Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DYNC2H1 DNAH7 DNAH6

1.86e-06181024GO:0008569
GeneOntologyMolecularFunctionhistone H4K16 acetyltransferase activity

KAT6A KAT8 MSL3

1.06e-0591023GO:0046972
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNHD1 DYNC2H1 DNAH7 DNAH6

1.20e-05281024GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNHD1 DYNC2H1 DNAH7 DNAH6

3.72e-05371024GO:0045505
GeneOntologyMolecularFunctionN-acyltransferase activity

TLCD3B NAA15 KAT6A KAT8 MSL3

1.77e-041021025GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

NAA15 MOGAT2 KAT6A KAT8 MSL3

1.94e-041041025GO:0016407
GeneOntologyMolecularFunctionhistone H4 acetyltransferase activity

KAT6A KAT8 MSL3

2.13e-04231023GO:0010485
GeneOntologyMolecularFunctionmicrotubule motor activity

DNHD1 DYNC2H1 DNAH7 DNAH6

4.54e-04701024GO:0003777
GeneOntologyMolecularFunctionN-acetyltransferase activity

NAA15 KAT6A KAT8 MSL3

6.85e-04781024GO:0008080
GeneOntologyMolecularFunctionhistone H4K8 acetyltransferase activity

KAT6A KAT8

1.38e-03111022GO:0043996
GeneOntologyMolecularFunctionhistone H4K5 acetyltransferase activity

KAT6A KAT8

1.38e-03111022GO:0043995
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

TLCD3B NAA15 MOGAT2 KAT6A KAT8 MSL3

1.40e-032381026GO:0016747
GeneOntologyCellularComponentinner dynein arm

DNHD1 DNAH7 DNAH6

1.32e-05101023GO:0036156
GeneOntologyCellularComponentdynein complex

DNHD1 DYNC2H1 DNAH7 DNAH6

1.40e-04541024GO:0030286
GeneOntologyCellularComponent9+2 motile cilium

DNHD1 IFT27 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

1.67e-042381027GO:0097729
GeneOntologyCellularComponentMSL complex

KAT8 MSL3

2.34e-0451022GO:0072487
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DNAH7 DNAH6

2.40e-04251023GO:0005858
GeneOntologyCellularComponentmotile cilium

CFAP47 DNHD1 IFT27 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

3.50e-043551028GO:0031514
DomainDynein_HC_stalk

DNHD1 DYNC2H1 DNAH7 DNAH6

7.73e-07141014IPR024743
DomainDynein_heavy_dom-2

DNHD1 DYNC2H1 DNAH7 DNAH6

7.73e-07141014IPR013602
DomainDHC_N2

DNHD1 DYNC2H1 DNAH7 DNAH6

7.73e-07141014PF08393
DomainMT

DNHD1 DYNC2H1 DNAH7 DNAH6

7.73e-07141014PF12777
DomainDHC_fam

DNHD1 DYNC2H1 DNAH7 DNAH6

1.05e-06151014IPR026983
DomainDynein_heavy_dom

DNHD1 DYNC2H1 DNAH7 DNAH6

1.05e-06151014IPR004273
DomainDynein_heavy

DNHD1 DYNC2H1 DNAH7 DNAH6

1.05e-06151014PF03028
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH7 DNAH6

