Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

LMNB1 SYNM DSP ACTBL2 SPTB TUBAL3

1.48e-05130816GO:0005200
GeneOntologyBiologicalProcessendomembrane system organization

ATP8B4 GBF1 MAPK15 LMNB1 MYO5A SPTB TJAP1 PRKCD FHIP1B STX11 TMCC1 TMED3

1.33e-056728212GO:0010256
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KNTC1 DST LMNB1 MYO5A SYNM DSP ACTBL2 DNAI7 CCDC57 CSPP1 TUBAL3 TBCA DNAH11 KPTN

9.65e-068998214GO:0099513
GeneOntologyCellularComponentsupramolecular fiber

KNTC1 COL6A3 DST LMNB1 MYO5A SYNM DSP ACTBL2 DNAI7 CCDC57 CSPP1 TUBAL3 TBCA DNAH11 KPTN

4.79e-0511798215GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

KNTC1 COL6A3 DST LMNB1 MYO5A SYNM DSP ACTBL2 DNAI7 CCDC57 CSPP1 TUBAL3 TBCA DNAH11 KPTN

5.18e-0511878215GO:0099081
DomainTEX28/TMCC

TMCC2 TMCC1

1.08e-044802IPR019394
DomainTmemb_cc2

TMCC2 TMCC1

1.08e-044802PF10267
DomaintRNA-bd_arm

DSP PPFIA2 PIBF1

1.44e-0424803IPR010978
DomainSpectrin_repeat

DST DSP SPTB

2.55e-0429803IPR002017
Domain-

DST DSP

2.69e-0468023.90.1290.10
DomainSpectrin/alpha-actinin

DST DSP SPTB

3.43e-0432803IPR018159
DomainSPEC

DST DSP SPTB

3.43e-0432803SM00150
DomainPlectin_repeat

DST DSP

3.75e-047802IPR001101
DomainPlectin

DST DSP

3.75e-047802PF00681
DomainPLEC

DST DSP

3.75e-047802SM00250
DomainCadherin_C

PCDHGA6 PCDHGA5 PCDHB14

7.70e-0442803IPR032455
DomainCadherin_C_2

PCDHGA6 PCDHGA5 PCDHB14

7.70e-0442803PF16492
DomainHAT

PRPF6 XAB2

7.97e-0410802IPR003107
DomainHAT

PRPF6 XAB2

7.97e-0410802SM00386
DomainTPR_8

PRPF6 GTF3C3 XAB2

1.52e-0353803PF13181
Domain-

GBF1 FBXO8

1.83e-03158021.10.1000.11
DomainSec7

GBF1 FBXO8

1.83e-0315802PF01369
DomainSec7_alpha_orthog

GBF1 FBXO8

1.83e-0315802IPR023394
DomainSec7

GBF1 FBXO8

2.09e-0316802SM00222
DomainGGL

RGS6 RGS7

2.09e-0316802SM00224
DomainG-gamma

RGS6 RGS7

2.09e-0316802PF00631
Domain-

RGS6 RGS7

2.09e-03168024.10.260.10
DomainGprotein-gamma

RGS6 RGS7

2.09e-0316802IPR001770
DomainG_PROTEIN_GAMMA

RGS6 RGS7

2.09e-0316802PS50058
DomainSEC7

GBF1 FBXO8

2.09e-0316802PS50190
DomainSec7_dom

GBF1 FBXO8

2.09e-0316802IPR000904
DomainActin_CS

ACTR5 ACTBL2

2.09e-0316802IPR004001
DomainG-protein_gamma-like_dom

RGS6 RGS7

2.09e-0316802IPR015898
DomainACTINS_2

ACTR5 ACTBL2

2.36e-0317802PS00432
DomainCadherin_2

PCDHGA6 PCDHGA5 PCDHB14

2.73e-0365803PF08266
DomainCadherin_N

PCDHGA6 PCDHGA5 PCDHB14

2.73e-0365803IPR013164
Domain-

RGS6 RGS7

3.96e-03228021.10.196.10
DomainDEP

RGS6 RGS7

3.96e-0322802PF00610
DomainDEP

RGS6 RGS7

3.96e-0322802PS50186
DomainRGS_subdom1

RGS6 RGS7

3.96e-0322802IPR024066
DomainDEP

RGS6 RGS7

3.96e-0322802SM00049
DomainActinin_actin-bd_CS

DST SPTB

4.32e-0323802IPR001589
DomainDEP_dom

RGS6 RGS7

4.32e-0323802IPR000591
DomainSpectrin

DST SPTB

4.32e-0323802PF00435
DomainACTININ_2

DST SPTB

4.32e-0323802PS00020
DomainACTININ_1

DST SPTB

4.32e-0323802PS00019
DomainLeu-rich_rpt_typical-subtyp

PPP1R7 CNTRL NYX SLITRK1

7.05e-03177804IPR003591
DomainLRR_TYP

PPP1R7 CNTRL NYX SLITRK1

7.05e-03177804SM00369
DomainActin

ACTR5 ACTBL2

7.77e-0331802IPR004000
DomainActin

ACTR5 ACTBL2

7.77e-0331802PF00022
DomainACTIN

ACTR5 ACTBL2

7.77e-0331802SM00268
Pubmed

Defective retinal depolarizing bipolar cells in regulators of G protein signaling (RGS) 7 and 11 double null mice.

