Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH5 DNAH9 DNAH11

3.02e-0718654GO:0008569
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 NLRP10 MDN1 MACF1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

1.51e-064416510GO:0016887
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH17 DNAH5 DNAH9 DNAH11

1.97e-0628654GO:0051959
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC9 ABCC2

3.89e-0610653GO:0043225
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 NLRP10 MDN1 DNAH17 MACF1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

4.21e-066146511GO:0140657
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DNAH5 DNAH9 DNAH11

6.23e-0637654GO:0045505
GeneOntologyMolecularFunctionpyrophosphatase activity

ABCC3 NLRP10 MDN1 ASMTL DNM3 MACF1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

1.45e-058396512GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ABCC3 NLRP10 MDN1 ASMTL DNM3 MACF1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

1.46e-058406512GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ABCC3 NLRP10 MDN1 ASMTL DNM3 MACF1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

1.46e-058406512GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

ABCC3 NLRP10 MDN1 DNM3 MACF1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

3.70e-057756511GO:0017111
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH17 DNAH5 DNAH9 DNAH11

7.98e-0570654GO:0003777
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC2

2.88e-048652GO:0015431
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCC9 ABCC2

5.45e-0449653GO:0140359
GeneOntologyMolecularFunctionstructural molecule activity

KRT15 ANK2 DNM3 LAMA2 MACF1 PSMD11 DMD NEB RIMS2 PPL

5.73e-048916510GO:0005198
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH17 DNAH5 DNAH9 DNAH11

5.94e-04118654GO:0003774
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

KRT15 ANK2 DMD PPL

8.54e-04130654GO:0005200
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC2

1.07e-0315652GO:0008559
GeneOntologyMolecularFunctionlamin binding

SYNE1 DMD

1.72e-0319652GO:0005521
GeneOntologyMolecularFunctionnitric-oxide synthase binding

DNM3 DMD

2.31e-0322652GO:0050998
GeneOntologyBiologicalProcesscilium movement

MEIG1 DNAH17 VPS13A DNAH5 DNAH9 HYDIN DNAH11

1.98e-05261667GO:0003341
GeneOntologyBiologicalProcessregulation of SA node cell action potential

ANK2 RYR2

3.02e-053662GO:0098907
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion

ANK2 DMD RYR2

4.61e-0522663GO:0010881
GeneOntologyBiologicalProcesscilium movement involved in cell motility

MEIG1 DNAH17 VPS13A DNAH5 DNAH9 DNAH11

5.67e-05210666GO:0060294
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell action potential

ANK2 RYR2

6.03e-054662GO:0098910
GeneOntologyBiologicalProcesscilium-dependent cell motility

MEIG1 DNAH17 VPS13A DNAH5 DNAH9 DNAH11

6.45e-05215666GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

MEIG1 DNAH17 VPS13A DNAH5 DNAH9 DNAH11

6.45e-05215666GO:0001539
GeneOntologyBiologicalProcessregulation of cardiac muscle contraction by calcium ion signaling

ANK2 DMD RYR2

9.68e-0528663GO:0010882
GeneOntologyBiologicalProcessregulation of AV node cell action potential

ANK2 RYR2

1.00e-045662GO:0098904
GeneOntologyBiologicalProcesssomatic muscle development

PPP2R3A NEB

1.50e-046662GO:0007525
GeneOntologyBiologicalProcesscanalicular bile acid transport

ABCC3 ABCC2

1.50e-046662GO:0015722
GeneOntologyBiologicalProcessregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

ANK2 DMD RYR2

1.59e-0433663GO:0010880
GeneOntologyBiologicalProcessmicrotubule-based movement

MREG MEIG1 DNAH17 VPS13A DNAH5 DNAH9 HYDIN DNAH11

1.71e-04493668GO:0007018
GeneOntologyBiologicalProcesscardiac muscle contraction

ANK2 MTOR ABCC9 DMD RYR2

1.97e-04167665GO:0060048
GeneOntologyBiologicalProcessleukotriene transport

ABCC3 ABCC2

2.10e-047662GO:0071716
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

ANK2 DMD RYR2

2.25e-0437663GO:0014808
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

ANK2 DMD RYR2

2.63e-0439663GO:1903514
GeneOntologyBiologicalProcessmaintenance of blood-brain barrier

LAMA2 DMD OCLN

3.29e-0442663GO:0035633
GeneOntologyBiologicalProcessnucleus localization

MTOR SYNE1 DMD

3.77e-0444663GO:0051647
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

ANK2 DMD RYR2

3.77e-0444663GO:0070296
GeneOntologyBiologicalProcessaxoneme assembly

MEIG1 DNAH17 DNAH5 HYDIN

4.13e-04109664GO:0035082
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

ANK2 RYR2

4.46e-0410662GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

ANK2 RYR2

4.46e-0410662GO:0086015
GeneOntologyBiologicalProcessaction potential

ANK2 MTOR ABCC9 DMD RYR2

4.61e-04201665GO:0001508
GeneOntologyBiologicalProcessmicrotubule-based process

MREG MEIG1 DNAH17 VPS13A MACF1 OCLN DNAH5 GBA2 DNAH9 HYDIN DNAH11

4.92e-0410586611GO:0007017
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

ANK2 RYR2

5.44e-0411662GO:0086070
GeneOntologyBiologicalProcesspostsynaptic endocytosis

SYNE1 IQSEC1 DNM3

5.84e-0451663GO:0140239
GeneOntologyBiologicalProcesspostsynaptic neurotransmitter receptor internalization

SYNE1 IQSEC1 DNM3

5.84e-0451663GO:0098884
GeneOntologyBiologicalProcessactin filament-based process

FAT1 ANK2 MTOR ARHGAP12 IQSEC1 ABCC9 NEB TRIM27 GBA2 RYR2

6.05e-049126610GO:0030029
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

ANK2 RYR2

6.52e-0412662GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

ANK2 RYR2

6.52e-0412662GO:0086016
GeneOntologyBiologicalProcessstriated muscle contraction

ANK2 MTOR ABCC9 DMD RYR2

6.53e-04217665GO:0006941
GeneOntologyBiologicalProcesspositive regulation of keratinocyte migration

MTOR IQSEC1

7.69e-0413662GO:0051549
GeneOntologyCellularComponentsupramolecular fiber

KRT15 ANK2 SYNE1 DNAH17 DNM3 FAM161B MACF1 ABCC9 DMD NEB DNAH5 DNAH9 PPL RYR2 DNAH11

3.68e-0611796715GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KRT15 ANK2 SYNE1 DNAH17 DNM3 FAM161B MACF1 ABCC9 DMD NEB DNAH5 DNAH9 PPL RYR2 DNAH11

4.00e-0611876715GO:0099081
GeneOntologyCellularComponentouter dynein arm

DNAH17 DNAH5 DNAH9

6.78e-0612673GO:0036157
GeneOntologyCellularComponentdynein complex

DNAH17 DNAH5 DNAH9 DNAH11

2.70e-0554674GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH17 DNAH5 DNAH9

