Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

ATP7B SLC16A9 SLC26A4 CLDN4 ANO10 ATP13A2 RYR1 RHCE SLC7A8 SLC6A7 SLC2A10 SLC17A5 SEC61A2 CACNG6 MFSD14B SLC41A3 SLC2A6 ABCC8 SLC27A1 KCNMB1 CACNA1H SEC61A1 SLC7A10 ATP2B4 SLC27A4

1.13e-08118011525GO:0022857
GeneOntologyMolecularFunctiontransporter activity

ATP7B SLC16A9 SLC26A4 APOA1 CLDN4 ANO10 ATP13A2 RYR1 RHCE SLC7A8 SLC6A7 SLC2A10 SLC17A5 SEC61A2 CACNG6 MFSD14B SLC41A3 SLC2A6 ABCC8 SLC27A1 KCNMB1 CACNA1H SEC61A1 SLC7A10 ATP2B4 SLC27A4

1.48e-08128911526GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ATP7B SLC26A4 CLDN4 ANO10 RYR1 RHCE SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

7.14e-0675811516GO:0015318
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC2A6 SLC27A1 SLC7A10 SLC27A4

7.62e-0629311510GO:0008514
GeneOntologyMolecularFunctionATP-dependent activity

MYH1 ATP7B COQ8B NLRP1 ATP13A2 DDX11 DNAH12 ABCC8 SLC27A1 MCM9 HLTF KIF28P ATP2B4 SLC27A4

1.19e-0561411514GO:0140657
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP7B SLC26A4 CLDN4 ANO10 ATP13A2 RYR1 SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

1.25e-0579311516GO:0015075
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC17A5 SLC27A1 SLC7A10 SLC27A4

2.67e-052071158GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC17A5 SLC27A1 SLC7A10 SLC27A4

2.76e-052081158GO:0005342
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP7B ANO10 ATP13A2 RYR1 SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

2.83e-0566411514GO:0008324
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP7B SLC26A4 ATP13A2 SLC6A7 SLC2A10 SLC17A5 SLC41A3 ABCC8 ATP2B4

6.20e-053011159GO:0022853
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP7B RYR1 RHCE SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

6.61e-0562711513GO:0022890
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP7B SLC16A9 SLC26A4 ATP13A2 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC41A3 ABCC8 ATP2B4

9.82e-0547711511GO:0022804
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor

MTHFD1 PYCR1 PYCR2

1.43e-04181153GO:0016646
GeneOntologyMolecularFunctionoleoyl-CoA ligase activity

SLC27A1 SLC27A4

1.96e-0441152GO:0090434
GeneOntologyMolecularFunctionpyrroline-5-carboxylate reductase activity

PYCR1 PYCR2

1.96e-0441152GO:0004735
GeneOntologyMolecularFunctionATP hydrolysis activity

ATP7B COQ8B NLRP1 ATP13A2 DDX11 DNAH12 ABCC8 MCM9 KIF28P ATP2B4

2.36e-0444111510GO:0016887
GeneOntologyMolecularFunctionpheromone binding

OBP2B OBP2A

3.25e-0451152GO:0005550
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ATP7B COQ8B NLRP1 NUDT9 ATP13A2 ARF6 DDX11 ARL4C DNAH12 ABCC8 MCM9 HLTF KIF28P ATP2B4

3.37e-0484011514GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ATP7B COQ8B NLRP1 NUDT9 ATP13A2 ARF6 DDX11 ARL4C DNAH12 ABCC8 MCM9 HLTF KIF28P ATP2B4

3.37e-0484011514GO:0016818
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

ATP7B RYR1 SLC6A7 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

3.59e-0446511510GO:0046873
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP7B ATP13A2 ABCC8 ATP2B4

4.50e-04621154GO:0019829
GeneOntologyMolecularFunctionoleate transmembrane transporter activity

SLC27A1 SLC27A4

4.86e-0461152GO:1901480
GeneOntologyMolecularFunctionCoA-ligase activity

DIP2A SLC27A1 SLC27A4

4.92e-04271153GO:0016405
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH group of donors

MTHFD1 PYCR1 PYCR2

6.75e-04301153GO:0016645
GeneOntologyMolecularFunctionacid-thiol ligase activity

DIP2A SLC27A1 SLC27A4

7.44e-04311153GO:0016878
GeneOntologyMolecularFunctioncarbohydrate:proton symporter activity

SLC2A10 SLC17A5

9.00e-0481152GO:0005351
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A10 SLC2A6

9.00e-0481152GO:0033300
GeneOntologyMolecularFunctionpyrophosphatase activity

ATP7B COQ8B NLRP1 NUDT9 ATP13A2 ARF6 DDX11 ARL4C DNAH12 ABCC8 MCM9 KIF28P ATP2B4

1.09e-0383911513GO:0016462
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP7B ATP13A2 ATP2B4

1.16e-03361153GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP7B ATP13A2 ATP2B4

1.16e-03361153GO:0015662
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC2A10 SLC2A6 SLC27A1

1.16e-03361153GO:0090482
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC16A9 SLC7A8 SLC6A7 SLC7A10

1.35e-03831154GO:0015101
GeneOntologyMolecularFunctionvery long-chain fatty acid-CoA ligase activity

SLC27A1 SLC27A4

1.44e-03101152GO:0031957
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC41A3

1.64e-032961157GO:0015291
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

DIP2A SLC27A1 SLC27A4

1.69e-03411153GO:0016877
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC7A8 SLC6A7 SLC7A10

1.69e-03411153GO:0015175
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ATP7B COQ8B NLRP1 ATP13A2 ARF6 DDX11 ARL4C DNAH12 ABCC8 MCM9 KIF28P ATP2B4

1.71e-0377511512GO:0017111
GeneOntologyMolecularFunctionarachidonate-CoA ligase activity

SLC27A1 SLC27A4

1.75e-03111152GO:0047676
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A10 SLC17A5 SLC2A6

1.81e-03421153GO:0015144
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

RYR1 CACNG6 CACNA1H SEC61A1 ATP2B4

1.82e-031511155GO:0015085
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

RYR1 CACNG6 CACNA1H

2.36e-03461153GO:0005245
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

IREB2 DDX11 METTL17

2.51e-03471153GO:0051539
GeneOntologyMolecularFunctionlong-chain fatty acid-CoA ligase activity

SLC27A1 SLC27A4

3.29e-03151152GO:0004467
GeneOntologyMolecularFunctionchannel activity

CLDN4 ANO10 RYR1 RHCE CACNG6 ABCC8 KCNMB1 CACNA1H SEC61A1

3.36e-035251159GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CLDN4 ANO10 RYR1 RHCE CACNG6 ABCC8 KCNMB1 CACNA1H SEC61A1

3.40e-035261159GO:0022803
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP7B ATP13A2 ABCC8 ATP2B4

3.65e-031091154GO:0042626
GeneOntologyMolecularFunctionmonoatomic cation channel activity

ANO10 RYR1 CACNG6 ABCC8 KCNMB1 CACNA1H SEC61A1

3.73e-033431157GO:0005261
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC2A10 SLC17A5

4.23e-03171152GO:0005402
GeneOntologyMolecularFunctionlong-chain fatty acid transmembrane transporter activity

SLC27A1 SLC27A4

4.74e-03181152GO:0005324
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CLDN4 ANO10 RYR1 CACNG6 ABCC8 KCNMB1 CACNA1H SEC61A1

5.10e-034591158GO:0005216
GeneOntologyBiologicalProcessheme metabolic process

BDH2 TMEM14C IREB2 TMEM14DP TMEM14B ALAS2

5.76e-07541166GO:0042168
GeneOntologyBiologicalProcesspigment metabolic process

BDH2 TMEM14C IREB2 TMEM14DP TYR TMEM14B ALAS2

1.01e-06941167GO:0042440
GeneOntologyBiologicalProcessheme biosynthetic process

TMEM14C IREB2 TMEM14DP TMEM14B ALAS2

1.26e-06341165GO:0006783
GeneOntologyBiologicalProcessporphyrin-containing compound metabolic process

BDH2 TMEM14C IREB2 TMEM14DP TMEM14B ALAS2

1.45e-06631166GO:0006778
GeneOntologyBiologicalProcesspigment biosynthetic process

TMEM14C IREB2 TMEM14DP TYR TMEM14B ALAS2

1.45e-06631166GO:0046148
GeneOntologyBiologicalProcessporphyrin-containing compound biosynthetic process

