Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	5.92e-07	27	123	5	GO:0033038
GeneOntologyMolecularFunction	taste receptor activity	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.69e-06	33	123	5	GO:0008527
GeneOntologyMolecularFunction	zinc ion binding	RC3H1 QTRT2 ZFAND5 NR1D1 PARP1 ZNF117 NR1I2 ZFHX4 ADAMTS9 ZFAND6 RNF216 KDM4A XAF1 ZMYM6 TOP3A TRIM51G	1.17e-04	891	123	16	GO:0008270
GeneOntologyMolecularFunction	protein tyrosine phosphatase activity	CDC14C CDC14B PTPRJ PTPRM SSH2	4.42e-04	103	123	5	GO:0004725
GeneOntologyMolecularFunction	histone H3K9me2/H3K9me3 demethylase activity	KDM4A KDM4B	5.55e-04	6	123	2	GO:0140684
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of bitter taste	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	6.27e-06	44	123	5	GO:0001580
GeneOntologyBiologicalProcess	sensory perception of bitter taste	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	9.69e-06	48	123	5	GO:0050913
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of taste	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.19e-05	50	123	5	GO:0050912
GeneOntologyBiologicalProcess	regulation of T cell receptor signaling pathway	RC3H1 DGKZ USP46 MALT1 PTPRJ	1.90e-05	55	123	5	GO:0050856
GeneOntologyBiologicalProcess	T cell receptor signaling pathway	RC3H1 DGKZ USP46 TXK MALT1 PTPRJ FYN	4.96e-05	160	123	7	GO:0050852
GeneOntologyBiologicalProcess	sensory perception of taste	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	6.17e-05	70	123	5	GO:0050909
GeneOntologyBiologicalProcess	regulation of antigen receptor-mediated signaling pathway	RC3H1 DGKZ USP46 MALT1 PTPRJ	9.74e-05	77	123	5	GO:0050854
GeneOntologyCellularComponent	motile cilium	CUL3 TPPP2 CFAP43 TEKT5 C2CD6 TAS2R45 TAS2R31 TAS2R30 TAS2R46 ATP1A4	4.50e-05	355	122	10	GO:0031514
Domain	TAS2R	TAS2R45 TAS2R31 TAS2R30 TAS2R46	2.10e-05	26	119	4	PF05296
Domain	T2R	TAS2R45 TAS2R31 TAS2R30 TAS2R46	2.10e-05	26	119	4	IPR007960
Domain	ZF_PHD_2	PHF6 BAZ1A ASXL3 KDM4A KDM4B	3.54e-04	95	119	5	PS50016
Domain	EPHD	PHF6 KDM4A KDM4B	3.56e-04	22	119	3	PS51805
Domain	ZF_PHD_1	PHF6 BAZ1A ASXL3 KDM4A KDM4B	3.72e-04	96	119	5	PS01359
Domain	TUDOR	TDRD9 KDM4A KDM4B	4.07e-04	23	119	3	PS50304
Domain	P-type_ATPase_IIC	ATP1A2 ATP1A4	5.94e-04	6	119	2	IPR005775
Domain	TUDOR	TDRD9 KDM4A KDM4B	6.60e-04	27	119	3	SM00333
Domain	ZF_A20	ZFAND5 ZFAND6	8.28e-04	7	119	2	PS51036
Domain	zf-A20	ZFAND5 ZFAND6	8.28e-04	7	119	2	PF01754
Domain	Znf_A20	ZFAND5 ZFAND6	8.28e-04	7	119	2	IPR002653
Domain	ZnF_A20	ZFAND5 ZFAND6	8.28e-04	7	119	2	SM00259
Domain	Tudor	TDRD9 KDM4A KDM4B	9.03e-04	30	119	3	IPR002999
Domain	-	ATP8B4 ATP1A2 ATP1A4	1.09e-03	32	119	3	3.40.1110.10
Domain	-	ATP8B4 ATP1A2 ATP1A4	1.09e-03	32	119	3	2.70.150.10
Domain	ZF_AN1	ZFAND5 ZFAND6	1.10e-03	8	119	2	PS51039
Domain	ZnF_AN1	ZFAND5 ZFAND6	1.10e-03	8	119	2	SM00154
Domain	-	ZFAND5 ZFAND6	1.10e-03	8	119	2	4.10.1110.10
Domain	zf-AN1	ZFAND5 ZFAND6	1.10e-03	8	119	2	PF01428
Domain	Znf_AN1	ZFAND5 ZFAND6	1.10e-03	8	119	2	IPR000058
Domain	Tyr_Pase_AS	CDC14B PTPRJ PTPRM SSH2	1.22e-03	73	119	4	IPR016130
Domain	ATPase_P-typ_cyto_domN	ATP8B4 ATP1A2 ATP1A4	1.42e-03	35	119	3	IPR023299
Domain	ATPase_P-typ_P_site	ATP8B4 ATP1A2 ATP1A4	1.54e-03	36	119	3	IPR018303
Domain	P_typ_ATPase	ATP8B4 ATP1A2 ATP1A4	1.54e-03	36	119	3	IPR001757
Domain	ATPASE_E1_E2	ATP8B4 ATP1A2 ATP1A4	1.54e-03	36	119	3	PS00154
Domain	zf-C2H2	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	1.57e-03	693	119	12	PF00096
Domain	ATPase_P-typ_transduc_dom_A	ATP8B4 ATP1A2 ATP1A4	1.67e-03	37	119	3	IPR008250
Domain	E1-E2_ATPase	ATP8B4 ATP1A2 ATP1A4	1.67e-03	37	119	3	PF00122
Domain	JmjN	KDM4A KDM4B	1.75e-03	10	119	2	SM00545
Domain	JmjN	KDM4A KDM4B	1.75e-03	10	119	2	PF02375
Domain	JMJN	KDM4A KDM4B	1.75e-03	10	119	2	PS51183
Domain	JmjN	KDM4A KDM4B	1.75e-03	10	119	2	IPR003349
Domain	TYR_PHOSPHATASE_1	CDC14B PTPRJ PTPRM SSH2	2.23e-03	86	119	4	PS00383
Domain	PTPase_domain	CDC14B PTPRJ PTPRM	2.25e-03	41	119	3	IPR000242
Domain	Y_phosphatase	CDC14B PTPRJ PTPRM	2.25e-03	41	119	3	PF00102
Domain	TYR_PHOSPHATASE_dom	CDC14B PTPRJ PTPRM SSH2	2.32e-03	87	119	4	IPR000387
Domain	TYR_PHOSPHATASE_2	CDC14B PTPRJ PTPRM SSH2	2.32e-03	87	119	4	PS50056
Domain	PHD	PHF6 BAZ1A KDM4A KDM4B	2.52e-03	89	119	4	SM00249
Domain	Mab-21	ITPRIP MAB21L1	2.55e-03	12	119	2	PF03281
Domain	Mab-21	ITPRIP MAB21L1	2.55e-03	12	119	2	SM01265
Domain	Mab-21_dom	ITPRIP MAB21L1	2.55e-03	12	119	2	IPR024810
Domain	Znf_PHD	PHF6 BAZ1A KDM4A KDM4B	2.73e-03	91	119	4	IPR001965
Domain	-	CDC14B PTPRJ PTPRM SSH2	2.84e-03	92	119	4	3.90.190.10
Domain	VitD_rcpt	NR1D1 NR1I2	3.48e-03	14	119	2	IPR000324
Domain	Prot-tyrosine_phosphatase-like	CDC14B PTPRJ PTPRM SSH2	3.70e-03	99	119	4	IPR029021
Domain	ZINC_FINGER_C2H2_2	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	3.91e-03	775	119	12	PS50157
Domain	ZINC_FINGER_C2H2_1	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	3.99e-03	777	119	12	PS00028
Domain	-	HIVEP2 ZNF652 HIVEP3 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	4.08e-03	679	119	11	3.30.160.60
Domain	ATPase_P-typ_TM_dom	ATP1A2 ATP1A4	4.56e-03	16	119	2	IPR023298
