Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent diacylglycerol kinase activity	DGKQ DGKD DGKH	5.93e-05	11	145	3	GO:0004143
GeneOntologyMolecularFunction	protein-folding chaperone binding	ATP7A TERT SLC12A2 LRP2 ATP1A2 RNF207 TBCD	1.77e-04	161	145	7	GO:0051087
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection assembly	ATP7A ITGA6 TOGARAM1 SAXO1 SH2B1 DNALI1 C2CD3 ALMS1 ARHGEF7 ANO6 RP1L1 PKHD1 KCNQ1 COBL PLD1 CPLANE1 ARHGEF6	4.13e-06	670	143	17	GO:0120031
GeneOntologyBiologicalProcess	cell projection assembly	ATP7A ITGA6 TOGARAM1 SAXO1 SH2B1 DNALI1 C2CD3 ALMS1 ARHGEF7 ANO6 RP1L1 PKHD1 KCNQ1 COBL PLD1 CPLANE1 ARHGEF6	5.54e-06	685	143	17	GO:0030031
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	ATP7A GDF2 TGFB2 C2CD3 AJAP1 SLC12A2 ALMS1 NFATC4 HS2ST1 PKHD1 LRP2 COBL CPLANE1 HECTD1 RNF207 FOXF1	6.41e-06	619	143	16	GO:0002009
GeneOntologyBiologicalProcess	neuron development	BOC SETX ATP7A KREMEN1 EPHA6 RB1 ITGA6 THOC2 TGFB2 PPP3CA ALMS1 NFATC4 RP1L1 KNDC1 LRP2 KCNQ1 COBL ELAVL4 TRPM1 HERC1 CTNND2 TNR SDK1 VPS13B PLXNA2 TBCD	7.86e-06	1463	143	26	GO:0048666
GeneOntologyBiologicalProcess	response to wounding	EPPK1 ATP7A KREMEN1 EPB41L4B CD109 MUC16 DGKQ DGKD DGKH TGFB2 PPP3CA AJAP1 SLC12A2 ANO6 TNR FOXF1	1.40e-05	659	143	16	GO:0009611
GeneOntologyBiologicalProcess	regulation of response to wounding	EPPK1 ATP7A KREMEN1 CD109 MUC16 AJAP1 SLC12A2 ANO6 TNR	2.11e-05	217	143	9	GO:1903034
GeneOntologyBiologicalProcess	negative regulation of response to wounding	EPPK1 KREMEN1 CD109 MUC16 AJAP1 SLC12A2 TNR	2.82e-05	126	143	7	GO:1903035
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	GDF2 TGFB2 C2CD3 SLC12A2 NFATC4 HS2ST1 PKHD1 LRP2 COBL HECTD1 RNF207 FOXF1	3.82e-05	421	143	12	GO:0060562
GeneOntologyBiologicalProcess	lipid phosphorylation	DGKQ DGKD DGKH	5.17e-05	11	143	3	GO:0046834
GeneOntologyBiologicalProcess	tissue morphogenesis	ATP7A GDF2 TGFB2 C2CD3 AJAP1 SLC12A2 ALMS1 NFATC4 HS2ST1 PKHD1 LRP2 COBL CPLANE1 HECTD1 RNF207 FOXF1	6.61e-05	750	143	16	GO:0048729
GeneOntologyBiologicalProcess	neuron projection development	BOC SETX ATP7A KREMEN1 EPHA6 RB1 ITGA6 THOC2 TGFB2 PPP3CA ALMS1 NFATC4 KNDC1 LRP2 COBL ELAVL4 HERC1 CTNND2 TNR SDK1 VPS13B PLXNA2	7.53e-05	1285	143	22	GO:0031175
GeneOntologyBiologicalProcess	phosphatidic acid biosynthetic process	DGKQ DGKD DGKH PLD1	1.10e-04	36	143	4	GO:0006654
GeneOntologyBiologicalProcess	cardiac muscle thin filament assembly	NEBL NEB	1.43e-04	3	143	2	GO:0071691
GeneOntologyBiologicalProcess	morphogenesis of a polarized epithelium	AJAP1 ALMS1 PKHD1 CPLANE1 FOXF1	1.54e-04	73	143	5	GO:0001738
GeneOntologyBiologicalProcess	sensory perception	SPATA7 DMXL2 RTP2 OR5B21 OR14I1 TAAR5 OR1L3 TULP2 TGFBI SLC12A2 ALMS1 RP1L1 OR1E2 LRP2 OR1G1 KCNQ1 TRPM1 OLFM2 SLC24A1	1.57e-04	1072	143	19	GO:0007600
GeneOntologyBiologicalProcess	wound healing	EPPK1 EPB41L4B CD109 MUC16 DGKQ DGKD DGKH TGFB2 PPP3CA AJAP1 SLC12A2 ANO6	1.70e-04	493	143	12	GO:0042060
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	ABCB7 SETX ATP7A RB1 ITGA6 TOGARAM1 DGKD UFL1 SAXO1 GDF2 SH2B1 TGFB2 PPP3CA ALMS1 ARHGEF7 ANO6 NAV3 LRP2 COBL ELAVL4 ADGRL2 PLXNA2	1.82e-04	1366	143	22	GO:0051130
GeneOntologyBiologicalProcess	phosphatidic acid metabolic process	DGKQ DGKD DGKH PLD1	1.84e-04	41	143	4	GO:0046473
GeneOntologyBiologicalProcess	epithelium development	EPPK1 ATP7A RBBP6 CD109 GDF2 POF1B TGFB2 C2CD3 PPP3CA AJAP1 SLC12A2 ALMS1 NFATC4 HS2ST1 PKHD1 LRP2 KCNQ1 COBL CPLANE1 HECTD1 RNF207 PLXNA2 FOXF1	1.93e-04	1469	143	23	GO:0060429
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	NPR3 SDK2 ATP7A NEBL CD109 NEB GDF2 TERT TGFB2 SLC12A2 NFATC4 SPACA1 HS2ST1 KNDC1 LRP2 COBL HERC1 HECTD1 EIF2AK3 SDK1 VPS13B PLXNA2 FOXF1	2.21e-04	1483	143	23	GO:0048646
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	BOC ATP7A EPHA6 RB1 TGFB2 PPP3CA NFATC4 KNDC1 LRP2 COBL ELAVL4 CTNND2 TNR PLXNA2 TBCD	2.22e-04	748	143	15	GO:0048667
MousePheno	abnormal renal tubule epithelial cell primary cilium morphology	GLIS3 ALMS1 PKHD1 CPLANE1	8.97e-06	16	121	4	MP:0011066
MousePheno	abnormal nonmotile primary cilium morphology	SPATA7 GLIS3 ALMS1 PKHD1 COBL CPLANE1	3.10e-05	70	121	6	MP:0013205
MousePheno	abnormal kidney epithelial cell primary cilium morphology	GLIS3 ALMS1 PKHD1 CPLANE1	4.16e-05	23	121	4	MP:0011065
MousePheno	abnormal renal tubule epithelium morphology	GLIS3 TGFB2 ALMS1 PKHD1 CPLANE1	5.69e-05	48	121	5	MP:0009640
MousePheno	abnormal primary cilium morphology	SPATA7 GLIS3 C2CD3 ALMS1 PKHD1 COBL CPLANE1	5.85e-05	114	121	7	MP:0013203
MousePheno	abnormal interdental cell morphology	TGFB2 SLC12A2	7.43e-05	2	121	2	MP:0004482
Domain	DAGK_acc	DGKQ DGKD DGKH	5.28e-05	10	145	3	PF00609
Domain	Diacylglycerol_kin_accessory	DGKQ DGKD DGKH	5.28e-05	10	145	3	IPR000756
Domain	DAGKa	DGKQ DGKD DGKH	5.28e-05	10	145	3	SM00045
Domain	DAGKc	DGKQ DGKD DGKH	1.57e-04	14	145	3	SM00046
Domain	Diacylglycerol_kinase_cat_dom	DGKQ DGKD DGKH	1.95e-04	15	145	3	IPR001206
Domain	DAGK	DGKQ DGKD DGKH	1.95e-04	15	145	3	PS50146
Domain	DAGK_cat	DGKQ DGKD DGKH	1.95e-04	15	145	3	PF00781
Domain	NAD/diacylglycerol_kinase	DGKQ DGKD DGKH	2.88e-04	17	145	3	IPR016064
Domain	ARM-type_fold	USP24 TOGARAM1 RALGAPA2 THADA MROH8 CTNND2 HECTD1 TBCD ARMC6 XPO7	3.22e-04	339	145	10	IPR016024
Domain	Nebulin	NEBL NEB	3.56e-04	4	145	2	PF00880
Domain	NEBULIN	NEBL NEB	3.56e-04	4	145	2	PS51216
Domain	NEBU	NEBL NEB	3.56e-04	4	145	2	SM00227
Domain	Nebulin	NEBL NEB	3.56e-04	4	145	2	IPR013998
Domain	Nebulin_repeat	NEBL NEB	3.56e-04	4	145	2	IPR000900
Domain	GPCR_2_latrophilin	OLFM2 ADGRL2	5.89e-04	5	145	2	IPR003924
Domain	HMG_box	HBP1 CIC BBX HMGXB3	7.60e-04	53	145	4	PF00505
Domain	HMG_BOX_2	HBP1 CIC BBX HMGXB3	8.15e-04	54	145	4	PS50118
Domain	HMG	HBP1 CIC BBX HMGXB3	8.15e-04	54	145	4	SM00398
Domain	-	HBP1 CIC BBX HMGXB3	8.74e-04	55	145	4	1.10.30.10
Domain	C1_1	DGKQ DGKD DGKH RASGRP1	1.00e-03	57	145	4	PF00130
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	DGKQ DGKD DGKH RASGRP1	4.31e-05	27	104	4	M12123
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SPATA7 GAPVD1 SETX ATP7A EPB41L4B MUC16 THADA PPP3CA BBX SLC12A2 ANO6 MKI67 PLD1 ADGRL2 MGA SDK1 XPO7	3.64e-08	777	147	17	35844135
