Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cytoskeletal protein binding	SPTBN5 DLG5 BICDL1 SPTAN1 SPTBN2 KLC2 TRIOBP EPS8L3 PLEC KLC4 OGG1 KIFC2	1.01e-05	1099	49	12	GO:0008092
GeneOntologyMolecularFunction	actin filament binding	SPTBN5 SPTAN1 SPTBN2 TRIOBP EPS8L3 PLEC	1.88e-05	227	49	6	GO:0051015
GeneOntologyMolecularFunction	retinoic acid-responsive element binding	RXRB RXRG	1.23e-04	7	49	2	GO:0044323
GeneOntologyMolecularFunction	kinesin binding	SPTBN5 KLC2 KLC4	3.33e-04	55	49	3	GO:0019894
GeneOntologyMolecularFunction	dynactin binding	SPTBN5 BICDL1	3.83e-04	12	49	2	GO:0034452
GeneOntologyMolecularFunction	actin binding	SPTBN5 SPTAN1 SPTBN2 TRIOBP EPS8L3 PLEC	1.08e-03	479	49	6	GO:0003779
GeneOntologyMolecularFunction	cadherin binding	TBC1D10A SPTAN1 SPTBN2 KLC2 PLEC	1.42e-03	339	49	5	GO:0045296
GeneOntologyMolecularFunction	nuclear steroid receptor activity	RXRB RXRG	1.71e-03	25	49	2	GO:0003707
GeneOntologyBiologicalProcess	negative regulation of protein depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	2.19e-06	89	49	5	GO:1901880
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	3.90e-06	100	49	5	GO:0043242
GeneOntologyBiologicalProcess	actin filament capping	SPTBN5 SPTAN1 SPTBN2 TRIOBP	4.26e-06	46	49	4	GO:0051693
GeneOntologyBiologicalProcess	regulation of protein depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	4.96e-06	105	49	5	GO:1901879
GeneOntologyBiologicalProcess	negative regulation of actin filament depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP	7.00e-06	52	49	4	GO:0030835
GeneOntologyBiologicalProcess	regulation of actin filament depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP	1.33e-05	61	49	4	GO:0030834
GeneOntologyBiologicalProcess	actin filament depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP	1.82e-05	66	49	4	GO:0030042
GeneOntologyBiologicalProcess	protein depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	2.30e-05	144	49	5	GO:0051261
GeneOntologyBiologicalProcess	regulation of protein-containing complex disassembly	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	2.30e-05	144	49	5	GO:0043244
GeneOntologyBiologicalProcess	negative regulation of actin filament polymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP	3.02e-05	75	49	4	GO:0030837
GeneOntologyBiologicalProcess	regulation of actin filament polymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	3.38e-05	156	49	5	GO:0030833
GeneOntologyBiologicalProcess	regulation of actin polymerization or depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	6.18e-05	177	49	5	GO:0008064
GeneOntologyBiologicalProcess	negative regulation of protein polymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP	6.45e-05	91	49	4	GO:0032272
GeneOntologyBiologicalProcess	regulation of actin filament length	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	6.69e-05	180	49	5	GO:0030832
GeneOntologyBiologicalProcess	actin filament polymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	8.64e-05	190	49	5	GO:0030041
GeneOntologyBiologicalProcess	negative regulation of cytoskeleton organization	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	9.53e-05	194	49	5	GO:0051494
GeneOntologyBiologicalProcess	negative regulation of supramolecular fiber organization	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	1.02e-04	197	49	5	GO:1902904
GeneOntologyBiologicalProcess	bradykinin catabolic process	XPNPEP1 CPN1	1.15e-04	7	49	2	GO:0010815
GeneOntologyBiologicalProcess	regulation of protein-containing complex assembly	SPTBN5 PPP2R5B SPTAN1 SPTBN2 BAX TRIOBP FCHSD1	1.46e-04	489	49	7	GO:0043254
GeneOntologyBiologicalProcess	actin polymerization or depolymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	1.79e-04	222	49	5	GO:0008154
GeneOntologyBiologicalProcess	regulation of protein polymerization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	2.15e-04	231	49	5	GO:0032271
GeneOntologyBiologicalProcess	regulation of cellular component biogenesis	SPTBN5 DLG5 PPP2R5B TBC1D10A SPTAN1 SPTBN2 BAX TRIOBP EPS8L3 FCHSD1	4.08e-04	1189	49	10	GO:0044087
