Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transcription coactivator activity	TRERF1 NCOA2 NCOA3 NCOA6 TCF20 PPRC1 DTX1 HIPK2 ARID1A CREBBP KMT2D MRTFB SMARCC2	5.86e-08	303	125	13	GO:0003713
GeneOntologyMolecularFunction	transcription coregulator activity	TRERF1 NCOA2 NCOA3 NCOA6 TCF20 PPRC1 DTX1 HIPK2 ARID1A CREBBP PRDM8 KMT2D MRTFB SMARCC2 SPEN	2.40e-06	562	125	15	GO:0003712
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	DAB2IP TRERF1 NCOA2 NCOA3 NCOA6 TCF20 MAPT PPRC1 DTX1 FRS3 HIPK2 ARID1A CREBBP PRDM8 KMT2D MRTFB MDC1 HGS SYN1 SMARCC2 SPEN YTHDF2	2.87e-06	1160	125	22	GO:0030674
GeneOntologyMolecularFunction	molecular adaptor activity	DAB2IP TRERF1 NCOA2 NCOA3 NCOA6 TCF20 MAPT PPRC1 DTX1 FRS3 HIPK2 ARID1A CREBBP PRDM8 KMT2D MRTFB MDC1 HGS SYN1 SMARCC2 SPEN YTHDF2	3.32e-05	1356	125	22	GO:0060090
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	TRERF1 NCOA2 NCOA3 NCOA6 PPRC1	3.99e-05	61	125	5	GO:0030374
GeneOntologyMolecularFunction	transcription factor binding	TRERF1 NCOA2 NCOA3 NCOA6 PPRC1 PCLO SREBF1 HIPK2 ARID1A CREBBP BBS10 LATS1 ASCL1 BSN SPEN	7.42e-05	753	125	15	GO:0008134
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	NCOA3 NCOA6 CREBBP	2.93e-04	21	125	3	GO:0042975
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	TRERF1 NCOA2 NCOA3 NCOA6 HIPK2 ARID1A CREBBP BBS10 LATS1 SPEN	2.97e-04	417	125	10	GO:0061629
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	NCOA2 NCOA3 NCOA6 LATS1	3.38e-04	53	125	4	GO:0030331
GeneOntologyMolecularFunction	chromatin binding	NCOA2 NCOA3 NCOA6 SREBF1 ARID1A CREBBP GATAD2B YBX2 PRDM8 ASCL1 GLI3 SMARCC2 MRNIP	7.46e-04	739	125	13	GO:0003682
GeneOntologyMolecularFunction	structural constituent of presynaptic active zone	PCLO BSN	1.06e-03	8	125	2	GO:0098882
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2B KMT2D	1.06e-03	8	125	2	GO:0140945
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	TRERF1 NCOA2 NCOA3 NCOA6 HIPK2 ARID1A CREBBP BBS10 LATS1 ASCL1 SPEN	1.09e-03	582	125	11	GO:0140297
GeneOntologyMolecularFunction	nuclear receptor binding	TRERF1 NCOA2 NCOA3 NCOA6 ARID1A LATS1	1.16e-03	187	125	6	GO:0016922
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	NCOA2 NCOA3 NCOA6	1.24e-03	34	125	3	GO:0046966
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2B KMT2D	1.69e-03	10	125	2	GO:0140999
GeneOntologyMolecularFunction	transcription coregulator binding	TRERF1 PCLO SREBF1 CREBBP BSN	1.89e-03	140	125	5	GO:0001221
GeneOntologyBiologicalProcess	maternal-to-zygotic transition of gene expression	KMT2B TPRX2 TPRX1	4.19e-06	6	124	3	GO:0160021
GeneOntologyBiologicalProcess	synaptic vesicle clustering	SYN3 PCLO SYN1 BSN	8.37e-06	22	124	4	GO:0097091
GeneOntologyCellularComponent	nuclear protein-containing complex	TRERF1 NCOA2 NCOA3 NCOA6 KMT2B HUS1B CTC1 WDR33 SCAF8 HIPK2 E2F5 ARID1A CREBBP GATAD2B PRDM8 KMT2D ASCL1 SMARCC2 MRNIP BATF3	1.91e-04	1377	125	20	GO:0140513
GeneOntologyCellularComponent	transcription regulator complex	TRERF1 NCOA2 NCOA3 NCOA6 HIPK2 E2F5 CREBBP GATAD2B ASCL1 GLI3 BATF3 SPEN	2.43e-04	596	125	12	GO:0005667
HumanPheno	Early onset of sexual maturation	MIA3 MAGEL2 KMT2B CREBBP KMT2D GLI3 USP7 SPEN	4.74e-05	189	37	8	HP:0100000
HumanPheno	Sparse hair	KMT2B CTC1 MARS1 SREBF1 ARID1A CREBBP GATAD2B GSN KMT2D SMARCC2 CDH3	5.38e-05	383	37	11	HP:0008070
HumanPheno	Abnormality of the thyroid gland	MAGEL2 KMT2B MARS1 SREBF1 POMC CD55 ARID1A CREBBP BBS10 KMT2D GLI3 SMARCC2 SPEN	6.95e-05	548	37	13	HP:0000820
HumanPheno	Abnormality of hair density	KMT2B CTC1 MARS1 SREBF1 ARID1A CREBBP GATAD2B GSN KMT2D SMARCC2 CDH3	7.66e-05	398	37	11	HP:0011357
HumanPheno	Facial grimacing	CREBBP GATAD2B GLI3	9.60e-05	13	37	3	HP:0000273
Domain	Nuc_rcpt_coact	NCOA2 NCOA3 CREBBP	5.23e-06	6	121	3	IPR009110
Domain	DUF4927	NCOA2 NCOA3	4.16e-05	2	121	2	IPR032565
Domain	DUF4927	NCOA2 NCOA3	4.16e-05	2	121	2	PF16279
Domain	Znf_piccolo	PCLO BSN	4.16e-05	2	121	2	IPR008899
Domain	zf-piccolo	PCLO BSN	4.16e-05	2	121	2	PF05715
Domain	DUF1518	NCOA2 NCOA3	1.24e-04	3	121	2	PF07469
Domain	Nuc_rcpt_coact_Ncoa-typ	NCOA2 NCOA3	1.24e-04	3	121	2	IPR014920
Domain	SRC-1	NCOA2 NCOA3	1.24e-04	3	121	2	IPR014935
Domain	Synapsin_pre-ATP-grasp_dom	SYN3 SYN1	1.24e-04	3	121	2	IPR020897
Domain	Synapsin_ATP-bd_dom	SYN3 SYN1	1.24e-04	3	121	2	IPR020898
Domain	Src1_rcpt_coact	NCOA2 NCOA3	1.24e-04	3	121	2	IPR008955
Domain	Nuclear_rcpt_coactivator	NCOA2 NCOA3	1.24e-04	3	121	2	IPR017426
Domain	-	NCOA2 NCOA3	1.24e-04	3	121	2	4.10.630.10
Domain	SYNAPSIN_1	SYN3 SYN1	1.24e-04	3	121	2	PS00415
Domain	SYNAPSIN_2	SYN3 SYN1	1.24e-04	3	121	2	PS00416
Domain	DUF1518	NCOA2 NCOA3	1.24e-04	3	121	2	IPR010011
Domain	Synapsin_C	SYN3 SYN1	1.24e-04	3	121	2	PF02750
Domain	Synapsin_N	SYN3 SYN1	1.24e-04	3	121	2	PF10581
Domain	Synapsin_CS	SYN3 SYN1	1.24e-04	3	121	2	IPR019735
