Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

VLDLR DCHS2 FAT4 AOC1 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 NUCB1 PPP2R3B PCDHA2 CUBN RYR1 FAT1 DST CELSR3 PCDHGB4 PLA2G4F CDH13

3.18e-0874913521GO:0005509
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

DCHS2 FAT4 CEACAM5 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.67e-1118713214GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

DCHS2 FAT4 CEACAM5 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.41e-0831313214GO:0098742
GeneOntologyBiologicalProcesscell-cell adhesion

DCHS2 FAT4 CEACAM5 ANK3 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 AKNA PCDHA2 TEK CD200R1 FAT1 TNFSF11 KLHL25 CELSR3 BHLHA15 TLN1 PCDHGB4 NFAT5 CDH13

3.29e-07107713223GO:0098609
GeneOntologyBiologicalProcessmicrotubule bundle formation

NUMA1 CFAP65 FSIP2 MTCL1 DNAH8 HYDIN JHY

4.16e-051451327GO:0001578
GeneOntologyBiologicalProcessmicrotubule-based movement

ANK3 ASH1L CFAP65 FSIP2 MET DST BSN DNAH8 HYDIN DDX4 JHY KIF22

7.93e-0549313212GO:0007018
GeneOntologyCellularComponentapical part of cell

OTOA VLDLR FAT4 CEACAM5 MYO7B NUMA1 CUBN TEK FAT1 KL CSPG4 KCNMA1 MTCL1 PATJ

3.54e-0559213714GO:0045177
GeneOntologyCellularComponentcell surface

OTOA VLDLR CEACAM5 ANK3 NRDC ADAM20 MYO18A CUBN TEK CD200R1 MET P4HB TLN1 CSPG4 KCNMA1 STRC BSN ENG CDH13 STRCP1

3.77e-05111113720GO:0009986
GeneOntologyCellularComponentprotein phosphatase type 2A complex

PPP2R2D PPP2R3B PPP2R2C

2.09e-04181373GO:0000159
DomainCadherin_CS

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

8.73e-1310913313IPR020894
DomainCADHERIN_1

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.40e-1211313313PS00232
DomainCadherin

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.40e-1211313313PF00028
DomainCADHERIN_2

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.57e-1211413313PS50268
Domain-

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.57e-12114133132.60.40.60
DomainCA

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.76e-1211513313SM00112
DomainCadherin-like

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

1.97e-1211613313IPR015919
DomainCadherin

DCHS2 FAT4 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 FAT1 CELSR3 PCDHGB4 CDH13

