KPC1, a ubiquitin ligase for p27Kip1.

HSPA1L FLNC RNF123

3.86e-0511218319015242
Pubmed

Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease.

COL6A1 CACNA1S ATP2A1

3.86e-0511218331199454
Pubmed

Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells.

CYBB ATP2A2

3.91e-052218224631774
Pubmed

Changes in V-ATPase subunits of human urinary exosomes reflect the renal response to acute acid/alkali loading and the defects in distal renal tubular acidosis.

ATP6V1B1 ATP6V1B2

3.91e-052218229310826
Pubmed

The mRNA expression levels of uncoupling proteins 1 and 2 in mononuclear cells from patients with metabolic disorders: obesity and type 2 diabetes mellitus.

UCP1 UCP2

3.91e-052218229151065
Pubmed

Role and mechanism of FLNa and UCP2 in the development of cervical cancer.

UCP2 FLNA

3.91e-052218233125133
Pubmed

Role of the Polymorphisms of Uncoupling Protein Genes in Childhood Obesity and Their Association with Obesity-Related Disturbances.

UCP1 UCP2

3.91e-052218228704105
Pubmed

Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1.

ATP2A2 ATP2A3

3.91e-052218219650915
Pubmed

Filamin A stimulates cdc25C function and promotes entry into mitosis.

FLNA CDC25C

3.91e-052218221325883
Pubmed

Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.

ITGAM SIGLEC15

3.91e-052218237311743
Pubmed

Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway.

CYBB ITGAM

3.91e-052218228978491
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

3.91e-052218210679933
Pubmed

The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study.

UCP1 UCP2

3.91e-052218217397545
Pubmed

Effect of chronic obstructive pulmonary disease on calcium pump ATPase expression in human diaphragm.

ATP2A1 ATP2A2

3.91e-052218215718407
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

3.91e-052218224469451
Pubmed

Atypical protein kinase Cλ is critical for growth factor receptor-induced dorsal ruffle turnover and cell migration.

RIC8A PRKCI

3.91e-052218224092753
Pubmed

Fatty acids are key in 4-hydroxy-2-nonenal-mediated activation of uncoupling proteins 1 and 2.

UCP1 UCP2

3.91e-052218224204965
Pubmed

Regulation of SERCA pumps expression in diabetes.

ATP2A2 ATP2A3

3.91e-052218225270119
Pubmed

UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis.

UCP1 ATP2A2

3.91e-052218229131158
Pubmed

Polyunsaturated fatty acids activate human uncoupling proteins 1 and 2 in planar lipid bilayers.

UCP1 UCP2

3.91e-052218217242157
Pubmed

Training induced decrease in oxygen cost of cycling is accompanied by down-regulation of SERCA expression in human vastus lateralis muscle.

ATP2A1 ATP2A2

3.91e-052218218953100
Pubmed

The association between gene polymorphisms in uncoupling proteins and hearing impairment in Japanese elderly.

UCP1 UCP2

3.91e-052218219895332
Pubmed

Myosin-1a is critical for normal brush border structure and composition.

MYO1A MYO1C

3.91e-052218215758024
Pubmed

SERCA overexpression reduces hydroxyl radical injury in murine myocardium.

ATP2A1 ATP2A2

3.91e-052218216798816
Pubmed

Complement receptor 3 deficiency influences lesion progression during Leishmania major infection in BALB/c mice.

ITGAM PRKDC

3.91e-052218219797068
Pubmed

Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.

ATP2A2 ATP2A3

3.91e-052218221885870
Pubmed

Blockade of class IA phosphoinositide 3-kinase in neutrophils prevents NADPH oxidase activation- and adhesion-dependent inflammation.

CYBB ITGAM

3.91e-052218217197441
Pubmed

Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms.

ATP6V1B1 ATP6V1B2

3.91e-05221827945239
Pubmed

Nox2 targets SERCA in response to a high fat high sugar diet.

CYBB ATP2A2

3.91e-052218224704899
Pubmed

Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit.

ATP6V1B1 ATP6V1B2

3.91e-052218217392376
Pubmed

Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2+ ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice.

ATP2A1 ATP2A2

3.91e-052218212556521
Pubmed

Atypical fast SERCA1a protein expression in slow myofibers and differential S-nitrosylation prevented by exercise during long term bed rest.

ATP2A1 ATP2A2

3.91e-052218219644701
Pubmed

Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice.

ATP6V1B1 ATP6V1B2

3.91e-052218217898041
Pubmed

Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA1 and -2) in human extraocular muscles.

ATP2A1 ATP2A2

3.91e-052218214638697
Pubmed

Transfer of type II collagen-induced arthritis from DBA/1 to severe combined immunodeficiency mice can be prevented by blockade of Mac-1.

ITGAM PRKDC

3.91e-05221828690467
Pubmed

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.

SYNE1 CSMD1

3.91e-052218224387768
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

3.91e-05221827689010
Pubmed

Multiple and diverse coexpression, location, and regulation of additional SERCA2 and SERCA3 isoforms in nonfailing and failing human heart.

ATP2A2 ATP2A3

3.91e-052218219962989
Pubmed

Association between functional genetic variants in retinoid X receptor-α/γ and the risk of gestational diabetes mellitus in a southern Chinese population.

RXRA RXRG

3.91e-052218234633445
Pubmed

SERCA1 truncated proteins unable to pump calcium reduce the endoplasmic reticulum calcium concentration and induce apoptosis.

ATP2A1 ATP2A2

3.91e-052218211402072
Pubmed

The retinoid X receptors and their ligands.

RXRA RXRG

3.91e-052218222020178
Pubmed

Thyroid hormone resistance and increased metabolic rate in the RXR-gamma-deficient mouse.

RXRA RXRG

3.91e-052218210880050
Pubmed

Presence of serum autoantibodies to vacuolar H+ -ATPase in patients with renal tubular acidosis.

ATP6V1B1 ATP6V1B2

3.91e-052218230821427
Pubmed

Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.

ATP2A1 ATP2A2

3.91e-052218210603953
Pubmed

Characterizing SERCA Function in Murine Skeletal Muscles after 35-37 Days of Spaceflight.