Domain	Synapsin_P_site	SYN3 SYN1	1.24e-04	3	121	2	IPR019736
Domain	DUF1518	NCOA2 NCOA3	1.24e-04	3	121	2	SM01151
Domain	Synapsin	SYN3 SYN1	1.24e-04	3	121	2	PF02078
Domain	SRC-1	NCOA2 NCOA3	1.24e-04	3	121	2	PF08832
Domain	Nuc_rec_co-act	NCOA2 NCOA3	1.24e-04	3	121	2	PF08815
Domain	Synapsin	SYN3 SYN1	1.24e-04	3	121	2	IPR001359
Domain	EPHD	KMT2B TCF20 KMT2D	3.73e-04	22	121	3	PS51805
Domain	Znf_FYVE_PHD	KMT2B TCF20 PCLO KMT2D HGS BSN	3.92e-04	147	121	6	IPR011011
Domain	FYrich_C	KMT2B KMT2D	4.11e-04	5	121	2	IPR003889
Domain	FYrich_N	KMT2B KMT2D	4.11e-04	5	121	2	IPR003888
Domain	NUT	NUTM2G NUTM2F	4.11e-04	5	121	2	IPR024310
Domain	NUT_N	NUTM2G NUTM2F	4.11e-04	5	121	2	IPR024309
Domain	FYRC	KMT2B KMT2D	4.11e-04	5	121	2	SM00542
Domain	FYRN	KMT2B KMT2D	4.11e-04	5	121	2	SM00541
Domain	NUT	NUTM2G NUTM2F	4.11e-04	5	121	2	PF12881
Domain	FYRN	KMT2B KMT2D	4.11e-04	5	121	2	PF05964
Domain	FYRC	KMT2B KMT2D	4.11e-04	5	121	2	PF05965
Domain	FYRC	KMT2B KMT2D	4.11e-04	5	121	2	PS51543
Domain	FYRN	KMT2B KMT2D	4.11e-04	5	121	2	PS51542
Domain	Retrov_capsid_C	PGBD1 ZSCAN25 MZF1 ERVK-5	5.79e-04	59	121	4	IPR008916
Domain	-	SYN3 SYN1	3.10e-03	13	121	2	3.40.50.20
Domain	SET	KMT2B PRDM8 KMT2D	3.29e-03	46	121	3	SM00317
Domain	PreATP-grasp_dom	SYN3 SYN1	3.60e-03	14	121	2	IPR016185
Domain	-	SYN3 SYN1	4.14e-03	15	121	2	3.30.1490.20
Domain	SET_dom	KMT2B PRDM8 KMT2D	4.16e-03	50	121	3	IPR001214
Domain	SET	KMT2B PRDM8 KMT2D	4.16e-03	50	121	3	PS50280
Domain	Post-SET_dom	KMT2B KMT2D	4.71e-03	16	121	2	IPR003616
Domain	PostSET	KMT2B KMT2D	4.71e-03	16	121	2	SM00508
Domain	POST_SET	KMT2B KMT2D	4.71e-03	16	121	2	PS50868
Domain	Kringle_CS	ROR1 MST1L	5.31e-03	17	121	2	IPR018056
Domain	KRINGLE_1	ROR1 MST1L	5.31e-03	17	121	2	PS00021
Domain	KR	ROR1 MST1L	5.31e-03	17	121	2	SM00130
Domain	Kringle	ROR1 MST1L	5.31e-03	17	121	2	IPR000001
Domain	KRINGLE_2	ROR1 MST1L	5.31e-03	17	121	2	PS50070
Domain	Kringle	ROR1 MST1L	5.31e-03	17	121	2	PF00051
Domain	-	NCOA2 NCOA3 SREBF1 ASCL1	5.53e-03	109	121	4	4.10.280.10
Domain	SCAN	PGBD1 ZSCAN25 MZF1	5.73e-03	56	121	3	SM00431
Domain	ATP_grasp_subdomain_1	SYN3 SYN1	5.95e-03	18	121	2	IPR013815
Domain	-	SYN3 SYN1	5.95e-03	18	121	2	3.30.470.20
Domain	SCAN_BOX	PGBD1 ZSCAN25 MZF1	6.32e-03	58	121	3	PS50804
Domain	SCAN	PGBD1 ZSCAN25 MZF1	6.32e-03	58	121	3	PF02023
Domain	SCAN_dom	PGBD1 ZSCAN25 MZF1	6.32e-03	58	121	3	IPR003309
Pathway	REACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA	TUT4 TPRX2 CREBBP TPRX1	3.79e-06	17	92	4	M48025
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	NCOA2 NCOA6 SREBF1 CREBBP	4.85e-06	18	92	4	M26942
Pathway	REACTOME_ADIPOGENESIS	NCOA2 NCOA3 NCOA6 SREBF1 CREBBP GATAD2B	8.14e-05	110	92	6	M48259
Pathway	REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP	NCOA2 NCOA6 SREBF1 CREBBP	1.57e-04	42	92	4	M27172
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	NCOA2 NCOA3 NCOA6 SREBF1 CREBBP	2.18e-04	84	92	5	M1008
Pathway	BIOCARTA_VDR_PATHWAY	NCOA3 ARID1A CREBBP	3.79e-04	22	92	3	MM1370
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	SYN3 APBA1 SYN1	4.33e-04	23	92	3	MM14852
Pathway	REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE	SYN3 APBA1 SYN1	4.33e-04	23	92	3	M12627
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS	NCOA2 NCOA6 PPRC1 CREBBP	4.49e-04	55	92	4	M27145
Pathway	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	NCOA2 NCOA6 SREBF1 CREBBP	4.49e-04	55	92	4	M27001
Pathway	BIOCARTA_VDR_PATHWAY	ARID1A CREBBP SMARCC2	4.93e-04	24	92	3	M13404
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 NCOA2 NCOA3 NCOA6 KMT2B TCF20 TPRX2 ARID1A CREBBP KMT2D RESF1 MDC1 TPRX1 SMARCC2 SPEN	4.51e-12	351	129	15	38297188
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA2 NCOA6 KMT2B TCF20 RPAP3 WDR33 PDLIM7 ARID1A CREBBP ZYX KMT2D MRTFB LATS1 MDC1 SEC23IP USP7 SPEN	2.55e-11	549	129	17	38280479
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	NCOA2 NRBP1 JCAD NCOA3 TCF20 PCLO ARID1A CREBBP GATAD2B KMT2D RESF1 USP7 SMARCC2 ZNF518B NUTM2F	2.66e-11	398	129	15	35016035
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	TRERF1 DOCK3 JCAD NCOA6 MAGEL2 PDLIM7 DTX1 TSC22D2 MRTFB LATS1 MDC1 USP7 BSN SPEN PLEKHA7	7.84e-11	430	129	15	35044719
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TRERF1 NCOA2 NCOA3 NCOA6 TCF20 WDR33 ARID1A CREBBP KMT2D MDC1 USP7 SMARCC2	4.03e-10	268	129	12	33640491
Pubmed	Human transcription factor protein interaction networks.	TRERF1 NCOA2 NCOA3 NCOA6 KMT2B TCF20 WDR33 SCAF8 MARS1 HIPK2 PUM2 ARID1A CREBBP GATAD2B KMT2D RESF1 GLI3 MDC1 HGS USP7 SMARCC2 SPEN CCDC86 YTHDF2	5.22e-10	1429	129	24	35140242
Pubmed	Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.	NCOA2 NCOA3 NCOA6 TCF20 ARID1A KMT2D SMARCC2 SPEN	5.42e-10	78	129	8	28611094
