Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	PDZ	IL16 RGS3 LIMK1 PDLIM3 AHNAK DLG3 RIMS2 MAST3 PDZD2	8.06e-06	141	177	9	PF00595
Domain	PDZ	IL16 RGS3 LIMK1 PDLIM3 AHNAK DLG3 RIMS2 MAST3 PDZD2	1.19e-05	148	177	9	SM00228
Domain	-	IL16 RGS3 LIMK1 PDLIM3 AHNAK DLG3 RIMS2 MAST3 PDZD2	1.33e-05	150	177	9	2.30.42.10
Domain	PDZ	IL16 RGS3 LIMK1 PDLIM3 AHNAK DLG3 RIMS2 MAST3 PDZD2	1.40e-05	151	177	9	PS50106
Domain	PDZ	IL16 RGS3 LIMK1 PDLIM3 AHNAK DLG3 RIMS2 MAST3 PDZD2	1.48e-05	152	177	9	IPR001478
Domain	Tyr-prot_kinase_Fes/Fps	FER FES	8.93e-05	2	177	2	IPR016250
Domain	Laminin_G	COL11A1 COL19A1 LAMA1 CELSR1 EGFLAM	2.20e-04	58	177	5	IPR001791
Pathway	PID_HDAC_CLASSI_PATHWAY	HDAC9 CHD3 SIRT7 SSPOP NCOR2 NFKB1	2.65e-05	66	126	6	M101
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 RAP1GAP2 DDN PHLDB1 CAMKK2 KIDINS220 SGSM2 RABGAP1L PDE4DIP NAV1 COBL DLG3 RIMBP2 MICAL3 TRAK2 MEGF11 PRRC2B PDZD2	9.20e-12	407	186	18	12693553
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CASC3 MAN2B2 ANK3 BICRA NAIP ANKMY1 CHD3 SSPOP ITGB5 TERF2IP SHKBP1 NCOR2 PHLDB1 KIDINS220 WDR11 SGSM2 KIAA1217 KIAA1328 ANKRD11 NAV1 NLRC5 COBL MICAL3 DHRSX POLK ZNF512 UTRN TMCC1 TRAPPC9 ARAP1 PDZD2 ANKS1A	1.87e-11	1489	186	32	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 FRAS1 LZTR1 BICRA MYOM3 RAP1GAP2 C15orf39 FAAP100 ITGB5 C8orf58 HIRA JAK3 NCOR2 PHLDB1 CELSR1 SGSM2 PI4KA AHNAK ANKRD11 NAV1 NLRC5 COBL MICAL3 TRAPPC9 PRRC2B ARAP1	2.68e-10	1105	186	26	35748872
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ATP6V1B2 ARHGAP32 CTNNAL1 LZTR1 ANK3 CEP290 TNS2 BCKDHB SHKBP1 NCOR2 AAAS NOP14 DDX50 WDR11 CEP72 SUPT5H PI4KA AHNAK NFKB1 KIAA1328 MICAL3 HADHB ZNF512 UTRN PRRC2B	4.71e-10	1049	186	25	27880917
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CASC3 ARHGAP32 EXPH5 PLEKHG2 SHKBP1 KSR1 LIMK1 PHLDB1 SQSTM1 PI4KA AHNAK KIAA1217 RABGAP1L MEPCE ANKRD11 NAV1 COBL UTRN TMCC1 TRAPPC9 ANKS1A	8.64e-09	861	186	21	36931259
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ATP6V1B2 ARHGAP32 IL16 FN1 ANK3 TNC BCLAF1 IARS1 ACO2 CHD3 ALDH1L1 LDHA PHLDB1 KIDINS220 PI4KA KIAA1217 SLC27A1 PDE4DIP NAV1 DLG3 RIMBP2 MICAL3 HADHB UTRN TRAPPC9 PRRC2B AGAP2	1.34e-08	1431	186	27	37142655
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ATP6V1B2 TENT4A BCLAF1 LAMA1 KIDINS220 DDX50 WDR11 PI4KA DDX20 HADHB UTRN DDX28 SMAD5	1.64e-08	313	186	13	38270169
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CASC3 PDSS2 SYNM ACO2 SCYL1 YARS2 MRPL4 SPTBN5 AAAS NOP14 DDX50 CDC40 EHMT2 SQSTM1 NT5DC2 PI4KA KIAA1217 BRD7 NAV1 DDX20 ALDH4A1 HADHB TRAK2 ZNF512 TMCC1 DDX28 PRRC2B	3.33e-08	1496	186	27	32877691
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CASC3 ARHGAP32 ANK3 BCLAF1 DDN HIRA NCOR2 CCDC13 PELP1 EHMT2 PI4KA KIAA1217 PDE4DIP BRD7 NAV1 DLG3 RIMBP2 PRRC2B AGAP2 ANKS1A	2.67e-07	963	186	20	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HDAC9 ARHGAP32 MAN2B2 SYNM EXPH5 CEP290 WDFY4 WDR11 CEP72 MICAL3 ZNF512 TMCC1 TRAPPC9 MAST3	4.93e-07	493	186	14	15368895
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	CASC3 FRAS1 TENT4A SYNM SCYL1 CHD3 LDHA FZD6 NOP14 DDX50 CDC40 PELP1 WDR11 SUPT5H MEPCE HADHB	5.27e-07	653	186	16	33742100
Pubmed	Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.	LZTR1 ALDH1L1 SPTBN5 NCOR2 CELSR1 RABGAP1L MEGF11 TRAPPC9	1.05e-06	142	186	8	19851296
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	FN1 ANK3 SYNM BCLAF1 SCYL1 LDHA ARFIP1 KIDINS220 DDX50 WDR11 EHMT2 SQSTM1 PI4KA AHNAK DLG3 PLD1 PRRC2B	1.09e-06	777	186	17	35844135
Pubmed	Association of genetic variants with hemorrhagic stroke in Japanese individuals.	LZTR1 ALDH1L1 SPTBN5 NCOR2 CELSR1 RABGAP1L MEGF11 TRAPPC9	1.11e-06	143	186	8	20198315
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HDAC9 ARHGAP32 DDN CAMKK2 RIMS2 TMCC1 ARAP1	1.26e-06	101	186	7	9872452
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CASC3 ATP6V1B2 VRK3 SIRT7 TERF2IP HIRA SHKBP1 BLVRB CELSR1 KIDINS220 NOP14 DDX50 WDR11 EHMT2 SQSTM1 PI4KA BRD7 ANKRD11 KDM2B DLG3 DDX20 UTRN TMCC1 DDX28	1.70e-06	1497	186	24	31527615
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ARHGAP32 ANK3 SYNM EXPH5 KIDINS220 SQSTM1 KIAA1217 UTRN PRRC2B ANKS1A	1.72e-06	263	186	10	34702444
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	ATP6V1B2 COL11A1 VRK3 CHD3 LDHA CFB MRPL4 BLVRB CELSR1 KIDINS220 SQSTM1 PI4KA KIAA1217 DDX28 SHISA6 PRRC2B	2.32e-06	732	186	16	34732716
Pubmed	p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.	FN1 TNC CEP290 EHMT2 SQSTM1 AHNAK HADHB UTRN	2.45e-06	159	186	8	30581152
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	ARHGAP32 ANK3 DDN CAMKK2 PI4KA AHNAK DLG3 RIMS2 SHISA6 AGAP2	3.10e-06	281	186	10	28706196
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ARHGAP32 CTNNAL1 ANK3 ARFIP1 PHLDB1 KIDINS220 PI4KA KIAA1217 COBL DLG3 MICAL3 UTRN	3.18e-06	421	186	12	36976175
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	SYNM BCLAF1 IARS1 SCYL1 LDHA BLVRB EHMT2 AHNAK KIAA1217 MICAL3 UTRN	4.28e-06	360	186	11	33111431
Pubmed	A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex.	FN1 LAMA1 PDGFC	5.19e-06	7	186	3	26988758
Pubmed	Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression.	HDAC9 RBBP8 NCOR2	8.26e-06	8	186	3	11959865
Pubmed	Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.	FN1 TNC TNN	8.26e-06	8	186	3	23055981
Pubmed	Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells.	FN1 TNC LAMA1	8.26e-06	8	186	3	19633172
Pubmed	Human transcription factor protein interaction networks.	ARHGAP32 ACTR8 BICRA IARS1 ACO2 C15orf39 CHD3 HIRA MRPL4 NCOR2 NOP14 DDX50 EHMT2 SQSTM1 NFKB1 BRD7 KDM2B HADHB ZNF512 TRAPPC9 PRRC2B SMAD5	8.99e-06	1429	186	22	35140242
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	FN1 TNC LAMA1 ITGAM	9.18e-06	25	186	4	19373938
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CEP290 CHD3 TERF2IP C9orf43 AAAS PELP1 EHMT2 SUPT5H AHNAK NFKB1 BRD7 ANKS1A	9.46e-06	469	186	12	27634302
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	ATP6V1B2 BCLAF1 CEP290 HIRA EHMT2 CEP72 SQSTM1 PI4KA AHNAK NAV1 MICAL3 HADHB ZNF512 UTRN	1.10e-05	645	186	14	25281560
Pubmed	Detection of gelatinolytic activity in developing basement membranes of the mouse embryo head by combining sensitive in situ zymography with immunolabeling.	FN1 TNC LAMA1	1.23e-05	9	186	3	22688677
Pubmed	Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.	FN1 TNC LAMA1	1.23e-05	9	186	3	9882526
Pubmed	Epiboly generates the epidermal basal monolayer and spreads the nascent mammalian skin to enclose the embryonic body.	FN1 FZD6 CELSR1	1.76e-05	10	186	3	26989131
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ACTR8 VRK3 BCLAF1 CEP290 CHD3 SIRT7 TERF2IP HIRA ZSCAN29 NCOR2 AAAS DDX50 CDC40 PELP1 EHMT2 SUPT5H AHNAK ANKRD11 KDM2B HADHB	2.23e-05	1294	186	20	30804502
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	FRAS1 FN1 TNC LAMA1 SSPOP	2.45e-05	64	186	5	22261194
Pubmed	Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.	COL11A1 FN1 ITGAM ITGB5	2.53e-05	32	186	4	23154389
Pubmed	Fer kinase limits neutrophil chemotaxis toward end target chemoattractants.	FER FES	2.84e-05	2	186	2	23355730
Pubmed	Fps/Fes and Fer non-receptor protein-tyrosine kinases regulate collagen- and ADP-induced platelet aggregation.	FER FES	2.84e-05	2	186	2	12871378
Pubmed	Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence.	HIRA SQSTM1	2.84e-05	2	186	2	39178863
Pubmed	Closing in on the biological functions of Fps/Fes and Fer.	FER FES	2.84e-05	2	186	2	11994747