RGS6 NYX RGS7

5.04e-08482322371490
Pubmed

Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.

RGS6 GNB4 RGS7

1.05e-06982310339615
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KNTC1 RAD51AP1 AP1AR DST LMNB1 MYO5A DSP PCDHGA6 PCDHGA5 PPFIA2 ACTBL2 CNTRL PRPF6 CCDC57 HNRNPR

1.25e-061442821535575683
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KNTC1 ATP8B4 GBF1 SYNM TMCC2 ANKRD24 TMCC1 SLITRK1 NUP160

2.52e-0649382915368895
Pubmed

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.

DST SPTB INTS1 MCM3 GNB4

3.68e-069882534943047
Pubmed

Daam2 driven degradation of VHL promotes gliomagenesis.

VHL DAAM2

5.49e-06282229053101
Pubmed

E2-EPF UCP Possesses E3 Ubiquitin Ligase Activity via Its Cysteine 118 Residue.

VHL UBE2S

5.49e-06282227685940
Pubmed

The von Hippel-Lindau tumour-suppressor protein interaction with protein kinase Cdelta.

VHL PRKCD

5.49e-06282216669786
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

DST LMNB1 MYO5A SYNM DSP ACTBL2 MCM3 PRPF6 TRIM27 NUP160 GTF3C3 XAB2 HNRNPR

7.43e-061257821336526897
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

GBF1 LMNB1 COQ8A DSP ECHDC1 INTS1 MCM3 GNB4 PRPF6 TRIM27 NUP160 GTF3C3 HNRNPR

7.43e-061257821337317656
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

PPP1R7 SETX DST LMNB1 DSP PPFIA2 PCDHB14 INTS1 MAGEB6 HNRNPR

9.20e-06736821029676528
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

VHL PPP1R7 KNTC1 GBF1 DSP MCM3 FRYL PRPF6 SPOP NUP160 GTF3C3 HNRNPR KPTN

9.32e-061284821317353931
Pubmed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

VHL SETX FBXO8 ODAD1 TMCC2 SLC22A15 MCM3 TRIM27 STX11 CCDC57

9.87e-06742821026871637
Pubmed

A systematic study of nuclear interactome of C-terminal domain small phosphatase-like 2 using inducible expression system and shotgun proteomics.

DSP NUP160 HNRNPR

1.00e-051882326674342
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

VHL SETX DST VPS72 LMNB1 DSP ACTR5 INTS1 PRPF6 TRIM27 MXD4 XAB2 HNRNPR

1.01e-051294821330804502
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KNTC1 GBF1 DST FRYL PIBF1 TRIM27 CSPP1 NUP160

1.07e-0544682824255178
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

MYO5A DSP ACTBL2 GNB4 NUP160 TUBAL3 HNRNPR

1.45e-0533482730425250
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

AP4E1 SETX DST LMNB1 SYNM CNTRL TJAP1 MCM3 NUP160 GTF3C3

1.47e-05777821035844135
Pubmed

RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling.

RGS6 RGS7

1.64e-05382224755289
Pubmed

Von Hippel-Lindau regulates interleukin-32β stability in ovarian cancer cells.

VHL PRKCD

1.64e-05382229050245
Pubmed

The mouse Mcmd gene for DNA replication protein P1MCM3 maps to bands A3-A5 on chromosome 1 by fluorescence in situ hybridization.

DST MCM3

1.64e-0538228838817
Pubmed

Stabilization of E2-EPF UCP protein is implicated in hepatitis B virus-associated hepatocellular carcinoma progression.

VHL UBE2S

1.64e-05382230903204
Pubmed

The von hippel-lindau protein suppresses androgen receptor activity.

VHL RNF14

1.64e-05382224422631
Pubmed

Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways.

RGS6 RGS7

1.64e-05382210521509
Pubmed

Dynamics of Lamins B and A/C and Nucleoporin Nup160 during Meiotic Maturation in Mouse Oocytes.

LMNB1 NUP160

1.64e-05382228374669
Pubmed

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.

LMNB1 DSP ACTBL2 INTS1 MCM3 GNB4 PRPF6 XAB2 HNRNPR

2.35e-0565282931180492
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DST MYO5A DSP INTS1 FRYL PRPF6 NUP160 GTF3C3 XAB2

2.38e-0565382922586326
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KNTC1 ATP8B4 GBF1 MAPK15 LMNB1 DSP PRKCD MCM3 PRPF6 COASY NUP160 GTF3C3 HNRNPR

2.79e-051425821330948266
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DST LMNB1 MYO5A DSP ACTBL2 INTS1 MCM3 PRPF6 NUP160 XAB2 HNRNPR

2.84e-051024821124711643
Pubmed

The Daam2-VHL-Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation.

VHL DAAM2

3.28e-05482232792353
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYO5A COQ8A PPFIA2 ANXA4 SPTB GAS6 TMEM63C TJAP1 ANKRD24 FRYL CAMTA1 CCDC57 TMCC1

4.38e-051489821328611215
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

LMNB1 ANXA4 ECHDC1 INTS1 UBE2S GTF3C3 HNRNPR

4.58e-0540082735013556
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PITHD1 DST VPS72 MYO5A SYNM DSP SPTB RNF38 DAAM2 ANKRD24 DNAI7 XAB2

4.68e-051285821235914814
Pubmed

Egr-1 and serum response factor are involved in growth factors- and serum-mediated induction of E2-EPF UCP expression that regulates the VHL-HIF pathway.