ATP2A1 ATP2A2

3.91e-052218234769190
Pubmed

Alterations in genes encoding sarcoplasmic-endoplasmic reticulum Ca(2+) pumps in association with head and neck squamous cell carcinoma.

ATP2A2 ATP2A3

3.91e-052218218295663
Pubmed

Phosphodiesterase 5 attenuates the vasodilatory response in renovascular hypertension.

GUCY2D PDE5A

3.91e-052218224260450
Pubmed

MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity.

CYBB ITGAM

3.91e-052218217654704
Pubmed

Localization of human cell cycle regulatory genes CDC25C to 5q31 and WEE1 to 11p15.3-11p15.1 by fluorescence in situ hybridization.

WEE1 CDC25C

3.91e-05221828432534
Pubmed

SPEG Controls Calcium Reuptake Into the Sarcoplasmic Reticulum Through Regulating SERCA2a by Its Second Kinase-Domain.

SPEG ATP2A2

3.91e-052218230566039
Pubmed

Uncoupling protein 2, but not uncoupling protein 1, is expressed in the female mouse reproductive tract.

UCP1 UCP2

3.91e-052218212941933
Pubmed

Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis.

UCP1 UCP2

3.91e-052218233579234
Pubmed

Dissection of the functional differences between sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) 1 and 2 isoforms and characterization of Darier disease (SERCA2) mutants by steady-state and transient kinetic analyses.

ATP2A1 ATP2A2

3.91e-052218212975374
Pubmed

Retinoid X receptor γ up-regulation is correlated with dedifferentiation of tumor cells and lymph node metastasis in papillary thyroid carcinoma.

RXRA RXRG

3.91e-052218221355951
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO1A MYO1C EPB41L3 CXXC1 SACS HSPA1L DDX39B VARS1 FLNA FLNC RANBP2 NSD2 PCDHGA5 SYNE1 PRDX4 SLC4A3 STT3B PRKDC PLCH1 ATP1A4 ATP2A1 ATP2A2 ATP2A3

4.19e-0514422182335575683
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

MYO1C USP9X EPB41L3 ZYX JAK1 DDX39B PTCD3 FLNA FLNC PRDX4 PPAT RIF1 PRKDC

5.05e-055512181334728620
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

EPPK1 USP9X CPSF2 DDX39B VARS1 FLNA RANBP2 RIF1 PRKDC ZMYM3

5.17e-053322181032786267
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

EPPK1 MYO1C USP9X EPB41L3 ITGAM ZYX FCGBP WASHC5 RRP12 OSBPL10 BOP1 TALDO1 HSPA1L VARS1 FLNA FLNC RANBP2 PRDX4 IGF2R ATIC PRKDC ATP2A2

5.44e-0513672182232687490
Pubmed

A human MAP kinase interactome.

EPB41L3 ZYX SYNJ2 MCM3AP USP53 FLNA FLNC RANBP2 SYNE1 RIF1 FHOD1 PRKDC

6.40e-054862181220936779
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

EPB41L3 WASHC5 VARS1 STK25 FLNA FLNC IGF2R SLITRK5

6.86e-05215218835973513
GeneFamilyATPases Ca2+ transporting

ATP2A1 ATP2A2 ATP2A3

4.35e-05914831209
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SPEG NOTCH3 FOXD1 FLNA VTN CCRL2 RFPL4A PDE5A ATP2A3

3.79e-081912181096ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SPEG NOTCH3 FOXD1 FLNA VTN CCRL2 RFPL4A PDE5A ATP2A3

4.39e-08194218103bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SPEG NOTCH3 FOXD1 FLNA VTN CCRL2 RFPL4A PDE5A ATP2A3

4.39e-0819421810fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG DHCR24 NOTCH3 STUM VTN KCNH3 BRINP2 SCUBE3 PDE5A

2.47e-071782189416f85e51f45ec7949451fd47611a84e33e87245
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAT2 DHRS4 PTPRM CSAD DDX39B PRDX4 NOB1 PPAT ATIC

5.33e-07195218944ac99e33b20a377009b8fef16142050a3e1da51
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO1A SPEG COL21A1 ALPK3 COL6A1 FLNA FLNC SYNE1 CCRL2

5.81e-071972189ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCelldroplet-Thymus-nan-21m-Myeloid-Plasma_cells_and_B_cells|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR FKBP11 CACNA1S B3GNT9 PRDX4 SLC4A3 CRYBA4 ASTN1

1.60e-06165218821a82a975f550080b6674750b06212205cd16742
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG DHCR24 NOTCH3 STUM VTN KCNH3 BRINP2 SCUBE3

2.70e-061772188dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellStriatum-Endothelial-MURAL|Striatum / BrainAtlas - Mouse McCarroll V32

MYO1C HSPA1L NOTCH3 FOXD1 VTN CCRL2 PDE5A ATP2A3

2.93e-0617921883d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)|Striatum / BrainAtlas - Mouse McCarroll V32

MYO1C HSPA1L NOTCH3 FOXD1 VTN CCRL2 PDE5A ATP2A3

2.93e-06179218899167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPOR ARHGEF6 NOTCH3 CFAP91 VTN CCRL2 ARHGAP9 PDE5A

3.74e-061852188b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 SIGLEC15 PTPRM DHCR24 COL6A1 WNT3 ANKH NEURL3

4.21e-061882188762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG COL21A1 NOTCH3 FLNA BRINP2 HES4 ASTN1 PDE5A

4.38e-06189218807208d32afca6f93207a2ac35b647b31a9f71b7c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG COL21A1 NOTCH3 FLNA BRINP2 HES4 ASTN1 PDE5A

4.38e-061892188032f169e8ede653117919bf97c17f92043320b3c
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 ARHGAP9 PDE5A

4.55e-061902188979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_E|PND01-03-samps / Age Group, Lineage, Cell class and subclass

UCP1 ARHGEF6 NOTCH3 VTN BRINP2 PDE5A ANKRD7

4.66e-06135218735928195cf34f055b353562c96f451aef2344d64
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG NOTCH3 FLNA STUM VTN BRINP2 ASTN1 PDE5A

4.73e-0619121885c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCellP07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 ARHGAP9 PDE5A

4.73e-0619121882ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE1A ISM1 NOTCH3 COL6A1 VTN PNMT PDE5A CSMD1