Pubmed	Staphylococcal superantigen-like protein 8 (SSL8) binds to tenascin C and inhibits tenascin C-fibronectin interaction and cell motility of keratinocytes.	FN1 TNC	2.84e-05	2	186	2	23485472
Pubmed	Counterbalancing anti-adhesive effects of Tenascin-C through fibronectin expression in endothelial cells.	FN1 TNC	2.84e-05	2	186	2	28986537
Pubmed	FER and FES tyrosine kinase fusions in follicular T-cell lymphoma.	FER FES	2.84e-05	2	186	2	31746983
Pubmed	Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes.	PGR PELP1	2.84e-05	2	186	2	24469035
Pubmed	Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C.	FN1 TNC	2.84e-05	2	186	2	23313574
Pubmed	Tenascin-C and tenascin-W in whisker follicle stem cell niches: possible roles in regulating stem cell proliferation and migration.	TNC TNN	2.84e-05	2	186	2	24101721
Pubmed	Regulation of C1-Ten protein tyrosine phosphatase by p62/SQSTM1-mediated sequestration and degradation.	TNS2 SQSTM1	2.84e-05	2	186	2	25101860
Pubmed	SGSM2 inhibits thyroid cancer progression by activating RAP1 and enhancing competitive RAS inhibition.	TERF2IP SGSM2	2.84e-05	2	186	2	35264562
Pubmed	Cryptic domains of tenascin-C differentially control fibronectin fibrillogenesis.	FN1 TNC	2.84e-05	2	186	2	20708078
Pubmed	Calmodulin-dependent protein kinase kinase-beta activates AMPK without forming a stable complex: synergistic effects of Ca2+ and AMP.	CAMKK2 PRKAB1	2.84e-05	2	186	2	19958286
Pubmed	Rap1 induces cytokine production in pro-inflammatory macrophages through NFκB signaling and is highly expressed in human atherosclerotic lesions.	TERF2IP NFKB1	2.84e-05	2	186	2	26505215
Pubmed	Binding of tenascin-C to soluble fibronectin and matrix fibrils.	FN1 TNC	2.84e-05	2	186	2	7499434
Pubmed	The Adaptor Protein p62 Mediates Nuclear Factor κB Activation in Response to Inflammation and Facilitates the Formation of Prolabor Mediators in Human Myometrium.	SQSTM1 NFKB1	2.84e-05	2	186	2	27638291
Pubmed	Immunostaining Study on the Expression of NF-κB, ER, and PR in Ovarian Serous Carcinoma.	PGR NFKB1	2.84e-05	2	186	2	27171541
Pubmed	Inhibition of nuclear factor-kappaB by hyaluronan in rheumatoid chondrocytes stimulated with COOH-terminal heparin-binding fibronectin fragment.	FN1 NFKB1	2.84e-05	2	186	2	17929131
Pubmed	Analysis of WDFY4 rs7097397 and PHLDB1 rs7389 polymorphisms in Chinese patients with systemic lupus erythematosus.	WDFY4 PHLDB1	2.84e-05	2	186	2	35188604
Pubmed	Tenascin C, Fibronectin, and Tumor-Stroma Ratio in Pancreatic Ductal Adenocarcinoma.	FN1 TNC	2.84e-05	2	186	2	30451798
Pubmed	Genetic analyses of NFKB1 and OCA-B function: defects in B cells, serum IgM level, and antibody responses in Nfkb1-/-Oca-b-/- mice.	POU2AF1 NFKB1	2.84e-05	2	186	2	11120805
Pubmed	Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.	FER FES	2.84e-05	2	186	2	12901971
Pubmed	Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.	FN1 LAMA1	2.84e-05	2	186	2	16677310
Pubmed	The relationship of promoter methylation of calcium voltage-gated channel alpha 1 and interleukin-16 to primary osteoarthritis.	IL16 CACNA1G	2.84e-05	2	186	2	37259724
Pubmed	Cleft palate formation in fetal Br mice with midfacial retrusion: tenascin, fibronectin, laminin, and type IV collagen immunolocalization.	FN1 TNC	2.84e-05	2	186	2	9482226
Pubmed	De novo expression of fetal ED-A(+) fibronectin and B (+) tenascin-C splicing variants in human cardiac allografts: potential impact for targeted therapy of rejection.	FN1 TNC	2.84e-05	2	186	2	24792713
Pubmed	Muscarinic receptor activation of AMP-activated protein kinase inhibits orexigenic neuropeptide mRNA expression.	CAMKK2 PRKAB1	2.84e-05	2	186	2	18436530
Pubmed	The adhesion modulating properties of tenascin-W.	TNC TNN	2.84e-05	2	186	2	22211116
Pubmed	Combination of linkage mapping and microarray-expression analysis identifies NF-kappaB signaling defect as a cause of autosomal-recessive mental retardation.	NFKB1 TRAPPC9	2.84e-05	2	186	2	20004764
Pubmed	Changes in extra cellular matrix remodelling and re-expression of fibronectin and tenascin-C splicing variants in human myocardial tissue of the right atrial auricle: implications for a targeted therapy of cardiovascular diseases using human SIP format antibodies.	FN1 TNC	2.84e-05	2	186	2	20232238
Pubmed	Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression.	FN1 LAMA1	2.84e-05	2	186	2	25885552
Pubmed	Thrombin activates AMP-activated protein kinase in endothelial cells via a pathway involving Ca2+/calmodulin-dependent protein kinase kinase beta.	CAMKK2 PRKAB1	2.84e-05	2	186	2	16880506
Pubmed	Deficiency of decay-accelerating factor and complement receptor 1-related gene/protein y on murine platelets leads to complement-dependent clearance by the macrophage phagocytic receptor CRIg.	CR1L ITGAM CFB	3.20e-05	12	186	3	18524992
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	TNC BCLAF1 PRRT3 RIMS2 PRRC2B MAST3 AGAP2 BRWD1	3.71e-05	231	186	8	16452087
Pubmed	Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus.	PI4KA AHNAK ARAP1	4.14e-05	13	186	3	15607035
Pubmed	Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure.	LIMK1 CELSR1 COBL	4.14e-05	13	186	3	17229766
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	TNS2 NCOR2 SQSTM1 AHNAK KIAA1217 UTRN	4.33e-05	118	186	6	30979931
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ARHGAP32 ANK3 BCLAF1 IARS1 ACO2 PLPPR3 LDHA SQSTM1 PI4KA KIAA1217 RABGAP1L PDE4DIP NAV1 DLG3 HADHB TMCC1 SHISA6 AGAP2	4.40e-05	1139	186	18	36417873
Pubmed	The first draft of the endostatin interaction network.	COL11A1 FN1 LAMA1	5.25e-05	14	186	3	19542224
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	ISYNA1 FN1 LDHA CFB NCOR2 PI4KA FER DDX20 TRAPPC9 PRRC2B MAST3	5.52e-05	475	186	11	31040226
Pubmed	Bioinformatics and cellular signaling.	HDAC9 IL16 FN1 FCRLA LDHA SQSTM1 BRD7	5.94e-05	182	186	7	15102471
Pubmed	Proteome-wide characterization of N-glycosylation events by diagonal chromatography.	FN1 TNC CFB SERPINA10 KLKB1	6.00e-05	77	186	5	16944957
Pubmed	Defining the membrane proteome of NK cells.	IARS1 CEP290 SCYL1 LDHA KSR1 NCOR2 AAAS KIDINS220 NOP14 DDX50 PELP1 WDR11 PI4KA AHNAK SLC27A1 DDX20 PLD1 AGAP2	6.07e-05	1168	186	18	19946888
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	VRK3 BICRA C15orf39 ALDH1L1 NCOR2 SUPT5H BRD7 KDM2B DDX20 HADHB	6.17e-05	398	186	10	35016035
Pubmed	Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin.	FN1 TNC ACO2 LDHA	6.23e-05	40	186	4	38418556
Pubmed	ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.	COL11A1 FN1 ADAMTS14	6.53e-05	15	186	3	38871984
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	LAMA1 DDX50 CDC40 PELP1 SUPT5H MEPCE EGFLAM PRRC2B	6.66e-05	251	186	8	28077445
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	FRAS1 CHD3 LDHA HIRA DDX50 CDC40 PI4KA BRD7 HADHB UTRN	7.89e-05	410	186	10	26949251
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RBBP8 C15orf39 NCOR2 SUPT5H SQSTM1 PI4KA KIAA1217 NAV1 KDM2B DDX20 POLK PRRC2B	8.48e-05	588	186	12	38580884
Pubmed	NLRC5 attenuates inflammatory response in IL-1β-stimulated human osteoarthritis chondrocytes through the NF-κB signaling pathway.	NFKB1 NLRC5	8.50e-05	3	186	2	34438368
Pubmed	Fes mediates the IL-4 activation of insulin receptor substrate-2 and cellular proliferation.	JAK3 FES	8.50e-05	3	186	2	11160325
Pubmed	NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation.	NFKB1 TRAPPC9	8.50e-05	3	186	2	15951441