VHL UBE2S

5.47e-05582218780286
Pubmed

GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes.

RGS6 RGS7

5.47e-05582222689652
Pubmed

VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.

VHL PRKCD

5.47e-05582221233420
Pubmed

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

LMNB1 DSP ACTBL2 GNB4 TUBAL3 HNRNPR

6.32e-0528882631501420
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

PPP1R7 GBF1 DST MYO5A DSP ACTBL2 MCM3 PRPF6 GTF3C3 TBCA HNRNPR

8.00e-051149821135446349
Pubmed

MCM proteins are negative regulators of hypoxia-inducible factor 1.

VHL MCM3

8.19e-05682221658608
Pubmed

GPR179 is required for high sensitivity of the mGluR6 signaling cascade in depolarizing bipolar cells.

NYX RGS7

8.19e-05682224790204
Pubmed

Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family.

RGS6 RGS7

8.19e-05682215897264
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

COL6A3 DST ACTBL2 SPTB NUP160

8.31e-0518782526460568
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PPP1R7 KNTC1 LMNB1 ANXA4 GNB4 PRPF6 PIBF1 NUP160 GTF3C3 XAB2 HNRNPR

8.37e-051155821120360068
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

PPP1R7 COQ8A ALDH1L2 GNB4 TRIM27 GTF3C3 TUBAL3 TMED3

9.11e-0560482838803224
Pubmed

Deubiquitylase OTUD6B Governs pVHL Stability in an Enzyme-Independent Manner and Suppresses Hepatocellular Carcinoma Metastasis.

VHL UBE2S

1.14e-04782232328410
Pubmed

Protein kinase C-beta II Is an apoptotic lamin kinase in polyomavirus-transformed, etoposide-treated pyF111 rat fibroblasts.

LMNB1 PRKCD

1.14e-04782211901153
Pubmed

Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons.

SPTB PRKCD

1.14e-0478229679146
Pubmed

Identification of novel cadherins expressed in human melanoma cells.

PCDHGA5 PCDHB14

1.14e-0478229182820
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

LMNB1 MYO5A DSP ACTBL2 SPTB MCM3 PRPF6 HNRNPR

1.17e-0462682833644029
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

KNTC1 GBF1 MYO5A DSP FRYL

1.19e-0420282533005030
Pubmed

Profiling of Parkin-binding partners using tandem affinity purification.

VGF LMNB1 ACTBL2 PRPF6 HNRNPR

1.22e-0420382524244333
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

GBF1 LMNB1 COQ8A MCM3 PRPF6 NUP160 GTF3C3 HNRNPR

1.33e-0463882833239621
Pubmed

Transmembrane and coiled-coil domain family 1 is a novel protein of the endoplasmic reticulum.

TMCC2 TMCC1

1.52e-04882224454821
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

DST LMNB1 MYO5A ACTBL2 MCM3 PRPF6 NUP160 HNRNPR

1.67e-0466082832780723
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PPP1R7 AP4E1 LMNB1 DSP CNTRL MCM3 PIBF1 FHIP1B CCDC57

1.82e-0485382928718761
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

DST FRYL TRIM27 NUP160

1.92e-0412082431413325
Pubmed

Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly.

DST DSP

1.96e-04982212482924
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SETX DST LMNB1 DSP INTS1 MCM3 PRPF6 GTF3C3 XAB2 HNRNPR

2.29e-041082821038697112
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DST MYO5A DSP TRIM27 HNRNPR

2.36e-0423482536243803
Pubmed

Generation and analysis of 280,000 human expressed sequence tags.

KNTC1 DST VPS72 TMCC2 GAS6 TMCC1

2.40e-043688268889549
Pubmed

Evolution of the regulators of G-protein signaling multigene family in mouse and human.

RGS6 RGS7 MXD4

2.42e-045182311829488
Pubmed

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

LMNB1 PRKCD MCM3 HNRNPR

2.68e-0413182434551306
Pubmed

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.

VHL LMNB1 ACTBL2 TUBAL3 HNRNPR

2.87e-0424482530349055
Pubmed

Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.

RGS6 SPTB TJAP1 CAMTA1

2.92e-0413482424324551
Pubmed

Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus.

DST DSP

2.98e-041182212802069
Pubmed

Landscape of the SOX2 protein-protein interactome.

COL6A3 DSP ACTBL2 HNRNPR

3.09e-0413682421280222
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

SETX LMNB1 SYNM NUP160 HNRNPR

3.21e-0425082533536335
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

ACTR5 INTS1 UBE2S PRPF6 GTF3C3 HNRNPR

3.27e-0439082617643375
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

PITHD1 DSP MCM3 FRYL PRPF6 XAB2 HNRNPR

3.29e-0455182734728620
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SETX DST LMNB1 MYO5A DSP PRKCD MCM3 PRPF6 NUP160 GTF3C3 HNRNPR

3.30e-041353821129467282
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

PPFIA2 CNTRL TJAP1 ANKRD24 FRYL TRIM27 HNRNPR

3.62e-0456082721653829
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RAD51AP1 SETX VPS72 LMNB1 DSP MCM3 PRPF6 XAB2 HNRNPR

4.14e-0495482936373674
Pubmed

The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.

