Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondeath receptor binding

BDNF MADD BID NSMAF

4.30e-05251594GO:0005123
GeneOntologyMolecularFunctionrecombination hotspot binding

PRDM7 PRDM9

6.30e-0521592GO:0010844
GeneOntologyBiologicalProcesssynapse organization

IL10RA SDK2 MYCBP2 PPFIA4 PCDHB5 SPTBN2 ZMYND8 PCDHB10 CPEB3 PCDHB6 PCDHB4 SPG11 LRRTM1 CSMD2 BDNF SPTBN4 NEUROD2 CTNNA2 SEMA4A

1.32e-0668515819GO:0050808
GeneOntologyBiologicalProcesssynapse assembly

SDK2 MYCBP2 PCDHB5 SPTBN2 PCDHB10 CPEB3 PCDHB6 PCDHB4 LRRTM1 CSMD2 BDNF SEMA4A

4.69e-0630815812GO:0007416
GeneOntologyBiologicalProcesscell junction organization

IL10RA SDK2 TRIP6 MYCBP2 PPFIA4 PKP4 PCDHB5 SPTBN2 ZMYND8 PCDHB10 CPEB3 PCDHB6 PCDHB4 SPG11 LRRTM1 CSMD2 BDNF SPTBN4 HEG1 NEUROD2 CTNNA2 SEMA4A

5.33e-0697415822GO:0034330
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

SDK2 PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1 PLXNB3

1.43e-051871589GO:0007156
GeneOntologyBiologicalProcesssupramolecular fiber organization

EPS8 HSPG2 FLNC EPPK1 CARMIL2 SPTBN2 WIPF3 GOLGA8K COL5A3 PLEKHG2 ARHGAP35 BID SPTBN4 SHROOM4 FBXO5 CST5 PRKD1 CTNNA2 BAIAP2L2 FOXC2

4.47e-0595715820GO:0097435
GeneOntologyBiologicalProcesspositive regulation of epithelial cell proliferation

JCAD PRKD2 HSPG2 FLT4 EPPK1 MED1 HPN PRKD1 IRS2 PLXNB3

4.57e-0527015810GO:0050679
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PCDHB5 PCDHB10 PCDHB6 PCDHB4 DCHS1

5.28e-05531585GO:0016339
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

JCAD PRKD2 HSPG2 FLT4 EPPK1 CARMIL2 MZB1 BCL2L1 MED1 ITGAL TERT BIRC6 NCOR1 FBXO5 PTPRZ1 HPN BRD9 CST5 PRKD1 IRS2 IL23R PLXNB3

1.11e-04119015822GO:0008284
GeneOntologyBiologicalProcesscell junction assembly

SDK2 TRIP6 MYCBP2 PKP4 PCDHB5 SPTBN2 PCDHB10 CPEB3 PCDHB6 PCDHB4 LRRTM1 CSMD2 BDNF SEMA4A

1.27e-0456915814GO:0034329
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

SDK2 PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 ITGAL DCHS1 PLXNB3

1.55e-0431315810GO:0098742
GeneOntologyBiologicalProcessmeiotic gene conversion

RNF212 PRDM9

1.74e-0431582GO:0006311
GeneOntologyBiologicalProcesspositive regulation of meiotic cell cycle

PRDM7 PRDM9 FBXO5 CDC25C

1.80e-04371584GO:0051446
GeneOntologyBiologicalProcessmeiosis I cell cycle process

RNF212 PRDM7 PRDM9 FBXO5 SHOC1 CDC25C STAG3

1.95e-041551587GO:0061982
GeneOntologyCellularComponentanchoring junction

JCAD HSPG2 FLNC EPPK1 CARMIL2 TRIP6 PKP4 PCDHB5 SPTBN2 ITGAL PRAG1 MPRIP SPTBN4 SHROOM4 HEG1 UBN1 HPN DSTYK SKAP1 MDC1 PRKD1 CTNNA2 BAIAP2L2

1.11e-0697615723GO:0070161
GeneOntologyCellularComponentcell-cell junction

JCAD EPPK1 CARMIL2 PKP4 PCDHB5 SPTBN2 ITGAL SPTBN4 SHROOM4 HEG1 UBN1 HPN SKAP1 PRKD1 CTNNA2 BAIAP2L2

1.01e-0559115716GO:0005911
HumanPhenoSpermatocyte maturation arrest

RNF212 SHOC1 STAG3

9.89e-065523HP:0031039
MousePhenoincreased chromosomal stability

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN5C

1.23e-0761354MP:0010095
DomainPH

PRKD2 SPTBN2 DGKD PLEKHG2 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1

3.86e-0622915711PF00169
DomainPH_DOMAIN

PRKD2 EPS8 SPTBN2 DGKD PLEKHG2 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1

4.34e-0627915712PS50003
DomainPH_domain

PRKD2 EPS8 SPTBN2 DGKD PLEKHG2 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1

4.50e-0628015712IPR001849
DomainPH_dom-like

PRKD2 EPS8 SPTBN2 DGKD PLEKHG2 RGS12 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1 NSMAF

1.50e-0542615714IPR011993
DomainCadherin_2

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

1.76e-05651576PF08266
DomainCadherin_N

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

1.76e-05651576IPR013164
DomainPH

PRKD2 SPTBN2 DGKD PLEKHG2 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1

2.39e-0527815711SM00233
DomainCadherin_C

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4

2.61e-05421575IPR032455
DomainCadherin_C_2

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4

2.61e-05421575PF16492
Domain-

PRKD2 EPS8 SPTBN2 DGKD PLEKHG2 RGS12 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1

2.72e-05391157132.30.29.30
DomainCadherin_CS

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

3.77e-051091577IPR020894
DomainCADHERIN_1

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

4.75e-051131577PS00232
DomainCadherin

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

4.75e-051131577PF00028
DomainCADHERIN_2

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

5.03e-051141577PS50268
Domain-

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

5.03e-0511415772.60.40.60
DomainCA

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

5.32e-051151577SM00112
DomainCadherin-like

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

5.62e-051161577IPR015919
DomainCadherin

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2 DCHS1

6.27e-051181577IPR002126
DomainSCAN_BOX

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN20 ZSCAN5C

1.26e-04581575PS50804
DomainSCAN

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN20 ZSCAN5C

1.26e-04581575PF02023
DomainSCAN_dom

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN20 ZSCAN5C

1.26e-04581575IPR003309
DomainRetrov_capsid_C

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN20 ZSCAN5C

1.37e-04591575IPR008916
DomainProtein_Kinase_C_mu-related

PRKD2 PRKD1

2.09e-0431572IPR015727
DomainSpectrin_bsu

SPTBN2 SPTBN4

4.17e-0441572IPR016343
DomainACTININ_2

FLNC SPTBN2 SPTBN4

9.12e-04231573PS00020
DomainACTININ_1

FLNC SPTBN2 SPTBN4

9.12e-04231573PS00019
DomainActinin_actin-bd_CS

FLNC SPTBN2 SPTBN4

9.12e-04231573IPR001589
DomainSCAN

ZSCAN5A ZSCAN5B ZSCAN20 ZSCAN5C

1.26e-03561574SM00431
PathwayREACTOME_RND2_GTPASE_CYCLE

LEMD3 PKP4 ARHGAP35 PRAG1 GOLGA3

1.84e-05431085M41827
PathwayREACTOME_RND2_GTPASE_CYCLE

PKP4 ANKRD62 ARHGAP35 PRAG1 GOLGA3

2.06e-05441085MM15678
PathwayREACTOME_LOSS_OF_FUNCTION_OF_MECP2_IN_RETT_SYNDROME

BDNF NCOR1 TBL1X

1.18e-04131083M29766
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PITPNM2 PRKD2 HSPG2 FLNC EPPK1 UBE4B MYCBP2 KDM3B KTI12 TNRC6C ARHGAP35 PRAG1 BIRC6 C2CD2 MADD MPRIP PPP1R26 NCOR1 EPS15L1 HEG1 WIZ UBN1 XPO6 BTBD7 USP40 EHMT1 IRS2 WNK2