Pubmed	The Fer tyrosine kinase regulates an axon retraction response to Semaphorin 3A in dorsal root ganglion neurons.	FER FES	8.50e-05	3	186	2	18053124
Pubmed	Immunoreactivity of progesterone receptor isoform B, nuclear factor kappaB, and IkappaBalpha in adenomyosis.	PGR NFKB1	8.50e-05	3	186	2	19296948
Pubmed	CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation.	ODAD1 ODAD3	8.50e-05	3	186	2	25192045
Pubmed	The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells.	FN1 LAMA1	8.50e-05	3	186	2	22919069
Pubmed	Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects.	FZD6 CELSR1	8.50e-05	3	186	2	32356230
Pubmed	Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme.	FN1 TNC	8.50e-05	3	186	2	2440899
Pubmed	HIV-1 Tat-mediated microglial inflammation involves a novel miRNA-34a-NLRC5-NFκB signaling axis.	NFKB1 NLRC5	8.50e-05	3	186	2	30872089
Pubmed	Sequestosome 1 (p62) accumulation in breast cancer cells suppresses progesterone receptor expression via argonaute 2.	PGR SQSTM1	8.50e-05	3	186	2	32800344
Pubmed	An allelic variant of Crry in the murine Sle1c lupus susceptibility interval is not impaired in its ability to regulate complement activation.	CR1L CFB	8.50e-05	3	186	2	20660348
Pubmed	TTC25 Deficiency Results in Defects of the Outer Dynein Arm Docking Machinery and Primary Ciliary Dyskinesia with Left-Right Body Asymmetry Randomization.	ODAD1 ODAD3	8.50e-05	3	186	2	27486780
Pubmed	Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer.	LDHA SQSTM1	8.50e-05	3	186	2	32859246
Interaction	TOP3B interactions	VWA5B2 FRAS1 LZTR1 BICRA IARS1 MYOM3 RAP1GAP2 C15orf39 FAAP100 ITGB5 C8orf58 HIRA JAK3 NCOR2 PHLDB1 CELSR1 PELP1 SGSM2 PI4KA AHNAK ANKRD11 NAV1 NLRC5 COBL MICAL3 DDX20 HADHB TRAPPC9 DDX28 PRRC2B ARAP1	7.11e-06	1470	181	31	int:TOP3B
Interaction	YWHAH interactions	CASC3 ARHGAP32 FN1 EXPH5 CEP290 TNS2 PLEKHG2 SHKBP1 KSR1 PHLDB1 SQSTM1 PI4KA AHNAK KIAA1217 RABGAP1L MEPCE ANKRD11 NAV1 COBL RIMS2 UTRN TMCC1 TRAPPC9 MAST3 ANKS1A	1.85e-05	1102	181	25	int:YWHAH
Interaction	STAT5A interactions	FN1 PGR JAK3 NCOR2 SQSTM1 NFKB1 DDX20 AGAP2	2.45e-05	131	181	8	int:STAT5A
Interaction	NT5C interactions	ACTR8 TNS2 SHKBP1 AAAS ANKS1A	2.49e-05	39	181	5	int:NT5C
GeneFamily	PDZ domain containing	IL16 RGS3 LIMK1 PDLIM3 AHNAK DLG3 RIMS2 MAST3 PDZD2	9.63e-07	152	123	9	1220
GeneFamily	Ankyrin repeat domain containing	ANK3 ANKMY1 KIDINS220 EHMT2 NFKB1 ANKRD11 ARAP1 PPP1R27 AGAP2 ANKS1A	6.13e-06	242	123	10	403
GeneFamily	Fibronectin type III domain containing	FN1 TNC MYOM3 TNN EGFLAM MYBPC2	7.93e-04	160	123	6	555
GeneFamily	Fibronectin type III domain containing\|I-set domain containing\|Myosin binding proteins	MYOM3 MYBPC2	1.25e-03	8	123	2	658
GeneFamily	Complement system\|Sushi domain containing	CR1L ITGAM CFB	1.86e-03	36	123	3	492
GeneFamily	WD repeat domain containing	WDFY4 HIRA SHKBP1 AAAS CDC40 WDR11 BRWD1	2.11e-03	262	123	7	362
GeneFamily	DEAD-box helicases	DDX50 DDX20 DDX28	2.91e-03	42	123	3	499
Coexpression	GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	ATP6V1B2 IL16 CHD3 LDHA SLC27A1 HADHB ABCD2 PDGFC UTRN	1.33e-05	199	186	9	M6660
Coexpression	GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_UP	IL16 ISYNA1 MRPL4 SLC27A1 PRKAB1 FES PCSK7 MAST3 SMAD5	1.38e-05	200	186	9	M9615
Coexpression	NABA_CORE_MATRISOME	VWA5B2 FRAS1 COL11A1 COL19A1 FN1 TNC LAMA1 SSPOP TNN EGFLAM	2.48e-05	270	186	10	MM17057
Coexpression	NABA_CORE_MATRISOME	VWA5B2 FRAS1 COL11A1 COL19A1 FN1 TNC LAMA1 SSPOP TNN EGFLAM	2.90e-05	275	186	10	M5884
Coexpression	PEREZ_TP53_TARGETS	TRIM2 ANK3 SYNM MFSD9 ALDH1L1 ITGAM KSR1 KIAA1217 PRRT3 BRD7 KDM2B RIMBP2 MICAL3 EGFLAM ALDH4A1 TRAK2 MEGF11 ZNF367 PRRC2B ARAP1 SMAD5 BRWD1	4.61e-05	1201	186	22	M4391
Coexpression	GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TAN_DN	FN1 NAV1 PLD1	5.56e-05	11	186	3	M27966
Coexpression	FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_DN	EXPH5 NCOR2 SQSTM1 AHNAK SLC27A1 FES	6.43e-05	96	186	6	M11984
Coexpression	NABA_ECM_GLYCOPROTEINS	VWA5B2 FRAS1 FN1 TNC LAMA1 SSPOP TNN EGFLAM	6.94e-05	191	186	8	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	VWA5B2 FRAS1 FN1 TNC LAMA1 SSPOP TNN EGFLAM	8.31e-05	196	186	8	M3008
Coexpression	GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_DN	AEN ITGB5 JAK3 KSR1 PDLIM3 ALDH4A1 PLD1 PDZD2	8.92e-05	198	186	8	M5307
Coexpression	GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN	IL16 MAN2B2 ANK3 NAIP ITGAM RABGAP1L PDGFC MAST3	9.24e-05	199	186	8	M4620
Coexpression	GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN	HDAC9 ATP6V1B2 EXPH5 SIRT7 RGS3 CFB SQSTM1 PDE4DIP	9.57e-05	200	186	8	M4638
Coexpression	GSE22886_CTRL_VS_LPS_24H_DC_UP	IL16 ISYNA1 ACO2 ARFIP1 CDC40 NT5DC2 FES MAST3	9.57e-05	200	186	8	M4518
Coexpression	GSE27786_LIN_NEG_VS_BCELL_DN	CHD3 PLEKHG2 SQSTM1 RABGAP1L PDE4DIP ANKRD11 ZNF264 AGAP2	9.57e-05	200	186	8	M4768
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN	COL19A1 ACO2 NCOR2 CELSR1 FEZF1 NFKB1 ARMC5 PRRC2B	9.57e-05	200	186	8	M6583
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	ANK3 ACO2 MYOM3 RAP1GAP2 RGS3 PDLIM3 RABGAP1L PDE4DIP MICAL3	1.17e-07	191	186	9	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	FRAS1 COL19A1 ANK3 MYOM3 RGS3 RABGAP1L PDE4DIP MICAL3 PDZD2	1.34e-07	194	186	9	c3535f7cc0076653c72db582047cff053c322397
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 COL19A1 ANK3 RABGAP1L KIAA1328 FER TMCC1 TRAPPC9 PDZD2	1.59e-07	198	186	9	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 TRIM2 RBBP8 TTPA GRHL1 TMEM130 CELSR1 KIAA1217	1.02e-06	182	186	8	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FRAS1 FN1 TNC TNS2 ITGB5 RGS3 PGR ADAMTS14	1.30e-06	188	186	8	de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 COL11A1 EXPH5 LAMA1 MYOM3 RAP1GAP2 FZD6 RIMBP2	1.35e-06	189	186	8	5d9da836ce4308b8458bb3be3871a0aca734b6cd
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 TRIM2 ANK3 TTPA GRHL1 TMEM130 CELSR1 KIAA1217	1.46e-06	191	186	8	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	FRAS1 TRIM2 ANK3 TTPA GRHL1 TMEM130 CELSR1 KIAA1217	1.58e-06	193	186	8	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 TRIM2 ANK3 TTPA GRHL1 TMEM130 CELSR1 KIAA1217	1.70e-06	195	186	8	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 TRIM2 ANK3 B3GNT3 GRHL1 CELSR1 KIAA1217 RIMS2	1.70e-06	195	186	8	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGAP32 TRIM2 ANK3 TNC EXPH5 CELSR1 AHNAK KIAA1217	2.06e-06	200	186	8	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-Migrating_MyoFibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TNC ANKMY1 PHLDB1 PDLIM3 TNN ADAMTS14 POLK	4.09e-06	155	186	7	1882fa5fd25f77d6e3ac47b613f6fb3c67d8e50c
ToppCell	droplet-Spleen-SPLEEN-1m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 RAP1GAP2 ITGAM ITGB5 CAMKK2 FES TMCC1	6.95e-06	168	186	7	f3b7a7df54988de77dcc7066e2fc1feb9c280b13
ToppCell	droplet-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 RAP1GAP2 ITGAM ITGB5 FES ABCD2 TMCC1	7.22e-06	169	186	7	972618e684321060c7af2429f853a6d639e8aae8
ToppCell	droplet-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 RAP1GAP2 ITGAM ITGB5 FES ABCD2 TMCC1	7.22e-06	169	186	7	91cfff1ad559cc327c6bb71c98aa29f0b3642568
ToppCell	droplet-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 RAP1GAP2 ITGAM ITGB5 FES ABCD2 TMCC1	7.22e-06	169	186	7	8e5e513090e86ca29fb61dfd388014774c506914
