Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium-dependent phospholipid binding

SYT9 ESYT2 SYT3 SYT6

9.14e-0660444GO:0005544
GeneOntologyMolecularFunctionclathrin binding

SYT9 SYT3 LDLR SYT6

1.11e-0563444GO:0030276
GeneOntologyMolecularFunctionphosphatidylinositol binding

SYT9 ARHGAP9 PLEKHA5 ESYT2 SYT3 MYO10

6.37e-05316446GO:0035091
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCNN1A KCNMA1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3

6.45e-05465447GO:0046873
GeneOntologyMolecularFunctionolfactory receptor binding

RTP1 RTP2

7.08e-056442GO:0031849
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

SYT9 ARHGAP9 PLEKHA5 SYT3 MYO10

7.40e-05199445GO:1901981
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SCNN1A KCNMA1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3 PIEZO1

8.81e-05664448GO:0008324
GeneOntologyMolecularFunctionphospholipid binding

SYT9 ARHGAP9 PLEKHA5 ESYT2 SYT3 MYO10 SYT6

1.79e-04548447GO:0005543
GeneOntologyMolecularFunctiontransmembrane transporter activity

SCNN1A KCNMA1 ABCC1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3 ABCG8 PIEZO1

1.96e-0411804410GO:0022857
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCNN1A KCNMA1 ABCC1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3

2.19e-04758448GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCNN1A KCNMA1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3 PIEZO1

2.97e-04793448GO:0015075
GeneOntologyMolecularFunctiontransporter activity

SCNN1A KCNMA1 ABCC1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3 ABCG8 PIEZO1

3.99e-0412894410GO:0005215
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCNN1A KCNMA1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3

4.06e-04627447GO:0022890
GeneOntologyMolecularFunctionphosphatidylserine binding

SYT9 SYT3 SYT6

5.57e-0473443GO:0001786
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCNN1A KCNMA1 TRPV6 KCNJ3 PIEZO1

9.10e-04343445GO:0005261
GeneOntologyMolecularFunctionlipid binding

SYT9 ARHGAP9 PLEKHA5 ESYT2 SYT3 FITM2 MYO10 SYT6

1.26e-03988448GO:0008289
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R41 TAS2R5

1.61e-0327442GO:0033038
GeneOntologyMolecularFunctioncalmodulin binding

MYH15 TRPV6 SLC8A3 MYO10

1.62e-03230444GO:0005516
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate binding

SYT9 PLEKHA5 SYT3

2.40e-03121443GO:1902936
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R41 TAS2R5

2.40e-0333442GO:0008527
GeneOntologyMolecularFunctionmodified amino acid binding

SYT9 SYT3 SYT6

2.46e-03122443GO:0072341
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH15 MYO10

3.17e-0338442GO:0000146
GeneOntologyMolecularFunctionmonoatomic ion channel activity

SCNN1A KCNMA1 TRPV6 KCNJ3 PIEZO1

3.26e-03459445GO:0005216
GeneOntologyMolecularFunctionSNARE binding

SYT9 SYT3 SYT6

3.34e-03136443GO:0000149
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

SCNN1A KCNMA1 KCNJ3

3.62e-03140443GO:0099094
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC1 ABCG8

5.23e-0349442GO:0140359
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

ARHGAP9 MYO10

5.23e-0349442GO:0005547
GeneOntologyMolecularFunctionchannel activity

SCNN1A KCNMA1 TRPV6 KCNJ3 PIEZO1

5.75e-03525445GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

SCNN1A KCNMA1 TRPV6 KCNJ3 PIEZO1

5.80e-03526445GO:0022803
GeneOntologyMolecularFunctiongated channel activity

SCNN1A KCNMA1 KCNJ3 PIEZO1

6.16e-03334444GO:0022836
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCNN1A SLC8A3 SLC4A4

6.32e-03171443GO:0015081
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

SCNN1A KCNMA1 KCNJ3

8.80e-03193443GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

SCNN1A KCNMA1 KCNJ3

9.31e-03197443GO:0022834
GeneOntologyBiologicalProcesssensory perception of taste

SCNN1A RTP1 TAS2R41 TAS2R5 RTP2

3.39e-0770435GO:0050909
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of bitter taste

RTP1 TAS2R41 TAS2R5 RTP2

2.09e-0644434GO:0001580
GeneOntologyBiologicalProcesssensory perception of bitter taste

RTP1 TAS2R41 TAS2R5 RTP2

2.98e-0648434GO:0050913
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of taste

RTP1 TAS2R41 TAS2R5 RTP2

3.52e-0650434GO:0050912
GeneOntologyBiologicalProcesscalcium-ion regulated exocytosis