2.83e-1311051622835748872
Pubmed

Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN5C

4.54e-104162431155506
Pubmed

ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN5C

4.54e-104162427732952
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD SLC4A7 CARMIL2 TRIP6 MYCBP2 EXPH5 CEP162 KDM3B PLEKHG2 PRAG1 RGS12 TAB3 MADD MPRIP USP31 PJA2 DSTYK IRS2 CDC25C SNX2

4.15e-098611622036931259
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

EPS8 VPS13C PKP4 MYO18A DGKD CAVIN3 URB2 BIRC6 C2CD2 RGS12 MADD USP31 EPS15L1 XPO6 ATP11A PLD1 SNX2

5.07e-087191621735337019
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ATP8B4 EXPH5 PPFIA4 SPTBN2 ANKRD62 DGKD ARHGAP35 USP37 BIRC6 PPP1R26 SHROOM4 MYO15B DSTYK ATP11A

8.99e-084931621415368895
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

2.77e-0757162632633719
Pubmed

Protocadherins.

PCDHB5 PCDHB10 PCDHB6 PCDHB4

3.14e-0713162412231349
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

8.02e-0768162611230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

1.13e-0672162610380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

1.33e-0674162610817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

1.68e-0677162610835267
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TRIP6 MYCBP2 SPTBN2 KDM3B ARHGAP35 MED1 TAB3 MPRIP NCOR1 EPS15L1 WIZ MDC1 SNX2

2.00e-065491621338280479
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB5 PCDHB10 PCDHB6 PCDHB4

2.07e-0620162411322959
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

2.10e-0680162610716726
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

JCAD EPS8 TRIP6 CEP162 VPS13C PKP4 SPTBN2 PLEKHG2 TNRC6C RGS12 TAB3 PJA2 NCOR1 EPS15L1 CPLANE1 SNX2

2.67e-068531621628718761
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MYCBP2 PKP4 SPTBN2 GOLGA8K LRRTM1 MPRIP SPTBN4 NCOR1 EPS15L1 WIZ DCHS1 EHMT1 PRKD1 CTNNA2 GOLGA3 WNK2 TBL1X

2.89e-069631621728671696
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 EPS8 FLNC CARMIL2 PPFIA4 PKP4 SPTBN2 MYO18A LRRTM1 ARHGAP35 MADD MPRIP SPTBN4 USP31 EPS15L1 PTPRZ1 CRACDL CTNNA2 GOLGA3 SNX2 WNK2

3.44e-0614311622137142655
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZMYND8 CPEB3 MPRIP NCOR1 XPO6 ASTN1

3.44e-0687162612465718
Pubmed

Functional proteomics mapping of a human signaling pathway.

PRKD2 HSPG2 FLNC FLT4 RMND5A MYCBP2 LEMD3 EXPH5 ZMYND8 KDM3B E4F1 PPP1R26 NCOR1

4.46e-065911621315231748
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

EPS8 LEMD3 ZSCAN5A WIPF3 ARHGAP35 MADD PPP1R26 NCOR1 EPS15L1 UBN1 BRD9 AK1 KIF22 FOXC2

4.70e-066891621436543142
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PITPNM2 UBE4B MYCBP2 VPS13C PAM16 TNRC6C ARHGAP35 C2CD2 SPTBN4 EPS15L1 HPN NAXD USP40 EHMT1 ATP11A PRKD1 CSMD1 SNX2 WNK2 NSMAF TBL1X

6.33e-0614891622128611215
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

7.74e-0658162530377227
Pubmed

Analysis of BCL6-interacting proteins by tandem mass spectrometry.

ZMYND8 ARHGAP35 NCOR1 EHMT1 CSMD1

1.08e-0562162516147992
Pubmed

NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN5C

1.47e-0532162438060382
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

EPS8 SLC4A7 CARMIL2 LEMD3 EXPH5 PKP4 SPTBN2 PAM16 RGS12 PIEZO2 CRACDL ATP11A

1.60e-055691621230639242
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UBE4B MYCBP2 ZMYND8 MYO18A KDM3B ARHGAP35 MED1 NCOR1 EPS15L1 UBN1 XPO6 MDC1 IRS2 SNX2

1.73e-057741621415302935
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SLC4A7 LEMD3 CEP162 VPS13C KDM3B AGPS BIRC6 NCOR1 EPS15L1 GTPBP2 WIZ EHMT1 PLD1 GOLGA3

1.81e-057771621435844135
Pubmed

Both the establishment and maintenance of neuronal polarity require the activity of protein kinase D in the Golgi apparatus.

PRKD2 PRKD1

2.16e-052162218753385
Pubmed

Mapping the interaction of pro-apoptotic tBID with pro-survival BCL-XL.

BCL2L1 BID

2.16e-052162219670908
Pubmed

Inhibition of KIF22 suppresses cancer cell proliferation by delaying mitotic exit through upregulating CDC25C expression.

CDC25C KIF22

2.16e-052162224626146
Pubmed

Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity.

PRKD2 PRKD1

2.16e-052162225639845
Pubmed

Differential expression of PKD1 and PKD2 in gastric cancer and analysis of PKD1 and PKD2 function in the model system.

PRKD2 PRKD1

2.16e-052162222217708
Pubmed

Sequencing of a 'mouse azoospermia' gene panel in azoospermic men: identification of RNF212 and STAG3 mutations as novel genetic causes of meiotic arrest.

RNF212 STAG3

2.16e-052162231125047
Pubmed

Sporadic in utero generalized edema caused by mutations in the lymphangiogenic genes VEGFR3 and FOXC2.

FLT4 FOXC2

2.16e-052162219394045
Pubmed

Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.

CSMD2 CSMD1

2.16e-052162224408017
Pubmed

Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases.

PRKD2 PRKD1

2.16e-052162224336522
Pubmed

FOXC2 and FLT4 Gene Variants in Lymphatic Filariasis.

FLT4 FOXC2

2.16e-052162226091406
Pubmed

Membrane promotes tBID interaction with BCL(XL).

BCL2L1 BID

2.16e-052162219820711
Pubmed

A role for phospholipase D in angiotensin II-induced protein kinase D activation in adrenal glomerulosa cell models.

PRKD1 PLD1

2.16e-052162223178798
Pubmed

The role of PKD in cell polarity, biosynthetic pathways, and organelle/F-actin distribution.

PRKD2 PRKD1

2.16e-052162224492625
Pubmed

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells.

PRKD2 PRKD1

2.16e-052162220819079
Pubmed

Association of a Single Nucleotide Variant in TERT with Airway Disease in Japanese Rheumatoid Arthritis Patients.

TERT ATP11A

2.16e-052162238003027
Pubmed

Suppression of mitochondrial function by oxidatively truncated phospholipids is reversible, aided by bid, and suppressed by Bcl-XL.

BCL2L1 BID

2.16e-052162219654426
Pubmed

Genomic analysis of recurrences and high-grade forms of polymorphous adenocarcinoma.

PRKD2 PRKD1

2.16e-052162230843621
Pubmed

A genetic association study of CSMD1 and CSMD2 with cognitive function.

CSMD2 CSMD1

2.16e-052162227890662
Pubmed

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

BCL2L1 BID

2.16e-052162215353804
Pubmed

KIF22 promotes multiple myeloma progression by regulating the CDC25C/CDK1/cyclinB1 pathway.