ToppCell	Children_(3_yrs)-Immune-B_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 NLRC5 MICAL3	7.51e-06	170	186	7	e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell	368C-Myeloid-Macrophage-FABP4+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MAN2B2 ANK3 IARS1 ZNF805 POU2AF1 C8orf58 SCNN1D	7.80e-06	171	186	7	e59afa0a773dca3b9c208d17510ea55703b42598
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 LAMA1 RAP1GAP2 CELSR1 COBL RIMBP2 RIMS2	8.10e-06	172	186	7	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RBBP8 LAMA1 RAP1GAP2 CELSR1 COBL RIMBP2 RIMS2	8.10e-06	172	186	7	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HDAC9 TENT4A RAP1GAP2 WDFY4 PI4KA RABGAP1L ANKRD11	9.07e-06	175	186	7	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ZNF805 PGR C9orf43 NOP14 EGFLAM SHISA6	9.07e-06	175	186	7	12f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 ZNF805 PLEKHG2 GTDC1 DACH2 KIAA1217 EGFLAM	9.41e-06	176	186	7	a4d269075aa0efc46fa251b379f334e50c69391d
ToppCell	Club_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	TRIM2 CHD3 B3GNT3 CFB GRHL1 SGSM2 KIAA1217	9.41e-06	176	186	7	88c4ed0ab4a4ede8cad21385d799b723b5786cd9
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 ZNF805 PLEKHG2 GTDC1 DACH2 KIAA1217 EGFLAM	9.41e-06	176	186	7	cc6f65a7d2c622841c9d1ab3755586039d4ccc4d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 ZNF805 PLEKHG2 GTDC1 DACH2 KIAA1217 EGFLAM	9.41e-06	176	186	7	e9152defb4fd41267fb33c42c01fd0c683280783
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL11A1 ANK3 FBF1 LIMK1 CELSR1 SGSM2 MAST3	9.41e-06	176	186	7	792f414f5092aba14260b8e16378e793a822498e
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 RABGAP1L MICAL3	9.77e-06	177	186	7	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	FRAS1 TRIM2 TTPA GRHL1 TMEM130 CELSR1 KIAA1217	1.01e-05	178	186	7	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 TRIM2 ANK3 KSR1 GRHL1 SGSM2 KIAA1217	1.05e-05	179	186	7	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 POU2AF1 FCRLA RABGAP1L SLC28A2 TMCC1 MAST3	1.05e-05	179	186	7	f4fd214a9865c635d8a744ce5e0eff45174d3de4
ToppCell	facs-Kidney-nan-18m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC9 POU2AF1 FCRLA RABGAP1L SLC28A2 TMCC1 MAST3	1.05e-05	179	186	7	57d8d44a793314eec8f77030f4177bfe21d41652
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TNC MYOM3 ALDH1L1 TTPA KIAA1210 CELSR1	1.08e-05	119	186	6	79342c491a214c870ff6215da613db4a28c9d587
ToppCell	Hippocampus-Macroglia-ASTROCYTE\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TNC MYOM3 ALDH1L1 TTPA KIAA1210 CELSR1	1.08e-05	119	186	6	36857095d4e4cc6428d13bf7de04daec1f4cde1e
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B-B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 RABGAP1L MICAL3	1.13e-05	181	186	7	8d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell	nucseq-Immune-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 RABGAP1L MICAL3	1.26e-05	184	186	7	911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	FN1 RBBP8 PCDHAC1 B3GNT3 SQSTM1 AP5B1 RIMS2	1.26e-05	184	186	7	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	nucseq-Immune-Lymphocytic_B-Lymphocytic_B\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 RABGAP1L MICAL3	1.26e-05	184	186	7	942b58ae7172bb5f97e55b032db9329d161854af
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ANK3 MYOM3 RAP1GAP2 RGS3 PDLIM3 RABGAP1L PDE4DIP	1.44e-05	188	186	7	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 TRIM2 RBBP8 LAMA1 ALDH1L1 RIMBP2 MEGF11	1.44e-05	188	186	7	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 COL11A1 EXPH5 LAMA1 RAP1GAP2 FZD6 RIMBP2	1.55e-05	190	186	7	625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 TRIM2 TTPA GRHL1 TMEM130 CELSR1 KIAA1217	1.55e-05	190	186	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	VWA5B2 RAP1GAP2 DDN DACH2 RIMBP2 RIMS2 SRRM3	1.55e-05	190	186	7	5f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 TRIM2 RBBP8 RAP1GAP2 PDE4DIP RIMBP2 MEGF11	1.60e-05	191	186	7	5a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 TRIM2 RBBP8 RAP1GAP2 PDE4DIP RIMBP2 MEGF11	1.60e-05	191	186	7	55ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTNNAL1 TRIM2 LAMA1 RAP1GAP2 COBL RIMS2 MEGF11	1.60e-05	191	186	7	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CTNNAL1 TRIM2 LAMA1 RAP1GAP2 COBL RIMS2 MEGF11	1.60e-05	191	186	7	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	Healthy/Control-B_intermediate\|World / Disease group and Cell class	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 CELSR1 MICAL3	1.65e-05	192	186	7	2266aa695955f5d885708e6bc0d5a8827c306223
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 COL19A1 ANK3 RABGAP1L ANKRD11 TRAPPC9 PDZD2	1.65e-05	192	186	7	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL11A1 EXPH5 LAMA1 RAP1GAP2 FZD6 CELSR1 RIMBP2	1.65e-05	192	186	7	1aa5e4d9b32013a3f272561dcb8377f6805706df
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	HDAC9 COL19A1 POU2AF1 FCRLA WDFY4 FER MICAL3	1.71e-05	193	186	7	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	FRAS1 COL19A1 ANK3 RGS3 PDLIM3 RABGAP1L PDE4DIP	1.77e-05	194	186	7	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	COL19A1 ANK3 RABGAP1L KIAA1328 TMCC1 TRAPPC9 PDZD2	1.89e-05	196	186	7	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG\|World / Primary Cells by Cluster	COL11A1 LAMA1 ITGB5 CELSR1 PDLIM3 NT5DC2 AHNAK	1.95e-05	197	186	7	61749ccafeb938c310cff1de5ff924a1c794325a
ToppCell	Non-neuronal-Non-dividing-Radial_Glia-tRG-25\|World / Primary Cells by Cluster	COL11A1 LAMA1 ITGB5 CELSR1 PDLIM3 NT5DC2 AHNAK	1.95e-05	197	186	7	9d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 TRIM2 ANK3 B3GNT3 GRHL1 CELSR1 KIAA1217	2.02e-05	198	186	7	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 TRIM2 ANK3 B3GNT3 GRHL1 CELSR1 KIAA1217	2.02e-05	198	186	7	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	COL11A1 FN1 TNC CHD3 TNN KIAA1217 PDGFC	2.02e-05	198	186	7	196257c4420ac801ed9fbb444f11718adb7560ae
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	BCLAF1 EXPH5 CEP290 ANKRD11 TRAK2 UTRN SMAD5	2.02e-05	198	186	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 TRIM2 POU2AF1 GRHL1 TMEM130 KIAA1217 SHISA6	2.02e-05	198	186	7	fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 EXPH5 CELSR1 KIAA1217 COBL PDZD2	2.08e-05	199	186	7	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 EXPH5 CELSR1 KIAA1217 COBL PDZD2	2.08e-05	199	186	7	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	FRAS1 CTNNAL1 FZD6 KIDINS220 AHNAK KIAA1217 EGFLAM	2.08e-05	199	186	7	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FRAS1 COL11A1 ISYNA1 EXPH5 LAMA1 CELSR1 UTRN	2.08e-05	199	186	7	debdd7dba774d9ccff7effc3f4c132393d203dfa
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 BCKDHB RABGAP1L FER UTRN TRAPPC9	2.08e-05	199	186	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 RBKS CAMKK2 FES KDM2B TMCC1	2.13e-05	134	186	6	932b7dd5781b730dcd2ffe43f6e142e3f8630f67
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 NAIP RAP1GAP2 ITGAM WDFY4 KSR1 FES	2.15e-05	200	186	7	5432bdf495431cd26f6e4cd585100f3652588913
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 COL11A1 FN1 ALDH1L1 LDHA SGSM2 EGFLAM	2.15e-05	200	186	7	b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ANK3 RAP1GAP2 BCKDHB DACH2 KIAA1217 COBL	2.15e-05	200	186	7	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Macroglial-Glia_progenitor_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	AEN IARS1 LDHA BLVRB PDLIM3 SQSTM1 HADHB	2.15e-05	200	186	7	fc9e2094f4d22412e3dd79e79649a6d46d62caec