4.73e-061912188fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE1A ISM1 NOTCH3 COL6A1 VTN PNMT PDE5A CSMD1

4.92e-061922188dc4b4e16e6eb212e45fb70695afd1c7e91027407
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPEG GPR173 NOTCH3 FLNC STUM VTN PNMT PDE5A

4.92e-0619221882cc712186e37fb21a964c032765c36a8b4a852cf
ToppCellP28-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPEG ARHGEF6 NOTCH3 FLNA STUM VTN SCUBE3 CSMD1

4.92e-06192218887c7780cf72f4c204f2a5f6655309d47a23c08ae
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 ARHGAP9 PDE5A

4.92e-061922188063e119c4b58957643908f667e6cfd6f7517fd03
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG NOTCH3 FLNA STUM VTN BRINP2 ASTN1 PDE5A

4.92e-061922188eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADGRB1 ITGAM PTPRM DNAH5 FLNA VTN FCAMR SEC14L5

5.31e-061942188f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 IGF2R PDE5A

5.51e-0619521887a32a8535c29b819dacba901d0658280a2631c94
ToppCellPND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 IGF2R PDE5A

5.51e-0619521884a5d2f62aad5817d077177bf8b4ff0e46d3b8d97
ToppCellE18.5-Mesenchymal-Mesenchymal_structural|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ISM1 FKBP11 ZYX COL6A1 B3GNT9 IGF2R FHOD1 PEAK1

5.72e-06196218897e26622d9582b092c18ff5b7e957818f99d9631
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 ABCA1 PLD3 SIGLEC15 FCGBP WNT3 ANKH NEURL3

5.72e-061962188bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPEG SGCE NOTCH3 COL6A1 FLNA FLNC STUM PDE5A

5.72e-06196218892c5be6e43571730c7709046856f6c8ae341a4a1
ToppCell10x5'v1-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCA1 PLD3 EPB41L3 SIGLEC15 FCGBP WNT3 ANKH NEURL3

5.72e-061962188e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ISM1 FKBP11 ZYX COL6A1 B3GNT9 IGF2R FHOD1 PEAK1

5.72e-061962188f429f045ba45e24717963315832150b12a115bfa
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCA1 PLD3 EPB41L3 SIGLEC15 FCGBP WNT3 ANKH NEURL3

5.72e-0619621883bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 ABCA1 PLD3 SIGLEC15 FCGBP WNT3 ANKH NEURL3

5.72e-061962188072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG COL21A1 ALPK3 COL6A1 FLNA FLNC SYNE1 PDE5A

6.17e-061982188c12e7511628db819a52959bb68580e27c00c2e41
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPEG COL21A1 ALPK3 COL6A1 FLNA FLNC SYNE1 PDE5A

6.17e-06198218822e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CYBB EPPK1 ITGAM FBXW5 FLNA SYNE1 ARHGAP9 ATP2A3

6.40e-061992188a1635a52318be0423f8e4fc03d971c28cd22b57e
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 ABCA1 PLD3 SIGLEC15 COL6A1 WNT3 ANKH NEURL3

6.40e-061992188cbd423c31d75f6d2f5ae85d2241641fcbe630b81
ToppCell10x5'v1-week_17-19-Myeloid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 ABCA1 PLD3 SIGLEC15 COL6A1 WNT3 ANKH NEURL3

6.40e-061992188980b10b81ee9dc952e3be25bd294201ce5a4ca8b
ToppCellmedial-2-mesenchymal-Airway_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE1A SPEG COL21A1 NOTCH3 COL6A1 FLNC HES4 PDE5A

6.64e-06200218816b00eacbea4d75cf814803d3fc0b82c2b8c0a9c
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE1A SPEG COL21A1 NOTCH3 COL6A1 FLNC HES4 PDE5A

6.64e-062002188c1d9748aaae489d26e24602a5dcbe7f5fa9a5548
ToppCellmedial-mesenchymal-Airway_Smooth_Muscle-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PDE1A SPEG COL21A1 NOTCH3 COL6A1 FLNC HES4 PDE5A

6.64e-0620021886a5047018b12be3bc4b55a64d42e52e96c624003
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPEG SACS NOTCH3 STUM CPZ PDE5A ATIC

7.46e-06145218790ca38c02325c5c637c32efdef634b54cc3cd105
ToppCellPND01-03-samps-Mesenchymal-Pericyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ISM1 UCP1 ARHGEF6 NOTCH3 VTN BRINP2 PDE5A

1.02e-051522187fc9472bc19f997103da535b035105f01429cb08e
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

SPEG COL21A1 COL6A1 FLNC STUM GIPC3 PDE5A

1.42e-051602187d783d29150033e9181c0e30870070268fed3fd85
ToppCelldroplet-Pancreas-Exocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FKBP11 COL6A1 VTN PNMT PRDX4 CPB1 CDC25C

1.73e-051652187c17e00ec9dbe30fcded65a461231dbb13665ddac
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Vipr2_(central_amygdaloid_nucleus,_medial_division,_anterodorsal_part_(CeMAD))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYO1A SPINT1 DNAH5 CACNA1S TMPRSS9

1.79e-05662185c522722e99922caf4abe7103f1492ea96d3786a5
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Vipr2_(central_amygdaloid_nucleus,_medial_division,_anterodorsal_part_(CeMAD))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYO1A SPINT1 DNAH5 CACNA1S TMPRSS9

1.79e-05662185c6888ebcaba37486d9a12ad4d76669fb4e3c8fba
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Vipr2_(central_amygdaloid_nucleus,_medial_division,_anterodorsal_part_(CeMAD))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYO1A SPINT1 DNAH5 CACNA1S TMPRSS9

1.79e-056621856db3933fde0eee67dc5da85d7008c4fef9f684f5
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP6V1B1 AMACR SIGLEC15 PDF GRIN3A STUM PNMA6A

1.80e-0516621876d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCellBL-critical-LOC-Epithelial-Ionocyte|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP6V1B1 PDE1A AMACR STUM PCDHGA5 WNT3 SCUBE3

2.10e-051702187b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

ABCA1 KLHL35 SLC26A1 RXRA FCGBP VPS35L DNHD1

2.26e-051722187f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellClub-club-3|World / Class top