SYT9 TRPV6 SYT3 SYT6

2.54e-0582434GO:0017156
GeneOntologyBiologicalProcessphospholipid transport

ABCC1 XKR6 LDLR ABCG8

6.97e-05106434GO:0015914
GeneOntologyBiologicalProcessimport across plasma membrane

SCNN1A ABCC1 TRPV6 SLC8A3 KCNJ3

1.12e-04230435GO:0098739
GeneOntologyBiologicalProcessregulation of calcium ion-dependent exocytosis

SYT9 TRPV6 SYT3

1.13e-0445433GO:0017158
GeneOntologyBiologicalProcesslipid localization

ABCC1 ESYT2 XKR6 ACACB FITM2 LDLR ABCG8

1.53e-04565437GO:0010876
GeneOntologyBiologicalProcesschemical homeostasis

SCNN1A KCNMA1 TRPV6 SLC8A3 SLC4A4 ACACB TMTC4 FITM2 LDLR ABCG8

1.95e-0412494310GO:0048878
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SCNN1A TRPV6 SLC8A3 KCNJ3

2.16e-04142434GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SCNN1A TRPV6 SLC8A3 KCNJ3

2.16e-04142434GO:0098659
GeneOntologyBiologicalProcesssensory perception

RDH10 SCNN1A KCNMA1 RTP1 TAS2R41 TAS2R5 TMTC4 FZD2 RTP2

3.04e-041072439GO:0007600
GeneOntologyBiologicalProcessregulated exocytosis

SYT9 ADORA3 TRPV6 SYT3 SYT6

3.35e-04291435GO:0045055
GeneOntologyBiologicalProcessorganophosphate ester transport

ABCC1 XKR6 LDLR ABCG8

3.56e-04162434GO:0015748
GeneOntologyBiologicalProcessregulation of regulated secretory pathway

SYT9 ADORA3 TRPV6 SYT3

3.82e-04165434GO:1903305
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SCNN1A KCNMA1 ABCC1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3 PIEZO1

4.07e-041115439GO:0034220
GeneOntologyBiologicalProcessexport from cell

SYT9 ABCC1 ADORA3 TRPV6 SLC8A3 RSAD2 SLC4A4 SYT3 SYT6

5.19e-041153439GO:0140352
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SCNN1A KCNMA1 TRPV6 SLC8A3 SLC4A4 ZDHHC13 KCNJ3 PIEZO1

6.41e-04942438GO:0098655
GeneOntologyBiologicalProcessintestinal cholesterol absorption

LDLR ABCG8

7.10e-0419432GO:0030299
GeneOntologyBiologicalProcesscirculatory system process

SCNN1A KCNMA1 ABCC1 ADORA3 SLC8A3 SLC4A4 KCNJ3

7.35e-04733437GO:0003013
GeneOntologyBiologicalProcesspositive regulation of vesicle fusion

SYT9 SYT3

7.88e-0420432GO:0031340
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

SYT9 FZD2 LDLR

5.75e-0479433GO:0030669
GeneOntologyCellularComponentendoplasmic reticulum membrane

RDH10 ESYT2 RTP1 SLC8A3 RSAD2 DEGS2 FITM2 PIEZO1 RTP2

1.07e-031293439GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

RDH10 ESYT2 RTP1 SLC8A3 RSAD2 DEGS2 FITM2 PIEZO1 RTP2

1.11e-031299439GO:0098827
GeneOntologyCellularComponentsynaptic membrane

KCNMA1 ADORA3 SLC8A3 SYT3 KCNJ3 SYT6

1.16e-03583436GO:0097060
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

SYT9 FZD2 LDLR

1.17e-03101433GO:0045334
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RDH10 ESYT2 RTP1 SLC8A3 RSAD2 DEGS2 FITM2 PIEZO1 RTP2