2.46e-1211813313IPR002126
DomainCadherin_tail

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

1.74e-10371338PF15974
DomainCadherin_CBD

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

1.74e-10371338IPR031904
DomainCadherin_C

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHGB4

1.74e-08421337IPR032455
DomainCadherin_C_2

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHGB4

1.74e-08421337PF16492
DomainCadherin_2

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

1.92e-08651338PF08266
DomainCadherin_N

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

1.92e-08651338IPR013164
DomainStereocilin-rel

OTOA STRC

1.50e-0431332IPR026664
DomainLAM_G_DOMAIN

FAT4 FAT1 CELSR3 CSPG4

1.50e-04381334PS50025
DomainLaminin_G_2

FAT4 FAT1 CELSR3 CSPG4

1.84e-04401334PF02210
DomainLamG

FAT4 FAT1 CELSR3 CSPG4

2.68e-04441334SM00282
DomainEGF_3

VLDLR FAT4 ADAM20 CUBN TEK ADAM22 FAT1 CELSR3

2.83e-042351338PS50026
DomainPP2A_PR55_CS

PPP2R2D PPP2R2C

2.99e-0441332IPR018067
DomainPP2A_PR55

PPP2R2D PPP2R2C

2.99e-0441332IPR000009
DomainPR55_2

PPP2R2D PPP2R2C

2.99e-0441332PS01025
DomainPR55_1

PPP2R2D PPP2R2C

2.99e-0441332PS01024
DomainEGF-like_dom

VLDLR FAT4 ADAM20 CUBN TEK ADAM22 FAT1 CELSR3

4.17e-042491338IPR000742
DomainEGF_1

VLDLR FAT4 ADAM20 CUBN TEK ADAM22 FAT1 CELSR3

4.88e-042551338PS00022
DomainEGF-like_CS

VLDLR FAT4 ADAM20 CUBN TEK ADAM22 FAT1 CELSR3

5.69e-042611338IPR013032
Domain-

FAT4 FAT1 CELSR3 CSPG4 WDFY3

5.89e-049513352.60.120.200
DomainEGF_2

VLDLR FAT4 ADAM20 CUBN TEK ADAM22 FAT1 CELSR3

6.29e-042651338PS01186
DomainZnf_FYVE_PHD

ASH1L SHPRH ZFYVE26 WDFY3 BSN UHRF2

6.48e-041471336IPR011011
DomainASX_HYDROXYL

VLDLR FAT4 CUBN FAT1 CELSR3

7.44e-041001335PS00010
DomainLaminin_G

FAT4 FAT1 CELSR3 CSPG4

7.74e-04581334IPR001791
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR FAT4 CUBN FAT1 CELSR3

9.68e-041061335IPR000152
DomainHelicase_C

DDX59 DDX51 DHX33 SHPRH DDX4

1.01e-031071335PF00271
DomainHELICc

DDX59 DDX51 DHX33 SHPRH DDX4

1.01e-031071335SM00490
DomainHelicase_C

DDX59 DDX51 DHX33 SHPRH DDX4

1.05e-031081335IPR001650
DomainHELICASE_CTER

DDX59 DDX51 DHX33 SHPRH DDX4

1.10e-031091335PS51194
DomainHELICASE_ATP_BIND_1

DDX59 DDX51 DHX33 SHPRH DDX4

1.10e-031091335PS51192
DomainDEXDc

DDX59 DDX51 DHX33 SHPRH DDX4

1.10e-031091335SM00487
DomainHelicase_ATP-bd

DDX59 DDX51 DHX33 SHPRH DDX4

1.14e-031101335IPR014001
DomainEGF

VLDLR FAT4 CUBN TEK ADAM22 FAT1 CELSR3

1.49e-032351337SM00181
DomainPapD-like

CFAP65 HYDIN

1.75e-0391332IPR008962
DomainEGF_CA

VLDLR FAT4 CUBN FAT1 CELSR3

1.81e-031221335SM00179
DomainDEAD/DEAH_box_helicase_dom

DDX59 DDX51 DHX33 DDX4

1.83e-03731334IPR011545
DomainDEAD

DDX59 DDX51 DHX33 DDX4

1.83e-03731334PF00270
DomainEGF-like_Ca-bd_dom

VLDLR FAT4 CUBN FAT1 CELSR3

1.94e-031241335IPR001881
Domain-

DDX59 MYO7B SMC6 MYO18A DDX51 MSH3 DHX33 EEF1A2 TRANK1 SHPRH DNAH8 HYDIN DDX4

2.59e-03746133133.40.50.300
DomainP-loop_NTPase

DDX59 MYO7B SMC6 MYO18A DDX51 MSH3 DHX33 EEF1A2 TRANK1 SHPRH DNAH8 HYDIN DDX4 KIF22

2.91e-0384813314IPR027417
DomainEGF_CA

VLDLR FAT4 CUBN FAT1

3.33e-03861334PF07645
DomainConA-like_dom

FAT4 RYR1 FAT1 CELSR3 CSPG4 WDFY3

4.85e-032191336IPR013320
DomainEGF_Ca-bd_CS

VLDLR FAT4 CUBN FAT1

5.11e-03971334IPR018097
DomainGrowth_fac_rcpt_

VLDLR FAT4 CUBN TEK FAT1

5.20e-031561335IPR009030
DomainEGF_CA

VLDLR FAT4 CUBN FAT1

5.49e-03991334PS01187
DomainDisintegrin_CS

ADAM20 ADAM22

5.66e-03161332IPR018358
DomainAcyl_Trfase/lysoPLipase

PLA2G4F PNPLA7

6.38e-03171332IPR016035
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 CELSR3 PCDHGB4

1.29e-1172138910380929
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 CELSR3 PCDHGB4

3.42e-1180138910716726
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

3.03e-1068138811230163
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ARHGEF19 NDOR1 INTS1 NAGLU AKNA CEP192 MED13L MAPKAPK5 RYR1 PRR12 FAT1 KLHL25 DST CELSR3 TLN1 CSPG4 USP7 AP1G2 AKAP13 ZFYVE26 WDFY3 KLHL17