ATP6V1B1 FCGBP PROB1 CAPN5 LGSN SLITRK5 BRINP2

2.26e-05172218734fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

SPEG SACS COL21A1 COL6A1 STUM GIPC3 PDE5A

2.35e-051732187a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

KRI1 MELTF CSAD RANBP2 B3GNT9 SLC4A3 HES4

2.44e-0517421872274648b80dd74f3c948a779bba3391095964c34
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB ATP6V1B1 ACP2 UCP2 OSBPL10 CACNA1S RNASE12

2.44e-051742187dc4298c1d9359f7e37454e9451f889017227d5cf
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ABCA1 ACP2 ADGRB1 PLD3 FCGBP ANKH ATP1A4

2.82e-051782187e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TM6SF2 SACS SH3TC2 FLNC CCRL2 CPZ PLCH1

2.92e-051792187adf8b025032a03dbb58871a92025cd7efbeb22ff
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BDP1 CLSTN3 PATZ1 SPEG AP1G2 ARHGAP9 CPB1

2.92e-051792187db76edd368eeca05a2a5d407c3eb2f535ade0ce3
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG DNAH5 FLNA CFAP91 VTN PDE5A ATP2A3

3.13e-051812187c1b1e62440805800a3a600b1ddd79be1c9762598
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR ISM1 NOTCH3 CFAP91 VTN PDE5A SBK3

3.25e-051822187aba4c06d5d7618ac21b2695bca8e7a1346a91090
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR ISM1 NOTCH3 CFAP91 VTN PDE5A SBK3

3.25e-0518221879edaccf1154cec92ca9a28e9b1f9075cfd422bfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A NOTCH3 FLNA VTN SLC4A3 PDE5A ATP2A3

3.25e-051822187ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SPEG NOTCH3 FLNA VTN PDE5A ATP2A3

3.48e-05184218789ae8bf1a6c2d355d279d23a5e24a08d9ec2334e
ToppCellfacs-Lung-24m-Hematologic-myeloid|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYBB SPINT1 ITGAM ZYX TALDO1 FLNA ARHGAP9

3.48e-051842187c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ISM1 ARHGEF6 NOTCH3 VTN CCRL2 ARHGAP9 PDE5A

3.48e-05184218723c24ab5786af33d605bc445d06117b9da6c6331
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A SPEG NOTCH3 FLNA VTN PDE5A ATP2A3

3.48e-05184218734c84ac9a32eaf96f45b79485119cad65905817d
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A NOTCH3 FLNA VTN SLC4A3 PDE5A ATP2A3

3.48e-05184218794748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A NOTCH3 FLNA VTN SLC4A3 PDE5A ATP2A3

3.48e-051842187819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPOR ANKLE1 SLFN14 UCP2 FKBP8 TALDO1 CPB1

3.60e-051852187c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL6A1 FLNC VTN CPB1 CPZ BRINP2 ASTN1

3.73e-0518621877812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCellP15-Mesenchymal-developing_mesenchymal_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EPOR ARHGEF6 NOTCH3 VTN CCRL2 ARHGAP9 PDE5A

3.73e-051862187db9b67066fc003c7995ec205d15176bf40c97add
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-osteoclast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 MYO1C SIGLEC15 COL6A1 WNT3 ANKH NEURL3

3.73e-051862187c9dfcf7bba7e5ef97ad5d9b7084fba932c91ab68
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

ISM1 ZYX COL6A1 IGF2R FHOD1 PDE5A PEAK1

3.99e-0518821873f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAT2 DHRS4 PTPRM CSAD PRDX4 NOB1 PPAT

4.13e-051892187be09a116ce0ea9ddfa0974806c6f805438e44660
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG NOTCH3 FLNA HES4 ASTN1 PDE5A CSMD1

4.13e-0518921877fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG NOTCH3 FLNA HES4 ASTN1 PDE5A CSMD1

4.13e-05189218706b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 PDE5A

4.27e-0519021877fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 PDE5A

4.27e-0519021877e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 PDE5A

4.27e-0519021871004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR ISM1 ARHGEF6 NOTCH3 VTN CCRL2 PDE5A

4.27e-05190218710b02c62e72bfea9767e3e751011436925da823e
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ISM1 ARHGEF6 NOTCH3 VTN CCRL2 ARHGAP9 PDE5A

4.41e-051912187ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 MYO1C SIGLEC15 COL6A1 WNT3 ANKH NEURL3

4.41e-0519121874cebaf31d4f09f4ab273a819ad5cbff7d9a9b341
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A NOTCH3 FOXD1 FLNA VTN PDE5A ATP2A3

4.41e-051912187cb75e6c36dbe2e091e407d691c063ec7c4fd5f90
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A NOTCH3 FOXD1 FLNA VTN PDE5A ATP2A3

4.41e-051912187b2cffea7860dd590b505ee0ebd51aa1978cb5e64
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B2 USP9X PLD3 EPB41L3 UCP2 CASTOR2 ANKH

4.41e-051912187b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell10x5'v1-week_12-13-Myeloid_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATP6V1B2 MYO1C SIGLEC15 COL6A1 WNT3 ANKH NEURL3

4.41e-051912187be2fe2583bdcee0b35c43a347da9c4adb93e30e0
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 USP9X EPB41L3 ANKH PDE5A ATP2A2 ATP2A3

4.56e-0519221875b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG COL21A1 NOTCH3 FLNA HES4 ASTN1 CSMD1

4.56e-051922187bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPEG COL21A1 NOTCH3 FLNA HES4 ASTN1 CSMD1

4.56e-051922187b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1A NOTCH3 FOXD1 FLNA VTN PDE5A ATP2A3

4.56e-051922187e5117cdb8af220f60bd1410262078c0306667b4a
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

LEMD3 USP9X ATRN RANBP2 DDI2 IGF2R PRKDC

4.71e-051932187abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP6V1B2 EPB41L3 UCP2 CASTOR2 ANKH ATP2A2 ATP2A3

4.71e-05193218715c86e20b97b6983410b36d308cddff56d141c98
ToppCellP28-Mesenchymal-myocytic_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE1A SPEG NOTCH3 FLNA PNMT SCUBE3 CSMD1