6.88e-0525673GO:0005858
GeneOntologyCellularComponent9+2 motile cilium

MROH2B DNAH17 VPS13A DNAH5 DNAH9 DNAH11

1.14e-04238676GO:0097729
GeneOntologyCellularComponentmotile cilium

MROH2B DNAH17 STARD10 VPS13A DNAH5 DNAH9 DNAH11

1.39e-04355677GO:0031514
GeneOntologyCellularComponentsarcomere

ANK2 SYNE1 ABCC9 DMD NEB RYR2

1.46e-04249676GO:0030017
GeneOntologyCellularComponent9+0 motile cilium

DNAH5 DNAH11

1.51e-046672GO:0097728
GeneOntologyCellularComponentmyofibril

ANK2 SYNE1 ABCC9 DMD NEB RYR2

2.40e-04273676GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

ANK2 SYNE1 ABCC9 DMD NEB RYR2

3.32e-04290676GO:0043292
GeneOntologyCellularComponentintercellular canaliculus

STARD10 ABCC2

3.59e-049672GO:0046581
GeneOntologyCellularComponentsarcolemma

ANK2 LAMA2 ABCC9 DMD RYR2

3.60e-04190675GO:0042383
GeneOntologyCellularComponentaxoneme

DNAH17 DNAH5 DNAH9 HYDIN DNAH11

5.32e-04207675GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH17 DNAH5 DNAH9 HYDIN DNAH11

5.44e-04208675GO:0097014
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KRT15 DNAH17 DNM3 FAM161B MACF1 DMD DNAH5 DNAH9 PPL DNAH11

5.52e-048996710GO:0099513
GeneOntologyCellularComponentlamellipodium

FAT1 P4HB ANGPTL3 NHS DMD

8.56e-04230675GO:0030027
GeneOntologyCellularComponentapical plasma membrane

MREG FAT1 ANK2 NHS AKR1A1 ABCC2 OCLN

9.29e-04487677GO:0016324
GeneOntologyCellularComponentcytoplasmic region

DNAH17 RIMS2 DNAH5 DNAH9 HYDIN DNAH11

1.03e-03360676GO:0099568
GeneOntologyCellularComponentcell leading edge

FAT1 P4HB ANGPTL3 NHS MACF1 DMD OCLN

1.08e-03500677GO:0031252
GeneOntologyCellularComponentdendritic spine head

SYNE1 DNM3

1.18e-0316672GO:0044327
GeneOntologyCellularComponentZ disc

ANK2 DMD NEB RYR2

1.41e-03151674GO:0030018
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT15 MDN1 MACF1 DMD PPL

1.55e-03263675GO:0045111
GeneOntologyCellularComponentmicrotubule

DNAH17 DNM3 FAM161B MACF1 DNAH5 DNAH9 DNAH11

1.56e-03533677GO:0005874
GeneOntologyCellularComponentmicrotubule associated complex

DNAH17 DNAH5 DNAH9 DNAH11

1.78e-03161674GO:0005875
GeneOntologyCellularComponentI band

ANK2 DMD NEB RYR2

1.99e-03166674GO:0031674
GeneOntologyCellularComponentnuclear envelope

NLRP10 MTOR POLA1 SYNE1 AGPAT3 TRIM27 RYR2

2.07e-03560677GO:0005635
GeneOntologyCellularComponentcilium

MROH2B DNAH17 STARD10 VPS13A FAM161B DNAH5 DNAH9 HYDIN DNAH11

2.19e-03898679GO:0005929
GeneOntologyCellularComponentcostamere

ANK2 DMD

2.24e-0322672GO:0043034
GeneOntologyCellularComponentcell-cell junction

FAT1 ANK2 STARD10 NHS ABCC2 OCLN PPL

2.79e-03591677GO:0005911
GeneOntologyCellularComponentapical part of cell

MREG FAT1 ANK2 NHS AKR1A1 ABCC2 OCLN

2.82e-03592677GO:0045177
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH17 DNAH5 DNAH9 HYDIN DNAH11

3.48e-03317675GO:0032838
GeneOntologyCellularComponentanchoring junction

FAT1 ANK2 P4HB STARD10 NHS DMD ABCC2 OCLN PPL

3.81e-03976679GO:0070161
GeneOntologyCellularComponentsynaptic cleft

DNM3 LAMA2

5.01e-0333672GO:0043083
GeneOntologyCellularComponentmelanosome

MREG P4HB CALU

5.73e-03113673GO:0042470
GeneOntologyCellularComponentpigment granule

MREG P4HB CALU

5.73e-03113673GO:0048770
GeneOntologyCellularComponentintermediate filament

KRT15 MACF1 DMD PPL

6.08e-03227674GO:0005882
HumanPhenoAbnormal sperm motility

DNAH17 DNAH5 GBA2 DNAH9 HYDIN DNAH11

5.39e-05115316HP:0012206
HumanPhenoAbnormal sperm physiology

DNAH17 DNAH5 GBA2 DNAH9 HYDIN DNAH11

5.39e-05115316HP:0034809
HumanPhenoAbnormal respiratory motile cilium physiology

DNAH5 DNAH9 HYDIN DNAH11

5.77e-0536314HP:0012261
HumanPhenoAtelectasis

LAMA2 DNAH5 DNAH9 HYDIN DNAH11

1.04e-0480315HP:0100750
HumanPhenoSquare-wave jerks

SYNE1 VPS13A

1.07e-043312HP:0025402
HumanPhenoSaccadic intrusion

SYNE1 VPS13A

1.07e-043312HP:0032114
HumanPhenoPosterior Y-sutural cataract

NHS SEC23A

1.07e-043312HP:0008031
HumanPhenoPeribronchovascular interstitial thickening

DNAH5 DNAH9 HYDIN DNAH11

1.96e-0449314HP:0025177
HumanPhenoEctopic pregnancy

DNAH5 DNAH9 HYDIN DNAH11

1.96e-0449314HP:0031456
HumanPhenoPulmonary situs ambiguus

DNAH5 DNAH9 HYDIN DNAH11

1.96e-0449314HP:0011617
HumanPhenoAbnormal pulmonary situs morphology

DNAH5 DNAH9 HYDIN DNAH11

1.96e-0449314HP:0011615
HumanPhenoLithoptysis

DNAH5 DNAH9 HYDIN DNAH11

1.96e-0449314HP:0032543
HumanPhenoAtrial situs ambiguous

DNAH5 DNAH9 HYDIN DNAH11

2.13e-0450314HP:0011539
HumanPhenoAbnormal inferior vena cava morphology

DNAH5 DNAH9 HYDIN DNAH11

2.67e-0453314HP:0025576
HumanPhenoAbnormal atrial arrangement

DNAH5 DNAH9 HYDIN DNAH11

2.87e-0454314HP:0011535
MousePhenobiventricular, ambiguous atrioventricular connection

