Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoimpaired neutrophil phagocytosis

CLCN3 PLAU NCKAP1L

1.26e-0514473MP:0002467
DomainFN3_dom

POMGNT2 PTPRG OBSCN ROBO2 USH2A IL2RB IFNAR2

3.27e-06209577IPR003961
DomainFN3

POMGNT2 PTPRG OBSCN ROBO2 USH2A IL2RB

3.13e-05199576PS50853
DomainFN3

PTPRG OBSCN ROBO2 USH2A IL2RB

2.49e-04185575SM00060
DomainDynein_heavy_chain_D4_dom

DNAH12 DYNC1H1

8.13e-0414572IPR024317
DomainDynein_heavy_dom-2

DNAH12 DYNC1H1

8.13e-0414572IPR013602
DomainDHC_N2

DNAH12 DYNC1H1

8.13e-0414572PF08393
DomainAAA_8

DNAH12 DYNC1H1

8.13e-0414572PF12780
DomainATPase_dyneun-rel_AAA

DNAH12 DYNC1H1

8.13e-0414572IPR011704
DomainAAA_5

DNAH12 DYNC1H1

8.13e-0414572PF07728
DomainDHC_fam

DNAH12 DYNC1H1

9.37e-0415572IPR026983
DomainDynein_heavy_dom

DNAH12 DYNC1H1

9.37e-0415572IPR004273
DomainDynein_heavy

DNAH12 DYNC1H1

9.37e-0415572PF03028
Domainfn3

PTPRG OBSCN ROBO2 USH2A

1.51e-03162574PF00041
DomainRicin_B_lectin

CRYBG1 GALNT5

2.62e-0325572PF00652
DomainRICIN

CRYBG1 GALNT5

3.29e-0328572SM00458
DomainRICIN_B_LECTIN

CRYBG1 GALNT5

3.29e-0328572PS50231
Pubmed

A homozygous deletion within the carbonic anhydrase-like domain of the Ptprg gene in murine L-cells.

PTPRG PLAU

2.64e-0625728453613
Pubmed

Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases.

PTPRG PLAU

2.64e-0625728382771
Pubmed

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

DNAH12 DYNC1H1

7.91e-0635728666668
Pubmed

The murine Fhit locus: isolation, characterization, and expression in normal and tumor cells.

PTPRG PLAU

7.91e-0635729699672
Pubmed

Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors.

CUL1 FBXO42

7.91e-06357234644148
Pubmed

IL-2 receptor signaling is essential for the development of Klrg1+ terminally differentiated T regulatory cells.

IL2RB KLRG1

1.58e-05457222786769
Pubmed

JFK, a Kelch domain-containing F-box protein, links the SCF complex to p53 regulation.

CUL1 FBXO42

2.63e-05557219509332
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ANPEP PLEKHO2 OBSCN TEP1 IL2RB

2.72e-0521457522199357
Pubmed

Two distinct domains within the N-terminal region of Janus kinase 1 interact with cytokine receptors.

IL2RB IFNAR2

3.94e-05657212133952
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH12 PLAU DYNC1H1

6.43e-05475738812413
Pubmed

A genome-wide CRISPR screen identifies FBXO42 involvement in resistance toward MEK inhibition in NRAS-mutant melanoma.

CUL1 FBXO42

7.34e-05857231549767
Pubmed

Ataxin-3 promotes genome integrity by stabilizing Chk1.

CUL1 DYNC1H1

9.43e-05957228180282
Pubmed

Typing recombinant inbred mouse strains for microsatellite markers.

ANPEP PLAU

9.43e-0595728507976
Pubmed

Defining the membrane proteome of NK cells.

XRN2 CLCN3 TMEM237 CERS6 IL2RB PIGO DYNC1H1 DHRS7B NCKAP1L

1.11e-04116857919946888
Pubmed

The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex.

IL2RB IFNAR2

1.18e-041057212960323
Pubmed

AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.

AGAP11 CHRM5

1.18e-041057220664521
Pubmed

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.

