Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9 PZP	1.42e-04	105	150	6	GO:0004867
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1D CACNA1F CACNA1S	1.42e-04	14	150	3	GO:0008331
GeneOntologyMolecularFunction	DNA-dependent protein kinase activity	PRKDC ATM	1.67e-04	3	150	2	GO:0004677
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	PRKDC ATM	1.67e-04	3	150	2	GO:0035979
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	SERPINA3 SERPINA6 NLRP2 SERPINB5 SERPINB6 SERPINB9 PZP	4.29e-04	180	150	7	GO:0004866
GeneOntologyMolecularFunction	peptidase inhibitor activity	SERPINA3 SERPINA6 NLRP2 SERPINB5 SERPINB6 SERPINB9 PZP	5.39e-04	187	150	7	GO:0030414
GeneOntologyMolecularFunction	histone H2AX kinase activity	PRKDC ATM	5.52e-04	5	150	2	GO:0141003
GeneOntologyMolecularFunction	collagen receptor activity	DDR1 ITGA2	8.24e-04	6	150	2	GO:0038064
GeneOntologyMolecularFunction	endopeptidase regulator activity	SERPINA3 SERPINA6 NLRP2 SERPINB5 SERPINB6 SERPINB9 PZP	8.25e-04	201	150	7	GO:0061135
GeneOntologyBiologicalProcess	sensory organ development	EPHB2 CACNA1F CACNA1S DDR1 SP3 FLT1 RIPOR2 DLL4 POU2F1 CHD7 HOXA13 LRIG3 PPP2R3A NF1 NECTIN1 AHR DIAPH3 NOTCH2 LARGE1	1.87e-06	730	152	19	GO:0007423
GeneOntologyBiologicalProcess	visual system development	EPHB2 CACNA1F CACNA1S SP3 FLT1 DLL4 POU2F1 CHD7 ITGAM PPP2R3A NF1 NECTIN1 AHR NOTCH2 LARGE1	2.99e-06	483	152	15	GO:0150063
GeneOntologyBiologicalProcess	sensory system development	EPHB2 CACNA1F CACNA1S SP3 FLT1 DLL4 POU2F1 CHD7 ITGAM PPP2R3A NF1 NECTIN1 AHR NOTCH2 LARGE1	3.65e-06	491	152	15	GO:0048880
GeneOntologyBiologicalProcess	sensory organ morphogenesis	EPHB2 SP3 FLT1 RIPOR2 POU2F1 CHD7 LRIG3 PPP2R3A NF1 NECTIN1 NOTCH2 LARGE1	9.36e-06	343	152	12	GO:0090596
GeneOntologyBiologicalProcess	eye development	EPHB2 CACNA1F CACNA1S SP3 FLT1 DLL4 POU2F1 CHD7 PPP2R3A NF1 NECTIN1 AHR NOTCH2 LARGE1	1.32e-05	480	152	14	GO:0001654
GeneOntologyBiologicalProcess	camera-type eye development	EPHB2 CACNA1F CACNA1S SP3 FLT1 DLL4 POU2F1 CHD7 NF1 NECTIN1 AHR NOTCH2 LARGE1	1.69e-05	426	152	13	GO:0043010
GeneOntologyBiologicalProcess	eye morphogenesis	EPHB2 SP3 FLT1 POU2F1 PPP2R3A NF1 NECTIN1 NOTCH2 LARGE1	2.10e-05	204	152	9	GO:0048592
GeneOntologyBiologicalProcess	camera-type eye morphogenesis	EPHB2 SP3 FLT1 POU2F1 NF1 NECTIN1 NOTCH2 LARGE1	4.03e-05	171	152	8	GO:0048593
GeneOntologyBiologicalProcess	regulation of organelle assembly	EPHB2 ATMIN RIPOR2 SYNE1 TBC1D5 ATG2A CNOT6 ODF2L CNOT6L ATM	4.47e-05	280	152	10	GO:1902115
GeneOntologyBiologicalProcess	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	ATRX TNKS	5.40e-05	2	152	2	GO:1904908
GeneOntologyBiologicalProcess	regulation of maintenance of mitotic sister chromatid cohesion, telomeric	ATRX TNKS	5.40e-05	2	152	2	GO:1904907
GeneOntologyBiologicalProcess	mitotic sister chromatid cohesion, telomeric	ATRX TNKS	5.40e-05	2	152	2	GO:0099404
GeneOntologyBiologicalProcess	maintenance of mitotic sister chromatid cohesion, telomeric	ATRX TNKS	5.40e-05	2	152	2	GO:0099403
GeneOntologyBiologicalProcess	artery morphogenesis	MYLK DLL4 CHD7 TFAP2B HOXA13 NF1	6.14e-05	92	152	6	GO:0048844
GeneOntologyBiologicalProcess	protein localization to chromosome, telomeric region	ATRX XRCC5 TNKS PML	8.68e-05	32	152	4	GO:0070198
GeneOntologyBiologicalProcess	signal transduction by p53 class mediator	ATRX DYRK1A PPP1R13B PRMT5 PAXIP1 TAF1 ATM PML	8.79e-05	191	152	8	GO:0072331
GeneOntologyBiologicalProcess	cytosolic small ribosomal subunit assembly	XRCC5 PRKDC	1.61e-04	3	152	2	GO:0180025
GeneOntologyBiologicalProcess	small-subunit processome assembly	XRCC5 PRKDC	1.61e-04	3	152	2	GO:0034462
GeneOntologyBiologicalProcess	negative regulation of maintenance of sister chromatid cohesion	ATRX TNKS	1.61e-04	3	152	2	GO:0034092
GeneOntologyBiologicalProcess	negative regulation of maintenance of mitotic sister chromatid cohesion	ATRX TNKS	1.61e-04	3	152	2	GO:0034183
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	EPHB2 ATMIN DDR1 RIPOR2 ATRX SYNE1 TBC1D5 DUSP3 ADGRB3 ITGA2 ATG2A XRCC5 CNOT6 HOXA13 NF1 CNOT6L AHR TMEM30A TNKS TACR1 ATM ROBO3 PML	1.69e-04	1366	152	23	GO:0051130
GeneOntologyBiologicalProcess	positive regulation of telomere maintenance	ATRX XRCC5 TNKS ATM PML	1.91e-04	72	152	5	GO:0032206
GeneOntologyBiologicalProcess	autophagy of peroxisome	ATG2A PEX5 ATM	2.05e-04	16	152	3	GO:0030242
GeneOntologyBiologicalProcess	aorta morphogenesis	MYLK DLL4 CHD7 TFAP2B	2.32e-04	41	152	4	GO:0035909
GeneOntologyBiologicalProcess	DNA damage response, signal transduction by p53 class mediator	ATRX DYRK1A PAXIP1 ATM PML	2.79e-04	78	152	5	GO:0030330
GeneOntologyBiologicalProcess	regulation of organelle organization	EPHB2 ATMIN RIPOR2 ATRX CENPF SYNE1 TBC1D5 DYRK1A ATG2A XRCC5 CNOT6 HOXA13 LMOD3 ODF2L CNOT6L WDHD1 PRMT5 TNKS TACR1 ATM DIAPH3 PML	3.43e-04	1342	152	22	GO:0033043
Domain	VDCC_L_a1su	CACNA1D CACNA1F CACNA1S	1.98e-06	4	149	3	IPR005446
Domain	Serpin_CS	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	5.11e-06	32	149	5	IPR023795
Domain	Serpin_dom	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	9.33e-06	36	149	5	IPR023796
Domain	SERPIN	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	1.07e-05	37	149	5	PS00284
Domain	SERPIN	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	1.07e-05	37	149	5	SM00093
Domain	Serpin	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	1.23e-05	38	149	5	PF00079
Domain	Serpin_fam	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	1.40e-05	39	149	5	IPR000215
Domain	Ca_chan_IQ	CACNA1D CACNA1F CACNA1S	1.70e-05	7	149	3	SM01062
Domain	Ca_chan_IQ	CACNA1D CACNA1F CACNA1S	1.70e-05	7	149	3	PF08763
Domain	VDCC_a1su_IQ	CACNA1D CACNA1F CACNA1S	1.70e-05	7	149	3	IPR014873
Domain	GPHH	CACNA1D CACNA1F CACNA1S	1.70e-05	7	149	3	PF16905
Domain	GPHH_dom	CACNA1D CACNA1F CACNA1S	1.70e-05	7	149	3	IPR031649
Domain	VDCCAlpha1	CACNA1D CACNA1F CACNA1S	5.73e-05	10	149	3	IPR002077
Domain	CAC1F_C	CACNA1D CACNA1F	1.89e-04	3	149	2	IPR031688
Domain	UPF0560	FAM171A1 FAM171A2	1.89e-04	3	149	2	PF10577
Domain	CAC1F_C	CACNA1D CACNA1F	1.89e-04	3	149	2	PF16885
Domain	Uncharacterised_FAM171	FAM171A1 FAM171A2	1.89e-04	3	149	2	IPR018890
Domain	Integrin_alpha_C_CS	ITGA2 ITGA4 ITGAM	2.58e-04	16	149	3	IPR018184
Domain	Integrin_alpha-2	ITGA2 ITGA4 ITGAM	3.72e-04	18	149	3	IPR013649
Domain	INTEGRIN_ALPHA	ITGA2 ITGA4 ITGAM	3.72e-04	18	149	3	PS00242
Domain	Integrin_alpha2	ITGA2 ITGA4 ITGAM	3.72e-04	18	149	3	PF08441
Domain	Integrin_alpha	ITGA2 ITGA4 ITGAM	3.72e-04	18	149	3	IPR000413
Domain	Serpin_B9/Maspin	SERPINB5 SERPINB9	3.75e-04	4	149	2	IPR000240
Domain	Int_alpha	ITGA2 ITGA4 ITGAM	4.39e-04	19	149	3	SM00191
Domain	Int_alpha_beta-p	ITGA2 ITGA4 ITGAM	4.39e-04	19	149	3	IPR013519
Domain	FATC	PRKDC ATM	6.22e-04	5	149	2	PF02260
Domain	FG_GAP	ITGA2 ITGA4 ITGAM	6.86e-04	22	149	3	PS51470
Domain	FG-GAP	ITGA2 ITGA4 ITGAM	8.91e-04	24	149	3	PF01839
Domain	FG-GAP	ITGA2 ITGA4 ITGAM	8.91e-04	24	149	3	IPR013517
Domain	FAT	PRKDC ATM	9.29e-04	6	149	2	PS51189
Domain	FATC	PRKDC ATM	9.29e-04	6	149	2	PS51190
Domain	FAT	PRKDC ATM	9.29e-04	6	149	2	PF02259
Domain	PIK-rel_kinase_FAT	PRKDC ATM	9.29e-04	6	149	2	IPR003151
Domain	FATC_dom	PRKDC ATM	9.29e-04	6	149	2	IPR003152
Domain	PIK_FAT	PRKDC ATM	9.29e-04	6	149	2	IPR014009
Domain	FATC	PRKDC ATM	9.29e-04	6	149	2	SM01343
Domain	Integrin_dom	ITGA2 ITGA4 ITGAM	1.01e-03	25	149	3	IPR032695
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1D CACNA1F CACNA1S	9.60e-06	6	112	3	M47762
Pathway	REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ	XRCC5 PAXIP1 PRKDC ATM HERC2	3.40e-05	47	112	5	MM15296
Pathway	KEGG_MEDICUS_REFERENCE_NON_HOMOLOGOUS_END_JOINING	XRCC5 PAXIP1 PRKDC	1.32e-04	13	112	3	M47837
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	CACNA1D CACNA1F CACNA1S	1.67e-04	14	112	3	M47692
Pathway	REACTOME_NONHOMOLOGOUS_END_JOINING_NHEJ	XRCC5 PAXIP1 PRKDC ATM HERC2	2.03e-04	68	112	5	M27587
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYLC1 MYLK ATRX KRT18 ACADVL CENPF PYROXD1 SYNE1 HMOX2 XRCC5 LRRC43 ABCB1 LMOD3 LRPPRC RNF2 N4BP2 DGKK UGP2 FUNDC2 MYH15 PRKDC ATM DIAPH3 PRRC2B	1.85e-08	1442	152	24	35575683