DNAH5 DNAH11

1.69e-052582MP:0011511
MousePhenobiventricular, discordant atrioventricular connection

DNAH5 DNAH11

5.06e-053582MP:0011510
DomainAAA+_ATPase

ABCC3 MDN1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

3.16e-08144648IPR003593
DomainAAA

ABCC3 MDN1 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 DNAH11

3.16e-08144648SM00382
DomainATPase_dyneun-rel_AAA

MDN1 DNAH5 DNAH9 DNAH11

1.22e-0714644IPR011704
DomainAAA_5

MDN1 DNAH5 DNAH9 DNAH11

1.22e-0714644PF07728
DomainDHC_N1

DNAH5 DNAH9 DNAH11

2.12e-068643PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH9 DNAH11

2.12e-068643IPR013594
DomainSpectrin_repeat

SYNE1 MACF1 DMD PPL

2.79e-0629644IPR002017
DomainSpectrin/alpha-actinin

SYNE1 MACF1 DMD PPL

4.19e-0632644IPR018159
DomainSPEC

SYNE1 MACF1 DMD PPL

4.19e-0632644SM00150
DomainDynein_heavy_chain_D4_dom

DNAH5 DNAH9 DNAH11

1.36e-0514643IPR024317
DomainDynein_HC_stalk

DNAH5 DNAH9 DNAH11

1.36e-0514643IPR024743
DomainDynein_heavy_dom-2

DNAH5 DNAH9 DNAH11

1.36e-0514643IPR013602
DomainDHC_N2

DNAH5 DNAH9 DNAH11

1.36e-0514643PF08393
DomainMT

DNAH5 DNAH9 DNAH11

1.36e-0514643PF12777
DomainAAA_8

DNAH5 DNAH9 DNAH11

1.36e-0514643PF12780
DomainDHC_fam

DNAH5 DNAH9 DNAH11

1.70e-0515643IPR026983
DomainDynein_heavy_dom

DNAH5 DNAH9 DNAH11

1.70e-0515643IPR004273
DomainDynein_heavy

DNAH5 DNAH9 DNAH11

1.70e-0515643PF03028
Domain-

ABCC3 NLRP10 MDN1 DNM3 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 HYDIN DNAH11

4.12e-0574664113.40.50.300
DomainActinin_actin-bd_CS

SYNE1 MACF1 DMD

6.47e-0523643IPR001589
DomainSpectrin

SYNE1 MACF1 DMD

6.47e-0523643PF00435
DomainACTININ_2

SYNE1 MACF1 DMD

6.47e-0523643PS00020
DomainACTININ_1

SYNE1 MACF1 DMD

6.47e-0523643PS00019
DomainMultidrug-R_assoc

ABCC3 ABCC2

6.90e-054642IPR005292
DomainABC_membrane

ABCC3 ABCC9 ABCC2

7.38e-0524643PF00664
DomainABC_TM1F

ABCC3 ABCC9 ABCC2

1.18e-0428643PS50929
DomainABC1_TM_dom

ABCC3 ABCC9 ABCC2

1.18e-0428643IPR011527
DomainP-loop_NTPase

ABCC3 NLRP10 MDN1 DNM3 ABCC9 ABCC2 ASCC3 DNAH5 DNAH9 HYDIN DNAH11

1.30e-048486411IPR027417
DomainPlectin_repeat

MACF1 PPL

2.40e-047642IPR001101
DomainPlectin

MACF1 PPL

2.40e-047642PF00681
DomainPLEC

MACF1 PPL

2.40e-047642SM00250
DomainABC_transporter_CS

ABCC3 ABCC9 ABCC2

4.00e-0442643IPR017871
DomainABC_tran

ABCC3 ABCC9 ABCC2

5.95e-0448643PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCC9 ABCC2

5.95e-0448643PS50893
DomainABC_TRANSPORTER_1

ABCC3 ABCC9 ABCC2

6.32e-0449643PS00211
DomainABC_transporter-like

ABCC3 ABCC9 ABCC2

6.70e-0450643IPR003439
DomainCH

SYNE1 MACF1 DMD

1.44e-0365643SM00033
DomainCH

SYNE1 MACF1 DMD

1.78e-0370643PF00307
DomainHEAT_REPEAT

MTOR MROH2A MROH2B

1.78e-0370643PS50077
DomainEF-hand_1

PPP2R3A CALU MACF1 RYR2

1.83e-03152644PF00036
Domain-

SYNE1 MACF1 DMD

1.86e-03716431.10.418.10
Domain-

PPP2R3A CALU MACF1 DMD RYR2

2.00e-032616451.10.238.10
DomainCH

SYNE1 MACF1 DMD

2.01e-0373643PS50021
DomainCH-domain

SYNE1 MACF1 DMD

2.17e-0375643IPR001715
DomainEF-hand-dom_pair

PPP2R3A CALU MACF1 DMD RYR2

3.01e-03287645IPR011992
DomainEF-hand_8

CALU RYR2

6.04e-0334642PF13833
DomainConA-like_dom

FAT1 LAMA2 TRIM27 RYR2

6.75e-03219644IPR013320
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH17 DNAH5 DNAH9 DNAH11

2.51e-0627514M47755
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH17 DNAH5 DNAH9 DNAH11

1.69e-0543514M47669
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH17 DNAH5 DNAH9 DNAH11

2.03e-0545514M47670
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH5 DNAH9 DNAH11

4.38e-10767431178125
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MDN1 FAM186A SYNE1 KRI1 MACF1 DMD NEB TRIM27 DNAH5

7.38e-1023467936243803
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KRT15 MDN1 ANK2 P4HB FAM186A SYNE1 ARHGAP12 STARD10 VPS13A MACF1 DMD ABCC2 NEB RIMS2 UBLCP1 PPL RYR2

1.36e-091442671735575683
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

DNAH9 HYDIN DNAH11

2.73e-08467336140829
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCC3 LAMA2 ABCC9 DMD ABCC2 OCLN

5.63e-0810567630280653
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH9 DNAH11

6.81e-08567326909801
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

DNAH5 DNAH9 DNAH11

1.36e-07667333347437
Pubmed

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.

LAMA2 DMD RYR2

8.12e-071067318434328
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH17 DNAH5 DNAH11

2.45e-06146739373155
Pubmed

Crosstalk between RyR2 oxidation and phosphorylation contributes to cardiac dysfunction in mice with Duchenne muscular dystrophy.

DMD RYR2

3.66e-06267226555638
Pubmed

Extended tropism of an adenoviral vector does not circumvent the maturation-dependent transducibility of mouse skeletal muscle.

LAMA2 DMD

3.66e-06267210753064
Pubmed

Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.

ABCC3 ABCC2

3.66e-06267212704183
Pubmed

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.

ABCC3 ABCC2

3.66e-06267225788542
Pubmed

Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma.