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 TBX19 PHLDB1 SLC16A2 NT5DC2 EGFLAM PDZD2	2.15e-05	200	186	7	4c3c11dd5e71ebc3d62264eeaeb71a850b149779
ToppCell	Bronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	IL16 COL11A1 FN1 ALDH1L1 LDHA SGSM2 EGFLAM	2.15e-05	200	186	7	7c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 SYNM TBX19 NT5DC2 EGFLAM SMAD5 PDZD2	2.15e-05	200	186	7	36de49593cf6ff1c9229fcceb150c1d68658a360
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGAP32 TRIM2 ANK3 EXPH5 CELSR1 AHNAK KIAA1217	2.15e-05	200	186	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 TRIM2 TNC GTDC1 FZD6 C9orf43 PDGFC	2.15e-05	200	186	7	a372ef3f9e6ff6e3c3376d6e10182977c5067788
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TMPPE HDAC9 ITGAM PDGFC CEACAM20 AGAP2	2.42e-05	137	186	6	ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TMPPE HDAC9 ITGAM PDGFC CEACAM20 AGAP2	2.42e-05	137	186	6	47859aa25f32367461c1ec75ed9060bee430c6b7
ToppCell	facs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDN ANKMY1 FCRLA ITGAM C9orf43 FES	3.20e-05	144	186	6	8bd042f12186f36bc5aabf6a0232270a448f4b58
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-13\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL19A1 DDN POU2AF1 FCRLA WDFY4 MICAL3	3.20e-05	144	186	6	b2a9f3b5dd46d27689467f4a5fd717cd5827821f
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	POU2AF1 B3GNT3 CFB SLC28A2 NLRC5	3.21e-05	87	186	5	4274e04fa4aca85c2cefd8c5e03d0fa4a4f15536
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	POU2AF1 B3GNT3 CFB SLC28A2 NLRC5	3.21e-05	87	186	5	8b1a0bd5d6af32afaca19e9c69f86530bbaa309d
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Vwf_(Vwf)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	POU2AF1 B3GNT3 CFB SLC28A2 NLRC5	3.21e-05	87	186	5	cc89f4176b70d4eb5b5bf0ff2319b5f1f9e292c0
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	POU2AF1 B3GNT3 CFB SLC28A2 NLRC5	3.21e-05	87	186	5	54cbdf80aae3595eaace20c7cbac763282558213
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PCDHAC1 TNS2 SPTBN5 NAV1 RIMBP2 MEGF11	4.83e-05	155	186	6	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LZTR1 POU2AF1 CHD3 JAK3 NLRC5 TRAPPC9	5.00e-05	156	186	6	fbe23876f0899853cea3c5c4f3044a9cea064d5b
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC RAP1GAP2 ITGAM TNN CACNA1G KLKB1	6.17e-05	162	186	6	71d7849108a1b59beff40e46000172c45a2f5439
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 SYNM PLEKHG2 NT5DC2 EGFLAM ODAD3	6.17e-05	162	186	6	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 SYNM PLEKHG2 NT5DC2 EGFLAM ODAD3	6.17e-05	162	186	6	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 SYNM PLEKHG2 NT5DC2 EGFLAM ODAD3	6.17e-05	162	186	6	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-Pre-B\|bone_marrow / Manually curated celltypes from each tissue	TMPRSS9 MFSD9 POU2AF1 FCRLA NAV1 MYBPC2	6.17e-05	162	186	6	e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 FN1 SYNM BCKDHB PLD1 DDX28	6.61e-05	164	186	6	43630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 FN1 SYNM BCKDHB PLD1 DDX28	6.61e-05	164	186	6	108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ISYNA1 FN1 SYNM BCKDHB PLD1 DDX28	6.61e-05	164	186	6	46208f18325976c89f572f6627aea0582142b92d
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB5 BLVRB SLC27A1 PDGFC RIMS2 ODAD3	6.83e-05	165	186	6	6dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCell	facs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 MYOM3 POU2AF1 FCRLA CFB AHNAK	6.83e-05	165	186	6	ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KSR1 AAAS DACH2 CEP72 UTRN MEGF11	7.06e-05	166	186	6	3b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EXPH5 RAP1GAP2 ALDH1L1 GRHL1 COBL MAST3	7.30e-05	167	186	6	f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive\|lymph-node_spleen / Manually curated celltypes from each tissue	HDAC9 FCRLA WDFY4 PGR COBL MICAL3	7.55e-05	168	186	6	494d5a11154ff22fedb25f4036d730cef376da60
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-mLTo\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ISYNA1 ANK3 TNC PDLIM3 RIMBP2 EGFLAM	7.80e-05	169	186	6	559e98216720e4babf0b0941100f1b485c35b11b
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 TBX19 NT5DC2 EGFLAM SHISA6 ZNF367	8.06e-05	170	186	6	e20568c8f3f17d94de78229617eb2f7e4c5af2bc
Computational	Genes in the cancer module 272.	ALDH1L1 BLVRB ALDH4A1	1.77e-04	12	103	3	MODULE_272
Computational	Genes in the cancer module 412.	TNC ITGAM ITGB5	2.28e-04	13	103	3	MODULE_412
Computational	Genes in the cancer module 248.	IL16 COL11A1 JAK3 PDLIM3 FER FES DLG3	2.32e-04	129	103	7	MODULE_248
Drug	Thiorphan [76721-89-6]; Down 200; 15.8uM; MCF7; HT_HG-U133A	AEN ARHGAP32 LZTR1 TEDC2 HIRA KIDINS220 CEP72 SGSM2 RABGAP1L PCSK7 TMCC1 SMAD5 ANKS1A	9.15e-09	199	184	13	6249_DN
Drug	benz(a)anthracene	AEN FRAS1 LZTR1 TRIM2 ANK3 TNC BCLAF1 RBPJL LAMA1 MYOM3 POU2AF1 ALDH1L1 FCRLA RGS3 CFB PGR FZD6 JAK3 AAAS CDC40 NT5DC2 AHNAK NLRC5 COBL SERPINA10 ADAMTS14 POLK UTRN ZNF367 BRWD1	8.45e-08	1251	184	30	ctd:C030935
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	AEN ACTR8 GTDC1 FAAP100 HIRA KIDINS220 SQSTM1 DLG3 ALDH4A1 TRAPPC9 SMAD5	6.02e-07	196	184	11	987_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HG-U133A	AEN FN1 BICRA TEDC2 TNS2 RGS3 PCSK7 DLG3 TRAPPC9 DDX28 MAST3	6.66e-07	198	184	11	421_DN
Drug	Cefazolin sodium salt [27164-46-1]; Up 200; 8.4uM; HL60; HT_HG-U133A	EXPH5 TEDC2 RAP1GAP2 ANKMY1 ALDH1L1 FZD6 LIMK1 CAMKK2 RIMS2 DDX28	4.86e-06	197	184	10	2564_UP
Drug	Chloramphenicol [56-75-7]; Down 200; 12.4uM; PC3; HT_HG-U133A	ISYNA1 BICRA TEDC2 MFSD9 RGS3 SUPT5H SGSM2 ANKRD11 DDX28 ARAP1	4.86e-06	197	184	10	1795_DN
Drug	Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; MCF7; HT_HG-U133A	LZTR1 TRIM2 CEP290 MFSD9 CHD3 PDE4DIP PCSK7 MICAL3 UTRN MAST3	5.08e-06	198	184	10	7013_UP
Drug	Pyrilamine maleate [59-33-6]; Down 200; 10uM; PC3; HT_HG-U133A	AEN BICRA ANKMY1 FAAP100 HIRA AAAS PCSK7 DLG3 TMCC1 PRRC2B	5.08e-06	198	184	10	5869_DN
Drug	Perhexiline maleate [6724-53-4]; Down 200; 10.2uM; MCF7; HT_HG-U133A	ACTR8 LZTR1 ANK3 TEDC2 C15orf39 FAAP100 PHLDB1 TMCC1 TRAPPC9 PRRC2B	5.08e-06	198	184	10	5501_DN
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; PC3; HT_HG-U133A	TRIM2 MAN2B2 TNS2 HIRA CELSR1 AAAS SGSM2 PRKAB1 DLG3 DDX28	5.31e-06	199	184	10	7258_DN
Drug	Oxethazaine [126-27-2]; Down 200; 8.6uM; MCF7; HT_HG-U133A	CEP290 CHD3 PHLDB1 PDE4DIP ALDH4A1 UTRN TRAPPC9 DDX28 ARAP1 SMAD5	5.31e-06	199	184	10	1484_DN
Drug	A-FN	FN1 SIRT7 ITGAM ALDH4A1	1.46e-05	19	184	4	CID005287635
Drug	sodium succinate	ACO2 KLKB1 UTRN	2.82e-05	8	184	3	CID000009020
Drug	Lovastatin [75330-75-5]; Up 200; 9.8uM; HL60; HT_HG-U133A	ACTR8 TNC BCKDHB JAK3 KSR1 PHLDB1 RIMBP2 CACNA1G ALDH4A1	3.23e-05	196	184	9	2494_UP
Drug	Isoconazole [27523-40-6]; Up 200; 9.6uM; PC3; HT_HG-U133A	ANK3 CEP290 BCKDHB GTDC1 CEP72 SQSTM1 RABGAP1L PDE4DIP SMAD5	3.23e-05	196	184	9	2056_UP
Drug	Mebeverine hydrochloride [2753-45-9]; Down 200; 8.6uM; PC3; HT_HG-U133A	LZTR1 FN1 ANK3 BICRA RBKS HIRA TBX19 PCSK7 PRRC2B	3.23e-05	196	184	9	7147_DN
Drug	aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A	LZTR1 MFSD9 BCKDHB ITGB5 JAK3 CEP72 RABGAP1L RIMS2 ARAP1	3.36e-05	197	184	9	1629_UP