GeneOntologyBiologicalProcess	regulation of supramolecular fiber organization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1 WDR47	5.72e-04	438	49	6	GO:1902903
GeneOntologyBiologicalProcess	protein-containing complex disassembly	SPTBN5 SPTAN1 SPTBN2 TRIOBP WDR47	6.20e-04	291	49	5	GO:0032984
GeneOntologyBiologicalProcess	regulation of actin filament organization	SPTBN5 SPTAN1 SPTBN2 TRIOBP FCHSD1	7.11e-04	300	49	5	GO:0110053
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex assembly	SPTBN5 SPTAN1 SPTBN2 TRIOBP	7.55e-04	173	49	4	GO:0031333
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	DNHD1 TBC1D10A FGD2 CEP250 RP1L1 HYLS1 EPS8L3	9.70e-04	670	49	7	GO:0120031
GeneOntologyCellularComponent	spectrin	SPTBN5 SPTAN1 SPTBN2	9.45e-07	9	48	3	GO:0008091
GeneOntologyCellularComponent	microtubule associated complex	SPTBN5 DNHD1 KLC2 KLC4 KIFC2	3.34e-05	161	48	5	GO:0005875
GeneOntologyCellularComponent	cortical actin cytoskeleton	SPTBN5 SPTAN1 SPTBN2 FCHSD1	6.15e-05	93	48	4	GO:0030864
GeneOntologyCellularComponent	kinesin complex	KLC2 KLC4 KIFC2	1.94e-04	49	48	3	GO:0005871
GeneOntologyCellularComponent	cortical cytoskeleton	SPTBN5 SPTAN1 SPTBN2 FCHSD1	2.18e-04	129	48	4	GO:0030863
GeneOntologyCellularComponent	paranodal junction	SPTAN1 SPTBN2	2.80e-04	11	48	2	GO:0033010
GeneOntologyCellularComponent	cuticular plate	SPTAN1 FCHSD1	3.96e-04	13	48	2	GO:0032437
GeneOntologyCellularComponent	cilium	SPTBN5 DNHD1 DLG5 TCP11X1 CEP250 RP1L1 KLC2 HYLS1	9.21e-04	898	48	8	GO:0005929
GeneOntologyCellularComponent	non-motile cilium	SPTBN5 CEP250 RP1L1 HYLS1	1.06e-03	196	48	4	GO:0097730
GeneOntologyCellularComponent	photoreceptor outer segment	SPTBN5 CEP250 RP1L1	2.12e-03	111	48	3	GO:0001750
Domain	GOLGA6L	GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA6L4	7.37e-10	6	51	4	IPR026737
Domain	GOLGA2L5	GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA6L4	1.47e-07	18	51	4	PF15070
Domain	Golgin_A	GOLGA6L10 GOLGA6L19 GOLGA6L9 GOLGA6L4	1.47e-07	18	51	4	IPR024858
Domain	Spectrin_repeat	SPTBN5 SPTAN1 SPTBN2 PLEC	1.11e-06	29	51	4	IPR002017
Domain	Spectrin/alpha-actinin	SPTBN5 SPTAN1 SPTBN2 PLEC	1.68e-06	32	51	4	IPR018159
Domain	SPEC	SPTBN5 SPTAN1 SPTBN2 PLEC	1.68e-06	32	51	4	SM00150
Domain	Kinesin_light_repeat	KLC2 KLC4	2.19e-05	3	51	2	IPR015792
Domain	KINESIN_LIGHT	KLC2 KLC4	2.19e-05	3	51	2	PS01160
Domain	Actinin_actin-bd_CS	SPTBN5 SPTBN2 PLEC	3.27e-05	23	51	3	IPR001589
Domain	Spectrin	SPTBN5 SPTAN1 SPTBN2	3.27e-05	23	51	3	PF00435
Domain	ACTININ_2	SPTBN5 SPTBN2 PLEC	3.27e-05	23	51	3	PS00020
Domain	ACTININ_1	SPTBN5 SPTBN2 PLEC	3.27e-05	23	51	3	PS00019
Domain	Kinesin_light	KLC2 KLC4	4.37e-05	4	51	2	IPR002151
Domain	Rab5-bind	KLC2 KLC4	1.09e-04	6	51	2	PF09311
Domain	Rabaptin_Rab5-bd_dom	KLC2 KLC4	1.09e-04	6	51	2	IPR015390
Domain	TPR_10	KLC2 KLC4	1.09e-04	6	51	2	PF13374
Domain	PH_dom-spectrin-type	SPTBN5 SPTBN2	2.60e-04	9	51	2	IPR001605
Domain	SH3	DLG5 MYO15B SPTAN1 EPS8L3 FCHSD1	3.01e-04	216	51	5	SM00326
Domain	SH3	DLG5 MYO15B SPTAN1 EPS8L3 FCHSD1	3.01e-04	216	51	5	PS50002
Domain	Retinoid-X_rcpt/HNF4	RXRB RXRG	3.24e-04	10	51	2	IPR000003
Domain	SH3_domain	DLG5 MYO15B SPTAN1 EPS8L3 FCHSD1	3.28e-04	220	51	5	IPR001452
Domain	PH	SPTBN5 RASA2 FGD2 SPTBN2 TRIOBP	3.94e-04	229	51	5	PF00169
Domain	CH	SPTBN5 SPTBN2 PLEC	7.44e-04	65	51	3	SM00033
Domain	CH	SPTBN5 SPTBN2 PLEC	9.23e-04	70	51	3	PF00307
Domain	PH	SPTBN5 RASA2 FGD2 SPTBN2 TRIOBP	9.46e-04	278	51	5	SM00233
Domain	PH_DOMAIN	SPTBN5 RASA2 FGD2 SPTBN2 TRIOBP	9.62e-04	279	51	5	PS50003
Domain	-	SPTBN5 SPTBN2 PLEC	9.62e-04	71	51	3	1.10.418.10
Domain	PH_domain	SPTBN5 RASA2 FGD2 SPTBN2 TRIOBP	9.77e-04	280	51	5	IPR001849
Domain	PH_dom-like	SPTBN5 RASA2 FGD2 SPTBN2 TRIOBP EPS8L3	1.03e-03	426	51	6	IPR011993
Domain	CH	SPTBN5 SPTBN2 PLEC	1.04e-03	73	51	3	PS50021
Domain	CH-domain	SPTBN5 SPTBN2 PLEC	1.13e-03	75	51	3	IPR001715
Domain	-	SPTBN5 RASA2 FGD2 SPTBN2 TRIOBP	4.18e-03	391	51	5	2.30.29.30
Domain	zf-C4	RXRB RXRG	7.01e-03	46	51	2	PF00105
Domain	Znf_hrmn_rcpt	RXRB RXRG	7.01e-03	46	51	2	IPR001628
Domain	Nuclear_hrmn_rcpt	RXRB RXRG	7.01e-03	46	51	2	IPR001723
Domain	NUCLEAR_REC_DBD_2	RXRB RXRG	7.01e-03	46	51	2	PS51030
Domain	NUCLEAR_REC_DBD_1	RXRB RXRG	7.01e-03	46	51	2	PS00031
Domain	ZnF_C4	RXRB RXRG	7.01e-03	46	51	2	SM00399