ABCC3 ABCC2

3.66e-06267211745434
Pubmed

Analysis of dystrophin in fast- and slow-twitch skeletal muscles from mdx and dy2J mice at different ages.

LAMA2 DMD

3.66e-0626722183046
Pubmed

Immunohistochemical Assessment of the Expression of Biliary Transportation Proteins MRP2 and MRP3 in Hepatocellular Carcinoma and in Cholangiocarcinoma.

ABCC3 ABCC2

3.66e-06267229464551
Pubmed

Quantitative morphology of mast cells in skeletal muscle of normal and genetically dystrophic mice.

LAMA2 DMD

3.66e-0626729066911
Pubmed

Muscle protein synthesis, mTORC1/MAPK/Hippo signaling, and capillary density are altered by blocking of myostatin and activins.

MTOR DMD

3.66e-06267223115080
Pubmed

Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.

ABCC3 ABCC2

3.66e-06267230959153
Pubmed

Laminin-alpha2 but not -alpha1-mediated adhesion of human (Duchenne) and murine (mdx) dystrophic myotubes is seriously defective.

LAMA2 DMD

3.66e-0626729188790
Pubmed

Dose-dependent disposition of methotrexate in Abcc2 and Abcc3 gene knockout murine models.

ABCC3 ABCC2

3.66e-06267221841039
Pubmed

Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the in vivo elimination of methotrexate and its main toxic metabolite 7-hydroxymethotrexate.

ABCC3 ABCC2

3.66e-06267219088030
Pubmed

Diseased muscles that lack dystrophin or laminin-alpha2 have altered compositions and proliferation of mononuclear cell populations.

LAMA2 DMD

3.66e-06267215817132
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

3.66e-06267232357925
Pubmed

Muscular dystrophies: diseases of the dystrophin-glycoprotein complex.

LAMA2 DMD

3.66e-0626727481760
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

3.66e-06267219410201
Pubmed

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy.

DMD RYR2

3.66e-06267230181262
Pubmed

Muscle fiber growth and necrosis in dystrophic muscles: a comparative study between dy and mdx mice.

LAMA2 DMD

3.66e-0626723440862
Pubmed

Cytoplasmic gamma-actin contributes to a compensatory remodeling response in dystrophin-deficient muscle.

LAMA2 DMD

3.66e-06267216565216
Pubmed

The decrease of expression of ryanodine receptor sub-type 2 is reversed by gentamycin sulphate in vascular myocytes from mdx mice.

DMD RYR2

3.66e-06267219298530
Pubmed

Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.

LAMA2 DMD

3.66e-0626729334342
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MDN1 WARS1 P4HB MTOR POLA1 KRI1 MACF1 ASCC3 SEC23A

4.45e-0665367922586326
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

SYNE1 DNAH17 MACF1

7.61e-062067321689717
Pubmed

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.

ABCC3 ABCC2

1.10e-05367212628490
Pubmed

Increased multidrug resistance-associated protein activity in mononuclear cells of patients with systemic lupus erythematosus.

ABCC3 ABCC2

1.10e-05367218799096
Pubmed

Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.

ABCC3 ABCC2

1.10e-05367217273943
Pubmed

MREG suppresses thyroid cancer cell invasion and proliferation by inhibiting Akt-mTOR signaling.

MREG MTOR

1.10e-05367228698135
Pubmed

Proinflammatory signals and the loss of lymphatic vessel hyaluronan receptor-1 (LYVE-1) in the early pathogenesis of laminin alpha2-deficient skeletal muscle.

LAMA2 DMD

1.10e-05367220876525
Pubmed

Dystroglycan is not required for localization of dystrophin, syntrophin, and neuronal nitric-oxide synthase at the sarcolemma but regulates integrin alpha 7B expression and caveolin-3 distribution.

LAMA2 DMD

1.10e-05367211741881
Pubmed

Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse.

LAMA2 DMD

1.10e-0536722014247
Pubmed

Spontaneous opening of the acetylcholine receptor channel in developing muscle cells from normal and dystrophic mice.

LAMA2 DMD

1.10e-0536728568931
Pubmed

Dystroglycan expression in the wild type and mdx mouse neural retina: synaptic colocalization with dystrophin, dystrophin-related protein but not laminin.

LAMA2 DMD

1.10e-0536728568939
Pubmed

Three mouse models of muscular dystrophy: the natural history of strength and fatigue in dystrophin-, dystrophin/utrophin-, and laminin alpha2-deficient mice.

LAMA2 DMD

1.10e-05367211595512
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAH5 DNAH9

1.10e-05367215750039
Pubmed

Involvement of multiple efflux transporters in hepatic disposition of fexofenadine.

ABCC3 ABCC2

1.10e-05367218245269
Pubmed

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy.

DMD RYR2

1.10e-05367220080623
Pubmed

Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin.

LAMA2 DMD

1.10e-05367216684813
Pubmed

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.

DNAH5 DNAH9

1.10e-05367215845866
Pubmed

Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.

ABCC3 ABCC2

1.10e-05367225952649
Pubmed

Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2.

ABCC3 ABCC2

1.10e-05367219443695
Pubmed

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

LAMA2 DMD

1.10e-0536721757468
Pubmed

Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.

ABCC3 ABCC2

1.10e-05367219480556
Pubmed

BRAG2a, a Guanine Nucleotide Exchange Factor for Arf6, Is a Component of the Dystrophin-Associated Glycoprotein Complex at the Photoreceptor Terminal.

IQSEC1 DMD

1.10e-05367228744553
Pubmed

Postmortem genetic analysis of sudden unexplained death syndrome under 50 years of age: A next-generation sequencing study.

ANK2 RYR2

1.10e-05367227005929
Pubmed

Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.

ABCC3 ABCC2

1.10e-05367217485564
Pubmed

Abcc2 (Mrp2), Abcc3 (Mrp3), and Abcg2 (Bcrp1) are the main determinants for rapid elimination of methotrexate and its toxic metabolite 7-hydroxymethotrexate in vivo.

ABCC3 ABCC2

1.10e-05367219996279
Pubmed

Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.

ABCC3 ABCC2

1.10e-05367217494643
Pubmed

Overexpression of the cytotoxic T cell (CT) carbohydrate inhibits muscular dystrophy in the dyW mouse model of congenital muscular dystrophy 1A.

LAMA2 DMD

1.10e-05367217591965
Pubmed

Loss of dystrophin and β-sarcoglycan significantly exacerbates the phenotype of laminin α2 chain-deficient animals.

LAMA2 DMD

1.10e-05367224393714
Pubmed

Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.

DMD RYR2

1.10e-05367220615971
Pubmed

mTORC1-Regulated and HUWE1-Mediated WIPI2 Degradation Controls Autophagy Flux.