Pubmed	Evaluations of the selectivities of the diacylglycerol kinase inhibitors R59022 and R59949 among diacylglycerol kinase isozymes using a new non-radioactive assay method.	DGKQ DGKD DGKH	7.40e-08	3	147	3	23949095
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	GAPVD1 ABCB7 SETX ESS2 RB1 UFL1 CIC SH2B1 BBX PHF20L1 NFATC4 ADGRL2 MGA EIF2AK3 FOXF1 ARMC6 XPO7	1.47e-07	857	147	17	25609649
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SECISBP2L DMXL2 TOGARAM1 DGKD RALGAPA2 GALNT16 SH2B1 THADA ALMS1 ADGRF5 MGA HECTD1	1.37e-06	493	147	12	15368895
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	DMXL2 CTU2 GAPVD1 ESS2 ITGA6 UFL1 TUBGCP2 POF1B CIC THADA TADA2B MGA FOXF1 TBCD	1.49e-06	689	147	14	36543142
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ATP7A SRSF2 EPB41L4B DGKD RALGAPA2 THADA SLC12A2 ARHGEF7 EIF2B1 CENPI COBL PLD1 HERC1 TBCD	2.44e-06	719	147	14	35337019
Pubmed	A human MAP kinase interactome.	DLGAP1 SETX RBBP6 NEB LCP2 CIC ARHGEF7 NAV3 COBL CPLANE1 MGA	7.62e-06	486	147	11	20936779
Pubmed	A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.	GLIS3 RASGRP1 KCNQ1	8.69e-06	10	147	3	22961080
Pubmed	Spatial and temporal regulation of coronary vessel formation by calcineurin-NFAT signaling.	PPP3CA NFATC4 MKI67	8.69e-06	10	147	3	19710169
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	DMXL2 ATP7A SLC35E1 ITGA6 SLC12A2 ANO6 LRP2 PLD1 ADGRL2 EIF2AK3 VPS13B	1.07e-05	504	147	11	34432599
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	GAPVD1 TMEM59 USP24 RDH14 SLC35E1 UFL1 DCAF16 TUBGCP2 THADA SLC12A2 HS2ST1 ADGRL2 HECTD1 TBCD XPO7	1.18e-05	942	147	15	31073040
Pubmed	Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.	DGKQ DGKD DGKH	1.19e-05	11	147	3	17021016
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NPR3 ABCB7 TMEM59 CD109 SLC35E1 ITGA6 TGFB2 TMX2 TGFBI IGSF10 THADA PTPN12 SLC12A2 ANO6 HS2ST1 HECTD1 EIF2AK3	1.39e-05	1201	147	17	35696571
Pubmed	Identification and characterization of two splice variants of human diacylglycerol kinase eta.	DGKD DGKH	1.77e-05	2	147	2	12810723
Pubmed	Molecules in focus: diacylglycerol kinase.	DGKQ DGKH	1.77e-05	2	147	2	9438377
Pubmed	Sidekick-1 is upregulated in glomeruli in HIV-associated nephropathy.	SDK2 SDK1	1.77e-05	2	147	2	15213259
Pubmed	Definition of the critical domains required for homophilic targeting of mouse sidekick molecules.	SDK2 SDK1	1.77e-05	2	147	2	15703275
Pubmed	Architecture of cell-cell adhesion mediated by sidekicks.	SDK2 SDK1	1.77e-05	2	147	2	30150416
Pubmed	TERT promoter mutations and Ki-67 labeling index as a prognostic marker of papillary thyroid carcinomas: combination of two independent factors.	TERT MKI67	1.77e-05	2	147	2	28150740
Pubmed	Up-regulation of TGFBI and TGFB2 in the plasma of gestational diabetes mellitus patients and its clinical significance.	TGFB2 TGFBI	1.77e-05	2	147	2	34792732
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	1.77e-05	2	147	2	19851499
Pubmed	The hTERT-protein and Ki-67 labelling index in recurrent and non-recurrent meningiomas.	TERT MKI67	1.77e-05	2	147	2	15679862
Pubmed	Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1.	SLC12A2 ATP1A2	1.77e-05	2	147	2	17674100
Pubmed	Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases.	DGKQ DGKD	1.77e-05	2	147	2	8626538
Pubmed	[Role of ion channel Na-K-2Cl and alpha2 Na, K-ATPase in cochlear potassium cycling and auditory function].	SLC12A2 ATP1A2	1.77e-05	2	147	2	17111813
Pubmed	Sidekicks: synaptic adhesion molecules that promote lamina-specific connectivity in the retina.	SDK2 SDK1	1.77e-05	2	147	2	12230981
Pubmed	[Association of age-related hearing loss with ion transporter KCNQ1 and NKCC1 in cochlea of C57BL/6J mice].	SLC12A2 KCNQ1	1.77e-05	2	147	2	21426709
Pubmed	Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis.	TERT MKI67	1.77e-05	2	147	2	35187889
Pubmed	Molecular basis of sidekick-mediated cell-cell adhesion and specificity.	SDK2 SDK1	1.77e-05	2	147	2	27644106
Pubmed	Initial Suppression of Transforming Growth Factor-β Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia.	TGFB2 TGFBI MKI67	2.05e-05	13	147	3	26878215
Pubmed	Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.	EPHA6 PPP3CA NFATC4 MKI67	3.03e-05	42	147	4	11439183
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	EPPK1 RBBP6 THOC2 PKHD1 LRP2 COBL TRPM1	3.10e-05	208	147	7	33230847
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	SLC7A13 NEBL STXBP5L VPS50 DGKH RALGAPA2 IGSF10 PHF20L1 ELAVL4 PLD1 NCR2 VPS13B	3.75e-05	686	147	12	29987050
Pubmed	Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in retina.	MKI67 ELAVL4 TRPM1	3.98e-05	16	147	3	29559301
Pubmed	USP40 deubiquitinates HINT1 and stabilizes p53 in podocyte damage.	SRSF2 HEBP2 ITGA6 LRP2	3.99e-05	45	147	4	35605301
Pubmed	A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.	SDK2 EPHA6 TGFB2 SDK1 PLXNA2	4.37e-05	91	147	5	28558017
Pubmed	IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.	GAPVD1 USP24 TUBGCP2 GTPBP1 EIF2B1 HECTD1 ARMC6	4.56e-05	221	147	7	31950832
Pubmed	Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium.	NEB TGFB2 MKI67	4.82e-05	17	147	3	34622152
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GAPVD1 ABCB7 DSG1 RB1 RBBP6 SLC35E1 ITGA6 THOC2 TMX2 ZNF263 SLC12A2 CENPI MKI67 MGA TBCD XPO7	5.31e-05	1203	147	16	29180619
Pubmed	The p16(INK4A)/pRb pathway and telomerase activity define a subgroup of Ph+ adult Acute Lymphoblastic Leukemia associated with inferior outcome.	RB1 TERT	5.31e-05	3	147	2	25675863
Pubmed	KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling.	RB1 MKI67	5.31e-05	3	147	2	34724040
Pubmed	Predicting Lymph Node Metastasis in Endometrial Cancer Using Serum CA125 Combined with Immunohistochemical Markers PR and Ki67, and a Comparison with Other Prediction Models.	MUC16 MKI67	5.31e-05	3	147	2	27163153
Pubmed	Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response.	LAMP3 EIF2AK3	5.31e-05	3	147	2	23294542
Pubmed	Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome.	SRSF2 TERT	5.31e-05	3	147	2	25965571