Domain	-	RXRB RXRG	7.31e-03	47	51	2	1.10.565.10
Domain	HOLI	RXRB RXRG	7.61e-03	48	51	2	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	RXRB RXRG	7.61e-03	48	51	2	IPR000536
Domain	Hormone_recep	RXRB RXRG	7.61e-03	48	51	2	PF00104
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTAN1 SPTBN2	1.66e-06	10	35	3	MM15112
Pathway	PID_RXR_VDR_PATHWAY	FAM120B RXRB RXRG	3.51e-05	26	35	3	M162
Pathway	KEGG_MEDICUS_VARIANT_PAX8_PPARG_FUSION_TO_PPARG_MEDIATED_TRANSCRIPTION	RXRB RXRG	5.96e-05	5	35	2	M49023
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTAN1 SPTBN2	6.01e-05	31	35	3	M877
Pathway	WP_VITAMIN_A1_AND_A5X_PATHWAYS	RXRB RXRG	8.93e-05	6	35	2	M48097
Pathway	WP_SMALL_CELL_LUNG_CANCER	BAX LAMC3 RXRB RXRG	8.99e-05	96	35	4	M39834
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	SPTBN5 SPTAN1 SPTBN2	1.11e-04	38	35	3	MM14969
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	SPTBN5 PPP2R5B RASA2 SPTAN1 SPTBN2 DUSP6	1.17e-04	318	35	6	MM15278
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	SPTBN5 PPP2R5B RASA2 SPTAN1 SPTBN2 DUSP6	1.37e-04	327	35	6	M27565
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMC3 RXRB RXRG	1.98e-04	46	35	3	M239
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_ANTEROGRADE_AXONAL_TRANSPORT	KLC2 KLC4	2.13e-04	9	35	2	M47699
Pathway	KEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY	RXRB RXRG	2.13e-04	9	35	2	M47629
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_KTN1	KLC2 KLC4	3.25e-04	11	35	2	M27490
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_KTN1	KLC2 KLC4	3.25e-04	11	35	2	MM15218
Pathway	REACTOME_KINESINS	KLC2 KLC4 KIFC2	3.74e-04	57	35	3	MM15714
Pathway	REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS	SPTAN1 PLEC	3.89e-04	12	35	2	MM14908
Pathway	REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS	SPTAN1 PLEC	3.89e-04	12	35	2	M3634
Pathway	REACTOME_KINESINS	KLC2 KLC4 KIFC2	4.57e-04	61	35	3	M977
Pathway	KEGG_MEDICUS_VARIANT_OLIGOMERIC_CONFORMATION_PRPC_TO_ANTEROGRADE_AXONAL_TRANSPORT	KLC2 KLC4	4.59e-04	13	35	2	M47763
Pathway	REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH	SPTBN5 SPTAN1 SPTBN2	5.03e-04	63	35	3	M11187
Pathway	REACTOME_L1CAM_INTERACTIONS	SPTBN5 SPTAN1 SPTBN2	6.29e-04	68	35	3	MM14968
Pathway	WP_NONSMALL_CELL_LUNG_CANCER	BAX RXRB RXRG	7.44e-04	72	35	3	M39738
Pathway	REACTOME_MEMBRANE_TRAFFICKING	SPTBN5 TBC1D10A SPTAN1 SPTBN2 KLC2 KLC4 KIFC2	7.75e-04	630	35	7	M11480
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	SPTBN5 TBC1D10A SPTAN1 SPTBN2 KLC2 KLC4 KIFC2	8.91e-04	645	35	7	MM15232
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMC3 RXRB RXRG	1.16e-03	84	35	3	M3228
Pathway	KEGG_MEDICUS_REFERENCE_ANTEROGRADE_AXONAL_TRANSPORT	KLC2 KLC4	1.60e-03	24	35	2	M47671
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT	KLC2 KLC4	1.73e-03	25	35	2	M47775
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SNCA_TO_ANTEROGRADE_AXONAL_TRANSPORT	KLC2 KLC4	1.73e-03	25	35	2	M47710
Pathway	REACTOME_VESICLE_MEDIATED_TRANSPORT	SPTBN5 TBC1D10A SPTAN1 SPTBN2 KLC2 KLC4 KIFC2	1.76e-03	725	35	7	M27507
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	KLC2 KLC4 KIFC2	1.81e-03	98	35	3	MM15352
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_ANTEROGRADE_AXONAL_TRANSPORT	KLC2 KLC4	1.87e-03	26	35	2	M47672
Pathway	REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	KLC2 KLC4 KIFC2	1.92e-03	100	35	3	M27650
Pathway	REACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT	SPTBN5 SPTAN1 SPTBN2	2.03e-03	102	35	3	M27648
Pathway	KEGG_THYROID_CANCER	RXRB RXRG	2.33e-03	29	35	2	M523
Pathway	REACTOME_APOPTOSIS	SPTAN1 BAX PLEC	2.39e-03	108	35	3	MM14471
Pathway	PID_RETINOIC_ACID_PATHWAY	RXRB RXRG	2.49e-03	30	35	2	M207
Pathway	REACTOME_COPI_MEDIATED_ANTEROGRADE_TRANSPORT	SPTBN5 SPTAN1 SPTBN2	2.52e-03	110	35	3	MM15350
Pathway	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	SPTBN2 KLC2 KLC4	2.93e-03	116	35	3	MM14855
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	KLC2 KLC4 KIFC2	2.93e-03	116	35	3	MM15715
Pathway	REACTOME_L1CAM_INTERACTIONS	SPTBN5 SPTAN1 SPTBN2	3.30e-03	121	35	3	M872