MTOR PSMD11 SEC23A

1.52e-052567330340022
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MDN1 WARS1 P4HB MTOR CALU POLA1 SYNE1 KRI1 PSMD11 IDH2 DNAH5 SEC23A

1.59e-051425671230948266
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

ANK2 MTOR SYNE1 IQSEC1 MACF1 RIMS2

1.74e-0528167628706196
Pubmed

Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome.

DMD NEB RYR2

1.93e-052767318468998
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

FAT1 MDN1 ANGPTL3 HYDIN PPL

1.99e-0517067523314748
Pubmed

Altered expression of the alpha7beta1 integrin in human and murine muscular dystrophies.

LAMA2 DMD

2.19e-0546729427295
Pubmed

The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.

ABCC3 ABCC2

2.19e-05467228408210
Pubmed

Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress.

ABCC3 ABCC2

2.19e-05467218038766
Pubmed

Polymorphisms of the drug transporters ABCB1, ABCG2, ABCC2 and ABCC3 and their impact on drug bioavailability and clinical relevance.

ABCC3 ABCC2

2.19e-05467225162314
Pubmed

The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.

LAMA2 DMD

2.19e-05467223274062
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

MACF1 DMD

2.19e-0546728954775
Pubmed

Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.

MTOR DMD

2.19e-05467225139234
Pubmed

Bortezomib partially improves laminin α2 chain-deficient muscular dystrophy.

LAMA2 DMD

2.19e-05467224631023
Pubmed

Inhibition of tetramethylpyrazine on P-gp, MRP2, MRP3 and MRP5 in multidrug resistant human hepatocellular carcinoma cells.

ABCC3 ABCC2

2.19e-05467219956884
Pubmed

Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.

ANK2 DMD

2.19e-05467221186323
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAH5 DNAH11

2.19e-05467218492703
Pubmed

Elevated Expression of Moesin in Muscular Dystrophies.

LAMA2 DMD

2.19e-05467228082118
Pubmed

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.

LAMA2 DMD

2.19e-05467218345011
Pubmed

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.

MTOR IDH2

2.19e-05467227624942
Pubmed

Regulation of mRNA expression of MDR1, MRP1, MRP2 and MRP3 by prototypical microsomal enzyme inducers in primary cultures of human and rat hepatocytes.

ABCC3 ABCC2

2.19e-05467216946557
Pubmed

Muscle-specific BCL2 expression ameliorates muscle disease in laminin {alpha}2-deficient, but not in dystrophin-deficient, mice.

LAMA2 DMD

2.19e-05467215757977
Pubmed

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

DNAH5 DNAH9

2.19e-05467218950741
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

MDN1 WARS1 P4HB SYNE1 STARD10 MACF1 IDH2 HYDIN SEC23A

2.40e-0580767930575818
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ABCC3 MDN1 CALU VPS13A ZDBF2 NEB RYR2 DNAH11

3.09e-0563867831182584
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PPP2R3A P4HB CALU VPS13A KRI1 NHS PSMD11 DMD L3MBTL3 UBLCP1

3.11e-051049671027880917
Pubmed

Primary Ciliary Dyskinesia

DNAH5 HYDIN DNAH11

3.26e-053267320301301
Pubmed

EMRE is essential for mitochondrial calcium uniporter activity in a mouse model.

LAMA2 DMD

3.64e-05567232017711
Pubmed

miR-410 and miR-495 Are Dynamically Regulated in Diverse Cardiomyopathies and Their Inhibition Attenuates Pathological Hypertrophy.

LAMA2 DMD

3.64e-05567226999812
Pubmed

Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles.

LAMA2 DMD

3.64e-05567210024132
Pubmed

Reduced junctional Na+/Ca2+-exchanger activity contributes to sarcoplasmic reticulum Ca2+ leak in junctophilin-2-deficient mice.

DMD RYR2

3.64e-05567225193470
Pubmed

High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.

DNAH5 DNAH11

3.64e-05567222499950
Pubmed

Ex vivo stretch reveals altered mechanical properties of isolated dystrophin-deficient hearts.

LAMA2 DMD

3.64e-05567222427904
Pubmed

ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry.

DNAH5 DNAH9

3.64e-05567223849778
Pubmed

The establishment of rotational polarity in the airway and ependymal cilia: analysis with a novel cilium motility mutant mouse.

DNAH5 DNAH9

3.64e-05567223525783
Pubmed

Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.

LAMA2 DMD

3.64e-05567231348492
Pubmed

An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.

ANK2 DMD

3.64e-05567219109891
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SYNE1 IQSEC1 MACF1 RIMS2

4.46e-051016749872452
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

FAT1 MDN1 P4HB POLA1 ARHGAP12 PSMD11 IDH2 DNAH11

5.31e-0568967836543142
Pubmed

ELF a beta-spectrin is a neuronal precursor cell marker in developing mammalian brain; structure and organization of the elf/beta-G spectrin gene.

ANK2 DMD

5.46e-05667212149647
Pubmed

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

ABCC3 ABCC2

5.46e-05667222232210
GeneFamilyDyneins, axonemal

DNAH17 DNAH5 DNAH9 DNAH11

1.41e-0717524536
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC9 ABCC2

6.29e-0613523807
GeneFamilyEF-hand domain containing|Plakins

MACF1 PPL

2.25e-048522939
GeneFamilyMaestro heat like repeat containing

MROH2A MROH2B

4.39e-0411522636
GeneFamilyEF-hand domain containing

PPP2R3A CALU MACF1 RYR2

3.60e-03219524863
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN

FAT1 PPP2R3A ANK2 CNIH1 PSMD11 AKR1A1 IDH2 ABCC2 SEC23A

1.12e-05553679M1475
CoexpressionGAO_ESOPHAGUS_25W_C1_CILIATED_EPITHELIAL_CELLS

WARS1 SYNE1 ZNF674 MACF1 DNAH5 DNAH9 HYDIN DNAH11

2.20e-05459678M39136
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

KRT15 POLA1 VPS13A HECTD4 IQSEC1 NHS ZDBF2 DMD NEB RIMS2

3.19e-056546610Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5

FAT1 KRT15 ANK2 HECTD4 IQSEC1 KRI1 ZDBF2 DMD NEB L3MBTL3

4.90e-056886610Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 MROH2A DMD NEB DNAH5 DNAH9 HYDIN RYR2 DNAH11

9.16e-121846792cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 MROH2A DMD NEB DNAH5 DNAH9 HYDIN RYR2 DNAH11

9.16e-12184679ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 MROH2A DMD NEB DNAH5 DNAH9 HYDIN RYR2 DNAH11

9.16e-121846792b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A RIMS2 DNAH5 DNAH9 HYDIN RYR2 DNAH11

6.70e-0916967712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCC3 FAT1 PPP2R3A NHS ABCC2 RIMS2 HYDIN

1.16e-081836776878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 FAT1 PPP2R3A DNM3 DNAH5 HYDIN PPL

1.56e-08191677d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 PPP2R3A SYNE1 DNM3 OCLN DNAH5 PPL