5.35e-05141013IPR024317
DomainAAA_8

DYNC2H1 DNAH7 DNAH6

5.35e-05141013PF12780
DomainARM-type_fold

USP34 DOCK9 AP3B1 LYST PPP4R4 PPP4R3A XPO5 PIK3C2G CTNND2

9.27e-053391019IPR016024
DomainPH_dom-like

DOCK9 ARHGEF12 LYST FRMD4B TIAM2 PPP4R3A ARHGEF40 RANBP3L CADPS ARHGEF4

1.04e-0442610110IPR011993
Domain-

DOCK9 ARHGEF12 FRMD4B TIAM2 PPP4R3A ARHGEF40 RANBP3L CADPS ARHGEF4

2.70e-0439110192.30.29.30
DomainMOZ_SAS

KAT6A KAT8

2.86e-0451012PF01853
DomainHAT_MYST-type

KAT6A KAT8

2.86e-0451012IPR002717
DomainMYST_HAT

KAT6A KAT8

2.86e-0451012PS51726
DomainDH_1

ARHGEF12 TIAM2 ARHGEF40 ARHGEF4

3.76e-04631014PS00741
DomainTudor-knot

KAT8 MSL3

4.28e-0461012IPR025995
DomainTudor-knot

KAT8 MSL3

4.28e-0461012PF11717
DomainRhoGEF

ARHGEF12 TIAM2 ARHGEF40 ARHGEF4

5.62e-04701014PF00621
DomainDH_2

ARHGEF12 TIAM2 ARHGEF40 ARHGEF4

5.62e-04701014PS50010
DomainDH-domain

ARHGEF12 TIAM2 ARHGEF40 ARHGEF4

5.93e-04711014IPR000219
Domain-

ARHGEF12 TIAM2 ARHGEF40 ARHGEF4

5.93e-047110141.20.900.10
DomainSomatotropin

ZFHX4 PRL

5.97e-0471012IPR001400
DomainGDS_CDC24_CS

ARHGEF12 TIAM2 ARHGEF4

1.22e-03391013IPR001331
DomainDUF4599

SPATA31D4 SPATA31D3

1.84e-03121012PF15371
DomainDUF4599

SPATA31D4 SPATA31D3

1.84e-03121012IPR027970
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH6

2.53e-03141012IPR011704
DomainAAA_5

DYNC2H1 DNAH6

2.53e-03141012PF07728
DomainPH

DOCK9 ARHGEF12 TIAM2 ARHGEF40 CADPS ARHGEF4

4.01e-032781016SM00233
DomainPH_DOMAIN

DOCK9 ARHGEF12 TIAM2 ARHGEF40 CADPS ARHGEF4

4.08e-032791016PS50003
DomainPH_domain

DOCK9 ARHGEF12 TIAM2 ARHGEF40 CADPS ARHGEF4

4.16e-032801016IPR001849
Pubmed

Linkage of loci associated with two pigment mutations on mouse chromosome 13.

AP3B1 LYST PRL

8.75e-07710331682216
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

CUL4B RMND5B NAA15 DSP DDX42 SMC4 NAP1L4 VPS16 AP3B1 PPP4R3A CYFIP1 MSMO1 DNAH6

1.38e-068471031335235311
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CUL4B USP34 DOCK9 LRCH1 XPO5 CADPS ARHGEF4

5.05e-06225103712168954
Pubmed

Optimal bone fracture repair requires 24R,25-dihydroxyvitamin D3 and its effector molecule FAM57B2.

TLCD3B CYP24A1

8.69e-062103230010626
Pubmed

Retinopretectal and accessory optic projections of normal mice and the OKN-defective mutant mice beige, beige-J, and pearl.

AP3B1 LYST

8.69e-06210323584547
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DYNC2H1 DNAH7 DNAH6

8.97e-061410339373155
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK9 DDX42 SMC4 ARHGEF12 LRCH1 TIAM2 LRCH3 ARHGEF40 CYFIP1 FBXO28 ARHGEF4 BUB3

1.76e-059161031232203420
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

USP34 RMND5B BAZ2B NAP1L4 ZFHX4 XPO5 MSL3

2.18e-05282103723667531
Pubmed

Analysis of the desmoplakin gene reveals striking conservation with other members of the plakin family of cytolinkers.

DSP PRL

2.60e-053103210597135
Pubmed

Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.

OR2A7 OR2A4

2.60e-053103227315375
Pubmed

De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation.

KAT8 MSL3

2.60e-053103230224647
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 NAA15 SMC4 NAP1L4 AP3B1 PPP4R3A CYFIP1 TMTC3 XPO5 PREP NGLY1 MAPK9

3.21e-059741031228675297
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

DOCK9 ARHGEF12 LRCH1 LRCH3 ARHGEF40

3.66e-05125103529467281
Pubmed

A zonal organization of odorant receptor gene expression in the olfactory epithelium.

OR2A7 OR2A4

5.19e-05410327683976
Pubmed

Behavioral abnormalities observed in Zfhx2-deficient mice.

ZFHX4 ZFHX2

5.19e-054103223300874
Pubmed

Structural basis for MOF and MSL3 recruitment into the dosage compensation complex by MSL1.

KAT8 MSL3

5.19e-054103221217699
Pubmed

The alveolar epithelium determines susceptibility to lung fibrosis in Hermansky-Pudlak syndrome.

AP3B1 LYST

5.19e-054103223043085
Pubmed

Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability.

KAT8 MSL3

5.19e-054103233837287
Pubmed

LRCH proteins: a novel family of cytoskeletal regulators.

LRCH1 LRCH3

5.19e-054103220805893
Pubmed

Tagging genes with cassette-exchange sites.

ZFAT NAA15 DOCK9 ARHGEF12 AP3B1 RINT1 XPO5

6.49e-05335103715741177
Pubmed

Sandy: a new mouse model for platelet storage pool deficiency.

AP3B1 LYST

8.64e-05510321936982
Pubmed

Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replication.

KAT6A KAT8

8.64e-055103217182677
Pubmed

MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2.

KAT6A KAT8

8.64e-055103211965546
Pubmed

Mesenchymal dysplasia: a recessive mutation on chromosome 13 of the mouse.

AP3B1 LYST

8.64e-05510328830098
Pubmed

Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.

DNAH7 DNAH6

8.64e-055103239056782
Pubmed

Molecular double clips within RepID WD40 domain control chromatin binding and CRL4-substrate assembly.