TMEM14C IREB2 TMEM14DP TMEM14B ALAS2

2.55e-06391165GO:0006779
GeneOntologyBiologicalProcesstetrapyrrole biosynthetic process

TMEM14C IREB2 TMEM14DP TMEM14B ALAS2

2.55e-06391165GO:0033014
GeneOntologyBiologicalProcesstetrapyrrole metabolic process

BDH2 TMEM14C IREB2 TMEM14DP TMEM14B ALAS2

3.48e-06731166GO:0033013
GeneOntologyBiologicalProcessregulation of heme biosynthetic process

TMEM14C TMEM14DP TMEM14B

1.42e-0591163GO:0070453
GeneOntologyBiologicalProcessregulation of tetrapyrrole biosynthetic process

TMEM14C TMEM14DP TMEM14B

1.42e-0591163GO:1901463
GeneOntologyBiologicalProcessregulation of tetrapyrrole metabolic process

TMEM14C TMEM14DP TMEM14B

2.02e-05101163GO:1901401
GeneOntologyBiologicalProcessmedium-chain fatty acid transport

SLC27A1 SLC27A4

3.14e-0521162GO:0001579
GeneOntologyBiologicalProcessorganic anion transport

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC2A6 ABCC8 SLC27A1 CD47 SLC7A10 SLC27A4

3.38e-0551511612GO:0015711
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ATP7B SLC26A4 STIMATE CLDN4 ANO10 RYR1 RHCE SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

5.37e-05101711617GO:0098660
GeneOntologyBiologicalProcessmyeloid cell homeostasis

TMEM14C IREB2 TMEM14DP ACVR1B RHCE MTHFD1 TMEM14B ALAS2

6.45e-052401168GO:0002262
GeneOntologyBiologicalProcessoxoacid metabolic process

MPO ACADVL OBP2A BDH2 IREB2 GNMT LDHC TYR MTHFD1 SLC2A6 SLC27A1 PYCR1 ACOT2 PYCR2 ALDH6A1 ATP2B4 SLC27A4

8.72e-05105811617GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

MPO ACADVL OBP2A BDH2 IREB2 GNMT LDHC TYR MTHFD1 SLC2A6 SLC27A1 PYCR1 ACOT2 PYCR2 ALDH6A1 ATP2B4 SLC27A4

9.34e-05106411617GO:0006082
GeneOntologyBiologicalProcesserythrocyte homeostasis

TMEM14C IREB2 TMEM14DP ACVR1B RHCE TMEM14B ALAS2

1.01e-041901167GO:0034101
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC7A8 SLC2A10 SLC27A1 ATP2B4 SLC27A4

1.32e-04871165GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLC7A8 SLC2A10 SLC27A1 ATP2B4 SLC27A4

1.39e-04881165GO:0010232
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC7A8 SLC2A10 SMTNL1 ADRA1B ABCC8 SLC27A1 KCNMB1 ATP2B4 SLC27A4

1.43e-043441169GO:0003018
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ATP7B SLC26A4 STIMATE CLDN4 ANO10 ATP13A2 RYR1 SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

1.64e-04111511617GO:0034220
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

ACADVL OBP2A BDH2 IREB2 GNMT LDHC TYR MTHFD1 SLC2A6 SLC27A1 PYCR1 ACOT2 PYCR2 ALDH6A1 ATP2B4 SLC27A4

2.22e-04103511616GO:0019752
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATP7B STIMATE ANO10 ATP13A2 RYR1 SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

2.59e-0494211615GO:0098655
GeneOntologyBiologicalProcessvitamin transport

APOA1 SLC2A10 SLC2A6 SLC27A1

2.78e-04561164GO:0051180
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC16A9 SLC7A8 SLC6A7 SLC17A5 SLC27A1 SLC7A10

3.22e-041631166GO:1905039
GeneOntologyBiologicalProcessimport across plasma membrane

SLC7A8 SLC6A7 SLC2A10 ABCC8 SLC27A1 CACNA1H ATP2B4

3.26e-042301167GO:0098739
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC16A9 SLC7A8 SLC6A7 SLC17A5 SLC27A1 SLC7A10

3.67e-041671166GO:1903825
GeneOntologyBiologicalProcesssmall molecule biosynthetic process

MPO ACADVL OBP2A COQ8B APOA1 GNMT LDHC MTHFD1 PYCR1 CACNA1H PYCR2 ATP2B4

4.28e-0467611612GO:0044283
GeneOntologyBiologicalProcessL-proline biosynthetic process

PYCR1 PYCR2

4.63e-0461162GO:0055129
GeneOntologyBiologicalProcesslipid transport across blood-brain barrier

SLC27A1 SLC27A4

4.63e-0461162GO:1990379
GeneOntologyBiologicalProcessproline biosynthetic process

PYCR1 PYCR2

4.63e-0461162GO:0006561
GeneOntologyBiologicalProcessglucose import in response to insulin stimulus

SLC27A1 SLC27A4

4.63e-0461162GO:0044381
GeneOntologyBiologicalProcesserythrocyte differentiation

TMEM14C TMEM14DP ACVR1B RHCE TMEM14B ALAS2

4.84e-041761166GO:0030218
GeneOntologyBiologicalProcesspositive regulation of hydrolase activity

RAPGEF6 NLRP1 APOA1 CLDN4 RET TBC1D20 DDX11 SERPINB3 SLC27A4 ARAP1

5.19e-0449911610GO:0051345
GeneOntologyBiologicalProcesscarboxylic acid transport

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC17A5 ABCC8 SLC27A1 SLC7A10 SLC27A4

5.20e-044101169GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC17A5 ABCC8 SLC27A1 SLC7A10 SLC27A4

5.38e-044121169GO:0015849
GeneOntologyBiologicalProcessalpha-amino acid metabolic process

GNMT TYR MTHFD1 PYCR1 PYCR2 ALDH6A1 ATP2B4

5.50e-042511167GO:1901605
GeneOntologyBiologicalProcessproteinogenic amino acid metabolic process

GNMT TYR MTHFD1 PYCR1 PYCR2 ATP2B4

6.30e-041851166GO:0170039
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

ATP7B STIMATE RYR1 RHCE SLC6A7 SLC2A10 SLC17A5 CACNG6 SLC41A3 ABCC8 KCNMB1 CACNA1H SEC61A1 ATP2B4

6.73e-0492211614GO:0098662
GeneOntologyBiologicalProcessregulation of small molecule metabolic process

TTC39B ACADVL OBP2A APOA1 GNMT ADRA1B SLC2A6 ATP2B4 SLC27A4

7.80e-044341169GO:0062012
GeneOntologyBiologicalProcesscell junction disassembly

ARF6 ABCC8 CD47

8.36e-04331163GO:0150146
GeneOntologyBiologicalProcessSRP-dependent cotranslational protein targeting to membrane, translocation

SEC61A2 SEC61A1

8.59e-0481162GO:0006616
GeneOntologyBiologicalProcesspyrimidine nucleobase catabolic process

DPYSL5 ALDH6A1

8.59e-0481162GO:0006208
GeneOntologyBiologicalProcesspost-translational protein targeting to membrane, translocation

SEC61A2 SEC61A1

8.59e-0481162GO:0031204
GeneOntologyBiologicalProcessorganic acid catabolic process

ACADVL OBP2A BDH2 LDHC ALDH6A1 ATP2B4 SLC27A4

8.82e-042721167GO:0016054
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

ACADVL OBP2A BDH2 LDHC ALDH6A1 ATP2B4 SLC27A4

8.82e-042721167GO:0046395
GeneOntologyBiologicalProcessalpha-amino acid biosynthetic process

MTHFD1 PYCR1 PYCR2 ATP2B4

9.37e-04771164GO:1901607
GeneOntologyBiologicalProcessintracellular iron ion homeostasis

BDH2 IREB2 ATP13A2 ALAS2

9.83e-04781164GO:0006879
GeneOntologyCellularComponentcyclin A2-CDK2 complex

CCNA2 CCNA1

9.13e-0531162GO:0097124
GeneOntologyCellularComponentsarcolemma

TRIM72 RYR1 ADRA1B CACNG6 ABCC8 CACNA1H ATP2B4

9.28e-051901167GO:0042383
GeneOntologyCellularComponentSec61 translocon complex

SEC61A2 SEC61A1

3.02e-0451162GO:0005784
GeneOntologyCellularComponenttranslocon complex

SEC61A2 SEC61A1

4.51e-0461162GO:0071256
GeneOntologyCellularComponentendoplasmic reticulum protein-containing complex