1.68e-08193677f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 PPP2R3A SYNE1 DNM3 OCLN DNAH5 PPL

1.68e-0819367742df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 SYNE1 DNM3 OCLN DNAH5 HYDIN PPL

1.74e-08194677e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 ANK2 MROH2A LAMA2 ABCC9 DMD DNAH5

1.86e-081966776bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 ANK2 MROH2A LAMA2 ABCC9 DMD DNAH5

1.86e-08196677c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

FAT1 PDE8B SYNE1 LAMA2 ABCC9 DMD RYR2

2.14e-082006778c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 PPP2R3A NHS RIMS2 DNAH5 HYDIN

1.78e-071646761cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 SYNE1 DNAH17 DNM3 HYDIN DNAH11

2.69e-07176676327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 OCLN DNAH5 DNAH9 HYDIN DNAH11

3.18e-07181676e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 OCLN DNAH5 DNAH9 HYDIN DNAH11

3.18e-0718167611cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 OCLN DNAH5 DNAH9 HYDIN DNAH11

3.18e-071816765ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT1 PDE8B LAMA2 ABCC9 DMD RYR2

3.73e-07186676888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A SYNE1 NHS RIMS2 HYDIN DNAH11

3.73e-07186676f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

ABCC3 FAT1 PPP2R3A VPS13A NHS ABCC2

3.85e-07187676d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell15-Distal-Epithelial-Secretory_progenitor|Distal / Age, Tissue, Lineage and Cell class

KRT15 STARD10 DMD OCLN DNAH5 PPL

3.97e-071886769a64fb07de611de38d6f24673feb3b81a5e85384
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 NHS OCLN DNAH5 HYDIN PPL

4.09e-07189676aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 NHS OCLN DNAH5 HYDIN PPL

4.09e-071896768977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 ANK2 SYNE1 ABCC9 DMD RYR2

4.35e-071916767853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellCiliated-cil-3|World / Class top

MEIG1 SYNE1 DNAH5 DNAH9 HYDIN DNAH11

4.49e-071926764989ebb8812b8af1870599acd932849122c05a29
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

SYNE1 DMD DNAH5 DNAH9 HYDIN DNAH11

4.63e-07193676ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

P4HB CALU IQSEC1 LAMA2 ABCC9 PPL

4.92e-07195676c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 MACF1 DNAH5 DNAH9 HYDIN DNAH11

5.06e-07196676af4cdc61830685a888a1209826c23bcf54a43084
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

SYNE1 MACF1 DNAH5 DNAH9 HYDIN DNAH11

5.06e-071966766d02d494196e3f857d53eea46d9419690d43beca
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 FAT1 PPP2R3A NHS RIMS2 HYDIN

5.22e-071976767e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SYNE1 DMD DNAH5 DNAH9 HYDIN DNAH11

5.22e-0719767674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT1 PDE8B LAMA2 ABCC9 DMD RYR2

5.70e-072006764e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT1 PDE8B SYNE1 LAMA2 ABCC9 DMD

5.70e-07200676b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

FAT1 SYNE1 LAMA2 ABCC9 DMD RYR2

5.70e-072006765ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellTracheal-10x3prime_v2-Epithelial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KRT15 STARD10 DNAH5 DNAH9 HYDIN DNAH11

5.70e-07200676e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FAT1 SYNE1 LAMA2 ABCC9 DMD RYR2

5.70e-0720067667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

FAT1 SYNE1 LAMA2 ABCC9 DMD RYR2

5.70e-072006768bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT1 PDE8B SYNE1 LAMA2 ABCC9 DMD

5.70e-0720067677631c471cc5d453a749784f838cfa6408caf09b
ToppCellmild_COVID-19_(asymptomatic)-NK_CD56bright|World / disease group, cell group and cell class (v2)

ZNF674 STARD10 ETFBKMT TNFRSF11A NEB

3.47e-06153675aff5c8ab1fb4ebc324cec02cf562b7484bb10db8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 LAMA2 ABCC9 DMD RYR2

3.82e-061566756365b69ede98bc866e996bc52736b00401aacf6f
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A LAMA2 DNAH9 HYDIN RYR2

4.32e-06160675c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MROH2A LAMA2 DNAH9 HYDIN RYR2

4.32e-0616067525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC2 NEB RIMS2 DNAH9 HYDIN

4.59e-06162675bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell368C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MREG WARS1 PDE8B TNFRSF11A PPL

5.02e-061656759d2bdc42c13c8c2a68889bec8612a1ce56f659fa
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 ETFBKMT HECTD4 ABCC9 OCLN

5.17e-0616667589e2b8453180983533faccb4275867861876d7ee
ToppCellfacs-Lung-EPCAM-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP12 STARD10 NEB DNAH5 HYDIN

5.80e-0617067582ccba6ec53f6ca0d19949a1277434c565af2983
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP12 STARD10 NEB DNAH5 HYDIN

5.80e-06170675ab19ea729ed8c8361c870e79893d1a95a1e487fa
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS2 DNAH5 DNAH9 HYDIN RYR2

6.32e-0617367566f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIMS2 DNAH5 DNAH9 HYDIN RYR2

6.32e-06173675649b08a409095592cccf31883be69c754411280d
ToppCellfacs-Trachea-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

6.87e-06176675ed788a5969edfd1199828ca5b0dd34e7f29c4d30
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DNAH17 DNM3 HYDIN DNAH11

7.06e-06177675da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KRT15 MROH2A DNAH17 ANGPTL3

7.20e-068267473349906bcc8d1a40dc03df7a490a963e85564f2
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KRT15 MROH2A DNAH17 ANGPTL3

7.20e-068267415bc417aaace2b1d680904a622fe76e95083c9ff
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

KRT15 MROH2A DNAH17 ANGPTL3

7.20e-0682674697e1da3095c8483b8181b290fa5417bdc9cee54
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCC3 FAT1 PPP2R3A NHS HYDIN

7.25e-06178675544379f5a6145429762258d426b876bb36c112f5
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

MEIG1 DNAH17 DNAH5 DNAH9 DNAH11

7.25e-06178675d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

7.45e-06179675d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

7.45e-061796758a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEIG1 KRT15 DNAH5 DNAH9 HYDIN

7.87e-0618167560a91587c59029a34e7bec1255083337fe21b72a
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH5 DNAH9 HYDIN PDZD4 DNAH11

8.30e-0618367558847e8f3a7ce3e33adba9477bcd55e769a64a90
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

ABCC3 FAT1 VPS13A NHS HYDIN

8.52e-0618467551ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

8.52e-06184675afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 LAMA2 ABCC9 DMD RYR2

8.52e-06184675689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

8.52e-06184675a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

8.52e-06184675ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

8.52e-06184675a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 LAMA2 ABCC9 DMD RYR2

8.52e-06184675327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 ZDBF2 DNAH5 DNAH9 HYDIN