CUL4B BUB3

8.64e-055103234171797
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CUL4B NAA15 SMC4 NAP1L4 AP3B1 PPP4R3A CYFIP1 XPO5 BUB3

1.21e-04638103933239621
Pubmed

Muted, a new mutant affecting coat colour and otoliths of the mouse, and its position in linkage group XIV.

AP3B1 LYST

1.29e-04610325367369
Pubmed

FBXO28 promotes proliferation, invasion, and metastasis of pancreatic cancer cells through regulation of SMARCC2 ubiquitination.

IFT27 FBXO28

1.29e-046103237348029
Pubmed

The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1.

AP3B1 BUB3

1.29e-046103212419313
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CUL4B RMND5B IFT27 DYNC2H1 SMC4 AP3B1 PPP4R3A LRCH3 TBC1D32 CYFIP1 XPO5 BUB3 CHST3

1.45e-0413211031327173435
Pubmed

Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein.

KAT6A KAT8

1.81e-047103211742995
Pubmed

Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.

ARHGEF12 TIAM2 ARHGEF4

1.97e-0438103311756498
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK9 ARHGEF12 XPO5 CADPS FBXO28 TLE4 ARHGEF4

2.16e-04407103712693553
Pubmed

Saturation mutagenesis defines novel mouse models of severe spine deformity.

OR2A7 OR2A4

2.40e-048103234142127
Pubmed

Biosynthesis of chondroitin sulphate by a Golgi-apparatus-enriched preparation from cultures of mouse mastocytoma cells.

CSGALNACT2 CHST3

2.40e-04810326781479
Pubmed

NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.

ARHGEF12 TIAM2 ARHGEF4

2.86e-0443103312376548
Pubmed

Confirmed rare copy number variants implicate novel genes in schizophrenia.

PDE10A CYFIP1

3.08e-049103220298200
Pubmed

Survival and lung pathology of mouse models of Hermansky-Pudlak syndrome and Chediak-Higashi syndrome.

AP3B1 LYST

3.08e-049103210193444
Pubmed

Sak kinase gene structure and transcriptional regulation.

LYST PRL

3.08e-049103210607900
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

DSP DDX42 SMC4 PDE10A LYST SFMBT2 PPP4R4 RINT1 CAPRIN2 NGLY1 ARHGEF4 DNAH6 MYBPC1

3.39e-0414421031335575683
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DSP SMC4 ARHGEF40 TMTC3 XPO5

3.47e-04202103533005030
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 DSP DYNC2H1 CNTLN PPP4R3A CYFIP1 MAPK9 NCK2

3.71e-04588103838580884
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

VPS16 CNTLN ZFHX4 BUB3 PRL PARP12

3.79e-04318103616919269
Pubmed

A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16.

KAT8 MSL3

3.85e-0410103216227571
Pubmed

Acetylation of HIV-1 integrase by p300 regulates viral integration.

KAT6A KAT8

4.69e-0411103216096645
Pubmed

SMC5/6 is required for the formation of segregation-competent bivalent chromosomes during meiosis I in mouse oocytes.

SMC4 MLH1

5.62e-0412103228302748
Pubmed

Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.

KAT8 MSL3

5.62e-0412103223210685
Pubmed

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex.

KAT8 MSL3

5.62e-0412103220018852
Pubmed

H2B ubiquitylation promotes RNA Pol II processivity via PAF1 and pTEFb.

KAT8 MSL3

5.62e-0412103224837678
Pubmed

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.

USP34 DOCK9 CADPS CTNND2

5.84e-04128103430995482
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

DYNC2H1 AP3B1 DNAH7 PPP4R4 TBC1D32 CYFIP1 TMTC3 CTNND2

6.34e-04638103831182584
Pubmed

Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

ZFAT RANBP3L

6.63e-0413103221626137
Pubmed

MOF-associated complexes ensure stem cell identity and Xist repression.

KAT8 MSL3

6.63e-0413103224842875
Pubmed

Assessment of splice variant-specific functions of desmocollin 1 in the skin.

DSP RPTN

6.63e-0413103214673151
Pubmed

Evolution of odorant receptors expressed in mammalian testes.

OR2A7 OR2A4

6.63e-0413103211014824
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

DDX42 NAP1L4 AP3B1 PPP4R3A CYFIP1 XPO5 CADPS

7.19e-04498103736634849
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CUL4B USP34 NAA15 DSP DDX42 SMC4 XPO5 PREP

7.37e-04653103822586326
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

USP34 DOCK9 SMC4 FRMD4B BUB3 PRL

7.58e-04363103614691545
Pubmed

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

ARHGEF12 TIAM2 ARHGEF4

7.64e-0460103312787561
Pubmed

Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.

DOCK9 HUNK CTNND2

7.64e-0460103322889411
Pubmed

Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.

OR2A7 OR2A4

7.72e-041410327528109
Pubmed

Mutations in mice that influence natural killer (NK) cell activity.

AP3B1 LYST

7.72e-041410326971254
Pubmed

Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis.