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 NCOA3 NCOA6 KMT2B TCF20 MAPT SCAF8 PUM2 ZYX GATAD2B KMT2D LATS1 NAF1 MDC1 USP7 SMARCC2 SPEN CCDC86	6.48e-10	774	129	18	15302935
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NCOA2 NCOA3 NCOA6 TCF20 WDR33 SCAF8 PUM2 ARID1A CREBBP KMT2D SEC23IP RAB5A YTHDF2	1.74e-08	457	129	13	32344865
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA2 NCOA3 NCOA6 TCF20 ARID1A KMT2D SPEN	2.69e-08	83	129	7	28794006
Pubmed	Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.	NCOA3 ARID1A CREBBP SMARCC2	5.84e-08	11	129	4	18003620
Pubmed	O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.	PCLO MRTFB SYN1 BSN	1.76e-07	14	129	4	16452088
Pubmed	Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.	NCOA2 NCOA6 CREBBP KMT2D	1.76e-07	14	129	4	12482968
Pubmed	Estrogen receptor-alpha interaction with the CREB binding protein coactivator is regulated by the cellular environment.	NCOA2 NCOA3 CREBBP	4.96e-07	5	129	3	14766010
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	NCOA6 TCF20 WDR33 ARID1A GATAD2B KMT2D MRTFB MDC1 SMARCC2 SPEN	6.31e-07	341	129	10	32971831
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MIA3 TCF20 PDLIM7 ROR1 ARID1A GLI3 HGS SEC23IP PLEKHA7	6.56e-07	263	129	9	34702444
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DAB2IP DOCK3 NCOA6 KMT2B CTC1 PPRC1 SREBF1 THAP8 ARID1A ARHGEF11 TESK1 SLC38A10 KMT2D NAPRT USP7 MAPKBP1 SPEN	7.58e-07	1105	129	17	35748872
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA2 JCAD ROBO4 NCOA3 NCOA6 TCF20 ARID1A CREBBP KMT2D SEC23IP SMARCC2 BSN SPEN	7.95e-07	638	129	13	31182584
Pubmed	T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.	NCOA2 NCOA3 NCOA6 CREBBP	8.36e-07	20	129	4	11877444
Pubmed	Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.	NCOA6 KMT2B KMT2D	9.89e-07	6	129	3	17021013
Pubmed	Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.	NCOA2 NCOA3 NCOA6 CREBBP	1.03e-06	21	129	4	19596656
Pubmed	BRCA1-IRIS regulates cyclin D1 expression in breast cancer cells.	NCOA2 NCOA3 CREBBP	1.73e-06	7	129	3	16860316
Pubmed	The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function.	NCOA2 NCOA3 CREBBP	1.73e-06	7	129	3	9192892
Pubmed	ASCOM controls farnesoid X receptor transactivation through its associated histone H3 lysine 4 methyltransferase activity.	NCOA6 KMT2B KMT2D	1.73e-06	7	129	3	19556342
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	NCOA2 NCOA3 TCF20 HIPK2 ARID1A GATAD2B KMT2D USP7	1.78e-06	220	129	8	35785414
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	NCOA6 KMT2B ARID1A CREBBP KMT2D SMARCC2 CDH3	2.11e-06	157	129	7	30186101
Pubmed	New nomenclature for chromatin-modifying enzymes.	NCOA2 NCOA3 KMT2B CREBBP KMT2D	2.33e-06	57	129	5	18022353
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	NCOA2 NCOA3 XIRP1 TCF20 RESF1 GLI3 BSN CCDC17	2.73e-06	233	129	8	37704626
Pubmed	Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.	NCOA2 NCOA3 CREBBP	2.75e-06	8	129	3	11971985
Pubmed	Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase.	NCOA2 NCOA3 CREBBP	2.75e-06	8	129	3	10490106
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DAB2IP SNPH TCF20 PPRC1 SCAF8 PUM2 TRIL SEL1L3 MAPKBP1 SPEN	3.08e-06	407	129	10	12693553
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TRERF1 NCOA2 NCOA3 NCOA6 KMT2B TCF20 MARS1 ARID1A CREBBP ZYX GATAD2B GSN KMT2D RESF1 SMARCC2 SPEN	3.50e-06	1103	129	16	34189442
Pubmed	The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.	ARID1A GLI3 SMARCC2	4.12e-06	9	129	3	37805104
Pubmed	Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.	KMT2B E2F5 KMT2D	4.12e-06	9	129	3	16951254
Pubmed	Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.	ARID1A MDC1 USP7 SMARCC2	4.59e-06	30	129	4	31043422
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	NCOA3 TCF20 WDR33 SCAF8 ARHGEF11 USP7 PLEKHA7	5.20e-06	180	129	7	35198878
Pubmed	The synaptic vesicle cycle.	SYN3 PCLO SYN1 BSN	5.26e-06	31	129	4	15217342
Pubmed	Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway.	NCOA3 CREBBP SMARCC2	5.87e-06	10	129	3	16751102
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	NCOA6 TCF20 ARID1A MRTFB RESF1 MDC1	6.90e-06	123	129	6	26912792
Pubmed	The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.	NCOA2 NCOA3 NCOA6	8.05e-06	11	129	3	36613751
Pubmed	Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.	NCOA2 NCOA3 POMC	8.05e-06	11	129	3	16109736
Pubmed	Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.	KMT2B CREBBP KMT2D	1.07e-05	12	129	3	17707229
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	TUT4 WDR33 SCAF8 ARID1A GATAD2B MDC1 SMARCC2	1.14e-05	203	129	7	22083510
Pubmed	Gamma-melanocyte stimulating hormone regulates the expression and cellular localization of epithelial sodium channel in inner medullary collecting duct cells.	POMC SCNN1A	1.37e-05	2	129	2	23871693