Pubmed	[Potentials of DNA-PKcs, Ku80, and ATM in enhancing radiosensitivity of cervical carcinoma cells].	XRCC5 PRKDC ATM	8.18e-08	3	152	3	17626748
Pubmed	Structure and chromosomal location of the gene encoding mouse corticosteroid-binding globulin: strain differences in coding sequence and steroid-binding activity.	SERPINA3 SERPINA6 AHR	8.18e-08	3	152	3	8039711
Pubmed	ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks.	XRCC5 PRKDC ATM	8.18e-08	3	152	3	32890395
Pubmed	Wortmannin potentiates integrase-mediated killing of lymphocytes and reduces the efficiency of stable transduction by retroviruses.	XRCC5 PRKDC ATM	3.26e-07	4	152	3	11158303
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1D CACNA1F CACNA1S	3.26e-07	4	152	3	20937870
Pubmed	Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining.	XRCC5 PRKDC ATM	3.26e-07	4	152	3	28109743
Pubmed	Kinetochore protein MAD1 participates in the DNA damage response through ataxia-telangiectasia mutated kinase-mediated phosphorylation and enhanced interaction with KU80.	XRCC5 PRKDC ATM	3.26e-07	4	152	3	32944396
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 CACNA1S SP3 TBC1D5 CHD7 ATG2A TULP4 PEX5 TNKS ATM MGA MRTFA	4.69e-07	430	152	12	35044719
Pubmed	BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery.	XRCC5 PRKDC ATM	8.13e-07	5	152	3	20668194
Pubmed	Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.	XRCC5 PRKDC ATM	8.13e-07	5	152	3	11248063
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	KIAA0232 TBC1D5 DYRK1A PPP1R13B ATG2A ECPAS MAST2 ODF2L PPP2R3A N4BP2 PRMT5 PEX5 HERC2 MGA PRRC2B BRWD1	1.15e-06	853	152	16	28718761
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	COPB1 CENPF PUF60 CHD7 ECPAS XRCC5 LRPPRC NF1 PRMT5 PRKDC ATM HERC2 MTREX PRRC2B	1.19e-06	653	152	14	22586326
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CENPF SYNE1 TBC1D5 ADGRB3 DYRK1A CHD7 XRCC5 FAM171A1 LRPPRC NF1 FAM171A2 N4BP2 PEX5 TNKS HERC2 MGA PRRC2B	1.19e-06	963	152	17	28671696
Pubmed	Update of the human and mouse SERPIN gene superfamily.	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	1.26e-06	43	152	5	24172014
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KRT18 KIAA0232 TBC1D5 DYRK1A MAST2 FAM171A1 LRPPRC NF1 FAM171A2 N4BP2 PRMT5 NCOA7 MTREX NOTCH2 NOS1AP PML	1.30e-06	861	152	16	36931259
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	EPHB2 ATMIN SP3 ATRX DLL4 SPTLC1 SLC35A1 DYRK1A POU2F1 SIL1 PGM3 SERPINB6 NF1 PAXIP1 UGP2 AHR TMEM30A DIAPH3 MGA SLC23A1	1.49e-06	1327	152	20	32694731
Pubmed	DNA-PK suppresses a p53-independent apoptotic response to DNA damage.	XRCC5 PRKDC ATM	1.62e-06	6	152	3	19057578
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CENPF SYNE1 CHD7 XRCC5 RNF2 PRMT5 TNKS MTREX	2.68e-06	197	152	8	20811636
Pubmed	Centrosomal localization of DNA damage checkpoint proteins.	XRCC5 PRKDC ATM	2.83e-06	7	152	3	17171639
Pubmed	Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.	XRCC5 PRKDC ATM	2.83e-06	7	152	3	25818648
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1D CACNA1F CACNA1S	2.83e-06	7	152	3	12900400
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZNF821 ATRX COPB1 SYNE1 ADGRB3 DYRK1A NCAM2 HMOX2 ODF2L TNKS PRKDC TAF1 ATM HERC2 EXOC7 BACE2 ALDH5A1 SNX1 BRWD1	3.67e-06	1285	152	19	35914814
Pubmed	Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.	CACNA1D CACNA1F CACNA1S	4.51e-06	8	152	3	28330839
Pubmed	The binding of Ku antigen to homeodomain proteins promotes their phosphorylation by DNA-dependent protein kinase.	POU2F1 XRCC5 PRKDC	4.51e-06	8	152	3	11279128
Pubmed	Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.	XRCC5 NLRP2 PRKDC	4.51e-06	8	152	3	28345663
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	EPHB2 KRT18 COPB1 DPY19L1 TBC1D5 SPTLC1 DYRK1A ITGA2 HMOX2 XRCC5 ATL1 STX12 TMEM30A TNKS PRKDC MGA NOTCH2 PML	5.74e-06	1203	152	18	29180619
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	ATRX KRT18 PCNX3 CENPF	6.62e-06	28	152	4	20309963
Pubmed	Pellino1 specifically binds to phospho-Thr18 of p53 and is recruited to sites of DNA damage.	XRCC5 PRKDC HERC2	6.74e-06	9	152	3	30987826
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ATMIN PCNX3 PUF60 DYRK1A ATG2A SLC35E2B LARS2 MAST2 SIL1 TULP4 DEF6 PAXIP1 PRKDC HERC2 HERC1 NOTCH2 PRRC2B	7.41e-06	1105	152	17	35748872
Pubmed	The ATM cofactor ATMIN protects against oxidative stress and accumulation of DNA damage in the aging brain.	ATMIN ITGAM ATM	9.60e-06	10	152	3	20889973
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	DYRK1A CHD7 LRPPRC BRD9 PAXIP1 TNKS PRKDC TAF1 MGA SNX1	1.09e-05	398	152	10	35016035
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	KRT18 COPB1 ACADVL CENPF PUF60 SYNE1 XRCC5 ABCB1 LRPPRC NF1 PRMT5 PEX5 PRKDC HERC2 MTREX MGA	1.16e-05	1024	152	16	24711643
Pubmed	Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.	XRCC5 PRKDC ATM	1.32e-05	11	152	3	16400328
Pubmed	Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.	XRCC5 PRKDC ATM	1.32e-05	11	152	3	15758953
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	ITGA4 XRCC5 NLRP2 ABCB1 PRKDC ATM PML	1.47e-05	179	152	7	19074885
Pubmed	MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.	XRCC5 PRKDC ATM	1.75e-05	12	152	3	30017584
Pubmed	Trisomy 21 Alters DNA Methylation in Parent-of-Origin-Dependent and -Independent Manners.	DYRK1A BACE2 BRWD1	1.75e-05	12	152	3	27100087
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	SPTLC1 PPP1R13B ITGA2 ITGA4 FAM171A1 LRPPRC FAM171A2 SNX1 NOTCH2 NOS1AP	1.77e-05	421	152	10	36976175
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	EPHB2 DDR1 KIAA0232 SLC35A1 HMOX2 STX12 LRIG3 TRAFD1 NF1 AHR PRKDC ATM HERC1 ALDH5A1 SNX1 NOTCH2	1.78e-05	1061	152	16	33845483
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	KRT18 COPB1 SPTLC1 HMOX2 ECPAS XRCC5 PGM3 STX12 LRPPRC TRAFD1 MTX2 CNOT6L PRMT5 PRKDC ATM MTREX EXOC7 PRRC2B PML	1.82e-05	1440	152	19	30833792
Pubmed	A fraction of neurofibromin interacts with PML bodies in the nucleus of the CCF astrocytoma cell line.	NF1 PML	1.90e-05	2	152	2	22293200
Pubmed	Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.	PRKDC ATM	1.90e-05	2	152	2	10464290
Pubmed	Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.	PRKDC ATM	1.90e-05	2	152	2	27939942
Pubmed	The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.	PRKDC ATM	1.90e-05	2	152	2	21487018
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	1.90e-05	2	152	2	34788619
Pubmed	NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.	SERPINA3 SERPINA6	1.90e-05	2	152	2	31103428
Pubmed	ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.	ATMIN ATM	1.90e-05	2	152	2	21575860
Pubmed	Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.	CACNA1D CACNA1F	1.90e-05	2	152	2	25966695
Pubmed	Increased MDR1 Transporter Expression in Human Brain Endothelial Cells Through Enhanced Histone Acetylation and Activation of Aryl Hydrocarbon Receptor Signaling.	ABCB1 AHR	1.90e-05	2	152	2	30963442
Pubmed	ATMIN defines an NBS1-independent pathway of ATM signalling.	ATMIN ATM	1.90e-05	2	152	2	17525732
Pubmed	The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.	XRCC5 PRKDC	1.90e-05	2	152	2	11340158
Pubmed	Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma.	ATRX ATM	1.90e-05	2	152	2	29378238
Pubmed	Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.	PRKDC ATM	1.90e-05	2	152	2	12065055
Pubmed	Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.	CACNA1D CACNA1S	1.90e-05	2	152	2	28978442
Pubmed	Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway.	CYBB ITGAM	1.90e-05	2	152	2	28978491
Pubmed	Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.	PRKDC ATM	1.90e-05	2	152	2	17189255
Pubmed	AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.	PRKDC ATM	1.90e-05	2	152	2	22972376
Pubmed	Identification of rare missense mutations in NOTCH2 and HERC2 associated with familial central precocious puberty via whole-exome sequencing.	HERC2 NOTCH2	1.90e-05	2	152	2	32400230
Pubmed	Regulation of the Bcas1 and Baiap3 transcripts in the subthalamic nucleus in mice recovering from MPTP toxicity.	ADGRB3 BCAS1	1.90e-05	2	152	2	21514331