Domain	-	ATP1A2 ATP1A4	4.56e-03	16	119	2	1.20.1110.10
Domain	Znf_C2H2/integrase_DNA-bd	HIVEP2 ZNF652 HIVEP3 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	4.80e-03	694	119	11	IPR013087
Domain	Znf_C2H2-like	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	4.83e-03	796	119	12	IPR015880
Domain	ATPase_P-typ_cation-transptr_C	ATP1A2 ATP1A4	5.14e-03	17	119	2	IPR006068
Domain	Cation_ATPase_C	ATP1A2 ATP1A4	5.14e-03	17	119	2	PF00689
Domain	Znf_C2H2	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	5.28e-03	805	119	12	IPR007087
Domain	ZnF_C2H2	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 ZFHX4 GLI1 ZNF721 ZNF749 PRDM15	5.43e-03	808	119	12	SM00355
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	5.76e-03	18	119	2	PF00690
Domain	HA2	TDRD9 YTHDC2	5.76e-03	18	119	2	SM00847
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	5.76e-03	18	119	2	SM00831
Domain	HA2	TDRD9 YTHDC2	5.76e-03	18	119	2	PF04408
Domain	Helicase-assoc_dom	TDRD9 YTHDC2	5.76e-03	18	119	2	IPR007502
Domain	PTPc_motif	CDC14B PTPRJ PTPRM	6.33e-03	59	119	3	SM00404
Domain	Tyr_Pase_cat	CDC14B PTPRJ PTPRM	6.33e-03	59	119	3	IPR003595
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R45 TAS2R31 TAS2R30 TAS2R46	4.67e-05	31	92	4	MM15691
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R45 TAS2R31 TAS2R30 TAS2R46	9.51e-05	37	92	4	MM15067
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	7.21e-08	12	123	4	12379855
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.04e-07	13	123	4	15938754
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SH3TC2 ATP8B4 RC3H1 ANKRD62 ATG14 MYSM1 HIVEP3 RAB3GAP1 ZBTB39 TRPM3 ADAMTS9 SSH2	2.00e-07	493	123	12	15368895
Pubmed	A novel family of mammalian taste receptors.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	8.51e-07	21	123	4	10761934
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.04e-06	22	123	4	12734386
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.25e-06	23	123	4	20022913
Pubmed	Receptors for bitter and sweet taste.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.78e-06	25	123	4	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	2.10e-06	26	123	4	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	2.45e-06	27	123	4	12581520
Pubmed	Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	3.80e-06	30	123	4	17273929
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R45 TAS2R31 TAS2R30 TAS2R46	3.80e-06	30	123	4	12679530
Pubmed	Overexpression of CDC14B causes mitotic arrest and inhibits zygotic genome activation in mouse preimplantation embryos.	CDC14C CDC14B	1.24e-05	2	123	2	19923902
Pubmed	The Cdc14B phosphatase displays oncogenic activity mediated by the Ras-Mek signaling pathway.	CDC14C CDC14B	1.24e-05	2	123	2	21502810
Pubmed	Reader domain specificity and lysine demethylase-4 family function.	KDM4A KDM4B	1.24e-05	2	123	2	27841353
Pubmed	Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.	RC3H1 MALT1	1.24e-05	2	123	2	37988467
Pubmed	Birth and rapid subcellular adaptation of a hominoid-specific CDC14 protein.	CDC14C CDC14B	1.24e-05	2	123	2	18547142
Pubmed	Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.	HIVEP2 HIVEP3	1.24e-05	2	123	2	20404140
Pubmed	NR1D1 enhances oxidative DNA damage by inhibiting PARP1 activity.	NR1D1 PARP1	1.24e-05	2	123	2	28599788
Pubmed	The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.	ATP1A2 ATP1A4	1.24e-05	2	123	2	10555956
Pubmed	The protein-tyrosine phosphatase DEP-1 promotes migration and phagocytic activity of microglial cells in part through negative regulation of fyn tyrosine kinase.	PTPRJ FYN	1.24e-05	2	123	2	27859601
Pubmed	Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.	HIVEP2 HIVEP3	1.24e-05	2	123	2	2247438
Pubmed	Network organization of the human autophagy system.	CUL3 SRM ATG14 ECPAS MAP3K6 PARP1 RAB3GAP1 RMC1 ULK2	2.68e-05	437	123	9	20562859
Pubmed	Early-onset aging and defective DNA damage response in Cdc14b-deficient mice.	CDC14C CDC14B	3.71e-05	3	123	2	21262768
Pubmed	KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1.	KDM4A KDM4B	3.71e-05	3	123	2	26397136
Pubmed	Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cells.	TXK PARP1	3.71e-05	3	123	2	17177976
Pubmed	Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription.	CDC14C CDC14B	3.71e-05	3	123	2	22355704
Pubmed	Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk.	TXK FYN	3.71e-05	3	123	2	11353545
Pubmed	Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.	KDM4A KDM4B	3.71e-05	3	123	2	17611647
Pubmed	Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.	IPO7 GLI1	3.71e-05	3	123	2	26085085
Pubmed	PARP-1, EpCAM, and FRα as potential targets for intraoperative detection and delineation of endometriosis: a quantitative tissue expression analysis.	PARP1 EPCAM	3.71e-05	3	123	2	39085882
Pubmed	Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.	KDM4A KDM4B	3.71e-05	3	123	2	27266524
Pubmed	CDC14B acts through FZR1 (CDH1) to prevent meiotic maturation of mouse oocytes.	CDC14C CDC14B	3.71e-05	3	123	2	19129509
Pubmed	The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development.	KDM4A KDM4B	3.71e-05	3	123	2	19696013