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	PCLO BSN	1.37e-05	2	129	2	23403927
Pubmed	Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro.	SREBF1 CREBBP	1.37e-05	2	129	2	9765204
Pubmed	Uterine Tumor Resembling Ovarian Sex Cord Tumor: A Distinct Entity Characterized by Recurrent NCOA2/3 Gene Fusions.	NCOA2 NCOA3	1.37e-05	2	129	2	30273195
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	PCLO BSN	1.37e-05	2	129	2	26793095
Pubmed	Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction.	MAPT HGS	1.37e-05	2	129	2	30166454
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	PCLO BSN	1.37e-05	2	129	2	20332206
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	1.37e-05	2	129	2	35640156
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	PCLO BSN	1.37e-05	2	129	2	21935939
Pubmed	Increased Epithelial Sodium Channel Activity Contributes to Hypertension Caused by Na+-HCO3- Cotransporter Electrogenic 2 Deficiency.	SCNN1A SLC4A5	1.37e-05	2	129	2	25941340
Pubmed	Role of tau N-terminal motif in the secretion of human tau by End Binding proteins.	MAPT MAPRE3	1.37e-05	2	129	2	30668577
Pubmed	A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.	CREBBP KMT2D	1.37e-05	2	129	2	27999180
Pubmed	Synapsin-1 and tau reciprocal O-GlcNAcylation and phosphorylation sites in mouse brain synaptosomes.	MAPT SYN1	1.37e-05	2	129	2	23807304
Pubmed	Effects of a Levonorgestrel-Releasing Intrauterine System on the Expression of Steroid Receptor Coregulators in Adenomyosis.	NCOA2 NCOA3	1.37e-05	2	129	2	26040939
Pubmed	USP7 inhibition inhibits proliferation and induces megakaryocytic differentiation in MDS cells by upregulating gelsolin.	GSN USP7	1.37e-05	2	129	2	32130729
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	PCLO BSN	1.37e-05	2	129	2	25652077
Pubmed	YBX2 modulates mRNA stability via interaction with YTHDF2 in endometrial cancer cells.	YBX2 YTHDF2	1.37e-05	2	129	2	37030331
Pubmed	CBP is required for sterol-regulated and sterol regulatory element-binding protein-regulated transcription.	SREBF1 CREBBP	1.37e-05	2	129	2	9651391
Pubmed	Quantifying Protection in Disordered Proteins Using Millisecond Hydrogen Exchange-Mass Spectrometry and Peptic Reference Peptides.	NCOA3 CREBBP	1.37e-05	2	129	2	28675294
Pubmed	Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis.	NCOA2 NCOA3	1.37e-05	2	129	2	21220509
Pubmed	YTHDF2 alleviates microglia activation via promoting circHIPK2 degradation.	HIPK2 YTHDF2	1.37e-05	2	129	2	38147784
Pubmed	Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor.	ZYX LATS1	1.37e-05	2	129	2	10831611
Pubmed	Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation.	MAPT CREBBP	1.37e-05	2	129	2	27383765
Pubmed	Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.	MAPT MAPRE3	1.37e-05	2	129	2	31542321
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2B KMT2D	1.37e-05	2	129	2	35506254
Pubmed	A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.	NCOA2 NCOA3	1.37e-05	2	129	2	30048685
Pubmed	Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin.	NCOA3 CREBBP	1.37e-05	2	129	2	21632823
Pubmed	Hybrid selection of transcribed sequences from microdissected DNA: isolation of genes within amplified region at 20q11-q13.2 in breast cancer.	NCOA3 NCOA6	1.37e-05	2	129	2	8758910
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	PCLO BSN	1.37e-05	2	129	2	27321892
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	PCLO BSN	1.37e-05	2	129	2	32493491
Pubmed	Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.	NCOA2 NCOA3 CREBBP	1.39e-05	13	129	3	11266503
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DAB2IP TRERF1 NCOA2 NCOA3 MIA3 TCF20 WDR81 ARHGEF11 GATAD2B GSN SEC23IP SYN1 SMARCC2 BSN	1.45e-05	963	129	14	28671696
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	ARID1A CREBBP USP7 SMARCC2	1.49e-05	40	129	4	34585037
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	PCLO SYN1 BSN	1.76e-05	14	129	3	21228161
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	KMT2B CRACR2A PDLIM7 SREBF1 ZYX HGS USP7 SMARCC2 ZNF488 MAPKBP1 SPEN	1.76e-05	608	129	11	16713569
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TRERF1 TCF20 PCLO RESF1 MDC1 USP7 SMARCC2 SPEN CCDC86	1.81e-05	396	129	9	26687479
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	MIA3 TUT4 TCF20 RPAP3 WDR33 SCAF8 PUM2 GATAD2B MDC1 HGS SEC23IP YTHDF2	1.94e-05	733	129	12	34672954
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DAB2IP DOCK3 JCAD MIA3 TUT4 SYN3 MAPT PCLO ACBD5 APBA1 OGDH GATAD2B USP7 SMARCC2 BSN	2.24e-05	1139	129	15	36417873
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	NCOA2 NCOA3 WDR33 PUM2 CREBBP RESF1	2.31e-05	152	129	6	38360978
Pubmed	H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation.	NCOA6 KMT2B KMT2D	2.69e-05	16	129	3	24368734