Pubmed	Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.	RB1 TERT	5.31e-05	3	147	2	12508351
Pubmed	Diacylglycerol kinase-theta is localized in the speckle domains of the nucleus.	SRSF2 DGKQ	5.31e-05	3	147	2	12799190
Pubmed	Biomarkers distinguishing mammary fibroepithelial neoplasms: a tissue microarray study.	RB1 MKI67	5.31e-05	3	147	2	25003838
Pubmed	Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway.	RB1 TERT	5.31e-05	3	147	2	16619045
Pubmed	Human telomerase accelerates growth of lens epithelial cells through regulation of the genes mediating RB/E2F pathway.	RB1 TERT	5.31e-05	3	147	2	12032846
Pubmed	RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs.	RASGRP1 ARHGEF6	5.31e-05	3	147	2	9582122
Pubmed	Association study of MCCC1/LAMP3 and DGKQ variants with Parkinson's disease in patients of Malay ancestry.	DGKQ LAMP3	5.31e-05	3	147	2	33559030
Pubmed	PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.	CTNND2 PDZD2	5.31e-05	3	147	2	10896674
Pubmed	Inactivation of p16INK4a, with retention of pRB and p53/p21cip1 function, in human MRC5 fibroblasts that overcome a telomere-independent crisis during immortalization.	RB1 TERT	5.31e-05	3	147	2	15308640
Pubmed	Transforming growth factor-beta-inducible gene-h3 (beta(ig)-h3) promotes cell adhesion of human astrocytoma cells in vitro: implication of alpha6beta4 integrin.	ITGA6 TGFBI	5.31e-05	3	147	2	12499048
Pubmed	Expression of pRb, Ki67 and HER 2/neu in gastric carcinomas: Relation to different histopathological grades and stages.	RB1 MKI67	5.31e-05	3	147	2	28965621
Pubmed	Simultaneously reduced NKCC1 and Na,K-ATPase expression in murine cochlear lateral wall contribute to conservation of endocochlear potential following a sensorineural hearing loss.	SLC12A2 ATP1A2	5.31e-05	3	147	2	21094218
Pubmed	Calcineurin interacts with PERK and dephosphorylates calnexin to relieve ER stress in mammals and frogs.	PPP3CA EIF2AK3	5.31e-05	3	147	2	20700529
Pubmed	[Expression and significance of hTERT, c-myc and Ki-67 in hepatocellular carcinoma].	TERT MKI67	5.31e-05	3	147	2	19351506
Pubmed	The HMG-box transcription factor HBP1 is targeted by the pocket proteins and E1A.	RB1 HBP1	5.31e-05	3	147	2	9178770
Pubmed	Temporal regulation of nuclear factor one occupancy by calcineurin/NFAT governs a voltage-sensitive developmental switch in late maturing neurons.	PPP3CA NFATC4	5.31e-05	3	147	2	23407945
Pubmed	The HBP1 transcriptional repressor participates in RAS-induced premature senescence.	RB1 HBP1	5.31e-05	3	147	2	16966377
Pubmed	Mitogen-activated protein kinase p38 and retinoblastoma protein signalling is required for DNA damage-mediated formation of senescence-associated heterochromatic foci in tumour cells.	RB1 HBP1	5.31e-05	3	147	2	23859194
Pubmed	Tubal metaplasia of the endometrium with cytologic atypia: analysis of p53, Ki-67, TERT, and long-term follow-up.	TERT MKI67	5.31e-05	3	147	2	21572399
Pubmed	Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway.	PPP3CA NFATC4	5.31e-05	3	147	2	22164265
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	GAPVD1 SRSF2 DSG1 RB1 PPP3CA INTS11 MKI67 HECTD1 TBCD	5.49e-05	400	147	9	35013556
Pubmed	Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.	CD109 DGKD DGKH	5.76e-05	18	147	3	24068962
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EPHA6 EPB41L4B HEBP2 STXBP5L DGKH SH2B1 THADA PPP3CA HS2ST1 KNDC1 CDYL2 COBL OLFM2 HECTD1 VPS13B TBCD PDZD2 XPO7	6.08e-05	1489	147	18	28611215
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	GAPVD1 ESS2 NEBL VPS50 SLC35E1 TUBGCP2 SLC12A2 ALMS1 NFATC4 EIF2B1 MGA HECTD1	7.06e-05	733	147	12	34672954
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	UFL1 ADGRF5 ATP1A2 ADGRL2 XPO7	7.20e-05	101	147	5	9872452
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ATP7A EPB41L4B ITGA6 UFL1 RALGAPA2 ZDHHC20 SLC12A2 COBL ADGRL2	8.11e-05	421	147	9	36976175
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	RB1 RBBP6 VPS50 DCAF16 TUBGCP2 RALGAPA2 THADA ALMS1 TADA2B INTS11 LRP2 PLD1 ADGRL2 MGA ARMC6	8.18e-05	1116	147	15	31753913
Pubmed	Harnessing host enhancers of SARS-CoV-2 entry as novel targets for antiviral therapy.	CD109 ITGA6 TGFBI ANO6	8.84e-05	55	147	4	38945485
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GAPVD1 SDK2 SETX VPS50 UFL1 ARHGEF7 HS2ST1 HMGXB3 ATP1A2 ADGRL2	9.01e-05	529	147	10	14621295
Pubmed	Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.	GLIS3 PKHD1 LRP2	9.30e-05	21	147	3	27591083
Pubmed	Mice Lacking Hbp1 Function Are Viable and Fertile.	RB1 HBP1 MKI67	9.30e-05	21	147	3	28107452
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	EPPK1 ESS2 RBBP6 GLIS3 CIC SH2B1 SLC12A2 NFATC4 MGA	9.52e-05	430	147	9	35044719
Pubmed	PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	9659915
Pubmed	A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	10428811
Pubmed	The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	15649357
Pubmed	Upper aerodigestive tract squamous dysplasia: correlation with p16, p53, pRb, and Ki-67 expression.	RB1 MKI67	1.06e-04	4	147	2	16948516
Pubmed	Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development.	GDF2 MKI67	1.06e-04	4	147	2	23812757
Pubmed	Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.	LRP2 KCNQ1	1.06e-04	4	147	2	16901941
Pubmed	Differential expression of cyclin D1, Ki‑67, pRb, and p53 in psoriatic skin lesions and normal skin.	RB1 MKI67	1.06e-04	4	147	2	29115643
Pubmed	Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component.	TGFB2 MKI67	1.06e-04	4	147	2	19587023
Pubmed	Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	12499396
Pubmed	Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.	RB1 MKI67	1.06e-04	4	147	2	17442359
Pubmed	The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	12935897
Pubmed	Developmental regulation of the mouse IGF-I exon 1 promoter region by calcineurin activation of NFAT in skeletal muscle.	PPP3CA NFATC4	1.06e-04	4	147	2	17229811
Pubmed	Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	15306850
Pubmed	Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin.	DGKQ DGKD	1.06e-04	4	147	2	11309392