DSP RPTN

7.72e-0414103227551807
Pubmed

Platelet storage pool deficiency in mouse pigment mutations associated with seven distinct genetic loci.

AP3B1 LYST

8.89e-041510326696991
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

ZNF280C CNTLN ZNF182 TMEM132D TTC29 MSL3 ZFHX2 CHST3

9.03e-04674103837196079
Pubmed

Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1.

DOCK9 LRCH1 BUB3

9.64e-0465103318729074
Pubmed

Elevated fibroblast growth factor 23 exerts its effects on placenta and regulates vitamin D metabolism in pregnancy of Hyp mice.

CYP24A1 SLC34A2

1.01e-0316103224470103
Pubmed

Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis.

MED31 MLH1

1.01e-0316103217696610
Pubmed

Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.

DOCK9 NAP1L4 SFMBT2 PREP PRL

1.07e-0325910359811942
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

PIK3C2G MAPK9

1.15e-0317103212960231
Pubmed

Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.

DNHD1 ARHGEF40

1.15e-0317103212693554
Pubmed

MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair.

KAT8 MSL3

1.15e-0317103220479123
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

DSP SMC4 NAP1L4 LRCH1 CYFIP1 BUB3

1.23e-03399103637536630
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DSP SMC4 HLCS ARHGEF12 AP3B1 CYFIP1 XPO5 NCK2

1.24e-03708103839231216
Pubmed

PEG3 control on the mammalian MSL complex.

KAT8 MSL3

1.29e-0318103228609438
Pubmed

TCF and Groucho-related genes influence pituitary growth and development.

TLE4 PRL

1.29e-0318103212907761
Pubmed

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.

THEMIS TMEM132D

1.29e-0318103223534349
Pubmed

Identification of host proteins required for HIV infection through a functional genomic screen.

ARHGEF12 TIAM2 ZNF182 RPTN NGLY1

1.32e-03272103518187620
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

CUL4B SMC4 VPS16 AP3B1 PPP4R3A CYFIP1 XPO5

1.42e-03560103735241646
Pubmed

Genome-wide association with bone mass and geometry in the Framingham Heart Study.

FRMD4B RBMS3

1.44e-0319103217903296
Pubmed

Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.

LYST TLE4

1.44e-031910329070936
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

EPHB4 USP34 LYST ARHGEF40 CYFIP1 MSMO1 BUB3 MAPK9 NCK2

1.55e-03910103936736316
Pubmed

The RepID-CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation.

CUL4B BUB3

1.59e-0320103231911655
Pubmed

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.

THEMIS NAP1L4

1.59e-0320103231591574
Pubmed

PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.

PPP4R4 PPP4R3A

1.59e-0320103218715871
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 USP34 DOCK9 KAT6A LYST TIAM2 ARHGEF40 TXNRD3 ARHGEF4 NCK2

1.65e-0311051031035748872
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

EPHB4 DOCK9 ZNF280C NAP1L4 PPP4R3A RBMS3 MSL3 MLH1 ZNF506

1.73e-03925103928986522
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DSP DDX42 SMC4 AP3B1 XPO5 MLH1 BUB3

1.76e-03582103720467437
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

NAA15 DSP ZNF280C DDX42 NAP1L4 HLCS PPP4R3A MLH1 PARP12

1.85e-03934103933916271
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

EPHB4 NAA15 DYNC2H1 SMC4 AP3B1 RINT1 ARHGEF40 TMTC3 XPO5

1.96e-03942103931073040
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

DSP DOCK9 SMC4 NAP1L4 MRPS18C AP3B1 DNAH7 NSUN3 XPO5 RBMS3

2.25e-0311531031029845934
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

CUL4B NAA15 NAP1L4 AP3B1 TLE4 ZNF506

2.28e-03451103636168627
Pubmed

HBO1 is required for H3K14 acetylation and normal transcriptional activity during embryonic development.

KAT6A KAT8

2.30e-0324103221149574
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNHD1 DYNC2H1 ARHGEF12 DNAH6

2.36e-03187103426460568
Pubmed

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.

ZFAT VPS16 LYST TAS2R4 MSMO1 PRL

2.44e-03457103632968282
Pubmed

Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18.

DSP RPTN

2.49e-0325103223132931
Pubmed

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

IFT27 DYNC2H1

2.49e-0325103227340223
Pubmed

Genomic evolution of the placenta using co-option and duplication and divergence.