Pathway	KEGG_MEDICUS_REFERENCE_ARL8_REGULATED_MICROTUBULE_PLUS_END_DIRECTED_TRANSPORT	KLC2 KLC4	3.38e-03	35	35	2	M47774
Pathway	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	SPTBN2 KLC2 KLC4	3.70e-03	126	35	3	M705
Pathway	REACTOME_RHOV_GTPASE_CYCLE	DLG5 SPTAN1	3.78e-03	37	35	2	M41819
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	SPTAN1 PLEC	3.78e-03	37	35	2	MM14488
Pathway	REACTOME_RHOV_GTPASE_CYCLE	DLG5 SPTAN1	3.78e-03	37	35	2	MM15610
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	SPTAN1 PLEC	3.98e-03	38	35	2	M495
Pathway	WP_NUCLEAR_RECEPTORS	RXRB RXRG	3.98e-03	38	35	2	M39657
Pathway	WP_NUCLEAR_RECEPTORS	RXRB RXRG	3.98e-03	38	35	2	MM15865
Pathway	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	KLC2 KLC4 KIFC2	4.13e-03	131	35	3	MM15497
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DLG5 SPTAN1	4.19e-03	39	35	2	MM15607
Pathway	REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	KLC2 KLC4 KIFC2	4.40e-03	134	35	3	M27751
Pathway	REACTOME_RHOU_GTPASE_CYCLE	DLG5 SPTAN1	4.40e-03	40	35	2	M41816
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DLG5 PPP2R5B FGD2 SPTAN1 KLC2 KLC4	4.82e-03	649	35	6	MM15690
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	PPP2R5B DUSP6	4.84e-03	42	35	2	MM15274
Pathway	WP_VITAMIN_A_AND_CAROTENOID_METABOLISM	RXRB RXRG	5.07e-03	43	35	2	M39554
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	PPP2R5B DUSP6	5.07e-03	43	35	2	M27560
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RXRB RXRG	5.07e-03	43	35	2	M27443
Pathway	REACTOME_PROGRAMMED_CELL_DEATH	SPTAN1 BAX PLEC	5.17e-03	142	35	3	MM15178
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTBN5 SPTAN1 SPTBN2	9.45e-07	13	53	3	18796539
Pubmed	Mapping of the mouse Rxr loci encoding nuclear retinoid X receptors RXR alpha, RXR beta, and RXR gamma.	SPTAN1 RXRB RXRG	9.45e-07	13	53	3	1358808
Pubmed	Suppression of retinoic acid receptor beta in non-small-cell lung cancer in vivo: implications for lung cancer development.	RXRB RXRG	2.28e-06	2	53	2	9150186
Pubmed	Retinoid x receptor gamma control of affective behaviors involves dopaminergic signaling in mice.	RXRB RXRG	2.28e-06	2	53	2	20620876
Pubmed	Characterization of a new beta-spectrin gene which is predominantly expressed in brain.	SPTAN1 SPTBN2	2.28e-06	2	53	2	9675416
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTBN5 SPTAN1 SPTBN2	2.68e-06	18	53	3	12119179
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	KDM5B DLG5 FAM120B SPTAN1 SPTBN2 TRIOBP PLEC CPSF2 NDUFS2 RRP1	4.71e-06	1082	53	10	38697112
Pubmed	Retinoid X receptors: X-ploring their (patho)physiological functions.	RXRB RXRG	6.83e-06	3	53	2	15608692
Pubmed	Chromosomal localization of the human retinoid X receptors.	RXRB RXRG	6.83e-06	3	53	2	8034312
Pubmed	Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition.	RXRB RXRG	6.83e-06	3	53	2	7831303
Pubmed	Retinoid receptors trigger neuritogenesis in retinal degenerations.	RXRB RXRG	6.83e-06	3	53	2	21940995
Pubmed	The role of retinoid X receptor messenger RNA expression in curatively resected non-small cell lung cancer.	RXRB RXRG	6.83e-06	3	53	2	11839661
Pubmed	Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.	RXRB RXRG	6.83e-06	3	53	2	1312497
Pubmed	Detection of retinoid X receptors using specific monoclonal and polyclonal antibodies.	RXRB RXRG	6.83e-06	3	53	2	7980510
Pubmed	Immunohistochemical detection of the retinoid X receptors alpha, beta, and gamma in human prostate.	RXRB RXRG	6.83e-06	3	53	2	12514092
Pubmed	An essential role for retinoid receptors RARbeta and RXRgamma in long-term potentiation and depression.	RXRB RXRG	6.83e-06	3	53	2	9883728
Pubmed	Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects.	RXRB RXRG	6.83e-06	3	53	2	11053444
Pubmed	Impaired locomotion and dopamine signaling in retinoid receptor mutant mice.	RXRB RXRG	6.83e-06	3	53	2	9452386
Pubmed	RXR gamma null mice are apparently normal and compound RXR alpha +/-/RXR beta -/-/RXR gamma -/- mutant mice are viable.	RXRB RXRG	6.83e-06	3	53	2	8799145
Pubmed	NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.	SPTAN1 SPTBN2 PLEC	7.51e-06	25	53	3	30309841
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SPTBN5 DNHD1 DLG5 SPTAN1 PLEC	9.91e-06	187	53	5	26460568