4.87e-05194218783e45441c74b7f50b6725876b583229280179dc2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYBB ABCA1 EPB41L3 ITGAM USP53 RANBP2 ANKH

4.87e-051942187449ce4167d64c170d914e0250f739eabedcf915d
ToppCellproximal-3-Epithelial-Serous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FKBP11 FCGBP GPAT2 NEURL3 BRINP2 SV2C ATP2A3

5.03e-05195218724a6a566143b04e37ad002e4c55037a0460ac2ef
ToppCellproximal-Epithelial-Serous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FKBP11 FCGBP GPAT2 NEURL3 BRINP2 SV2C ATP2A3

5.03e-05195218706b73abc1f32543f2a51db52dc6424a2a398fe0f
ToppCellproximal-Epithelial-Serous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FKBP11 FCGBP GPAT2 NEURL3 BRINP2 SV2C ATP2A3

5.03e-051952187cb62f04f0e45bfb36eed2e7a3fc54d6d390b2ed1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 USP9X EPB41L3 RIF1 PDE5A ATP2A2 ATP2A3

5.03e-0519521873e519cffa6144a62b06124642a14c9ff39b76554
ToppCell356C-Fibroblasts-Fibroblast-K_(Pericytes)|356C / Donor, Lineage, Cell class and subclass (all cells)

SPEG COL21A1 NOTCH3 COL6A1 FLNC SCUBE3 PDE5A

5.19e-051962187a5cc4f76e1a3825aaccba9a686d7da6f7e4300ff
DrugAC1L1IIA

CYBB ATP6V1B1 ATP6V1B2 UCP1 UCP2 COL6A1 ATIC ATP2A1 ATP2A2 ATP2A3 YME1L1

7.70e-0717221511CID000004591
Drugorthovanadate

ATP6V1B1 ATP6V1B2 PDE1A ABCA1 MYO1C ACP2 PLD3 JAK1 ALPK3 KIF25 PDE5A PRKCI CDC25C ATP2A1 ATP2A2 ATP2A3 YME1L1

9.14e-0743521517CID000061672
DrugTEMPOL-H

CDKN1A ITGAM UCP2 PRKDC

1.55e-06102154ctd:C505333
DrugEUK-8

CYBB CDC25C ATP2A1 ATP2A2 ATP2A3

3.26e-06252155CID000171249
Drugpotassium

ATP6V1B1 MYO1A ACP2 ISM1 METAP1D CHM SACS KCNJ14 PKD1 SLC9A7 TALDO1 ATRN CACNA1S NPR2 SYNE1 KCNH3 SV2C PRKCI ATIC PLCH1 ATP1A4 ATP2A1 ATP2A2 ATP2A3 YME1L1

1.07e-05100821525CID000000813
Drugketene

PATZ1 SYNE1 ARHGAP9 INTS5

1.67e-05172154CID000010038
DrugOxalamine citrate salt [1949-20-8]; Up 200; 9.2uM; PC3; HT_HG-U133A

CYBB EPOR CLSTN3 UCP2 MCM3AP SLC9A7 STUM NSD2 DDX51 BRINP2

1.82e-05196215106624_UP
DrugSaquinavir mesylate [149845-06-7]; Down 200; 5.2uM; PC3; HT_HG-U133A

EPPK1 PATZ1 TNFRSF6B PGGT1B RUSC2 SYNJ2 VPS35L FKBP8 COL6A1 NPR2

1.90e-05197215105770_DN
DrugHX600

ITGAM RXRA RXRG SYNE1

2.13e-05182154CID000128016
DiseaseBrody myopathy (implicated_via_orthology)

ATP2A1 ATP2A2 ATP2A3

3.35e-0732063DOID:0050692 (implicated_via_orthology)
DiseaseMetastatic melanoma

ALPK3 GUCY2D PRKCI PRKDC PEAK1

3.78e-05542065C0278883
DiseaseMental Retardation, X-Linked

RAB40AL ARHGEF6 ZNF41 ZMYM3

4.78e-05292064C1136249
DiseaseMental Retardation, X-Linked 1

USP9X SLC9A7 ARHGEF6 ZNF41

7.12e-05322064C2931498
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

1.45e-0432062DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

1.45e-0432062DOID:0111190 (implicated_via_orthology)
Diseasesystemic lupus erythematosus (implicated_via_orthology)

CYBB CDKN1A RXRA JAK1

2.30e-04432064DOID:9074 (implicated_via_orthology)
Diseaseglucose homeostasis measurement, acute insulin response measurement

PTPRM ATP2A2 ATP2A3

2.53e-04182063EFO_0006831, EFO_0006896
Diseaselysozyme-like protein 2 measurement

SLFN14 VTN

4.78e-0452062EFO_0801779
Diseaseresponse to bevacizumab, Proteinuria

JAK1 DNAH5

4.78e-0452062EFO_0005943, HP_0000093
Diseasefollicular lymphoma (implicated_via_orthology)

ATP6V1B1 ATP6V1B2

4.78e-0452062DOID:0050873 (implicated_via_orthology)
Diseasecerebellum cortex volume change measurement, age at assessment

PTPRM CSMD1 PLCH1

7.74e-04262063EFO_0008007, EFO_0021497
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

RNF123 CELSR3

9.95e-0472062EFO_0020797
Diseasepolycystic liver disease (implicated_via_orthology)

UCP2 PKD1

9.95e-0472062DOID:0050770 (implicated_via_orthology)
Diseaserho GTPase-activating protein 30 measurement

CYP4V2 VTN

9.95e-0472062EFO_0802012
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH3 HES4

9.95e-0472062DOID:3620 (implicated_via_orthology)
Diseasepremature menopause (biomarker_via_orthology)

ABCA1 ACAT2

1.32e-0382062DOID:10787 (biomarker_via_orthology)
Diseaserenal tubular acidosis (implicated_via_orthology)

ATP6V1B1 ATP6V1B2

1.32e-0382062DOID:14219 (implicated_via_orthology)
Diseaseresponse to lamotrigine