NAA15 PRL

2.69e-0326103218340042
Pubmed

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

PDE10A PIK3C2G

2.90e-0327103211156964
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF12 TIAM2 ARHGEF40 ARHGEF4

1.71e-0466764722
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 ZFHX2

1.77e-0315762529
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

KAT6A KAT8

2.01e-031676266
GeneFamilyDyneins, axonemal

DNAH7 DNAH6

2.28e-0317762536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

KAT6A KAT8

2.28e-0317762486
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 ARHGEF12 SLC34A2 DNAH7 TTC29 DNAH6

3.60e-071951037fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 ARHGEF12 SLC34A2 DNAH7 TTC29 DNAH6

3.60e-071951037eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

2.72e-061691036fba841664939c771881ba97f14ef1df6635c04ff
ToppCelldroplet-Lung-nan-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP SLC34A2 ZFHX4 CAPRIN2 TXNRD3 CTNND2

4.17e-061821036cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCelldroplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP SLC34A2 ZFHX4 CAPRIN2 TXNRD3 CTNND2

4.17e-061821036d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCelldroplet-Lung-nan-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSP SLC34A2 ZFHX4 CAPRIN2 TXNRD3 CTNND2

4.17e-0618210367e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

4.58e-0618510365e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 ZFHX2 CFAP57 DNAH6

4.58e-06185103630f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

5.50e-0619110361c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DYNC2H1 SLC34A2 DNAH7 MSMO1 DNAH6

5.83e-061931036bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

IFT27 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

5.83e-061931036a0baa8be6f590b2031fede22be588715ae458e93
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

IFT27 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

6.01e-061941036c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

6.01e-0619410361ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

6.01e-0619410364a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 SLC34A2 DNAH7 TTC29 DNAH6

6.37e-06196103687d9881cfec461a5d89b688a83749b618c519485
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

6.56e-0619710366865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

6.56e-06197103671fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 DYNC2H1 DNAH7 ZFHX2 CFAP57 DNAH6

6.56e-06197103674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP47 TLCD3B PATE2 DNAH7 ZFHX2 DNAH6

6.56e-0619710366e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 IFT27 DYNC2H1 DNAH7 TTC29 DNAH6

7.15e-062001036cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 IFT27 DYNC2H1 DNAH7 TTC29 DNAH6

7.15e-06200103679e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

7.15e-0620010366a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFAP47 DNAH7 PPP4R4 ZFHX4 RANBP3L MYBPC1

7.15e-06200103607d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CFAP47 DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

7.15e-062001036bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP47 IFT27 DYNC2H1 DNAH7 TTC29 DNAH6

7.15e-062001036873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

CFAP47 DSP DNAH7 TTC29 DNAH6

2.68e-0515110358216462e723fec2797387929dde095370947e10a
ToppCellnormal_Lung-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

TLCD3B DOCK9 DNAH7 ARHGEF4 CLEC10A

3.64e-051611035283012858e575c70d09950de53da041509f59bfa
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

THEMIS TMEM132D CADPS ARHGEF4 CTNND2

3.86e-05163103519c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 TTC29 CTNND2 DNAH6

4.09e-0516510350c714e852f912b5749de4cb0895406673979b2e6
ToppCellPCW_07-8.5-Epithelial-Epithelial_ciliated|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 TTC29 CTNND2 DNAH6

4.09e-05165103582530f96aaefe28a13bad0474bbad043f127a86c
ToppCell3'_v3-GI_small-bowel-Mast-Mast_cell_granulo-myelo|GI_small-bowel / Manually curated celltypes from each tissue

CTTNBP2 CNTLN TIAM2 ARHGEF40 CADPS

4.98e-0517210353df11aefc09762fd1f94441324551178e030b249
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DSP SLC34A2 PREP RPTN CTNND2

5.41e-051751035442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DSP SLC34A2 PREP RPTN CTNND2

5.41e-05175103535fb7735dd3355476fe60404833cb60bd066bcf1
ToppCellCiliated_cells-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

5.56e-0517610351c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

6.34e-051811035dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

6.51e-0518210357ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

6.51e-051821035fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

DSP SLC34A2 MSMO1 RBMS3 ARHGEF4

6.68e-051831035dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HUNK FRMD4B SFMBT2 RBMS3 TTC29

6.86e-0518410357f6c8912677764d438ab0555faca344d74c2f483
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

6.86e-0518410355daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.04e-05185103518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.22e-051861035f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTTNBP2 DOCK9 PDE10A LRCH1 TIAM2

7.22e-0518610352d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

7.22e-05186103576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.22e-05186103585787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)|390C / Donor, Lineage, Cell class and subclass (all cells)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.22e-051861035708c5edefe36c91df27cf53c1b5101fb2030cc5a
ToppCell390C-Epithelial_cells-Epithelial-F_(Ciliated)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.22e-051861035029390c4aaf64e6bcd86124cd4a6dd2e6f3a374b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

USP34 ARHGEF12 LRCH1 NSUN3 FBXO28

7.22e-05186103503db813598b67b1e08f759758a1c2023396921fa
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.40e-051871035f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.40e-0518710359e10ed56090d82589bc457788282f664b70ace4b
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.59e-05188103526326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.59e-05188103561a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KAT6A GCNT4 SFMBT2 CACNA1I NCK2

7.59e-051881035939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.59e-05188103534b11f72ca73153d02edcd09b38983ad1a504659
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.59e-0518810352b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