AP4E1 FHIP1B

4.21e-041382232073997
Pubmed

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network.

RNF14 RNF38 UBE2S TRIM27

4.37e-0414982419549727
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

DST PPFIA2 FRYL NUP160

4.59e-0415182417043677
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

LMNB1 DSP INTS1 MCM3 PRPF6 NUP160 GTF3C3

4.61e-0458382729844126
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

SETX DSP INTS1 PRPF6 GTF3C3

4.71e-0427282531010829
Pubmed

Repression of rRNA transcription by PARIS contributes to Parkinson's disease.

COQ8A MCM3 PRPF6 NUP160 HNRNPR

4.71e-0427282525315684
Pubmed

Targeting TRIM3 deletion-induced tumor-associated lymphangiogenesis prohibits lymphatic metastasis in esophageal squamous cell carcinoma.

MYO5A PRPF6

4.91e-041482230542119
Pubmed

UBE2S, a novel substrate of Akt1, associates with Ku70 and regulates DNA repair and glioblastoma multiforme resistance to chemotherapy.

UBE2S HNRNPR

4.91e-041482227593939
Pubmed

Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.

MYO5A ACTBL2 TRIM27

5.43e-046782329863498
Pubmed

Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.

LMNB1 DSP ACTBL2 HNRNPR

5.58e-0415982434537242
Pubmed

A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility.

LMNB1 MCM3

5.65e-041582214996723
Pubmed

LINC00941 promotes pancreatic cancer malignancy by interacting with ANXA2 and suppressing NEDD4L-mediated degradation of ANXA2.

ACTBL2 TRIM27

5.65e-041582235977942
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGA6 PCDHGA5 PCDHB14

5.67e-046882311230163
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

AP4E1 AP1AR DST TJAP1 FHIP1B

5.82e-0428582534369648
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

GBF1 COQ8A DSP UBE2S GTF3C3

6.10e-0428882523383273
Pubmed

Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia.

DSP MCM3 TBCA

6.17e-047082335008187
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

LMNB1 MYO5A DSP MCM3 PRPF6 NUP160 TBCA HNRNPR

6.18e-0480382836517590
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DST LMNB1 DSP ANXA4 ACTBL2 CNTRL MCM3 DAAM2

6.38e-0480782830575818
Pubmed

Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.

AP4E1 KPTN

6.45e-041682223870131
Pubmed

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.

AP4E1 MYO5A FHIP1B

6.70e-047282334882091
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

KNTC1 MYO5A DSP

6.70e-047282325917818
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGA6 PCDHGA5 PCDHB14

6.70e-047282310380929
Pubmed

The DNA sequence and analysis of human chromosome 6.

DST DSP ECHDC1 TJAP1 MCM3 DAAM2 TRIM27

6.75e-0462282714574404
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGA6 PCDHGA5 PCDHB14

7.26e-047482310817752
Pubmed

A functional screen to identify novel effectors of hematopoietic stem cell activity.

VPS72 TRIM27

7.30e-041782219379700
Pubmed

Congenital Muscular Dystrophy Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

COL6A3 ITGA7

7.30e-041782220301468
Pubmed

Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.

GNB4 RGS7

7.30e-041782219376773
Pubmed

Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.

PPP1R7 COQ8A FRYL PRPF6

7.81e-0417482429669786
InteractionDISC1 interactions

AP4E1 DST SYNM ACTBL2 FRYL PIBF1 TRIM27 STX11 CCDC57 NUP160

9.38e-064298210int:DISC1
InteractionPRPF18 interactions

TSNAXIP1 DAAM2 PIBF1 TRIM27 STX11 CCDC57

9.51e-06120826int:PRPF18
InteractionGOLGA1 interactions

AP4E1 AP1AR GBF1 DST TJAP1 PIBF1 CSPP1

9.72e-06183827int:GOLGA1
GeneFamilyTransmembrane and coiled-coil domain containing

TMCC2 TMCC1

2.43e-053522774
GeneFamilyEF-hand domain containing|Plakins

DST DSP

2.25e-048522939
GeneFamilyClustered protocadherins

PCDHGA6 PCDHGA5 PCDHB14

8.26e-046452320
GeneFamilyRegulators of G-protein signaling

RGS6 RGS7

1.65e-0321522720
CoexpressionPUJANA_XPRSS_INT_NETWORK

KNTC1 RAD51AP1 LMNB1 CNTRL UBE2S TBCA

1.48e-05168826M18811
CoexpressionGSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP

RAD51AP1 LMNB1 MYO5A ANXA4 MCM3 CSPP1

2.72e-05187826M2984
CoexpressionGSE14308_TH1_VS_TH17_DN

PITHD1 COL6A3 CNTRL INTS1 SPOP TSPAN5

3.96e-05200826M3374
CoexpressionGSE3982_MAST_CELL_VS_TH2_DN

PPP1R7 LMNB1 ECHDC1 MCM3 FRYL XAB2

3.96e-05200826M5456
CoexpressionBRUINS_UVC_RESPONSE_LATE

COL6A3 FBXO8 LMNB1 MYO5A ECHDC1 SLC22A15 RNF38 MCM3 DAAM2 SPOP COASY RGS7 TSPAN5

4.92e-0511368213M2247
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SETX GBF1 DST LMNB1 FRYL SPOP PIBF1 TMCC1 NUP160 RGS7 TSPAN5