1.29e-031327439GO:0042175
GeneOntologyCellularComponentcation channel complex

SCNN1A KCNMA1 TRPV6 KCNJ3

1.36e-03235434GO:0034703
HumanPhenoMyocardial steatosis

LDLR ABCG8

1.21e-046152HP:0006693
HumanPhenoCerebral artery atherosclerosis

LDLR ABCG8

1.21e-046152HP:0007201
HumanPhenoCoronary artery aneurysm

LDLR ABCG8

1.69e-047152HP:0030882
HumanPhenoPremature arteriosclerosis

LDLR ABCG8

2.24e-048152HP:0005177
HumanPhenoMyocardial infarction

SCNN1A LDLR KCNJ3 ABCG8

2.42e-04111154HP:0001658
HumanPhenoAcute coronary syndrome

SCNN1A LDLR KCNJ3 ABCG8

2.42e-04111154HP:0033678
HumanPhenoAortic atherosclerotic lesion

LDLR ABCG8

2.88e-049152HP:0012397
HumanPhenoDyspnea

SCNN1A TRPV6 LDLR KCNJ3 ABCG8 UBE3B MGME1

2.90e-04506157HP:0002094
HumanPhenoAbnormal internal carotid artery morphology

LDLR ABCG8

4.38e-0411152HP:3000062
HumanPhenoRenal steatosis

LDLR ABCG8

4.38e-0411152HP:0000799
HumanPhenoPrecocious atherosclerosis

LDLR ABCG8

5.25e-0412152HP:0004416
HumanPhenoLong-bone fracture

TRPV6 LEMD2

5.25e-0412152HP:0025736
HumanPhenoRecurrent long bone fractures

TRPV6 LEMD2

5.25e-0412152HP:0003084
DomainSynaptotagmin

SYT9 SYT3 SYT6

1.35e-0520443IPR001565
DomainR-trans_p

RTP1 RTP2

5.40e-055442IPR026096
Domainzf-3CxxC

RTP1 RTP2

1.13e-047442PF13695
Domainzf-3CxxC

RTP1 RTP2

1.51e-048442SM01328
DomainZnf-3CxxC

RTP1 RTP2

1.51e-048442IPR027377
DomainC2

SYT9 ESYT2 SYT3 SYT6

2.52e-04131444PF00168
DomainC2

SYT9 ESYT2 SYT3 SYT6

3.00e-04137444SM00239
DomainC2

SYT9 ESYT2 SYT3 SYT6

3.43e-04142444PS50004
Domain-

SYT9 ESYT2 SYT3 SYT6

4.02e-041484442.60.40.150
DomainC2_dom

SYT9 ESYT2 SYT3 SYT6

5.92e-04164444IPR000008
DomainIQ

MYH15 MYO10 UBE3B

1.37e-0393443PS50096
DomainTAS2R

TAS2R41 TAS2R5

1.70e-0326442PF05296
DomainT2R

TAS2R41 TAS2R5

1.70e-0326442IPR007960
DomainMYOSIN_MOTOR

MYH15 MYO10

3.61e-0338442PS51456
DomainMyosin_head

MYH15 MYO10

3.61e-0338442PF00063
DomainMyosin_head_motor_dom

MYH15 MYO10

3.61e-0338442IPR001609
DomainMYSc

MYH15 MYO10

3.61e-0338442SM00242
DomainABC_transporter_CS

ABCC1 ABCG8

4.40e-0342442IPR017871
DomainABC_TRANSPORTER_2

ABCC1 ABCG8

5.71e-0348442PS50893
DomainABC_tran

ABCC1 ABCG8

5.71e-0348442PF00005
DomainABC_TRANSPORTER_1

ABCC1 ABCG8

5.95e-0349442PS00211
DomainABC_transporter-like

ABCC1 ABCG8

6.18e-0350442IPR003439
DomainWW_DOMAIN_2

ARHGAP9 PLEKHA5

6.43e-0351442PS50020
DomainWW_DOMAIN_1

ARHGAP9 PLEKHA5

6.43e-0351442PS01159
DomainWW_dom

ARHGAP9 PLEKHA5

6.67e-0352442IPR001202
PathwayREACTOME_SENSORY_PERCEPTION

RDH10 SCNN1A KCNMA1 RTP1 TAS2R41 TAS2R5 LDLR RTP2

1.05e-04636348M41834
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SCNN1A ABCC1 TRPV6 ESYT2 SLC8A3 SLC4A4 LDLR ABCG8

1.69e-04681348MM14985
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

SCNN1A TAS2R41 TAS2R5

1.93e-0447343M42524
PathwayKEGG_TASTE_TRANSDUCTION

SCNN1A TAS2R41 TAS2R5

2.61e-0452343M5785
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SCNN1A ABCC1 TRPV6 ESYT2 SLC8A3 SLC4A4 LDLR ABCG8

2.87e-04736348M27287
PathwayWP_BILE_ACID_SYNTHESIS_AND_ENTEROHEPATIC_CIRCULATION

LDLR ABCG8

3.67e-0412342M39802
Pubmed

Genomic analysis of synaptotagmin genes.

SYT9 ESYT2 SYT3 SYT6

1.58e-091344411543631
Pubmed

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production.

RTP1 LDLR RTP2

1.05e-07844335025664
Pubmed

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.

SYT9 SYT3 SYT6

1.58e-07944310531343
Pubmed

Distinct developmental expression of synaptotagmin I and IX in the mouse brain.

SYT9 SYT3 SYT6

1.58e-07944316407767
Pubmed

Piezo1 and BKCa channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillation.

KCNMA1 PIEZO1

1.56e-06244233974928
Pubmed

Lymph node mapping in patients with bladder cancer undergoing radical cystectomy and lymph node dissection to the level of the inferior mesenteric artery.

SYT3 SYT6

1.56e-06244220002670
Pubmed

Receptor-transporting protein (RTP) family members play divergent roles in the functional expression of odorant receptors.