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 NCOA3 KMT2B TCF20 RPAP3 KMT2D MRTFB RESF1 SEC23IP	2.76e-05	418	129	9	34709266
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	NCOA6 OGDH KMT2D MDC1 USP7 SMARCC2 SLC4A5	2.84e-05	234	129	7	36243803
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	NCOA3 NCOA6 MIA3 TCF20 MAPT PCLO ARID1A CREBBP SMARCC2	3.14e-05	425	129	9	24999758
Pubmed	MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet β-Cell Function.	NCOA6 KMT2B KMT2D	3.26e-05	17	129	3	26180087
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	NCOA2 NCOA3 CREBBP	3.26e-05	17	129	3	19183483
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DOCK3 KMT2B DTX1 PCDHA11 EXTL1 ARHGEF11 SMARCC2 SPEN	3.33e-05	329	129	8	17474147
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOA2 EP400P1 MIA3 TUT4 MAPT SCAF8 MARS1 HIPK2 ARID1A OGDH CREBBP SGK2 MRTFB SEL1L3 SCNN1A SLC4A5 DOP1A	3.78e-05	1489	129	17	28611215
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	NCOA6 KMT2B KMT2D	3.91e-05	18	129	3	17500065
Pubmed	Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling.	KMT2B USP7 SPEN	3.91e-05	18	129	3	19640993
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	NCOA3 ARID1A GATAD2B KMT2D RESF1 SMARCC2	3.91e-05	167	129	6	20362541
Pubmed	Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.	CREBBP KMT2D	4.09e-05	3	129	2	34463256
Pubmed	Synapsin IIa controls the reserve pool of glutamatergic synaptic vesicles.	SYN3 SYN1	4.09e-05	3	129	2	18945891
Pubmed	Different presynaptic roles of synapsins at excitatory and inhibitory synapses.	SYN3 SYN1	4.09e-05	3	129	2	15601943
Pubmed	Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.	NCOA2 NCOA3	4.09e-05	3	129	2	16675958
Pubmed	Compensatory network alterations upon onset of epilepsy in synapsin triple knock-out mice.	SYN3 SYN1	4.09e-05	3	129	2	21621590
Pubmed	FLASH interacts with p160 coactivator subtypes and differentially suppresses transcriptional activity of steroid hormone receptors.	NCOA2 NCOA3	4.09e-05	3	129	2	15698540
Pubmed	Real-time imaging of Rab3a and Rab5a reveals differential roles in presynaptic function.	SYN1 RAB5A	4.09e-05	3	129	2	16141272
Interaction	ALG13 interactions	NCOA2 NCOA3 MIA3 TCF20 WDR33 SCAF8 PUM2 ARID1A ZYX KMT2D LATS1 MAPKBP1 YTHDF2	1.17e-10	183	125	13	int:ALG13
Interaction	SOX7 interactions	NCOA2 NCOA3 TCF20 ARID1A CREBBP KMT2D RESF1 SMARCC2 ZNF518B	2.03e-09	82	125	9	int:SOX7
Interaction	CREBBP interactions	TRERF1 NCOA2 NCOA3 NCOA6 MAPT SREBF1 HIPK2 TPRX2 E2F5 ARID1A CREBBP KMT2D LATS1 GLI3 MDC1 USP7 SMARCC2 YTHDF2	3.17e-08	599	125	18	int:CREBBP
Interaction	TBXT interactions	NCOA2 NCOA3 NCOA6 TCF20 ARID1A CREBBP KMT2D SMARCC2 SPEN	4.43e-08	116	125	9	int:TBXT
Interaction	TPRX2 interactions	NCOA2 NCOA6 TPRX2 ARID1A CREBBP KMT2D SMARCC2	5.37e-08	56	125	7	int:TPRX2
Interaction	ERG interactions	NCOA2 NCOA3 NCOA6 TCF20 HIPK2 ARID1A CREBBP KMT2D RESF1 SYN1 SMARCC2	1.46e-07	223	125	11	int:ERG
Interaction	SOX9 interactions	NCOA3 NCOA6 ARID1A CREBBP KMT2D USP7 SMARCC2 SPEN	1.59e-07	97	125	8	int:SOX9
Interaction	SP7 interactions	TRERF1 NCOA2 NCOA3 NCOA6 KMT2B TCF20 WDR33 SCAF8 ARID1A CREBBP KMT2D SMARCC2	4.31e-07	304	125	12	int:SP7
Interaction	EGR2 interactions	TRERF1 NCOA2 NCOA3 NCOA6 DTX1 ARID1A CREBBP KMT2D RESF1	1.22e-06	171	125	9	int:EGR2
Interaction	YAP1 interactions	TRERF1 JCAD NCOA6 KMT2B TCF20 RPAP3 WDR33 PDLIM7 MARS1 ARID1A OGDH CREBBP ZYX GSN KMT2D MRTFB LATS1 MDC1 USP7 SMARCC2 SPEN	3.64e-06	1095	125	21	int:YAP1
Interaction	SMG7 interactions	NCOA2 NCOA3 NCOA6 TCF20 SCAF8 ARID1A CREBBP ZYX KMT2D LATS1 YTHDF2	4.91e-06	319	125	11	int:SMG7
Interaction	HNF4A interactions	NCOA2 NCOA3 NCOA6 KMT2B SREBF1 ARID1A CREBBP KMT2D SMARCC2 SPEN	8.49e-06	275	125	10	int:HNF4A
Interaction	WWTR1 interactions	NCOA2 NCOA6 TCF20 RPAP3 PDLIM7 ARID1A CREBBP ZYX KMT2D LATS1 SEC23IP USP7	1.27e-05	422	125	12	int:WWTR1
Interaction	NUP35 interactions	NCOA2 NCOA3 NCOA6 TCF20 WDR33 SCAF8 PUM2 ARID1A CREBBP KMT2D SEC23IP YTHDF2	1.33e-05	424	125	12	int:NUP35
Interaction	ARID1B interactions	NCOA3 TPRX2 E2F5 ARID1A CREBBP MDC1 SMARCC2 BATF3	1.48e-05	177	125	8	int:ARID1B
Interaction	EP300 interactions	TRERF1 NCOA2 ROBO4 NCOA3 NCOA6 NRDC RPAP3 MAPT MARS1 DTX1 SREBF1 HIPK2 E2F5 ARID1A CREBBP ZYX KMT2D ASCL1 MDC1 USP7 SMARCC2 BSN NUTM2F	1.53e-05	1401	125	23	int:EP300
Interaction	SMAD1 interactions	NCOA6 TCF20 HIPK2 ARID1A CREBBP KMT2D MRTFB GLI3 HGS	2.11e-05	243	125	9	int:SMAD1
Interaction	SMAD3 interactions	NCOA3 NCOA6 KMT2B HIPK2 E2F5 ARID1A CREBBP GLI3 HGS USP7 SMARCC2 YTHDF2	2.24e-05	447	125	12	int:SMAD3
Interaction	TLE3 interactions	TRERF1 NCOA2 NCOA3 TCF20 SCAF8 TPRX2 ARID1A CREBBP KMT2D SMARCC2 SPEN	2.29e-05	376	125	11	int:TLE3