7.15e-058568211M4500
CoexpressionBRUINS_UVC_RESPONSE_LATE

COL6A3 FBXO8 LMNB1 MYO5A ECHDC1 SLC22A15 RNF38 MCM3 DAAM2 SPOP COASY RGS7 TSPAN5

8.43e-0511988213MM1062
CoexpressionBROWNE_HCMV_INFECTION_24HR_DN

COL6A3 DST ANXA4 GAS6 MXD4

9.37e-05145825M14098
CoexpressionVANDESLUIS_NORMAL_EMBRYOS_UP

PPFIA2 ACTBL2

9.61e-055822MM908
CoexpressionVANDESLUIS_NORMAL_EMBRYOS_UP

PPFIA2 ACTBL2

9.61e-055822M2303
CoexpressionMARKEY_RB1_ACUTE_LOF_UP

RAD51AP1 COL6A3 GAS6 UBE2S MCM3 HNRNPR

1.01e-04237826M15606
CoexpressionMARKEY_RB1_ACUTE_LOF_UP

RAD51AP1 COL6A3 GAS6 UBE2S MCM3 HNRNPR

1.08e-04240826MM976
ToppCellMultiple_Sclerosis-Other-RBC|Multiple_Sclerosis / Disease, Lineage and Cell Type

RNF14 PITHD1 RGS6 SPTB TMCC2 TSPAN5

9.94e-0717982615763dc59ee6186416e203ffbb450ae4608eba59
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSNAXIP1 MAPK15 ODAD1 CCDC57 CSPP1 DNAH11

1.17e-06184826264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSNAXIP1 MAPK15 ODAD1 CCDC57 CSPP1 DNAH11

1.17e-06184826d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSNAXIP1 MAPK15 ODAD1 CCDC57 CSPP1 DNAH11

1.17e-0618482622010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSNAXIP1 MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

1.59e-061948264a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TSNAXIP1 MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

1.63e-06195826e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSNAXIP1 MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

1.73e-0619782674a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellMS-Multiple_Sclerosis-Others-RBC|Multiple_Sclerosis / Disease, condition lineage and cell class

RNF14 PITHD1 RGS6 SPTB TMCC2 TSPAN5

1.84e-06199826b9e7549f67bc33284bacf9a160b3916651659809
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RGS6 SYNM PPFIA2 SPTB DAAM2 ITGA7

1.84e-06199826c2903b1a4b91e94bbdaa909bacefe901255cf248
ToppCellLPS_anti-TNF-Endothelial-Endothelial-FOXM1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KNTC1 RAD51AP1 LMNB1 CNTRL UBE2S MCM3

1.84e-0619982698575fcce726589e93fbb4df1aab03e57cb56076
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

KNTC1 RAD51AP1 LMNB1 CNTRL UBE2S MCM3

1.84e-06199826be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KNTC1 RAD51AP1 LMNB1 CNTRL UBE2S MCM3

1.89e-062008269bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellHealthy_donor-RBC|Healthy_donor / disease group, cell group and cell class (v2)

PITHD1 RGS6 PCDHGA5 SPTB TSPAN5

9.71e-06154825e080d5104fe6f3f6ef617bbcdccf1332ab7231e1
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

RGS6 SYNM PPFIA2 SPTB ITGA7

1.17e-05160825fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCelldroplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATP8B4 DSP SPTB SLC22A15 RNF38

1.36e-0516582594a5211072464fc24592bb107a853ce832e816fe
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSNAXIP1 MAPK15 ODAD1 CSPP1 DNAH11

1.48e-051688259a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGF PPFIA2 PCDHB14 DAAM2 DNAI7

1.52e-0516982587116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

RGS6 SYNM PPFIA2 DAAM2 ITGA7

1.80e-051758251125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RNF14 PITHD1 RGS6 SPTB TMCC2

1.85e-051768259af82b976e6a14a3ef7aa50f1f7af2463e5aa5d2
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PITHD1 RGS6 SPTB TMCC2 TSPAN5

2.12e-05181825577bf37a6594fad01251d2c66d8ccda8e949b6cf
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PITHD1 RGS6 SPTB TMCC2 TSPAN5

2.12e-05181825f5dc7a650afe8837cb424981e50ad2c8b18c7c32
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

2.17e-051828257ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ATP8B4 MYO5A ALDH1L2 PPFIA2 GNB4

2.29e-0518482567164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

RGS6 DSP SPTB TMCC2 TSPAN5

2.35e-05185825e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

2.35e-051858255e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellIIF-Other|IIF / Disease, Lineage and Cell Type

PITHD1 RGS6 SPTB TMCC2 TSPAN5

2.48e-05187825ae44d9261698cc0289750a546baf050f78b119b3
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

2.48e-051878252b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNF14 PITHD1 SPTB TMCC2 TSPAN5