MARCHF6 RYR1 SEC61A2 NBAS SEC61A1

6.66e-041251165GO:0140534
MousePhenoabnormal vasoconstriction

SMTNL1 ADRA1B KCNMB1 CACNA1H ATP2B4

1.96e-0550935MP:0000250
MousePhenodecreased cellular hemoglobin content

TMEM14C TMEM14DP TMEM14B

3.31e-0510933MP:0008956
MousePhenoabnormal cellular hemoglobin content

TMEM14C TMEM14DP TMEM14B

6.00e-0512933MP:0008954
DomainTMEM14

TMEM14C TMEM14DP TMEM14B

2.14e-0651133IPR005349
DomainTmemb_14

TMEM14C TMEM14DP TMEM14B

2.14e-0651133PF03647
DomainPlug_translocon

SEC61A2 SEC61A1

3.63e-0521132PF10559
DomainSecY_su_dom

SEC61A2 SEC61A1

3.63e-0521132IPR023201
DomainSecY

SEC61A2 SEC61A1

3.63e-0521132PF00344
DomainSECY_1

SEC61A2 SEC61A1

3.63e-0521132PS00755
DomainSECY_2

SEC61A2 SEC61A1

3.63e-0521132PS00756
Domain-

SEC61A2 SEC61A1

3.63e-05211321.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A2 SEC61A1

3.63e-0521132IPR019561
DomainSecY_CS

SEC61A2 SEC61A1

3.63e-0521132IPR030659
DomainCyclin_A2_chordates

CCNA2 CCNA1

3.63e-0521132IPR015453
DomainSecY/SEC61-alpha

SEC61A2 SEC61A1

3.63e-0521132IPR002208
DomainPC_rep

PSMD1 ANAPC1

1.08e-0431132PF01851
Domain-

PYCR1 PYCR2

1.08e-04311321.10.3730.10
DomainP5CR_dimer

PYCR1 PYCR2

1.08e-0431132PF14748
DomainP5CR_dimer

PYCR1 PYCR2

1.08e-0431132IPR029036
DomainProteasome/cyclosome_rpt

PSMD1 ANAPC1

1.08e-0431132IPR002015
Domainvon_Ebner_gland

OBP2B OBP2A

1.08e-0431132IPR002450
DomainP5CR

PYCR1 PYCR2

2.16e-0441132PS00521
DomainPyrroline-COOH_reductase

PYCR1 PYCR2

2.16e-0441132IPR000304
DomainSUGAR_TRANSPORT_1

SLC2A10 MFSD14B SLC2A6

3.98e-04241133PS00216
DomainMFS

SLC16A9 SLC2A10 SLC17A5 MFSD14B SLC2A6

5.04e-041081135PS50850
DomainProC_N

PYCR1 PYCR2

7.47e-0471132IPR028939
DomainF420_oxidored

PYCR1 PYCR2

7.47e-0471132PF03807
DomainAMP-binding

DIP2A SLC27A1 SLC27A4

7.77e-04301133PF00501
DomainAMP-dep_Synth/Lig

DIP2A SLC27A1 SLC27A4

7.77e-04301133IPR000873
DomainSugar_transporter_CS

SLC2A10 MFSD14B SLC2A6

9.41e-04321133IPR005829
DomainATPase_P-typ_cyto_domN

ATP7B ATP13A2 ATP2B4

1.23e-03351133IPR023299
DomainP_typ_ATPase

ATP7B ATP13A2 ATP2B4

1.33e-03361133IPR001757
DomainATPase_P-typ_P_site

ATP7B ATP13A2 ATP2B4

1.33e-03361133IPR018303
DomainATPASE_E1_E2

ATP7B ATP13A2 ATP2B4

1.33e-03361133PS00154
DomainMFS_dom

SLC16A9 SLC2A10 SLC17A5 MFSD14B SLC2A6

1.33e-031341135IPR020846
DomainATPase_P-typ_transduc_dom_A

ATP7B ATP13A2 ATP2B4

1.44e-03371133IPR008250
DomainE1-E2_ATPase

ATP7B ATP13A2 ATP2B4

1.44e-03371133PF00122
DomainAA_permease_2

SLC7A8 SLC7A10

2.71e-03131132PF13520
DomainAA/rel_permease1

SLC7A8 SLC7A10

2.71e-03131132IPR002293
DomainSugar/inositol_transpt

SLC2A10 SLC2A6

3.15e-03141132IPR003663
Domain-

BDH2 LDHC MTHFD1 PYCR1 PYCR2

3.66e-0316911353.40.50.720
DomainNAD(P)-bd_dom

BDH2 LDHC MTHFD1 PYCR1 PYCR2

4.04e-031731135IPR016040
DomainSUGAR_TRANSPORT_2

SLC2A10 SLC2A6

4.65e-03171132PS00217
DomainLIPOCALIN

OBP2B OBP2A

4.65e-03171132PS00213
DomainCyclin_C

CCNA2 CCNA1

4.65e-03171132PF02984
DomainCyclin_C-dom

CCNA2 CCNA1

4.65e-03171132IPR004367
DomainAMP-bd_C

SLC27A1 SLC27A4

4.65e-03171132IPR025110
DomainAMP-binding_C

SLC27A1 SLC27A4

4.65e-03171132PF13193
DomainCyclin_C

CCNA2 CCNA1

4.65e-03171132SM01332
DomainCation_ATPase_N

ATP13A2 ATP2B4

5.21e-03181132SM00831
DomainLipocalin

OBP2B OBP2A

5.21e-03181132IPR002345
DomainATPase_P-typ_cation-transptr_N

ATP13A2 ATP2B4

5.80e-03191132IPR004014
Domain6-PGluconate_DH_C-like

PYCR1 PYCR2

5.80e-03191132IPR008927
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP7B SLC26A4 IREB2 PSMD1 APOA1 ANO10 ATP13A2 RYR1 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC2A6 SLC27A1 SLC7A10 ATP2B4 CA1 SLC27A4

5.25e-086818218MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP7B SLC26A4 IREB2 PSMD1 APOA1 ANO10 ATP13A2 RYR1 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC2A6 SLC27A1 SLC7A10 ATP2B4 CA1 SLC27A4

1.69e-077368218M27287
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A4 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC2A6 SLC27A1 SLC7A10 SLC27A4

9.62e-06238829MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A4 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC2A6 SLC27A1 SLC7A10 SLC27A4

1.38e-05249829M5988
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC26A4 PSMD1 APOA1 SLC2A10 SLC17A5 ABCC8 SLC27A4

7.52e-05177827M27476
PathwayREACTOME_G2_PHASE

CCNA2 CCNA1

3.30e-045822MM15365
PathwayREACTOME_G2_PHASE

CCNA2 CCNA1

3.30e-045822M27663
PathwayREACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION

CCNA2 PPP2R1B CCNA1

3.98e-0425823M808
PathwayREACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION

CCNA2 PPP2R1B CCNA1

3.98e-0425823MM15379
PathwayREACTOME_TRANSPORT_OF_FATTY_ACIDS

SLC27A1 SLC27A4

4.94e-046822MM15470
Pubmed

TMEM14C is required for erythroid mitochondrial heme metabolism.

TMEM14C TMEM14DP TMEM14B

3.62e-083116325157825
Pubmed

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.

MPO ATP7B ACADVL TMEM14C TMEM14DP NUDT9 MTHFD1 TMEM14B PYCR1 ALAS2 ACOT2 ALDH6A1

2.88e-075421161214651853
Pubmed

Identification of the Mitochondrial Heme Metabolism Complex.

TMEM14C TMEM14DP TMEM14B ALAS2

6.73e-0721116426287972
Pubmed

Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.

TMEM14C TMEM14DP TMEM14B

1.25e-067116319656490
Pubmed

Nutrient Transporter Gene Expression in the Early Conceptus-Implications From Two Mouse Models of Diabetic Pregnancy.

SLC2A10 SLC2A6 SLC27A1 SLC27A4

1.41e-0625116435478964
Pubmed

Two immunologically distinct human DNA polymerase alpha-primase subpopulations are involved in cellular DNA replication.

CCNA2 PPP2R1B CCNA1

7.78e-0612116311259605
Pubmed

A mitochondrial protein compendium elucidates complex I disease biology.