CUL1 USH2A

1.44e-041157224349473
Pubmed

Cand1-Mediated Adaptive Exchange Mechanism Enables Variation in F-Box Protein Expression.

CUL1 FBXL16

2.03e-041357229499133
Pubmed

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.

CUL1 PLA2G15

2.37e-041457210230407
Pubmed

Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population.

IL2RB IFNAR2

2.37e-041457218715339
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH12 DYNC1H1

2.37e-04145729373155
Pubmed

Genome-wide association study of recurrent early-onset major depressive disorder.

PTPRG CYB561D1

3.12e-041657220125088
Pubmed

Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.

USH2A ADCY2

3.12e-041657217567809
Pubmed

Slit2 activity in the migration of guidepost neurons shapes thalamic projections during development and evolution.

ROBO2 LHX6

3.53e-041757221435555
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

PTPRG TMEM237 CASKIN2 PLEKHO2 ANKRD50

3.84e-0437757538117590
Pubmed

IL-2 and IL-15 regulate CD8+ memory T-cell differentiation but are dispensable for protective recall responses.

IL2RB KLRG1

3.97e-041857226426795
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

CUL1 FBXO42

4.43e-041957221572392
Pubmed

F-box protein FBXL16 binds PP2A-B55α and regulates differentiation of embryonic stem cells along the FLK1+ lineage.

CUL1 FBXL16

6.53e-042357224390425
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ARFGEF3 PTPRG FBXO42 OBSCN SRPK2 CERS6 TEP1 DHRS7B XPO7

6.64e-04148957928611215
Pubmed

Dimerization quality control ensures neuronal development and survival.

CUL1 KBTBD6

7.12e-042457230190310
Pubmed

Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development.

ALOXE3 CERS6

9.02e-042757223096701
Pubmed

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.

CUL1 KBTBD6 MTFMT

1.02e-0312057327565346
Pubmed

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability.

CUL1 FBXO42

1.27e-033257235813202
Pubmed

Genetic variations in humans associated with differences in the course of hepatitis C.

IL2RB IFNAR2

1.27e-033257215063762
Pubmed

Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients.

IL2RB IFNAR2

1.35e-033357219817957
Pubmed

Role of inflammation gene polymorphisms on pain severity in lung cancer patients.

IL2RB IFNAR2

1.35e-033357219773451
Pubmed

The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon.

ROBO2 LHX6

1.43e-033457225631876
Pubmed

Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.

IL2RB IFNAR2

1.60e-033657220811626
Pubmed

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

CUL1 FBXL16

1.60e-033657224035498
GeneFamilyFibronectin type III domain containing

PTPRG OBSCN ROBO2 USH2A

8.49e-04160484555
ToppCellAdult-Epithelial-basal_cell-D122|Adult / Lineage, Cell type, age group and donor

KBTBD6 TMEM237 RHBDL1 LHX6 ADCY2

1.46e-0615456538d346402417960044ae999e61f0092b46f2b591
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KNTC1 TAS2R4 CYB561D1 ROBO2 ADCY2

1.99e-06164565583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

ARFGEF3 ABCA13 CYP24A1 TMC5 ADCY2

4.09e-0619056551ca9ef4df3220487152fcf684147730637c7cc1
ToppCellDiffer-Basal|World / shred by cell class for mouse tongue

TSPAN12 ANPEP ROBO2 PLAU LHX6

4.52e-06194565851eff82c9f3d44c86e3e127a804bbd1fced6a7c
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

ARFGEF3 DNAH12 PTPRG ABCA13 TMC5

4.75e-06196565af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

ARFGEF3 DNAH12 PTPRG ABCA13 TMC5

4.75e-061965656d02d494196e3f857d53eea46d9419690d43beca
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 GALNT5 TMC5

5.25e-062005650cc7ff7b6a4eb05d2370ec2f3b9dbfe8cb0699de
ToppCellBronchus_Control_(B.)-Epithelial-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ARFGEF3 DNAH12 ABCA13 GALNT5 TMC5