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	NEBL NEB	1.06e-04	4	147	2	23985323
Pubmed	Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.	ARHGEF7 ARHGEF6	1.06e-04	4	147	2	27182061
Pubmed	Neuritin Up-regulates Kv4.2 α-Subunit of Potassium Channel Expression and Affects Neuronal Excitability by Regulating the Calcium-Calcineurin-NFATc4 Signaling Pathway.	PPP3CA NFATC4	1.06e-04	4	147	2	27307045
Pubmed	SHP-2 and PTP-pest induction during Rb-E2F associated apoptosis.	RB1 PTPN12	1.06e-04	4	147	2	22644489
Pubmed	Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman.	SLC12A2 ATP1A2	1.06e-04	4	147	2	19570895
Pubmed	A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese.	TERT MTMR3	1.06e-04	4	147	2	21725308
Pubmed	The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion.	TMEM59 SLC35E1 ITGA6 TMX2 ANO6 EIF2AK3	1.08e-04	176	147	6	28692057
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	DLGAP1 DMXL2 STXBP5L GTPBP1 PPP3CA ARHGEF7 ATP1A2 CTNND2	1.21e-04	347	147	8	17114649
Pubmed	Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice.	RB1 TGFB2 MKI67	1.23e-04	23	147	3	19864318
Pubmed	Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.	EPHA6 ELAVL4 PLXNA2	1.23e-04	23	147	3	24360543
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKQ DGKD DGKH	2.09e-05	10	103	3	1178
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	DGKD DGKH SH2B1 ARHGEF7 PLD1 ARHGEF6	1.16e-03	206	103	6	682
GeneFamily	Olfactory receptors, family 1	OR1L3 OR1E2 OR1G1	1.52e-03	40	103	3	147
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	THADA CTNND2 ARMC6	1.88e-03	43	103	3	409
GeneFamily	Fibronectin type III domain containing	BOC SDK2 EPHA6 TNR SDK1	2.22e-03	160	103	5	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	BOC SDK2 IGSF10 ADGRF5 SDK1	2.28e-03	161	103	5	593
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	USP24 TOGARAM1 BBX AJAP1 ARHGEF7 MKI67 NAV3 ADGRL2 VPS13B	1.14e-07	145	144	9	M1810
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SECISBP2L CDK17 DMXL2 GAPVD1 SETX RB1 USP24 ITGA6 TOGARAM1 THOC2 TGFB2 C2CD3 PTPN12 BBX ARHGEF7 MTMR3 NAV3 VPS13B	1.15e-06	856	144	18	M4500
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	GAPVD1 USP24 TOGARAM1 BBX AJAP1 ARHGEF7 MKI67 NAV3 ADGRL2 VPS13B	6.61e-06	300	144	10	M8702
Coexpression	GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN	CDK17 ATP7A DSG1 STXBP5L TOGARAM1 BBX PHF20L1 PLXNA2	1.44e-05	198	144	8	M9346
Coexpression	GABRIELY_MIR21_TARGETS	GAPVD1 THOC2 TGFB2 RASGRP1 PHF20L1 PLD1 MGA HECTD1 EIF2AK3	3.30e-05	289	144	9	M2196
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_500	DMXL2 ATP7A ITGA6 NEB THOC2 RASGRP1 SLC12A2 SPACA1 ARHGEF7 HERC1 CPLANE1 MGA DYNC1I1 ZNF541	2.63e-07	387	139	14	gudmap_developingGonad_e18.5_ovary_500
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#1_top-relative-expression-ranked_500	DMXL2 ITGA6 RASGRP1 SPACA1 ARHGEF7 HERC1 DYNC1I1 ZNF541	2.87e-06	134	139	8	gudmap_developingGonad_e18.5_ovary_500_k1
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	DMXL2 GAPVD1 ATP7A ITGA6 DGKD THOC2 TULP2 RASGRP1 PTPN12 BBX SLC12A2 ALMS1 SPACA1 HERC1 CPLANE1 MGA DYNC1I1 ZNF541	3.27e-06	776	139	18	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	DMXL2 RB1 ALMS1 SPACA1 HERC1 CPLANE1 MGA	8.03e-06	110	139	7	gudmap_dev gonad_e13.5_M_GermCell_Oct_k4_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	NPR3 NEBL EPB41L4B HEBP2 RBBP6 CD109 GLIS3 ITGA6 POF1B TGFB2 C2CD3 NFATC4 NAV3 TRPM1 CTNND2 CPLANE1 DYNC1I1	1.17e-05	769	139	17	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000	DMXL2 ATP7A ITGA6 DGKD NEB THOC2 TULP2 RASGRP1 BBX SLC12A2 SPACA1 ARHGEF7 HERC1 CPLANE1 MGA DYNC1I1 ZNF541	1.36e-05	778	139	17	gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000	DMXL2 GAPVD1 ATP7A ITGA6 THOC2 TULP2 RASGRP1 BBX SLC12A2 SPACA1 ARHGEF7 HERC1 CPLANE1 MGA DYNC1I1 ZNF541	6.62e-05	795	139	16	gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlas	DevelopingGonad_e18.5_ovary_emap-12283_k-means-cluster#5_top-relative-expression-ranked_1000	DMXL2 ITGA6 RASGRP1 SPACA1 ARHGEF7 HERC1 DYNC1I1 ZNF541	1.40e-04	230	139	8	gudmap_developingGonad_e18.5_ovary_1000_k5
ToppCell	(6)_Endothelial_cells-(6)_Endothelial-E\|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	NPR3 CD109 ITGA6 DGKH SLC12A2 ADGRF5 ADGRL2 FOXF1	1.14e-07	174	146	8	4a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPR3 CD109 ITGA6 DGKH SLC12A2 ADGRF5 ADGRL2 FOXF1	1.90e-07	186	146	8	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPR3 CD109 ITGA6 DGKH SLC12A2 ADGRF5 ADGRL2 FOXF1	1.90e-07	186	146	8	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 NPR3 EPHA6 GLIS3 AJAP1 PKHD1 LRP2 SDK1	2.15e-07	189	146	8	28b502611829e4a24caff2562545c7db97686099
ToppCell	COVID-19-Endothelial_cells-Inflamed_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	CDK17 CD109 ITGA6 RALGAPA2 ADGRF5 ADGRL2 PLXNA2 FOXF1	2.52e-07	193	146	8	979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NPR3 ITGA6 DGKH RALGAPA2 NAV3 ADGRF5 ADGRL2 FOXF1	2.52e-07	193	146	8	ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 DGKH NAV3 ADGRF5 ADGRL2 FOXF1	2.62e-07	194	146	8	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	Fetal_29-31_weeks-Endothelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 DGKH RALGAPA2 ADGRF5 ADGRL2 FOXF1	2.83e-07	196	146	8	3981f6c7487598f4f7ce4650ac0ac5bd41481d66
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 DGKH RALGAPA2 ADGRF5 ADGRL2 FOXF1	2.95e-07	197	146	8	6a3c647af41fea923311562575a0d656fbc13cbe
ToppCell	COVID-19-lung-Capillary_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CDK17 CD109 ITGA6 RALGAPA2 PLA1A ADGRF5 ADGRL2 FOXF1	3.06e-07	198	146	8	45419f2804b4be79bae6632e71c54e1af482d115