Pubmed	Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.	RXRB RXRG	1.36e-05	4	53	2	9804293
Pubmed	Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.	RXRB RXRG	1.36e-05	4	53	2	1310259
Pubmed	Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice.	RXRB RXRG	1.36e-05	4	53	2	10079186
Pubmed	Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.	RXRB RXRG	1.36e-05	4	53	2	26355550
Pubmed	Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.	RXRB RXRG	1.36e-05	4	53	2	19686701
Pubmed	Loss of retinoid X receptor gamma subunit impairs group 1 mGluR mediated electrophysiological responses and group 1 mGluR dependent behaviors.	RXRB RXRG	1.36e-05	4	53	2	33692389
Pubmed	The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.	SPTBN5 SPTAN1 SPTBN2	1.61e-05	32	53	3	23704327
Pubmed	Retinoic acid signaling is necessary for the development of the organ of Corti.	RXRB RXRG	2.27e-05	5	53	2	10452855
Pubmed	Developmental expression of murine retinoid X receptor (RXR) genes.	RXRB RXRG	2.27e-05	5	53	2	8199055
Pubmed	Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 and 2 and to the 240-kilodalton subunit of spectrin.	SPTAN1 PLEC	2.27e-05	5	53	2	3027087
Pubmed	Peroxisome proliferator-activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma.	RXRB RXRG	3.40e-05	6	53	2	22205725
Pubmed	The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development.	RXRB RXRG	3.40e-05	6	53	2	9806918
Pubmed	Systematic immunolocalization of retinoid receptors in developing and adult mouse eyes.	RXRB RXRG	3.40e-05	6	53	2	11328745
Pubmed	ST3GAL1 and βII-spectrin pathways control CAR T cell migration to target tumors.	SPTAN1 SPTBN2	3.40e-05	6	53	2	37069398
Pubmed	TGIF inhibits retinoid signaling.	RXRB RXRG	3.40e-05	6	53	2	16428452
Pubmed	Cutting edge: integration of human T lymphocyte cytoskeleton by the cytolinker plectin.	SPTAN1 PLEC	3.40e-05	6	53	2	11441066
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	SPTAN1 SPTBN2	3.40e-05	6	53	2	23728480
Pubmed	A genetic dissection of the retinoid signalling pathway in the mouse.	RXRB RXRG	3.40e-05	6	53	2	10604193
Pubmed	Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.	RXRB RXRG	3.40e-05	6	53	2	7947324
Pubmed	The isolation and characterization of purified heterocomplexes of recombinant retinoic acid receptor and retinoid X receptor ligand binding domains.	RXRB RXRG	3.40e-05	6	53	2	9153406
Pubmed	Spatial distributions of retinoic acid receptor gene transcripts in the prenatal mouse inner ear.	RXRB RXRG	3.40e-05	6	53	2	9548551
Pubmed	Functional specificity of the two retinoic acid receptor RAR and RXR families in myogenesis.	RXRB RXRG	3.40e-05	6	53	2	9464546
Pubmed	Effect of retinoid status on the messenger ribonucleic acid expression of nuclear retinoid receptors alpha, beta, and gamma, and retinoid X receptors alpha, beta, and gamma in the mouse testis.	RXRB RXRG	3.40e-05	6	53	2	9075714
Pubmed	Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.	RXRB RXRG	3.40e-05	6	53	2	20557428
Pubmed	RAR and RXR selective ligands cooperatively induce apoptosis and neuronal differentiation in P19 embryonal carcinoma cells.	RXRB RXRG	3.40e-05	6	53	2	8801169
Pubmed	A decade of molecular biology of retinoic acid receptors.	RXRB RXRG	3.40e-05	6	53	2	8801176
Pubmed	Spectrins and ankyrinB constitute a specialized paranodal cytoskeleton.	SPTAN1 SPTBN2	3.40e-05	6	53	2	16687515
Pubmed	Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors.	RXRB RXRG	4.76e-05	7	53	2	17195188
Pubmed	Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes.	RXRB RXRG	4.76e-05	7	53	2	9428411
Pubmed	Differential contributions of AF-1 and AF-2 activities to the developmental functions of RXR alpha.	RXRB RXRG	4.76e-05	7	53	2	11493527
Pubmed	The structure of the nuclear hormone receptors.	RXRB RXRG	4.76e-05	7	53	2	10406480
Pubmed	Analysis of the factors involved in the retinoic acid-induced differentiation of a retinoid-hypersensitive embryonal carcinoma cell mutant.	RXRB RXRG	4.76e-05	7	53	2	8299717
Pubmed	Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.	RXRB RXRG	4.76e-05	7	53	2	12360493