HIGD2A ACADVL COQ8B TMEM14C IREB2 TMEM14DP MTHFD1 TMEM14B TMEM65 PYCR1 ALAS2 ACOT2 ALDH6A1 METTL17

1.08e-0510471161418614015
Pubmed

The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases.

SERPINB3 SERPINB4

1.10e-052116215203214
Pubmed

Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure.

SERPINB3 SERPINB4

1.10e-052116223354406
Pubmed

Regulation of early embryo development: functional redundancy between cyclin subtypes.

CCNA2 CCNA1

1.10e-052116211545166
Pubmed

Serum levels of anti-apolipoprotein A-1 auto-antibodies and myeloperoxidase as predictors of major adverse cardiovascular events after carotid endarterectomy.

MPO APOA1

1.10e-052116223364307
Pubmed

Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions.

MPO APOA1

1.10e-052116222219194
Pubmed

Characterization of novel squamous cell carcinoma antigen-related molecules in mice.

SERPINB3 SERPINB4

1.10e-052116215504361
Pubmed

SCCA2-like serpins mediate genetic predisposition to skin tumors.

SERPINB3 SERPINB4

1.10e-052116212702576
Pubmed

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.

SERPINB3 SERPINB4

1.10e-052116235022507
Pubmed

A novel human odorant-binding protein gene family resulting from genomic duplicons at 9q34: differential expression in the oral and genital spheres.

OBP2B OBP2A

1.10e-052116210607840
Pubmed

SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.

SERPINB3 SERPINB4

1.10e-052116225111616
Pubmed

Myeloperoxidase-mediated Methionine Oxidation Promotes an Amyloidogenic Outcome for Apolipoprotein A-I.

MPO APOA1

1.10e-052116225759391
Pubmed

Squamous cell carcinoma antigen production in nasal inverted papilloma.

SERPINB3 SERPINB4

1.10e-052116223168150
Pubmed

Metabolic control of CD47 expression through LAT2-mediated amino acid uptake promotes tumor immune evasion.

SLC7A8 CD47

1.10e-052116236274066
Pubmed

Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 increase the cellular fatty acid uptake of 3T3-L1 adipocytes but are localized on intracellular membranes.

SLC27A1 SLC27A4

1.10e-052116223024797
Pubmed

Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma.

SERPINB3 SERPINB4

1.10e-052116214970861
Pubmed

The A-type cyclins and the meiotic cell cycle in mammalian male germ cells.

CCNA2 CCNA1

1.10e-052116215271198
Pubmed

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas.

SERPINB3 SERPINB4

1.10e-052116210653592
Pubmed

Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.

SERPINB3 SERPINB4

1.10e-052116229112685
Pubmed

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.

SERPINB3 SERPINB4

1.10e-052116210956412
Pubmed

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease.

SERPINB3 SERPINB4

1.10e-052116235874657
Pubmed

Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis.

SERPINB3 SERPINB4

1.10e-052116222406480
Pubmed

Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy.

SERPINB3 SERPINB4

1.10e-052116227668655
Pubmed

Control of translocation through the Sec61 translocon by nascent polypeptide structure within the ribosome.

SEC61A2 SEC61A1

1.10e-052116218480044
Pubmed

Distinct properties of cyclin-dependent kinase complexes containing cyclin A1 and cyclin A2.

CCNA2 CCNA1

1.10e-052116219056339
Pubmed

Evidence of an odorant-binding protein in the human olfactory mucus: location, structural characterization, and odorant-binding properties.

OBP2B OBP2A

1.10e-052116212044155
Pubmed

Anchorage-dependent expression of cyclin A in primary cells requires a negative DNA regulatory element and a functional Rb.

CCNA2 CCNA1

1.10e-052116210086336
Pubmed

Senolytics prevent caveolar CaV 3.2-RyR axis malfunction in old vascular smooth muscle.

RYR1 CACNA1H

1.10e-052116237837625
Pubmed

SH2B1beta adaptor is a key enhancer of RET tyrosine kinase signaling.

RET SH2B1

1.10e-052116217471236
Pubmed

The yeast cyclin-dependent kinase inhibitor Sic1 and mammalian p27Kip1 are functional homologues with a structurally conserved inhibitory domain.

CCNA2 CCNA1

1.10e-052116215649124
Pubmed

Serpinb3 is overexpressed in the liver in presence of iron overload.

SERPINB3 SERPINB4

1.10e-052116228935635
Pubmed

Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.

SERPINB3 SERPINB4

1.10e-052116221403642
Pubmed

Posttranscriptional regulation of cyclin A1 and cyclin A2 during mouse oocyte meiotic maturation and preimplantation development.

CCNA2 CCNA1

1.10e-052116211566717
Pubmed

Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter.

SERPINB3 SERPINB4

1.10e-052116211267667
Pubmed

Squamous Cell Carcinoma Antigen-encoding Genes SERPINB3/B4 as Potentially Useful Markers for the Stratification of HNSCC Tumours.

SERPINB3 SERPINB4

1.10e-052116229491058
Pubmed

The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases.

SERPINB3 SERPINB4

1.10e-052116211863458
Pubmed

IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease.

SERPINB3 SERPINB4

1.10e-052116222808225
Pubmed

Tumor-related protein, the squamous cell carcinoma antigen binds to the intracellular protein carbonyl reductase.

SERPINB3 SERPINB4

1.10e-052116220428762
Pubmed

Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.

PRPF31 ACADVL COQ8B SURF4 PYCR1 PYCR2 SEC61A1 ALDH6A1 SLC27A4

1.71e-05438116932628020
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC7A8 SLC2A10 SLC27A1 ATP2B4 SLC27A4

2.80e-05105116530280653
Pubmed

HPV16 E1--E4 protein is phosphorylated by Cdk2/cyclin A and relocalizes this complex to the cytoplasm.

CCNA2 CCNA1

3.30e-053116216540140
Pubmed

Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ.

OBP2B OBP2A

3.30e-05311627813422
Pubmed

Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor.

CCNA2 CCNA1

3.30e-053116212244298
Pubmed

Regulation of meiosis during mammalian spermatogenesis: the A-type cyclins and their associated cyclin-dependent kinases are differentially expressed in the germ-cell lineage.

CCNA2 CCNA1

3.30e-053116210068472
Pubmed

Fatty acid transporters in skin development, function and disease.

SLC27A1 SLC27A4

3.30e-053116224120574
Pubmed

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.

PYCR1 PYCR2

3.30e-053116226733354
Pubmed

Functional domains of the fatty acid transport proteins: studies using protein chimeras.

SLC27A1 SLC27A4

3.30e-053116218258213
Pubmed

Mitsugumin 53 regulates extracellular Ca2+ entry and intracellular Ca2+ release via Orai1 and RyR1 in skeletal muscle.

TRIM72 RYR1

3.30e-053116227841305
Pubmed

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.

PYCR1 PYCR2

3.30e-053116224930674
Pubmed

Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii.

SERPINB3 SERPINB4

3.30e-053116222451727
Pubmed

Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex.

CCNA2 CCNA1

3.30e-053116210679238
Pubmed

Expression of Six1 homeobox gene during development of the mouse submandibular salivary gland.

CCNA2 CCNA1

3.30e-053116219371398
Pubmed

Characterization of a second human cyclin A that is highly expressed in testis and in several leukemic cell lines.

CCNA2 CCNA1

3.30e-05311629041194
Pubmed

Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.

OBP2B OBP2A

3.30e-053116226592241
Pubmed

Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).

SERPINB3 SERPINB4

3.30e-053116224635038
Pubmed

Heparin enhances serpin inhibition of the cysteine protease cathepsin L.

SERPINB3 SERPINB4

3.30e-053116219959474
Pubmed

Cell cycle in mouse development.

CCNA2 CCNA1

3.30e-053116215838522
Pubmed

Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei.

TYR PROKR2

3.30e-053116217202262
Pubmed

Function of cyclins in regulating the mitotic and meiotic cell cycles in male germ cells.

CCNA2 CCNA1

3.30e-053116219001847
Pubmed

Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells.

SERPINB3 SERPINB4

3.30e-053116219070595
Pubmed

Functional specialization in proline biosynthesis of melanoma.

PYCR1 PYCR2

3.30e-053116223024808
Pubmed

Genetic analysis of Pycr1 and Pycr2 in mice.

PYCR1 PYCR2

3.30e-053116233734376
Pubmed

Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export.

MPO APOA1

3.30e-053116220064972
Pubmed

A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases.

SERPINB3 SERPINB4

3.30e-05311629828132
Pubmed

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

SERPINB3 SERPINB4

3.30e-05311627724531
Pubmed

Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel.