2.48e-05187825c4ba9dfedbcf0357a8627af03f4fe1770e985a03
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

COL6A3 DST RGS6 PPFIA2 ITGA7

2.48e-05187825464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-erythrocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNF14 PITHD1 SPTB TMCC2 TSPAN5

2.48e-0518782513023661c26aaf9e42262a4ff91f2fb26e8a3eaf
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VHL RGS6 DAAM2 ITGA7 CCDC57

2.48e-05187825f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VHL RGS6 DAAM2 ITGA7 CCDC57

2.48e-051878253ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 RAD51AP1 ATP8B4 LMNB1 CNTRL

2.48e-0518782573931a5ea73799095daff100b5f18853c57c74dc
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNF14 PITHD1 SPTB TMCC2 TSPAN5

2.54e-05188825da211e7fb62fff176aa9c39061aef9ab0af6079e
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNF14 PITHD1 SPTB TMCC2 TSPAN5

2.54e-051888253c6c0eaadc474ebb218ae349b787c410f66177ab
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RNF14 PITHD1 SPTB TMCC2 TSPAN5

2.54e-051888253467149de45b47a5015486ef94bec070e9c3ffc2
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

2.54e-051888259a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellAdult-Epithelial-ciliated_cell|Adult / Lineage, Cell type, age group and donor

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

2.60e-05189825b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RGS6 PPFIA2 SPTB DAAM2 ITGA7

2.67e-05190825d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

COL6A3 RGS6 PPFIA2 DAAM2 ITGA7

2.74e-0519182504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Megakaryocytic-erythropoietic / Lineage, cell class and subclass

RNF14 PITHD1 SPTB TMCC2 TSPAN5

2.95e-05194825f0ababe8daa57f6827a3e2e72c884d9e8b2687a3
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

RGS6 SYNM PPFIA2 DAAM2 ITGA7

2.95e-051948255e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

KNTC1 RAD51AP1 LMNB1 SPTB TSPAN5

3.02e-05195825764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.02e-0519582579dc031258579ea328181dda33710dd897f1064a
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

3.02e-051958253486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

3.10e-05196825de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.10e-05196825686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.10e-0519682567aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.10e-05196825ca56311edc6788e032e7635fa69b1e07035202b5
ToppCellSevere_COVID-19-Epithelial-Ciliated|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.10e-051968251cdef976a754c90d18b6149d367bd64e6e99b0a9
ToppCellBAL-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.10e-0519682569f5081e06d84ec1d9695762df801a9d0df1984b
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

COQ8A SYNM DSP SPTB ITGA7

3.18e-0519782544e49943d62bfe622b40ad0460093d31540544df
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL6A3 RGS6 PPFIA2 DAAM2 ITGA7

3.18e-05197825cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

3.18e-0519782571fea4aa6ce96c7693fa94792d08770622873850
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

3.18e-05197825e453d085182364ca347cbcc9dc995c62c3353016
ToppCellFibroblast|World / shred by cell class for bronchial biopsy

COL6A3 SYNM ACTBL2 GAS6 ITGA7

3.18e-051978258bf9846228b6b6721b10375fe54a2fb389ff64a6
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAPK15 ODAD1 DNAI7 CSPP1 DNAH11

3.18e-05197825d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNM PPFIA2 GAL3ST3 ITGA7 DNAH11

3.18e-05197825ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Deuterosomal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAD51AP1 MAPK15 ODAD1 DNAI7 DNAH11

3.25e-05198825f31790442ef142f1c0c49bf3daf2d0efb193d2c9
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ODAD1 CNTRL DNAI7 CSPP1 DNAH11

3.25e-05198825ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellTracheal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RGS6 SYNM SPTB DAAM2 ITGA7

3.33e-051998250a145172787f40d0fdaf21188d539ffaf7ece3e4
ToppCelldistal-1-Epithelial-Ciliated|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.33e-051998254120e4a2bc05adebe1e1e9670ed7ea55142eb83d
ToppCellBronchus_Control_(B.)-Stromal-TX-Smooth_muscle-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

RGS6 SYNM PPFIA2 DAAM2 ITGA7

3.33e-051998252c5ad62919c64ea0242e0984bb9932d2d975f4e3
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-0520082552aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 COL6A3 SPTB TMCC2 TSPAN5

3.41e-05200825b5f2892bc45fda5ae05e269b840305a608a07c37
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-0520082555c148238d5c80c1faa3428a917ae8075be2c145
ToppCellLPS_anti-TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

KNTC1 SPTB GAS6 PRKCD RGS7

3.41e-052008256a34e07e6d77fe3fdd9ff44c4b1e46a023f6d6a2
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 COL6A3 SPTB TMCC2 TSPAN5

3.41e-052008259ce1f91991637fc3af0f6a80a85e1a44276fe412
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-052008256a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-05200825af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-0520082585c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellLung_Parenchyma-Severe-Hematopoietic|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PITHD1 COL6A3 SPTB TMCC2 TSPAN5

3.41e-05200825fdf3e60cf94f398a56c0fa72813d0459f5ce081b
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_ciliated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-0520082573ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-0520082512bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-05200825ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PITHD1 COL6A3 SPTB TMCC2 TSPAN5

3.41e-05200825199165be1aef8497af71b74690a11de18fbe073c
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-05200825a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSNAXIP1 MAPK15 ODAD1 DNAI7 DNAH11