CDC25C KIF22

2.16e-052162238713252
Pubmed

The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.

CSMD2 CSMD1

2.16e-052162221439553
Pubmed

SPIG1 negatively regulates BDNF maturation.

FSTL4 BDNF

2.16e-052162224573299
Pubmed

Development of nano affinity columns for the study of ligand (including SARS-CoV-2 related proteins) binding to heparan sulfate proteoglycans.

HSPG2 TERT

2.16e-052162234132262
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

EPPK1 ZMYND8 URB2 MPRIP UBN1 DSTYK SHOC1 SEMA4A GOLGA3

2.78e-05332162937433992
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

JCAD TRIP6 MYCBP2 LEMD3 CEP162 PKP4 SPTBN2 BIRC6 TAB3 MADD USP31 NCOR1 WIZ PTPRZ1 CDC25C KIF22

3.43e-0510491621627880917
Pubmed

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.

TERT ATP11A CSMD1

4.33e-0515162323583980
Pubmed

Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".

RNF212 PRDM9 GOLGA3

5.31e-0516162329878059
Pubmed

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.

NCOR1 WIZ EHMT1 TBL1X

5.82e-0545162421258344
Pubmed

Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.

PCDHB5 PCDHB6 PCDHB4

6.43e-0517162318279309
Pubmed

Rare Variants in LAMA5 Gene associated with FLT4 and FOXC2 Mutations in Primary Lymphedema May Contribute to Severity.

FLT4 FOXC2

6.45e-053162229908552
Pubmed

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ.

MED1 NCOR1

6.45e-053162230575522
Pubmed

Identification of two new members of the CSMD gene family.

CSMD2 CSMD1

6.45e-053162212906867
Pubmed

Functional and therapeutic significance of protein kinase D enzymes in invasive breast cancer.

PRKD2 PRKD1

6.45e-053162226253275
Pubmed

Active fragments from pro- and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence.

BCL2L1 BID

6.45e-053162220140092
Pubmed

Effect of blocking VEGF, hTERT and Bcl-xl by multiple shRNA expression vectors on the human laryngeal squamous carcinoma xenograft in nude mice.

BCL2L1 TERT

6.45e-053162218285708
Pubmed

Protein kinase D1/2 is involved in the maturation of multivesicular bodies and secretion of exosomes in T and B lymphocytes.

PRKD2 PRKD1

6.45e-053162226045048
Pubmed

Adenovirus-mediated transfer of tris-shRNAs induced apoptosis of nasopharyngeal carcinoma cell in vitro and in vivo.

BCL2L1 TERT

6.45e-053162221669490
Pubmed

A Novel Conserved Domain Mediates Dimerization of Protein Kinase D (PKD) Isoforms: DIMERIZATION IS ESSENTIAL FOR PKD-DEPENDENT REGULATION OF SECRETION AND INNATE IMMUNITY.

PRKD2 PRKD1

6.45e-053162227662904
Pubmed

Membrane-insertion fragments of Bcl-xL, Bax, and Bid.

BCL2L1 BID

6.45e-053162215323553
Pubmed

Protein kinase D in vascular biology and angiogenesis.

PRKD2 PRKD1

6.45e-053162221488147
Pubmed

PLD1 participates in BDNF-induced signalling in cortical neurons.

BDNF PLD1

6.45e-053162226437780
Pubmed

Protein tyrosine phosphatase receptor type Z is involved in hippocampus-dependent memory formation through dephosphorylation at Y1105 on p190 RhoGAP.

ARHGAP35 PTPRZ1

6.45e-053162216513268
Pubmed

Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion.

ITGAL SKAP1

6.45e-053162217646386
Pubmed

Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart.

PRKD2 PRKD1

6.45e-053162238419169
Pubmed

A/ASP/VAL allele combination of IGF1R, IRS2, and UCP2 genes is associated with better metabolic profile, preserved energy expenditure parameters, and low mortality rate in longevity.

UCP2 IRS2

6.45e-053162221340542
Pubmed

Expression of the protein kinase D (PKD) family during mouse embryogenesis.

PRKD2 PRKD1

6.45e-053162216377259
Pubmed

A(2a) adenosine receptor mediates HepG2 cell apoptosis by downregulating Bcl-X(L) expression and upregulating Bid expression.

BCL2L1 BID

6.45e-053162222213163
Pubmed

Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.

PRKD2 PRKD1

6.45e-053162232747433
Pubmed

Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland.

PRKD2 PRKD1

6.45e-053162226426580
Pubmed

Characterization of the biological effects of a novel protein kinase D inhibitor in endothelial cells.

PRKD2 PRKD1

6.45e-053162220497126
Pubmed

A stapled BID BH3 helix directly binds and activates BAX.

BCL2L1 BID

6.45e-053162217052454
Pubmed

Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members.

BCL2L1 TERT

6.45e-053162229937479
Pubmed

The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity.

PRKD2 PRKD1

6.45e-053162219581308
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

EPS8 SLC4A7 TRIP6 LEMD3 PKP4 ZMYND8 E4F1 URB2 MED1 DNAJC2 MPRIP WIZ CRACDL MDC1 BRD9 EHMT1 CTNNA2 TMCO1 KIF22

7.47e-0514971621931527615
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-ĪŗB signalling activation.

PRKD2 SLC4A7 TRIP6 LEMD3 PKP4 COL5A3 TAB3 PLD1 KIF22

7.55e-05378162934315543
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

FLNC SPTBN2 SPTBN4

7.69e-0518162312119179
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

HSPG2 UBE4B KDM3B CAVIN3 USP37 TAB3 EPS15L1 USP40 AK1 TMCO1

9.28e-054811621028190767
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYCBP2 KDM3B TNRC6C ARHGAP35 BIRC6 XPO6 EHMT1

9.42e-05225162712168954
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

LEMD3 PKP4 ARHGAP35 MPRIP EPS15L1 PTPRZ1 CTNNA2

1.11e-04231162716452087
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

JCAD PRKD2 UBE4B MYCBP2 SPTBN2 ZMYND8 MADD MPRIP SPTBN4 EPS15L1 NEUROD2 WIZ CIAO3 HPS4 ASTN1 GOLGA3 PLXNB3

1.11e-0412851621735914814
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZSCAN5DP TRIP6 ZSCAN5A ZMYND8 KDM3B BCL2L1 TERT NCOR1 ZSCAN5B ZSCAN20 WIZ BTBD7 ZSCAN5C

1.13e-048081621320412781
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

BIRC6 SHROOM4 USP31 HEG1 PLXNB3

1.25e-04103162510574462
Pubmed

SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates.

ITGAL SKAP1

1.29e-044162212652296
Pubmed

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop.

PRKD2 PRKD1

1.29e-044162228428613
Pubmed

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.

BCL2L1 BID

1.29e-04416229727492
Pubmed

NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9.

IRF7 NCOR1

1.29e-044162232644192
Pubmed

Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function.

BCL2L1 IRS2

1.29e-044162210679027
Pubmed

Bidirectional transcription from human LRRTM2/CTNNA1 and LRRTM1/CTNNA2 gene loci leads to expression of N-terminally truncated CTNNA1 and CTNNA2 isoforms.

LRRTM1 CTNNA2

1.29e-044162221708131
Pubmed

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature.

FLT4 FOXC2

1.29e-044162226389677
Pubmed

A recurrent ITGA9 missense mutation in human fetuses with severe chylothorax: possible correlation with poor response to fetal therapy.

FLT4 FOXC2

1.29e-044162218973153
Pubmed

SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.

CAVIN3 EPS15L1

1.29e-044162219262564
Pubmed

Endothelial FOXC1 and FOXC2 promote intestinal regeneration after ischemia-reperfusion injury.