RTP1 RTP2

1.56e-06244228586385
Pubmed

Milk cholesterol concentration in mice is not affected by high cholesterol diet- or genetically-induced hypercholesterolaemia.

LDLR ABCG8

1.56e-06244229891894
Pubmed

Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited.

LDLR ABCG8

4.69e-06344217060690
Pubmed

Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.

SYT3 SYT6

9.37e-06444230545844
Pubmed

Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice.

RTP1 RTP2

9.37e-06444228262096
Pubmed

Synaptotagmins 3 and 7 mediate the majority of asynchronous release from synapses in the cerebellum and hippocampus.

SYT3 SYT6

1.56e-05544239116209
Pubmed

Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells.

SYT9 SYT6

2.34e-05644212860971
Pubmed

Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV.

SYT3 SYT6

2.34e-0564428626542
Pubmed

Control of plasma membrane lipid homeostasis by the extended synaptotagmins.

ESYT2 SYT3

2.34e-05644227065097
Pubmed

Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins.

SYT3 SYT6

4.36e-0584427791877
Pubmed

WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding.

SYT9 SYT3

4.36e-05844215350218
Pubmed

Common variants at 30 loci contribute to polygenic dyslipidemia.

XKR6 LDLR ABCG8

4.48e-055444319060906
Pubmed

Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.

SYT9 SYT6

5.60e-0594428901523
Pubmed

Inherited ACTH insensitivity illuminates the mechanisms of ACTH action.

RTP1 RTP2

6.99e-051044216271481
Pubmed

Members of RTP and REEP gene families influence functional bitter taste receptor expression.

RTP1 RTP2

6.99e-051044216720576
Pubmed

RTP family members induce functional expression of mammalian odorant receptors.

RTP1 RTP2

6.99e-051044215550249
Pubmed

SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.

SYT9 SYT3

8.54e-051144210734137
Pubmed

Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis.

SYT9 C6orf136

1.21e-041344217431699
Pubmed

Loss of all 3 Extended Synaptotagmins does not affect normal mouse development, viability or fertility.

ESYT2 SYT3

1.41e-041444227399837
Pubmed

Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

LDLR ABCG8

2.36e-041844223726366
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

RDH10 ABCC1 PLEKHA5 FITM2 FZD2 ZDHHC13

2.76e-0471944635337019
Pubmed

Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.

PLEKHA5 XKR6 ZDHHC13

2.80e-0410044326073538
Pubmed

A novel family of mammalian taste receptors.

TAS2R41 TAS2R5

3.24e-042144210761934
Pubmed

A Transcription Factor Etv1/Er81 Is Involved in the Differentiation of Sweet, Umami, and Sodium Taste Cells.

SCNN1A TAS2R41

3.24e-042144237045597
Pubmed

The molecular receptive ranges of human TAS2R bitter taste receptors.

TAS2R41 TAS2R5

3.89e-042344220022913
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

ABCC1 ESYT2 FITM2 FZD2 PIEZO1

4.08e-0449944522810586
Pubmed

Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos.

ABCC1 LDLR

4.24e-042444221305474
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RDH10 SFI1 GRTP1 MYO10 LDLR PIEZO1 UBE3B

4.40e-04110544735748872
Pubmed

Receptors for bitter and sweet taste.

TAS2R41 TAS2R5

4.61e-042544212139982
Pubmed

Molecular mechanisms of bitter and sweet taste transduction.

TAS2R41 TAS2R5

4.99e-042644211696554
Pubmed

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.

TAS2R41 TAS2R5

5.38e-042744212581520
Pubmed

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.

TAS2R41 TAS2R5

5.79e-042844215744053
Pubmed

Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.

XKR6 LDLR

6.21e-042944220972250
Pubmed

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.

LDLR ABCG8

6.65e-043044219936222
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCNN1A KCNMA1 KCNJ3

7.34e-0413944316985003
Pubmed

Biological, clinical and population relevance of 95 loci for blood lipids.

XKR6 LDLR ABCG8

8.46e-0414644320686565
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

LDLR ABCG8

8.55e-043444219060911
Pubmed

Evolution of bitter taste receptors in humans and apes.

TAS2R41 TAS2R5

8.55e-043444215496549
Pubmed

New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.

SCNN1A LDLR

9.06e-043544218513389
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPV6 SLC8A3

1.07e-033844230786075
Pubmed

Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.