5.25e-06200565f5bc7d30aa03dd0f95eb64255bd1a2543be8d327
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 GALNT5 TMC5

5.25e-06200565b9cede2e0939c6b60ce1aa16d7efaaae79354580
ToppCellBAL-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 GALNT5 TMC5

5.25e-06200565b762bf6f432eac05a476f6e2ab4da27dd13a2317
ToppCellBAL-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 GALNT5 TMC5

5.25e-062005654c63204e0d868dd4c11c1604a238624a3ad54485
ToppCellSevere_COVID-19-Epithelial|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ARFGEF3 DNAH12 ABCA13 GALNT5 TMC5

5.25e-0620056549910efb6d888c208cd50530b03af19f87070630
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CASKIN2 ANKRD50 TEP1 KLRG1

2.60e-05136564edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CASKIN2 ANKRD50 TEP1 KLRG1

2.60e-0513656403e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Tshz2-Syt2_(Layer_5a,_Entorhinal_cortex,_Tshz1+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNAH12 ABCA13 IL2RB

3.65e-0551563adc73d6909d75ad432aef884dae540b7e48cecd6
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLAU CERS6 TEP1 XPO7

4.44e-051565648349604bd801e20d33770f7d8243598c3756302b
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CLCN3 CYB561D1 ROBO2 GALNT5

4.90e-05160564636127753e3a22831f39d4c8170df40901e4329d
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CLCN3 CYB561D1 ROBO2 GALNT5

4.90e-05160564cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO2 PLAU MARCHF11 LHX6

5.52e-051655646d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO2 PLAU MARCHF11 LHX6

5.52e-0516556484f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP24A1 CAPN6 OBSCN PLA2G15

5.79e-05167564a4a795751644b22af616335379e64ae95175180c
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARFGEF3 FBXL16 RHBDL1 ADCY2

6.20e-0517056498d13dbd76a826e47d55553f9d11f71c043b573e
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

CYP24A1 GALNT5 ANKRD50 IFNAR2

6.34e-05171564adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 GALNT5 TMC5 CHRM5

6.63e-05173564176b956e71d98e8275d698b39437fc326e5fe449
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 POMGNT2 CAPN6 KLRG1

6.63e-051735649f892d756d05e573af018db64edb130ff187ad47
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CAPN6 TEP1 ADCY2 DHRS7B

7.41e-05178564a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH12 ABCA13 CYP24A1 TMC5

7.74e-051805641f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 ABCA13 OBSCN USH2A

8.42e-051845642cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 ABCA13 OBSCN USH2A

8.42e-05184564ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC2_(21)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CRYBG1 IL2RB KLRG1 NCKAP1L

8.42e-0518456433db879e629821fb75684e60f8f0749cf9623bdd
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 ABCA13 OBSCN USH2A

8.42e-051845642b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSPAN12 ANKRD50 TMC5 MARCHF11

8.60e-051855644c42bd3cd72f91f4d4ebb849069a03761a2cd662
ToppCellCOPD-Epithelial-Goblet|World / Disease state, Lineage and Cell class

ARFGEF3 ABCA13 CYP24A1 TMC5

8.78e-05186564d75fe7640a4b2c450c9759a1b3c3ef2a087f0092
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ARFGEF3 PTPRG ABCA13 TMC5

8.78e-05186564acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ARFGEF3 PTPRG ABCA13 TMC5

9.15e-05188564ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

ARFGEF3 DNAH12 TMC5 IL2RB

9.15e-05188564186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellMacrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ANPEP PLEKHO2 PLA2G15 NCKAP1L

9.34e-05189564c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH12 ABCA13 CYP24A1 TMC5

9.34e-05189564b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-051915647b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-051915649f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellHealthy_Control-Epithelial-Epithelial-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-0519156428caedb2e448e0c7f494100d714fa7cdcf150691
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-051915645129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellHealthy_Control-Epithelial-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-0519156415b9386b26caaa7d15f704c4a18881e1ce918a21
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class （2021.01.30）