4.94e-1011051382235748872
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

6.05e-1074138810817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

8.37e-1077138810835267
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

DDX59 NRDC MAT2A NUCB1 NUMA1 NCOA4 RRM1 XRCC5 MET SEC24D FAT1 DST P4HB GCLM TAX1BP1 AKAP13 MTCL1 CROCC ENG CNOT1 KIF22

4.60e-0812971382133545068
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

FAT4 PCDHGB3 INTS1 NAGLU SYNC XRCC5 RYR1 EEF1A2 TNFSF11 DST TLN1 AKAP13 MTCL1 CNOT1 NXF1

2.61e-077361381529676528
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 NUCB1 ASH1L NUMA1 MYO18A XRCC5 OGDH EEF1A2 DST P4HB CSPG4 VPS35 PCDHGB4 BSN SNX9 DNAH8

2.68e-0714421382135575683
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

NRIP1 ANK3 RBBP4 TDH ASH1L PAQR5 CEP192 XRCC5 OGDH EEF1A2 PPP2R2C SHPRH KCNMA1 AKAP13 PNPLA7 PATJ CROCC SNX9 NFAT5 CNOT1 SLC2A11

4.52e-0714891382128611215
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ANK3 PPP2R2D ASH1L NUMA1 XRCC5 OGDH RYR1 EEF1A2 DST P4HB TLN1 USP7 AKAP13 CNOT1 HYDIN

8.29e-078071381530575818
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

VLDLR GAD2 NRIP1 DCHS2 ANK3 MAT2A NUCB1 ASH1L SYNC MSH3 MED13L ADAM22 HMG20A EEF1A2 DST CELSR3 SLF2 USP7 WDFY3

8.42e-0712851381935914814
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

DLGAP4 MYO18A DHX33 ADAM22 KL DST VPS35 PRRT3 KCNMA1 BSN

1.37e-063471381017114649
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CCDC22 RBBP4 MAT2A NUMA1 DDX51 MSH3 DHX33 RRM1 XRCC5 DST P4HB TLN1 VPS35 SF3A3 USP7 AP1G2 AKAP13 WDFY3 NXF1

1.80e-0613531381929467282
Pubmed

Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

DCHS2 FAT4 FAT1

2.11e-067138316059920
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ANK3 NRDC DLGAP4 MYO18A OGDH ADAM22 EEF1A2 GPD1L PPP2R2C DST P4HB PTPRZ1 TLN1 VPS35 USP7 BSN CROCC CNOT1 GOT1

4.05e-0614311381937142655
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

RBBP4 INTS1 NUMA1 MSH3 XRCC5 HMG20A SHPRH USP7 CNOT1 KIF22

4.24e-063941381027248496
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC22 ANK3 PPP2R2D NAGLU PPP2R3B CEP192 FAM171A1 P4HB PTPRZ1 PRIM1 KCNMA1 USP7 EFR3B PDP2 CNOT1 KIF22

4.49e-0610491381627880917
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ANK3 MAT2A NUMA1 RRM1 XRCC5 FAM171A1 DST GCLM TLN1 EFR3B PATJ SNX9 CNOT1

5.31e-067081381339231216
Pubmed

Phosphoinositide-specific phospholipase C β 1b (PI-PLCβ1b) interactome: affinity purification-mass spectrometry analysis of PI-PLCβ1b with nuclear protein.

NUMA1 RRM1 EEF1A2 TLN1 VPS35 CNOT1 NXF1

5.36e-06169138723665500
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RBBP4 SMC6 INTS1 NUMA1 MSH3 XRCC5 HMG20A FSIP2 SHPRH USP7 UHRF2 KIF22

6.03e-066081381236089195
Pubmed

Zinc Finger Protein 618 Regulates the Function of UHRF2 (Ubiquitin-like with PHD and Ring Finger Domains 2) as a Specific 5-Hydroxymethylcytosine Reader.

XRCC5 USP7 UHRF2

7.19e-0610138327129234
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

INTS1 NUMA1 SYNC XRCC5 HMG20A PRR12 USP7

7.26e-06177138726206133
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

XRCC5 OGDH P4HB TLN1 VPS35 PDP2 MTCL1

8.71e-06182138731067453
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RBBP4 INTS1 NUMA1 DDX51 XRCC5 DST P4HB TLN1 USP7 SNX9 CNOT1 NXF1

1.23e-056531381222586326
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

ANK3 RBBP4 MAT2A MYO18A XRCC5 EEF1A2 DST P4HB TLN1 VPS35 SF3A3 USP7 PATJ SNX9 CNOT1 GOT1

1.39e-0511491381635446349
Pubmed

Receptor-type protein tyrosine phosphatase beta (RPTP-beta) directly dephosphorylates and regulates hepatocyte growth factor receptor (HGFR/Met) function.