Drug	Naproxen [22204-53-1]; Down 200; 17.4uM; PC3; HT_HG-U133A	ACTR8 LZTR1 DDN HIRA SQSTM1 SGSM2 FER PRRC2B BRWD1	3.36e-05	197	184	9	6358_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	TRIM2 FN1 CEP290 C15orf39 ANKMY1 CHD3 SQSTM1 UTRN TRAPPC9	3.36e-05	197	184	9	1496_DN
Drug	17-DMAG; Down 200; 0.1uM; HL60; HT_HG-U133A	LZTR1 FN1 C15orf39 FAAP100 BLVRB UTRN TMCC1 TRAPPC9 ARAP1	3.36e-05	197	184	9	1154_DN
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	FN1 RGS3 LIMK1 RABGAP1L PDE4DIP PCSK7 ALDH4A1 RIMS2 ARAP1	3.50e-05	198	184	9	6096_DN
Drug	Acetazolamide [59-66-5]; Up 200; 18uM; HL60; HT_HG-U133A	FN1 ANK3 BICRA DDN RGS3 SQSTM1 PDE4DIP TMCC1 PRRC2B	3.50e-05	198	184	9	1850_UP
Drug	Betahistine mesylate [54856-23-4]; Up 200; 17.2uM; HL60; HT_HG-U133A	ACTR8 FN1 DDN SPTBN5 JAK3 PHLDB1 ALDH4A1 RIMS2 SMAD5	3.50e-05	198	184	9	2472_UP
Drug	Adrenosterone [382-45-6]; Down 200; 13.4uM; HL60; HT_HG-U133A	AEN LZTR1 ANK3 EXPH5 BCKDHB FAAP100 FES MICAL3 PLD1	3.50e-05	198	184	9	3107_DN
Drug	Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A	TRIM2 C15orf39 TNS2 BCKDHB CHD3 HIRA PDE4DIP ANKRD11 SMAD5	3.50e-05	198	184	9	1690_DN
Drug	Azathioprine [446-86-6]; Down 200; 14.4uM; MCF7; HT_HG-U133A	CEP290 TNS2 ANKMY1 BCKDHB RGS3 TBX19 PDE4DIP FER DLG3	3.64e-05	199	184	9	1528_DN
Drug	valdecoxib; Up 200; 10uM; PC3; HT_HG-U133A	CEP290 CHD3 RGS3 SPTBN5 TBX19 LIMK1 COBL UTRN PRRC2B	3.78e-05	200	184	9	6408_UP
Drug	chrysene	AEN ANK3 TNC BCLAF1 LAMA1 MYOM3 SCYL1 POU2AF1 BCKDHB CFB AAAS NT5DC2 AHNAK BRD7 COBL ADAMTS14 POLK UTRN ZNF367	8.64e-05	871	184	19	ctd:C031180
Drug	Cycloheximide [66-81-9]; Down 200; 14.2uM; PC3; HT_HG-U133A	TRIM2 MFSD9 GTDC1 RGS3 HIRA TRAK2 SMAD5 PDZD2	1.16e-04	181	184	8	5743_DN
Drug	alpha-CaM	CTNNAL1 FN1 TNC DDN CAMKK2	1.45e-04	62	184	5	CID000196705
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ARHGAP32 CEP290 CHD3 ANKRD11 ALDH4A1 TMCC1 ANKS1A BRWD1	1.51e-04	188	184	8	4845_DN
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	ACTR8 MFSD9 CHD3 AHNAK MICAL3 MAST3 SMAD5 BRWD1	1.68e-04	191	184	8	4168_DN
Drug	Albendazole [54965-21-8]; Down 200; 15uM; MCF7; HT_HG-U133A	LZTR1 SYNM RBKS RGS3 HIRA RABGAP1L PDE4DIP ARAP1	1.74e-04	192	184	8	3164_DN
Drug	Methantheline bromide [53-46-3]; Down 200; 9.6uM; MCF7; HT_HG-U133A	LZTR1 TRIM2 FN1 ANKMY1 HIRA KIDINS220 CEP72 PCSK7	1.74e-04	192	184	8	6254_DN
Drug	Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; HL60; HT_HG-U133A	TRIM2 COL19A1 ANK3 KSR1 NCOR2 PDLIM3 SLC16A2 RIMS2	1.74e-04	192	184	8	2738_UP
Drug	progesterone acetate	FN1 TNC PGR	1.77e-04	14	184	3	CID000134580
Drug	geldanamycin; Down 200; 1uM; PC3; HT_HG-U133A	AEN ISYNA1 TEDC2 SQSTM1 PCSK7 COBL DLG3 PRRC2B	1.81e-04	193	184	8	1228_DN
Drug	Althiazide [5588-16-9]; Up 200; 10.4uM; HL60; HT_HG-U133A	TRIM2 SPTBN5 SLC16A2 TNN CACNA1G KLKB1 TMCC1 DDX28	1.87e-04	194	184	8	2527_UP
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A	HDAC9 AEN EXPH5 BICRA RAP1GAP2 DDN CEP72 PLD1	1.87e-04	194	184	8	2485_DN
Drug	Midodrine hydrochloride [3092-17-9]; Down 200; 13.8uM; PC3; HT_HG-U133A	ARHGAP32 TRIM2 C15orf39 TNS2 HIRA PRKAB1 DLG3 BRWD1	1.87e-04	194	184	8	2087_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A	ARHGAP32 C15orf39 RBKS HIRA CEP72 DLG3 PRRC2B MAST3	1.87e-04	194	184	8	1217_DN
Drug	Butirosin disulfate salt [51022-98-1]; Down 200; 5.4uM; MCF7; HT_HG-U133A	TRIM2 TNS2 ANKMY1 CHD3 PDE4DIP MICAL3 TRAPPC9 MAST3	1.87e-04	194	184	8	6779_DN
Drug	Artemisinin [63968-64-9]; Up 200; 14.2uM; PC3; HT_HG-U133A	TRIM2 FN1 ANKMY1 FAAP100 LIMK1 PDE4DIP MICAL3 TMCC1	1.87e-04	194	184	8	7247_UP
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	AEN TRIM2 TEDC2 BCKDHB GTDC1 CEP72 MAST3 SMAD5	1.87e-04	194	184	8	6958_DN
Drug	Tropine [120-29-6]; Up 200; 28.4uM; HL60; HT_HG-U133A	SGSM2 AHNAK FER CACNA1G RIMS2 TMCC1 DDX28 AGAP2	1.94e-04	195	184	8	6147_UP
Drug	Isoniazid [54-85-3]; Down 200; 29.2uM; PC3; HT_HG-U133A	ARHGAP32 TEDC2 DDN C15orf39 RBKS KIDINS220 SQSTM1 TRAPPC9	1.94e-04	195	184	8	5840_DN
Drug	Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; PC3; HT_HG-U133A	PDSS2 TRIM2 CEP290 C15orf39 ARFIP1 HIRA KIDINS220 COBL	1.94e-04	195	184	8	1831_UP
Drug	Methazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A	IL16 EXPH5 ALDH1L1 PDE4DIP PLD1 UTRN TMCC1 TRAPPC9	1.94e-04	195	184	8	6268_UP
Drug	Nystatine [1400-61-9]; Up 200; 4.4uM; HL60; HT_HG-U133A	TNC JAK3 LIMK1 PHLDB1 CAMKK2 PDE4DIP FER ALDH4A1	1.94e-04	195	184	8	2500_UP
Drug	Imipramine hydrochloride [113-52-0]; Up 200; 12.6uM; HL60; HT_HG-U133A	AEN TEDC2 TNS2 BCKDHB TBX19 PLD1 UTRN SMAD5	2.01e-04	196	184	8	1849_UP
Drug	Quinic acid [86-68-0]; Down 200; 19.6uM; HL60; HT_HG-U133A	FN1 EXPH5 RBKS BCKDHB ITGAM SQSTM1 AHNAK PDE4DIP	2.01e-04	196	184	8	2978_DN
Drug	Lactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A	FN1 TNC KIDINS220 SGSM2 RABGAP1L ALDH4A1 PLD1 TMCC1	2.01e-04	196	184	8	6605_DN
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; PC3; HT_HG-U133A	BICRA ANKMY1 GTDC1 PDE4DIP DLG3 UTRN TMCC1 SMAD5	2.01e-04	196	184	8	4645_DN
Drug	Alprenolol hydrochloride [13707-88-5]; Down 200; 14uM; PC3; HT_HG-U133A	MAN2B2 BICRA RGS3 TBX19 SQSTM1 FER MAST3 BRWD1	2.01e-04	196	184	8	7141_DN
Drug	Lovastatin [75330-75-5]; Up 200; 9.8uM; PC3; HT_HG-U133A	FN1 B3GNT3 JAK3 PHLDB1 TNN COBL DLG3 RIMS2	2.01e-04	196	184	8	6633_UP
Drug	Retinoic acid [302-79-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	B3GNT3 SGSM2 PDE4DIP DLG3 ALDH4A1 UTRN TMCC1 DDX28	2.01e-04	196	184	8	5767_DN
Drug	Alcuronium chloride [15180-03-7]; Up 200; 5.4uM; MCF7; HT_HG-U133A	HDAC9 BCKDHB ITGB5 NCOR2 PHLDB1 CAMKK2 PDE4DIP FER	2.01e-04	196	184	8	7345_UP
Drug	Syrosingopine [84-36-6]; Down 200; 6uM; PC3; HT_HG-U133A	SYNM HIRA PDE4DIP MEPCE COBL ALDH4A1 DDX28 ARAP1	2.01e-04	196	184	8	5733_DN
Drug	Acetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT_HG-U133A	ACTR8 TEDC2 C15orf39 TNS2 BCKDHB CHD3 HIRA PRRC2B	2.01e-04	196	184	8	1686_DN
Drug	Demecarium bromide [56-94-0]; Down 200; 5.6uM; PC3; HT_HG-U133A	TEDC2 ANKMY1 FAAP100 HIRA COBL DLG3 ALDH4A1 UTRN	2.01e-04	196	184	8	5795_DN
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	EXPH5 BICRA TEDC2 FAAP100 TBX19 SGSM2 PDE4DIP FER	2.01e-04	196	184	8	2974_DN
Drug	Yohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A	ARHGAP32 MAN2B2 CEP290 RAP1GAP2 RABGAP1L DLG3 PRRC2B BRWD1	2.08e-04	197	184	8	7130_DN
Drug	estradiol, USP; Down 200; 0.1uM; HL60; HT_HG-U133A	AEN ANK3 TNS2 KIDINS220 SGSM2 AHNAK CACNA1G TRAPPC9	2.08e-04	197	184	8	2668_DN
Drug	Enalapril maleate [76095-16-4]; Up 200; 8.2uM; MCF7; HT_HG-U133A	LZTR1 B3GNT3 TBX19 PHLDB1 ALDH4A1 RIMS2 UTRN ARAP1	2.08e-04	197	184	8	7026_UP
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	FN1 C15orf39 GTDC1 RGS3 PHLDB1 PDE4DIP PRRC2B ARAP1	2.08e-04	197	184	8	5025_DN
Drug	Ifenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ACTR8 ANK3 PHLDB1 SQSTM1 PDE4DIP TMCC1 DDX28 SMAD5	2.08e-04	197	184	8	5463_DN
Drug	Meglumine [6284-40-8]; Up 200; 20.4uM; MCF7; HT_HG-U133A	TRIM2 ANKMY1 BCKDHB GTDC1 CEP72 RABGAP1L PDE4DIP AGAP2	2.08e-04	197	184	8	5285_UP
Drug	Bisacodyl [603-50-9]; Up 200; 11uM; HL60; HT_HG-U133A	TRIM2 ANK3 TNC PDLIM3 TNN DLG3 ALDH4A1 SMAD5	2.08e-04	197	184	8	2435_UP
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; HL60; HT_HG-U133A	BICRA DDN PLPPR3 FZD6 AHNAK RABGAP1L PDE4DIP TMCC1	2.08e-04	197	184	8	2903_DN
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A	AEN ARHGAP32 TNS2 BCKDHB CELSR1 RABGAP1L PCSK7 MAST3	2.08e-04	197	184	8	6935_DN
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A	TRIM2 ANKMY1 HIRA SGSM2 ALDH4A1 TMCC1 ARAP1 BRWD1	2.08e-04	197	184	8	5835_UP