Pubmed	ABCB1 regulation through LRPPRC is influenced by the methylation status of the GC -100 box in its promoter.	ABCB1 LRPPRC	1.90e-05	2	152	2	25089713
Pubmed	Activities of DNA-PK and Ku86, but not Ku70, may predict sensitivity to cisplatin in human gliomas.	XRCC5 PRKDC	1.90e-05	2	152	2	18415044
Pubmed	MRTF-A regulates Ca2+ release through CACNA1S.	CACNA1S MRTFA	1.90e-05	2	152	2	33969828
Pubmed	NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.	NF1 ATM	1.90e-05	2	152	2	31664505
Pubmed	DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.	PRKDC ATM	1.90e-05	2	152	2	36727301
Pubmed	LRPPRC contributes to the cisplatin resistance of lung cancer cells by regulating MDR1 expression.	ABCB1 LRPPRC	1.90e-05	2	152	2	33649818
Pubmed	Blood-based DNA methylation of DNA repair genes in the non-homologous end-joining (NEHJ) pathway in patient with glioma.	XRCC5 PRKDC	1.90e-05	2	152	2	26464705
Pubmed	Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.	ITGA2 ITGA4	1.90e-05	2	152	2	26779610
Pubmed	[The expression of genes encoding the voltage-dependent L-type Ca2+ channels in proliferating and differentiating C2C12 myoblasts of mice].	CACNA1D CACNA1S	1.90e-05	2	152	2	21789999
Pubmed	Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.	PRKDC ATM	1.90e-05	2	152	2	20617180
Pubmed	Complement receptor 3 deficiency influences lesion progression during Leishmania major infection in BALB/c mice.	ITGAM PRKDC	1.90e-05	2	152	2	19797068
Pubmed	Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine.	XRCC5 ATM	1.90e-05	2	152	2	16916625
Pubmed	Correlation between genetic polymorphisms of the hOCT1 and MDR1 genes and the response to imatinib in patients newly diagnosed with chronic-phase chronic myeloid leukemia.	POU2F1 ABCB1	1.90e-05	2	152	2	21185600
Pubmed	DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair.	XRCC5 PRKDC	1.90e-05	2	152	2	28154079
Pubmed	Downregulation of DNA-PKcs suppresses P-gp expression via inhibition of the Akt/NF-κB pathway in CD133-positive osteosarcoma MG-63 cells.	ABCB1 PRKDC	1.90e-05	2	152	2	27499034
Pubmed	Blockade of class IA phosphoinositide 3-kinase in neutrophils prevents NADPH oxidase activation- and adhesion-dependent inflammation.	CYBB ITGAM	1.90e-05	2	152	2	17197441
Pubmed	DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.	PRKDC ATM	1.90e-05	2	152	2	18172300
Pubmed	Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.	PRKDC ATM	1.90e-05	2	152	2	11231155
Pubmed	Down-regulation of histone H2B by DNA-dependent protein kinase in response to DNA damage through modulation of octamer transcription factor 1.	POU2F1 PRKDC	1.90e-05	2	152	2	14612514
Pubmed	Novel mechanism of negative regulation of 1,25-dihydroxyvitamin D3-induced 25-hydroxyvitamin D3 24-hydroxylase (Cyp24a1) Transcription: epigenetic modification involving cross-talk between protein-arginine methyltransferase 5 and the SWI/SNF complex.	CYP24A1 PRMT5	1.90e-05	2	152	2	25324546
Pubmed	Activation of DNA Damage Response Pathways during Lytic Replication of KSHV.	PRKDC ATM	1.90e-05	2	152	2	26057167
Pubmed	Low ABCB1 and high OCT1 levels play a favorable role in the molecular response to imatinib in CML patients in the community clinical practice.	POU2F1 ABCB1	1.90e-05	2	152	2	27770655
Pubmed	Transfer of type II collagen-induced arthritis from DBA/1 to severe combined immunodeficiency mice can be prevented by blockade of Mac-1.	ITGAM PRKDC	1.90e-05	2	152	2	8690467
Pubmed	Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.	FLT1 PRKDC	1.90e-05	2	152	2	28377452
Pubmed	DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.	PRKDC ATM	1.90e-05	2	152	2	19071136
Pubmed	G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.	PRKDC ATM	1.90e-05	2	152	2	26774662
Pubmed	Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats.	XRCC5 PRKDC	1.90e-05	2	152	2	20023628
Pubmed	Patients with low OCT-1 activity and high ABCB1 fold rise have poor long-term outcomes in response to tyrosine kinase inhibitor therapy.	POU2F1 ABCB1	1.90e-05	2	152	2	29654270
Pubmed	C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.	CACNA1D CACNA1F	1.90e-05	2	152	2	16921373
Pubmed	Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.	TNKS PRKDC	1.90e-05	2	152	2	21037379
Pubmed	Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock.	SERPINA3 SERPINA6	1.90e-05	2	152	2	10049582
Pubmed	Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.	PRKDC ATM	1.90e-05	2	152	2	32674014
Pubmed	Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.	PRKDC ATM	1.90e-05	2	152	2	21245310
Pubmed	The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.	PRKDC ATM	1.90e-05	2	152	2	17593081
Pubmed	[Effects of hOCT1 and ABCB1 gene on the efficacy of imatinib mesylate in chronic myelocytic leukemia].	POU2F1 ABCB1	1.90e-05	2	152	2	22883199
Pubmed	DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining.	XRCC5 PRKDC	1.90e-05	2	152	2	18653525
Pubmed	The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.	CNOT6 CNOT6L	1.90e-05	2	152	2	21233283
Pubmed	MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity.	CYBB ITGAM	1.90e-05	2	152	2	17654704
Pubmed	Absence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic models.	ITGA2 ITGA4	1.90e-05	2	152	2	19463772
Pubmed	PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.	MYLK ITGA4	1.90e-05	2	152	2	35365657
Cytoband	15q22	HERC1 PML MPI	1.22e-04	29	152	3	15q22
Cytoband	9q21.2	PRUNE2 CEP78	4.82e-04	10	152	2	9q21.2
Cytoband	14q32.1	SERPINA3 SERPINA6	5.87e-04	11	152	2	14q32.1
GeneFamily	Serpin peptidase inhibitors	SERPINA3 SERPINA6 SERPINB5 SERPINB6 SERPINB9	1.17e-06	37	92	5	739
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA2 ITGA4 ITGAM	9.84e-05	18	92	3	1160
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	FLT1 MYLK NCAM2 IGSF10 LRIG3 ROBO3	1.72e-04	161	92	6	593
GeneFamily	Calcium voltage-gated channel subunits	CACNA1D CACNA1F CACNA1S	3.05e-04	26	92	3	253
GeneFamily	X-linked mental retardation\|RNA helicases	ATRX MTREX	1.37e-03	11	92	2	1168
GeneFamily	CCR4-NOT transcription complex	CNOT6 CNOT6L	1.37e-03	11	92	2	1023
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	DDR1 ITGA2 ITGA4 ITGAM ABCB1 NECTIN1 CD300E	3.96e-03	394	92	7	471
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	CHD7 MAST2 NF1 CNOT6L TULP4 TNKS ATM HERC1	1.02e-05	180	151	8	M8239
Coexpression	GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP	CACNA1D KIAA0232 ITGAM LRPPRC PRKDC TAF1 MTREX PRRC2B	1.96e-05	197	151	8	M8022
Coexpression	GSE3982_MAC_VS_BCELL_DN	KRT18 SYNE1 TBC1D5 DYRK1A SLC35E2B DEF6 PRKDC BACE2	1.96e-05	197	151	8	M5495
Coexpression	NAKAYA_B_CELL_FLUMIST_AGE_18_50YO_7DY_UP	ATMIN DDR1 RIPOR2 TBC1D5 SPTLC1 PPP1R13B ABCB1 NF1 TNKS ATM MRTFA LARGE1	2.11e-05	475	151	12	M40979
Coexpression	GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN	MYLK PUF60 ITGA4 XRCC5 DDC SERPINB6 PRMT5 DIAPH3	2.18e-05	200	151	8	M317
Coexpression	GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN	DDR1 COPB1 PDHA2 HMOX2 XRCC5 ABCB1 CNOT6L MRTFA	2.18e-05	200	151	8	M5128
Coexpression	GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP	BTBD6 PYROXD1 DUSP3 ITGAM SERPINB6 NF1 KLHL13 BRWD1	2.18e-05	200	151	8	M6600
Coexpression	GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP	PYROXD1 PUF60 SPTLC1 XRCC5 DDC ABCB1 TACR1 PRRC2B	2.18e-05	200	151	8	M5231
Coexpression	CUI_TCF21_TARGETS_2_DN	CYBB FLT1 RIPOR2 DUSP3 PPP1R13B ITGA2 ITGA4 MYZAP ECPAS ABCB1 COLEC12 SERPINB6 UGP2 MMRN2 TMEM150C TMEM30A	3.57e-05	854	151	16	M1533
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EPHB2 SP3 ATRX CENPF DYRK1A LARS2 MAST2 FAM171A1 LRPPRC PPP2R3A MTX2 RNF2 WDHD1 TNKS MTREX MRTFA	3.67e-05	856	151	16	M4500
Coexpression	CUI_TCF21_TARGETS_2_DN	CYBB FLT1 RIPOR2 DUSP3 PPP1R13B ITGA2 ITGA4 MYZAP ECPAS ABCB1 COLEC12 SERPINB6 UGP2 MMRN2 TMEM150C TMEM30A	5.66e-05	888	151	16	MM1018
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	ACADVL TBC1D5 ITGA2 PPP2R3A NCOA7 NOS1AP BRWD1	5.79e-05	169	151	7	M39230
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	RIPOR2 ATRX POU2F1 SHISAL1 ATL1 LMOD3 PPP2R3A CNOT6L TULP4 N4BP2 KLHL13 NECTIN1 NCOA7 TNKS HERC1 SNX1 PRRC2B BRWD1	7.09e-05	1106	151	18	M39071