FLT4 FOXC2

1.29e-044162237154714
InteractionYWHAH interactions

JCAD PRKD2 EPPK1 SLC4A7 CARMIL2 TRIP6 MYCBP2 EXPH5 CEP162 KDM3B BCL2L1 PLEKHG2 MED1 PRAG1 RGS12 TAB3 MADD MPRIP USP31 PJA2 PRKD1 IRS2 CDC25C SNX2 WNK2 SMTNL2

6.56e-07110216126int:YWHAH
InteractionTOP3B interactions

PITPNM2 PRKD2 HSPG2 FLNC EPPK1 UBE4B MYCBP2 SPTBN2 KDM3B KTI12 TNRC6C ARHGAP35 PRAG1 BIRC6 C2CD2 MADD MPRIP PPP1R26 NCOR1 EPS15L1 HEG1 WIZ UBN1 XPO6 BTBD7 MDC1 USP40 EHMT1 IRS2 WNK2

1.69e-06147016130int:TOP3B
InteractionYWHAZ interactions

JCAD PRKD2 SLC4A7 CARMIL2 MYCBP2 EXPH5 CEP162 SPTBN2 MYO18A TERT RGS12 TAB3 MADD MPRIP USP31 NCOR1 UCP2 MDC1 OSBPL7 PRKD1 IRS2 PRR14L CDC25C GOLGA3 WNK2 SMTNL2

1.70e-05131916126int:YWHAZ
InteractionRGS12 interactions

PRKD2 MYCBP2 RGS12 WIZ EHMT1

2.89e-05451615int:RGS12
Cytoband5q31

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 KDM3B PCDHA2 CDC25C

8.67e-0911516285q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

MZB1 PCDHGA9 PCDHB5 PCDHB10 FSTL4 PCDHB6 PCDHB4 KDM3B PCDHA2 CDC25C

1.24e-0729816210chr5q31
Cytoband17p11.2

SHMT1 CCDC144CP MPRIP NCOR1 CCDC144A

2.64e-04159162517p11.2
Cytoband19q13.43

ZSCAN5DP ZSCAN5A ZSCAN5B ZSCAN5C

2.65e-0487162419q13.43
CytobandEnsembl 112 genes in cytogenetic band chr17p11

SHMT1 CCDC144CP MPRIP NCOR1 CCDC144A

8.02e-042031625chr17p11
Cytoband13q34

NAXD ATP11A IRS2

9.37e-0454162313q34
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PRKD2 SPTBN2 DGKD PLEKHG2 MPRIP SPTBN4 SKAP1 OSBPL7 PRKD1 IRS2 PLD1

6.18e-0820611211682
GeneFamilyClustered protocadherins

PCDHGA9 PCDHB5 PCDHB10 PCDHB6 PCDHB4 PCDHA2

2.76e-0664112620
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

BCL2L1 PPP1R26 PPP1R3A NCOR1 UBN1 CSMD1 CDC25C

1.34e-041811127694
GeneFamilyEF-hand domain containing|Spectrins

SPTBN2 SPTBN4

7.83e-04711221113
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZSCAN5DP ZSCAN5A E4F1 PRDM7 ZFY ZNF594 ZSCAN5B PRDM9 ZSCAN20 WIZ ZSCAN5C ZBTB18

1.64e-037181121228
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 FLT4 SDK2 FSTL4 PXDNL

3.28e-031611125593
GeneFamilyATPase phospholipid transporting

ATP8B4 ATP11A

3.79e-031511221210
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

DNAJC2 NCOR1 ZSCAN20

4.33e-03531123532
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM7 PRDM9

4.87e-031711221197
GeneFamilyUbiquitin specific peptidases

USP37 USP31 USP40

5.05e-03561123366
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

EPS8 SLC4A7 MYCBP2 PKP4 ZMYND8 KDM3B SPG11 ARHGAP35 MED1 C2CD2 BDNF DNAJC2 PJA2 HEG1 XPO6 ZBTB18 SNX2 NSMAF TBL1X

1.42e-0685616119M4500
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 RGS7BP EXPH5 PPFIA4 HPN ATP11A WNK2 CCDC144A

4.04e-071851628636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 SPTBN2 FSTL4 MADD SPTBN4 CRACDL SKAP1 CSMD1

4.21e-0718616287278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

JCAD EXPH5 BDNF NEUROD2 CRACDL SEMA4A ZBTB18

4.58e-06181162758f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 SDK2 LRRTM1 PTPRZ1 ASTN1 CSMD1 PLXNB3

4.75e-061821627a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 RGS7BP EXPH5 PPFIA4 BDNF NEUROD2 ZBTB18

5.28e-061851627cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells-Tumor_ECs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

JCAD HSPG2 FLT4 CAVIN3 SHROOM4 HEG1 DCHS1

5.67e-061871627be5f8c5802b0fa8cc1e274fdf06b13eb8ceb8ad4
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FLT4 RGS7BP WIPF3 CAVIN3 SHROOM4 FOXC2

5.87e-061881627a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FLT4 RGS7BP WIPF3 CAVIN3 SHROOM4 FOXC2

5.87e-06188162754550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 RGS7BP COL5A3 PLEKHG2 C2CD2 PIEZO2 FOXC2

6.51e-0619116277b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

PRKD2 HSPG2 PKP4 BCL2L1 PRAG1 SHROOM4 CRACDL

6.51e-061911627c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 RGS7BP COL5A3 PLEKHG2 C2CD2 PIEZO2 FOXC2

6.51e-061911627cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

PRKD2 HSPG2 PKP4 BCL2L1 PRAG1 SHROOM4 CRACDL

6.74e-0619216278a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 WIPF3 FSTL4 MADD SPTBN4 CRACDL CSMD1

6.97e-061931627be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 JCAD FLT4 RGS7BP PKP4 SHROOM4 HEG1

6.97e-06193162702f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 JCAD FLT4 RGS7BP PKP4 SHROOM4 HEG1

6.97e-0619316275122b1ffba42de190061be34ecdc6176f84e56a3
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 WIPF3 FSTL4 MADD SPTBN4 CRACDL CSMD1

6.97e-0619316270c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 WIPF3 FSTL4 MADD SPTBN4 CRACDL CSMD1

6.97e-0619316278689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

HSPG2 FLT4 PRAG1 SHROOM4 PIEZO2 NOD1 PRKD1

7.71e-061961627e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 JCAD PRKD2 RGS7BP PKP4 SHROOM4 HEG1

8.79e-06200162772ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 JCAD PRKD2 RGS7BP PKP4 SHROOM4 HEG1

8.79e-0620016275c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellmild_COVID-19_(asymptomatic)-MAIT|World / disease group, cell group and cell class (v2)

FLT4 COL5A3 SPTBN4 BRD9 CSMD1 BAIAP2L2

2.07e-0515316262b4c69f6db17927d6506a645ac058133e60b0103
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MZB1 ZNF831 ITGAL TERT BID SKAP1

2.15e-051541626ee03b386d28a524084eaf1c0091f7389daa34250
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MZB1 ZNF831 ITGAL TERT BID SKAP1

2.15e-0515416263fa6f77ad2c30ec24b9b904e2732ec5b419dff5b
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WIPF3 ZNF831 BDNF NEUROD2 SLC9B2 SEMA4A

2.48e-0515816269e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

WIPF3 PCDHB6 LRRTM1 CSMD2 DIRAS3 CTNNA2

2.66e-051601626636127753e3a22831f39d4c8170df40901e4329d
ToppCellSevere-Lymphoid-NK-Proliferating_T|Severe / Condition, Lineage, Cell class and cell subclass

PITPNM2 WIPF3 MYO18A SHMT1 ZNF831 KIF22

2.66e-051601626cb2276d9bd78508644420e9580d3c17b914224cb
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