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564b78547dae8328244a47c83346447bdd787efbcae
ToppCellHealthy_Control-Epithelial|Healthy_Control / Condition, Lineage, Cell class and cell subclass

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564fdcdadbfc9ccae175abe4de8c7428ac4f6a67fde
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class （2021.01.30）

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-05191564cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

ARFGEF3 DNAH12 ABCA13 TMC5

9.73e-051915646228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

ARFGEF3 ABCA13 CYP24A1 TMC5

9.92e-0519256493b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-Dividing_AT2|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CAPN6 ALOXE3 GALNT5 TMC5

1.01e-0419356444839a606ae2f8e37421bda46d588189e1c943d2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANPEP PLEKHO2 ALOXE3 AGAP11

1.05e-04195564d53585715c7f5827c4f5a6db11cb31857ee9d4f0
ToppCellGoblet_1|World / shred by cell class for nasal brushing

ARFGEF3 ANPEP GALNT5 TMC5

1.05e-04195564d9e4889a2e7b7c97c07c15b043b77837739462e4
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 ABCA13 TMC5 ADCY2

1.05e-04195564e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Ptgfr_(Postsubiculum)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

CYP24A1 TMC5 IL2RB

1.07e-047356327644d9b67ef933af0c77936cabdbd81f05c8562
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Ptgfr_(Postsubiculum)|Hippocampus / BrainAtlas - Mouse McCarroll V32

CYP24A1 TMC5 IL2RB

1.07e-0473563e97b773931a64f7356f44c6950186f7bbbeb3e8d
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ARFGEF3 ANPEP TMC5 ADCY2

1.07e-04196564057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCell367C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM237 RHBDL1 PLAU LHX6

1.07e-04196564e8db58e82300981f981402618a1befb91f6690fd
ToppCell367C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM237 RHBDL1 PLAU LHX6

1.07e-041965642cf42b702ea15adfa6bbd86a3c9613271863f86c
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ARFGEF3 DNAH12 ABCA13 TMC5

1.10e-04197564272c7f4e582ef57564450540242b0db766b78328
ToppCellCOVID-19-Epithelial|COVID-19 / Condition, Lineage and Cell class

ARFGEF3 DNAH12 ABCA13 TMC5

1.10e-0419756418fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCellBL-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 DNAH12 ABCA13 TMC5

1.12e-041985646218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

TSPAN12 ARFGEF3 ROBO2 TMC5

1.12e-04198564a3d4b6e4259ded2193d94d2ff6d48cf67214fc35
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ARFGEF3 ANPEP TMC5 ADCY2

1.12e-041985646712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellNS-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 ABCA13 GALNT5 TMC5

1.12e-041985644a481e1edb80b950c823ed926842cd5132cfb27f
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 DNAH12 ANPEP ABCA13

1.12e-041985641fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-041995641ee4010d8557564e25e8ee00b914c2dfd9037838
ToppCellBAL-Mild-Epithelial-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-041995641df69c0cb5f759f6a2152521842506a75bb95cae
ToppCellMild-Epithelial-Epithelial-|Mild / Condition, Lineage, Cell class and cell subclass

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-0419956481115bbd2c10bfdd38376d2075f03a59c31870d2
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-0419956474087b4b5e567310fc4ac58fb267ff651a180680
ToppCellBAL-Mild-Epithelial|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-0419956400b5ce099c50a5e1786ce2b3a06ee0931a8205a4
ToppCellMild-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-04199564ec5fff80e2a8a94fbaf1fdcc6d45c8d7c6252e18
ToppCellMild-Epithelial-Epithelial|Mild / Condition, Lineage, Cell class and cell subclass

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-0419956491308b255783ad4029e5575028c18d7550832c51
ToppCellNS-moderate-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 ABCA13 GALNT5 TMC5

1.14e-04199564aa2b51940115c22768c0d7493b4b60d41df3f376
ToppCellMild_COVID-19-Epithelial|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