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NPR3 SETX ITGA6 DGKH RALGAPA2 PPP3CA ADGRF5 ADGRL2	3.30e-07	200	146	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDK2 NEBL TROAP CD109 PTGDS TGFB2 DYNC1I1	1.35e-06	167	146	7	102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 NEBL IGSF10 NWD2 NAV3 SDK1	2.22e-06	180	146	7	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC CDK17 CD109 ARHGEF7 ADGRF5 ADGRL2 TBCD	2.22e-06	180	146	7	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	LV\|World / Chamber and Cluster_Paper	NEBL SPHKAP ATP1A2 CTNND2 ADGRL2 RNF207 PDZD2	2.22e-06	180	146	7	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 SDK2 NEBL IGSF10 NWD2 NAV3 SDK1	2.22e-06	180	146	7	9b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L NEB PKHD1 NAV3 LRP2 ELAVL4 SDK1	2.56e-06	184	146	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L NEB PKHD1 NAV3 LRP2 ELAVL4 SDK1	2.56e-06	184	146	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STXBP5L NEB PKHD1 NAV3 LRP2 ELAVL4 SDK1	2.56e-06	184	146	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-Endothelial_cells-Endothelial_cells_(general)\|Control / group, cell type (main and fine annotations)	NPR3 CD109 RALGAPA2 NAV3 ADGRF5 ADGRL2 TNR	2.85e-06	187	146	7	fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 DGKH NAV3 ADGRF5 ADGRL2	2.96e-06	188	146	7	117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCell	COVID-19-Endothelial_cells-Endothelial_cells_(general)\|COVID-19 / group, cell type (main and fine annotations)	NPR3 ITGA6 RALGAPA2 ADGRF5 ADGRL2 PLXNA2 FOXF1	3.17e-06	190	146	7	812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	NEBL SPHKAP ATP1A2 CTNND2 ADGRL2 RNF207 PDZD2	3.17e-06	190	146	7	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	Control-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	NPR3 CD109 ITGA6 DGKH ADGRF5 ADGRL2 FOXF1	3.17e-06	190	146	7	7f3f419fffe02934b6f27b697f7a6401072491ed
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CDK17 ITGA6 SLC12A2 ARHGEF7 ADGRF5 PLXNA2 PDZD2	3.17e-06	190	146	7	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	367C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPR3 CD109 TGFB2 KCNQ1 ADGRF5 ADGRL2 FOXF1	3.51e-06	193	146	7	5c6b03d6d98aa873fda1a201d44a912246bb5a92
ToppCell	LPS-antiTNF-Endothelial-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD109 ITGA6 DGKH SLC12A2 ADGRF5 CTNND2 ADGRL2	3.51e-06	193	146	7	02f633b016ab19bfa65bfd0cf32f000549a62148
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR3 CD109 ITGA6 DGKH ADGRF5 CTNND2 ADGRL2	3.51e-06	193	146	7	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR3 CD109 ITGA6 ADGRF5 CTNND2 ADGRL2 DYNC1I1	3.51e-06	193	146	7	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPR3 ITGA6 DGKH RALGAPA2 PPP3CA NAV3 CTNND2	3.51e-06	193	146	7	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	LPS-antiTNF-Endothelial\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD109 ITGA6 DGKH SLC12A2 ADGRF5 CTNND2 ADGRL2	3.51e-06	193	146	7	5122b1ffba42de190061be34ecdc6176f84e56a3
ToppCell	367C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NPR3 CD109 TGFB2 KCNQ1 ADGRF5 ADGRL2 FOXF1	3.51e-06	193	146	7	d4b58eee97043b4337ec36c40f9af6499d864df9
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 NAV3 ADGRF5 ADGRL2 FOXF1	3.64e-06	194	146	7	71ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 NEBL ITGA6 PKHD1 LRP2 COBL SDK1	3.64e-06	194	146	7	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 PLA1A ADGRF5 ADGRL2 FOXF1	3.64e-06	194	146	7	40842a7160f337bfc191ee15fbda3e3d38a04c57
ToppCell	367C-Endothelial_cells-Endothelial-E-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NPR3 CD109 ITGA6 PLA1A ADGRF5 ADGRL2 FOXF1	3.76e-06	195	146	7	65fc50e3818e902028fc4226070fa57609c66b9c
ToppCell	367C-Endothelial_cells-Endothelial-E\|367C / Donor, Lineage, Cell class and subclass (all cells)	NPR3 CD109 ITGA6 PLA1A ADGRF5 ADGRL2 FOXF1	3.76e-06	195	146	7	3b79e6bb525b17192ecec9e1227a29c419968144
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NPR3 CD109 ITGA6 RALGAPA2 ADGRF5 ADGRL2 FOXF1	3.89e-06	196	146	7	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	Endothelial-capillary_endothelial_cell_(Cap1)\|World / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 DGKH ADGRF5 ADGRL2 FOXF1	3.89e-06	196	146	7	0ce3ed27d2b9276390952652c17a8d6de13add36
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	CD109 ITGA6 DGKH NAV3 ADGRF5 ADGRL2 FOXF1	4.02e-06	197	146	7	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Fetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 DGKH ADGRF5 ADGRL2 FOXF1	4.02e-06	197	146	7	b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-intermediate_cap\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NPR3 CD109 ITGA6 DGKH ADGRF5 ADGRL2 FOXF1	4.16e-06	198	146	7	a75499f8f1630359b64717c300621aa3b1ab44d4
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEBL EPB41L4B HEBP2 MUC16 DGKH DNALI1 CPLANE1	4.16e-06	198	146	7	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	CDK17 NPR3 CD109 ITGA6 RALGAPA2 ADGRF5 ADGRL2	4.30e-06	199	146	7	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 STXBP5L GLIS3 OR14I1 NWD2 ADGRF5 PDZD2	4.44e-06	200	146	7	9c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCell	medial-Endothelial-Capillary\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NPR3 CD109 ITGA6 RALGAPA2 ADGRF5 ADGRL2 FOXF1	4.44e-06	200	146	7	fd4dcdc67db2a5dbdd54bd2ae975c66df904d4d8
ToppCell	Parenchyma_COVID-19-Endothelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	NPR3 ITGA6 RALGAPA2 PLA1A ADGRF5 ADGRL2 FOXF1	4.44e-06	200	146	7	abcbd5a156aa4fd51d284441388975c81c0b88ae
ToppCell	medial-2-Endothelial-Capillary\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NPR3 CD109 ITGA6 RALGAPA2 ADGRF5 ADGRL2 FOXF1	4.44e-06	200	146	7	e4f390dfd4dd25600f0f7a17c5523283a5966e92
ToppCell	medial-Endothelial-Capillary-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NPR3 CD109 ITGA6 RALGAPA2 ADGRF5 ADGRL2 FOXF1	4.44e-06	200	146	7	4291b5453e98e20ec8150a96ccc865a5964bc645
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / Treatment groups by lineage, cell group, cell type	SETX ITGA6 PPP3CA SLC12A2 ADGRF5 CTNND2 ADGRL2	4.44e-06	200	146	7	b1fadb2b5e37e0f51e079d8409c2647eef68dc3b
ToppCell	Lung_Parenchyma-Severe-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NPR3 ITGA6 RALGAPA2 PLA1A ADGRF5 ADGRL2 FOXF1	4.44e-06	200	146	7	d9d0ffa18e5b4647966e19ad9830cbba6120677e