Coexpression	BOSCO_INTERFERON_INDUCED_ANTIVIRAL_MODULE	CYP24A1 ITGA4 TRAFD1 NCOA7 PML	8.94e-05	78	151	5	M2532
Coexpression	BRUINS_UVC_RESPONSE_LATE	FLT1 SPTLC1 DYRK1A PPP1R13B HMOX2 SIL1 STX12 ABCB1 LRIG3 COLEC12 ODF2L SERPINB9 MTX2 KLHL13 NECTIN1 AHR ROBO3 SNX1	9.95e-05	1136	151	18	M2247
Coexpression	GSE23321_CENTRAL_MEMORY_VS_NAIVE_CD8_TCELL_DN	CYBB ZNF821 TFAP2B NECTIN1 MYH15 MGA BRWD1	1.51e-04	197	151	7	M8431
Coexpression	GSE3982_EOSINOPHIL_VS_BCELL_DN	PCBP3 TBC1D5 SLC35E2B LARS2 SERPINB9 PRMT5 PRRC2B	1.56e-04	198	151	7	M5411
Coexpression	GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP	KRT18 PCDHB14 DDC ABCB1 AHR NCOA7 TMEM30A	1.61e-04	199	151	7	M7553
Coexpression	GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN	CYBB DDR1 ECPAS XRCC5 ITGAM UGP2 TACR1	1.66e-04	200	151	7	M9606
Coexpression	GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP	CYBB CHD7 SERPINB9 TRAFD1 CNOT6L NCOA7 PML	1.66e-04	200	151	7	M8559
Coexpression	GSE33424_CD161_INT_VS_NEG_CD8_TCELL_UP	CYBB CHD7 ABCB1 TRAFD1 PRMT5 NCOA7 PML	1.66e-04	200	151	7	M8554
Coexpression	GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_DN	FLT1 PYROXD1 SPTLC1 SLC35A1 NPEPL1 PRMT5 PRKDC	1.66e-04	200	151	7	M3880
Coexpression	GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP	DDR1 SP3 ABCB1 MTX2 CNOT6L RNF2 EML5	1.66e-04	200	151	7	M5119
Coexpression	GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP	ZNF821 PCNX3 DPY19L1 ACADVL ODF2L NF1 NCOA7	1.66e-04	200	151	7	M6524
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4	ATRX COPB1 DYRK1A POU2F1 CHD7 ECPAS ODF2L TAF1 BRWD1	1.04e-05	203	144	9	Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
ToppCell	mild-gd_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ATG2A ABCB1 ODF2L CNOT6L CEP78 NCOA7 ATM PZP	3.07e-08	200	152	9	109f673a4967ffa52270a0b4f818b3461288db44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 TCN2 SYNE1 DUSP3 ITGA2 MYZAP FAM171A2 AHR	1.24e-07	169	152	8	41ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 TCN2 SYNE1 DUSP3 ITGA2 MYZAP FAM171A2 AHR	1.24e-07	169	152	8	42782c61592742190ab0cba8a94f8bdf9c278f90
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT1 DLL4 POU2F1 ITGA2 EML5 MMRN2 TMEM150C PML	1.49e-07	173	152	8	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PCBP3 DLL4 DUSP3 PCDHB14 ITGA2 MYZAP AHR MMRN2	2.10e-07	181	152	8	9cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCell	normal-na-Lymphocytic_T-CytoT_GZMK+-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ATRX SYNE1 ATG2A ITGA4 CNOT6L CEP78 NCOA7 ATM	2.29e-07	183	152	8	79defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	RIPOR2 ITGA4 ABCB1 CNOT6L CEP78 DGKK ATM PZP	2.48e-07	185	152	8	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	Control-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLT1 DLL4 ABCB1 FAM171A1 SERPINB9 TMEM150C BACE2 PML	2.92e-07	189	152	8	5d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCN2 DLL4 PPP1R13B MYZAP LARS2 MMRN2 TMEM30A MTREX	3.71e-07	195	152	8	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 ATM PZP	4.16e-07	198	152	8	a1b310274aa9b3d2aa1fe9488d67422bf4ac81d2
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 CACNA1D DDR1 KRT18 FAM171A1 LRIG3 SERPINB5 SERPINB6	4.16e-07	198	152	8	a4543d636501a1b5b46c14a661ce9d169947c82c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 ATM PZP	4.16e-07	198	152	8	a781fd35a7cda8b7760c2e3ddccaac7aac26c979
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 CACNA1D DDR1 KRT18 ITGA2 FAM171A1 LRIG3 SERPINB5	4.16e-07	198	152	8	e8bfae3888b2406b5629b576cb02913b3297337e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 ATM PZP	4.16e-07	198	152	8	df399674345c45738d765a8354ea8d1484572c34
ToppCell	COVID-19_Mild-Lymphoid_T/NK-gd_T\|COVID-19_Mild / Disease group, lineage and cell class	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 ATM PZP	4.16e-07	198	152	8	6aea5d00c417708f05b6d2dfe5a962d80864f8eb
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-gd_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 ATM PZP	4.16e-07	198	152	8	76aff381403bc5a8a9cc73eb1e5dbdc0bac7de6c
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-gd_T\|COVID-19_Mild / Disease, condition lineage and cell class	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 ATM PZP	4.49e-07	200	152	8	6560753d3df2f87860b52052d4881aa45410f666
ToppCell	mild-CD8+_Tem\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ATRX SYNE1 ATG2A ITGA4 CNOT6L CEP78 ATM PZP	4.49e-07	200	152	8	d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 SYNE1 ITGA4 ITGAM CNOT6L CEP78 PZP	2.50e-06	176	152	7	6b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCBP3 BCAS1 ABCB1 FAM171A1 AHR NCOA7 BACE2	2.79e-06	179	152	7	d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 RIPOR2 SYNE1 CYP24A1 PPP1R13B PPP2R3A DIAPH3	3.60e-06	186	152	7	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	EC-Sinusoidal_ECs\|World / Lineage and Cell class	FLT1 TCN2 DLL4 MYZAP FAM171A1 MMRN2 BACE2	4.00e-06	189	152	7	9a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ITGA2 FAM171A1 CNOT6L KLHL13 BACE2 NOS1AP	4.00e-06	189	152	7	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	RIPOR2 SYNE1 ITGA4 ABCB1 CNOT6L CEP78 PZP	4.00e-06	189	152	7	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	RIPOR2 MYLK HMOX2 BRD9 UGP2 ATM	4.13e-06	123	152	6	511b7c20a4a85e49980936d52af7dbca19bb848e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 ITGA2 TFAP2B PPP2R3A KLHL13 DIAPH3 NOS1AP	4.14e-06	190	152	7	bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ITGA2 TFAP2B FAM171A1 KLHL13 BACE2 NOS1AP	4.14e-06	190	152	7	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 ITGA2 TFAP2B PPP2R3A KLHL13 DIAPH3 NOS1AP	4.14e-06	190	152	7	b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 DLL4 DUSP3 MYZAP FAM171A1 MMRN2 BACE2	4.28e-06	191	152	7	1924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 DLL4 DUSP3 MYZAP FAM171A1 MMRN2 BACE2	4.28e-06	191	152	7	88f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	KRT18 CYP24A1 ITGA2 LRIG3 SERPINB5 NECTIN1 BACE2	4.43e-06	192	152	7	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ATRX POU2F1 CNOT6 LRPPRC N4BP2 PRKDC MGA	4.59e-06	193	152	7	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 TCN2 DLL4 DUSP3 MYZAP AHR MMRN2	4.59e-06	193	152	7	b7c0b4dbbe11f86cff6371d3d12a6b772b938d78
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLT1 TCN2 DLL4 DUSP3 MYZAP AHR MMRN2	4.59e-06	193	152	7	e44d777f65b907f299cefd73296805ac4c92d383
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 DLL4 DUSP3 MYZAP FAM171A1 MMRN2 BACE2	4.91e-06	195	152	7	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1D ATRX DDC TULP4 HERC1 BACE2 MGA	4.91e-06	195	152	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	facs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 TCN2 DLL4 FAM171A1 MMRN2 NCOA7 MTREX	4.91e-06	195	152	7	3969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell	systemic_lupus_erythematosus-treated\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RIPOR2 ATRX SYNE1 ITGA4 CEP78 UGP2 ATM	5.42e-06	198	152	7	8165ff735095c52994fb5057d89be93cc378b7da
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RIPOR2 ATRX SYNE1 ITGA4 CEP78 UGP2 ATM	5.42e-06	198	152	7	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	SERPINA3 FLT1 ABCB1 PPP2R3A NCOA7 TACR1 BACE2	5.42e-06	198	152	7	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	MS-IIF-Others-HSPC\|IIF / Disease, condition lineage and cell class	CACNA1F KRT18 TIGD4 ITGA4 SIL1 ATL1 IGSF10	5.61e-06	199	152	7	3384db80f6024bcabe2625f24d5f4e0d3d8caa7e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DDR1 KRT18 CYP24A1 ITGA2 SERPINB5 NECTIN1 NCOA7	5.61e-06	199	152	7	c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCell	mild-gd_T\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 ATG2A ABCB1 ODF2L CNOT6L NCOA7 PZP	5.79e-06	200	152	7	2c21ede46a42b8e2f8e99ecca365baa52056eb17