GRIN3A CSMD1

1.69e-0392062EFO_0007661
DiseaseJT interval

CDKN1A CABLES2 COL21A1 ALPK3 RNASE12 SLC4A3 SBK3

1.86e-032482067EFO_0007885
Diseaseheart failure

CDKN1A MYO1C PKD1 FLNC PNMT ACAD10

1.96e-031852066EFO_0003144
DiseaseDisproportionate short stature

DHCR24 FLNA NPR2 ANKH

2.10e-03772064C0878659
Diseaseheart disease (implicated_via_orthology)

ATP2A1 ATP2A2 ATP2A3

2.36e-03382063DOID:114 (implicated_via_orthology)
Diseasepregnenetriol sulfate measurement

PUDP UGT1A4

2.56e-03112062EFO_0800586
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

LEMD3 SYNE1

3.06e-03122062DOID:11726 (implicated_via_orthology)
Diseasepersulfide dioxygenase ETHE1, mitochondrial measurement

CYP4V2 VTN

3.06e-03122062EFO_0008258
Diseasepregnenetriol disulfate measurement

PUDP UGT1A4

3.60e-03132062EFO_0800587
Diseasetransmembrane protein 87B measurement

CYP4V2 VTN

3.60e-03132062EFO_0802158
DiseaseX-19141 measurement

UGT2B17 UGT2B11

3.60e-03132062EFO_0800799
Diseaseleft ventricular systolic function measurement

MYO1C ALPK3 FLNC

3.60e-03442063EFO_0008206
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD1 FLNC

4.18e-03142062DOID:898 (implicated_via_orthology)
Diseaseperiodontitis

ABCA1 EPPK1 MCM3AP OSBPL10 IGF2R CSMD1

4.92e-032232066EFO_0000649
Diseaseneutrophil collagenase measurement

HSPA1L VTN

5.46e-03162062EFO_0008248
Diseasetotal lipids in LDL measurement

ABCA1 TM6SF2 IGF2R

5.76e-03522063EFO_0022308
Diseaseessential hypertension (is_implicated_in)

NPR2 ATP2A2

6.89e-03182062DOID:10825 (is_implicated_in)
Diseaseinfant grey matter volume measurement