8.75e-0618567505bc89a566b0db90ae06506e067190a4739a0974
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

8.98e-06186675a26811481668fa25c48a064a56c198685693ad8d
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 KRT15 DNAH5 HYDIN DNAH11

8.98e-0618667529c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

8.98e-06186675df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.21e-0618767504dba2ed09ee4180830bdf0191921696697ea234
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.21e-061876751bba994aaaa9825b54aaeaff3829850267bc4602
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.21e-06187675805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.21e-06187675d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

ANK2 PDE8B DMD NEB RYR2

9.45e-061886756d249fe92d51a19da19ec14bb2262d394255d577
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

MEIG1 SYNE1 DNAH5 DNAH9 HYDIN

9.45e-061886758f30535a32968a81a304315a49c0d90a77d36948
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 DNM3 HYDIN PPL DNAH11

9.45e-0618867563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.70e-0618967502c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.70e-06189675164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

PPP2R3A ANK2 LAMA2 DMD RYR2

9.70e-061896755e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT1 SYNE1 ABCC9 DMD RYR2

9.70e-061896757ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellPND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

9.70e-06189675a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

ABCC3 FAT1 PPP2R3A NHS ABCC2

9.70e-061896750be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MDN1 SYNE1 LAMA2 ABCC9 DMD

9.95e-061906751121eb607a984c59fbffe7220837fc178745aa55
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

FAT1 ANK2 LAMA2 DMD RYR2

9.95e-0619067593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANK2 LAMA2 ABCC9 DMD RYR2

9.95e-06190675918ad5037881212008f9f69d5df5da91fd01422c
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 DNAH5 DNAH9 HYDIN DNAH11

9.95e-061906759ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SYNE1 DNAH5 DNAH9 HYDIN DNAH11

9.95e-06190675833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MDN1 SYNE1 LAMA2 ABCC9 DMD

9.95e-06190675048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 SYNE1 DNM3 DNAH5 HYDIN

9.95e-061906753fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MEIG1 KRT15 DNAH9 HYDIN DNAH11

9.95e-0619067517829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT1 NHS ABCC9 DMD RYR2

9.95e-06190675d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

PPP2R3A ANK2 LAMA2 DMD RYR2

9.95e-06190675fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellwk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ANK2 PDE8B VPS13A RIMS2 PPL

9.95e-06190675b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

1.02e-05191675649fcb62ad15de2f83e61591e43923a717664ae7
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MEIG1 DNAH5 DNAH9 HYDIN DNAH11

1.02e-051916759621e22e14ea069f22713947c9faa2d882abe5fe
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT1 KRT15 STARD10 OCLN DNAH11

1.02e-05191675b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

PPP2R3A ANK2 LAMA2 DMD RYR2

1.02e-0519167525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ABCC3 DMD OCLN DNAH5 PPL

1.02e-0519167560ff989fe99d243a3d52955223680cdd1f1917a4
ComputationalOxidoreductases.

P4HB AKR1A1 IDH2

2.62e-0515433MODULE_519
DrugAC1L1IZE

DNAH17 DNAH5 GBA2 DNAH9 RYR2 DNAH11

2.42e-06131676CID000004799
DrugBiliton

DNAH17 DNAH5 DNAH9 DNAH11

6.39e-0641674CID000002974
Drug5-carboxyfluorescein

ABCC3 SYNE1 ABCC2

6.82e-0613673CID000123755
Drug5(6)-carboxy-2',7'-dichlorofluorescein

ABCC3 ABCC2

8.53e-062672ctd:C053897
DrugE3040 glucuronide

ABCC3 ABCC2

8.53e-062672CID000443294
DrugAC1L4BIC

ABCC3 CALU ABCC2

1.33e-0516673CID000153998
DrugPiperine [94-62-2]; Down 200; 14uM; MCF7; HT_HG-U133A

PPP2R3A CALU MACF1 PSMD11 IDH2 SEC23A

2.16e-051926764830_DN
DrugE3040 sulfate

ABCC3 ABCC2

2.55e-053672CID000443293
Drug5-carboxyfluorescein diacetate

ABCC3 ABCC2

2.55e-053672ctd:C084577
DrugCC49

MTOR CALU TNFRSF11A

3.12e-0521673CID010127622
Drugestradiol-17 beta-glucuronide

ABCC3 ABCC2 OCLN

3.60e-0522673ctd:C025483
DrugNSC406942

POLA1 ASMTL LALBA DNM3 AKR1A1 IDH2 GBA2 DNAH9 RYR2

3.98e-05565679CID000001115
DrugDaunorubicin

ANK2 MTOR AKR1A1 DMD ABCC2 RYR2

4.19e-05216676ctd:D003630
Drugmacitentan

ABCC3 ABCC2

5.10e-054672ctd:C533860
Drugoxidized glutathione

ABCC3 P4HB MTOR AKR1A1 IDH2 ABCC2

5.52e-05227676CID000000975
Drug3 alpha,6 alpha-dihydroxy-5 beta-cholanoic acid

ABCC3 SYNE1 ABCC2

8.43e-0529673CID000006747
DrugPerhexiline

ABCC3 MTOR ABCC2

8.43e-0529673ctd:D010480
Drugsyringaldehyde

SYNE1 CD180

8.48e-055672CID000008655
Drugsoybean oil, phospholipid emulsion

ABCC3 ABCC2

8.48e-055672ctd:C545823
DrugK5 1

KRT15 MTOR

8.48e-055672CID006419800
DrugNSC-167055

POLA1 SYNE1

8.48e-055672CID005383385
DiseaseMalignant neoplasm of breast

WARS1 ANK2 MTOR SYNE1 LAMA2 NHS MACF1 DMD OCLN L3MBTL3 DNAH9 UBLCP1 PDZD4

5.19e-0710746513C0006142
DiseasePrimary Ciliary Dyskinesia

DNAH5 DNAH9 HYDIN DNAH11

3.56e-0647654C4551720
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

2.86e-054652DOID:0050144 (is_implicated_in)
DiseasePrimary ciliary dyskinesia

DNAH5 HYDIN DNAH11

6.92e-0536653cv:C0008780
Diseasebilirubin metabolic disorder (biomarker_via_orthology)

ABCC3 ABCC2

9.96e-057652DOID:2741 (biomarker_via_orthology)
DiseaseMuscular Dystrophy

LAMA2 DMD

1.33e-048652C0026850
DiseaseVENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 1 (disorder)

ANK2 RYR2

2.13e-0410652C1631597
DiseaseTachycardia, Ventricular

ABCC9 RYR2

2.59e-0411652C0042514
Diseaseglycochenodeoxycholate glucuronide (1) measurement

ABCC3 ABCC2

3.67e-0413652EFO_0800474
DiseaseX-24588 measurement

ABCC3 ABCC2

3.67e-0413652EFO_0800898
DiseaseKartagener syndrome (implicated_via_orthology)