Pubmed	Structural variants in the retinoid receptor genes in patients with schizophrenia and other psychiatric diseases.	RXRB RXRG	4.76e-05	7	53	2	15635645
Pubmed	Creatine kinase (CK) in skeletal muscle energy metabolism: a study of mouse mutants with graded reduction in muscle CK expression.	RXRB RXRG	4.76e-05	7	53	2	8090775
Pubmed	Dorsal and ventral rentinoic territories defined by retinoic acid synthesis, break-down and nuclear receptor expression.	RXRB RXRG	6.34e-05	8	53	2	10490294
Pubmed	Expression of nuclear retinoic acid receptors during mouse odontogenesis.	RXRB RXRG	6.34e-05	8	53	2	7988794
Pubmed	RUSC2 and WDR47 oppositely regulate kinesin-1-dependent distribution of ATG9A to the cell periphery.	KLC2 WDR47	6.34e-05	8	53	2	34432492
Pubmed	Retinoids and adipose tissues: metabolism, cell differentiation and gene expression.	RXRB RXRG	6.34e-05	8	53	2	10094571
Pubmed	Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.	RXRB RXRG	6.34e-05	8	53	2	16043864
Pubmed	Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells.	RXRB RXRG	6.34e-05	8	53	2	17124491
Pubmed	LMO7 deficiency reveals the significance of the cuticular plate for hearing function.	SPTAN1 TRIOBP	6.34e-05	8	53	2	30850599
Pubmed	Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones.	RXRB RXRG	8.15e-05	9	53	2	8650181
Pubmed	A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells.	RXRB RXRG	8.15e-05	9	53	2	7823919
Pubmed	Analysis of the DNA sequence and duplication history of human chromosome 15.	GOLGA6L10 GOLGA6L19 GOLGA6L4	8.75e-05	56	53	3	16572171
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	SPTAN1 SPTBN2	1.02e-04	10	53	2	22159418
Pubmed	Enhancer activation requires trans-recruitment of a mega transcription factor complex.	RXRB RXRG	1.02e-04	10	53	2	25303530
Pubmed	Physical mapping of the retinoid X receptor B gene in mouse and human.	RXRB RXRG	1.24e-04	11	53	2	7806300
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTAN1 SPTBN2	1.24e-04	11	53	2	17607528
Pubmed	Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter.	RXRB RXRG	1.24e-04	11	53	2	29093497
Pubmed	A proteome-scale map of the SARS-CoV-2-human contactome.	CEP250 KLC2 KLC4 GOLGA6L9	1.43e-04	173	53	4	36217029
Pubmed	Differential expression of transcripts encoding retinoid binding proteins and retinoic acid receptors during placentation of the mouse.	RXRB RXRG	1.49e-04	12	53	2	9022057
Pubmed	Cholesterol and cholesterol plus DHA diet-induced gene expression and fatty acid changes in mouse eye and brain.	RXRB RXRG	1.49e-04	12	53	2	15589691
Pubmed	The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.	KLC2 KLC4	1.49e-04	12	53	2	16018997
Pubmed	Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.	RXRB RXRG	1.49e-04	12	53	2	26427057
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP2R5B ATAD5 SPTAN1 SPTBN2 DUSP6 BAX TRIOBP CPSF2	1.77e-04	1049	53	8	27880917
Pubmed	Retinoic acid regulates murine enteric nervous system precursor proliferation, enhances neuronal precursor differentiation, and reduces neurite growth in vitro.	RXRB RXRG	2.05e-04	14	53	2	18561907
Pubmed	Retinoic acid induces prostatic bud formation.	RXRB RXRG	2.05e-04	14	53	2	18393306
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	RXRB RXRG	2.05e-04	14	53	2	21923909
Pubmed	Modular patterning of structure and function of the striatum by retinoid receptor signaling.	RXRB RXRG	2.05e-04	14	53	2	18443282
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DLG5 TBC1D10A SPTAN1 SPTBN2 KLC2 PLEC	2.15e-04	565	53	6	25468996
Pubmed	Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.	RXRB RXRG	2.36e-04	15	53	2	19448158
Pubmed	Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta.	RXRB RXRG	2.70e-04	16	53	2	25577283
Pubmed	Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins.	SPTAN1 PLEC	2.70e-04	16	53	2	16944923
Pubmed	External genitalia formation: role of fibroblast growth factor, retinoic acid signaling, and distal urethral epithelium.	RXRB RXRG	2.70e-04	16	53	2	11795391
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	SPTAN1 KLC2 TSEN54 XPNPEP1 HSF4 KIFC2 NDUFS2 RXRG	2.83e-04	1124	53	8	21900206
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	SPTAN1 KLC2 PLEC NDUFS2	3.00e-04	210	53	4	26217791