Pubmed	Cdc14A and Cdc14B Redundantly Regulate DNA Double-Strand Break Repair.	CDC14C CDC14B	3.71e-05	3	123	2	26283732
Pubmed	Dampening of death pathways by schnurri-2 is essential for T-cell development.	HIVEP2 HIVEP3	3.71e-05	3	123	2	21475200
Pubmed	New insights into the GDF9-Hedgehog-GLI signaling pathway in human ovaries: from fetus to postmenopause.	GDF9 GLI1	3.71e-05	3	123	2	33772413
Pubmed	The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.	KDM4A KDM4B	3.71e-05	3	123	2	31434704
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	CUL3 GTPBP4 PHF6 YTHDC2 ZFHX4 BAZ1A ASXL3 AKAP13	4.55e-05	361	123	8	26167880
Pubmed	Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells.	GTPBP4 DGKZ YTHDC2 PARP1 ULK2	5.98e-05	116	123	5	21282530
Pubmed	miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function.	TRPM3 GLP1R	7.41e-05	4	123	2	29101219
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A2 ATP1A4	7.41e-05	4	123	2	21849490
Pubmed	Pelota interacts with HAX1, EIF3G and SRPX and the resulting protein complexes are associated with the actin cytoskeleton.	SRPX EIF3G	7.41e-05	4	123	2	20406461
Pubmed	Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.	KDM4A PINK1	7.41e-05	4	123	2	29413154
Pubmed	Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.	KDM4A KDM4B	7.41e-05	4	123	2	27257215
Pubmed	Mis12 controls cyclin B1 stabilization via Cdc14B-mediated APC/CCdh1 regulation during meiotic G2/M transition in mouse oocytes.	CDC14C CDC14B	7.41e-05	4	123	2	32341029
Pubmed	CDC14A phosphatase is essential for hearing and male fertility in mouse and human.	CDC14C CDC14B	7.41e-05	4	123	2	29293958
Pubmed	The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.	KDM4A KDM4B	7.41e-05	4	123	2	31014673
Pubmed	A mammalian homolog of Drosophila schnurri, KRC, regulates TNF receptor-driven responses and interacts with TRAF2.	HIVEP3 TNFRSF1B	7.41e-05	4	123	2	11804591
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HIVEP2 PDE9A CMC1 PHF6 TECTA ECPAS CDC14B HIVEP3 MALT1 PPP2R3A PTPRJ GUCY1A1 AKAP13 PCCA PRDM15 KDM4B	7.42e-05	1489	123	16	28611215
Pubmed	Multiple genes encode the human Na+,K+-ATPase catalytic subunit.	ATP1A2 ATP1A4	1.23e-04	5	123	2	3035563
Pubmed	Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.	KDM4A KDM4B	1.23e-04	5	123	2	21914792
Pubmed	Decreased levels of metabolic enzymes in pancreatic islets of patients with type 2 diabetes.	OXCT1 PCCA	1.23e-04	5	123	2	19296078
Pubmed	The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation.	TXK FYN	1.23e-04	5	123	2	15175272
Pubmed	Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.	PARP1 GFPT2	1.23e-04	5	123	2	20353610
Pubmed	Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.	KDM4A KDM4B	1.23e-04	5	123	2	16738407
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R45 TAS2R30 TAS2R46	1.33e-04	28	123	3	15744053
Pubmed	The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.	ATP1A2 ATP1A4	1.84e-04	6	123	2	3036582
Pubmed	Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.	KDM4A KDM4B	1.84e-04	6	123	2	15927959
Pubmed	XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7.	CUL3 XAF1	1.84e-04	6	123	2	36394357
Pubmed	Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling.	PTPRJ FYN	1.84e-04	6	123	2	21098033
Pubmed	Identification and characterization of JMJD2 family genes in silico.	KDM4A KDM4B	1.84e-04	6	123	2	15138608
Pubmed	The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.	ATG14 ULK2	1.84e-04	6	123	2	27046250
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	DMTF1 HIVEP2 ZFAND5 NR1D1 BAZ1A GLI1 ZFAND6 KDM4A TOP3A KDM4B	2.21e-04	709	123	10	22988430
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R31 TAS2R30 TAS2R46	2.38e-04	34	123	3	15496549
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	CUL3 HIVEP2 IPO7 SRM YTHDC2 USP46 PARP1 SASS6 KDM4A SRPX EIF3G ZMYM6	2.42e-04	1005	123	12	19615732
Pubmed	Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.	ATP1A2 ATP1A4	2.58e-04	7	123	2	10837135
Pubmed	Molecular genetics of Na,K-ATPase.	ATP1A2 ATP1A4	2.58e-04	7	123	2	2158121
Pubmed	Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.	KDM4A KDM4B	2.58e-04	7	123	2	21445275
Pubmed	Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2.	TXK FYN	2.58e-04	7	123	2	9047237
Pubmed	Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.	PTPRJ PTPRM	2.58e-04	7	123	2	15978577
Pubmed	In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.	CRISPLD2 ZFAND5 MAP3K6 GREM2 OXCT1	2.70e-04	160	123	5	23375831
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	GTPBP4 IPO7 MYSM1 PARP1 SLC4A1AP BAZ1A KDM4A PRDM15 KDM4B	3.24e-04	608	123	9	36089195
Pubmed	Th1 Cells Rolling on Selectins Trigger DAP12-Dependent Signals That Activate Integrin αLβ2.	TXK FYN	3.43e-04	8	123	2	31757864
Pubmed	Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation.	RC3H1 MALT1	3.43e-04	8	123	2	25282160
Pubmed	CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progression.	CUL3 ATG14	3.43e-04	8	123	2	33977871
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	CUL3 PSKH1 MAP3K6 NR1I2 HASPIN FYN PINK1	3.72e-04	372	123	7	22939624