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 STXBP5L GLIS3 OR14I1 NWD2 ADGRF5 PDZD2	4.44e-06	200	146	7	8821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SETX CD109 ITGA6 PPP3CA SLC12A2 ADGRF5 ADGRL2	4.44e-06	200	146	7	a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SETX ITGA6 PPP3CA SLC12A2 ADGRF5 CTNND2 ADGRL2	4.44e-06	200	146	7	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	Biopsy_Control_(H.)-Endothelial\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	NPR3 CD109 ITGA6 PTGDS PLA1A ADGRL2 FOXF1	4.44e-06	200	146	7	6a9b6a4b4f204598290ae21c87ddb42ac95dfc4c
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	NPR3 ITGA6 RALGAPA2 PLA1A ADGRF5 ADGRL2 FOXF1	4.44e-06	200	146	7	e9d5ba140cabae11c437012d519b85f5412dcc94
ToppCell	LPS_IL1RA_TNF-Endothelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SETX CD109 ITGA6 PPP3CA SLC12A2 ADGRF5 ADGRL2	4.44e-06	200	146	7	d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	NPR3 SETX CD109 ITGA6 PPP3CA ADGRF5 ADGRL2	4.44e-06	200	146	7	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 STXBP5L GLIS3 OR14I1 NWD2 ADGRF5 PDZD2	4.44e-06	200	146	7	96b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCell	Neuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 STXBP5L GLIS3 OR14I1 NWD2 ADGRF5 PDZD2	4.44e-06	200	146	7	ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCell	Biopsy_Control_(H.)-Endothelial-Endothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	NPR3 CD109 ITGA6 PTGDS PLA1A ADGRL2 FOXF1	4.44e-06	200	146	7	0242d465da2dfba0da629a43e152949c5192465b
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC7A13 EPHA6 STXBP5L LRP2 ELAVL4 TNR	6.63e-06	139	146	6	a1945b07f177cde40e7eea03a19236ce76165857
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TROAP CENPI MKI67 FOXF1 TBCD PDCD1LG2	1.28e-05	156	146	6	b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 SLC7A13 NEBL EPB41L4B POF1B HS2ST1	1.82e-05	166	146	6	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 SLC7A13 NEBL EPB41L4B POF1B HS2ST1	1.82e-05	166	146	6	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SDK2 STXBP5L LRP2 TRPM1 CTNND2 PDZD2	1.89e-05	167	146	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	Control\|World / group, cell type (main and fine annotations)	DLGAP1 NEBL LRP2 COBL ADGRF5 PDZD2	1.95e-05	168	146	6	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 EPPK1 NEBL AJAP1 ANO6 ATP1A2	2.09e-05	170	146	6	c638dfde9ce30190abbe0caea1c3eb874af09857
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 OR14I1 TGFBI NWD2 ADGRF5 PDZD2	2.38e-05	174	146	6	9cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP7A SLC35E1 DGKH LCP2 SLC12A2 PDZD2	2.46e-05	175	146	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMXL2 EPPK1 NEBL GLIS3 ANO6 ATP1A2	2.46e-05	175	146	6	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RB1 CD109 POF1B TULP2 ANO6 PLD1	2.54e-05	176	146	6	5e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATA7 DLGAP1 EPB41L4B DGKH THADA AJAP1	2.62e-05	177	146	6	291231b1520c135e92739e201495fe1935efa927
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	ATP7A MUC16 DGKD ZNF263 HS2ST1 CDYL2	2.79e-05	179	146	6	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	COVID-19-kidney-Stressed_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC CD109 AJAP1 ARHGEF7 ADGRF5 ADGRL2	2.79e-05	179	146	6	754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	SDK2 ESS2 IGSF10 PTPN12 KCNQ1 SLC24A1	2.79e-05	179	146	6	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	SECISBP2L DLGAP1 GLIS3 LAMP3 LRP2 ADGRF5	2.88e-05	180	146	6	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Endothelial-A-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	NPR3 PLA1A ADGRL2 TNR FOXF1 ZNF541	2.88e-05	180	146	6	4c3376169770ee9f9283daae44c17f35e46bfd19
ToppCell	COVID-19-Endothelial_cells-Capillary_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	AJAP1 SLC12A2 ADGRF5 ADGRL2 PLXNA2 FOXF1	2.97e-05	181	146	6	c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 GLIS3 NWD2 PPP3CA ADGRL2 PDZD2	2.97e-05	181	146	6	57994ff4ecffb15653aee00644d9f887f5e3461d
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	NEBL EPB41L4B RALGAPA2 KNDC1 COBL PDZD2	3.06e-05	182	146	6	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 ITGA6 ADGRF5 PLXNA2 TBCD	3.16e-05	183	146	6	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BOC CDK17 ITGA6 ADGRF5 PLXNA2 TBCD	3.16e-05	183	146	6	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	DLGAP1 NEBL LAMP3 LRP2 ADGRF5 PDZD2	3.25e-05	184	146	6	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	NEBL TGFB2 ANO6 COBL CTNND2 CPLANE1	3.35e-05	185	146	6	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	NPR3 CD109 ITGA6 NAV3 ADGRL2 FOXF1	3.35e-05	185	146	6	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC7A13 ITGA6 PKHD1 LRP2 COBL PDZD2	3.46e-05	186	146	6	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	EPB41L4B PKHD1 LAMP3 LRP2 ADGRF5 CTNND2	3.56e-05	187	146	6	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	NEBL SPHKAP ATP1A2 ADGRL2 RNF207 DYNC1I1	3.67e-05	188	146	6	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	NPR3 CD109 ITGA6 RALGAPA2 PLA1A ADGRL2	3.67e-05	188	146	6	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 PTGDS TGFB2 PKHD1 KCNQ1 PLD1	3.67e-05	188	146	6	842982de2197770f999a70083ed9fca40ac22d79
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPPK1 PTGDS TGFB2 PKHD1 KCNQ1 PLD1	3.67e-05	188	146	6	a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL GLIS3 RASGRP1 PKHD1 KCNQ1 SDK1	3.78e-05	189	146	6	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 NPR3 DGKH PKHD1 LRP2 SDK1	3.78e-05	189	146	6	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	CDK17 NPR3 RALGAPA2 PTPN12 ADGRF5 PLXNA2	3.78e-05	189	146	6	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EPHA6 TROAP MKI67 PKHD1 LRP2 CTNND2	3.78e-05	189	146	6	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CD109 DGKH SLC12A2 ADGRF5 CTNND2 ADGRL2	3.89e-05	190	146	6	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	human_hepatoblastoma-Endothelial_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BOC CD109 DGKH ADGRF5 ADGRL2 PDZD2	3.89e-05	190	146	6	8d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEBL GLIS3 RASGRP1 PKHD1 KCNQ1 SDK1	3.89e-05	190	146	6	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	COVID-19-Endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	NPR3 RALGAPA2 PLA1A ADGRF5 ADGRL2 PLXNA2	3.89e-05	190	146	6	9fbd92cd6d4683b2490504d29c43cf42020433d4