Interaction	ASF1A interactions	NCOA6 KMT2B TCF20 ARID1A GATAD2B KMT2D MDC1 SMARCC2 SPEN	2.56e-05	249	125	9	int:ASF1A
Interaction	POU4F1 interactions	HIPK2 MAPRE3 USP7	2.71e-05	10	125	3	int:POU4F1
Interaction	SOX17 interactions	NCOA2 NCOA3 NCOA6 TCF20 ARID1A KMT2D	2.79e-05	95	125	6	int:SOX17
Interaction	SMAD2 interactions	NCOA3 NCOA6 MAPT HIPK2 ARID1A CREBBP GATAD2B GLI3 HGS USP7 SMARCC2	2.84e-05	385	125	11	int:SMAD2
Interaction	CRX interactions	TRERF1 NCOA2 NCOA3 TCF20 ARID1A CREBBP KMT2D HGS SPEN	2.99e-05	254	125	9	int:CRX
Interaction	GATA2 interactions	NCOA3 NCOA6 MARS1 ARID1A CREBBP KMT2D USP7 SMARCC2	3.44e-05	199	125	8	int:GATA2
Interaction	KIAA1755 interactions	USP7 KIAA1755	3.82e-05	2	125	2	int:KIAA1755
Interaction	FEV interactions	NCOA2 NCOA3 NCOA6 KMT2B TCF20 ARID1A CREBBP KMT2D	3.97e-05	203	125	8	int:FEV
Interaction	AR interactions	TRERF1 NCOA2 NCOA3 NCOA6 TCF20 WDR33 SREBF1 HIPK2 ARID1A CREBBP GATAD2B GSN KMT2D GLI3 MDC1 USP7 SMARCC2 TNS4	4.06e-05	992	125	18	int:AR
Interaction	DTX2 interactions	NCOA3 TCF20 WDR33 SCAF8 DTX1 ARHGEF11 MDC1 HGS USP7 PLEKHA7	4.06e-05	330	125	10	int:DTX2
Interaction	GOLGA2 interactions	NCOA2 NCOA6 TCF20 CRACR2A SCAF8 ZYX GATAD2B MAPRE3 KMT2D LATS1 HGS SEC23IP TPRX1 ZNF488 CCDC17	4.95e-05	733	125	15	int:GOLGA2
Interaction	GCM1 interactions	NCOA3 ARID1A CREBBP KMT2D SMARCC2	6.46e-05	68	125	5	int:GCM1
Interaction	ETV4 interactions	NCOA2 NCOA3 ARID1A CREBBP KMT2D	6.93e-05	69	125	5	int:ETV4
Interaction	TGM7 interactions	FRS3 HGS SEC23IP TNXB	7.12e-05	36	125	4	int:TGM7
Interaction	E2F5 interactions	E2F5 ARID1A CREBBP KMT2D	7.12e-05	36	125	4	int:E2F5
Interaction	ITCH interactions	TRERF1 RPAP3 DTX1 ARID1A GSN LATS1 HGS SCNN1A SMARCC2 SPEN	7.66e-05	356	125	10	int:ITCH
Interaction	RBBP5 interactions	NCOA6 KMT2B WDR33 TPRX2 ARID1A CREBBP KMT2D SMARCC2 SPEN	7.69e-05	287	125	9	int:RBBP5
Interaction	KMT2D interactions	NCOA6 KMT2B TPRX2 E2F5 CREBBP KMT2D USP7	8.95e-05	169	125	7	int:KMT2D
Interaction	H2BC21 interactions	KMT2B TCF20 MARS1 PCLO HIPK2 ARID1A CREBBP GATAD2B MRTFB MDC1 USP7 SMARCC2 ZNF518B CCDC86	1.07e-04	696	125	14	int:H2BC21
Interaction	TRIL interactions	TRIL USP7	1.14e-04	3	125	2	int:TRIL
Interaction	SMARCC1 interactions	NCOA3 SREBF1 TPRX2 ARID1A CREBBP GATAD2B LATS1 MDC1 USP7 SMARCC2	1.42e-04	384	125	10	int:SMARCC1
Interaction	PAX9 interactions	NCOA2 NCOA3 NCOA6 TCF20 ARID1A KMT2D	1.61e-04	130	125	6	int:PAX9
Interaction	ZYX interactions	DOCK3 PDLIM7 HIPK2 TSC22D2 ZYX LATS1 HGS RAB5A YTHDF2	2.15e-04	329	125	9	int:ZYX
Interaction	KLF5 interactions	NCOA2 NCOA3 NCOA6 SREBF1 ARID1A CREBBP KMT2D	2.17e-04	195	125	7	int:KLF5
Interaction	MDM2 interactions	HUS1B MAPT PDLIM7 SREBF1 TP53I3 HIPK2 OGDH CREBBP GSN LATS1 RESF1 MDC1 USP7	2.28e-04	658	125	13	int:MDM2
Interaction	FOXI1 interactions	NCOA3 ARID1A CREBBP KMT2D HGS	2.71e-04	92	125	5	int:FOXI1
Interaction	PAGR1 interactions	NCOA6 KMT2B TPRX2 KMT2D	2.81e-04	51	125	4	int:PAGR1
Interaction	NCOA6 interactions	NCOA2 NCOA6 KMT2B TPRX2 CREBBP KMT2D	2.91e-04	145	125	6	int:NCOA6
Interaction	ZBTB7C interactions	SREBF1 GATAD2B USP7	3.29e-04	22	125	3	int:ZBTB7C
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	NCOA2 NCOA3 CREBBP	4.65e-05	17	76	3	486
GeneFamily	Synapsins	SYN3 SYN1	5.22e-05	3	76	2	1325
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2B PRDM8 KMT2D	3.89e-04	34	76	3	487
GeneFamily	Basic helix-loop-helix proteins	NCOA2 NCOA3 SREBF1 ASCL1	1.19e-03	110	76	4	420
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO BSN	1.77e-03	15	76	2	26
GeneFamily	PDZ domain containing	PDLIM7 PCLO APBA1 ARHGEF11	3.85e-03	152	76	4	1220
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOA3 KMT2D	4.91e-03	25	76	2	775
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	ROR1 HIPK2 PUM2 E2F5 ARID1A MFSD14B GLI3	1.70e-06	199	127	7	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CELF6 CTC1 DTX1 FRS3 ZSCAN25 TNXB	5.99e-06	157	127	6	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCOA3 DTX1 E2F5 DUS2 SSPN SEL1L3	1.43e-05	183	127	6	82fe14fc7039415de41bdfd615a1380bed99f560
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NCOA3 DTX1 E2F5 DUS2 SSPN SEL1L3	1.99e-05	194	127	6	2b5eee7c3e52b63cce94205d18133c7704329c02
ToppCell	NS-critical-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RNF152 TP53I3 RHOV SCNN1A TNS4 CDH3	2.17e-05	197	127	6	a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RNF152 CRACR2A LINC01387 RHOV SCNN1A TNS4	2.24e-05	198	127	6	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MIA3 RNF152 CRACR2A ADARB2 SEL1L3 SCNN1A	2.37e-05	200	127	6	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CRACR2A PCLO ADARB2 MRTFB SCNN1A PLEKHA7	2.37e-05	200	127	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM229A SREBF1 GSN MFSD14B ZNF488 RAB5A	2.37e-05	200	127	6	f0c338877e39226a90c4effe12f6501d33542a73