Pubmed	Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection.	ATG14 ULK2	4.39e-04	9	123	2	26649827
Pubmed	Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.	CUL3 GLI1	4.39e-04	9	123	2	20081843
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ASXL3 ITPRIP TMEM108 SSH2	4.84e-04	102	123	4	11214970
Pubmed	Functional genomics identifies therapeutic targets for MYC-driven cancer.	ARFGEF2 TXK GLI1 HASPIN	5.03e-04	103	123	4	22623531
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KDM4A PRDM15 KDM4B	5.14e-04	44	123	3	24183668
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	CUL3 GTPBP4 IPO7 CMC1 PHF6 ECPAS PARP1 GFPT2 EIF3G	5.41e-04	653	123	9	33742100
Pubmed	Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia.	CUL3 PARP1 FYN	5.86e-04	46	123	3	37207277
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PLEKHB2 HIVEP2 PDE9A ARFGEF2 MED13L NR1D1 PARP1 ADAMTS9 RNF216 KDM4A GFPT2 ATP1A2 PINK1	6.43e-04	1285	123	13	35914814
Pubmed	Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.	KDM4A KDM4B	6.68e-04	11	123	2	19144645
Pubmed	The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.	CUL3 GLI1	6.68e-04	11	123	2	27621083
Pubmed	Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia.	GLI1 EPCAM	6.68e-04	11	123	2	33882290
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CUL3 TRPM3 SLC4A1AP ITPRIP AKAP13 GFPT2 SSH2 EIF3G PRDM15	7.92e-04	689	123	9	36543142
Pubmed	Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.	SH3TC2 ATP8B4 ZNF721	7.94e-04	51	123	3	11853319
Pubmed	Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).	NR1D1 NR1I2	8.00e-04	12	123	2	16219912
Pubmed	Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation.	ATP1A2 ATP1A4	9.43e-04	13	123	2	10920231
Pubmed	Identification and characterization of human taste receptor genes belonging to the TAS2R family.	TAS2R31 TAS2R46	9.43e-04	13	123	2	12584440
Pubmed	Proximity labeling reveals dynamic changes in the SQSTM1 protein network.	PHF6 YTHDC2 ZFAND5 ZFAND6 SASS6 PCCA	1.03e-03	322	123	6	39098523
Pubmed	KCTD10 is involved in the cardiovascular system and Notch signaling during early embryonic development.	CUL3 TNFRSF1B	1.10e-03	14	123	2	25401743
Pubmed	Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.	KDM4A KDM4B	1.10e-03	14	123	2	16603238
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CUL3 RC3H1 USP46 TRPM3 GFPT2 SSH2 ATP1A2 FYN ULK2	1.18e-03	730	123	9	34857952
Pubmed	Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells.	GDF9 GLI1	1.26e-03	15	123	2	25917826
Pubmed	A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.	LRRC32 TMEM108	1.44e-03	16	123	2	22036096
Pubmed	Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.	CRISPLD2 GREM2 GLI1 ATP1A2	1.58e-03	140	123	4	26930384
Pubmed	Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.	IPO7 PARP1	1.63e-03	17	123	2	21825151
Cytoband	12p13.2	CLEC1A TAS2R31 TAS2R30 TAS2R46	6.29e-06	45	121	4	12p13.2
GeneFamily	Taste 2 receptors	TAS2R33 TAS2R45 TAS2R31 TAS2R30 TAS2R46	1.10e-06	39	86	5	1162
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A2 ATP1A4	4.62e-04	7	86	2	1208
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	HIVEP2 ZNF652 HIVEP3 BNC1 ZNF716 ZNF117 ZBTB39 GLI1 ZNF721 ZNF749 PRDM15	5.83e-04	718	86	11	28
GeneFamily	Zinc fingers AN1-type\|UPF1 like RNA helicases	ZFAND5 ZFAND6	6.15e-04	8	86	2	63
GeneFamily	Tudor domain containing	TDRD9 KDM4A KDM4B	7.18e-04	37	86	3	780
Coexpression	GSE14350_TREG_VS_TEFF_UP	DGKZ MYSM1 GUCY1A1 ITPRIP SSH2 TNFRSF1B FYN PRDM15	4.15e-06	199	121	8	M3417
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 BNC1 GLI1 SRPX GFPT2 ATP1A2	7.54e-07	185	121	7	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 BNC1 GLI1 SRPX GFPT2 ATP1A2	7.54e-07	185	121	7	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MED13L PTPRJ PTPRM TRPM3 AKAP13 SSH2 PCCA	9.67e-07	192	121	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 NR1D1 GREM2 SRPX GFPT2 ATP1A2	1.00e-06	193	121	7	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A HIVEP3 PTPRM ITPRIP XAF1 FYN	1.19e-06	198	121	7	07701c73137947ed4a27e225975329235bbb8734
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A HIVEP3 PTPRM ITPRIP XAF1 FYN	1.19e-06	198	121	7	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A HIVEP3 PTPRM ITPRIP XAF1 FYN	1.19e-06	198	121	7	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A HIVEP3 PTPRM ITPRIP XAF1 FYN	1.19e-06	198	121	7	440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 TMIGD1 SRPX GFPT2 ATP1A2	9.29e-06	178	121	6	27497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 TMIGD1 SRPX GFPT2 ATP1A2	9.29e-06	178	121	6	d348a9550db940d204706529759dc51e30506b5f