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; MCF7; HT_HG-U133A	STXBP5L ITGA6 TUBGCP2 AJAP1 ALMS1 CENPI LAMP3 NCR2 ARHGEF6	4.46e-06	193	146	9	4834_UP
Drug	Ondansetron Hydrochloride [103639-04-9]; Up 200; 12.2uM; PC3; HT_HG-U133A	NPR3 NEB PTGDS DNALI1 NFATC4 MTMR3 PLD1 NCR2 PLXNA2	5.27e-06	197	146	9	5796_UP
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; MCF7; HT_HG-U133A	DLGAP1 NPR3 HBP1 PTGDS LRP2 ADGRF5 ATP1A2 SLC24A1 VPS13B	5.96e-06	200	146	9	2265_UP
Disease	body weight	SECISBP2L CDK17 GAPVD1 NPR3 EPHA6 EPB41L4B DGKH SH2B1 TGFB2 SLC12A2 NFATC4 ARHGEF7 SPHKAP MTMR3 KCNQ1 ITIH6 MGA EIF2AK3 PDZD2 XPO7	2.50e-06	1261	141	20	EFO_0004338
Disease	creatinine measurement, glomerular filtration rate	THADA PTPN12 ALMS1 LRP2 KCNQ1 ADGRL2	2.17e-05	117	141	6	EFO_0004518, EFO_0005208
Disease	creatinine measurement	SPATA7 GAPVD1 SLC7A13 RDH14 GLIS3 DGKH NEB PTPN12 PPP3CA ALMS1 MTMR3 PKHD1 LRP2 KCNQ1 DLEC1 ADGRL2	2.32e-05	995	141	16	EFO_0004518
Disease	Cri-du-Chat Syndrome	TERT CTNND2	6.78e-05	3	141	2	C0010314
Disease	Gastrointestinal Stromal Sarcoma	BOC RB1 C2CD3 FOXF1	7.60e-05	47	141	4	C3179349
Disease	Gastrointestinal Stromal Tumors	BOC RB1 C2CD3 FOXF1	9.70e-05	50	141	4	C0238198
Disease	kidney disease (biomarker_via_orthology)	TGFBI PPP3CA MKI67	1.33e-04	21	141	3	DOID:557 (biomarker_via_orthology)
Disease	small cell carcinoma (is_implicated_in)	RB1 TERT	1.35e-04	4	141	2	DOID:0050685 (is_implicated_in)
Disease	Alzheimer disease, p-tau measurement	GLIS3 NCR2	1.35e-04	4	141	2	EFO_0004763, MONDO_0004975
Disease	Sensorineural Hearing Loss (disorder)	DMXL2 GLIS3 LRP2	1.76e-04	23	141	3	C0018784
Disease	cholangiocarcinoma (is_marker_for)	MUC16 PPP3CA MKI67 MUC6	2.54e-04	64	141	4	DOID:4947 (is_marker_for)
Disease	pancreatic ductal adenocarcinoma (is_marker_for)	CFHR3 TGFB2 PLD1	2.87e-04	27	141	3	DOID:3498 (is_marker_for)
Disease	macula measurement	ARHGEF7 MTMR3 LRP2 COBL TRPM1 CTNND2	3.06e-04	189	141	6	EFO_0008375
Disease	Progressive supranuclear palsy	SRSF2 EIF2AK3	3.36e-04	6	141	2	C0038868
Disease	Ophthalmoplegia, Progressive Supranuclear	SRSF2 EIF2AK3	3.36e-04	6	141	2	C4551862
Disease	Supranuclear Palsy, Progressive, 1	SRSF2 EIF2AK3	3.36e-04	6	141	2	C4551863
Disease	facial morphology measurement	DLGAP1 RDH14 GLIS3 THADA PTPN12 PKHD1 NAV3 CTNND2 VPS13B	4.21e-04	466	141	9	EFO_0007841
Disease	sensorineural hearing loss (biomarker_via_orthology)	PTGDS SLC12A2	6.23e-04	8	141	2	DOID:10003 (biomarker_via_orthology)
Disease	age at onset, coronary stenosis	DLEC1 PLD1	7.98e-04	9	141	2	EFO_0004847, MONDO_0006715
Disease	vital capacity	EPB41L4B RDH14 GLIS3 DCAF16 SH2B1 TGFB2 ZNF263 NFATC4 MTMR3 LRP2 ADGRL2 EIF2AK3 ARHGEF6 DYNC1I1 PDZD2	8.68e-04	1236	141	15	EFO_0004312
Disease	multisite chronic pain	BBX KNDC1 SDK1 DYNC1I1	1.14e-03	95	141	4	EFO_0010100
Disease	ejection fraction measurement	DLGAP1 DGKH PPP3CA	1.15e-03	43	141	3	EFO_0005527
Disease	neutropenia, response to gemcitabine	TGFB2 DLEC1	1.21e-03	11	141	2	GO_0036272, MONDO_0001475
Disease	smoking behavior	GAPVD1 BBX PKHD1 NAV3 ELAVL4 SDK1 PLXNA2	1.31e-03	341	141	7	EFO_0004318
Disease	hydroxy-leucine measurement	DGKH ALMS1 ADGRL2	1.31e-03	45	141	3	EFO_0005276
Disease	spontaneous preterm birth	DLGAP1 DLEC1 SDK1 TBCD	1.42e-03	101	141	4	EFO_0006917
Disease	Night blindness, congenital stationary, type 1	TRPM1 SLC24A1	1.45e-03	12	141	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	TRPM1 SLC24A1	1.45e-03	12	141	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	TRPM1 SLC24A1	1.45e-03	12	141	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	TRPM1 SLC24A1	1.45e-03	12	141	2	C1850362
Disease	X-Linked Csnb	TRPM1 SLC24A1	1.45e-03	12	141	2	C3711543
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	TRPM1 SLC24A1	1.45e-03	12	141	2	C1848172
Disease	tonsillectomy risk measurement	VPS50 GLIS3 ITGA6 SH2B1 AJAP1 MTMR3	1.61e-03	260	141	6	EFO_0007924
Disease	amyloid-beta measurement	BOC KREMEN1 THADA SPHKAP CTNND2 SDK1 PDZD2	1.64e-03	355	141	7	EFO_0005194
Disease	Hepatic fibrosis	SDK2 TNR SDK1	1.68e-03	49	141	3	HP_0001395
Disease	susceptibility to measles measurement	NEBL BBX CTNND2	1.68e-03	49	141	3	EFO_0008414
Disease	Cone-rod synaptic disorder, congenital nonprogressive	TRPM1 SLC24A1	1.71e-03	13	141	2	C4041558
Disease	T wave morphology measurement	KCNQ1 RNF207	1.99e-03	14	141	2	EFO_0008398
Disease	waist-hip ratio	DMXL2 NPR3 EPB41L4B DGKQ LCP2 SH2B1 THADA BBX NAV3 CDYL2 ADGRF5 DLEC1 OLFM2 PLD1	2.27e-03	1226	141	14	EFO_0004343
Disease	Cleft palate, cleft lip	THADA MTMR3 PKHD1 DLEC1 SDK1 VPS13B	2.29e-03	279	141	6	EFO_0003959, HP_0000175
Disease	Varicose veins	ITGA6 TGFB2 SLC12A2 RP1L1 ADGRF5	2.40e-03	193	141	5	HP_0002619
Disease	Tremor, Rubral	ABCB7 ATP7A	2.60e-03	16	141	2	C0750940
Disease	Ataxia, Appendicular	ABCB7 ATP7A	2.60e-03	16	141	2	C0750937
Disease	Ataxia, Motor	ABCB7 ATP7A	2.60e-03	16	141	2	C0278161
Disease	coronary thrombosis, GM11992	EPB41L4B NCR2	2.60e-03	16	141	2	EFO_0001124, EFO_1000883
Disease	Ataxia, Sensory	ABCB7 ATP7A	2.60e-03	16	141	2	C0240991
Disease	Abnormal coordination	ABCB7 ATP7A	2.60e-03	16	141	2	C0520966
Disease	Ataxia, Truncal	ABCB7 ATP7A	2.60e-03	16	141	2	C0427190
Disease	Night blindness, congenital stationary	TRPM1 SLC24A1	2.94e-03	17	141	2	C0339535
Disease	response to opioid	DLGAP1 MUC16 TNR	3.14e-03	61	141	3	EFO_0008541
Disease	Adrenocortical carcinoma	RB1 TERT	3.30e-03	18	141	2	C0206686
Disease	urolithiasis	DGKD DGKH VPS13B	3.44e-03	63	141	3	MONDO_0024647
Disease	Disorder of eye	SPATA7 ALMS1 TRPM1 CPLANE1 SLC24A1	3.58e-03	212	141	5	C0015397
Disease	hemoglobin A1 measurement	DGKD RASGRP1 THADA RP1L1 MTMR3 KCNQ1 PLD1 MGA	3.62e-03	520	141	8	EFO_0007629