MET PTPRZ1

1.56e-052138221454675
Pubmed

RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcript in secondary glioblastomas.

MET PTPRZ1

1.56e-052138225135958
Pubmed

Nardilysin convertase regulates the function of the maxi-K channel isoform mK44 in human myometrium.

NRDC KCNMA1

1.56e-052138219118164
Pubmed

NuMA1 promotes axon initial segment assembly through inhibition of endocytosis.

ANK3 NUMA1

1.56e-052138231727776
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

1.56e-052138234910522
Pubmed

The nuclear factor of activated T cells 5 (NFAT5) contributes to the renal corticomedullary differences in gene expression.

NDOR1 NFAT5

1.56e-052138236433977
Pubmed

Redox-regulated peptide transfer from the transporter associated with antigen processing to major histocompatibility complex class I molecules by protein disulfide isomerase.

P4HB NXF1

1.56e-052138221299467
Pubmed

Increased expression of plasminogen activator inhibitor-1 with fibrin deposition in a murine model of aging, "Klotho" mouse.

KL SERPINE1

1.56e-052138212536348
Pubmed

High-sensitive clinical diagnostic method for PTPRZ1-MET and the characteristic protein structure contributing to ligand-independent MET activation.

MET PTPRZ1

1.56e-052138233645009
Pubmed

A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes.

MET SERPINE1

1.56e-052138231054988
Pubmed

Genetic deletion or tyrosine phosphatase inhibition of PTPRZ1 activates c-Met to up-regulate angiogenesis and lung adenocarcinoma growth.

MET PTPRZ1

1.56e-052138237260355
Pubmed

Voltage-dependent Ca2+ channels, not ryanodine receptors, activate Ca2+-dependent BK potassium channels in human retinal pigment epithelial cells.

RYR1 KCNMA1

1.56e-052138219096717
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

1.56e-052138211687802
Pubmed

Enhanced expression and phosphorylation of the MET oncoprotein by glioma-specific PTPRZ1-MET fusions.

MET PTPRZ1

1.56e-052138225935522
Pubmed

PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.

KL SERPINE1

1.56e-052138224778222
Pubmed

Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.

DCHS2 FAT4

1.56e-052138215003449
Pubmed

Tumour exosomes from cells harbouring PTPRZ1-MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma.

MET PTPRZ1

1.56e-052138228504721
Pubmed

NG2 and phosphacan are present in the astroglial scar after human traumatic spinal cord injury.

PTPRZ1 CSPG4

1.56e-052138219604403
Pubmed

Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling.

TNFSF11 VPS35

1.56e-052138223509071
Pubmed

Generation of a conditional knockout allele for the NFAT5 gene in mice.

NDOR1 NFAT5

1.56e-052138225601839
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

FAT4 CEACAM5 AOC1 CILP NUCB1 NAGLU CUBN OMD GPD1L KL TLN1 CSPG4 PATJ CDH13 GOT1

2.44e-0510701381523533145
Pubmed

A Dynamic Splicing Program Ensures Proper Synaptic Connections in the Developing Cerebellum.

NUMA1 AP1G2 NFAT5 KIF22

2.85e-0544138432492419
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

RBBP4 NUMA1 MSH3 XRCC5 OGDH P4HB USP7

2.87e-05219138731353912
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

RBBP4 NUMA1 XRCC5 P4HB TLN1 VPS35 SF3A3 USP7 SNX9 CNOT1

2.99e-054941381026831064
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANK3 DLGAP4 NUMA1 XRCC5 ADAM22 EEF1A2 FAM171A1 DST TAX1BP1 KCNMA1 MTCL1 WDFY3 BSN CNOT1

3.11e-059631381428671696
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NRIP1 DCHS2 ANK3 NUMA1 TRANK1 VPS35 SHPRH USP7 CNOT1 HYDIN

3.14e-054971381036774506
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NRIP1 PPP2R2D RBBP4 PRR12 ZFHX4 USP7 SNX9 NXF1 GOT1

3.22e-05398138935016035
Pubmed

Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.

ASH1L ZFHX4 WDFY3

3.30e-0516138316096065
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

NRDC MYO18A XRCC5 USP7 AKAP13 SNX9 GOT1

3.51e-05226138737839992
Pubmed

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.