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MIA3 RNF152 CRACR2A ADARB2 SCNN1A PLEKHA7	2.37e-05	200	127	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
Drug	Cyclosporin A [59865-13-3]; Up 200; 3.4uM; MCF7; HT_HG-U133A	MIA3 TUT4 KMT2B MARS1 SREBF1 CD55 SLC38A10 ATXN7L3B	6.03e-06	175	126	8	3267_UP
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	NCOA2 SCAF8 PUM2 E2F5 ARID1A CREBBP MRTFB SPEN	8.04e-06	182	126	8	3887_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	NCOA2 PPRC1 SCAF8 PUM2 TSC22D2 ARID1A CREBBP MRTFB	8.71e-06	184	126	8	2321_DN
Disease	neurodegenerative disease (implicated_via_orthology)	NRDC MAPT OGDH YBX2 LATS1 SCNN1A	3.36e-05	145	123	6	DOID:1289 (implicated_via_orthology)
Disease	Diffuse Large B-Cell Lymphoma	CREBBP KMT2D SPEN CCDC86	8.32e-05	55	123	4	C0079744
Disease	pre-eclampsia (is_marker_for)	ROBO4 ARID1A CREBBP GSN	1.02e-04	58	123	4	DOID:10591 (is_marker_for)
Disease	Malignant neoplasm of breast	TRERF1 NCOA2 NCOA3 NCOA6 XIRP1 PDLIM7 ROR1 TP53I3 ARID1A TESK1 GSN KMT2D SPEN DOP1A	1.59e-04	1074	123	14	C0006142
Disease	Sezary Syndrome	ARID1A CREBBP KMT2D	1.92e-04	27	123	3	C0036920
Disease	Paratuberculosis	GSN AOC3	2.56e-04	6	123	2	C0030524
Disease	colorectal adenocarcinoma (is_implicated_in)	KMT2B TPRX1 CCDC17	4.20e-04	35	123	3	DOID:0050861 (is_implicated_in)
Disease	cortical surface area measurement	NCOA2 MAPT ROR1 SREBF1 HIPK2 TSC22D2 KIAA1614 GATAD2B MAPRE3 ASCL1 GLI3 MDC1 KIAA1755 PLEKHA7 TNXB	4.88e-04	1345	123	15	EFO_0010736
Disease	prostate cancer (is_marker_for)	NCOA2 NCOA3 KMT2B E2F5 KMT2D	5.07e-04	156	123	5	DOID:10283 (is_marker_for)
Disease	thioredoxin domain-containing protein 12 measurement	DOCK3 TUT4 BSN	5.79e-04	39	123	3	EFO_0008298
Disease	Coffin-Siris syndrome (implicated_via_orthology)	ARID1A SMARCC2	6.09e-04	9	123	2	DOID:1925 (implicated_via_orthology)
Disease	sexual dimorphism measurement	DOCK3 NCOA6 IGF2-AS KMT2B SYN3 MARS1 ACY3 FRS3 PGBD1 POMC ARID1A MAPKBP1 BSN	7.31e-04	1106	123	13	EFO_0021796
Disease	nasopharynx carcinoma (is_marker_for)	DAB2IP ARID1A SPEN	7.72e-04	43	123	3	DOID:9261 (is_marker_for)
Disease	systolic blood pressure change measurement	OGDH SEL1L3 PLEKHA7	1.00e-03	47	123	3	EFO_0006944
Disease	breast cancer (is_marker_for)	TUT4 KMT2B MAPT CD55 KMT2D	1.09e-03	185	123	5	DOID:1612 (is_marker_for)
Disease	factor VIII measurement, coronary artery disease	DAB2IP JCAD MIA3 PRDM8	1.30e-03	113	123	4	EFO_0001645, EFO_0004630
Disease	Coffin-Siris syndrome	ARID1A SMARCC2	1.30e-03	13	123	2	C0265338
Disease	non-alcoholic fatty liver disease, cirrhosis of liver	JCAD CRACR2A SEL1L3	1.42e-03	53	123	3	EFO_0001422, EFO_0003095
Disease	von Willebrand factor measurement, coronary artery disease	DAB2IP JCAD MIA3 PRDM8	1.53e-03	118	123	4	EFO_0001645, EFO_0004629
Disease	Lymphoma, Follicular, Grade 2	CREBBP KMT2D	1.75e-03	15	123	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	CREBBP KMT2D	1.75e-03	15	123	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	CREBBP KMT2D	1.75e-03	15	123	2	C1956130
Disease	Lymphoma, Large-Cell, Follicular	CREBBP KMT2D	1.75e-03	15	123	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	CREBBP KMT2D	1.75e-03	15	123	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	CREBBP KMT2D	1.75e-03	15	123	2	C0079758
Disease	puberty onset measurement	DOCK3 NCOA6 FRS3 ADARB2	1.89e-03	125	123	4	EFO_0005677
Disease	T-Cell Lymphoma	ARID1A KMT2D	1.99e-03	16	123	2	C0079772
Disease	Dyskeratosis Congenita	CTC1 NAF1	1.99e-03	16	123	2	C0265965
Disease	plasma beta-amyloid 1-40 measurement	EP400P1 E2F5	2.25e-03	17	123	2	EFO_0005659
Disease	cortical thickness	NCOA2 KMT2B MAPT ROR1 SREBF1 TSC22D2 KIAA1614 GATAD2B MAPRE3 GLI3 KIAA1755 PLEKHA7	2.41e-03	1113	123	12	EFO_0004840
Disease	breast carcinoma (is_marker_for)	NCOA3 KMT2D MDC1	2.67e-03	66	123	3	DOID:3459 (is_marker_for)
Disease	Bladder Neoplasm	ARID1A CREBBP KMT2D USP7	2.85e-03	140	123	4	C0005695
Disease	Malignant neoplasm of urinary bladder	ARID1A CREBBP KMT2D USP7	2.92e-03	141	123	4	C0005684
Disease	stomach cancer (is_marker_for)	DAB2IP NCOA2 ARID1A KMT2D	3.00e-03	142	123	4	DOID:10534 (is_marker_for)
Disease	Lymphoma, Follicular	CREBBP KMT2D	3.12e-03	20	123	2	C0024301
Disease	cognitive function measurement, self reported educational attainment	TCF20 PDLIM7 DPP8 GATAD2B BSN TNXB	3.80e-03	355	123	6	EFO_0004784, EFO_0008354
Disease	autism spectrum disorder (implicated_via_orthology)	TCF20 SYN3 CREBBP SYN1	3.82e-03	152	123	4	DOID:0060041 (implicated_via_orthology)
Disease	nicotine dependence symptom count, depressive symptom measurement	PCLO MRTFB LATS1	3.84e-03	75	123	3	EFO_0007006, EFO_0009262
Disease	major depressive disorder	NRDC PCLO PGBD1 BSN	4.10e-03	155	123	4	MONDO_0002009