Drug	Moxisylyte hydrochoride [964-52-3]; Down 200; 12.6uM; HL60; HT_HG-U133A	ACTR8 TEDC2 CHD3 GTDC1 ARFIP1 TBX19 SGSM2 PRKAB1	2.08e-04	197	184	8	1846_DN
Drug	(+,-)-Synephrine [94-07-5]; Down 200; 24uM; PC3; HT_HG-U133A	TRIM2 MAN2B2 TEDC2 AAAS CDC40 MAST3 SMAD5 BRWD1	2.08e-04	197	184	8	7150_DN
Drug	Mephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A	ACTR8 C15orf39 PDE4DIP FER PCSK7 DLG3 PRRC2B BRWD1	2.08e-04	197	184	8	7374_DN
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	FRAS1 KSR1 NCOR2 LIMK1 PHLDB1 KIDINS220 PDLIM3 DDX28	2.08e-04	197	184	8	5207_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A	TRIM2 FN1 BCKDHB RGS3 KSR1 NCOR2 FER AGAP2	2.08e-04	197	184	8	6497_UP
Drug	Benfotiamine [22457-89-2]; Up 200; 8.6uM; HL60; HT_HG-U133A	FRAS1 ANK3 ITGB5 PDLIM3 PDE4DIP PLD1 TRAPPC9 AGAP2	2.08e-04	197	184	8	2177_UP
Drug	Doxycycline hydrochloride [10592-13-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	ANK3 BICRA TEDC2 MFSD9 RBKS SLC16A2 PCSK7 MAST3	2.08e-04	197	184	8	7195_DN
Drug	(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Down 200; 11uM; PC3; HT_HG-U133A	ISYNA1 TRIM2 TEDC2 ITGB5 KIDINS220 PDE4DIP PLD1 TMCC1	2.08e-04	197	184	8	6663_DN
Drug	Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; PC3; HT_HG-U133A	LZTR1 C15orf39 HIRA KIDINS220 SGSM2 PCSK7 DLG3 MAST3	2.08e-04	197	184	8	6360_DN
Drug	Chlorphensin carbamate [886-74-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	SYNM CEP290 C15orf39 RBKS BCKDHB KIDINS220 CEP72 PCSK7	2.08e-04	197	184	8	7472_DN
Drug	Fenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A	FN1 EXPH5 ALDH1L1 PHLDB1 PDLIM3 RIMS2 UTRN PDZD2	2.15e-04	198	184	8	6001_UP
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Down 200; 15.8uM; MCF7; HT_HG-U133A	ACTR8 C15orf39 RGS3 HIRA PCSK7 COBL ALDH4A1 AGAP2	2.15e-04	198	184	8	2633_DN
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; HL60; HT_HG-U133A	PDSS2 EXPH5 BCKDHB ITGB5 MRPL4 CELSR1 SUPT5H TMCC1	2.15e-04	198	184	8	1300_UP
Drug	Oxprenolol hydrochloride [6452-73-9]; Down 200; 13.2uM; PC3; HT_HG-U133A	BICRA RBKS ANKMY1 GTDC1 FAAP100 AAAS DLG3 TMCC1	2.15e-04	198	184	8	5871_DN
Drug	Practolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A	TRIM2 DDN PDLIM3 FES CACNA1G SERPINA10 PLD1 AGAP2	2.15e-04	198	184	8	4603_UP
Drug	Pizotifen malate [5189-11-7]; Up 200; 9.4uM; HL60; HT_HG-U133A	ACTR8 FN1 ANK3 ALDH1L1 B3GNT3 NCOR2 PDE4DIP ALDH4A1	2.15e-04	198	184	8	3134_UP
Drug	raloxifene hydrochloride; Down 200; 0.1uM; MCF7; HG-U133A	AEN B3GNT3 NCOR2 LIMK1 PHLDB1 COBL DLG3 TMCC1	2.15e-04	198	184	8	202_DN
Drug	Butamben [94-25-7]; Up 200; 20.6uM; HL60; HT_HG-U133A	AEN MFSD9 ITGB5 AHNAK FER ALDH4A1 PLD1 SMAD5	2.15e-04	198	184	8	2531_UP
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A	FRAS1 TRIM2 FN1 RGS3 SPTBN5 KSR1 RIMS2 ARAP1	2.15e-04	198	184	8	3324_UP
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	ACTR8 MFSD9 ANKMY1 TBX19 PDE4DIP UTRN TMCC1 SMAD5	2.15e-04	198	184	8	6041_DN
Drug	probucol; Down 200; 10uM; MCF7; HG-U133A	IL16 VRK3 TEDC2 TNS2 PHLDB1 AAAS COBL ALDH4A1	2.15e-04	198	184	8	592_DN
Drug	Guanethidine sulfate [60-02-6]; Down 200; 13.4uM; PC3; HT_HG-U133A	AEN ACTR8 FN1 RGS3 LIMK1 AAAS SGSM2 BRWD1	2.15e-04	198	184	8	5731_DN
Drug	Troleandomycin [2751-09-9]; Up 200; 5uM; HL60; HG-U133A	LZTR1 RBKS CHD3 AAAS AHNAK PCSK7 TRAPPC9 SMAD5	2.15e-04	198	184	8	1965_UP
Drug	Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; PC3; HT_HG-U133A	ISYNA1 MFSD9 PHLDB1 SGSM2 PDE4DIP PRKAB1 FER ALDH4A1	2.15e-04	198	184	8	7130_UP
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; HL60; HT_HG-U133A	AEN COL19A1 ANKMY1 AHNAK PDE4DIP PLD1 DDX28 AGAP2	2.15e-04	198	184	8	2197_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; MCF7; HT_HG-U133A	RBKS KIDINS220 PCSK7 DLG3 TRAPPC9 DDX28 PRRC2B ARAP1	2.15e-04	198	184	8	6228_DN
Drug	Nomegestrol acetate [58652-20-3]; Down 200; 10.8uM; PC3; HT_HG-U133A	ISYNA1 LZTR1 ITGB5 CEP72 PCSK7 UTRN TMCC1 DDX28	2.15e-04	198	184	8	6362_DN
Drug	Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	ARHGAP32 HIRA PHLDB1 SUPT5H SGSM2 DLG3 DDX28 PDZD2	2.15e-04	198	184	8	7303_DN
Drug	rotenone; Down 200; 1uM; MCF7; HT_HG-U133A	AEN C15orf39 ANKMY1 PGR NCOR2 RABGAP1L MAST3 ARAP1	2.15e-04	198	184	8	5915_DN
Disease	severe acute respiratory syndrome, COVID-19	RAP1GAP2 BCKDHB WDFY4 KSR1 DACH2 KIAA1217 PDE4DIP FER RIMBP2 DHRSX MEGF11 PDZD2	2.24e-05	447	181	12	EFO_0000694, MONDO_0100096
Disease	membranoproliferative glomerulonephritis (is_implicated_in)	FN1 CFB	3.74e-05	2	181	2	DOID:2920 (is_implicated_in)
Disease	multiple sclerosis	TRIM2 TENT4A POU2AF1 ALDH1L1 FCRLA GTDC1 CR1L NCOR2 PHLDB1 SGSM2 NFKB1 NLRC5 AGAP2	8.31e-05	594	181	13	MONDO_0005301
Disease	urate measurement, bone density	FRAS1 RAP1GAP2 CFB KIDINS220 EHMT2 FEZF1 RABGAP1L ANKRD11 NAV1 UTRN MEGF11 PRRC2B PDZD2	1.25e-04	619	181	13	EFO_0003923, EFO_0004531
Disease	oral microbiome measurement	HDAC9 FRAS1 KIAA1217 PDZD2	1.28e-04	42	181	4	EFO_0801229
Disease	mean platelet volume	HDAC9 ARHGAP32 PCDHGA4 ANKMY1 ARFIP1 RGS3 SHKBP1 C9orf43 PI4KA ANKRD11 DLG3 HADHB SRRM3 ZNF367 ARAP1 SMAD5 ANKS1A	1.93e-04	1020	181	17	EFO_0004584
Disease	Osteoarthritis of hip	HDAC9 COL11A1 TNC	2.40e-04	20	181	3	C0029410
Disease	coronary atherosclerosis measurement	HDAC9 NAV1	3.70e-04	5	181	2	EFO_0007938
Disease	inflammatory bowel disease (implicated_via_orthology)	IL16 KLKB1 PDZD2	4.73e-04	25	181	3	DOID:0050589 (implicated_via_orthology)
Disease	abdominal aortic artery calcification	HDAC9 NAV1	7.70e-04	7	181	2	EFO_0004859
Disease	non-small cell lung carcinoma	LAMA1 PHLDB1 HADHB ANKS1A	1.19e-03	75	181	4	EFO_0003060
Disease	primary biliary cirrhosis	IL16 POU2AF1 WDFY4 NFKB1 MAST3	1.40e-03	133	181	5	EFO_1001486
Disease	cortical thickness	VWA5B2 HDAC9 COL11A1 LAMA1 ITGB5 MAD2L1BP PHLDB1 CELSR1 NT5DC2 PI4KA NFKB1 NAV1 MICAL3 PDGFC PDZD2 ANKS1A	1.44e-03	1113	181	16	EFO_0004840
Disease	eotaxin measurement	CCDC13 MICAL3 SRRM3 PDZD2	1.51e-03	80	181	4	EFO_0008122
Disease	bone morphogenetic protein 7 measurement	KLKB1 ZNF367	1.63e-03	10	181	2	EFO_0020187
Disease	HYPOGONADOTROPIC HYPOGONADISM 7 WITH OR WITHOUT ANOSMIA	WDR11 FEZF1	1.98e-03	11	181	2	146110
Disease	Hypogonadotropic hypogonadism 7 with or without anosmia	WDR11 FEZF1	1.98e-03	11	181	2	cv:C0342384
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	ANK3 SHKBP1	1.98e-03	11	181	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	stroke	HDAC9 RAP1GAP2 CHD3 WDFY4 SHISA6	1.99e-03	144	181	5	EFO_0000712
Disease	response to methotrexate, serum alanine aminotransferase measurement	RAP1GAP2 TRAPPC9 PDZD2	2.34e-03	43	181	3	EFO_0004735, GO_0031427
Disease	pulse pressure measurement	HDAC9 COL11A1 FN1 PCDHAC1 CR1L SSPOP ITGB5 CFB MRPL4 LIMK1 KIAA1217 FER FES ANKRD11 NAV1 LINC02694 PDGFC TRAPPC9	2.36e-03	1392	181	18	EFO_0005763
Disease	Leber congenital amaurosis (implicated_via_orthology)	CEP290 DHRSX	2.79e-03	13	181	2	DOID:14791 (implicated_via_orthology)
Disease	chromosome 22q11.2 deletion syndrome, distal (implicated_via_orthology)	HIRA PI4KA	3.24e-03	14	181	2	DOID:0060413 (implicated_via_orthology)
Disease	Schizophrenia	HDAC9 ARHGAP32 ANK3 LAMA1 ITGAM CAMKK2 WDR11 PI4KA NAV1 KDM2B DLG3 RIMS2 SMAD5	3.26e-03	883	181	13	C0036341
Disease	apolipoprotein B to apolipoprotein A1 ratio	NLRC5 PCSK7 CEACAM20	3.40e-03	49	181	3	EFO_0021897
Disease	idiopathic scoliosis (implicated_via_orthology)	SSPOP ODAD3	4.24e-03	16	181	2	DOID:0060250 (implicated_via_orthology)