Disease	telomere length	CDK15 TERT MROH8 NCR2 CPLANE1 TNR	4.03e-03	313	141	6	EFO_0004505
Disease	eye colour measurement	GAPVD1 SAXO1 NWD2 PPP3CA LRP2	4.03e-03	218	141	5	EFO_0009764
Disease	cerebellum white matter volume change measurement, age at assessment	DGKH FOXF1	4.07e-03	20	141	2	EFO_0008007, EFO_0021498
Disease	polymyositis	SDK2 DGKQ	4.07e-03	20	141	2	EFO_0003063
Disease	Microcephaly	TMX2 ATP1A2 TBCD	4.09e-03	67	141	3	C0025958
Disease	Sarcoma	RB1 CIC	4.49e-03	21	141	2	C1261473
Disease	in situ carcinoma (is_marker_for)	RB1 MKI67	4.49e-03	21	141	2	DOID:8719 (is_marker_for)
Disease	nose morphology measurement, mouth morphology measurement	SPATA7 KCNQ1	4.49e-03	21	141	2	EFO_0007843, EFO_0007955
Disease	disease	RASGRP1 DYNC1I1	4.49e-03	21	141	2	EFO_0000408

Protein segments in the cluster

Peptide	Gene	Start	Entry
TTTQLYTDRTEKLRP	TGFBI	116	Q15582
RKFYTNSRTTIESPS	C2orf16	1301	Q68DN1
SSSAYIAVPTLQTDR	nan	71	Q9N2J8
SNYVREIKSSERPLS	ARHGEF6	211	Q15052
YSASSKIIISDVPSR	BBX	411	Q8WY36
YLQSSVRISEKFPSS	EIF2AK3	396	Q9NZJ5
SVASSRPQEVSAYLT	ARMC6	101	Q6NXE6
LTSKLVLVSPTSEQY	GTPBP1	61	O00178
VLSSPRKTAQDTLYV	RASGRP1	691	O95267
SVSSSLYSYREKPIV	ALMS1	1706	Q8TCU4
VTSTSYSHREKPIVS	ALMS1	1801	Q8TCU4
YGPTTVSILQTRKTT	AJAP1	201	Q9UKB5
AYVSVRVTPKSTARS	DGKQ	411	P52824
VSINKESSRVYLTDP	ADGRL2	756	O95490
ARRESYLKATQPSLT	DLGAP1	371	O14490
TIKVSYARPSSASIR	ELAVL4	121	P26378
TYLRPLQTSEKLSSA	ARHGEF7	296	Q14155
TSYRISEESTKIPQS	DMXL2	1441	Q8TDJ6
SYVQLTSRALPSLTD	HSD11B1L	141	Q7Z5J1
RLAKSYSTSSPINIV	CTNND2	306	Q9UQB3
VKETTRTEPINTTYS	DCAF16	186	Q9NXF7
YSSLQTVTLLRTVKP	NPR3	316	P17342
YNASSVTPESLRKAI	ATP7A	321	Q04656
VSYSSDLPATSVIIT	GALNT16	116	Q8N428
IPTIVASSNLRVYTS	NWD2	306	Q9ULI1
LIYLTQPSSSISTEI	RB1	171	P06400
PLSSVLEQYKADTRT	OLFM2	131	O95897
LYSSKDTTKRPVTTT	PDCD1LG2	251	Q9BQ51
YTSDKSTTPASNIVR	GDF2	96	Q9UK05
YLTPQTATSITASII	ANO6	501	Q4KMQ2
YITSTAQTTSLVSLP	MUC16	3451	Q8WXI7
TPLATTQRFTYSEKT	MUC16	4121	Q8WXI7
PYKELTGATTEVSRT	MUC16	4916	Q8WXI7
PYKTRNITVFRQTST	MUC6	481	Q6W4X9
YSSAVAPKTVAALRS	OR5B21	71	A6NL26
YDSSVRKSPTLLEVS	KCNQ1	461	P51787
TVREAPQIYSLSSSS	KCTD21	126	Q4G0X4
KSVRFYLVVSPASAS	NCR2	121	O95944
PRTTVKDSDITATYK	SLC24A1	216	O60721
QLPTKSTSYVRTLDS	MGA	856	Q8IWI9
RPNLLITESTYATTI	INTS11	196	Q5TA45
SESTITISLYIPSEQ	HEBP2	101	Q9Y5Z4
TKSYPVTRSEATAAT	KIAA2026	1446	Q5HYC2
SAQSEIRTISAYKTP	GAPVD1	1376	Q14C86
TSPNYRLIKSRSESD	HERC1	1501	Q15751
REVVSYSKETQTPLA	DYNC1I1	161	O14576
ENPTSIKLTTTYTRR	HMGXB3	296	Q12766
KRFSVYVTESQPDLS	EIF2B1	146	Q14232
DRSVVALVPKQTSSY	PLXNA2	1591	O75051
KLEYTVRTDTQSPTN	PDZD2	1086	O15018
SSVSSYSNITVPSRK	NAV3	906	Q8IVL0
ARSSKVLYVITTSPS	KREMEN1	351	Q96MU8
TKNTATTSPITYTLV	LAMP3	91	Q9UQV4
LLQKNRTPYVTTTVS	TUBGCP2	31	Q9BSJ2
YSTNPRTQSIEVLTL	LRP2	1836	P98164
RAKSVPTKTYSNEVV	CDK17	336	Q00537
VRVTVFPSKTVAQYS	ITGA6	1036	P23229
KTTKVSYRASQPDLV	MKI67	1731	P46013
SSLKSVQTREPYEVA	DGKH	151	Q86XP1
INTVSLFISRPKYTD	MROH8	406	Q9H579
TTTRDNENIYSTKIP	RALGAPA2	281	Q2PPJ7
SREVLSPLKTTSSYQ	POF1B	71	Q8WVV4
SPSTARSRITKYSTV	DSG1	1031	Q02413
STYYNPSLKSRVTIS	IGHV4-38-2	76	P0DP08
KSTSKTYVISRTEPA	RBBP6	81	Q7Z6E9
ISYTNVFSTILKIPS	OR1G1	216	P47890
PALQRLVSRTASKYT	ESS2	396	Q96DF8
KSIAYTLTSNIPEIT	ATP1A2	771	P50993
YTTVLKPSLNFTATV	CD109	356	Q6YHK3
TTSFLLKVYVPQSRV	CFHR3	221	Q02985
TVVRKVDATDASYPS	HECTD1	2561	Q9ULT8
KTTPTIKYFRTEISQ	IGSF10	1121	Q6WRI0
SSSQTIYPGIKARIT	BPIFC	21	Q8NFQ6
IILSSPRTSKTDSYE	BOC	476	Q9BWV1
LQTEPKAVRTTTRYA	C2CD3	81	Q4AC94
ARAKSIPSQTYSSEV	CDK15	246	Q96Q40
ESSSEYSPVIRVKTS	CPLANE1	1766	Q9H799
FNTIIRTSPTSLVAY	GLIS3	161	Q8NEA6
TTEVTFLKPQRRTSS	COBL	851	O75128
YDTPVLVSRNTEKRS	DNALI1	11	O14645
TVTTDKPRAYTITIS	ITIH6	1146	Q6UXX5
YEAKLPRQASSSTVT	DGKD	451	Q16760
YNRSSPVHIIATSKS	HBP1	131	O60381
QDPTSTFTKIYRRSL	KNDC1	1306	Q76NI1
SLSVIPVLNSSSYTK	CENPI	306	Q92674
PISSLRTTSYTIDQA	DLEC1	1241	Q9Y238
VKDIPRSATSYTLSL	SDK1	1951	Q7Z5N4
TSTYLAVTSIAPNIT	SDK2	391	Q58EX2
STPEVQSEQSSVRYK	SPACA1	256	Q9HBV2
STVQTIYTTRKPVSL	EPB41L4B	861	Q9H329
IYTTRKPVSLAASAE	EPB41L4B	866	Q9H329
YRKSQTTGFPSLITI	PPP3CA	291	Q08209
QFPSTVSTVYRTSEK	CTU2	356	Q2VPK5
SRLPKTRSYDNLTTA	MTMR3	606	Q13615
SYARIVSSILKVPSS	OR1E2	226	P47887
QLTLSYSKTVSEDRP	nan	106	A6NNC1
TEKTTTYQYPRAILS	PHF20L1	616	A8MW92
EQLTYSSTRSKAPSV	EPHA6	486	Q9UF33
QPLSSYTVKDRIATI	OR1L3	261	Q8NH93
YISVTVPKSIRNSLT	OR14I1	71	A6ND48
IQSSPTKRLTLSEIY	FOXF1	61	Q12946
VTTYTSEASKPRAQA	RTP2	176	Q5QGT7
SQKVFSPQTRTVDLY	TAAR5	321	O14804
YLTTITKQITPYVRS	RNF207	526	Q6ZRF8
SSDVVLVSYVPSSQR	SH2B1	616	Q9NRF2
KEAALVLTRPNTYSS	SPHKAP	621	Q2M3C7
LKVDNLTYRTSPDTL	SRSF2	16	Q01130
SYRLSTVVSPVIQSS	THADA	956	Q6YHU6
EIPFESLTTQKQSYR	SAXO1	231	Q8IYX7
SLNLSPARYVTVKTI	TADA2B	361	Q86TJ2
ISLKTTSDLVSRNYP	BMT2	321	Q1RMZ1
LTLTVPEYSNKRVSR	NFATC4	646	Q14934
FTSTTRVPSINLYTI	PLD1	91	Q13393
PFIKYSTRQALSTAT	EPPK1	481	P58107
IIYNRVPKTASTSFT	HS2ST1	76	Q7LGA3
ATLYSRTQTPRAELK	PTGDS	146	P41222
SDINYQTRKTVSLTP	PTPN12	556	Q05209
IRNSSVRTKLEPESY	SETX	331	Q7Z333
ITNTRPLSYTVVTAA	SECISBP2L	511	Q93073
TYVSSLNPVIVTLSR	PKHD1	1101	P08F94
KTTTVNYVRDTLSNP	PKHD1	2596	P08F94
SSAPSRIVVVSSKLY	RDH14	181	Q9HBH5
VSPLSYSVANATKRI	SLC35E1	286	Q96K37
PDLTKRIRTSYQSLT	STXBP5L	716	Q9Y2K9
TARAYQIPESLKSIT	ABCB7	51	O75027
ARTLYKSTLNIPTEE	BRS3	241	P32247
RAVATKSPTAEEYTV	ADGRF5	51	Q8IZF2
ATKTVSYRTTPSGLQ	CDYL2	131	Q8N8U2
VLLPSSTRITYVQSA	CIC	996	Q96RK0
DLTSPTQRYIDSKVV	TGFB2	176	P61812
ITSSSKITIPKQQRY	PLA1A	366	Q53H76
YSQTVSTASELRKPI	VPS50	766	Q96JG6
DVSTRYKVSTSPLTK	TMX2	201	Q9Y320
YPASSLVVVRSKTED	TMEM59	291	Q9BXS4
ARALPIYTTSASKTI	ZDHHC20	111	Q5W0Z9
RRSKTSNYLISLDPT	TULP2	326	O00295
SNLSTEDYIKRVPSI	THOC2	786	Q8NI27
SDLLRFPVKQLYTTS	RP1L1	186	Q8IWN7
TPTRDAVVTYTAESK	SLC12A2	266	P55011
IASEVTVPKDRTSYT	TNR	726	Q92752
TSYSVLRRLTVQPKT	TROAP	341	Q12815
PVSVSTSIKYADQQR	SPATA7	71	Q9P0W8
SIFKSSRPIYLASQE	SLC7A13	306	Q8TCU3
KITRSHSTDIPYIVS	TRPM1	1476	Q7Z4N2
AVTLIKYVAPESTSS	ZBED5	356	Q49AG3
PTVATSVQSPYRSTK	USP24	906	Q9UPU5
YASSPVKTKTVTESR	VPS13B	1016	Q7Z7G8
TPEVTKAYITSRLES	XPO7	406	Q9UIA9
FPLIRKTTASQVYET	TBCD	1121	Q9BTW9
TRKSVPRNSLESAEY	TOGARAM1	1476	Q9Y4F4
TTSVRSYLPNTVTDA	TERT	116	O14746
AITRPTAVNSLISKY	UFL1	196	O94874
KAVFVPDIYSRTQST	UFL1	241	O94874
TKSYRRESILSSSPN	ZNF541	1256	Q9H0D2
PSKRALSRDTVQESY	ZNF263	236	O14978
LVRDSSKKTTTNPYV	LCP2	446	Q13094
YSTIADTPEIQRIKT	NEBL	571	O76041
RTPVVNLKYTSIVDT	NEB	3906	P20929