THEMIS DOCK9 NAP1L4 GCNT4 CACNA1I

7.78e-0518910359ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-myeloid|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CTTNBP2 CNTLN MS4A4E CADPS CLEC10A

7.78e-0518910352aebea7a6c2f83112d7c504b742f2c04b92e459a
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.78e-05189103568a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 HUNK DNAH7 TMEM132D DNAH6

7.78e-051891035904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.78e-051891035b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

7.78e-05189103527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

7.78e-0518910353e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

7.98e-0519010359ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

7.98e-051901035833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TLCD3B DYNC2H1 PATE2 CNTLN DNAH7

7.98e-051901035250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|356C / Donor, Lineage, Cell class and subclass (all cells)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

8.18e-0519110358a5a2188b13ef4bbfd626a42565566708a751c1b
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 PPP4R4 TMEM132D CTNND2

8.18e-05191103560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CFAP47 SLC34A2 DNAH7 TTC29 CFAP57

8.18e-051911035ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)|356C / Donor, Lineage, Cell class and subclass (all cells)

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

8.18e-051911035e314dd8f1a841cab847ae3703bedfe1bc623ac61
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

8.18e-051911035e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

8.18e-0519110359d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CFAP47 SLC34A2 DNAH7 TTC29 CFAP57

8.18e-0519110356228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellmulticiliated|World / shred by cell class for turbinate

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

8.38e-0519210350f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

8.38e-051921035d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

8.38e-051921035354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellCOVID-19_Moderate-CD4+_T_activated|World / disease group, cell group and cell class

THEMIS DOCK9 GCNT4 NCK2 PARP12

8.59e-051931035c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

8.59e-051931035e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

8.59e-0519310350e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP47 CYP24A1 SLC34A2 DNAH7 TMEM132D

8.59e-051931035ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAZ2B DOCK9 KAT6A TLE4 CTNND2

8.59e-051931035aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP47 DYNC2H1 DNAH7 CFAP57 DNAH6

8.59e-051931035ea345d34440b25f65358a53dc72831998d1c3620
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAZ2B DOCK9 KAT6A TLE4 CTNND2

8.59e-051931035c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

8.59e-051931035ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

DOCK9 SLC34A2 FRMD4B PPP4R4 MSMO1

8.59e-051931035738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BAZ2B DOCK9 ARHGEF12 SFMBT2 CTNND2

8.80e-0519410350b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

8.80e-051941035958e648138676d46698090b4046cb484083ae449
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 PPP4R4 TMEM132D CTNND2

8.80e-0519410356b286992d4bb56013c0ea5a7601d3476d806175a
ToppCellwk_15-18-Epithelial-Proximal_epithelial|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

8.80e-051941035b0477583301dc6d9767b667bd2f8f94fbfaa6f81
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DSP DNAH7 TMEM132D CTNND2

8.80e-051941035f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

8.80e-05194103543be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

9.01e-051951035d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT27 DYNC2H1 DNAH7 TTC29 DNAH6

9.01e-0519510350fbba312e9ba9b70b4b814b67b6eb1f6544aaf6d
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

CFAP47 DYNC2H1 DNAH7 TTC29 DNAH6

9.01e-05195103521dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Ciliated|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFAP47 DNAH7 TTC29 CFAP57 DNAH6

9.01e-051951035cfcf554b436083179dea1d6fd6e3a800ea2430fe
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

9.01e-05195103534e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

9.01e-0519510353486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

9.01e-051951035e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

9.01e-05195103507a6bcef6af93ed87df455dee624037cb75e011a
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DYNC2H1 DNAH7 TTC29 CFAP57 DNAH6

9.01e-051951035e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38|World / Primary Cells by Cluster

TLCD3B BAZ2B HUNK FRMD4B ZFHX4

9.23e-05196103538da0751941adca650fe9b383d9f343153978eb5
Diseaseforced expiratory volume, response to bronchodilator

ZFAT CYP24A1 SLC34A2 PPP4R4 RBMS3 TTC29 TXNRD3 CLEC10A

9.72e-05445958EFO_0004314, GO_0097366
Diseasecortical surface area measurement

USP34 CTTNBP2 BAZ2B DOCK9 ARHGEF12 CNTLN LRCH1 DNAH7 FRMD4B PPP4R3A CSGALNACT2 CADPS TLE4 MLH1

1.01e-0413459514EFO_0010736
DiseaseVACTERL association (implicated_via_orthology)

DYNC2H1 TBC1D32

1.53e-046952DOID:14679 (implicated_via_orthology)
Diseasesusceptibility to measles measurement

HUNK CTNND2 NCK2

5.35e-0449953EFO_0008414
Diseasecolorectal cancer (is_implicated_in)

CYP24A1 XPO5 MLH1 MAPK9

6.42e-04121954DOID:9256 (is_implicated_in)
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