KCNMA1 SYT9 SYT6

1.22e-0316644319906978
InteractionTSPAN18 interactions

SCNN1A FITM2 ZDHHC13

2.74e-0527443int:TSPAN18
InteractionKRTCAP3 interactions

FITM2 FZD2 ZDHHC13

5.54e-0534443int:KRTCAP3
InteractionATP2B2 interactions

MYH15 ESYT2 FZD2 TRABD LEMD2

6.92e-05198445int:ATP2B2
InteractionSYT10 interactions

SYT3 SYT6

6.95e-056442int:SYT10
Cytoband3q27.3

RTP1 RTP2

1.36e-04184423q27.3
Cytoband12q24.11

ACACB UBE3B

4.65e-043344212q24.11
Cytoband1p13.2

ADORA3 SYT6

9.05e-04464421p13.2
GeneFamilySynaptotagmins

SYT9 SYT3 SYT6

3.70e-0617333765
GeneFamilyZinc fingers 3CxxC-type|Receptor transporter proteins

RTP1 RTP2

3.22e-055332719
GeneFamilyZinc fingers 3CxxC-type|Receptor transporter proteins

RTP1 RTP2

8.98e-058332137
GeneFamilyTaste 2 receptors

TAS2R41 TAS2R5

2.29e-03393321162
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP9 PLEKHA5 MYO10

6.18e-03206333682
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 SLC4A4 ACACB MYO10 PIEZO1

3.89e-07151445f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 TRPV6 ACACB KCNJ3 PIEZO1

9.03e-07179445d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 ESYT2 SLC4A4 MYO10 PIEZO1

1.06e-06185445a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 SCNN1A SLC4A4 LDLR

3.44e-0518744471d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYT9 ESYT2 SLC4A4 PIEZO1

3.59e-05189444fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYT9 ESYT2 SLC4A4 KCNJ3

3.59e-05189444532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KCNMA1 SLC8A3 MYO10 CORT

3.98e-05194444811b382ec3da06a6bda7360abc8b633f96b2019e
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SCNN1A SLC4A4 FITM2 ZDHHC13

3.98e-051944444c40d6b50675eae52c419d69e719a9223df02ae3
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

SCNN1A SLC4A4 FITM2 ZDHHC13

3.98e-0519444499a90de637e3babec2131cdd9f05ea965d8a8f30
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KCNMA1 SLC8A3 MYO10 CORT

3.98e-05194444292ce9021678534c9eedb367b9772a9d976208a8
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCNN1A KCNMA1 LDLR PIEZO1

4.14e-05196444847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KCNMA1 SLC8A3 MYO10 CORT

4.14e-05196444760885dc608c82768fe0decd63ed9fda8315f453
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCNN1A KCNMA1 LDLR PIEZO1

4.22e-05197444d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 SCNN1A PLEKHA5 DEGS2

4.22e-05197444ec08a971e8dd9ad69359896c60ad77ff8af08fd0
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 PLEKHA5 XKR6 KCNJ3

4.30e-05198444c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 PLEKHA5 XKR6 KCNJ3

4.30e-051984448ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNMA1 PLEKHA5 XKR6 KCNJ3

4.30e-051984444ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RDH10 SCNN1A DEGS2 SLC4A4

4.39e-051994447223f853335492ca617dbec3e4b6872a8a463a45
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RDH10 SCNN1A DEGS2 SLC4A4

4.39e-05199444e03bdc7cb825e287f41b834ec6061d23c1c03b04
ToppCellNS-critical-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RDH10 SCNN1A PLEKHA5 TMEM190

4.39e-051994443b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCellControl-CD4+_T_activated|Control / Disease condition and Cell class

RSAD2 CORT RTP2

2.05e-04116443e3d1a90a229f5697b2b715574bb96790a435f73b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

RSAD2 CORT RTP2

2.15e-04118443f76fc6db7368a1e8e5e4f8535fc3dc78afe13b9b
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RSAD2 CORT RTP2

2.15e-041184430dcac16eea8e7978de370a815da9a0cdd212598e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RSAD2 CORT RTP2

2.15e-041184437da3957d102e9f9825fc2609d6d0bd9ca6a3fba4
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RSAD2 CORT RTP2

2.15e-04118443c5c6724e0e526d7c2fc8cabff4a112a900ec997f
ToppCellControl-Lymphoid_T/NK-CD4+_T_activated|Control / Disease group, lineage and cell class

RSAD2 CORT RTP2

2.21e-04119443d7352d0dafbb664619b7a1e3cd07b159fdfec197
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADORA3 ARHGAP9 FBXW10

2.67e-041274430750743574c2fca8df07e11d73e8b94579209609
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Nxph2_Sla|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH15 TRPV6 SYT6

3.13e-041344436d97fa07f55ae20c17b9d5262e893957cccc6dba
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E18.5-samps / Age Group, Lineage, Cell class and subclass

FBXW10 CORT LEMD2

3.13e-04134443a4b9163af68e92d047b0005fd2f98aa63846b65b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 TRPV6 C6orf136

3.63e-041414439a0f4bee2893da1b13ab89494e6159821d53538b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC4A4 CORT SYT6

3.86e-04144443b622b605f7ec6083ec06c8ea0fd171e07c52f3de
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEGS2 FITM2 KCNJ3