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	FLT1 DLL4 ITGA2 FAM171A1 AHR TMEM150C PML	5.79e-06	200	152	7	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	DLL4 ITGA4 MYZAP FAM171A1 SERPINB6 AHR BACE2	5.79e-06	200	152	7	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLT1 ATRX DLL4 CHD7 FAM171A1 AHR BRWD1	5.79e-06	200	152	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 CACNA1D KRT18 SI DDC SERPINB5 SERPINB6	5.79e-06	200	152	7	742441800a2d167c19cee4816ff77424ae6675c6
ToppCell	5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPHB2 CACNA1D KRT18 SI DDC SERPINB5 SERPINB6	5.79e-06	200	152	7	fc77a0c53201c60933d188ea8d4d86bac6325422
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLT1 DLL4 MYZAP FAM171A1 SERPINB6 AHR BACE2	5.79e-06	200	152	7	89a6da2bdedc6b1ad0675c8753bf2b763a99af6a
ToppCell	Club_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	IGSF10 NECTIN1 TMEM150C MTREX BACE2 NOS1AP	1.15e-05	147	152	6	9211242a8e40d50414d310940616eccce299a7f8
ToppCell	droplet-Fat-SCAT-30m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB RBM44 AASDH ITGA2 ITGA4 TMEM150C	1.44e-05	153	152	6	2731c3d4ac40ecc22108f8f3f45a069077159125
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	FLT1 MYZAP ATL1 AHR MMRN2 BACE2	1.50e-05	154	152	6	928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RIPOR2 SYNE1 ITGAM CEP78 DEF6 ATM	1.80e-05	159	152	6	bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1D MYLK FAM171A1 COLEC12 LMOD3 MMRN2	2.62e-05	170	152	6	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB CCDC192 ITGA4 ITGAM NECTIN1 CD300E	2.71e-05	171	152	6	00739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 MYZAP FAM171A1 AHR MMRN2 BACE2	2.71e-05	171	152	6	3112d15f2a28cf4a71992db4971d960716dc1264
ToppCell	CD8+_Memory_T_cell-FLU-3\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	ATP8B3 DPY19L1 SPTLC1 ECPAS MAST2 DIAPH3	2.80e-05	172	152	6	45ac433dbb3796f69e886c04457b2971403050ee
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CYBB CCDC192 ITGA4 ITGAM NECTIN1 CD300E	2.80e-05	172	152	6	5f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CACNA1D FLT1 MYLK FAM171A1 COLEC12 AHR	3.08e-05	175	152	6	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell	droplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB CCDC192 ITGA4 NECTIN1 CD300E NOTCH2	3.08e-05	175	152	6	c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYBB CCDC192 ITGA4 NECTIN1 CD300E NOTCH2	3.08e-05	175	152	6	61fbd8f685d3daad46449e4c0386a38886496566
ToppCell	droplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S CHD7 NIBAN3 EML5 TMEM150C NCOA7	3.18e-05	176	152	6	24b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCell	droplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 DLL4 PCDHB14 ATL1 FAM171A1 MMRN2	3.18e-05	176	152	6	3494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 RIPOR2 SYNE1 BCAS1 DIAPH3 LARGE1	3.18e-05	176	152	6	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	droplet-Liver-Npc-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 DLL4 PCDHB14 ATL1 FAM171A1 MMRN2	3.18e-05	176	152	6	d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCell	COPD-Epithelial-Aberrant_Basaloid\|COPD / Disease state, Lineage and Cell class	EPHB2 SERPINA3 DDR1 PCDHB14 ITGA2 LRIG3	3.18e-05	176	152	6	11d867bcb4f2471b4e13a5f7dc1c24286197f26d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CACNA1S CHD7 NIBAN3 EML5 TMEM150C NCOA7	3.28e-05	177	152	6	f360f7099570d248531897b96e0de282e58f59e9
ToppCell	COVID-19_Convalescent-Classical_Monocyte-cMono_4\|COVID-19_Convalescent / Disease condition and Cell class	POU2F1 ATG2A SLC35E2B SERPINB9 NF1 RFPL2	3.50e-05	179	152	6	366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DDR1 KRT18 CYP24A1 ITGA2 TMEM150C NCOA7	3.61e-05	180	152	6	255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RIPOR2 ITGA4 CNOT6L CEP78 ATM PZP	3.72e-05	181	152	6	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF821 FLT1 PCDHB14 ATL1 FAM171A1 BACE2	3.72e-05	181	152	6	4df7972f88117108698efd06b124b232f8588981
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF821 FLT1 PCDHB14 ATL1 FAM171A1 BACE2	3.72e-05	181	152	6	cbb530566893281289026bfd93adf721decd4ca3
ToppCell	(7)_Epithelial-H_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	DDR1 KRT18 CYP24A1 ITGA2 SERPINB5 NECTIN1	4.08e-05	184	152	6	1f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCell	P28-Endothelial\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 TCN2 DLL4 DUSP3 MYZAP MMRN2	4.08e-05	184	152	6	b056411f499866097f4322999cfd1e57a3927b78
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT1 DLL4 PCDHB14 FAM171A1 MMRN2 BACE2	4.20e-05	185	152	6	742350093d90f96735dc73e3360cdd749bae63fd
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	RIPOR2 ITGA4 ABCB1 CNOT6L ATM PZP	4.20e-05	185	152	6	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AASDH ITGAM NPEPL1 PGM3 CEP78 MGA	4.20e-05	185	152	6	7925519b855f76444a0b57382ce35d89457b0b14
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RIPOR2 SYNE1 ITGA4 CNOT6L CEP78 ATM	4.33e-05	186	152	6	71e87c4c755ab607689cb050f5a363cb520a0f53
ToppCell	E17.5-Endothelial-capillary_endothelial_cell-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 TCN2 DLL4 MYZAP AHR MMRN2	4.46e-05	187	152	6	e9aa0a5a0f8e2593de63e83b56b53ae33e60af49
ToppCell	E17.5-Endothelial-capillary_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 TCN2 DLL4 MYZAP AHR MMRN2	4.46e-05	187	152	6	61b8a53f29bb8b33c69f680b8359a1143a23999d
ToppCell	COVID-19-kidney-DCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1D TFAP2B PPP2R3A KLHL13 BACE2 NOS1AP	4.60e-05	188	152	6	1d56cd409793f05cca20757ab26e91f1a1ee67b5
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RIPOR2 ITGA4 ABCB1 CNOT6L CEP78 ATM	4.60e-05	188	152	6	1082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SYNE1 BCAS1 KLHL13 DIAPH3 LARGE1	4.60e-05	188	152	6	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 CACNA1D DDC EML5 BACE2 PRRC2B	4.60e-05	188	152	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	P03-Endothelial\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 TCN2 DUSP3 MYZAP AHR MMRN2	4.60e-05	188	152	6	88d477aad98be124919b9c6b0b8dbd24e556422e
ToppCell	Healthy_donor-NK_CD56bright\|World / disease group, cell group and cell class (v2)	SYNE1 ATG2A NLRP2 ABCB1 CEP78 ATM	4.60e-05	188	152	6	8ee359199c61c3b5b498ac35148390db5cc1a836
ToppCell	15-Airway-Epithelial-Basal_cell\|Airway / Age, Tissue, Lineage and Cell class	DDR1 KRT18 CYP24A1 ITGA2 TMEM150C NCOA7	4.73e-05	189	152	6	f128c2fc37f232d193de18a922c47fdd70e1982d
ToppCell	Monocytes-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	CYBB RIPOR2 SLC35A1 ITGAM SERPINB9 CD300E	4.73e-05	189	152	6	22d08c7dde697f385100f72e009eeac8d19d329d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 RIPOR2 KRT18 CYP24A1 FAM171A2 DIAPH3	4.73e-05	189	152	6	bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLT1 TCN2 DLL4 PPP1R13B ITGA2 MMRN2	4.73e-05	189	152	6	9e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell	P07-Endothelial\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FLT1 TCN2 DUSP3 MYZAP AHR MMRN2	4.73e-05	189	152	6	d62b5b5c3cd259befa7afb19f45e3804e2ab80f7
ToppCell	IPF-Lymphoid-NK\|IPF / Disease state, Lineage and Cell class	SYNE1 ITGA4 ABCB1 CNOT6L CEP78 ATM	4.73e-05	189	152	6	d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCell	3'_v3-blood-Lymphocytic_T_CD8\|blood / Manually curated celltypes from each tissue	RIPOR2 ATRX SYNE1 ITGA4 ATM PZP	4.87e-05	190	152	6	5dca8654964c41580fa3b094579fe7cb296d406f
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	KRT18 CYP24A1 ITGA2 LRIG3 SERPINB5 NECTIN1	4.87e-05	190	152	6	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RIPOR2 ITGA4 ABCB1 CNOT6L ATM PZP	4.87e-05	190	152	6	2a8de1cf27a9ebc3825cf9e7a489ecd064dfc7f9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 SYNE1 BCAS1 TFAP2B KLHL13 DIAPH3	4.87e-05	190	152	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	COVID-19-kidney-NK\|kidney / Disease (COVID-19 only), tissue and cell type	RIPOR2 ITGA4 CNOT6L CEP78 ATM PZP	4.87e-05	190	152	6	e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1D ITGA2 FAM171A1 KLHL13 BACE2 NOS1AP	4.87e-05	190	152	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	facs-Lung-3m-Endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLT1 TCN2 DLL4 DUSP3 MYZAP MMRN2	4.87e-05	190	152	6	d55b3ad4d1ec172b042bc08127506c354f87f69d