Disease	Small cell carcinoma of lung	BCLAF1 FER RIMS2	4.48e-03	54	181	3	C0149925
Disease	eosinophil count	TENT4A RBBP8 ACO2 RAP1GAP2 POU2AF1 PLPPR3 NCOR2 CCDC13 CELSR1 PELP1 SUPT5H NFKB1 ANKRD11 NLRC5 PLD1 LINC02694 SRRM3 MAST3	4.74e-03	1488	181	18	EFO_0004842
Disease	estradiol measurement	RBBP8 CELSR1 EHMT2 NAV1	4.77e-03	110	181	4	EFO_0004697
Disease	lupus nephritis (is_implicated_in)	ITGAM KLKB1	5.37e-03	18	181	2	DOID:0080162 (is_implicated_in)
Disease	Idiopathic hypogonadotropic hypogonadism	WDR11 FEZF1	5.37e-03	18	181	2	C0342384
Disease	spine bone size	COL11A1 BCKDHB	5.37e-03	18	181	2	EFO_0004508
Disease	glomerulonephritis (is_marker_for)	FN1 KLKB1	5.97e-03	19	181	2	DOID:2921 (is_marker_for)
Disease	polycystic kidney disease (biomarker_via_orthology)	TNC CFB	5.97e-03	19	181	2	DOID:0080322 (biomarker_via_orthology)
Disease	cholesterol to total lipids in IDL percentage	TENT4A PCSK7 POLK	6.01e-03	60	181	3	EFO_0022233

Protein segments in the cluster

Peptide	Gene	Start	Entry
GAGLTRLPIEDHKRF	NAIP	106	Q13075
LEPRHLGGRAIITKS	ACO2	676	Q99798
LSEPGLHTRARVSLK	AEN	221	Q8WTP8
KTPGRLDHGTRTAFI	AAAS	56	Q9NRG9
GKGRLSSPRHVTTLS	EGFLAM	121	Q63HQ2
GTGEKLRLSAHTILP	ANKRD11	421	Q6UB99
DKHLEPLKSLGGRTS	RBBP8	431	Q99708
AKGAGISLLSITHRP	ABCD2	651	Q9UBJ2
ERRKPDGTTTLGLLH	BRD7	341	Q9NPI1
IHPGSTTLRIGRATD	ACTR8	51	Q9H981
HGRSRELAKPSIAVS	CEACAM20	61	Q6UY09
TLDGRGPSRVISKHD	BLVRB	166	P30043
RDLKHSLPSGLGLSE	ARFIP1	31	P53367
SGKRLPRILEASSRH	C17orf100	56	A8MU93
HARSSPSLTILAGGK	ALDH4A1	406	P30038
TVGLKLHRKGDRSPE	AHNAK	81	Q09666
AGLSTPGSLHRAAKR	AGAP2	631	Q99490
LVSLASHPKRAVREG	ARMC5	286	Q96C12
DLRGGRILLGHATKS	EHMT2	101	Q96KQ7
LSGQHRSLRLASKPE	C8orf58	131	Q8NAV2
ARTGHLPAVEKLLSG	ANKS1A	11	Q92625
SEEAVRAKSGLGPHR	CEP72	11	Q9P209
RAKSGLGPHRDLAEL	CEP72	16	Q9P209
LGGRKLHLEDSATTR	CELSR1	2716	Q9NYQ6
TRLKKCHIAVGSPGR	DDX20	176	Q9UHI6
KLVGTQHPLLTTARG	PDSS2	86	Q86YH6
QKRLSSSRLLHQPGG	DDN	511	O94850
HSPLSRAGTSVIKER	DACH2	356	Q96NX9
RAALTGLLHRTSVPK	HADHB	81	P55084
AAGSRTPELHLSGKL	ADAMTS14	21	Q8WXS8
RLVSGHISDSIPGLK	SLC16A2	371	P36021
RGGRELGTFHSRLIK	RBPJL	176	Q9UBG7
AKRGGQHTLPALSRA	RGS3	446	P49796
HRSDLVSGRLPVGLS	JAK3	141	P52333
RVSREGGVLKVHPTS	ISYNA1	31	Q9NPH2
QHGSLFLRTPKIVSG	LDHA	66	P00338
LRPKTGVRGLHKSLT	PDGFC	311	Q9NRA1
LTSRLPKTGETIHGH	RBKS	31	Q9H477
RGDSGGPLIVHKRSR	CFB	696	P00751
KTGRLLISHEAPLTG	BCKDHB	321	P21953
EAHDGPGLRARSKVL	PCDHGA4	351	Q9Y5G9
TGSKKHDVRSLIGSP	NCOR2	1466	Q9Y618
TKISPALGAERHSVG	MEGF11	836	A6BM72
KKGDTPLHIAIRGRS	KIDINS220	366	Q9ULH0
SGATVDSGKHRVLPV	MICAL3	1766	Q7RTP6
GTVKIPVIRHGTDLS	FRAS1	2811	Q86XX4
SRGHKLTVTLSCGRP	MAD2L1BP	236	Q15013
KIEGRLPVARSAHGA	LZTR1	166	Q8N653
DEGHVVLASPLKTGR	MEPCE	246	Q7L2J0
GSTEKGLPLRKTHVL	MFSD9	226	Q8NBP5
LPILSSKKTRRHTEG	COL11A1	1546	P12107
TKGHGRDVTASLLPV	FAM90A27P	196	A6NNH2
TVSITHPRRGSLELK	PCSK7	531	Q16549
GRTLHSFVRDPKTSL	KSR1	691	Q8IVT5
GRGSKRSPHAIVVTQ	PDZD2	351	O15018
TLSPGSVAHLDGRLR	IL16	386	Q14005
KHRDRAERTGPSGTV	DDX28	386	Q9NUL7
STARKGRGALPVAES	PI4KA	116	P42356
HASTGREGRKKPLTS	EXPH5	1131	Q8NEV8
PALVRLSLGSHRVKG	AP5B1	661	Q2VPB7
RKTRHDVGLPGVSRA	NOP14	46	P78316
VSSKNISLHGDGPLR	PELP1	351	Q8IZL8
HLRSKSDPGKTGLLS	ARHGAP32	1791	A7KAX9
PRTHEGGTKLLALSA	FAAP100	411	Q0VG06
FHVLRSLPLSSKGSG	ITGB5	86	P18084
IPGSILSHKTSRDRG	ODAD1	541	Q96M63
PGISAEGNVRSRHKL	KIAA1328	31	Q86T90
RPEHVSRLATGLSKS	NLRC5	1336	Q86WI3
ALGPAAEGARRLHKS	TENT4A	71	Q5XG87
HSNLGARPKGLSTLV	RABGAP1L	521	Q5R372
PRSARTGHLVTKVVA	PCDHAC1	571	Q9H158
VKKGSLADTVGHLRP	RIMS2	701	Q9UQ26
LLRRKRGHASSGAAP	POU2AF1	31	Q16633
SGTAAAHKVLPRGLS	PGR	176	P06401
KGSTSLLVHPVSGVR	FZD6	681	O60353
TKLLARPGTGEHREF	FBF1	251	Q8TES7
GIDKRGHLTAPDTTV	GRHL1	131	Q9NZI5
RFSKGLNGTPRELRH	KDM2B	996	Q8NHM5
TGALHLRRVESGGAK	CASC3	56	O15234
TRGEGPLKTSQDLIH	CTNNAL1	611	Q9UBT7
PDLLTVRKSGVSRTH	CACNA1G	2031	O43497
HVRGSGRSGKTIPEL	CEP290	2116	O15078
HGRTVIATRASDGKP	COL19A1	206	Q14993
HSIAGIIRSPKSALG	FER	426	P16591
ELRELSGHRKPGTTK	FCRLA	341	Q7L513
HESTPLRGRQKTGLD	FN1	1436	P02751
RSILSRLASKGTEPH	CHD3	1901	Q12873
DISPSTLRKHTRLAG	BCLAF1	656	Q9NYF8
IERGHPRILGSSCKT	C9orf43	31	Q8TAL5
LIGESTIRRTSEPHG	CR1L	516	Q2VPA4
LTKSPASAGDHVGRL	CCDC13	486	Q8IYE1
VEKHLGRPSESSARG	COBL	776	O75128
LRKTAEHTGEGRPAK	COBL	1126	O75128
TPGRIKDHLQSGRLD	DDX50	266	Q9BQ39
LKESGSPGHSARVVT	DHRSX	166	Q8N5I4
AKTRDGLTPLHCGAR	ANK3	296	Q12955
HRSSSLKGDSPLVKG	ANKMY1	426	Q9P2S6
TREPRKIILHKGSTG	DLG3	381	Q92796
LPKTSSGRRRVHDGK	BRWD1	1291	Q9NSI6
LEGLKPASHSGIRTS	B3GNT3	306	Q9Y2A9
DGKSRLVLLSERAHG	MAN2B2	766	Q9Y2E5
SPLDRLGTGGTHEVK	MAST3	621	O60307
SGSQARPHLSGRKLS	CAMKK2	86	Q96RR4
DSVTGTLPKVHRTGA	KLKB1	81	P03952
GPISSSVGRGHKIRS	KIAA1210	1506	Q9ULL0
TKERISPGIRGTHKL	HDAC9	426	Q9UKV0
VKFPEILATLRGHSG	HIRA	161	P54198
ALHGKFRSLLTTEPR	GTDC1	441	Q4AE62
RSLGLPIAASSEGHR	BICRA	1206	Q9NZM4
LSKGRAALSATVPRH	SCNN1D	331	P51172
LVSHSGTVKRPVLEG	PRRT3	211	Q5FWE3
GLQELKRRRGPASSH	nan	676	A6NNC1
REGGRTPTLEILKSH	FES	416	P07332
HRRLVLSGPSGTGKT	NAV1	1551	Q8NEY1
IVHLTLPDGTKRSGQ	ATP6V1B2	71	P21281
TSLPKERGSTRVHAL	UTRN	76	P46939
RRPSGTSHNALKILG	RIMBP2	776	O15034
SRLSPKHRDEGRKTG	SRRM3	276	A6NNA2
KRRSGLFPRLHTGSE	RAP1GAP2	561	Q684P5
LSRGTLESLRKVSHP	TMCO5B	281	A8MYB1
KGTGRARHGSIRSPL	MRPL4	131	Q9BYD3
LLPEGTGRFHSTAKT	SSPOP	2271	A2VEC9
PELGKLADSSRTLRH	SYNM	1436	O15061
LHRGRKKATGSPVSI	SCYL1	31	Q96KG9
GHASDTRPTKGLRQT	TEDC2	131	Q7L2K0
GLTRPHADTGSIRSL	PLD1	616	Q13393
SVLLPLGLRKAHSGA	YARS2	21	Q9Y2Z4
RVKGREASGKPSHLR	ODAD3	26	A5D8V7
KLHDSSLGLARTPAG	FEZF1	421	A0PJY2
KGRTKVSHPALLSDG	LAMA1	2781	P25391
GHTKGVSAVRLFPLS	CDC40	286	O60508
PALGIRKRHSSGSAS	SGSM2	221	O43147
RHTLGGPRSSKEILG	KIAA1217	66	Q5T5P2
TKELDPRGVHGSSLL	SHKBP1	81	Q8TBC3
SLDLLPSVHGARGRA	SHISA6	16	Q6ZSJ9
TRSVRAPVTKVHGGS	PDLIM3	271	Q53GG5
LTIPSRCGKGSLHRI	IARS1	506	P41252
RHLVLAGGSKPRDVT	SUPT5H	641	O00267
PLRAGEEGSHSRKSL	SIRT7	346	Q9NRC8
KPITQLLGRTHTATG	ITGAM	216	P11215
KGERSLRDSSHLPQL	OR8S1	296	Q8NH09
LGGLTSIVPHRKSDL	SLC28A2	546	O43868
LLGAAGHRSRRPSTE	SPTBN5	11	Q9NRC6
DIDVEHGGKRSRLTP	SQSTM1	256	Q13501
SLDGRLQVSHRKGLP	SMAD5	71	Q99717
LERHGGHKTPRRDSS	PRKAB1	11	Q9Y478
RLSDHPDVRKIGFTG	ALDH1L1	636	O75891
EHRGLGAGVSKVRSL	ARAP1	576	Q96P48
GKLPRLETDSGLEHS	C15orf39	16	Q6ZRI6
HETRPGSKAKGRSSI	LINC02694	21	Q8NAA6
RTRKVSLATIHPSGL	PPP1R27	51	Q86WC6
EIKELRSRSGPTAHL	TRAK2	346	O60296
VTGRQCPGLLSRHKT	ZNF540	71	Q8NDQ6
VGKEHSSTVLTGLRP	TNN	931	Q9UQP3
GTTGLPKAAIVVHSR	SLC27A1	251	Q6PCB7
ALGPGSRESTLRRHA	PLPPR3	676	Q6T4P5
GLGSTHLTRDGERKS	POLK	401	Q9UBT6
GLRSTDLPGLKAATH	TNC	1216	P24821
IKRLSPLEALSSGRH	WDFY4	2301	Q6ZS81
IVSAELTGRHKGPLA	TMPRSS9	131	Q7Z410
RSSVIPRHGLQSLGK	PRRC2B	36	Q5JSZ5
KRGTSLHSRRGKPEA	TMCC1	116	O94876
LHKGCGPSRRSDLQS	VRK3	361	Q8IV63
LLEKTTASHEGRAPG	NT5DC2	21	Q9H857
QTDKPHLVSLGSGRL	PHLDB1	36	Q86UU1
ARSESPRLSRKGGHE	PHLDB1	306	Q86UU1
HEGKRLGPLSAEGTT	TNXA	116	Q16473
HGVLRSRDPTGSKVL	TTPA	101	P49638
ATGPTETQIKRGLHL	SERPINA10	116	Q9UK55
SGLTRHKRIHSGEKP	ZNF264	496	O43296
LSSKPGHLGTATREL	VWA5B2	341	Q8N398
HGKASISPSSGARRT	ZNF101	146	Q8IZC7
EKGLSSTIRVVGHVP	TMEM130	86	Q8N3G9
LSLDPKDFSRGTHRG	TRAPPC9	441	Q96Q05
VLSKPGGSLASHVAR	PLEKHG2	1236	Q9H7P9
KEKELPSGSHIGDRR	ZSCAN29	201	Q8IWY8
ASSPDSGHLKDGIRR	ZNF367	131	Q7RTV3
TEGVKRRVKSPGSGH	TRIM2	431	Q9C040
DLKGRVSRGIPTHRS	WDR11	736	Q9BZH6
LGTRKPSDGTVSHLL	TBX19	6	O60806
SSTLKTGHIRPAVGL	UHRF1BP1	1246	Q6BDS2
RRIKPAATSHVEGSG	ZNF512	81	Q96ME7
TAPVRRIEHLGSTKS	TNS2	91	Q63HR2
SGLTRHQRIHSGEKP	ZNF805	496	Q5CZA5
SPAKRRLSTLILHGG	TERF2IP	36	Q9NYB0
LLSDIHLGPTVGRTK	TMPPE	211	Q6ZT21
VSIPASSHGKRGLSV	LIMK1	166	P53667
ISGTHLRVSDLQPGK	MYOM3	856	Q5VTT5
RKLRAVGTLEGSSPH	PDE4DIP	1396	Q5VU43
KGGAPLDTSRVHVRT	MYBPC2	876	Q14324
TPLHIAAGRGSTRLA	NFKB1	721	P19838