SERPINB3 SERPINB4

3.30e-053116224898082
Pubmed

Deubiquitinase DUB3 Regulates Cell Cycle Progression via Stabilizing Cyclin A for Proliferation of Non-Small Cell Lung Cancer Cells.

CCNA2 CCNA1

3.30e-053116230935108
Pubmed

A proteomic study of protein variation between osteopenic and age-matched control bone tissue.

APOA1 CA1

3.30e-053116222619369
Pubmed

A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.

SERPINB3 SERPINB4

3.30e-053116221126757
Pubmed

Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I.

MPO APOA1

3.30e-053116216497665
Pubmed

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts.

SLC27A1 SLC27A4

3.30e-053116215496455
Pubmed

Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast.

SLC27A1 SLC27A4

3.30e-053116215699031
Pubmed

Uteroglobin suppresses SCCA gene expression associated with allergic asthma.

SERPINB3 SERPINB4

3.30e-053116215677460
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

HIGD2A TTC28 COQ8B SEC61A2 ANAPC1 RRP12 HLTF PYCR1 SEC61A1 ANKRD52

3.74e-056061161036538041
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ATP7B HIGD2A TMEM221 COQ8B ACVR1B CACNG6 TM9SF2 MTHFD1 SLC2A6 SURF4 ATP2B4 CD99L2 SNX2

5.57e-0510611161333845483
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

ACADVL COQ8B ZZEF1 TMEM65 PYCR1 ACOT2 PYCR2 ANKRD52 SLC27A4

5.99e-05515116931617661
Pubmed

Evolutionarily conserved regulators of tau identify targets for new therapies.

ATP7B MARCHF6 PSMD1 TM9SF2 MTHFD1 SURF4 SEC61A1 SNX2 SLC27A4

6.08e-05516116936610398
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MYH1 ACADVL PSMD1 PPP2R1B NCAPG TM9SF2 MTHFD1 SURF4 SEC61A1 ATP2B4

6.45e-056471161026618866
Pubmed

Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells.

SLC27A1 SLC27A4

6.59e-054116221395585
Pubmed

Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.

MTHFD1 ALDH6A1

6.59e-054116225099943
Pubmed

An increase in expression of the lipocalin 24p3 is found in mouse uterus coincident with birth.

OBP2B OBP2A

6.59e-05411627544071
Pubmed

Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase.

SERPINB3 SERPINB4

6.59e-054116216549498
Pubmed

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.

SERPINB3 SERPINB4

6.59e-054116221576355
Pubmed

Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription.

CCNA2 CCNA1

6.59e-054116211598016
Pubmed

Genetic analysis of the rhabdomyolysis-associated genes in forensic autopsy cases of methamphetamine abusers.

ACADVL RYR1

6.59e-054116220952238
Pubmed

Mouse emi1 has an essential function in mitotic progression during early embryogenesis.

CCNA2 CCNA1

6.59e-054116216809773
Pubmed

BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site.

CCNA2 CCNA1

6.59e-054116210373534
Pubmed

The Sec61 complex is located in both the ER and the ER-Golgi intermediate compartment.

SEC61A2 SEC61A1

6.59e-054116210212142
Pubmed

Distinct roles for the mammalian A-type cyclins during oogenesis.

CCNA2 CCNA1

6.59e-054116216183859
Pubmed

Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.

SERPINB3 SERPINB4

6.59e-054116212949073
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RAPGEF6 TTC28 TMEM14C TMEM14DP ZZEF1 DIP2A TMEM14B HLTF SEC61A1 SLC27A4

6.70e-056501161038777146
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PRPF31 PSMD1 NCAPG TM9SF2 ANAPC1 MTHFD1 SERPINB3 SURF4 RRP12 CD47 PYCR1 PYCR2 SEC61A1 SNX2 SLC27A4

8.11e-0514251161530948266
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

ATP7B PSMD1 ANO10 ARF6 MTHFD1 SURF4 PYCR1 ACOT2 PYCR2 SEC61A1 ATP2B4 CD99L2

8.37e-059521161238569033
Pubmed

Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator.

CCNA2 CCNA1

1.10e-045116215601848
Cytoband18q21.3

SERPINB3 SERPINB4

3.43e-0411116218q21.3
Cytoband9q34

OBP2B OBP2A SLC2A6

3.55e-045411639q34
GeneFamilySolute carriers

SLC16A9 SLC26A4 SLC7A8 SLC6A7 SLC2A10 SLC17A5 SLC41A3 SLC2A6 SLC27A1 SLC7A10 SLC27A4

8.64e-073957711752
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TCEA3 SLC26A4 CLDN4 SLC2A10 SERPINB3 PYCR1 TMEM238 TMEM125

5.22e-082001158292c63693eb7f435335a8cfba07aa35b72139393
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

TRIM72 TCEA3 MYH1 RYR1 SLC7A8 SLC6A7 CACNG6

1.61e-071551157d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Polychromatic_Erythroblast|World / Lineage, cell class and subclass

ATP7B SLC16A9 RHCE CCNA2 NCAPG ALAS2 CA1

7.35e-071941157008bb0072f414a48d052429101bdc990ee4f80c2
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor-erythroid_progenitor_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMEM14C RHCE MTHFD1 TMEM14B PYCR1 ALAS2 CA1

7.88e-071961157e994aa72b362a4f4930b94505a99c0a87e9b163c
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor-erythroid_progenitor_cell|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMEM14C RHCE CCNA2 NCAPG TMEM14B ALAS2 CA1

7.88e-071961157c391d6359634145455c71c7f051bf34ff0eb666d
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Mucous-Mucous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCEA3 SLC16A9 GNMT SLC2A10 PYCR1 TMEM238 TMEM125

7.88e-071961157357a5440aeebf69688bfe9fbc8585950ad00906b
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega|bone_marrow / Manually curated celltypes from each tissue

SLC16A9 TMEM14C CCNA2 TMEM14B PYCR1 ALAS2 CA1

7.88e-071961157707eecbb2b14051fd843afa66035014ec59e6bd5
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Mucous|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCEA3 SLC16A9 GNMT SLC2A10 PYCR1 TMEM238 TMEM125

7.88e-07196115798e3f9c886063def16c74ab75fc81511a7872f1c
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic_early|bone_marrow / Manually curated celltypes from each tissue

SLC16A9 TMEM14C CCNA2 TMEM14B PYCR1 ALAS2 CA1

7.88e-071961157507254c4c00e535fe01851431b5b74a5f15d9592
ToppCellerythropoietic-Erythrocyte|World / Lineage and Cell class

TMEM14C RHCE CCNA2 TMEM14B PYCR1 ALAS2 CA1

7.88e-0719611571642d9340f621cd55987ef8154b48aa306f0f0c8
ToppCellerythropoietic|World / Lineage and Cell class

TMEM14C RHCE CCNA2 HLTF PYCR1 ALAS2 CA1

8.15e-071971157a52546cebc222050c970e04cec97e4f48ab8fe10
ToppCellerythropoietic-Polychromatic_Erythroblast|World / Lineage and Cell class

RHCE CCNA2 NCAPG HLTF PYCR1 ALAS2 CA1

8.15e-071971157604fcbf47f073c2af344e1b16b615a78ef838dc9
ToppCelldroplet-Liver-LIVER-NPC-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA3 ACADVL SLC26A4 APOA1 GNMT CLIP4

6.72e-0617711561b077084b78e62ead603f72c9db6ce74a3953f81
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 DPYSL5 RYR1 NBAS PYCR1 CACNA1H

8.13e-061831156b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ATP7B TMEM14C RHCE TMEM14B ALAS2 CA1

8.38e-0618411560efc757d9512d6a8fe8176e977a94e4494ed9778
ToppCell10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Erythrocytic_early|lymph-node_spleen / Manually curated celltypes from each tissue

RHCE CCNA2 SLC2A10 PYCR1 ALAS2 CA1

9.19e-06187115661d346c9873c2edb3ce224a0c063c54d9a68309e
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-early_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATP7B SLC16A9 TMEM14C TMEM14B PYCR1 CA1

1.04e-051911156246eff3f68e755c11393f77074a49b98ff138d11
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLDN4 CCNA2 NCAPG SERPINB3 SERPINB4 TMEM238

1.24e-0519711562430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCellerythropoietic-Basophilic_Erythroblast|World / Lineage and Cell class