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP2 KCNK9 CDC14B MALT1 ZFHX4 TRPM3	9.59e-06	179	121	6	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	pdx-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP2 KCNK9 CDC14B MALT1 ZFHX4 TRPM3	1.05e-05	182	121	6	7b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	LRRC32 CLEC1A MAP3K6 ITPRIP XAF1 FYN	1.09e-05	183	121	6	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	LPS-IL1RA\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIVEP2 IPO7 CLEC1A ADAMTS9 TNFRSF1B CX3CL1	1.12e-05	184	121	6	c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 BNC1 GLI1 SRPX GFPT2 ATP1A2	1.12e-05	184	121	6	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	LRRC32 CLEC1A PTPRM ADAMTS9 SRPX CX3CL1	1.12e-05	184	121	6	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COPD-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	LRRC32 CLEC1A PTPRM ADAMTS9 SRPX CX3CL1	1.23e-05	187	121	6	be42ee71d3412bb1f52593d8814de85c354a0efa
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.23e-05	187	121	6	35c382c0aabd46906113e5db30ea24bb8e658899
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	LRRC32 CLEC1A PTPRM ADAMTS9 SRPX FYN	1.27e-05	188	121	6	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	Control-Endothelial_cells\|Control / group, cell type (main and fine annotations)	LRRC32 CLEC1A PTPRM ITPRIP XAF1 CX3CL1	1.27e-05	188	121	6	3953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GREM2 GUCY1A1 SRPX ATP1A2	1.31e-05	189	121	6	a5306561026e4dfcc39beeb785e5108ac595d136
ToppCell	facs-Skin-nan-18m-Mesenchymal-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 GREM2 SRPX GFPT2 ATP1A2 TNFRSF1B	1.31e-05	189	121	6	29287525120be2953b76881ba3cfc4379c265e7a
ToppCell	facs-Skin-nan-18m-Mesenchymal-fibroblast\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 GREM2 SRPX GFPT2 ATP1A2 TNFRSF1B	1.31e-05	189	121	6	7150dad9a92a715487c2d8130fa01b752ea69663
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRISPLD2 ZFAND5 STAC2 GUCY1A1 ADAMTS9 ATP1A2	1.31e-05	189	121	6	0daa8efac08dca9525d2b8d421952068cab4eb50
ToppCell	facs-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GREM2 GUCY1A1 SRPX ATP1A2	1.31e-05	189	121	6	381058f55908f84375b54601d617389ef43ab855
ToppCell	facs-Skin-nan-18m-Mesenchymal\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC32 GREM2 SRPX GFPT2 ATP1A2 TNFRSF1B	1.31e-05	189	121	6	6e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCell	5'-Adult-Appendix-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRISPLD2 ZFAND5 STAC2 GUCY1A1 ADAMTS9 ATP1A2	1.31e-05	189	121	6	b6bb4327b4560d07d2b728abcc5f144f428948a5
ToppCell	facs-Kidney-nan-3m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GREM2 GUCY1A1 SRPX ATP1A2	1.31e-05	189	121	6	302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRISPLD2 LRRC32 GUCY1A1 ADAMTS9 GLP1R ATP1A2	1.35e-05	190	121	6	d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 ZFAND5 TMEM196 ZFHX4 SRPX GFPT2	1.39e-05	191	121	6	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC32 CLEC1A PTPRM GUCY1A1 FAM20A CX3CL1	1.39e-05	191	121	6	adb2e3efcad02889d8229325080da5e7830fd3ae
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	CRISPLD2 LRRC32 GUCY1A1 ADAMTS9 GLP1R ATP1A2	1.39e-05	191	121	6	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GUCY1A1 GLI1 SRPX GFPT2	1.43e-05	192	121	6	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	facs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GLI1 SRPX GFPT2 ATP1A2	1.43e-05	192	121	6	a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GUCY1A1 GLI1 SRPX GFPT2	1.43e-05	192	121	6	04d155897ed075c359933080e36a4ab2150b6e9f
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRISPLD2 KDELR3 GLI1 SRPX GFPT2 ATP1A2	1.43e-05	192	121	6	7b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCell	facs-Lung-nan-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GLI1 SRPX GFPT2 ATP1A2	1.43e-05	192	121	6	eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCell	human_hepatoblastoma-Endothelial_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	CLEC1A HIVEP3 ADAMTS9 ITPRIP XAF1 FYN	1.43e-05	192	121	6	e09f609fed033a25baacaf4a07bbbae1076da366
ToppCell	droplet-Kidney-nan-18m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 GUCY1A1 GLI1 SRPX GFPT2	1.43e-05	192	121	6	84149a5c6c3b3c9b86aed77cf8e72d99ef099fab
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A DGKZ PTPRM XAF1 FYN	1.43e-05	192	121	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ARMC9 MED13L PTPRJ PTPRM AKAP13 SSH2	1.47e-05	193	121	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	facs-Heart-RV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 LRRC32 SRPX GFPT2 ATP1A2	1.47e-05	193	121	6	76f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCell	CD8+_Memory_T_cell-CV-0\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	CMC1 DGKZ CDC14B PTPRJ AKAP13 FYN	1.47e-05	193	121	6	995781d87a919c0380750878bafe584342bb83ad
ToppCell	COPD-Endothelial-VE_Arterial\|COPD / Disease state, Lineage and Cell class	LRRC32 CLEC1A PTPRM ADAMTS9 SRPX CX3CL1	1.47e-05	193	121	6	1c701b6ab5f0f0239634adac94fa1c92bf3c36f4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 ZFAND5 TMEM196 ZFHX4 SRPX GFPT2	1.47e-05	193	121	6	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRISPLD2 KDELR3 GLI1 SRPX GFPT2 ATP1A2	1.47e-05	193	121	6	fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCell	Control-Endothelial-VE_Arterial\|World / Disease state, Lineage and Cell class	SH3TC2 LRRC32 CLEC1A ADAMTS9 SRPX CX3CL1	1.47e-05	193	121	6	52c0f2c7af57436f23e0c0e0c87086c47695e2c4