WIPF3 PCDHB6 LRRTM1 CSMD2 DIRAS3 CTNNA2

2.66e-051601626cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 SPTBN2 NAB2 ZSCAN20 SLC9B2 STAG3

2.86e-0516216262787be283b7a705647058aeb9bc54006ce5ffe95
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 SLC4A7 PPFIA4 WNT8B PRDM9 SEMA4A

3.17e-0516516262477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 NWD1 CSMD2 CTNNA2 CSMD1 CDC25C

3.39e-0516716263edb0570e583bb527165bcd8a4c25a042054043b
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)|Hippocampus / BrainAtlas - Mouse McCarroll V32

WIPF3 ZNF831 BDNF NEUROD2 CRACDL ZBTB18

3.50e-0516816266db453cbbbaf4144a86fadcfa5805d33396713b5
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PCDHB5 CSMD2 SPTBN4 KCNH6 CRACDL WNK2

3.62e-05169162696a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC ATP8B4 BDNF PPP1R3A PXDNL WNK2

3.74e-0517016263f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 SPTBN2 NAB2 ZSCAN20 SLC9B2 STAG3

3.74e-0517016268d3c51364a332020810836e2055c60893c10d7f3
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 SDK2 GOLGA8K COL5A3 PTPRZ1 PLXNB3

4.13e-051731626789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCellImmune_cells-pro-B|World / Lineage and Cell class

PRKD2 MZB1 CRACDL UCP2 SNX2 SMTNL2

4.26e-051741626e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC COL5A3 CAVIN3 HEG1 RNF146 DCHS1

4.26e-0517416261d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 BDNF NEUROD2 CRACDL SLC9B2 SEMA4A

4.40e-051751626c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

WIPF3 PCDHB6 LRRTM1 CSMD2 DIRAS3 CTNNA2

4.54e-051761626852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

WIPF3 PCDHB6 LRRTM1 CSMD2 DIRAS3 CTNNA2

4.54e-051761626d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CSMD2 PTPRZ1 SLC9B2 CTNNA2 CSMD1 PLXNB3

4.69e-051771626b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 SPTBN2 NAB2 ZSCAN20 SLC9B2 STAG3

4.69e-0517716264a697866ed542d3201714234cee03451adf1dcc9
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

PKP4 DGKD ARHGAP35 MPRIP DCHS1 CCDC144A

4.99e-05179162668511e87b12b8253de7771e5ccfc5869248b8450
ToppCelldroplet-Fat-Bat-18m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 RGS7BP SPG11 BCL2L1 PRKD1 TBL1X

4.99e-051791626e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF831 RGS12 AK1 PRKD1 CDC25C KIF22

4.99e-0517916264166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCelldroplet-Fat-Bat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 RGS7BP SPG11 BCL2L1 PRKD1 TBL1X

4.99e-0517916269863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCelldroplet-Fat-Bat-18m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 RGS7BP SPG11 BCL2L1 PRKD1 TBL1X

4.99e-051791626dfe110add7228cd834b35916cbcc849769a01bb9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 PPFIA4 SPTBN2 ITGAL NEUROD2 ZBTB18

5.15e-0518016266ac62bf1251978c8c12e715f7b73144fca619794
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JCAD HSPG2 FLT4 SHROOM4 PIEZO2 DCHS1

5.47e-051821626997d37ca2af661c92a56add888762724dfccc890
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

JCAD HSPG2 FLT4 SHROOM4 HEG1 DCHS1

5.47e-051821626d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCellImmune_cells-large_pre-B.|World / Lineage and Cell class

CARMIL2 MZB1 FBXO5 UCP2 SNX2 SMTNL2

5.64e-05183162681b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC PCDHB5 CAVIN3 BDNF PXDNL CST5

5.81e-05184162654e5b63f55b8d6eccad53d389ea9c78f991e1414
ToppCellP03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL5A3 LRRTM1 PTPRZ1 SKAP1 WNK2 PLXNB3

5.81e-0518416268880ff36c243cc60a524d74934d000aef26a70ac
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PKP4 CPEB3 SPTBN4 PXDNL SKAP1 PRKD1

5.81e-051841626e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC PCDHB5 CAVIN3 BDNF PXDNL CST5

5.81e-0518416267b5678718719020b52e7c2a7bd9797987defd7ff
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARMIL2 RGS7BP EXPH5 BDNF NEUROD2 ZBTB18

5.81e-0518416267d9bcdaff8cbea4c50ab7db0f8e01f6bbd0ef593
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD FLT4 NWD1 RGS7BP PTPRZ1 DCHS1

5.99e-051851626f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated|PND07-28-samps / Age Group, Lineage, Cell class and subclass

IL10RA MZB1 MROH5 ZNF831 PLXNB3

6.09e-0511416251c99483a492d08b6bb745006fe24c22841dc57ad
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FLT4 PCDHGA9 WIPF3 CAVIN3 FOXC2

6.17e-051861626f23f21781a758541f59c06efa7739d26a03fb478
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FLT4 PCDHGA9 WIPF3 CAVIN3 FOXC2

6.17e-0518616260de87109da9324c597fadf2eb782f0f158afe832
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

JCAD EXPH5 ZMYND8 DGKD BDNF TBL1X

6.36e-0518716267e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHMT1 TERT PTPRZ1 ASTN1 CDC25C KIF22

6.36e-051871626a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHMT1 TERT PTPRZ1 ASTN1 CDC25C KIF22

6.36e-05187162638ee33295a21db4aae5ba085df033db9693e41c6
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 WIPF3 ZNF831 BDNF SPTBN4 CRACDL

6.36e-051871626e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 WIPF3 ZNF831 BDNF SPTBN4 CRACDL

6.36e-05187162624cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHMT1 TERT PTPRZ1 ASTN1 CDC25C KIF22

6.36e-051871626dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

JCAD HSPG2 SHROOM4 HEG1 DCHS1 FOXC2

6.36e-051871626febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 WIPF3 ZNF831 BDNF SPTBN4 CRACDL

6.36e-0518716262f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CPEB3 TAB3 EPS15L1 XPO6 OSBPL7 PLD1

6.55e-0518816263638d85452de15a060146628fbbad9d2a36feb13
ToppCellLPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 JCAD FLT4 RGS7BP USP31 HEG1

6.55e-051881626789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HSPG2 PCDHB5 PCDHB10 COL5A3 PRKD1 FOXC2

6.55e-051881626de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 SLC4A7 PKP4 MADD SPTBN4 ASTN1

6.55e-051881626a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SDK2 CAVIN3 C2CD2 USP31 NOD1 OSBPL7

6.74e-051891626e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EXPH5 PPFIA4 SPTBN2 SPTBN4 NEUROD2 ZBTB18

6.74e-051891626f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

WIPF3 ZNF831 BDNF NEUROD2 CRACDL ZBTB18

6.74e-0518916264b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCellMyeloid-Myeloid-C_(Cd16+_Monocyte)|Myeloid / shred on cell class and cell subclass (v4)

WIPF3 ITGAL BDNF NOD1 CTNNA2

6.89e-051171625d1936e76a935216783a73ab414e4147fa48e68eb
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 RGS7BP WIPF3 CAVIN3 FOXC2

6.94e-051901626e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 RGS7BP WIPF3 CAVIN3 FOXC2

6.94e-051901626f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 RGS7BP WIPF3 CAVIN3 FOXC2

6.94e-051901626b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 FLT4 RGS7BP WIPF3 CAVIN3 FOXC2

6.94e-051901626f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 FLT4 RGS7BP WIPF3 CAVIN3 FOXC2

6.94e-051901626a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

FSTL4 ZNF831 ITGAL SKAP1 CTNNA2 CSMD1

6.94e-051901626e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 PKP4 CPEB3 PXDNL SKAP1 PRKD1