GAD2 ANK3 DLGAP4 OGDH ADAM22 EEF1A2 GPD1L BSN GOT1

3.54e-05403138930562941
Pubmed

Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.

OTOA STRC STRCP1

3.99e-0517138320856818
Pubmed

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.

AOC1 NAGLU CUBN

3.99e-0517138321082674
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

MYO7B RBBP4 NUMA1 OGDH DST VPS35 USP7

4.38e-05234138736243803
Pubmed

Long-term prognostic significance of neoangiogenesis in breast carcinomas: comparison of Tie-2/Tek, CD105, and CD31 immunocytochemical expression.

TEK ENG

4.68e-053138214991534
Pubmed

Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5.

AKAP13 NFAT5

4.68e-053138219211510
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

4.68e-053138230801007
Pubmed

Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone.

NDOR1 NFAT5

4.68e-053138228803730
Pubmed

The histone methyltransferase ASH1L protects against bone loss by inhibiting osteoclastogenesis.

ASH1L TNFSF11

4.68e-053138238431690
Pubmed

Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration.

NDOR1 TEK

4.68e-053138230788433
Pubmed

Type XVII collagen coordinates proliferation in the interfollicular epidermis.

KL SERPINE1

4.68e-053138228693719
Pubmed

RANK- and c-Met-mediated signal network promotes prostate cancer metastatic colonization.

MET TNFSF11

4.68e-053138224478054
Pubmed

NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms.

NDOR1 NCOA4

4.68e-053138230630985
Pubmed

Two-dimensional gel electrophoresis, protein electroblotting and microsequencing: a direct link between proteins and genes.

RBBP4 P4HB

4.68e-05313821699755
Pubmed

PAI-1 is a critical regulator of FGF23 homeostasis.

KL SERPINE1

4.68e-053138228924605
Pubmed

Plasminogen activator inhibitor 1 functions as a urokinase response modifier at the level of cell signaling and thereby promotes MCF-7 cell growth.

VLDLR SERPINE1

4.68e-053138211266465
Pubmed

Genomic analysis of mouse retinal development.

DOHH RBBP4 MAT2A SMC6 KLHL25 DST ZFHX4 TAX1BP1 CARF ZFYVE26 WDFY3 PNPLA7 BSN CROCC

4.99e-0510061381415226823
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NRDC RBBP4 MAT2A SMC6 NUMA1 MSH3 XRCC5 OGDH P4HB PRIM1 TLN1 VPS35 SF3A3 USP7 BSN CNOT1 NXF1

5.23e-0514251381730948266
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

NUMA1 MSH3 RRM1 XRCC5 EEF1A2 P4HB TLN1 USP7

5.74e-05332138832786267
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

NRDC RBBP4 NUMA1 SYNC RRM1 XRCC5 TLN1 VPS35 SF3A3 BSN SNX9

6.28e-056531381133742100
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

NRDC RBBP4 MAT2A NUCB1 RRM1 XRCC5 EEF1A2 SEC24D P4HB GCLM TLN1 VPS35 SF3A3 USP7 CROCC CNOT1 GOT1

6.75e-0514551381722863883
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

GAD2 PCDHGC5 PCDHA2 PCDHGB4

7.96e-0557138432633719
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAT4 RBBP4 NUCB1 NAGLU RRM1 ADAM22 MET FAT1 CELSR3 P4HB CSPG4 VPS35 SERPINE1 ENG CDH13

8.96e-0512011381535696571
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

9.33e-054138218849963
Pubmed

Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin.

KL TNFSF11

9.33e-054138215564564
Pubmed

Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice.

NDOR1 CUBN

9.33e-054138229032953
Pubmed

DNA damage triggers Golgi dispersal via DNA-PK and GOLPH3.

MYO18A XRCC5

9.33e-054138224485452
Pubmed

The PTPRZ1-MET/STAT3/ISG20 axis in glioma stem-like cells modulates tumor-associated macrophage polarization.

MET PTPRZ1

9.33e-054138238685521
Pubmed

Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.

LFNG MET

9.33e-054138222624713
Pubmed

S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology.

SERPINE1 ENG

9.33e-054138218974388
Pubmed

Fibroblast growth factor 23 and 25(OH)D levels are related to abdominal obesity and cardiovascular risk in patients with polycystic ovarian syndrome.