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATP8B4 HIVEP2 MALT1 GUCY1A1 TNFRSF1B FAM20A	1.47e-05	193	121	6	704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A DGKZ PTPRM XAF1 FYN	1.47e-05	193	121	6	52e918884877b6659cdca0496390e440f73694a9
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_5\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATP8B4 HIVEP2 MALT1 GUCY1A1 TNFRSF1B FAM20A	1.51e-05	194	121	6	36f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCell	IPF-Epithelial-Mesothelial\|Epithelial / Disease state, Lineage and Cell class	CRISPLD2 SH3TC2 BNC1 ZFHX4 ADAMTS9 GFPT2	1.51e-05	194	121	6	d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRISPLD2 KDELR3 ZFHX4 ADAMTS9 SRPX GFPT2	1.56e-05	195	121	6	0866aaf053762d1a021fcbccff058526078a99da
ToppCell	facs-Mammary_Gland\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 SRM STAC2 GFPT2 CX3CL1 EPCAM	1.56e-05	195	121	6	21cfcb751e548591fc8724a8329c294da6012e0f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ADAMTS9 ITPRIP XAF1	1.56e-05	195	121	6	818bc18c5834238e5f733cac6fe928ed0788f57d
ToppCell	Control-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	MED13L MALT1 PTPRJ TNFRSF1B FAM20A FYN	1.56e-05	195	121	6	b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCell	ASK452\|World / Donor, Lineage and Cell class of Lung cells from Dropseq	HIVEP2 ADAMTS9 BAZ1A GFPT2 TNFRSF1B CX3CL1	1.56e-05	195	121	6	7efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCell	ASK428-Endothelial-Endothelium\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LRRC32 CLEC1A ADAMTS9 SRPX TAS2R30 CX3CL1	1.61e-05	196	121	6	b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCell	COVID-19-kidney-VWF+PLVAP+VCAM1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.61e-05	196	121	6	ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ADAMTS9 ITPRIP XAF1	1.61e-05	196	121	6	7cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 SRM NR1D1 SRPX ATP1A2	1.61e-05	196	121	6	59b5b5a0c123d0423abd19c312514849004b903b
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CMC1 TXK HIVEP3 ITPRIP AKAP13 TNFRSF1B	1.61e-05	196	121	6	c57a95f8b4d8d6334f269d3c16246684f4222a3e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ADAMTS9 ITPRIP XAF1	1.61e-05	196	121	6	4cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ADAMTS9 ITPRIP XAF1	1.61e-05	196	121	6	d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.61e-05	196	121	6	b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCell	nucseq-Endothelial-Endothelial_Vascular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LRRC32 CLEC1A PTPRM XAF1 SRPX CX3CL1	1.61e-05	196	121	6	686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCell	5'-Adult-Appendix\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRISPLD2 ADAMTS9 ITPRIP SRPX GFPT2 FAM20A	1.61e-05	196	121	6	a579211ef14f348d0c5a290553150222dfbf1515
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.61e-05	196	121	6	d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 KDELR3 SRM NR1D1 SRPX ATP1A2	1.65e-05	197	121	6	b16add329bb35a558287ede51353010dde5bc029
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.65e-05	197	121	6	0f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LRRC32 CLEC1A PTPRM ADAMTS9 FAM20A CX3CL1	1.65e-05	197	121	6	e8e879b7634a29569061d3515d180784094a31e7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.70e-05	198	121	6	451003a21162eeae90739fdb502bb50b362d80c8
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLEC1A HIVEP3 PTPRM ITPRIP XAF1 FYN	1.70e-05	198	121	6	92416e65a0dc1a4bf931833407620ea05d362f56
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRRC32 CLEC1A PTPRM XAF1 FYN CX3CL1	1.70e-05	198	121	6	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LRRC32 CLEC1A PTPRM ITPRIP XAF1 FYN	1.70e-05	198	121	6	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	LRRC32 CLEC1A PTPRM ADAMTS9 FYN CX3CL1	1.75e-05	199	121	6	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	LRRC32 MAP3K6 XAF1 SRPX TNFRSF1B CX3CL1	1.75e-05	199	121	6	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRC32 CLEC1A ITPRIP SRPX FYN CX3CL1	1.75e-05	199	121	6	d58edc5f74970bb26d844746184e4bae7c494d6b
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRISPLD2 KDELR3 SRM GLI1 SRPX GFPT2	1.75e-05	199	121	6	66b4ff23b2e83fb7e6a37fdafdef315cfa33d327
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Mesothelium\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CRISPLD2 BNC1 ZFHX4 ADAMTS9 SRPX GFPT2	1.80e-05	200	121	6	c082bc21ec7c5323439d108ea8aea510e1113c3f
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRC32 CLEC1A TLNRD1 ADAMTS9 ITPRIP CX3CL1	1.80e-05	200	121	6	24fa22fb93c4533a79e5d95d241a60f4b13e5631
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	LRRC32 USP46 MAP3K6 CCDC62 CX3CL1	6.76e-05	156	121	5	ff39712c7a2dc1b85c598d5105789aa291dea726