3.86e-041444431b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 ADORA3 MYO10

4.70e-04154443ce4b1e878cd88065fbfd2df18caf19703fec37d8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP9 SLC4A4 KCNJ3

4.97e-04157443f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYH15 TRPV6 XKR6

5.06e-041584437960337d87afecf2692ab65e5991f052ceddfacc
ToppCellAdult-Immune-mast_cell-D175|Adult / Lineage, Cell type, age group and donor

ARHGAP9 FITM2 C6orf136

5.16e-041594439f53fe2e0f25448d62a591c8e528e9a49b5400d5
ToppCellLPS-IL1RA-Unknown-Endothelial-Monocytes-Macrophages|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRBP1 SFI1 TMTC4

5.54e-041634436b11a3ada8725670d0489f404c8c2175ad3904e9
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEGS2 ZDHHC13 KCNJ3

5.64e-041644434307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLC4A4 GRTP1 ABCG8

5.64e-04164443583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DEGS2 ZDHHC13 KCNJ3

5.64e-041644431d84aa5b925f502ee9c5fa39714490f613a58028
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SYT3 CORT KCNJ3

5.74e-041654439795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADORA3 ARHGAP9 FBXW10

5.85e-04166443063d68f2ffb40770cb4601fa1cb6426ae26f7a37
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADORA3 ARHGAP9 FBXW10

5.85e-04166443417cfb207da08fa1a0fd5f2a13c8786628667a8e
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA-MI2(C1qb)-Tmem119-MICROGLIA_Microglia.C1qb.Tmem119-Junb_(Microglia)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADORA3 ARHGAP9 FBXW10

5.85e-04166443f28d07715e6b00ca2a0df39273c5f569744be5a8
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEGS2 C6orf136 ABCG8

6.16e-0416944308ac28c5ad8f5c5f9f54af341bf39e8f9417636e
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEGS2 C6orf136 ABCG8

6.16e-04169443e5abd41db1e6724ad900e37658fa063b8e522908
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_RSAD2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYH15 RSAD2 SYT6

6.26e-0417044363dfbc4746717132dc81b6bac868c7498fc96283
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_2|368C / Donor, Lineage, Cell class and subclass (all cells)

TMTC4 FZD2 PIEZO1

6.37e-0417144326b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RDH10 DEGS2 SLC4A4

6.37e-0417144325c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RDH10 DEGS2 SLC4A4

6.37e-04171443fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABCC1 SLC8A3 ACACB

6.37e-041714435c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBXW10 SLC4A4 ZDHHC13

6.48e-041724435401ac7739f95fb8681cfb4747ab6e447a3c2ae8
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBXW10 SLC4A4 ZDHHC13

6.48e-04172443b3da7f488d191214d7bb74fbac189fe8c29ee6cd
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC1 SLC8A3 FBXW10

6.48e-041724433a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC1 SLC8A3 FBXW10

6.48e-04172443cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBXW10 SLC4A4 ZDHHC13

6.48e-0417244374dd4a7acb2cf857fed20219e4d7dc1adfbaa398
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|367C / Donor, Lineage, Cell class and subclass (all cells)

SCNN1A DEGS2 SLC4A4

6.59e-04173443d8e965ff7e9b758876ec1521c1ccedd739e8d673
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A ADORA3 DEGS2

6.59e-04173443c31076c725f4cd912c56903592a2d9356ae59f54
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A ADORA3 DEGS2

6.59e-04173443a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SCNN1A DEGS2 SLC4A4

6.59e-04173443c2d973356c40e0284fd3bd7733a164b141c66008
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADORA3 FZD2 TRABD

6.70e-04174443eaaf17a06efc09ed4752b449827b1f0f424d3dad
ToppCellRSV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

ARHGAP9 RSAD2 FITM2

6.81e-04175443ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SCNN1A ABCC1 LDLR

6.81e-04175443f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellRSV-Healthy-1|RSV / Virus stimulation, Condition and Cluster

ARHGAP9 RSAD2 FITM2

6.81e-04175443ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

SCNN1A SLC4A4 KCNJ3

6.93e-0417644336f77d878a53b30465b0dea8333a3865dba75613
ToppCellIIH-CD8-antiviral_CD4|IIH / Condition, Cell_class and T cell subcluster

SFI1 TMTC4 LEMD2

7.04e-04177443fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCellICU-NoSEP-Myeloid-cDC1|ICU-NoSEP / Disease, Lineage and Cell Type

PLEKHA5 FBXW10 CORT

7.04e-0417744333cd2c183ee8b597012efcbcae72131ac6beaf4e
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

KCNMA1 ABCC1 SLC4A4

7.16e-04178443441d1dba720141891b11f404744c59834d80e6c5
ToppCellPosterior_cortex-Hematopoietic-MICROGLIA|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ADORA3 ARHGAP9 FBXW10