SLC16A9 CCNA2 MTHFD1 HLTF PYCR1 CA1

1.27e-051981156b3db4db02c0e659163cefb3d83f53e4940cc04bf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC26A4 TMEM200A RYR1 SLC6A7 CACNA1H

3.17e-0514011557cc891d676555609add6fc7880735d948a2ad801
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SLC26A4 TMEM200A RYR1 SLC6A7 CACNA1H

3.62e-05144115508005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Npsr1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPYC SLC26A4 RYR1 CACNA1H

5.79e-058111545d9b08bc1ae6ecb894c88c9784fdc4203682d087
ToppCelldroplet-Limb_Muscle-nan-24m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO LDHC CCNA2 NCAPG SLC27A4

5.81e-05159115539033d49501a4ecc00af6c256e7a569c903ad332
ToppCelldroplet-Heart-nan-18m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RYR1 CCNA2 NCAPG SLC2A6 ALAS2

6.34e-0516211557f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_small-bowel / Manually curated celltypes from each tissue

MPO TCEA3 APOA1 CLDN4 CA1

6.53e-0516311551a8c79903ed416f286ebe8a9922233affbc55d82
ToppCell390C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LDHC CCNA2 DDX11 NCAPG CA1

6.53e-051631155aa5ea367f787c1543afb7eb80a801432e1c44011
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA3 ACADVL APOA1 GNMT ALAS2

6.92e-051651155dba630e205eb3725195f8861e4af5b745ccfdc74
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA3 ACADVL APOA1 GNMT ALAS2

6.92e-051651155a508d66031c1a46b062afbee3cde1cbd0c163a03
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA3 ACADVL APOA1 GNMT ALAS2

6.92e-051651155b03c8c3110f32257e78838885b313a922af73c98
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC16A9 RYR1 SLC7A8 ALDH6A1 NLRP5

7.33e-0516711553edb0570e583bb527165bcd8a4c25a042054043b
ToppCellmild_COVID-19_(asymptomatic)-RBC|World / disease group, cell group and cell class (v2)

SOWAHD NUDT9 SEC61A2 ALAS2 ALDH6A1

7.75e-0516911552bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO10 RET CCNA2 NCAPG ABCC8

8.19e-051711155913bae728b5e653771a27c79a309eb023699f1d0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO10 RET CCNA2 NCAPG ABCC8

8.19e-051711155f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellmild_COVID-19_(asymptomatic)-RBC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

SOWAHD NUDT9 SEC61A2 ALAS2 ALDH6A1

8.19e-05171115578491478ba65bad45238fe114f5251b2adea323d
ToppCellfacs-Marrow-T-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 PROKR2 PYCR1 CACNA1H NLRP5

9.13e-0517511550a01e0104cfa3091bc05b0f1d087c941688169a5
ToppCellRSV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

SOWAHD CCNA2 ARL4C NCAPG PYCR1

9.13e-051751155c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCellRSV-Healthy-2|RSV / Virus stimulation, Condition and Cluster

SOWAHD CCNA2 ARL4C NCAPG PYCR1

9.13e-0517511550e97189585b7afaf3bd622c3ef10c86412393829
ToppCellHealthy-RBC|Healthy / disease group, cell group and cell class

RHCE PPP2R1B NCAPG ALAS2 CA1

9.63e-051771155945d72ab52efa9a9468daace9f9ec676a891d963
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-early_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ATP7B SLC16A9 TMEM14C TMEM14B CA1

1.02e-0417911553f73f89905c061ada4e3eb921fa394d95f95c959
ToppCellfacs-Marrow-T-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 PROKR2 PYCR1 CACNA1H NLRP5

1.02e-0417911553f2934c5f8816a7b7a6aef8d2f83ebf7b2b693bf
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO SLC26A4 APOA1 GNMT ALAS2

1.10e-04182115581c394959414173016426961478f670cd822f8b3
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPO SLC26A4 APOA1 GNMT ALAS2

1.10e-04182115541a7543c8b703441ff6ac2307faffe5f798b2c41
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

DPYSL5 SLC6A7 ARL4C ADRA1B ABCC8

1.10e-04182115504ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic_early|bone_marrow / Manually curated celltypes from each tissue

SLC16A9 TMEM14C PYCR1 ALAS2 CA1

1.13e-041831155d43ba3fbbd9132125fa2b7ea0891a2c577974f14
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A4 CLDN4 SERPINB3 SERPINB4 TMEM238

1.16e-04184115501c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellCOVID-cycling-|COVID / Condition, Cell_class and T cell subcluster

RHCE CCNA2 NCAPG ALAS2 CA1

1.19e-041851155eb74b8d36f7b749e04bc2ed4b36f7e1ac7bb6d5f
ToppCellCOVID-cycling|COVID / Condition, Cell_class and T cell subcluster

RHCE CCNA2 NCAPG ALAS2 CA1

1.19e-0418511555112f966735fa48f0606adcfd5c0212ad5d3d77a
ToppCell18-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

SLC16A9 CLDN4 ARL4C SERPINB3 SERPINB4

1.25e-041871155d1e301afcc39054ae1f867d80e564e30a137e3f8
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZZEF1 SH3TC1 MCM9 HLTF ATP2B4

1.25e-041871155816d37a70f7ec382a268fe828b3dfe737a36a4bf
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-plasma_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A5 SURF4 PYCR1 CACNA1H SEC61A1

1.34e-041901155992539c380576bf810c00a5f926cf1ee7d57dcf5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A4 CLDN4 SERPINB3 SERPINB4 TMEM238

1.34e-04190115523f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCNA2 RNF123 NCAPG ALAS2 ATP2B4

1.34e-0419011554288189e3a499c395896c950598810b02f401685
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A4 CLDN4 SERPINB3 SERPINB4 TMEM238

1.34e-0419011553c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RYR1 CCNA2 SERPINB3 SERPINB4 TMEM238

1.38e-0419111550f9443da0f73d07456142fae08b2dc92a5b7b592
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 CLIP4 ADRA1B ABCC8 CACNA1H

1.38e-041911155c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CCNA2 NCAPG MTHFD1 CCNA1 SLC7A10

1.38e-04191115556b45259dfc38bd5ea43b0e3adf47e7e2c043a5d
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Hematologic-erythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM14C NUDT9 CCNA2 ALAS2 PYCR2

1.38e-04191115524ebc8d4a9fc3782510162e04fe586f7cb371eed
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM72 CLIP4 ADRA1B ABCC8 CACNA1H

1.38e-041911155715f5b449b8e075959c05a5b38389df319663164
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RET TM9SF2 MTHFD1 ABCC8 TMEM65

1.41e-0419211555b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLC16A9 RHCE TMEM14B ALAS2 CA1

1.41e-0419211556ace9a34ed264583042156ed61c2cb3504a331d2
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid-early_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ATP7B SLC16A9 TMEM14C TMEM14B PYCR1

1.41e-041921155f29d3d5223fccec3e34ab6582e9503adb14be543
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

TCEA3 SOWAHD SLC7A8 ACOT2 SNX2

1.44e-041931155c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC26A4 CLDN4 RET GNMT CLIP4

1.44e-0419311554a1b4a2faf741ffba5c84218af4df6a8b2a9f4de
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC26A4 CLDN4 RET GNMT CLIP4

1.44e-04193115568adc680deb2f1a29d3cca19c13b9f6271dd4d60
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC26A4 CLDN4 RET GNMT CLIP4

1.44e-041931155819e6ee2ffa3e31bf9a2d57c99d9e3eac7072765
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLC16A9 TMEM14C RHCE TMEM14B ALAS2

1.52e-041951155b24f6fe71fbcffe7ff1fd1374455c378837d6313
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TCEA3 SLC16A9 SLC26A4 CLDN4 SERPINB3

1.55e-041961155c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TMEM14C RHCE RNF123 TMEM14B ALAS2

1.55e-0419611550aae78e73d53416d857bdf21f595a0a0a0ba7944
ToppCell10x3'2.3-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TMEM14C RHCE RNF123 TMEM14B ALAS2

1.55e-0419611552aeb792e7685e33e3543a6974be790980a41ed8c
ToppCell(2)_B_cells-(2)_Plasma_cells|(2)_B_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

ACADVL PSMD1 SURF4 PYCR1 SEC61A1

1.55e-041961155cc4f59b885d58e43471e85c51d8e366e68d10846
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLDN4 CCNA2 NCAPG SERPINB3 SERPINB4