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	FLT1 TCN2 DUSP3 MYZAP AHR MMRN2	4.87e-05	190	152	6	1357bd4527399d7013ee33272bda7453f472999a
Drug	dihydrosanguinarine	SYNE1 ITGA2 AHR	1.12e-06	4	150	3	CID000124069
Drug	CHAPSO	CACNA1S TCN2 SERPINA6 BACE2 NOTCH2	4.89e-06	38	150	5	CID000122145
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; PC3; HT_HG-U133A	TBC1D5 ECPAS MAST2 SHISAL1 NF1 RNF2 ROBO3 PML BRWD1	5.80e-06	194	150	9	3807_DN
Drug	Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; MCF7; HT_HG-U133A	CYLC1 ZNF821 SPTLC1 ITGA2 PPP2R3A WDHD1 EXOC7 SNX1 PRRC2B	6.31e-06	196	150	9	4815_DN
Drug	Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	EPHB2 CENPF PDHA2 ATG2A MMRN2 ATM ROBO3 NOS1AP MPI	6.57e-06	197	150	9	2821_UP
Drug	Trichlorfon [52-68-6]; Down 200; 15.6uM; HL60; HT_HG-U133A	TBC1D5 DUSP3 ITGA2 HMOX2 TRAFD1 NF1 BRD9 EXOC7 NOTCH2	6.84e-06	198	150	9	1839_DN
Drug	quinazoline	FLT1 SYNE1 ITGA2 ABCB1 PRKDC MPI	7.44e-06	71	150	6	CID000009210
Drug	6-fluoranyl-7H-purine	SP3 ITGA2 SIL1	9.62e-06	7	150	3	CID005462117
Drug	pyranocoumarin	FLT1 ITGAM DDC SERPINB6	9.93e-06	21	150	4	CID000010606
Drug	Cinnarizine	CACNA1D CACNA1F CACNA1S	2.29e-05	9	150	3	DB00568
Drug	Nimodipine	CACNA1D CACNA1F CACNA1S	2.29e-05	9	150	3	DB00393
Drug	B led	POU2F1 XRCC5 NLRP2 PRKDC	2.42e-05	26	150	4	CID000068703
Drug	fluoranthene	FLT1 SPTLC1 SIL1 AHR MPI	2.58e-05	53	150	5	CID000009154
Drug	methyl methanesulfonate	ATMIN POU2F1 XRCC5 NLRP2 ABCB1 CNOT6 CNOT6L NECTIN1 TNKS PRKDC ATM	3.08e-05	364	150	11	CID000004156
Drug	TEMPOL-H	ITGAM PRKDC ATM	3.25e-05	10	150	3	ctd:C505333
Drug	7-amino-AMD	KRT18 ITGA2 ITGA4 ITGAM ABCB1	4.02e-05	58	150	5	CID000065180
Drug	dihydrorhodamine 123	CYBB SPTLC1 HMOX2 ITGAM ATL1	4.02e-05	58	150	5	CID000105032
Drug	14-hydroxy-10-deacetylbaccatin III	DYRK1A ABCB1	4.31e-05	2	150	2	CID005318183
Drug	6-bromopurine	ITGA2 SIL1	4.31e-05	2	150	2	CID005287830
Drug	topsentin	SYNE1 ITGA2	4.31e-05	2	150	2	CID000072457
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; HL60; HT_HG-U133A	DUSP3 DYRK1A NPEPL1 SIL1 PGM3 PEX5 TAF1 EXOC7	4.34e-05	193	150	8	2996_DN
Drug	Diprophylline [479-18-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	MYLK ITGA2 SHISAL1 PPP2R3A WDHD1 DEF6 EXOC7 SNX1	4.34e-05	193	150	8	1811_DN
Drug	Mibefradil	CACNA1D CACNA1F CACNA1S	4.45e-05	11	150	3	DB01388
Drug	dithiane	SP3 SYNE1 ABCB1	4.45e-05	11	150	3	CID000136335
Drug	carbanilide	ITGA4 SIL1 AHR	4.45e-05	11	150	3	CID000007595
Drug	4-amino-1,8-naphthalimide	XRCC5 PRKDC ATM	4.45e-05	11	150	3	ctd:C086538
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	EPHB2 ZNF821 MYLK DEF6 ATM ROBO3 NOS1AP PML	4.51e-05	194	150	8	4763_DN
Drug	phentolamine; Up 200; 11.5uM; MCF7; HT_HG-U133A_EA	HMOX2 MAST2 NPEPL1 SIL1 TRAFD1 AHR TNKS ATM	4.51e-05	194	150	8	1138_UP
Drug	Dobutamine hydrochloride [49745-95-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	EPHB2 CENPF MAST2 COLEC12 NF1 DEF6 MRTFA PML	4.67e-05	195	150	8	5386_UP
Drug	Estradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A	PDHA2 SERPINA6 WDHD1 MGA NOTCH2 MRTFA NOS1AP PML	4.67e-05	195	150	8	2653_UP
Drug	Leflunomide [75706-12-6]; Up 200; 14.8uM; PC3; HT_HG-U133A	TBC1D5 CYP24A1 HMOX2 NF1 TACR1 EXOC7 MRTFA PML	4.67e-05	195	150	8	5884_UP
Drug	Asiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A	EPHB2 SERPINA3 MAST2 PGM3 NF1 TAF1 SNX1 NOTCH2	4.67e-05	195	150	8	3504_DN
Drug	Prilocaine hydrochloride [1786-81-8]; Down 200; 15.6uM; MCF7; HT_HG-U133A	PPP2R3A SERPINB9 NF1 RNF2 WDHD1 ROBO3 MRTFA PML	4.85e-05	196	150	8	4749_DN
Drug	6-Hydroxytropinone [5932-53-6]; Up 200; 25.8uM; MCF7; HT_HG-U133A	EPHB2 ZNF821 MYLK TBC1D5 NF1 RNF2 ATM MRTFA	4.85e-05	196	150	8	7346_UP
Drug	Acetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A	EPHB2 TBC1D5 MAST2 RNF2 NECTIN1 ATM NOS1AP PML	5.02e-05	197	150	8	3364_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A	EPHB2 CACNA1D SYNE1 DEF6 MMRN2 ROBO3 MRTFA NOS1AP	5.02e-05	197	150	8	4767_DN
Drug	Lansoprazole [103577-45-3]; Up 200; 10.8uM; MCF7; HT_HG-U133A	CACNA1D ZNF821 TFAP2B TRAFD1 NECTIN1 PRRC2B MRTFA PML	5.02e-05	197	150	8	6009_UP
Drug	Enoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A	EPHB2 PRUNE2 ZNF821 RIPOR2 ECPAS COLEC12 NOS1AP PML	5.02e-05	197	150	8	5616_UP
Drug	Adenosine 5'-monophosphate monohydrate [18422-05-4]; Up 200; 11uM; MCF7; HT_HG-U133A	EPHB2 CYBB CACNA1D DYRK1A PPP2R3A TRAFD1 EXOC7 PML	5.21e-05	198	150	8	3237_UP
Drug	Nizatidine [76963-41-2]; Up 200; 12uM; MCF7; HT_HG-U133A	PRUNE2 TSNAXIP1 MYLK CENPF ADGRB3 NECTIN1 MRTFA PML	5.21e-05	198	150	8	5406_UP
Drug	PF-00562151-00 [351320-12-2]; Up 200; 10uM; PC3; HT_HG-U133A	SPTLC1 ITGA2 NF1 WDHD1 EXOC7 NOTCH2 PML BRWD1	5.21e-05	198	150	8	6907_UP
Drug	Fendiline hydrochloride [13636-18-5]; Down 200; 11.4uM; MCF7; HT_HG-U133A	CYBB TBC1D5 ECPAS NF1 EXOC7 NOTCH2 MRTFA PML	5.21e-05	198	150	8	3190_DN
Drug	isobutanol	CACNA1D ITGA2 SIL1 PEX5 MPI	5.55e-05	62	150	5	CID000006560
Drug	Clomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A	EPHB2 RIPOR2 PDHA2 MAST2 NF1 MYH15 ROBO3 PML	5.59e-05	200	150	8	3182_UP
Drug	Pyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A	EPHB2 PCBP3 SYNE1 ECPAS MAST2 ALDH5A1 MRTFA PML	5.59e-05	200	150	8	1474_UP
Drug	AC1LAPJB	SP3 ITGA2 ATM	5.90e-05	12	150	3	CID000517869
Drug	napabucasin	DDR1 ITGA2 ITGA4 ATM NOTCH2	6.47e-05	64	150	5	ctd:C000621033
Drug	9,10-dimethylanthracene	SIL1 CNOT6 AHR	7.64e-05	13	150	3	CID000013076
Drug	MCNU	TCN2 ITGAM ABCB1 MPI	9.05e-05	36	150	4	CID000071741
Drug	N-methylpyridinium	POU2F1 SIL1 AHR	9.67e-05	14	150	3	CID000013597
Drug	AD 288	ABCB1 PRKDC ATM	9.67e-05	14	150	3	CID000073553
Drug	4-hydroxycyclophosphamide	SYNE1 AASDH XRCC5 PRKDC	1.12e-04	38	150	4	CID000099735
Drug	Val-Val	ITGA4 ABCB1 SERPINB6 BACE2	1.24e-04	39	150	4	CID000107475
Drug	m-benzenediacetic acid	SYNE1 ITGA2	1.29e-04	3	150	2	CID000029788
Drug	nilvadipine	FLT1 ABCB1	1.29e-04	3	150	2	ctd:C035100
Drug	benzo(b)chrysene	SIL1 AHR	1.29e-04	3	150	2	CID000009163
Drug	riccardin D	ATRX XRCC5 N4BP2 PRKDC ATM	1.47e-04	76	150	5	ctd:C547185
Drug	Verapamil	CACNA1D CACNA1F CACNA1S	1.47e-04	16	150	3	DB00661
Drug	CH2S	SYNE1 HMOX2 AHR	1.47e-04	16	150	3	CID000079115
Drug	desmethoxyverapamil	CACNA1S ABCB1 TACR1	1.78e-04	17	150	3	CID000065832
Drug	dehydrophenylalanine	HMOX2 ITGA4 TACR1	1.78e-04	17	150	3	CID005702627
Drug	Sesquimustard	ITGA2 ITGA4 ITGAM MPI	1.83e-04	43	150	4	CID000019092
Drug	Pt-F	SP3 POU2F1 SERPINB6 NF1 BACE2	1.99e-04	81	150	5	CID000013016
Drug	N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester	FLT1 ITGAM NOTCH2 PML	2.00e-04	44	150	4	ctd:C419410
Drug	Isradipine	CACNA1D CACNA1F AHR	2.13e-04	18	150	3	ctd:D017275
Drug	Adamantamine fumarate [80789-67-9]; Down 200; 9.6uM; HL60; HT_HG-U133A	TBC1D5 SPTLC1 ITGA2 ITGA4 ECPAS TAF1 BRWD1	2.24e-04	184	150	7	1344_DN
Drug	Diethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A	PCBP3 CENPF CYP24A1 SERPINB9 NECTIN1 NOS1AP PML	2.24e-04	184	150	7	4369_UP
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; HL60; HT_HG-U133A	CHD7 ITGA4 LRPPRC TNKS PRKDC ALDH5A1 SNX1	2.31e-04	185	150	7	2927_DN
Drug	tetraphenylphosphonium	MYLK ITGA2 ABCB1	2.51e-04	19	150	3	CID000164911
Drug	Apa-sg	XRCC5 ABCB1 PRKDC	2.51e-04	19	150	3	CID000126348
Drug	DMAB	TCN2 HMOX2 ABCB1 CNOT6 CNOT6L PML	2.55e-04	133	150	6	CID000006053
Drug	P-CTAS	ITGA2 AHR	2.56e-04	4	150	2	CID000015766
Drug	N-nitro-N-nitrosoguanidine	DDC PEX5	2.56e-04	4	150	2	CID003015677
Drug	IC86621	XRCC5 PRKDC	2.56e-04	4	150	2	CID009859309
Drug	cinnamyl chloride	SYNE1 ITGA2	2.56e-04	4	150	2	CID000094242
Drug	Xanthenes	ABCB1 AHR	2.56e-04	4	150	2	ctd:D014966
Drug	MS-073	ABCB1 TACR1	2.56e-04	4	150	2	CID000131119
Drug	sulfinosine	SYNE1 ABCB1	2.56e-04	4	150	2	CID000130209
Drug	AC1L2NMW	ITGA2 SERPINA6	2.56e-04	4	150	2	CID000024733
Drug	2-[1-(benzyloxycarbonylamino)hexyl-hydroxy-phosphoryl]oxy-2-(3-guanidinophenyl)acetic acid	SYNE1 ITGA2 ITGAM PEX5 MPI	2.63e-04	86	150	5	CID010174526