AP3B1 LYST

1.05e-0315952DOID:2223 (implicated_via_orthology)
Diseasebody surface area

TLCD3B ZFAT ARHGEF12 AP3B1 TIAM2 ARHGEF40 NSUN3 MAPK9

1.12e-03643958EFO_0022196
DiseaseFeeding difficulties

KAT8 MSL3

1.52e-0318952C0232466
Diseaseresponse to methotrexate, juvenile idiopathic arthritis

CTTNBP2 CACNA1I

1.69e-0319952EFO_0002609, GO_0031427
Diseasebehavioural disinhibition measurement

CTTNBP2 TMEM132D CACNA1I

1.85e-0375953EFO_0006946
Diseaseschizophrenia (is_implicated_in)

CYFIP1 CACNA1I CTNND2

2.07e-0378953DOID:5419 (is_implicated_in)
DiseaseQRS duration, response to sulfonylurea

DOCK9 CNTLN

2.48e-0323952EFO_0005055, EFO_0007922
Diseaseairway responsiveness measurement

LRCH3 CAPRIN2

2.70e-0324952EFO_0006897
DiseaseTEMPS-A questionnaire

ZFAT DYNC2H1

2.93e-0325952EFO_0004783
Diseaseplatelet component distribution width

EPHB4 DOCK9 NAP1L4 LRCH1 CYFIP1 MLH1 NCK2 MYBPC1

3.05e-03755958EFO_0007984
Diseasecortical thickness

CTTNBP2 DOCK9 ARHGEF12 LRCH1 FRMD4B PPP4R3A ARHGEF40 XPO5 CADPS CFAP57

3.11e-0311139510EFO_0004840
Diseaseresponse to methotrexate, drug-induced liver injury