7.27e-041794435122fc794509492afde4af8b1b76d51e3070ef05
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 SCNN1A LDLR

7.27e-041794436e965e424eebef50f0202cff75f458be395cfca1
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCNN1A KCNMA1 LDLR

7.27e-04179443c833ded1f9e87be2ba2037820d92a389560b711c
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DEGS2 TMEM190 KCNJ3

7.39e-041804436b1606238417490e0d9930870a7827419d1c3737
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|368C / Donor, Lineage, Cell class and subclass (all cells)

ABCC1 ARHGAP9 MGME1

7.39e-04180443551b8de8d933d11bcd3897aeb2fd033355f958e2
ToppCellwk_15-18-Hematologic-Myeloid-APOE+_Mac2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KCNMA1 ADORA3 RSAD2

7.39e-04180443c630a121aedd09a51ea18cc6e8552eb979e5b555
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RTP1 XKR6 ACACB

7.51e-04181443e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYT9 SLC4A4 KCNJ3

7.51e-04181443b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC4A4 KCNJ3 SYT6

7.51e-041814436980ea624151da32b7f537f263e40fcb87a02e81
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 TRPV6 DEGS2

7.51e-04181443c2a8ee8679a1d71fcbff792cd516d3ce114f3ca6
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A TRPV6 DEGS2

7.63e-041824432ef6889321fd0104d277518d130e19143b3af41c
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A ABCC1 ACACB

7.75e-0418344303c7e69136d5a3b9c5b2c91733e9b1c791f45c49
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH15 SFI1 SLC4A4

7.88e-04184443ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH15 SFI1 SLC4A4

7.88e-041844432cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH15 SFI1 SLC4A4

7.88e-041844432b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDH10 FBXW10 SLC4A4

7.88e-041844436b0c110d8930df99043c3b99cf4d873985126960
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RDH10 FBXW10 SLC4A4

7.88e-0418444335928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RDH10 SCNN1A SLC4A4

7.88e-0418444301c19a830348ab0b9c02c1546a439de70ee10f97
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCNN1A SYT9 ACACB

7.88e-041844438939b6d795992775df0ff58ed1ec9d421a00bcc4
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RDH10 TRPV6 DEGS2

8.00e-04185443a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PLEKHA5 ACACB ABCG8

8.00e-041854431d874608aa2062024323512f68889219471b2f00
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCNN1A TRPV6 LDLR

8.13e-04186443d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SCNN1A KCNMA1 KCNJ3

8.13e-04186443c7983281a290201567b398e9ea6baddb96c692bb
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RDH10 ZDHHC13 PIEZO1

8.25e-0418744343ef900b76f3c38bd8ce9858201124130c743d56
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC4A4 ACACB MYO10

8.25e-04187443dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC4A4 MYO10 KCNJ3

8.25e-04187443b426a67b5669019115b58295ce7d304beeb75825
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC4A4 ACACB MYO10

8.25e-041874434d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCellsaliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RDH10 ZDHHC13 PIEZO1

8.25e-041874436e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLEKHA5 SLC4A4 ACACB

8.25e-041874433ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC4A4 ACACB MYO10

8.25e-04187443ae90c263f80c36a410150d499e268d198944a3d9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC4A4 MYO10 LDLR

8.25e-04187443a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYT9 SLC4A4 KCNJ3

8.25e-04187443e3095455d2f255854f339f6b05fa87852af0700f
Diseasefatty acid measurement

XKR6 ACACB MYO10 LDLR ABCG8 UBE3B

3.36e-05436426EFO_0005110
Diseasecholesterol to total lipids in large LDL percentage

FITM2 LDLR ABCG8

7.05e-0556423EFO_0022235
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

XKR6 ACACB LDLR

2.53e-0486423EFO_0008595, EFO_0020945
DiseaseHypercholesterolemia, Familial

LDLR ABCG8

2.98e-0418422C0020445
Diseaseclinical and behavioural ideal cardiovascular health

LDLR ABCG8

4.91e-0423422EFO_0007654
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

LDLR ABCG8

6.29e-0426422OBA_2045194
Diseasecolorectal cancer, breast carcinoma

SYT9 SFT2D1

6.29e-0426422EFO_0000305, MONDO_0005575
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

XKR6 ACACB LDLR ABCG8

6.34e-04276424EFO_0004612, EFO_0020943
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

XKR6 LDLR ABCG8

6.87e-04121423EFO_0008595, EFO_0020943
DiseaseLiver Cirrhosis, Experimental

RDH10 ADORA3 ARHGAP9 SLC4A4 ZDHHC13 ABCG8

7.49e-04774426C0023893
Diseaselevel of Sphingomyelin (d42:2) in blood serum

SLC4A4 LDLR

7.84e-0429422OBA_2045183
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

XKR6 LDLR ABCG8

7.91e-04127423EFO_0008595, EFO_0020947
Diseasearteriosclerosis (is_implicated_in)