1.59e-0419711551d4ccca2ff46fccb3ac052b5148cb7f94231d65a
ToppCellSevere|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ACADVL CCNA2 SURF4 PYCR1 SEC61A1

1.59e-041971155df3f58b58f82c42c65b0a09c054b669b34502037
ToppCell21-Trachea-RBC|Trachea / Age, Tissue, Lineage and Cell class

RHCE CCNA2 RNF123 NCAPG ALAS2

1.59e-0419711559f8eb6305ade0654bbcd8f19963be0b64af083de
ToppCell21-Trachea-RBC-RBC|Trachea / Age, Tissue, Lineage and Cell class

RHCE CCNA2 RNF123 NCAPG ALAS2

1.59e-0419711554710b55806a618076a954190f519e49c55d300d3
ToppCellEpithelial_cells-Epithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TCEA3 SLC16A9 BDH2 SLC7A8 ALDH6A1

1.63e-04198115552e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCellPSB-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TCEA3 SLC16A9 SURF4 PYCR1 SEC61A1

1.63e-041981155e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC16A9 CLDN4 SERPINB3 SERPINB4 TMEM238

1.63e-0419811553cc9e671f596ef0829684018e4257571fefb6267
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-early_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TMEM14C RHCE TMEM14B HLTF PYCR1

1.63e-0419811558d900a17667a41bdfa683a34275fe4c059f6a8ef
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tfh|lymph-node_spleen / Manually curated celltypes from each tissue

RAPGEF6 TMEM200A ARL4C SH3TC1 PCNX1

1.63e-041981155fbdd37ca3d4b61f266bf6146662cb300ef67b850
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMEM14C TMEM14B HLTF ALAS2 CA1

1.63e-0419811558be58e41ae7870d268e7ce5ab937769e2ecb60d9
ToppCellEpithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

TCEA3 SLC16A9 BDH2 SLC7A8 ALDH6A1

1.63e-041981155eeec789d226171f30799577cc37c07bdced2e3cb
ToppCellcellseq2-Epithelial|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCEA3 CLDN4 PYCR1 TMEM238 TMEM125

1.67e-0419911552d4fb558845764f937efaf39962caaeb2c85478b
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TCEA3 CLDN4 GNMT PYCR1 TMEM125

1.67e-041991155f37114cf849837fdb8ed9a767de773e8681b7df3
ToppCellcellseq2-Epithelial-Epithelial_Glandular|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TCEA3 CLDN4 PYCR1 TMEM238 TMEM125

1.67e-041991155ca78fd6e310232b25b864ed02ff9242fe1aa8206
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TCEA3 SLC16A9 CLDN4 SERPINB3 SERPINB4

1.67e-041991155ec1e110671e7725f752163c7241dbbf638dec2b2
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP7B SLC16A9 CLDN4 SERPINB3 TMEM125

1.67e-0419911557223f853335492ca617dbec3e4b6872a8a463a45
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TCEA3 ATP7B SLC16A9 SERPINB3 TMEM125

1.67e-041991155e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCelldistal-2-Epithelial-Mucous|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SLC26A4 CLDN4 SERPINB3 SERPINB4 PYCR1

1.67e-041991155c0275b5011c2bb08e873955afe2e213ec8070d0e
ToppCellcritical-Lymphoid-NKT-proliferating|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CLDN4 CCNA2 NCAPG SERPINB3 SERPINB4

1.67e-0419911559284956d852e434a91be892e88e06a7c71f8c583
ToppCell(2)_B_cell-(20)_B_cell_IgA_Plasma|(2)_B_cell / shred on Cell_type and subtype

ACADVL PSMD1 SURF4 PYCR1 SEC61A1

1.71e-04200115542afce995f9a7de0406cc836e1f09b3f168a066c
ToppCellcontrol-Lymphoid-NKT-proliferating|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CLDN4 NCAPG SERPINB3 SERPINB4 TMEM238

1.71e-042001155f8b5e5464b2ffef7b0ce75f60839c8ef791e17ba
ToppCellTracheal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TCEA3 CLDN4 GNMT PYCR1 TMEM125

1.71e-042001155a3e044468de437948b63c517e0a4773cc247c906
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TCEA3 CLDN4 SERPINB3 PYCR1 TMEM125

1.71e-0420011558f811ddd84c037a250d124496b0fbb2e4717011c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

CLDN4 RYR1 TYR SLC7A8 DNAH12

1.71e-04200115513ec8afea86e4a10599c924871ba4e325b0a8013
Drugmeridianin G

RET CCNA2 CCNA1

2.48e-0661153CID000400433
Drugicariside I

CCNA2 TYR CCNA1

2.48e-0661153CID005745470
Diseaseautosomal recessive cutis laxa type IIB (implicated_via_orthology)

PYCR1 PYCR2

1.45e-0521132DOID:0070137 (implicated_via_orthology)
Diseaseodorant-binding protein 2b measurement

OBP2B OBP2A

1.44e-0451132EFO_0801859
DiseaseHypoxemia

MPO ACADVL APOA1

2.74e-04331133C0700292
DiseaseHypoxia

MPO ACADVL APOA1

2.74e-04331133C0242184
DiseaseAnoxemia

MPO ACADVL APOA1

2.74e-04331133C0003129
DiseaseAnoxia

MPO ACADVL APOA1

2.74e-04331133C0003130
Diseaseanemia (biomarker_via_orthology)

IREB2 ALAS2

3.01e-0471132DOID:2355 (biomarker_via_orthology)
Diseaseplatelet endothelial cell adhesion molecule measurement

SLC2A6 SURF4

5.14e-0491132EFO_0010598
Diseaseretinal nerve fibre layer thickness measurement

TYR NBAS ALDH6A1

6.04e-04431133EFO_0600004
Diseasepancreatic cancer (is_marker_for)

APOA1 CLDN4 ACVR1B RET

6.26e-041011134DOID:1793 (is_marker_for)
Diseasehepatocellular carcinoma (implicated_via_orthology)

ATP7B GNMT MCM9

8.86e-04491133DOID:684 (implicated_via_orthology)
Diseaseprotein FAM3D measurement

OBP2B SLC2A6

9.36e-04121132EFO_0021869
DiseaseSquamous cell carcinoma of the head and neck

ATP7B CCNA2 CCNA1

1.05e-03521133C1168401
Diseaseundecenoylcarnitine (C11:1) measurement

SLC16A9 ACOT2

1.10e-03131132EFO_0800588
DiseaseCD209 antigen measurement

OBP2B SLC2A6

1.28e-03141132EFO_0008077
Diseasehyperinsulinism (biomarker_via_orthology)

IREB2 SLC27A1

1.48e-03151132DOID:2018 (biomarker_via_orthology)
DiseaseHepatitis

ATP7B GNMT

1.48e-03151132C0019158
Diseaseretinal layer thickness measurement

TYR NBAS ALDH6A1

1.60e-03601133EFO_0600002
Diseasebasophil measurement

SLC7A8 CCNA1 SLC7A10

1.60e-03601133EFO_0803539
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

OBP2B SLC2A6

1.90e-03171132EFO_0008011
Diseaseprogression free survival, ovarian carcinoma

NBAS TMEM14B

2.14e-03181132EFO_0001075, EFO_0004920
Diseasevitiligo (is_implicated_in)

NLRP1 TYR

2.91e-03211132DOID:12306 (is_implicated_in)
DiseaseHbA1c measurement, response to sulfonylurea