VPS35L SEC14L5

6.89e-03182062EFO_0008368

Protein segments in the cluster

PeptideGeneStartEntry
DVFGNATERCPLIAA

URAD

16

A6NGE7
PAVCLVAAAVEDSVL

BOP1

466

Q14137
PLSICSFRVGAEENL

AMER3

456

Q8N944
VCVTFRELSAEFGPG

ALKBH4

266

Q9NXW9
EDAEATVVLVGCVPF

SLC4A3

511

P48751
DLPSFEVGIRALCEV

BDP1

566

A6H8Y1
LFGPVDSEQLSRDCD

CDKN1A

21

P38936
VPSLCSAVFVIGVLD

CCRL2

41

O00421
GCATLQVEIFDPDDL

ARHGEF6

76

Q15052
AAALRTGCIPDVQAD

ANKLE1

411

Q8NAG6
SLALFPGIRLETCDE

CLSTN3

261

Q9BQT9
FECPAAFELVGERVI

CSMD1

551

Q96PZ7
PVVVAFSRAADCAVD

NKAPP1

76

Q8N9T2
VLASQPDLECGFSRD

CPSF2

326

Q9P2I0
VIFEDCAVPVANRIG

ACAD8

246

Q9UKU7
GVESFDEVLRLCDPS

ADGRB1

116

O14514
LLRAIVDCGFEHPSE

DDX39B

56

Q13838
IFDGTDACVTPVLTF

AMACR

286

Q9UHK6
LVVGPTDDGCFLELR

GTPBP2

441

Q9BX10
CPQFDAITELLTGRE

ABCA1

1991

O95477
FDECGIVAQISEPLA

CASTOR2

276

A6NHX0
FCLSPEVLSGFISRE

ALPK3

1561

Q96L96
CASGILLAAERFAPT

AP1G2

401

O75843
VLDLCEDSSVIGTPF

ACAD10

346

Q6JQN1
AEAFGIAPTEILFCT

GIPC3

66

Q8TF64
PVDLRFVSSELEGAC

NPR2

61

P20594
GICEDPRLFVDGISS

CAPN5

56

O15484
VEIPGSVLDDLCSRF

DCP2

6

Q8IU60
VLRPECLAGALADFT

DNHD1

4046

Q96M86
RLGEPEDCAGIVSFL

DHRS4

241

Q9BTZ2
ADSIDGICARFPSLL

DCUN1D3

156

Q8IWE4
EVVCIFLTAALGLPE

ATP2A1

771

O14983
PVRCGQFDGLVELAT

ATP2A3

401

Q93084
VLLDSFGPVRDCSKD

ASTN1

601

O14525
GLVELESCLPDFVTQ

CFAP91

401

Q7Z4T9
ELCSPDIAVAIEFVR

CCDC60

506

Q8IWA6
EPGTFAVRVIELCSS

CHM

481

P24386
VFFDVCADGEPLGRI

RANBP2

3066

P49792
CDPTVGVDFFSRLLE

RAB39A

41

Q14964
ERLGVTFFEVSPLCN

RAB40A

146

Q8WXH6
ERLGVTFFEVSPLCN

RAB40B

146

Q12829
ERLGVTFFEVSPLCN

RAB40AL

146

P0C0E4
AVCDGVLGVFALDDP

ERAS

111

Q7Z444
SLCAAVNRALDEGIP

C9orf64

101

Q5T6V5
LTLSEICEFISGRFP

FOXD1

146

Q16676
LLAREGIDSECGPFI

JAK1

721

P23458
ISEDCLPGTVIALFS

PCDHGA5

356

Q9Y5G8
EVLQLPLFEAASRGC

KCNH3

576

Q9ULD8
IRCVGFGPEEELTNI

LEMD3

591

Q9Y2U8
GDRTSSCPVIFILDE

ORC4

146

O43929
LAEEAAPEVAGLSCL

FBXO21

16

O94952
CEAVLVESIPEGLDF

PLD3

81

Q8IV08
VELASAFSLPICEGL

PTCD3

631

Q96EY7
FEPSISFEGLCNEVR

PRKCI

41

P41743
VPEDVRVGCLTTDFA

NOB1

226

Q9ULX3
GPESDFCLKVEAAVL

IL17RD

596

Q8NFM7
EAIAACRAGAPFSVI

METAP1D

216

Q6UB28
ACPGATEAEARAALV

GLTPD2

251

A6NH11
AACRPAELLAEEAGI

GUCY2D

131

Q02846
ECLRPGVVSDSTFLA

MYO1A

456

Q9UBC5
CLVFEDAPNGVEAAL

PUDP

171

Q08623
VAVFCSLRGLQEVPE

LRRC3

46

Q9BY71
LLPCEAEAAAAAAAV

ATRN

76

O75882
CVELNRSAFLEPEGL

MCM3AP

931

O60318
PCRIFDLGSDNEEVV

FBXW5

276

Q969U6
GNTEISLEACLFPDV

OR51J1

91

Q9H342
PVSCLITFAEALEVG

PDE1A

196

P54750
VPCLTVADFVRDSLA

PEAK1

1466

Q9H792
ALTHVSEDCFPLLDG

PDE5A

831

O76074
NGDTRVGLFAVCDIP

NSD2

1156

O96028
VGLFAVCDIPAGTEL

NSD2

1161

O96028
GCIVDKPAEFTIDAR

FLNC

681

Q14315
DGLDCASEVPALLAR

NOTCH3

1496

Q9UM47
TIAALGADCIPIVFA

LACC1

276

Q8IV20
RTVVPCDFGLSTEEI

KRI1

526

Q8N9T8
ELCADLFRGTLEPVE

HSPA1L

306

P34931
TAADGPCALRELSVD

AMH

456

P03971
ELAVRLGFGPCAEEQ

PLA2G4B

251

P0C869
EPDGEGLLCRFCSVV

RFPL4A

41

A6NLU0
LDSRLVTFPEGCESV

PDF

161

Q9HBH1
IIIVFHCEFSSERGP

CDC25C

371

P30307
GVRSVTEECPAAVAA

KCNJ14

151

Q9UNX9
VFTREVDDEGLCPAG

GRIN3A

526

Q8TCU5
CDVLLRVGDESFPAH

PATZ1

41

Q9HBE1
PADTEVIVALAVCGS

ACP2

376

P11117
VFGVLEDCSPTLLAD

PCTP

56

Q9UKL6
EIIFSPECTEAEGRH

PRICKLE3

256

O43900
FPLKTDESGACVIDR

KCTD18

46

Q6PI47
QFVSSVPRCDLVDLG

FAM189A2

31

Q15884
PLVVEDFVKDSGACF

GATD1

166

Q8NB37
VVCIFLTAALGFPEA

ATP2A2

771

P16615
TLVVRACDLATDPGF

CDHR2

891

Q9BYE9
CPLVRDVFELTGDFC

CXXC1

566

Q9P0U4
FVVRLSQLSPDDIGC

FCAMR

136

Q8WWV6
PELVFTLGDCDVIQA

FKBP8

141

Q14318
AVCRAEAGLETESPV

FKBP11

21

Q9NYL4
FSVIGPTDDRSCAVI

KLRF2

161

D3W0D1
TVLVVAAARPGCEFE

CPZ

11

Q66K79
DILFPLDSVIGTELC

C5orf60

16

A6NFR6
CGPIDLLFVLDSSES

COL6A1

611

P12109
AAPEICRTVSGDLAA

CACNA1S

1566

Q13698
AAVIPALLESAACGF

DDX51

226

Q8N8A6
DAGFVLSADRCVPLN

FCGBP

3191

Q9Y6R7
AELTIEICSEAGLPA

FLNA

1191

P21333
GDPDLVLRCIVSGFF

DHX35

601

Q9H5Z1
ELVLADGSFVRCTPS

DHCR24

191

Q15392
PAALGAFSDVLVRCE

F8A1;