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; PC3; HT_HG-U133A	EPHB2 CYLC1 ATRX CENPF MAST2 NF1 PEX5	2.63e-04	189	150	7	5084_DN
Drug	cobalt-60	CACNA1D CACNA1F CACNA1S FLT1 TCN2 ITGA2 HMOX2 NPEPL1 DDC NECTIN1	2.71e-04	390	150	10	CID000061492
Drug	Sulconazole nitrate [61318-91-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A	ZNF821 HMOX2 RNF2 NECTIN1 ATM NOTCH2 MRTFA	2.72e-04	190	150	7	3373_DN
Drug	Tiabendazole [148-79-8]; Up 200; 19.8uM; MCF7; HT_HG-U133A	EPHB2 SERPINB9 NF1 TAF1 ATM MRTFA NOS1AP	2.81e-04	191	150	7	2840_UP
Drug	Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A	TSNAXIP1 CACNA1D RIPOR2 ADGRB3 SERPINB5 TRAFD1 NF1	2.81e-04	191	150	7	3574_UP
Drug	Beta-Escin [11072-93-8]; Down 200; 3.2uM; MCF7; HT_HG-U133A	ATRX MAST2 PPP2R3A NF1 PEX5 MRTFA PML	2.81e-04	191	150	7	3890_DN
Drug	KU55933	XRCC5 NLRP2 PRKDC ATM	2.81e-04	48	150	4	CID005278396
Drug	di-fluoro	SYNE1 ITGA2 TAF1 BACE2	2.81e-04	48	150	4	CID000069610
Drug	Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	TBC1D5 MAST2 SERPINB9 NF1 PEX5 ATM NOTCH2	2.90e-04	192	150	7	3318_DN
Drug	Phenacetin [62-44-2]; Down 200; 22.4uM; HL60; HT_HG-U133A	ATRX DUSP3 MAST2 NF1 AHR EXOC7 MRTFA	2.90e-04	192	150	7	2471_DN
Drug	metolachlor	EPHB2 SP3 DUSP3 DYRK1A ABCB1	2.93e-04	88	150	5	CID000004169
Drug	o-108	SERPINA3 KRT18 SIL1	2.94e-04	20	150	3	CID000007120
Drug	cyclopentadiene	SP3 SYNE1 ITGA2	2.94e-04	20	150	3	CID000007612
Drug	Glycocholic acid [475-31-0]; Down 200; 8.6uM; PC3; HT_HG-U133A	TBC1D5 SPTLC1 DEF6 PRKDC TAF1 ATM NOTCH2	2.99e-04	193	150	7	6716_DN
Drug	Levodopa [59-92-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A	EPHB2 PPP2R3A NF1 PEX5 EXOC7 MRTFA PML	2.99e-04	193	150	7	4394_DN
Drug	Dilazep dihydrochloride [20153-98-4]; Down 200; 6uM; PC3; HT_HG-U133A	CYLC1 SYNE1 TBC1D5 MAST2 DEF6 PML MPI	2.99e-04	193	150	7	7364_DN
Drug	n-butan-2-yl-l-homocysteine	HMOX2 XRCC5 AHR PRKDC	3.05e-04	49	150	4	CID000160683
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	PRUNE2 TSNAXIP1 ZNF821 BCAS1 ATG2A TRAFD1 ALDH5A1	3.09e-04	194	150	7	7001_UP
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A	EPHB2 MAST2 ATM EXOC7 ALDH5A1 NOTCH2 PML	3.09e-04	194	150	7	4524_DN
Drug	Moroxidine hydrochloride [3160-91-6]; Down 200; 19.2uM; PC3; HT_HG-U133A	SYNE1 TBC1D5 PEX5 PRKDC TAF1 NOTCH2 MRTFA	3.09e-04	194	150	7	6705_DN
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1D CACNA1F CACNA1S	4.93e-07	4	148	3	DOID:0060173 (implicated_via_orthology)
Disease	Malignant neoplasm of prostate	EPHB2 SERPINA3 DDR1 TCN2 CENPF CHD7 BCAS1 SIL1 AHR NCOA7 PRKDC ATM MGA PML	2.92e-06	616	148	14	C0376358
Disease	Prostatic Neoplasms	SERPINA3 DDR1 TCN2 CENPF CHD7 BCAS1 SIL1 AHR NCOA7 PRKDC ATM MGA PML	1.47e-05	616	148	13	C0033578
Disease	Breast Carcinoma	FLT1 KRT18 CENPF DLL4 SYNE1 CYP24A1 ABCB1 SERPINB5 AHR ATM HERC2 NOTCH2	1.85e-05	538	148	12	C0678222
Disease	Malignant neoplasm of breast	FLT1 KRT18 CENPF DLL4 SYNE1 CYP24A1 SPTLC1 POU2F1 STX12 ABCB1 SERPINB5 NF1 N4BP2 AHR ATM HERC2 NOTCH2	2.93e-05	1074	148	17	C0006142
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1D CACNA1F CACNA1S NOS1AP	3.16e-05	36	148	4	DOID:11723 (implicated_via_orthology)
Disease	cancer (implicated_via_orthology)	FLT1 DLL4 PGM3 STX12 RNF2 UGP2 ATM NOTCH2	6.57e-05	268	148	8	DOID:162 (implicated_via_orthology)
Disease	Mammary Carcinoma, Human	FLT1 KRT18 CENPF DLL4 SYNE1 CYP24A1 ABCB1 SERPINB5 AHR ATM NOTCH2	7.28e-05	525	148	11	C4704874
Disease	Mammary Neoplasms, Human	FLT1 KRT18 CENPF DLL4 SYNE1 CYP24A1 ABCB1 SERPINB5 AHR ATM NOTCH2	7.28e-05	525	148	11	C1257931
Disease	Mammary Neoplasms	FLT1 KRT18 CENPF DLL4 SYNE1 CYP24A1 ABCB1 SERPINB5 AHR ATM NOTCH2	7.53e-05	527	148	11	C1458155
Disease	Intellectual Disability	TCN2 PUF60 SYNE1 ATL1 PGM3 NF1 UGP2 TAF1 ALDH5A1 LARGE1	9.14e-05	447	148	10	C3714756
Disease	nevus count, cutaneous melanoma	TFAP2B AHR ATM HERC2 NOTCH2	9.75e-05	91	148	5	EFO_0000389, EFO_0004632
Disease	JT interval	CACNA1D SP3 KIAA0232 LRIG3 NCOA7 NOS1AP BRWD1	2.66e-04	248	148	7	EFO_0007885
Disease	cognitive function measurement	CACNA1D PCBP3 DLL4 TBC1D5 NCAM2 CHD7 TFAP2B LRIG3 LRPPRC SERPINB6 TULP4 PAXIP1 MYH15 TNKS DIAPH3 BACE2 MRTFA LARGE1	3.16e-04	1434	148	18	EFO_0008354
Disease	lung small cell carcinoma (is_implicated_in)	ATRX CYP24A1 ATM	3.69e-04	28	148	3	DOID:5409 (is_implicated_in)
Disease	Vomiting	ABCB1 TACR1	5.16e-04	7	148	2	C0042963
Disease	immature granulocyte measurement	CHD7 ITGA4	5.16e-04	7	148	2	EFO_0803543
Disease	venous thromboembolism	TBC1D5 NCAM2 BCAS1 NLRP2 CNOT6 SERPINB6 SERPINB9 FUNDC2 BRWD1	5.46e-04	460	148	9	EFO_0004286
Disease	oxalate measurement	MYLK SIL1 SLC23A1	5.51e-04	32	148	3	EFO_0010517
Disease	Congenital disorder of glycosylation type 1q	SLC35A1 MPI	6.86e-04	8	148	2	C4317224
Disease	Leydig cell tumor (is_marker_for)	FLT1 PRMT5	6.86e-04	8	148	2	DOID:2696 (is_marker_for)
Disease	Hereditary Sensory Autonomic Neuropathy, Type 1	SPTLC1 ATL1	6.86e-04	8	148	2	C0020071
Disease	vitamin D measurement, vitamin D dietary intake measurement	CYP24A1 BCAS1	6.86e-04	8	148	2	EFO_0004631, EFO_0008539
Disease	age at initiation of corrective lens use	TBC1D5 BRWD1	6.86e-04	8	148	2	EFO_0021781
Disease	Adenoma, Microcystic	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0205648
Disease	Adenoma, Monomorphic	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0205649
Disease	Adenoma, Basal Cell	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0205646
Disease	Follicular adenoma	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0205647
Disease	Papillary adenoma	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0205650
Disease	Adenoma, Trabecular	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0205651
Disease	Adenoma	CACNA1D TCN2 NF1	7.82e-04	36	148	3	C0001430
Disease	human immunodeficiency virus infectious disease (is_marker_for)	EPHB2 ABCB1 ATM	7.82e-04	36	148	3	DOID:526 (is_marker_for)
Disease	Neoplasm Metastasis	FLT1 MYLK ABCB1 SERPINB5 AHR PML	8.17e-04	217	148	6	C0027627
Disease	rectum cancer (is_implicated_in)	CYP24A1 XRCC5	8.79e-04	9	148	2	DOID:1993 (is_implicated_in)
Disease	alpha-1-antitrypsin measurement	SERPINA3 SERPINA6	8.79e-04	9	148	2	EFO_0008327
Disease	Glioma	MYLK ATRX NF1 ATM	9.79e-04	87	148	4	C0017638
Disease	Cleft upper lip	TCN2 TFAP2B NECTIN1	9.90e-04	39	148	3	C0008924
Disease	Congenital Disorders of Glycosylation	SLC35A1 MPI	1.10e-03	10	148	2	C0282577
Disease	age at onset, alcohol dependence	SI NCAM2 LARGE1	1.23e-03	42	148	3	EFO_0004847, MONDO_0007079
Disease	sleep disorder (implicated_via_orthology)	TFAP2B NF1	1.33e-03	11	148	2	DOID:535 (implicated_via_orthology)
Disease	refractive error	CACNA1D FLT1 PCBP3 CHD7 TFAP2B LRPPRC ATM	1.33e-03	326	148	7	MONDO_0004892
Disease	creatinine measurement	CACNA1S KRT18 CENPF CYP24A1 BCAS1 MAST2 HOXA13 MTX2 RNF2 AHR NCOA7 SLC23A1 MRTFA	1.56e-03	995	148	13	EFO_0004518
Disease	retinopathy of prematurity (biomarker_via_orthology)	FLT1 DLL4	1.60e-03	12	148	2	DOID:13025 (biomarker_via_orthology)
Disease	Behavior Disorders	DDC ABCB1	1.60e-03	12	148	2	C0004930
Disease	Mental disorders	DDC ABCB1	1.60e-03	12	148	2	C0004936
Disease	Mental Disorders, Severe	DDC ABCB1	1.60e-03	12	148	2	C4046029
Disease	Diagnosis, Psychiatric	DDC ABCB1	1.60e-03	12	148	2	C0376338
Disease	Adenoid Cystic Carcinoma	ATRX PRKDC ATM MGA	1.64e-03	100	148	4	C0010606
Disease	end stage renal disease (biomarker_via_orthology)	CYBB DDC ABCB1	1.71e-03	47	148	3	DOID:783 (biomarker_via_orthology)
Disease	Liver Cirrhosis	FLT1 KRT18 SERPINA6 AHR	1.83e-03	103	148	4	C0023890
Disease	Respiratory Depression	CACNA1S SLC23A1	1.88e-03	13	148	2	C0235063
Disease	Respiratory Insufficiency	CACNA1S SLC23A1	1.88e-03	13	148	2	C0035229
Disease	Respiratory Failure	CACNA1S SLC23A1	1.88e-03	13	148	2	C1145670
Disease	vitamin D measurement, COVID-19	COPB1 CYP24A1 BCAS1	1.92e-03	49	148	3	EFO_0004631, MONDO_0100096
Disease	Fibrosis, Liver	FLT1 KRT18 SERPINA6 AHR	1.96e-03	105	148	4	C0239946
Disease	retinal drusen	ITGA2 COLEC12 SLC23A1	2.16e-03	51	148	3	EFO_1001155
Disease	Glioblastoma Multiforme	ATRX NF1 NOTCH2 PML	2.40e-03	111	148	4	C1621958