SLC16A9 OBP2A

2.91e-03211132EFO_0004541, EFO_0007922
Diseasebreast cancer, COVID-19

TTC28 OBP2B

3.19e-03221132MONDO_0007254, MONDO_0100096
Diseasee-selectin measurement

OBP2B SLC2A6

3.19e-03221132EFO_0004575
DiseaseLung diseases

MPO RET LDHC

3.38e-03781133C0024115
DiseaseMorbilliform Drug Reaction

MPO APOA1

3.49e-03231132C0406537
DiseaseDrug Eruptions

MPO APOA1

3.49e-03231132C0011609
Diseaseage of onset of asthma

TTC28 TM9SF2 SLC7A10

3.50e-03791133OBA_2001001

Protein segments in the cluster

PeptideGeneStartEntry
ALASVIMGLSTILGK

PPP2R1B

356

P30154
IVMLGLDSAGKTTVL

ARL4C

16

P56559
IQDMFTGGKLLALSL

SLC7A10

186

Q9NS82
VLSVLVALMAGKAEI

ATP7B

516

P35670
IEGMIKLALSAASGL

ACVR1B

301

P36896
RASLLAGKGFAVMAL

ACOT2

236

P49753
KAAKTLGIVVGMFIL

ADRA1B

291

P35368
MKAAVLTLAVLFLTG

APOA1

1

P02647
MLLGALGAKIVNSRD

ANKRD52

841

Q8NB46
AMLTSLGLKLGDRVV

CLIP4

276

Q8N3C7
AAVIAVLGLAVMALG

CACNG6

141

Q9BXT2
LTRLAVQIGKAGLLM

ATP2B4

356

P23634
VQIGKAGLLMSALTV

ATP2B4

361

P23634
MLAAGLLAKKAVEAG

IREB2

521

P48200
GAQALLGAAKMLLHS

PYCR1

206

P32322
FLLTGGLLIIAMVKS

KCNMB1

166

Q16558
TAGKLLALALIIIMG

SLC7A8

191

Q9UHI5
LVGASKIRMLLGAEA

ANO10

71

Q9NW15
IGLLLGVSAAKLGTM

ANAPC1

1206

Q9H1A4
IMTAVGKLLLGILAD

SLC16A9

351

Q7RTY1
GATMLLAKLLQDSGA

ALDH6A1

216

Q02252
KTGLLMIALGVIFLN

MAGEB18

196

Q96M61
LGAVKVAATLTAMGL

SLC2A10

276

O95528
MKTLAGLVLGLVIFD

EPYC

1

Q99645
TELGALMITVAGLKL

PCNX1

1386

Q96RV3
NRILAMGLGILTKSF

OR51I1

141

Q9H343
MAGRLLGKALAAVSL

NUDT9

1

Q9BW91
GGLTAEMKLLLALAG

MPO

21

P05164
LDGAIISTFLKMGIL

NLRP1

596

Q9C000
GMRAVKAVLVAAGNL

DNAH12

1426

Q6ZR08
AIGLSVMDLVGSILK

LDHC

251

P07864
GVLHAKIIAAITLMG

MARCHF6

766

O60337
AMKTLALLFVGATGA

MYH1

616

P12882
MKVAGGLELGAAALL

NLRP5

1

P59047
KNIASMVRAGGLLVI

GNMT

161

Q14749
VTGALLLSVVGGKMS

DDX11

766

Q96FC9
MKTLFLGVTLGLAAA

OBP2A

1

Q9NY56
VLIAALTMDLAGRKV

SLC2A6

326

Q9UGQ3
IMKIISALSGGSADL

NBAS

2041

A2RRP1
MVLSGALESVRLLKG

ALAS2

426

P22557
AAILLGLAVTAMKSR

HIGD2A

91

Q9BW72
MKTLFLGVTLGLAAA

OBP2B

1

Q9NPH6
MKFVAALSVLALLGT

ATP13A2

426

Q9NQ11
TIAGVASALAMALIG

CD99L2

186

Q8TCZ2
ASKADGLAVIGVLMK

CA1

136

P00915
VLRGKLQLVGTAAML

CCNA1

281

P78396
AVLKMSAALPAGLFA

COQ8B

256

Q96D53
MAAALALVAGVLSGA

CLPSL2

1

Q6UWE3
MKGILVAGITAVLVA

LYPD8

1

Q6UX82
ILADDMGLGKTLTAI

HLTF

291

Q14527
MGLGKTLTAIAVILT

HLTF

296

Q14527
GMDEKTIALLVAGLV

CD47

171

Q08722
ASMIVGNLVAGKRIA

DIP2A

951

Q14689
GKLQLVGTAAMLLAS

CCNA2

251

P20248
MAVKLGTLLLALALG

ENPP6

1

Q6UWR7
LVDIVVAMASAGGAK

CACNA1H

1376

O95180
VAMASAGGAKILGVL

CACNA1H

1381

O95180
KMLLGFGILGTAVLT

SLC17A5

136

Q9NRA2
VLKLVSTLLVMGIFG

RYR1

1841

P21817
AAMLVLAEKLLKGGS

METTL17

221

Q9H7H0
GVSGALTVLMKDAIK

MTHFD1

606

P11586
LAIKLMTNLALGRGA

CTU2

271

Q2VPK5
LGSVISVLADAAMGK

KIF28P

286

B7ZC32
GSVKIAAFIAMVGIL

MFSD14B

286

Q5SR56
ELLLMVAGEVKSALG

DIPK1C

146

Q0P6D2
MLANSASVRILIKGG

DPYSL5

1

Q9BPU6
AGSMVLAAVLLKLGG

MT-ND4

226

P03905
KLAVAMVLAGGIQRT

MCM9

321

Q9NXL9
MLSRLKAAQLVLTGG

SH2B1

531

Q9NRF2
LSGAGILRMVNKAAD

SNX2

276

O60749
ILLSGSVLVKGSMVL

RAPGEF6

76

Q8TEU7
TSGLIMQLLAGAKII

SEC61A2

86

Q9H9S3
MIATGGVITGLAALK

TMEM200A

1

Q86VY9
MRKLVDLAAGGATAA

RIPPLY1

71

Q0D2K3
AAGLALGLVMLGSKN

PSMD1

511

Q99460
ARGAAKKAGLLMALA

SH3TC1

546

Q8TE82
LAMVISSFGGLILSK

SLC41A3

291

Q96GZ6
GAQALLGAAKMLLDS

PYCR2

206

Q96C36
IVGTALMILVAIGFK

SURF4

186

O15260
MVIKVLVGALGADAT

SOWAHD

201

A6NJG2
SALGMVLLGAKDNTA

SERPINB3

36

P29508
VAISFKGLARTLGMA

RRP12

636

Q5JTH9
KGAGAAMLLIVGLVA

SLC6A7

116

Q99884
SLLLAALGEMQKVSG

ABCC8

721

Q09428
AALAGTMRGIIAKAV

ACADVL

346

P49748
MGRLDGKVIILTAAA

BDH2

1

Q9BUT1
ILMLGLDAAGKTTIL

ARF6

16

P62330
LGAIQKAAASMGDTL

ARAP1

946

Q96P48
KTMIVAGVVFLLAGL

CLDN4

116

O14493
AAEGLAKLMFSGLLV

NCAPG

711

Q9BPX3
LIAGASLLMVAKVGV

TMEM14C

91

Q9P0S9
VKLGSGAFNLMLSLL

TTC39B

301

Q5VTQ0
MSVLISAGAVLGKVN

RHCE

121

P18577
KAAGAAIGGVKNMLL

SMTNL1

371

A8MU46
ISAAIVMIAILALGK

SLC26A4

426

O43511
LGLAKAGMEAALLNV

SLC27A1

146

Q6PCB7
MLLGASLVGVLLFSK

SLC27A4

1

Q6P1M0
TSGLIMQLLAGAKII

SEC61A1

86

P61619
AVLMSFLLGIVEKGT

RNF123

336

Q5XPI4
IIIGASTAAKIMGVA

PRPF31

221

Q8WWY3
VGLIAGASLLMAAKV

TMEM14DP

91

A8MWL7
AAMVGAVLTALLAGL

TYR

481

P14679
SALGMVLLGAKDNTA

SERPINB4

36

P48594
AAKIVIGIALAGIML

PROKR2

51

Q8NFJ6
NVLSGAISAGLIAKM

TCEA3

256

O75764
QGLLGVVAFSTLMLK

STIMATE

41

Q86TL2
LGKMRVFLAALEGSL

TRIM72

176

Q6ZMU5
VGLIAGASLLMAAKV

TMEM14B

91

Q9NUH8
SITVLLSLGIMGDAK

TRAV26-2

6

A0A0B4J265
MAKATSGAAGLRLLL

RET

1

P07949
LGISTMAAAALGNLV

TMEM65

151

Q6PI78
MKVLATSFVLGSLGL

TMEM81

1

Q6P7N7
LLNGLKASAALGEAM

TTC28

1676

Q96AY4
VETGSMGARLVAAKL

TM9SF2

221

Q99805
AAMTLLGIAAAVLAA

TMEM221

11

A6NGB7
LLAFALARGSVAKVM

ZZEF1

476

O43149
RFVKLAVMGLTVALG

TBC1D20

366

Q96BZ9
AVMGLTVALGAAALA

TBC1D20

371

Q96BZ9
AVALDVAGMAALLTG

TMEM238

41

C9JI98
AMLSVGIALAALGSL

TMEM125

146

Q96AQ2
AAAALAAMNGRKILG

TIAL1

61

Q01085