ARHGEF12 RBMS3

3.17e-0326952EFO_0004228, GO_0031427

Protein segments in the cluster

PeptideGeneStartEntry
KHLLAKVQQEACAQY

ARHGEF40

56

Q8TER5
QKLYNELHICFETTK

CNTLN

381

Q9NXG0
YICIAVFKHLQQDIL

TBC1D32

1191

Q96NH3
KQIQKHLDYITQACL

BAZ2B

1746

Q9UIF8
FFLFDHQLIYCKKDL

ARHGEF4

521

Q9NR80
FKCHRLKENNIEQIY

BUB3

221

O43684
KLLYKQQLEECRHQE

DNHD1

3186

Q96M86
AAYLQHLCFGDNKIK

CTNND2

571

Q9UQB3
KKAADHCRQILNYVN

ARHGEF12

961

Q9NZN5
LIHKNYRKLCNLLVD

AP3B1

221

O00203
LKHKQSCAVENFYIL

PATE2

51

Q6UY27
EKCEVVIQHFNGKYL

RBMS3

191

Q6XE24
CANYLVKDLIAEILH

PIK3C2G

306

O75747
NEGYIKKLLELFHVC

PPP4R3A

166

Q6IN85
KCFKVLLFNHFCIQL

MSMO1

96

Q15800
LGIKKFEHQLLYNAC

CADPS

281

Q9ULU8
VLDFCYHLLKVQKHD

CYFIP1

1176

Q7L576
YRELVLLKCVNHKNI

MAPK9

71

P45984
KQLQVRCAHIEAKFY

NAP1L4

71

Q99733
QICKVVLDHFEKQYS

NSUN3

16

Q9H649
VHIFKYLNIQACKIA

LRCH3

266

Q96II8
NEKISKQLHLCYNIV

NGLY1

486

Q96IV0
KHFKVQLVDNVYCIG

NCK2

331

O43639
HLFYKKCAQLTVNLT

EPHB4

191

P54760
HKIYCQNLCLLAKLF

KAT8

256

Q9H7Z6
KRFKTDLHNCVAYIQ

CFAP57

1051

Q96MR6
YEHFRKELVNAQCAK

MED31

81

Q9Y3C7
ICINDLITEYNKQHK

HLCS

611

P50747
QIHAECKRFGKAYNL

DDX42

341

Q86XP3
FHLCKILKYEVDLND

KIAA1586

656

Q9HCI6
RCALFQVDHKNKELY

PDE10A

286

Q9Y233
NVHYIPAEKNVDLCK

MSL3

241

Q8N5Y2
VHIFKYLSIQACQIK

LRCH1

281

Q9Y2L9
LYELLKCNHNIKEAI

MIER3

251

Q7Z3K6
QKIYHFFCEILAVLK

OR2A7

171

Q96R45
LCKLVLAVDHYNIFS

NPBWR2

116

P48146
NALFKRILRCYEHKQ

NAA15

11

Q9BXJ9
QKIYHFFCEILAVLK

OR2A4

171

O95047
FQKQCIKLHICQYFL

PARP12

171

Q9H0J9
IKLHICQYFLQGECK

PARP12

176

Q9H0J9
IVVVLCLYFKIHNAL

FAM24B

16

Q8N5W8
QRYIKELCNLFEAHK

MOGAT2

306

Q3SYC2
ELCNLFEAHKLKFNI

MOGAT2

311

Q3SYC2
SNFLVLCYLHDVKNI

PREP

346

P48147
KSVILECLYHQNDKQ

KAT6A

696

Q92794
LFFLNAKACVHKGQI

FRMD4B

156

Q9Y2L6
CKQAIILKQVAHFYN

DYNC2H1

611

Q8NCM8
CIHQDKKIHLTVVYF

CSGALNACT2

296

Q8N6G5
KCHTYTLQEFKAAQV

DNAH6

336

Q9C0G6
CLAKQFHQLYREKVE

IFT27

166

Q9BW83
KVFDVYLCFLQKHQS

DOCK9

1431

Q9BZ29
FLCDIYHQNRLSKKE

CYP24A1

301

Q07973
CYFKHTLQQKVFILF

GCNT4

6

Q9P109
SLQDYIVHQLALCLK

CTTNBP2

1131

Q8WZ74
FCYIKILHQLKRCQN

CCR8

216

P51685
EEIFQYVCHILRKAK

CACNA1I

436

Q9P0X4
KCIDVHLKENAAYFQ

DSP

366

P15924
KKLLYGLCFFHALVQ

DNAH7

3576

Q8WXX0
FLKVERYHNLCQKQV

FBXO28

106

Q9NVF7
ACHILAIYFLLNKKL

HUNK

371

P57058
YIENGLICLKHKIRN

CAPRIN2

121

Q6IMN6
IHQVLIKQKCIVGFY

LYST

1861

Q99698
VIHSYLCKGLQEKFF

MS4A4E

26

Q96PG1
FILHVFQGNALKLKC

CFAP47

931

Q6ZTR5
FTTQFLKLHCLQKLY

PRAMEF26

166

H0Y7S4
LYKQLRQICEDHIKA

CUL4B

256

Q13620
DNYLKLLKCRIIHNN

PRL

211

P01236
LNKLCLTVYQLHALQ

ROGDI

196

Q9GZN7
DQHLRFLEFYKKLCT

PPP4R4

331

Q6NUP7
INCVTFALKYRHKQV

TMEM132D

936

Q14C87
LNQKTHICYEAKFSI

TMEM217B

26

A0A494BZU4
LDIRCSYIHVKQIFK

PLCZ1

31

Q86YW0
SKCFEDHLEQKYVQL

SPATA31D4

486

Q6ZUB0
YSVKKCIFLLFINHR

MLH1

251

P40692
ILCGKHVDYKNVQLL

MRPS18C

66

Q9Y3D5
VLKQLFLCDLYVLEH

CHST3

191

Q7LGC8
EKYCQLKNAHLVVIN

CLEC10A

206

Q8IUN9
VTYKENIAKCQHIFV

SLC34A2

341

O95436
CFYHQKDIKLENLII

THEMIS

116

Q8N1K5
SKCFEDHLEQKYVQL

SPATA31D3

486

P0C874
GIHFKFCVENIRKYL

SENP5

666

Q96HI0
CKESFTQKNILLVHY

ZFHX4

1501

Q86UP3
CEKAFSQKSYLIIHQ

ZNF182

491

P17025
QLLYDCHICERKFKN

ZFAT

401

Q9P243
CKESFTQKNILLVHY

ZFHX2

1196

Q9C0A1
YSGFCANHIKVQKVL

TIAM2

1201

Q8IVF5
YFKHIKEACIVLNLN

RINT1

726

Q6NUQ1
HFVKLLKDIIICFLN

THAP9

831

Q9H5L6
LDKVLQKFLTYGQHC

RMND5B

11

Q96G75
FLQAQYHSLKLECEK

TLE4

41

Q04727
EHNVLKINCKLFIFN

RANBP3L

296

Q86VV4
QFCKHQELETLKDLY

VPS16

606

Q9H269
KLCHQIERVKVAFYA

SFMBT2

876

Q5VUG0
LVEKHYVFLKRLCQV

XPO5

311

Q9HAV4
LENEIFRKKNHVCQY

SMC4

311

Q9NTJ3
HFYERCFKIAQLIKI

TTC29

161

Q8NA56
FVCLGKILIQYKQQH

TLCD3B

171

Q71RH2
YAKIICNKFDHDRVI

TXNRD3

566

Q86VQ6
KCNVQFNLLDPLKYH

ZNF280C

241

Q8ND82
KEYKHLEIFNQVVCA

USP34

51

Q70CQ2
HNLCVVYFEEKDLLK

TMTC3

776

Q6ZXV5
LLVFQLVQACYHKLD

RPTN

76

Q6XPR3
QRKIFQCDEYVKFLH

ZNF506

141

Q5JVG8
LLNILYCVKITNFQH

TAS2R4

101

Q9NYW5
KIIDCGKAFYQNRHL

ZNF554

521

Q86TJ5
TKYIFEHKGCQRILF

MYBPC1

296

Q00872