3.41e-05200825918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellParenchyma_COVID-19-Stromal-TX-Erythrocytes|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PITHD1 COL6A3 SPTB TMCC2 TSPAN5

3.41e-05200825a9edac2f5e009662df452ec032a80e855cdac28f
ToppCellMS-IIF-Others|IIF / Disease, condition lineage and cell class

PITHD1 RGS6 SPTB TMCC2 TSPAN5

3.41e-05200825e585ac220594f860f2fa7036bb23b165e2d74a41
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SYNM PRKCD GNB4 ITGA7

1.10e-041348244ef5f395e321cf04e56560be2502a8aa157682f4
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-2|TCGA-Colorectal / Sample_Type by Project: Shred V9

TSNAXIP1 ODAD1 SPTB DNAI7

1.37e-04142824959af19add016f21c814c28604d0177b88ebed12
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|Erythro-cells / Lineage, cell class and subclass

RNF14 RGS6 TMCC2 TSPAN5

1.45e-041448247fbedc65314cfb06bcc527d794b5de7858f7c5ec
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-late_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RNF14 PITHD1 SPTB TSPAN5

1.45e-04144824ca365380ccf5e60d2e3f6272059ff0531759612d
ToppCellHealthy_donor-RBC|World / disease group, cell group and cell class (v2)

PITHD1 PCDHGA5 SPTB TSPAN5

1.70e-041508241e1a497ec4b048f7e9cc12dd5dd9aba7fedca9e1
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

PPFIA2 KCNK15 DAAM2 NYX

1.74e-041518245906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ODAD1 PPFIA2 ITGA7

1.78e-04152824bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNM ODAD1 PPFIA2 ITGA7

1.78e-04152824ee329249a034a969a16b26a224aa04249d67382d
ToppCellAdult-Immune-enucleated_erythrocyte|Adult / Lineage, Cell type, age group and donor

SPTB TMCC2 UBE2S TSPAN5

1.92e-04155824e2d07ee4348d2c1d3552a8d0337ea42777c31f9c
ToppCellfacs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 LMNB1 DAAM2 STX11

2.02e-041578249d4308312301cb922f156a7b6aededc9e1c62807
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DSP PCDHGA5 SPTB GAS6

2.07e-041588243bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RGS6 TJAP1 DAAM2 ITGA7

2.33e-041638248f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

KNTC1 RAD51AP1 GAS6 MCM3

2.33e-0416382447300dec94dc66e965bf71fafff0a9fd24fae968
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 RAD51AP1 LMNB1 MCM3

2.33e-041638245285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RGS6 PPFIA2 SPTB ITGA7

2.33e-0416382451dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCelldroplet-Fat-Mat-18m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMNB1 DOK3 STX11 TMCC1

2.39e-04164824a27b9b3380f29bb17c9f787423f2591f2b9cf33e
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

ATP8B4 MYO5A PRKCD DAAM2

2.50e-04166824be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSNAXIP1 MAPK15 DNAI7 TUBAL3

2.61e-04168824fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TSNAXIP1 MAPK15 DNAI7 TUBAL3

2.61e-041688247edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSNAXIP1 MAPK15 ODAD1 DNAH11

2.67e-04169824fba841664939c771881ba97f14ef1df6635c04ff
Diseasecongenital muscular dystrophy (implicated_via_orthology)

COL6A3 LMNB1

1.05e-046792DOID:0050557 (implicated_via_orthology)
Diseasealcohol-related neurodevelopmental disorder (implicated_via_orthology)

TMCC2 TMCC1

1.96e-048792DOID:0050667 (implicated_via_orthology)
DiseaseGlobal developmental delay