ToppCell	5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 TXK AKAP13 TAS2R31 FYN	8.31e-05	163	121	5	11cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 TXK RAB3GAP1 HASPIN FYN	9.59e-05	168	121	5	b4b73f3fc9f4c3d87ca0a63ff8b2842141ccd0e6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KDELR3 GTPBP4 ZNF716 OXCT1 TNFRSF1B	9.86e-05	169	121	5	c8691c4f707d46b2865fe46eabe24ea4d03c7b43
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP8B4 CMC1 DGKZ TXK FYN	1.04e-04	171	121	5	f16cb64b8844c2668922c786888efaa9f873afcc
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DGKZ PTPRJ SSH2 TNFRSF1B FAM20A	1.04e-04	171	121	5	355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 PTPRM ITPRIP XAF1 FYN	1.10e-04	173	121	5	f193c63cc536d891c9d23043765e320252bb6e65
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 LRRC32 GUCY1A1 ADAMTS9 ATP1A2	1.10e-04	173	121	5	2415b6ff49f334da570577d4e93484d024a3dbd5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 LRRC32 GUCY1A1 ADAMTS9 ATP1A2	1.10e-04	173	121	5	2acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRISPLD2 LRRC32 ANKRD62 ADAMTS9 GLP1R	1.13e-04	174	121	5	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 TXK HIVEP3 TNFRSF1B FYN	1.19e-04	176	121	5	feafc757e7aa4f17128ff34886beb2fd3461c9ea
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CRISPLD2 NR1D1 GLI1 SRPX GFPT2	1.19e-04	176	121	5	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	COPD-Endothelial-VE_Venous\|World / Disease state, Lineage and Cell class	LRRC32 PTPRM ADAMTS9 SRPX CX3CL1	1.29e-04	179	121	5	9968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 LRRC32 GLI1 SRPX GFPT2	1.29e-04	179	121	5	6f51a4580c06fc55cc764052c9b26f7c55660282
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 LRRC32 GLI1 SRPX GFPT2	1.29e-04	179	121	5	f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	SH3TC2 ZFAND5 TRPM3 ADAMTS9 SRPX	1.29e-04	179	121	5	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 LRRC32 GLI1 SRPX GFPT2	1.29e-04	179	121	5	a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCell	droplet-Lung-nan-18m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD9 PHF6 TECTA DENND4C TXK	1.29e-04	179	121	5	8ebd0c7ac99ac8194fa1a2aac88a893739a97725
ToppCell	IPF-Epithelial-Mesothelial\|IPF / Disease state, Lineage and Cell class	SH3TC2 BNC1 ZFHX4 ADAMTS9 GFPT2	1.32e-04	180	121	5	1fa54bf4dba72866b2295639d991af639341bc08
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LRRC32 PTPRM ADAMTS9 ITPRIP FYN	1.32e-04	180	121	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
Disease	birth weight, parental genotype effect measurement	ARFGEF2 ZFHX4 PTPRJ CRIPT AKAP13 NLRP13	9.96e-05	192	113	6	EFO_0004344, EFO_0005939
Disease	aggressive behavior	ARFGEF2 F11 FYN	1.18e-04	25	113	3	EFO_0003015
Disease	mean arterial pressure	SH3TC2 ZNF652 DGKZ HIVEP3 PTPRJ GUCY1A1 FYN TOP3A KDM4B	1.33e-04	499	113	9	EFO_0006340
Disease	Arterial Fatty Streak	PARP1 NR1I2	1.44e-04	5	113	2	C0015697
Disease	Atheroma	PARP1 NR1I2	1.44e-04	5	113	2	C0264956
Disease	Plaque, Atherosclerotic	PARP1 NR1I2	1.44e-04	5	113	2	C2936350
Disease	Fibroatheroma	PARP1 NR1I2	1.44e-04	5	113	2	C2936351
Disease	factor XI measurement, venous thromboembolism	DGKZ F11 PTPRJ	2.06e-04	30	113	3	EFO_0004286, EFO_0004694
Disease	survival time, coronary artery disease	PDE9A TEKT5 GREM2	2.06e-04	30	113	3	EFO_0000714, EFO_0001645
Disease	Parkinson disease	CCN6 ASXL3 CCDC62 HASPIN GFPT2 FYN PRDM15	2.44e-04	321	113	7	MONDO_0005180
Disease	factor VIII measurement, venous thromboembolism	DGKZ F11 PTPRJ	3.00e-04	34	113	3	EFO_0004286, EFO_0004630
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A2 ATP1A4	3.01e-04	7	113	2	DOID:0060178 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	CUL3 MED13L HIVEP3 ASXL3	4.58e-04	93	113	4	C1535926
Disease	eosinophil percentage of leukocytes	GTPBP4 SH3TC2 HIVEP2 ZNF652 LRRC32 ATG14 HIVEP3 AKAP13 TNFRSF1B CX3CL1	6.01e-04	746	113	10	EFO_0007991
Disease	alopecia areata (is_marker_for)	KDM4A KDM4B	6.41e-04	10	113	2	DOID:986 (is_marker_for)
Disease	polymyositis (is_marker_for)	TNFRSF1B CX3CL1	7.82e-04	11	113	2	DOID:0080745 (is_marker_for)
Disease	nervous system disease (implicated_via_orthology)	ATP1A2 ATP1A4	9.36e-04	12	113	2	DOID:863 (implicated_via_orthology)
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP2 HIVEP3	1.10e-03	13	113	2	DOID:0050787 (implicated_via_orthology)
Disease	Pneumonia	PARP1 TNFRSF1B CX3CL1	1.18e-03	54	113	3	C0032285
Disease	Pneumonitis	PARP1 TNFRSF1B CX3CL1	1.18e-03	54	113	3	C3714636
Disease	Lobar Pneumonia	PARP1 TNFRSF1B CX3CL1	1.18e-03	54	113	3	C0032300
Disease	Experimental Lung Inflammation	PARP1 TNFRSF1B CX3CL1	1.18e-03	54	113	3	C0887898
Disease	Obesity	HTR2C PHF6 PARP1 NR1I2 TNFRSF1B	1.18e-03	205	113	5	C0028754
Disease	Seasonal Affective Disorder	HTR2C NR1D1	1.68e-03	16	113	2	C0085159
Disease	Intellectual Disability	HIVEP2 ARMC9 MED13L PARP1 TRPM3 MAB21L1 ZMYM6	1.70e-03	447	113	7	C3714756
Disease	age at menarche	ECPAS KCNK9 OLFM3 ZFHX4 TRPM3 TMEM108 KDM4A KDM4B	2.07e-03	594	113	8	EFO_0004703
Disease	ascending aortic diameter	MED13L KCNK9 C3orf20 HIVEP3	2.10e-03	140	113	4	EFO_0021787
Disease	borna disease (biomarker_via_orthology)	PARP1 CX3CL1	2.14e-03	18	113	2	DOID:5154 (biomarker_via_orthology)