Pubmed	Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.	RXRB RXRG	3.05e-04	17	53	2	28291835
Pubmed	The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina.	BAX RXRG	3.05e-04	17	53	2	25501893
Pubmed	Atoh7-independent specification of retinal ganglion cell identity.	BAX RXRG	3.05e-04	17	53	2	33712461
Pubmed	A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.	CEP250 KLC2 KLC4	3.24e-04	87	53	3	17979178
Pubmed	The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.	ATAD5 CEP250 CPSF2	3.69e-04	91	53	3	20546612
Pubmed	Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough.	XPNPEP1 CPN1	3.83e-04	19	53	2	21052031
Pubmed	Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning.	RXRB RXRG	4.25e-04	20	53	2	19605690
Pubmed	Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid.	RXRB RXRG	5.16e-04	22	53	2	10753524
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	TBC1D10A USHBP1 CEP250 KLC2 LAMC3 TIMELESS XPNPEP1 WDR47	5.49e-04	1242	53	8	30973865
Pubmed	Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.	RXRB RXRG	5.65e-04	23	53	2	19737349
Pubmed	Chromosomal localization of the proteasome Z subunit gene reveals an ancient chromosomal duplication involving the major histocompatibility complex.	SPTAN1 RXRB	5.65e-04	23	53	2	8799160
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTBN5 SPTAN1	6.68e-04	25	53	2	8493579
Cytoband	15q25.2	GOLGA6L10 GOLGA6L9 GOLGA6L4	1.64e-05	43	52	3	15q25.2
Cytoband	Ensembl 112 genes in cytogenetic band chr15q25	GOLGA6L10 GOLGA6L9 GOLGA6L4	8.10e-04	160	52	3	chr15q25
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	SIKE1 EPS8L3 WDR47	1.79e-03	211	52	3	chr1p13
Cytoband	Ensembl 112 genes in cytogenetic band chr6p21	FGD2 KLC4 SAPCD1 RXRB	2.54e-03	503	52	4	chr6p21
Cytoband	1p13.3	EPS8L3 WDR47	2.81e-03	69	52	2	1p13.3
Cytoband	17q25.1	MYO15B TSEN54	3.85e-03	81	52	2	17q25.1
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTAN1 SPTBN2	1.59e-07	7	31	3	1113
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASA2 FGD2 SPTBN2 TRIOBP	4.05e-04	206	31	4	682
GeneFamily	Nuclear hormone receptors	RXRB RXRG	3.18e-03	49	31	2	71
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	KLC2 KLC4	1.65e-02	115	31	2	769
Computational	Neighborhood of PDPK1	PNMT KHNYN HSF4 RXRB	2.35e-05	74	25	4	MORF_PDPK1
Computational	Neighborhood of CNTN1	PNMT KHNYN HSF4 RXRB	1.04e-04	108	25	4	MORF_CNTN1
Computational	Neighborhood of PTPN9	KHNYN HSF4 RXRB	3.66e-04	61	25	3	MORF_PTPN9
Computational	Neighborhood of RBM8A	PNMT KHNYN HSF4	9.68e-04	85	25	3	MORF_RBM8A
Drug	ADPribulose	SPTBN5 SPTAN1 SPTBN2	2.81e-06	13	50	3	CID000197570
Drug	Cd2665	BAX RXRB RXRG	2.81e-06	13	50	3	CID000216241
Drug	PRODAN	SPTBN5 SPTAN1 SPTBN2	4.45e-06	15	50	3	CID000028127
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; PC3; HT_HG-U133A	PPP2R5B ATAD5 SPTAN1 KHNYN SPTBN2 BAX	4.91e-06	200	50	6	5043_DN
Drug	maleimide	SPTBN5 SPTAN1 SPTBN2 TIMELESS XPNPEP1	1.01e-05	131	50	5	CID000010935
Drug	Bexarotene	RXRB RXRG	1.42e-05	3	50	2	DB00307
Drug	2-hydroxyphytanic acid	RXRB RXRG	1.42e-05	3	50	2	ctd:C002585
Drug	AC1O5SBP	RXRB RXRG	1.42e-05	3	50	2	CID006439746
Drug	retinamide	BAX TGM7 RXRB RXRG	1.60e-05	69	50	4	CID005370221
Drug	AGN 190727	RXRB RXRG	2.83e-05	4	50	2	CID006439768
Drug	phenylhydrazine	SPTBN5 SPTAN1 SPTBN2 PLEC	3.17e-05	82	50	4	CID000007516
Drug	plakin	SPTBN5 SPTAN1 SPTBN2 PLEC	3.17e-05	82	50	4	CID000018752
Drug	SR-12813	PLEC RXRB RXRG	3.50e-05	29	50	3	CID000446313
Drug	dimethyl adipimidate	SPTBN5 SPTAN1 SPTBN2	3.88e-05	30	50	3	CID000025738
Drug	7-methoxycitronellal	RXRB RXRG	4.71e-05	5	50	2	CID000019223
Drug	7-methoxycitronellic acid	RXRB RXRG	4.71e-05	5	50	2	CID000171516
Drug	13,14-dihydroretinol	RXRB RXRG	4.71e-05	5	50	2	CID000446798
Drug	Retinoids	BAX RXRB RXRG	5.68e-05	34	50	3	ctd:D012176
Drug	Alitretinoin	RXRB RXRG	7.05e-05	6	50	2	DB00523
Drug	Adapalene	RXRB RXRG	7.05e-05	6	50	2	DB00210
Drug	triphenyltin hydroxide	RXRB RXRG	7.05e-05	6	50	2	ctd:C007567
Drug	Etretinate	RXRB RXRG	7.05e-05	6	50	2	DB00926
Drug	Pilocarpine nitrate [148-72-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A	DLG5 PPP2R5B SPTAN1 TIMELESS PLEC	7.12e-05	197	50	5	3300_DN