6.94e-0519016263dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 FLT4 RGS7BP WIPF3 CAVIN3 FOXC2

6.94e-05190162657c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCellfacs-Trachea-nan-3m-Lymphocytic|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL FBXO5 SKAP1 CDC25C IL23R KIF22

7.15e-05191162689eb4e30052d0d4a2952157ca743291900ce8de2
ToppCellfacs-Trachea-nan-3m-Lymphocytic-T_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL FBXO5 SKAP1 CDC25C IL23R KIF22

7.15e-0519116260bf575eba311745fb75f9523f7fc81f73848e25d
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

JCAD HSPG2 FLT4 SHROOM4 PIEZO2 DCHS1

7.15e-051911626cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 MZB1 COL5A3 DGKD BCL2L1 SMTNL2

7.15e-051911626318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 WIPF3 CAVIN3 SLC9B2 FOXC2

7.15e-05191162651cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCellfacs-Trachea-nan-3m-Lymphocytic-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAL FBXO5 SKAP1 CDC25C IL23R KIF22

7.15e-051911626c57df363e3a6e61d2bdca1955330f1899b964267
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 WIPF3 CAVIN3 SLC9B2 FOXC2

7.15e-051911626a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC FLT4 WIPF3 CAVIN3 SLC9B2 FOXC2

7.15e-05191162638681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPS8 MZB1 COL5A3 DGKD BCL2L1 SMTNL2

7.15e-0519116264aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLT4 PCDHB5 PIEZO2 HPS4 UCP2 FOXC2

7.35e-051921626b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLT4 PCDHB5 PIEZO2 HPS4 UCP2 FOXC2

7.35e-051921626ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC4A7 PKP4 CPEB3 PXDNL SKAP1 PRKD1

7.35e-051921626562df5e87038c500dd3a003fe5374cb31946b145
ToppCellNS-control-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL10RA CARMIL2 COL5A3 ITGAL SKAP1 IL23R

7.35e-051921626ef252dd9df161f665f53c047c0514381f80d6683
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPS8 RGS7BP SHROOM4 HPN ATP11A PRKD1

7.35e-051921626fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLT4 DIRAS3 USP31 PIEZO2 UCP2 FOXC2

7.35e-051921626d43caf42ec744e895137f31ef65a990e250669d2
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD MYO18A HEG1 PIEZO2 BTBD7 UCP2

7.35e-0519216261ccc47792edf9ee23501c8e2165d11271636b66a
DrugCGP 19835A

PRKD2 CAVIN3 PPP1R3A NOD1 HPS4 PRKD1

1.99e-06541586CID005479141
DrugDiphemanil methylsulfate [62-97-5]; Down 200; 10.2uM; MCF7; HT_HG-U133A

VPS13C PKP4 ARHGAP35 MED1 NOD1 BTBD7 ATP11A IRS2 TBL1X

9.61e-0619615891494_DN
DrugAtractyloside potassium salt [102130-43-8]; Up 200; 5uM; HL60; HT_HG-U133A

SLC4A7 PKP4 ZMYND8 SHMT1 KCNH6 CIAO3 CDC25C TMCO1 ZBTB18

1.13e-0520015892573_UP
DrugAC1LDMDX

PRKD2 CAVIN3 BCL2L1 PRKD1 CDC25C

1.18e-05431585CID000621355
Drugrhodamine 6G

PRKD2 CAVIN3 KCNH6 PRKD1 CTNNA2

1.32e-05441585CID000013806
DrugAC1L4NFY

PRKD2 CAVIN3 ITGAL PRKD1

1.78e-05231584CID000160335
DiseaseSchizophrenia

IL10RA SPTBN2 SHMT1 LRRTM1 CSMD2 RGS12 BDNF BID KCNH6 PTPRZ1 HPS4 UCP2 CTNNA2 CSMD1 CDC25C

5.06e-0588315115C0036341
Diseaserecombination rate

RNF212 PRDM9

7.78e-0531512EFO_0004863
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN2 SPTBN4

1.55e-0441512DOID:0050882 (implicated_via_orthology)
Diseasepallidum volume

BCL2L1 BIRC6 PJA2

2.78e-04251513EFO_0006933
DiseaseCongenital musculoskeletal anomalies

TMCO1 FOXC2

3.85e-0461512C0151491
Diseasecentral nervous system cancer

TERT PIEZO2 GOLGA3

5.32e-04311513EFO_0000326
DiseaseGlobal developmental delay

SPTBN2 KDM3B GTPBP2 CTNNA2 ZBTB18

6.24e-041331515C0557874
Diseaseacute lymphoblastic leukemia (is_marker_for)

KDM3B BCL2L1 TERT

7.00e-04341513DOID:9952 (is_marker_for)
Diseasemalignant epithelial tumor of ovary

TERT SKAP1 ZBTB18

7.62e-04351513MONDO_0018364
DiseaseInflammatory Bowel Diseases

IL10RA ITGAL IL23R

7.62e-04351513C0021390
Diseaseaspartate aminotransferase measurement

PRKD2 SLC4A7 FSTL4 SHMT1 ARHGAP35 PRAG1 BIRC6 BDNF MADD DSTYK CTNNA2 CSMD1 WNK2

7.91e-0490415113EFO_0004736
Diseasecervical cancer (is_marker_for)

BCL2L1 MDC1 CDC25C

8.29e-04361513DOID:4362 (is_marker_for)
Diseaseosteochondrodysplasia (implicated_via_orthology)

PAM16 RNF146

9.15e-0491512DOID:2256 (implicated_via_orthology)
Diseasephosphatidylcholine 32:1 measurement

CEP162 DCHS1 CSMD1

9.72e-04381513EFO_0010373
Diseasesleep apnea

BDNF PPP1R3A SKAP1

1.13e-03401513EFO_0003877
DiseaseUterine leiomyoma, estrogen-receptor negative breast cancer

EXPH5 TERT

1.14e-03101512EFO_1000650, HP_0000131
DiseaseX-21448 measurement

DGKD USP40

1.14e-03101512EFO_0800816
DiseaseLiver carcinoma

CPEB3 BCL2L1 MED1 TERT DIRAS3 BID IRS2 CSMD1 CDC25C

1.25e-035071519C2239176
Diseaseplatelet crit

JCAD SLC4A7 EXPH5 DGKD BCL2L1 TERT C2CD2 BID HPN SKAP1 DCHS1 IRS2 SNX2

1.26e-0395215113EFO_0007985
Diseaselymphocyte count

JCAD NWD1 EPPK1 SLC4A7 RMND5A CARMIL2 UBE4B PCDHGA9 EXPH5 DGKD ZNF831 NCOR1 EPS15L1 XPO6 OSBPL7 GOLGA3 NSMAF

1.38e-03146415117EFO_0004587
Diseasecognitive impairment measurement

FSTL4 PXDNL CSMD1

1.49e-03441513EFO_0007998
Diseasedisorder of pharynx

CARMIL2 ITGAL IL23R

1.70e-03461513MONDO_0020592
Diseaseblood phosphate measurement

PITPNM2 HSPG2 SPTBN2 PRAG1 USP40

2.06e-031741515EFO_0010972
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

MADD PPP1R3A UCP2 IRS2

2.11e-031051514DOID:9352 (implicated_via_orthology)
DiseaseHamman-Rich syndrome

TERT ATP11A

2.27e-03141512C0085786
Diseasetriacylglycerol 46:2 measurement

DNAJC2 CSMD1

2.27e-03141512EFO_0010402
Diseasemean platelet volume

PITPNM2 JCAD ATP8B4 PCDHGA9 ZMYND8 TERT RGS12 MPRIP UBN1 DSTYK UCP2 IRS2 SNX2

2.31e-03102015113EFO_0004584
DiseaseAntihypertensive use measurement

HSPG2 PKP4 ZNF831 MADD PXDNL SEMA4A

2.50e-032651516EFO_0009927
Diseasecoffee consumption measurement

PRKD2 ZMYND8 BIRC6 BDNF CTNNA2

2.50e-031821515EFO_0006781
Diseasenervous system disorder

SHMT1 BDNF NOD1

2.55e-03531513C0027765
DiseaseHuntington's disease (is_marker_for)