256

P23610
LLPVFLSEAVGACAV

GPAT2

546

Q6NUI2
LFRAVPECQLSGGDI

CARD8

101

Q9Y2G2
CRTAPTDLVFILDGS

COL21A1

31

Q96P44
IIGVDFAFAELCVVP

ANKH

356

Q9HCJ1
DCATILLNFGADPDL

ANKRD7

106

Q92527
PLFARSVSEDCEVAG

CYP4V2

396

Q6ZWL3
RHEFTAECPSVLELG

CRYBA4

26

P53673
AECPSVLELGFETVR

CRYBA4

31

P53673
LFLGLAEACTPREVA

EDDM13

16

A0A1B0GTR0
GAFDPLEAIADVCQR

CSAD

251

Q9Y600
LADGIRSAVCFPFVL

GPR173

66

Q9NS66
VNRFLAGCEGVPADV

HES4

121

Q9HCC6
RIGVFLCGPEALAET

CYBB

531

P04839
LLAARGPEELLCFTE

EPOR

41

P19235
RALCELESGIPAAES

DDI2

31

Q5TDH0
DLVPEFVHSEGLSCL

FHOD1

151

Q9Y613
DSPFAEVTASGCRVL

CELSR3

2111

Q9NYQ7
EPFCALESATGAVAE

HELZ2

1946

Q9BYK8
TEGFVLVTCDDLRPD

RNASE12

126

Q5GAN4
AEVRAEETTASCGLP

SCUBE3

556

Q8IX30
DREVIPDFLGGESVC

SEC14L5

466

O43304
VFDPVCSRVALGDLG

SBK3

171

P0C264
FIDVFGCQLPLTVEA

SACS

1621

Q9NZJ4
ELGCLRAIVLFNPDS

RXRA

366

P19793
CPGIEDTFRTAATEV

ISM1

261

B1AKI9
FTELLPRCGEVESVG

IPO13

841

O94829
GFLLPESQIRATCEE

CPB1

386

P15086
LEFLEDAVGCAPAQR

CABLES2

131

Q9BTV7
DDIVSGRLPCSFVTL

EPB41L3

211

Q9Y2J2
VALTGVCVFFIRTDP

DNAH5

121

Q8TE73
ARVICDTFTVTGEPL

LGSN

166

Q5TDP6
LSCSFDVVSPVAGLR

PKD1

811

P98161
DRCLPFLITIDGESS

PTPRM

1226

P28827
LITFLCDRDAGVGFP

IGF2R

726

P11717
LRALQLEDGSFCAVP

PGGT1B

151

P53609
VVEGAEACPASEEAL

RUSC2

1321

Q8N2Y8
RPDCFLEVADEATGA

VARS1

1131

P26640
SCEFTGDILRTPVSE

ATP6V1B2

111

P21281
CEFTGDILRTPVSED

ATP6V1B1

106

P15313
ECPSAEVRGAFAKLI

USP9X

2106

Q93008
EPDGEGLLCRFCSVV

RFPL4AL1

41

F8VTS6
DTPGHVDFTLEVERC

GFM2

141

Q969S9
LERTVVFGLSPECDQ

SLFN14

871

P0C7P3
EVSAEAGDAAVLPCT

SIGLEC15

51

Q6ZMC9
VVGFVLPSAETDLCI

SV2C

171

Q496J9
ERPILQVDSCVFAGE

GTF3C6

51

Q969F1
TFVCPTEIIAFGDRL

PRDX4

121

Q13162
EAFREAGIQPSLLCV

MELTF

41

P08582
IGPDVSLENLAAETC

SPATA5L1

671

Q9BVQ7
LFVATALLPEETETC

SYNE1

6401

Q8NF91
CLLFEAGTVATLAPE

SYNJ2

31

O15056
GPVFLAGEALECVVT

RGP1

11

Q92546
SLPSGIVNFREEICD

RIF1

1826

Q5UIP0
LLALCVTDPETGLAF

EPPK1

451

P58107
VGSSPLEARACFLAI

SH3TC2

626

Q8TF17
EFSLFGIPLVGADIC

SI

621

P14410
VAEAAASLLAICPFP

INTS5

621

Q6P9B9
LVESVCPDAAGAELA

INTS5

816

Q6P9B9
LRGCPQEDSDIAFLI

ITGAM

141

P11215
AESQSAVFGDVCPLL

KIF25

36

Q9UIL4
AVFGDVCPLLTSLLD

KIF25

41

Q9UIL4
DVFSALEEPAVCRGL

OVCA2

81

Q8WZ82
FECVEVALEEGAAPA

PROB1

186

E7EW31
VAAEFLFVLCSESVP

RIC8A

391

Q9NPQ8
TAGATPEERVICFVE

OSBPL10

446

Q9BXB5
VGADVPFSSCLREVE

SGCE

226

O43556
LENAFSLAEESCPGI

STK25

386

O00506
LVVALAPCADEAAIS

RRP12

756

Q5JTH9
VVFVPRCSGEEFLGL

PNMA6A

91

P0CW24
CRPEVAESLENFLGL

BRINP2

491

Q9C0B6
RLAGACAQVELFPID

B3GNT9

301

Q6UX72
CAQVELFPIDDVFLG

B3GNT9

306

Q6UX72
GAPERILEFCSTFLL

ATP1A4

516

Q13733
SGAIDAFCQPELDSI

USP53

1011

Q70EK8
APLPADALVSAFCLE

PNMT

171

P11086
GIAACLADVITFPLD

UCP1

21

P25874
GTAACIADLITFPLD

UCP2

21

P55851
FALALTVVCAAGAEP

WEE1

501

P30291
ETPGTVLEVLICFFT

ZDHHC9

221

Q9Y397
FTPVDESVTFIGRLC

WASHC5

811

Q12768
EFASCRLEAVPLEFG

VPS35L

16

Q7Z3J2
SIADDIFPLISCVGA

XKRY

6

O14609
PLTDSILCDGLTDAF

ACAT2

141

Q9BWD1
ACQLTEFLIEPSLDG

RLF

411

Q13129
LFECLVAGPTDVEVD

SPEG

986

Q15772
SALVGDVVCETPFRL

SLITRK5

256

O94991
TVVIDCAPLLFLDAA

SLC26A1

611

Q9H2B4
CFRAVLSVELDPVEG

RNF123

281

Q5XPI4
IRDVCVFLAPTFSGL

STT3B

166

Q8TCJ2
VSAFTVLCGARTDLP

STUM

71

Q69YW2
PDRGEDAIAACFLIN

SPINT1

106

O43278
LDIISRSEGNPVAFC

PPAT

266

Q06203
LVCEEPSGRFFLAGI

TMPRSS9

391

Q7Z410
CTTIDDSLAIFGPVL

WNT3

91

P56703
SELGCLRAIVLFNPD

RXRG

366

P48443
EGDTVPSFLRLCIAA

ARHGAP9

551

Q9BRR9
GDFVALSDVCDVPTA

ATIC

316

P31939
DIVFADAVFPCGELL

UGT2B11

146

O75310
VRGPLFLCEDSELES

SNX19

361

Q92543
IFPLEGATFLCPADV

MRM2

116

Q9UI43
LEDVIADPTLCFNSG

PLCH1

1341

Q4KWH8
VLPEGCALTGDLVRF

NEURL3

111

Q96EH8
GIVDPVDSTLRDFCG

PRKDC

1016

P78527
APCVIFIDELDSVGG

YME1L1

431

Q96TA2
SIADDIFPLISCVGA

XKRY2

6

A2RUG3
ERFDQPIGEDSLCSI

ZNF41

161

P51814
EPVEELALSHCGRFL

WDR55

296

Q9H6Y2
VVCARPLEGTSFIVD

ZYX

471

Q15942
CFQISPAEETLELGR

TP53TG3

61

Q9ULZ0
VACAEAGVTLISPFV

TALDO1

176

P37837
FTLFRGLVVLDCPTD

TM6SF2

231

Q9BZW4
DCLFFGAIISATDPV

SLC9A7

251

Q96T83
GPVCFANDRGDLLVT

WDR87

611

Q6ZQQ6
GIEGPIDAAFTRINC

VTN

201

P04004
AEGLLEDCDLFGPAR

ZMYM3

961

Q14202
FDVLLADAVNPCGEL

UGT2B17

146

O75795
CAPEAVIDASGISVD

ZFY

181

P08048
PGAEECERAVIDFVA

TNFRSF6B

206

O95407
PSIIFIDEVDSLCGS

VPS4A

221

Q9UN37
FDVVLTDPVNLCGAV

UGT1A4

146

P22310
VAAAFSLAPLAERCG

KLHL35

161

Q6PF15
EECLRPGEATDLTFL

MYO1C

496

O00159