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	CACNA1D TBC1D5 NCAM2 CHD7 TFAP2B LRPPRC TULP4 PRKDC HERC1 PRRC2B BRWD1	2.44e-03	801	148	11	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	Neoplasm of uncertain or unknown behavior of bladder	ATM NOTCH2	2.51e-03	15	148	2	C0496930
Disease	Benign neoplasm of bladder	ATM NOTCH2	2.51e-03	15	148	2	C0154017
Disease	Carcinoma in situ of bladder	ATM NOTCH2	2.51e-03	15	148	2	C0154091
Disease	Necrosis	KRT18 PUF60 AHR	2.68e-03	55	148	3	C0027540
Disease	autism spectrum disorder (is_implicated_in)	DYRK1A ITGA4	2.86e-03	16	148	2	DOID:0060041 (is_implicated_in)
Disease	Pheochromocytoma, Extra-Adrenal	DDC NF1	2.86e-03	16	148	2	C1257877
Disease	refractive error, age at onset, Myopia	CACNA1D FLT1 PCBP3 TFAP2B PZP	2.95e-03	193	148	5	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Libman-Sacks Disease	PCNX3 ITGAM DEF6	3.12e-03	58	148	3	C0242380
Disease	pre-eclampsia (is_marker_for)	FLT1 ITGAM PML	3.12e-03	58	148	3	DOID:10591 (is_marker_for)
Disease	Astrocytosis	ITGA2 ITGA4	3.23e-03	17	148	2	C3887640
Disease	ulcerative colitis (is_implicated_in)	CYP24A1 ABCB1	3.23e-03	17	148	2	DOID:8577 (is_implicated_in)
Disease	Vascular Diseases	MYLK AHR	3.23e-03	17	148	2	C0042373
Disease	Gliosis	ITGA2 ITGA4	3.23e-03	17	148	2	C0017639
Disease	phosphatidylcholine 36:4 measurement	RIPOR2 SIL1	3.63e-03	18	148	2	EFO_0010382
Disease	Carcinoma of bladder	ATM NOTCH2	3.63e-03	18	148	2	C0699885
Disease	Adenocarcinoma of lung (disorder)	FLT1 XRCC5 AHR PRKDC ATM	3.90e-03	206	148	5	C0152013
Disease	urolithiasis	CYP24A1 BCAS1 TFAP2B	3.94e-03	63	148	3	MONDO_0024647
Disease	Pheochromocytoma	DDC NF1	4.04e-03	19	148	2	C0031511
Disease	fish consumption measurement	TBC1D5 ADGRB3 NF1	4.12e-03	64	148	3	EFO_0010139
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	KRT18 ACADVL ABCB1	4.30e-03	65	148	3	DOID:0080208 (biomarker_via_orthology)
Disease	Drug-Induced Liver Disease	FLT1 KRT18 SERPINA6 ABCB1 AHR PRKDC PZP	4.40e-03	404	148	7	C0860207
Disease	Drug-Induced Acute Liver Injury	FLT1 KRT18 SERPINA6 ABCB1 AHR PRKDC PZP	4.40e-03	404	148	7	C3658290
Disease	Hepatitis, Toxic	FLT1 KRT18 SERPINA6 ABCB1 AHR PRKDC PZP	4.40e-03	404	148	7	C0019193
Disease	Chemically-Induced Liver Toxicity	FLT1 KRT18 SERPINA6 ABCB1 AHR PRKDC PZP	4.40e-03	404	148	7	C4279912
Disease	Chemical and Drug Induced Liver Injury	FLT1 KRT18 SERPINA6 ABCB1 AHR PRKDC PZP	4.40e-03	404	148	7	C4277682
Disease	Hepatitis, Drug-Induced	FLT1 KRT18 SERPINA6 ABCB1 AHR PRKDC PZP	4.40e-03	404	148	7	C1262760
Disease	Severe Combined Immunodeficiency	TCN2 PRKDC	4.47e-03	20	148	2	C0085110
Disease	Adenocarcinoma of prostate	EPHB2 ATM	4.47e-03	20	148	2	C0007112
Disease	Benign Neoplasm	ABCB1 AHR ATM	4.88e-03	68	148	3	C0086692
Disease	Neoplasms	ABCB1 AHR ATM	4.88e-03	68	148	3	C0027651
Disease	Neutropenia	TCN2 ABCB1	4.93e-03	21	148	2	C0027947

Protein segments in the cluster

Peptide	Gene	Start	Entry
CLLDNSSGFLAMNFQ	AHR	226	P35869
NFLAMVDNLQGDSGR	BACE2	76	Q9Y5Z0
LFNQAAGDAISDMLV	PGM3	411	O95394
ATTALSMQNNSVFGD	BRD9	386	Q9H8M2
LNQSSDELQLSMGNA	SERPINA3	126	P01011
NFMASELDDNAGLSR	ADGRB3	1386	O60242
MTLEEFANGAAQSDI	BTBD6	341	Q96KE9
AFTVTMQNLNEDDAG	CD300E	86	Q496F6
TDYMENGDLNQFLSA	DDR1	701	Q08345
NSQSEALSLEMAGLS	FAM220BP	56	B1ANY3
VNNINMDTDTSQLGF	MASTL	406	Q96GX5
DDGSREAMNNLSDFQ	DLL4	561	Q9NR61
NGSNEMLLAAASTDG	AASDH	1031	Q4L235
LAGQEGMQAVQNSDF	ATP8B3	956	O60423
LATMAGIDQSDFQLL	CEP78	546	Q5JTW2
AANTLDFGQNGAMDV	DYRK1A	686	Q13627
VMDNLLEALQSGAAF	DIAPH3	1061	Q9NSV4
SDGNFAMRASALQEA	DDC	211	P20711
VNSLFAGMDLTSLQN	CHD7	2746	Q9P2D1
FMGTLADVDNGNTNA	PPP1R13B	751	Q96KQ4
LLNLDNTDLFFSMAG	ATG2A	356	Q2TAZ0
SVEDANNSGMNLLDQ	TFAP2B	181	Q92481
LGNVNFSVSAEAMQS	PZP	871	P20742
ENREGLNMNLSSNSA	RBM44	631	Q6ZP01
GDNLSSMLLENLTDN	ODF2L	126	Q9ULJ1
FGAQDLAQQLMADAV	NIBAN3	466	Q86XR2
TDIFANAGNLEDLMS	ABCB1	76	P08183
NLMAAGQNLQSSERS	PAXIP1	311	Q6ZW49
MDNAASDLLAQGTSS	CACNA1F	1936	O60840
DTFALEFLMISNNGL	OR4D11	191	Q8NGI4
LLDAGADANAQDNMG	NOTCH2	1896	Q04721
MGSVNASANILNDIF	DGKK	1106	Q5KSL6
ASLNDAALAQMNSEV	FAM171A1	671	Q5VUB5
NLGDALDSSNSMQTI	KRT18	391	P05783
GMLSTSLADQDIFNA	LARGE1	326	O95461
FMGDNDNETLANVTS	MYLK	1661	Q15746
SSASSVDLGQMFINN	MGA	2551	Q8IWI9
NVGADENVAFALANM	LMOD3	291	Q0VAK6
DLSDNAIMSLQGNAF	LRIG3	416	Q6UXM1
DMNASAQGASATVLE	HERC2	1831	O95714
GNFQGLMEANVSLDL	MMRN2	756	Q9H8L6
AMFGQDLTSDNDILG	HERC1	2941	Q15751
MAAAAASASQDELNQ	ECPAS	1	Q5VYK3
FMENGSLDSFLRQND	EPHB2	701	P29323
ISDNNAASMLQVFDL	PCNX3	1466	Q9H6A9
TLNLGNENTDSSANM	KIAA0232	666	Q92628
AINSAEAERGFNLMN	KIAA1586	701	Q9HCI6
MANVGLQFQASAGDS	NPEPL1	1	Q8NDH3
DNQTALMALAVSFTN	PEX5	401	P50542
EDQFQLSLLAAMGNT	COPB1	686	P53618
DTLEDMNSQLNSFTG	COLEC12	281	Q5KU26
NSLNVDFLMLVGQSD	CYLC1	241	P35663
FAILAAMSIQGSANL	DPY19L1	506	Q2PZI1
MFSQAGLRSEAANGN	LRPPRC	506	P42704
GSNKDLMGLAINDSF	NLRP2	696	Q9NX02
MQIFNELDQAGSTLA	HMOX2	231	P30519
DTFALELFMISNNGL	OR4D6	191	Q8NGJ1
SAIAALSDINMDGFN	ITGA2	556	P17301
SQQAAAGNNMEDIFG	MPI	221	P34949
FMQSGNNEALDLTEL	PPP2R3A	296	Q06190
QQLLDFQETAGAMLA	EXOC7	511	Q9UPT5
EAQNLMGQSSGLDAS	PCBP3	276	P57721
AQLPANASLAAMAAA	POU2F1	581	P14859
LFNESTMAQLNGELQ	FAM171A2	621	A8MVW0
TFLMESAQDLDVGSN	PCDHB14	151	Q9Y5E9
MDSENTRDAQGQFLT	ATM	1006	Q13315
FNLGALSAMSNQQLE	ATRX	2311	P46100
NSNFLGLEMFDTQTQ	ATMIN	691	O43313
LLLGATEFQDSDQMG	IGSF10	896	Q6WRI0
MDNLQDTLEAASFLQ	KLHL13	161	Q9P2N7
SMLQATAEANNLAAV	ATL1	346	Q8WXF7
MSLLSNLEGAVSANQ	CENPF	1506	P49454
MLNTQVLGSSEDNFE	CYP24A1	416	Q07973
AADANFIMATGQALA	CACNA1S	1801	Q13698
RNSEAAMLQELNFGA	PRMT5	101	O14744
SQALNGDSDSEDMLN	BRWD1	2011	Q9NSI6
NSMFNDTLELFLIGN	TMEM30A	176	Q9NV96
DSNGNSMLSNQDAFR	DEF6	106	Q9H4E7
MAGGLANLQDLENTT	MAST2	1676	Q6P0Q8
TLMLNVSLFNAGDDA	ITGA4	656	P13612
LESQMQERNNAGFLS	CYBB	461	P04839
MSGSFELSVQDLNDL	DUSP3	1	P51452
AVGLNDGSFLMANAD	EML5	1056	Q05BV3
LDTGQMAFTLAQLES	CCDC192	61	P0DO97
QNAMGSQDSLLEITF	NOS1AP	366	O75052
QAAAIAENNNSIMSF	BCAS1	276	O75363
IDEMESAASTLLNGN	CACNA1D	2096	Q01668
LEEMGIADLFTNQAN	SERPINA6	316	P08185
EFNQLAMANSEGSEA	CNOT6	301	Q9ULM6
DDSGLELDNNNAAMA	RNF2	201	Q99496
SLDLGFNDLTDLQSM	LRRC43	226	Q8N309
MDGDNQSENSQFLLL	OR1D4	1	P47884
MDGDNQSENSQFLLL	OR1D5	1	P58170
AANQGQIAEAFNMAA	PDHA2	196	P29803
SDNAASLAVQAFLQM	MTX2	36	O75431
LTEMAASSQGNFEGN	FUNDC2	36	Q9BWH2
QNNMAFLALSNLDAA	SLC35A1	101	P78382
NMDTLLANQAGLDAF	RGS21	21	Q2M5E4
FDSANVDQAVAGAMA	ALDH5A1	316	P51649
NEDNSQLEMLGFSAD	PRUNE2	1811	Q8WUY3
QDAVSSMNLFDLGGQ	PUF60	281	Q9UHX1
DFMLALSLQNEGQAS	TRAFD1	241	O14545
FLQQAASNQLDSLMG	TRAFD1	341	O14545
NLVSQMALSEQEFSG	SYNE1	2946	Q8NF91
DFSLNSAISQLMGLS	LARS2	746	Q15031
MQVQSALAFLGTEND	NCOA7	461	Q8NI08
NNGTDLLADENFLMV	TAF1	391	P21675
ENADKAAFLMGINSS	MYH15	391	Q9Y2K3
DAMTQALQEQDSAFG	PML	241	P29590
LVNLAFAEASMAAFN	TACR1	71	P25103
MDVLAEANGTFALNL	SERPINB6	1	P35237
MDNAQDLLSFGGLQV	SIL1	216	Q9H173
FQAVMQANLTASSEG	SHISAL1	76	Q3SXP7
MDALQLANSAFAVDL	SERPINB5	1	P36952
IVAADDNQMAQGSLF	SI	1711	P14410
SFGMTLLGNFQLTND	TMEM150C	111	B9EJG8
GFNLDTENAMTFQEN	ITGAM	16	P11215
LNKNMEGAAAAAAAA	HOXA13	31	P31271
NGSSSQQMDDLFDIL	MRTFA	741	Q969V6
FNLSSLASQNEGMDD	RIPOR2	466	Q9Y4F9
DLISANMENALASIG	SPTLC1	301	O15269
ASLQDGAFQNALMIS	TCN2	276	P20062
LLNSAGNEFTQDQMG	ACTL7A	256	Q9Y615
SANMDQGATDFQIEA	ACADVL	401	P49748
EFNQVAMANSDGSEA	CNOT6L	301	Q96LI5
ELFISGDELMNQSQG	TULP4	1411	Q9NRJ4
QDLSKAMSQDGASQF	UGP2	6	Q16851
ESFGNNMVDNLDLFS	ZNF182	161	P17025
DNFNTAMQVLRDAGD	MTREX	341	P42285
TTISDNRFAMLANNN	NCAM2	156	O15394
QFAKSLAMLGSSEDN	SNX1	346	Q13596
DAFQQGKADLSAMSA	SERPINB9	291	P50453
AVGLSNLQFVDMNSS	SLC23A1	441	Q9UHI7
LNQMNLSSYGEDLLD	PYROXD1	476	Q8WU10
LMNDFSAALNNFQAV	STX12	106	Q86Y82
LINTGQAMDSSDNSE	SP3	296	Q02447
DMSNAGDFLNDNAVE	WDHD1	331	O75717
QMNLFADSLAGDISN	ROBO3	11	Q96MS0
SLQGFTAAQMGNEAV	TNKS	621	O95271
LRSQDMNDGLQNSLA	TIGD4	486	Q8IY51
MNDGLQNSLADLENF	TIGD4	491	Q8IY51
VLAMSNLLNANVDSG	NF1	1146	P21359
QLSQAAGLGASQMLD	PRRC2B	2056	Q5JSZ5
NVLGFSAALSTNIMD	SLC35E2B	221	P0CK96
VDMTLDANTANNFLL	RFPL2	186	O75678
DAFTENMAGENQLLE	PRKDC	1921	P78527
QFGQDPSAMAALAAE	ZNF821	366	O75541
QISFLQGQLNDLDAM	TBC1D5	591	Q92609
NADSQNEGLLTMEQF	TSNAXIP1	486	Q2TAA8
NEESFILDADSNMGN	FLT1	486	P17948
GSQQADFLDALIVSM	XRCC5	101	P13010
MNLNGENLENSGSTL	N4BP2	196	Q86UW6
ALDRFNAMNSALASD	MYZAP	156	P0CAP1
NAMNSALASDSIGLQ	MYZAP	161	P0CAP1
DLAENMVSQNDGSFI	NECTIN1	496	Q15223