DNAH5 DNAH11

4.27e-0414652DOID:0050144 (implicated_via_orthology)
Diseasebilirubin measurement

ZNF14 PPP2R3A MROH2A ABCC9 ABCC2 DNAH11

4.28e-04442656EFO_0004570
Diseasesusceptibility to mononucleosis measurement

MDN1 DMD RYR2

4.82e-0469653EFO_0008403
DiseaseSitus ambiguus

DNAH5 DNAH9

4.93e-0415652C0266642
DiseaseX-21441 measurement

ABCC3 ABCC2

6.36e-0417652EFO_0800814
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 LAMA2

6.36e-0417652DOID:9884 (is_implicated_in)
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH17 DNAH9

7.98e-0419652DOID:10003 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ABCC3 FAT1 ANK2 SYNE1 VPS13A DMD ABCC2

8.81e-04702657C0009402
Diseaseend stage renal disease (implicated_via_orthology)

MTOR ABCC2

8.85e-0420652DOID:783 (implicated_via_orthology)
Diseasemuscular dystrophy (implicated_via_orthology)

LAMA2 DMD

9.77e-0421652DOID:9884 (implicated_via_orthology)
Diseasestatus epilepticus (implicated_via_orthology)

MTOR IDH2

9.77e-0421652DOID:1824 (implicated_via_orthology)
DiseaseBronchiectasis

DNAH5 DNAH11

1.07e-0322652C0006267
DiseaseBrugada Syndrome (disorder)

ANK2 ABCC9

1.28e-0324652C1142166
Diseaseergothioneine measurement

RIMS2 DNAH5

1.50e-0326652EFO_0021163
Diseaselung small cell carcinoma (is_implicated_in)

FAT1 MTOR

1.74e-0328652DOID:5409 (is_implicated_in)
DiseaseGlioblastoma Multiforme

FAT1 MTOR IDH2

1.91e-03111653C1621958

Protein segments in the cluster

PeptideGeneStartEntry
TLCKELLSKQDHYDW

DNAH11

2051

Q96DT5
LKDIQTKDVELYEHW

ABCC9

896

O60706
KEETKDWILPSDYDH

CALU

251

O43852
LRIELEDWKDNKHYI

ANGPTL3

331

Q9Y5C1
ACWHELLSYLEKANK

DMD

1266

P11532
WYKENLHKLEGSEET

CD180

591

Q99467
VKELIEEWSHALYLK

RBM43

276

Q6ZSC3
EEWSHALYLKLRKET

RBM43

281

Q6ZSC3
KSNILWDKEHIYDEQ

OCLN

276

Q16625
YRHPLEEKDLWSLKE

ABCC3

231

O15438
KHFSWDKYLEETNSL

L3MBTL3

446

Q96JM7
LLKYWLERDGKHATD

ANK2

3616

Q01484
KLEKSLDHETTKWYQ

FAT1

2761

Q14517
ATLLDKYWTKIHLDN

MDN1

461

Q9NU22
WDLEFSLYEAKIKNL

NLRP10

561

Q86W26
KFSELSEELLWEYVH

ASMTL

151

O95671
PDYWALAHKEDKADT

IQSEC1

341

Q6DN90
LTAESLSWYKDDEEK

DNM3

551

Q9UQ16
SEYHLWEGQKESLEK

KIAA0232

881

Q92628
EAVHADWKEYLNLLI

PPL

296

O60437
KAWLLEEESLYDLAA

PDZD4

431

Q76G19
LADNYKHWKTLDDLK

PDE8B

861

O95263
DYWLAHKALCTEKLE

LALBA

121

P00709
DLAKKEAEQWYLDTL

FAM161B

556

Q96MY7
DSLKELTHLKEYWND

KRI1

216

Q8N9T8
LADYKNKVDDAWDLL

LAMA2

1776

P24043
YSDEEIWKALELAHL

ABCC2

1401

Q92887
ADLEVKIHDWYQKQT

KRT15

131

P19012
IWDKLGETYKDHENI

P4HB

406

P07237
QEDHYALLVKAWETK

HECTD4

2246

Q9Y4D8
KFWELDTDHDLYISQ

PPP2R3A

906

Q06190
SQLLYLLEHTWKDAK

POLA1

736

P09884
KKLIDWLEDAESHLD

MACF1

6561

Q9UPN3
TSDYTNEKWLKHVDD

ARHGAP12

356

Q8IWW6
LETALLDDEPHWYKL

RIMS2

916

Q9UQ26
TDFDKNKIWYEHRLI

IDH2

276

P48735
EEWHALLVESKTYLE

HYDIN

1961

Q4G0P3
LCKELLSKQDHYDWG

DNAH17

2006

Q9UFH2
VNAYLIHDTADWKDL

GBA2

606

Q9HCG7
KELLSKQDHYDWGLR

DNAH9

2031

Q9NYC9
YDEDLADSLHQWLKK

ETFBKMT

191

Q8IXQ9
ETDEYQSWKRSHKKA

FAM186A

451

A6NE01
TIYNAEHLKEEWNKS

RNF103

216

O00237
KSWIETEEHYFEDKL

RYR2

3626

Q92736
IDKVDTLHYAWEKLL

DNAH5

1296

Q8TE73
EKLHEWEDALVAYDK

MTOR

1451

P42345
EKEWEREKAVSLHLY

MROH2A

961

A6NES4
VSHAKKWSEEIENLY

MEIG1

11

Q5JSS6
TDDEKYLWKDLTLDQ

WARS1

196

P23381
KIVWEFEQLYHSLKE

TRIM27

181

P14373
LHDIEYRKKWDSNVI

STARD10

86

Q9Y365
KHLKSELWIYLQDAD

SYNE1

4136

Q8NF91
ESTHYADLWLLNDLK

NHS

941

Q6T4R5
AKDSEEWQKLNYDIH

MREG

81

Q8N565
IIHAAEEKDWKTAYS

PSMD11

216

O00231
WLLNQYKDKEIDFHV

MROH2B

236

Q7Z745
RSWHDIDKDNAKYVK

SEC23A

311

Q15436
DSTHYKETWKALEAL

AKR1A1

136

P14550
RDDNKWIKLHADQEY

ASCC3

2066

Q8N3C0
WHIIAFDELKTDYKN

CNIH1

26

O95406
KLLDYLNHDWKSEYH

VPS13A

2156

Q96RL7
DEKEAAQWLHKLYQE

AGPAT3

266

Q9NRZ7
KEINLWKEDHIYLED

ZDBF2

1386

Q9HCK1
KLDDFLDLNHKYWER

UBLCP1

296

Q8WVY7
EQIDHYKESQDKFLW

ZNF674

91

Q2M3X9
YLDSWNEEDKCLLHK

TNFRSF11A

76

Q9Y6Q6
EEWALLDSSQKKLYE

ZNF14

16

P17017
LYTEAWDNDKKTIHV

NEB

3451

P20929