BDNF NCOR1 UCP2

2.55e-03531513DOID:12858 (is_marker_for)
DiseaseTetralogy of Fallot

FLT4 FOXC2

2.98e-03161512C0039685
Diseasealcohol use disorder (implicated_via_orthology)

EPS8 KDM3B SHMT1 MADD BRD9

3.37e-031951515DOID:1574 (implicated_via_orthology)
Diseasesugar consumption measurement

FSTL4 CRACDL CSMD1 SNX2

3.42e-031201514EFO_0010158
Diseasetriglycerides to total lipids in large HDL percentage

RGS12 MADD RNF146

3.63e-03601513EFO_0022330
DiseaseHereditary Diffuse Gastric Cancer

BCL2L1 BDNF BID NAXD IRS2 CTNNA2

4.08e-032931516C1708349
DiseaseHydrops Fetalis

FLT4 FOXC2

4.20e-03191512C0020305
Diseasecerebral microbleeds

HSPG2 CTNNA2

4.20e-03191512EFO_0010059
DiseaseUsual Interstitial Pneumonia

TERT ATP11A

4.20e-03191512C4721509
DiseaseHamman-Rich Disease

TERT ATP11A

4.20e-03191512C4721508
DiseaseStomach Neoplasms

BCL2L1 BDNF BID NAXD IRS2 CTNNA2

4.36e-032971516C0038356
Diseasehippocampal volume

EPPK1 MYCBP2 LEMD3 PRAG1 MADD WNK2

4.36e-032971516EFO_0005035
DiseaseMalignant neoplasm of stomach

BCL2L1 BDNF BID NAXD IRS2 CTNNA2

4.58e-033001516C0024623
Diseasebase metabolic rate measurement

BDNF GOLGA3

4.65e-03201512EFO_0007777
DiseaseFamilial Idiopathic Pulmonary Fibrosis

TERT ATP11A

4.65e-03201512C4721952
Diseaseinterstitial lung disease

TERT ATP11A CSMD1

4.95e-03671513EFO_0004244

Protein segments in the cluster

PeptideGeneStartEntry
TSLHESEGSLGNSRS

PKP4

131

Q99569
GADISQGSDRTLLSH

URB2

1136

Q14146
AHGASLTDLANLSEG

EPS15L1

571

Q9UBC2
FALRNLSTGAAHSEG

COX18

186

Q8N8Q8
NSHRSLDGLSRTQGE

BIRC6

586

Q9NR09
AGSRGLTSLADTFEH

BDNF

51

P23560
QSGLGALSRSHDTTS

CAVIN3

61

Q969G5
AQARLLSSLSGSHSG

CSMD1

1686

Q96PZ7
DGHSQHSRLLSSLSG

CSMD2

1676

Q7Z408
DDLLDQITGGDHSRT

BRD9

441

Q9H8M2
HRGASGESLLASGES

CTSL3P

151

Q5NE16
AQALAGHSSSGLREL

CARMIL2

266

Q6F5E8
GHSSSGLRELSLAGN

CARMIL2

271

Q6F5E8
LELEVAERGGQHSSS

C2orf27A

86

P0DPF5
LVSANTGIAGTTREH

GTPBP2

286

Q9BX10
GADIEARSQDGHTSL

ANKRD62

161

A6NC57
NGATGHSSSLDAREV

BCL2L1

66

Q07817
TSDHLSEFAGEGLRT

ATP8B4

581

Q8TF62
TAEVAGSSQTGLHRI

CCDC144CP

1186

Q8IYA2
SAADGRGTAITHALT

DNAJC2

6

Q99543
ALSNALHSLDGATSR

ASTN1

836

O14525
FLDRTGLTAVSHNGS

NWD1

1211

Q149M9
RGSGSESAHKTQRAL

RGS7BP

36

Q6MZT1
ALHIGSVSATDRDSG

PCDHB5

466

Q9Y5E4
HVSNGAGSRETSLIV

HSPG2

2601

P98160
GHVSERTVIADGSLS

PALM2

216

Q8IXS6
LITVSDRDSGTNGHV

PCDHA2

371

Q9Y5H9
LAGDHECGSSSQRTL

LEMD3

541

Q9Y2U8
LSVSATDRDSGANGH

DCHS1

2396

Q96JQ0
TLAAESVSLSRHGGS

KIAA0100

751

Q14667
GTGTNLHRDISVSIS

PRKD1

551

Q15139
LSSEDGGDRLSTHEL

MPRIP

661

Q6WCQ1
GGDRLSTHELTSLLE

MPRIP

666

Q6WCQ1
EGSVHLASSRGTLSD

MADD

1226

Q8WXG6
LAGSAAEASHLVTDR

MDC1

1916

Q14676
AAGSSVLRELHTADS

KTI12

146

Q96EK9
SGHLLSAVTNRSDLG

LRRTM1

371

Q86UE6
DSASLSGESLDGHLQ

NAB2

411

Q15742
HLSTGDLLRSEVSSG

AK1

36

P00568
QLSRDGATGHVLLTD

PPFIA4

771

O75335
GSGDRAQRLGHSLSV

JCAD

1306

Q9P266
LHNSARGEVLGLSSS

HPS4

341

Q9NQG7
QRLLSQSFLGSEGSH

KCNH6

146

Q9H252
SEGANHTLLRFSAGD

BAIAP2L2

336

Q6UXY1
GLAGHLTLSDEDLTS

PLXNB3

1581

Q9ULL4
SSHLLRATSDGLAGV

PCDHGA9

721

Q9Y5G4
TRLLQDSLGGSAHSI

KIF22

326

Q14807
LHLTDIDSDSNRGSV

MYO18A

76

Q92614
NRGSVILDSGHLSTA

MYO18A

86

Q92614
DARSLTATGGNHVTA

FLNC

1276

Q14315
DSHGSVLRLSQALGN

NAXD

226

Q8IW45
ETLHAGRDTLCSLGQ

NOD1

451

Q9Y239
NKTEGSSLRDLLHSG

KDM3B

1286

Q7LBC6
LASGHSVRLGTSESL

PRKD2

201

Q9BZL6
AESIGESRLSENGKH

EXPH5

1651

Q8NEV8
ALLSLRLGSDAHGTE

IL10RA

11

Q13651
SHRLGIENSTLGESQ

FOXC2

456

Q99958
STVQSGGSHTALGDR

HEG1

491

Q9ULI3
HLEGTQREGVSSLDS

IRF7

461

Q92985
ASNSSHESRIGLAEG

PTPRZ1

1616

P23471
GHLVDVRGAETLSQS

PCDHB10

736

Q9UN67
GGSSLESSRHLSRSN

PITPNM2

631

Q9BZ72
HDNLRKSQGTSAEGS

GOLGA3

101

Q08378
GGSSDSSLALHERIQ

GOLGA3

1031

Q08378
ESRGTLGSRALSHDS

CRACDL

81

Q6NV74
AASLRQLEAGHSGRL

DSTYK

601

Q6XUX3
HSELDVRTAGANGTS

HPN

101

P05981
ADLDETGHLDSSGLQ

CDC25C

91

P30307