LDLR ABCG8

8.96e-0431422DOID:2349 (is_implicated_in)
DiseaseAge-related nuclear cataract

SLC4A4 UBE3B

8.96e-0431422HP_0011142
Diseasefatty liver disease (implicated_via_orthology)

ACACB LDLR

8.96e-0431422DOID:9452 (implicated_via_orthology)
Diseasejoint hypermobility measurement

XKR6 PIEZO1

1.02e-0333422EFO_0007905
Diseaseplatelet measurement

ESYT2 SLC8A3 GRTP1 FZD2

1.04e-03315424EFO_0005036
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

XKR6 LDLR ABCG8

1.28e-03150423EFO_0004611, EFO_0020947
DiseaseHypercholesterolemia

LDLR ABCG8

1.42e-0339422C0020443
Diseasecholesterol in very small VLDL measurement

LDLR ABCG8

1.49e-0340422EFO_0022231
Diseasefree cholesterol in medium LDL measurement

LDLR ABCG8

1.49e-0340422EFO_0022268
Diseasefree cholesterol to total lipids in very small VLDL percentage

LDLR ABCG8

1.72e-0343422EFO_0022290

Protein segments in the cluster

PeptideGeneStartEntry
FSWVLLALALLAWCR

ESYT2

136

A0FGR8
TWYILSLTLCRFLAW

C6orf136

191

Q5SQH8
IRKSSLLTFLAWWFE

CORT

41

O00230
RIWLALGLCWLVSFL

ADORA3

126

P0DMS8
TCVLAWKIFSTKEWF

FBXW10

31

Q5XX13
VPAWISKVSFLRWCF

ABCG8

586

Q9H221
IFSCLTFSWLKIWGK

ACACB

11

O00763
LLWRTLKYLWTVCCH

KCNMA1

106

Q12791
AELCSQYWTKWLLRL

MGME1

311

Q9BQP7
LIFFWCLAFLWGLLI

LEMD2

381

Q8NC56
TRFARLWILTWSVLC

FZD2

241

Q14332
WCVLKDETFLWFRSK

MYO10

1196

Q9HD67
AWKRWCTQILSALSY

NRBP1

176

Q9UHY1
VKVAWAWTFCLLLPF

FITM2

61

Q8N6M3
WTLLVSRWFICLFVD

GRTP1

226

Q5TC63
WFFCTPARKLLWLVL

DEGS2

151

Q6QHC5
RMKTAFWAVLWLCTF

SCNN1A

81

P37088
ALGFLLWIVCWADLF

ABCC1

76

P33527
FCSIPWCLFWATVLL

RTP1

236

P59025
FLSLRWCLFWASLCL

RTP2

196

Q5QGT7
VLLGVSLFVSWKLCW

SYT3

66

Q9BQG1
ALVAVFLFLFWKLCW

SYT6

71

Q5T7P8
LFGVSLFVSWKLCWV

SYT9

66

Q86SS6
TFWFCSWLSVLFCVK

TAS2R41

96

P59536
TVRALWFWAFSLQAK

SFI1

841

A8K8P3
LFCWLRATFWLLATK

RSAD2

31

Q8WXG1
LLTFRAFFWWIALIK

MYH15

6

Q9Y2K3
TFKVLWAFVLAAARW

RDH10

11

Q8IZV5
LCFIFTLCAALWWHK

SFT2D1

106

Q8WV19
LWLKQRAYNLSLWCL

TAS2R5

116

Q9NYW4
SDWRVIALAALWFCL

TMTC4

351

Q5T4D3
WLDCLWIVLALLVFF

XKR6

126

Q5GH73
LLLLSCSICLFWWAK

TMEM190

91

Q8WZ59
FRLWRWLQKCELFLL

ZDHHC13

281

Q8IUH4
FWQKVRLAWGLCFLS

TRABD

206

Q9H4I3
LILCLWSKFCRWFQR

TRPV6

51

Q9H1D0
FLLLRKTNSDWWLAR

ARHGAP9

51

Q9BRR9
TSFWIKCRRWLLADA

nan

116

Q8IYB0
WYVSLACSKDLTLLW

UBE3B

116

Q7Z3V4
LEFRLWIGLWSAFLC

SLC4A4

551

Q9Y6R1
SVYLLLFLALCTWWA

PIEZO1

221

Q92508
LWKKRWFVLSDLCLF

PLEKHA5

186

Q9HAU0
LFTTLVDLKWRWNLF

KCNJ3

71

P48549
FLCLGVFLLWKNWRL

LDLR

801

P01130
GCKLATTWLFVSLWL

SLC8A3

896

P57103