ARFGEF3 DNAH12 ABCA13 TMC5

1.14e-0419956472689bda7476930887ae007682fcab27f956f050
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ARFGEF3 DNAH12 ABCA13 TMC5

1.16e-04200564d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellmoderate-Epithelial|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ARFGEF3 ABCA13 GALNT5 TMC5

1.16e-04200564095783c9b75113ae350c2d5fb1195d71b41fa695
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 DNAH12 ABCA13 TMC5

1.16e-0420056421d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ARFGEF3 ABCA13 GALNT5 TMC5

1.16e-04200564d014959891893b6d3854a471fba1dc50c6625a0a
ToppCellSevere-Epithelial-Epithelial-|Severe / Condition, Lineage, Cell class and cell subclass

ARFGEF3 ABCA13 GALNT5 TMC5

1.16e-042005648669ce08f93eefb8ac970e30cdc4b1f908023c54
ToppCellControl_saline-Endothelial-Endothelial-Alv_Gen_Intermediate|Control_saline / Treatment groups by lineage, cell group, cell type

TSPAN12 PTPRG CASKIN2 IFNAR2

1.16e-04200564041a34080120c9f613373c20dcc366292f558040
ToppCellSevere-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

ARFGEF3 ABCA13 GALNT5 TMC5

1.16e-042005646ead9db88568bb829d564a6d8e85f71fd765bac0
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TSPAN12 CASKIN2 ANKRD50 DYNC1H1

1.16e-0420056479e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLung_Parenchyma-Severe-Epithelial|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 DNAH12 ABCA13 TMC5

1.16e-0420056433658d5d09e2eaff60f4dd88837d4252328eab63
ToppCellParenchyma_COVID-19-Epithelial-TX-Club|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ARFGEF3 ABCA13 CYP24A1 TMC5

1.16e-0420056485f946dd3831acf3488c87efba96689cc2667c3a
ToppCellParenchyma_COVID-19-Epithelial-TX|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ARFGEF3 DNAH12 ABCA13 TMC5

1.16e-04200564d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CYP24A1 OBSCN GALNT5 IL2RB

1.16e-042005649da214f756a03516eaafde00289b90f69623b9f3
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARFGEF3 ABCA13 CYP24A1 TMC5

1.16e-042005648a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARFGEF3 ABCA13 CYP24A1 TMC5

1.16e-0420056430d428510c68da96c7c8cfd472f449ebb9631132
ToppCellSevere-Epithelial-Epithelial|Severe / Condition, Lineage, Cell class and cell subclass

ARFGEF3 ABCA13 GALNT5 TMC5

1.16e-042005643bd1ce2793651c9badd69f011d2531183594e5f4
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

ROBO2 VARS2

6.61e-057532DOID:0060475 (implicated_via_orthology)
Diseasesusceptibility to mononucleosis measurement

CUL1 ANKRD50 ADCY2

2.64e-0469533EFO_0008403
Diseasehepatitis B (is_marker_for)

PLAU IL2RB

6.50e-0421532DOID:2043 (is_marker_for)
Diseaseattention deficit hyperactivity disorder, bipolar disorder