GASNRDLATLLSEHT

PPP1R3A

556

Q16821
ALHIGSVSATDRDSG

PCDHB4

466

Q9Y5E5
GESGSDVQLLAVSHR

MYO15B

1336

Q96JP2
GEASTSGQHSRLKLE

PRDM9

156

Q9NQV7
EIGSHRSSSSNLGAD

IRS2

636

Q9Y4H2
DNGLELDGSRHVATS

PXDNL

366

A1KZ92
HGDLREVSLTSSAQG

GOLGA8K

571

D6RF30
ELHLQISEAGRSSEG

C2CD2

326

Q9Y426
DVIDGGRASQLSTHL

CTNNA2

826

P26232
LDDSHGDQALSSGLS

CPEB3

411

Q8NE35
LRSSLLEHQGNESSA

CPLANE1

471

Q9H799
SLQSGLSEHEEGSLL

FBXO5

151

Q9UKT4
GESLLRSQSGHLESS

C3orf20

601

Q8ND61
SLFRDLDADGNGHLS

FSTL4

181

Q6MZW2
LDADGNGHLSSSELA

FSTL4

186

Q6MZW2
ISTGHLTSDNRGDIG

IL23R

341

Q5VWK5
QSRTLAGGIHATDLN

CST5

26

P28325
SELNHSSLGVGLDTL

CEP162

111

Q5TB80
LADSESLGHGAQRNT

BTBD7

1091

Q9P203
ELQTDGNRSSHSRLG

BID

56

P55957
REALSGVTSHGLSCE

DGKD

181

Q16760
DSRHVLSTGTDGCLN

NSMAF

816

Q92636
SSDSGGSIVRDSQRH

EPS8

661

Q12929
SLAADISHASDLVGG

E4F1

126

Q66K89
EGGHSLDSSLSVLRS

DPEP3

196

Q9H4B8
TAEVAGSSQTGLHRI

CCDC144A

1376

A2RUR9
SLHITDSKSGDGNRA

DIRAS3

86

O95661
SSILLGSNQGSDHSR

ZMYND8

1131

Q9ULU4
ALGSLRESEESIGTH

SAMD15

461

Q9P1V8
VISAGGNDSRSAHLR

SDK2

571

Q58EX2
DLGASSLHVNGESLE

EHMT1

331

Q9H9B1
DSDDGLHQFLRGTSS

BVES

301

Q8NE79
SHSARFLGTNGEELS

COL5A3

1666

P25940
LESIARQNGLGSHLS

MED1

81

Q15648
RQNGLGSHLSASGTE

MED1

86

Q15648
LSRRELDAAHTGTTG

PRR14L

1096

Q5THK1
GVSEASTGQRRLHSL

OSBPL7

341

Q9BZF2
LHIGSVSATDRDSGI

PCDHB6

466

Q9Y5E3
DTLHRLGAQGTGSQS

MROH5

1106

Q6ZUA9
TGGSDNHLILVDLRS

SHMT1

351

P34896
LGNSEDHTALSRALS

SNX2

351

O60749
LSAAGSSHGLVRSDA

TNRC6C

1616

Q9HCJ0
SHGQDAELSGTLSLV

RMND5A

46

Q9H871
GEGLSASRHSLRTGL

SLC4A7

251

Q9Y6M7
IQGLSHRNLLGDDTT

TMCO1

176

Q9UM00
QLNGGRTLVHSSSDG

TAB3

91

Q8N5C8
HADTGSIRSLQTGVG

PLD1

621

Q13393
GAGLSATIARSEHEI

NCOR1

366

O75376
GLRRQVSASELHTSG

EPPK1

4311

P58107
GEASTSGQHSRLKLE

PRDM7

156

Q9NQW5
TRLAVETAQGLDGHS

SEMA4A

416

Q9H3S1
AIGSVALDTARSHGE

SLC9B2

466

Q86UD5
GAADAHTASTLERGT

SPPL2C

551

Q8IUH8
LNHSDSESDVFSLGL

SHOC1

1221

Q5VXU9
LSFGHLEGSRQGSQS

SHROOM4

1186

Q9ULL8
TSLEDSFAHLQLSGD

RNF146

241

Q9NTX7
SALGSEVDGLNSLHS

MYCBP2

1706

O75592
AGLSLHDRRSSGSEE

PPP1R26

1151

Q5T8A7
RLGNTSEAHGAARTA

WIPF3

151

A6NGB9
SHLRQLGVAESESSG

WIZ

891

O95785
SSGISADLSRGHAVV

ITGAL

351

P20701
RGDTSGETLHSLIQQ

ARHGAP35

706

Q9NRY4
LNHRGGTESDLTVSR

SARDH

611

Q9UL12
AAREEILANGGSLSH

AGPS

601

O00116
LQGTDSECAGRLLHT

CIAO3

446

Q9H6Q4
LSQLESGSIAQHRGS

C11orf53

136

Q8IXP5
RHSGSLTRDNLSGLS

ATP11A

736

P98196
EVTRELLTSSQGTGH

SPG11

2056

Q96JI7
LRGREGGSHFINTSS

TBL1X

31

O60907
LLAFSSGRHGELTNS

RNF212

236

Q495C1
QLSSHGGLRSANRET

WNT8B

71

Q93098
SSTLAELNGGRGHAS

TRIP6

101

Q15654
SEHASIGSRLLAGST

UCP2

111

P55851
EASTHSGSRGDALNL

ZSCAN5DP

276

P0CG00
RETRTAGQSGLELHT

ZSCAN20

131

P17040
SRNHSATGEERTLGK

RGS12

1131

O14924
QHLLASADTGRDLTG

SPTBN2

661

O15020
RDSNHTSEGNGDSLL

STAG3

31

Q9UJ98
GVAHRSQSSEGVSSL

UBE4B

71

O95155
LTHSGNRGDALNLSS

ZSCAN5B

281

A6NJL1
VESLSDGSSHIAGDL

ZBTB18

141

Q99592
IDTGDSLSISCRGQH

FLT4

41

P35916
DELSLGHGRRDSSDS

PIEZO2

2056

Q9H5I5
GHGRRDSSDSLKSIN

PIEZO2

2061

Q9H5I5
ASTHSGNRGDALNLS

ZSCAN5A

281

Q9BUG6
FSLSGRGQSLDHDEA

SMTNL2

126

Q2TAL5
GGAHDLSSTARLLAQ

SPTBN4

686

Q9H254
GSTADVLHSRISGEI

VPS13C

2696

Q709C8
ETSAGQGLSSRESHA

PRAG1

516

Q86YV5
AGHRSAAASNLSGLS

PAM16

41

Q9Y3D7
SKEHSSGGTNLDRTN

USP37

276

Q86T82
DHQTGGLSIGASSRE

UBN1

626

Q9NPG3
NEGEKILSAGESSHR

ZNF594

86

Q96JF6
GGSLASHVARLESSD

PLEKHG2

1241

Q9H7P9
DHSLSREGSRQSLGS

USP31

1151

Q70CQ4
VVASSTGHLADSSRG

WNK2

2006

Q9Y3S1
REQLAESILHEGSTG

XPO6

871

Q96QU8
HLNNSRLSSESEGAG

ZNF831

196

Q5JPB2
GLRNGSSILIQDSHD

USP40

716

Q9NVE5
EEGRDTLGSSTNLHN

PJA2

126

O43164
ASTHSGSRGDALNLR

ZSCAN5C

281

A6NGD5
DSSDDNHSGTLGLSL

SKAP1

66

Q86WV1
EATSLEGALSGTRHS

TERT

281

O14746
NGTASALLHIDESAG

ZFY

371

P08048
LHTSNSGGRRELSEL

MZB1

71

Q8WU39
SSAVRGGVHSENLLS

NEUROD2

346

Q15784