Drug	Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A	PPP2R5B SPTBN2 LAMC3 TIMELESS HSF4	7.12e-05	197	50	5	3187_UP
Drug	Cortisone [53-06-5]; Down 200; 11uM; MCF7; HT_HG-U133A	CEP250 KHNYN KLC2 TRIOBP PLEC	7.29e-05	198	50	5	7416_DN
Drug	Melatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A	SPTBN5 DLG5 ATAD5 SPTAN1 PLEC	7.29e-05	198	50	5	5393_DN
Drug	Ro 41-5253	BAX RXRB RXRG	7.35e-05	37	50	3	CID005312120
Drug	Tocainide hydrochloride; Up 200; 17.4uM; HL60; HT_HG-U133A	PPP2R5B SPTAN1 CEP250 TIMELESS PLEC	7.47e-05	199	50	5	2931_UP
Drug	Lasalocid sodium salt [25999-20-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A	PPP2R5B CEP250 SPTBN2 KLC2 TIMELESS	7.47e-05	199	50	5	3360_DN
Drug	tazarotene	BAX RXRB RXRG	9.30e-05	40	50	3	CID000005381
Drug	Acitretin	RXRB RXRG	9.86e-05	7	50	2	DB00459
Drug	AGN 191659	RXRB RXRG	9.86e-05	7	50	2	CID006366726
Drug	AGN 190121	RXRB RXRG	9.86e-05	7	50	2	CID006441236
Drug	acyclic retinoid	BAX RXRB RXRG	1.00e-04	41	50	3	CID006437836
Drug	HX 600	RXRB RXRG	1.31e-04	8	50	2	ctd:C104181
Drug	TTNN	RXRB RXRG	1.31e-04	8	50	2	CID000135754
Drug	Tretinoin	RXRB RXRG	1.31e-04	8	50	2	DB00755
Drug	AC1O5JP6	RXRB RXRG	1.31e-04	8	50	2	CID006435379
Drug	AC1L1HRY	BAX RXRB RXRG	1.33e-04	45	50	3	CID000004265
Drug	2-nitro-5-thiocyanobenzoic acid	SPTBN5 SPTAN1 SPTBN2	1.61e-04	48	50	3	CID000092266
Drug	diethyl phthalate	BAX RXRB RXRG	1.61e-04	48	50	3	ctd:C007379
Drug	tetrathionate	SPTBN5 SPTAN1 SPTBN2	1.71e-04	49	50	3	CID000026259
Drug	cyclopentanol	CPN1 OGG1	2.10e-04	10	50	2	CID000007298
Drug	HX 630	RXRB RXRG	2.10e-04	10	50	2	ctd:C422175
Drug	mafosfamide	BAX OGG1	2.10e-04	10	50	2	ctd:C048341
Drug	diazepinylbenzoic acid	RXRB RXRG	2.10e-04	10	50	2	ctd:C438269
Disease	Alzheimer's disease 1 (implicated_via_orthology)	KLC2 KLC4	5.64e-05	7	49	2	DOID:0080348 (implicated_via_orthology)
Disease	Brain Diseases	LAMC3 OGG1	7.91e-04	25	49	2	C0006111
Disease	cataract (is_implicated_in)	HSF4 OGG1	8.56e-04	26	49	2	DOID:83 (is_implicated_in)
Disease	Encephalopathies	LAMC3 OGG1	9.23e-04	27	49	2	C0085584

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLLEQLRWERAELQA	USHBP1	526	Q8N6Y0
ERQELWQGLEELRLR	PPP2R5B	456	Q15173
EEVRNLLLEEIRWSN	ATAD5	941	Q96QE3
GRVLELAQLLDQIWR	CPSF2	241	Q9P2I0
GLGCEELQWLLQREQ	DNHD1	3696	Q96M86
ELEQEREQLRLQLWE	BICDL1	356	Q6ZP65
LEIRIDLWNNGNLVQ	RASA2	251	Q15283
NQWLRDELAGTQQRL	KLC4	116	Q9NSK0
QDLILQVRDGWLQLL	EPS8L3	66	Q8TE67
DGRLRVNDWLLRIND	DLG5	666	Q8TDM6
LWQQETLQELERLRE	GOLGA6L3	411	A6NEY3
ERLRQQDERLWQQET	GOLGA6L4	421	A6NEF3
WQQETLQELERLREL	GOLGA6L4	431	A6NEF3
LLEQERLRQQDERLW	GOLGA6L9	281	A6NEM1
LEQERLRQQDERLWQ	GOLGA6L10	366	A6NI86
ERLWQQETLRELERL	GOLGA6L10	376	A6NI86
QQDERLWQQETLREL	GOLGA6L19	401	H0YKK7
LWQQETLRELERLRE	GOLGA6L19	406	H0YKK7
RIRLEQARWLEEVQQ	KDM5B	911	Q9UGL1
RELEIQALRWAIQNG	LMNTD2	71	Q8IXW0
LEEQGGLAWLQQLRE	OGG1	216	O15527
DELEELLTNNRIWRN	NDUFS2	256	O75306
RLVQENQWLREELAG	KLC2	101	Q9H0B6
LLQEQGWQRLEELRD	MYO15B	321	Q96JP2
GWQRLEELRDQQRSQ	MYO15B	326	Q96JP2
QTWQQREADLLEDIR	FCHSD1	26	Q86WN1
GTENDQDLWDLRQRL	HYLS1	121	Q96M11
QREWLGNREALIQFL	CPN1	321	P15169
LDFLRERLLGWIQDQ	BAX	141	Q07812
RQQLEVLEQEAWRLR	CEP250	476	Q9BV73
RLRELRQQNEILWRE	HSF4	156	Q9ULV5
RLQDLWEVYQRLGLE	FGD2	296	Q7Z6J4
ERLRRQLLEVFWGQD	KHNYN	636	O15037
VQQDQLWRELLEAER	C2orf50	66	Q96LR7
AWLNEQLELGNERLL	DUSP6	21	Q16828
LQLEEDQRAWQRLEQ	KIFC2	186	Q96AC6
DQRAWQRLEQLILGQ	KIFC2	191	Q96AC6
LWLNQEPEIQVRRLD	FAM120B	681	Q96EK7
LENSLWIRQEERAEI	KRBA2	446	Q6ZNG9
EEQLERALQASLWDR	RHBDD1	271	Q8TEB9
ELWQLLAEQRVERLG	TSEN54	61	Q7Z6J9
WQNRLRNEIEEALDT	TCP11X1	126	B4DZS4
RDLQQENRELWISLE	SIKE1	81	Q9BRV8
QGWEERQIEELLELL	RRP1	136	P56182
EREQDALWQGLELLQ	SAPCD1	46	Q5SSQ6
ELQRLQQEKEWLLAE	TRIOBP	2136	Q9H2D6
DLLEEIHLWQERLQQ	SPTBN5	1146	Q9NRC6
DDQVILLRAGWNELL	RXRB	366	P28702
DFLEVNRQELGRWLQ	PNMT	101	P11086
LQLGWEERQEEDNLL	TIMELESS	141	Q9UNS1
FLRQLILDGQWDEVL	WDR47	51	O94967
QKQGRQEALEWLIRE	XPNPEP1	601	Q9NQW7
RAAELQAQWERLEAL	SPTBN2	721	O15020
LRARWGLQDNDLLDQ	RP1L1	1541	Q8IWN7
LNERWRSLQQLAEER	SPTAN1	1211	Q13813
EDQVILLRAGWNELL	RXRG	296	P48443
QDGVRANELQLRWQE	PLEC	406	Q15149
LEGLADQGLRQLWEN	nan	281	Q6ZUG5
EWGQDLQLLLRIQRV	TGM7	501	Q96PF1
LIQLRRWQETRGELQ	TBC1D10A	366	Q9BXI6
NETQWALERLRLQLG	LAMC3	1506	Q9Y6N6