Disease	venous thromboembolism, fibrinogen measurement	DGKZ F11 PTPRJ	2.19e-03	67	113	3	EFO_0004286, EFO_0004623
Disease	wellbeing measurement, alcohol consumption measurement	GREM2 STAC2 GUCY1A1	2.91e-03	74	113	3	EFO_0007869, EFO_0007878
Disease	Metabolic Syndrome X	HTR2C NR1I2	2.91e-03	21	113	2	C0524620
Disease	portal hypertension (biomarker_via_orthology)	NR1D1 CX3CL1	3.19e-03	22	113	2	DOID:10762 (biomarker_via_orthology)
Disease	spermatogenic failure (is_implicated_in)	CCDC62 C2CD6	3.49e-03	23	113	2	DOID:0111910 (is_implicated_in)
Disease	venous thromboembolism, tissue plasminogen activator measurement	DGKZ F11	3.49e-03	23	113	2	EFO_0004286, EFO_0004791

Protein segments in the cluster

Peptide	Gene	Start	Entry
TVICSKLAAKCLVMK	EPCAM	56	P16422
ICNAMGSKLTCEKIV	CFAP43	1606	Q8NDM7
MNKLKGQKIVSCRIC	EIF3G	146	O75821
CCKNSGVLMVVKCRK	CMC1	41	Q7Z7K0
SKMQRIVRLKSGCTC	CCDC62	541	Q6P9F0
CKMRIEQLKQTICKG	ATG14	116	Q6ZNE5
CCKINKKLKSITMLR	CDC14B	101	O60729
CKQLKRAALGRMCTV	GTPBP4	126	Q9BZE4
LCEKSCNQKLMEKLL	HTR2C	336	P28335
CRESLASCAKVKMKQ	AKAP13	1831	Q12802
LKIKHKCTIEGCNMV	BNC1	381	Q01954
KKGLECLVSILKCMV	ARFGEF2	561	Q9Y6D5
GLMKECTLLKERQCQ	ANKRD62	831	A6NC57
MCKTVICCRVTPLQK	ATP8B4	781	Q8TF62
IIMTKINRCVALKLC	ANO9	391	A1A5B4
CCKINKKLKSITMLR	CDC14C	71	A4D256
KDRCRLMKDTCNTGK	DMTF1	261	Q9Y222
LKCSCRLKAMIVCKG	ASXL3	2211	Q9C0F0
CKICRKKGDAENMVL	BAZ1A	1151	Q9NRL2
TVCKMCLNKLHRKAC	RC3H1	36	Q5TC82
KLQMLNCCIERKKAR	RAB3GAP1	516	Q15042
ICGKTKLGEDMLCLL	ITPRIP	256	Q8IWB1
NRSTCKGCMEKIEKG	PARP1	121	P09874
KRIKKCCGMRNTDVS	KCNK9	141	Q9NPC2
IMLTKCVEQGRTKCE	PTPRJ	1136	Q12913
LQTISKKLKDVCRMC	MED13L	1921	Q71F56
KKLKDVCRMCGISAA	MED13L	1926	Q71F56
CLLKLMGEKGCTVTE	MALT1	91	Q9UDY8
KANLMCKTDIKCRLA	GLP1R	336	P43220
LCLRSTGKNMCAKVA	ARMC9	486	Q7Z3E5
RKKGDDCLMKTTCGT	PSKH1	246	P11801
ISINKAVKCTKMCSL	C2CD6	136	Q53TS8
AVKCTKMCSLLSKND	C2CD6	141	Q53TS8
LALKTLSKVCVKMCD	ECPAS	1226	Q5VYK3
KLGCLLARKGCVEKM	MAP3K6	421	O95382
ANRLTEKCCVETKMK	PINK1	541	Q9BXM7
MILLLGKIWRSKCCK	KDELR3	16	O43731
CSKRKEVLQKTMGFC	IPO7	401	O95373
TLLKMILIKCCDISN	PDE9A	451	O76083
QVVRCDTKMKDRCKG	CRISPLD2	286	Q9H0B8
KQAVLCSCRKDMVKI	KDM4A	301	O75164
GKVATQCTCRKDMVK	KDM4B	301	O94953
RKRMKKVSGACIQCS	KDM4B	856	O94953
TCQLKSELDMLVGKC	GLI1	176	P08151
ACRLRKCLESGMKKE	NR1I2	96	O75469
CRVIRTCKKMGIKTV	PCCA	76	P05165
LKKIQKVKQCRCMSV	GREM2	146	Q9H772
GTDIKMCLDILLKCS	PPP2R3A	226	Q06190
CKMVDKKVSCQVLGL	LRRC32	26	Q14392
CSTKLLILEKMLKSC	GLYATL3	6	Q5SZD4
NITKLNGMVLLCKVC	NR1D1	121	P20393
KCMDQIKKIETTGCN	QTRT2	311	Q9H974
DKRCCIPNKSKMITI	CCN6	301	O95389
CLTLTAKRMARKNCL	ATP1A2	341	P50993
RMKFKSCNTEPCLKQ	ADAMTS9	631	Q9P2N4
CTLENVKNICKTRMK	GFPT2	226	O94808
GICAMCGKKVLDTKN	CRIPT	81	Q9P021
MGCVQCKDKEATKLT	FYN	1	P06241
EKNMISKLKTECGCQ	CUL3	451	Q13618
RKLMLKEDTRAGCKC	C3orf20	671	Q8ND61
KMVSKSINTNKCICL	DENND4C	301	Q5VZ89
LRLCKMDNECTTKIK	F11	371	P03951
ADGKNMRESCCKRKL	HASPIN	261	Q8TF76
AVKCVCNLMIKEPKS	GDF9	171	O60383
MLKSVSRRKCAACKI	DGKZ	121	Q13574
CLKCSKEEKLSLMQS	SASS6	156	Q6UVJ0
LETRLRDCMKKLTCG	OLFM3	206	Q96PB7
MVTNLVEVGRVKCCK	PTPRM	996	P28827
LLLICSLCKHLKKMQ	TAS2R30	196	P59541
LLLICSLCKHLKKMQ	TAS2R31	196	P59538
LLLICSLCKHLKKMQ	TAS2R33	196	P0DSN6
LLLVCSLCKHLKKMQ	TAS2R45	196	P59539
LLLICSLCKHLKKMQ	TAS2R46	196	P59540
KSKDCMLQIVCRDGK	PLEKHB2	71	Q96CS7
FKICKMRPSAKSLVC	TDRD9	1011	Q8NDG6
LQMGGCRKKCLSILK	MAB21L1	241	Q13394
CEQCGKSFARKDMLK	PRDM15	1086	P57071
LSPLSQCCMIKKKTL	FAM20A	446	Q96MK3
QCCMIKKKTLLHLQL	FAM20A	451	Q96MK3
IKANTLCIDKEKCMG	TEKT5	456	Q96M29
ECLTLCKNELISVKM	SH3TC2	196	Q8TF17
KMTAARIRKCHKCGT	RNF216	666	Q9NWF9
KIMEKCTLPLTGKQC	OXCT1	451	P55809
DKVICKQKRCPTLAM	SRPX	111	P78539
CLTLTAKRMARKNCL	ATP1A4	351	Q13733
GMKCTRCTGDNEKVK	CLDN8	101	P56748
NGMIFSKDCKELKRC	CLEC1A	241	Q8NC01
SKLCKDCGIMDGKTV	TPPP2	31	P59282
CKAAQMEVSISKCKL	TECTA	1806	O75443
QKEIKRGTKLMCSLC	PHF6	71	Q8IWS0
EIKRGKRMKCTLCSQ	PHF6	271	Q8IWS0
TCRCKLLCQKLMEKT	SUN5	91	Q8TC36
DGKRKPVLMCFLCKL	ZFHX4	271	Q86UP3
ICGILCAKKKSGLVM	TMEM196	61	Q5HYL7
LKAQPCKMCSSILKD	ZNF749	81	O43361
CFGLIARRKKIMKLC	TMIGD1	236	Q6UXZ0
KNRCFMCRKKVGLTG	ZFAND5	151	O76080
ANQKGLCTKERMICL	SSH2	516	Q76I76
LQRKECKMVILSVCS	RMC1	381	Q96DM3
MSQCCRKIKDTVQKL	RMND5B	61	Q96G75
EAMAKALVACKLCKA	TRPM3	686	Q9HCF6
IVGNSKQGLRCKMCK	STAC2	131	Q6ZMT1
KQGLRCKMCKVSVHL	STAC2	136	Q6ZMT1
KNRCFMCRKKVGLTG	ZFAND6	146	Q6FIF0
QLRKGCKSMNVCKVQ	ZNF721	36	Q8TF20
CKFCKLDMQLSKLEL	XAF1	86	Q6GPH4
CEECGIRCKKPSMLK	HIVEP3	1756	Q5T1R4
KCKNDGKSFCMLSRL	ZNF716	186	A6NP11
KRLVSVCDHCKGKMQ	TLNRD1	31	Q9H1K6
QLMKTALKEDGVLCC	SRM	191	P19623
RKCPQCNKDMVLKTK	TOP3A	656	Q13472
LLKELNKCRLSETMC	ZBTB39	16	O15060
CITMCKKLTEKLNRF	ULK2	931	Q8IYT8
KLRKEMLLSVCQDIC	TXK	361	P42681
LGKMVLCAVVLKCLD	YTHDC2	841	Q9H6S0
MAVLAQCSKCKKTTR	TRIM51G	46	A0A3B3IT33
TCCSKQEAQKRMRVK	USP46	231	P62068
MAKCDGCKRQGKLSE	ZMYM6	556	O95789
NLQLRKGCKSVVECK	ZNF117	46	Q03924
LGGLLKMCLKNCEVI	SLC9C2	41	Q5TAH2
KMCLKNCEVIVLTIL	SLC9C2	46	Q5TAH2
CVIMTQVKKKPLCLQ	TNFRSF1B	281	P20333
VTHRRMQICDKCGKK	ZNF652	266	Q9Y2D9
CEECGIRCKKPSMLK	HIVEP2	1801	P31629
KCNITCSKMTSKIPV	CX3CL1	31	P78423
LLTVCCMKRKKKTAN	TMEM108	486	Q6UXF1
MFCTKLKDLKITGEC	GUCY1A1	1	Q02108
KMLCKALKKSTCRLQ	NLRP13	1026	Q86W25
GKKKEAMIQCSLEAC	SLC4A1AP	421	Q9BWU0
LTCLQKLLECMRKTL	MYSM1	771	Q5VVJ2