INTS1 PIBF1 GTF3C3 HNRNPR

4.56e-04133794C0557874
Diseaseresponse to radiation, Urinary retention

COL6A3 CAMTA1

9.38e-0417792GO_0009314, HP_0000016
DiseaseJoubert syndrome 1

PIBF1 CSPP1

1.44e-0321792C4551568
Diseasemean platelet volume

ATP8B4 MYO5A PCDHGA6 PCDHGA5 TMCC2 MCM3 FRYL CAMTA1 TBCA

1.60e-031020799EFO_0004584
DiseaseSarcosine measurement

PCDHGA6 PCDHGA5

1.73e-0323792EFO_0021668
Diseasemental development measurement

PCDHGA6 PCDHGA5

2.04e-0325792EFO_0008230

Protein segments in the cluster

PeptideGeneStartEntry
LSDHEQRELYEAARL

CAMTA1

1516

Q9Y6Y1
LSAYEAELEARLNLR

CNTRL

701

Q7Z7A1
ILRLDLAGRDLTDYL

ACTBL2

176

Q562R1
YRLADLLEENQEELA

ALDH1L2

511

Q3SY69
ENALLEAQDVELYLR

DNAH11

326

Q96DT5
KLRLEEEALYAAQRE

AP1AR

101

Q63HQ0
EGLRTLAIAYRDLDD

ATP8B4

591

Q8TF62
QERLDRLLYVQELLE

ACTR5

321

Q9H9F9
LDDALVRQDAQDLYE

ANXA4

166

P09525
LALYDSLRAEFDQLR

ANKRD24

486

Q8TF21
YDVLDESLRRAELNH

AP4E1

296

Q9UPM8
DDKLYQRDLEVALAL

RAD51AP1

91

Q96B01
LELADYEAENLARLQ

RGS6

146

P49758
ALRSFDYEQLRDLQL

PCDHGA5

516

Q9Y5G8
LLNELDRSLGRYRDE

DAAM2

256

Q86T65
ELEDNYLEYLREARR

FHIP1B

546

Q8N612
ALRSFDYEQLRDLQL

PCDHGA6

516

Q9Y5G7
LLILLEAAEYLERRD

MXD4

6

Q14582
YEDALIDEVERALRL

MAGEB6

391

Q8N7X4
LLRLAEALAFRQDLE

INTS1

1501

Q8N201
YRDLKLDNVLLDRDG

PRKCD

471

Q05655
RELYLEEALQNERDL

ECHDC1

271

Q9NTX5
AEDYRELERLALQAE

KCNK15

56

Q9H427
LLDVIRAENDRDIYL

MAPK15

76

Q8TD08
LNDALDRLEELREFA

DST

7166

Q03001
LYETELADARRALDD

LMNB1

81

P20700
CYDVRNLIDLDDQRR

TMEM63C

256

Q9P1W3
VYRDLLNRGLEDQLL

KPTN

286

Q9Y664
AYEELLNQRRLEEDR

CSPP1

246

Q1MSJ5
ERDYLLERRDLAVDF

FRYL

111

O94915
AYVDLDERAIDALRE

HNRNPR

56

O43390
RIYLDERRDVLDDLV

FBXO8

186

Q9NRD0
DSTLEAQYRRLLELD

DOK3

446

Q7L591
DDEIYSLRIIDLIDR

KNTC1

891

P50748
RLFDLRADQELLLYS

GNB4

251

Q9HAV0
EELDLLRIDRNRYLN

ODAD1

141

Q96M63
VLDDVELREAQRDYL

MCM3

6

P25205
ELREAQRDYLDFLDD

MCM3

11

P25205
LDRALDYEQEAELRL

PCDHB14

196

Q9Y5E9
AEYFDESLVLLRRLL

GAL3ST3

241

Q96A11
LEVNRRLLDLDEAAY

GAS6

646

Q14393
EEELRNLRLEYDDLR

DSP

1721

P15924
LRLNLLDLDYELAEQ

COL6A3

2006

P12111
DVLRRELALECDYQR

COQ8A

396

Q8NI60
DLERRNEELEELYLL

DNAI7

61

Q6TDU7
LQVLEERDLELERYD

CCDC57

61

Q2TAC2
LRLDEALRLYLEAFR

GBF1

776

Q92538
VALDYVLDADTDRRL

ITGA7

566

Q13683
LEELQSLRELDLYDN

PPP1R7

116

Q15435
YRRLGEEALSLQALD

SLC22A15

501

Q8IZD6
YNNLLALGTERRLDE

PPFIA2

1171

O75334
DLAELELLYLDRNSI

NYX

276

Q9GZU5
ARLELADYEAESLAR

RGS7

141

P49802
ELELRHENYDEALRL

XAB2

441

Q9HCS7
HEYRLLARLEELDLA

TRIM27

196

P14373
EVENYEALLNLAERL

RNF38

416

Q9H0F5
EERLADLASDLLLQY

VGF

321

O15240
RYERLEEQLNDLTEL

TMCC2

561

O75069
LYEDEVRELEEALRR

SYNM

201

O15061
LESENDEYERARRLL

PRPF6

651

O94906
FLDYQLDELSRQRAL

SETX

2086

Q7Z333
LLRELEETRDLNYLL

SPATA31E1

126

Q6ZUB1
LEAREDLAALERDYE

TUBAL3

426

A6NHL2
ELLRLYLNYDLLEEA

NUP160

1336

Q12769
DQLDLRRDIAYNLSL

GTF3C3

851

Q9Y5Q9
FRLENDLEELALYQI

COASY

301

Q13057
LEELNERYRLDCNLA

TJAP1

161

Q5JTD0
ELVEAELFARYDRLL

RNF14

281

Q9UBS8
DLEYLQADFNLLRDI

SLITRK1

131

Q96PX8
LYLRIDLERLQCLNE

PITHD1

31

Q9GZP4
DDLLAAADKYALERL

SPOP

271

O43791
LESLYRDIRDIQDEN

STX11

41

O75558
YRLREAQDRARAEDL

TMED3

161

Q9Y3Q3
DQLLDRYRELQLSTE

PIBF1

436

Q8WXW3
RRLDIVRSLYEDLED

VHL

176

P40337
ERYRCERLEEQLNDL

TMCC1

501

O94876
EAEYRRELALRNELI

SPTB

401

P11277
LLLENYEEYAARARL

UBE2S

136

Q16763
IRAYRDDIDLQNLID

TSPAN5

131

P62079
ELNLRSLETYERLEA

VPS72

181

Q15906
ILIADLNELRYQRED

TSNAXIP1

196

Q2TAA8
LEAAYLDLQRILENE

TBCA

71

O75347
LLNEFSRLEERYDDL

MYO5A

1081

Q9Y4I1