PTPRG ADCY2

1.42e-0331532EFO_0003888, MONDO_0004985
Diseasesphingomyelin measurement

CERS6 USH2A KLRG1 DYNC1H1

1.57e-03278534EFO_0010118
Diseasevisceral adipose tissue measurement

KNTC1 PTPRG CRYBG1 ROBO2 ADCY2

1.70e-03481535EFO_0004765

Protein segments in the cluster

PeptideGeneStartEntry
IAVLVYWRGCNKIKS

PTPRG

756

P23470
QAQIKGAAWYLCLAL

CYB561D1

191

Q8N8Q1
CRKGNVVLAQLLIWY

AGAP11

496

Q8TF27
NVCLLEAYNWVKARR

DUSP14

131

O95147
LKGCIVWLDVINHLY

ABCA13

1391

Q86UQ4
ALACSKELWILNRYL

ANPEP

831

P15144
NGLYLWLCQRLFVRK

ANKRD50

331

Q9ULJ7
IIDCWIDNIRLVYNK

PLA2G15

86

Q8NCC3
AALVCKQWYRLIKGV

FBXO42

71

Q6P3S6
GRQQYVAAPLCLLWL

ALOXE3

341

Q9BYJ1
LKVQAQWLYLEPIFC

DNAH12

906

Q6ZR08
WKLCLQGSLYITLIR

NCKAP1L

281

P55160
LKEGNLVCAQYLWLR

KNTC1

556

P50748
YLLKVNNLIWHVRCL

LHX6

81

Q9UPM6
YLVWVRCIFNKILLG

POMGNT2

556

Q8NAT1
LRLYTCQEWAVVKVQ

IQCF6

36

A8MYZ5
WLCALGLPQYHKQLV

CASKIN2

566

Q8WXE0
AGLRRKVLWCLQYIG

GPR75

381

O95800
IVTLKWIGYICLRNS

IFNAR2

261

P48551
VAAPVKWCYGNNVLR

OBSCN

3211

Q5VST9
VLCGVIGLQKWQYDV

ADCY2

391

Q08462
LSVLLYQWILCQGSN

KLRG1

51

Q96E93
QLHLALCWIVRKYDI

CYP24A1

471

Q07973
KVLNGICAYLNRHWV

CUL1

131

Q13616
LQQFNYTWLRLIKCG

GALNT5

841

Q7Z7M9
ARYILVGCWKNLIDT

ARFGEF3

861

Q5TH69
VYLLINCRNTGPWLK

IL2RB

261

P14784
QSQILLVYCKDGWIG

MTFMT

316

Q96DP5
VQGLNCFWSYLIVKI

CERS6

311

Q6ZMG9
AVWQRKDILFQICYG

MARCHF11

271

A6NNE9
DLVNYQNKCRLIRGW

DYNC1H1

1476

Q14204
LQWVRGKAYLRNAVV

DHRS7B

41

Q6IAN0
LIKVVRGCWILYEQP

CRYBG1

1056

Q9Y4K1
QIWIYQEGCIKCRIA

CRYBG1

1626

Q9Y4K1
CWNLARGYPKVVTQI

CAPN6

506

Q9Y6Q1
CYNVKRNQWALVAPL

KBTBD6

456

Q86V97
VLAQVCKAWRRVLYQ

FBXL16

116

Q8N461
VIEYLLKNQWFVRCQ

VARS2

471

Q5ST30
QVDLLLGLSYCNGKW

USH2A

1786

O75445
PWCYVQVGLKLLVQE

PLAU

131

P00749
LNLPNCWLYQSVKLL

SLC36A2

331

Q495M3
CWLYQSVKLLYIAGI

SLC36A2

336

Q495M3
FLCYGARLNKWVLQT

RHBDL1

211

O75783
ILCWQYLVGKRTVPL

CHRM5

166

P08912
VYSAIWQLCLALIFK

CLCN3

496

P51790
LAGCAVWNIVVIYVL

TMEM237

236

Q96Q45
YWQRVNSKCLFVGIL

TEP1

801

Q99973
WIIKSNYQGLPVRCV

SRPK2

176

P78362
RKVVQSYVEGLCWVL

XRN2

536

Q9H0D6
IIQEYKIWCLGNETR

ROBO2

771

Q9HCK4
GYCGTVKRNLLLLAW

TSPAN12

81

O95859
QALIQLYARITKLGW

XPO7

106

Q9UIA9
KNLWYGACVAALVAL

PIGO

666

Q8TEQ8
WKDRYLLLCQAQLLV

PLEKHO2

36

Q8TD55
LKISIIGILCYYWLN

TMC5

701

Q6UXY8
KYIRSFILVLCWILN

VN1R3

126

Q9BXE9
NQGVILSCKRLYRWK

TIGD7

331

Q6NT04
VWFVTLLNILYCVKI

TAS2R4

96

Q9NYW5
QRLQKLWVGRLILYS

LNPK

36

Q9C0E8