Disease	Weight decreased	MAPT POMC	4.12e-03	23	123	2	C1262477

Protein segments in the cluster

Peptide	Gene	Start	Entry
QQAQALRAVPGPQSP	UPK3BL1	186	B0FP48
PRGQQVTQDGPLQTP	nan	166	A8MWP4
GVPQEPQGLPDQQAS	CCDC17	66	Q96LX7
QLQDRDFQPLQPGAP	ACY3	246	Q96HD9
PQGQPEPGAASPQRQ	CCDC86	81	Q9H6F5
AQEAGPNGNPLPREQ	CTC1	96	Q2NKJ3
PGNGPDQQLQRSPPE	ATXN7L3B	81	Q96GX2
REDIQVPPGNGNIGN	ACBD5	351	Q5T8D3
PQPQLQGGNDDPRRP	ARHGEF11	1396	O15085
QAGVPRPGVPPQQQA	CREBBP	2146	Q92793
EPAQPLSPNQGRVAV	DOP1A	836	Q5JWR5
AFPQEQQKAPPVVGG	GLCE	76	O94923
SDQGVQGQIPEAPPL	CRACR2A	501	Q9BSW2
VLQRSVAAPGNQPQP	BATF3	11	Q9NR55
QAPDPGNGSIQRPYQ	BBS10	456	Q8TAM1
QPSALPQQQREGPEG	CELF6	381	Q96J87
GRQPQPNVSELVVGP	AOC3	131	Q16853
QRQGQYDPPPGASNI	TP53I3	46	Q53FA7
LPKNEPQNPGANSAR	RAB5A	181	P20339
ENRNVGNLAARPPPS	ADARB2	71	Q9NS39
NGLFRPIGTQPPQQQ	PUM2	496	Q8TB72
PAGPAQAKQGTPRAQ	MRNIP	256	Q6NTE8
NAGPRPALNNNLTEP	ARID1A	106	O14497
GQPTVPRQNSAGPQR	DAB2IP	901	Q5VWQ8
ERQEPGSNHPGQPRQ	PCDHA11	786	Q9Y5I1
ADPAERQGPQQQGLP	CT55	16	Q8WUE5
EDLPSPGARGQQEQP	GLI3	441	P10071
VTQAPGAQPLQIQPG	HIPK2	686	Q9H2X6
QGGPPVAQVEQDLPI	MDC1	626	Q14676
AVLQAQPGPPVAAAN	MAGEL2	691	Q9UJ55
NPPNQGQRGISSVPV	LATS1	311	O95835
FQNPQHGEPGLQRVP	MST1L	546	Q2TV78
QGPLGNPENMVQLRP	KIAA1755	401	Q5JYT7
PGIRRAGQNQPAEPD	JCAD	1101	Q9P266
GQNRTVGPNPEPVLS	KIAA1614	351	Q5VZ46
PQAQPQLQGRQAAPG	BSN	3741	Q9UPA5
APQQGRAPQAQPAPG	BSN	3851	Q9UPA5
PAPPQIDNGIIQGER	CD55	226	P08174
VQQPGPGKIPAQQAG	PCLO	441	Q9Y6V0
RGQQQRPLEAQPSAP	MRTFB	596	Q9ULH7
FPGNGDEQPLTENPR	POMC	61	P01189
PQLVQPDGPGVQNTD	LMLN2	171	A0A1B0GTW7
TQPSPGPGQALQNVR	EP400P1	126	Q6ZTU2
EAEAVQQPRGQGTPP	KMT2B	2071	Q9UMN6
IAPNPAQLQGQRGPP	GATAD2B	266	Q8WXI9
DSAPQQNGQPLRPLV	PDLIM7	126	Q9NR12
PVNGLGFPPQNVARV	DTX1	11	Q86Y01
ARTPGQNNLNRPGPQ	DTX1	286	Q86Y01
AFGLPRPQQPQQEEV	NRBP1	406	Q9UHY1
PPRPNLNRGFDQQGL	NCOA6	1261	Q14686
FQRVIPEDGPAAQNP	OGDH	881	Q02218
KRGQPQAPQQTGAFP	ERVK-5	611	Q9HDB9
GAQQERAQPPAASPQ	IGF2-AS	11	Q6U949
QQAPAGQGQGQRPPP	E2F5	11	Q15329
PAAILENGQPPNFQR	DOCK3	1796	Q8IZD9
QQAPQLRPAADGQPS	ASCL1	61	P50553
PDQRDPQVFLQPGQV	FRS3	226	O43559
DGGPQGFTQQPLRPN	DPP8	191	Q6V1X1
LAIPPRIQPSQQDGG	LINC01387	61	J3KSC0
PDSPGLQAPAGQQRA	APBA1	311	Q02410
QGQDVAPPPNPGDQI	MAPRE3	131	Q9UPY8
PAQVPQASGEQPRGN	MAPKBP1	1126	O60336
QASGEQPRGNGANPP	MAPKBP1	1131	O60336
NLGNPPQSAVGVPEN	HUS1B	206	Q8NHY5
QGTLQPEPPQDARFG	ITGA10	536	O75578
QAGAPQGRVPEARPN	GSN	36	P06396
PDQDPGGPRAQELAQ	DUS2	456	Q9NX74
IPNNSGLVGVQPPNV	SCAF8	876	Q9UPN6
REEQGLGPEPAAPQQ	SCNN1A	26	P37088
RAPGGRPAPSQDLNQ	SLC38A10	786	Q9HBR0
EPQNPPANAAPGSQR	PPRC1	441	Q5VV67
VPENGKGPFPQRLNQ	CDH3	116	P22223
NSNNVPLQGAVIPGP	MFSD14B	416	Q5SR56
DDGPQQGPPQQGGQQ	PRH1;	66	P02810
PPQTAAQDPQGQGRV	NUTM2F	551	A1L443
PPQTAAQDPQGQGRV	NUTM2G	536	Q5VZR2
QPNNVIRQPLGPDGS	SZRD1	131	Q7Z422
LQQRPPPQGQQHLSG	SYN1	481	P17600
QAAPPTQGQGRQSRP	SYN1	521	P17600
GQAQLGPQLGQPQPR	SYN3	421	O14994
QQAQALRAVPGPQSP	UPK3BL2	186	E5RIL1
QPEVPAQQAQTGLGP	THAP8	161	Q8NA92
AGLGWPRQQQQQPPP	SEL1L3	6	Q68CR1
PAEQQPLQGGAPQEA	RNF152	136	Q8N8N0
PQPSRANGNINLGPS	SGK2	11	Q9HBY8
QQQQQRRGALPVPPG	TMEM229A	196	B2RXF0
QPGPAVGAPAAQQPQ	TSC22D2	341	O75157
NTQNPPRRGPLSQNG	MIA3	1651	Q5JRA6
GERDFLQLPGPQPQA	LILRA1	261	O75019
PSLPNQQGIGSREPE	RESF1	926	Q9HCM1
DQQQQQQEAPLGPGP	PRDM8	211	Q9NQV8
REQNGYRPNPNPVGQ	NCOA3	371	Q9Y6Q9
DLPTGPRGQQAQPQR	PLEKHA7	376	Q6IQ23
QPRGQQRQGGPPAAD	SSPN	6	Q14714
AQQQVPARPGAPSVQ	SEC23IP	241	Q9Y6Y8
EPPQRPQGNPQEVSG	PGBD1	171	Q96JS3
QRPGANPNPGQSVSV	SNPH	386	O15079
GPQQQQPAGAPQPGA	SMARCC2	1021	Q8TAQ2
PGPGQTQRQETLPNA	EXTL1	256	Q92935
VHPQDQLFQGPGPAR	ROBO4	36	Q8WZ75
QPLQAAPEPGAQGQR	SLC39A5	341	Q6ZMH5
RQQQPPAPAPAAQGT	SREBF1	986	P36956
SAAGPRAGAQQPLPQ	CHSY3	51	Q70JA7
RQEQSPPPARQDLQG	CHSY3	71	Q70JA7
QINGNPVPDENGHIP	C12orf29	126	Q8N999
NNPRPGQLGRLLPNQ	NCOA2	871	Q15596
QIAGFIGPPIPQNQR	ROR1	801	Q01973
RGPRPPNQQQPIEGT	YBX2	236	Q9Y2T7
QRRRQQAPGPQQAPG	YBX2	326	Q9Y2T7
TGQPGAPQLTQNIPR	ZNF488	126	Q96MN9
LQQQPQRVPGQRGRG	TPRX1	26	Q8N7U7
QLDQGGREGPVPQPQ	RHOV	156	Q96L33
QTGVEQPRLPAGPAN	SPEN	3396	Q96T58
NGVPEENLPPIRNGN	RPAP3	46	Q9H6T3
GPPGRLQQAPQVEAK	TNS4	61	Q8IZW8
LQAGPGLPAVNPRDQ	ZSCAN25	201	Q6NSZ9
PPQPQLQQQGRFLAG	TRIL	451	Q7L0X0
GQPQVVPVEGPQRSA	TNXB	1101	P22105
AQQPQAQGPPAQGSE	HGS	756	O14964
SQIPNNGLPRPNFGH	NRDC	401	O43847
LRPDQPQQELTGPGS	SLC4A5	61	Q9BY07
PPGQKGQANATRIPA	MAPT	476	P10636
PQAGQELRVWPPGAQ	NAPRT	446	Q6XQN6
GPVLNNNPPAVVVNS	TESK1	511	Q15569
AQGAQNEPPRLNASP	TCF20	561	Q9UGU0
AQNQNQVRSPGAPGP	ZYX	336	Q15942
RGPHPSQGPIPFQQQ	WDR33	891	Q9C0J8
QQGAQGRIPPLNPGQ	WDR33	936	Q9C0J8
LGPPQQGAQPPHQVQ	TUT4	1456	Q5TAX3
DDPPRITQNPVINGN	USP7	31	Q93009
FDPPGGVQLSQREPQ	XIRP1	1151	Q702N8
RPQQNPVLPVAGERN	MARS1	251	P56192
NRIQIPNDSRPENPG	WDR81	1566	Q562E7
IGQPTQGSPQPVGQQ	YTHDF2	296	Q9Y5A9
LQQQPQRVPGQRGRG	TPRX2	81	P0DV77
QPDANGAPRPNRQEA	ZNF518B	26	Q9C0D4
AQVPVQGGQPLQAPQ	TRERF1	241	Q96PN7
PGVQTNQALGPKPQG	KMT2D	3761	O14686
PAGEQPLQPVLNAVA	NAF1	61	Q96HR8
LPPEIQARVQGQRPG	MZF1	96	P28698