KL TNFSF11

9.33e-054138231709849
Pubmed

Do serum angiopoietin-1, angiopoietin-2, and their receptor Tie-2 and 4G/5G variant of PAI-1 gene have a role in the pathogenesis of preeclampsia?

TEK SERPINE1

9.33e-054138221849906
Pubmed

The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins.

NUMA1 HMG20A

9.33e-054138223707952
Pubmed

PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-β1-receptor signaling.

KL SERPINE1

9.33e-054138234110636
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

ANK3 XRCC5 FAT1 CELSR3 ZFHX4 AKAP13 MTCL1 NXF1

1.03e-04361138826167880
Pubmed

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool.

DCHS2 FAT4 FAT1

1.16e-0424138326116661
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

ASH1L CCDC168 FSIP2 DST CNOT1

1.36e-04123138526912792
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

FAT1 DST P4HB TLN1 CSPG4 ENG CDH13

1.50e-04285138721423176
Pubmed

DNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links.

SMC6 SLF2

1.55e-045138225931565
Pubmed

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.

AKAP13 NFAT5

1.55e-045138229298866
Pubmed

Cytogenetic characterization of radiosensitive mouse mutants.

EEF1A2 DST

1.55e-04513821720867
Pubmed

FOXL2 interaction with different binding partners regulates the dynamics of ovarian development.

USP7 DDX4

1.55e-045138238517962
Pubmed

Molecular mechanisms underlying postoperative peritoneal tumor dissemination may differ between a laparotomy and carbon dioxide pneumoperitoneum: a syngeneic mouse model with controlled respiratory support.

MET SERPINE1

1.55e-045138218622550
Pubmed

Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly.

FAT4 FAT1

1.55e-045138230862798
Pubmed

Simultaneous quantitative assessment of two distinct cell lineages with a nuclear-localized dual genetic reporter.

NDOR1 CSPG4

1.55e-045138232668281
InteractionRYK interactions

FAT4 ANK3 XRCC5 FAM171A1 MET DST CELSR3 CSPG4 VPS35 NXF1

1.68e-0621213510int:RYK
InteractionTOP3B interactions

ARHGEF19 NDOR1 INTS1 NAGLU AKNA CEP192 MSH3 MED13L XRCC5 MAPKAPK5 RYR1 PRR12 FAT1 KLHL25 DST CELSR3 TLN1 CSPG4 USP7 AP1G2 AKAP13 ZFYVE26 WDFY3 CNOT1 KLHL17

1.35e-05147013525int:TOP3B
Cytoband5q31

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

2.45e-0911513885q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

TRPC7 PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

3.34e-072981389chr5q31
GeneFamilyClustered protocadherins

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHA2 PCDHGB4

1.26e-096493820
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2D PPP2R3B PPP2R2C

5.73e-0515933696
GeneFamilyCadherin related

DCHS2 FAT4 FAT1

8.50e-051793324
GeneFamilyDEAD-box helicases

DDX59 DDX51 DDX4

1.31e-0342933499
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500

OGFRL1 VLDLR ANK3 RBBP4 PAQR5 MSH3 FAM171A1 KL AKAP13 PATJ NFAT5 GOT1

1.02e-0540213512gudmap_developingKidney_e15.5_anlage of loop of Henle_500
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA FAT4 MYO7B FAT1 TRANK1 ZFHX4 HYDIN

1.76e-0618413872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA FAT4 MYO7B FAT1 TRANK1 ZFHX4 HYDIN

1.76e-061841387ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA FAT4 MYO7B FAT1 TRANK1 ZFHX4 HYDIN

1.76e-0618413872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAQR5 MET PPP2R2C DST KCNMA1 PATJ SNX9

1.96e-061871387f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAQR5 MET PPP2R2C DST KCNMA1 PATJ SNX9

2.10e-061891387e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellcritical-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

OGFRL1 LYPD6B NCOA4 MET SEC24D PTPRZ1 NFAT5

2.68e-061961387dbf14f5851c2b779a8b35e820c4584ea9096e49d
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANK3 MET SEC24D FAT1 AP1G2 STRC PATJ

2.86e-061981387285f729140b1df029c24f6ca1d2438470ac51794
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NRIP1 CEP192 DST CARF SERPINE1 ENG

1.79e-051751386334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

NUMA1 MYO18A ADAM22 FAM171A1 DST WDFY3

1.90e-051771386e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DCHS2 MET FAT1 BHLHA15 PATJ HYDIN

1.97e-051781386544379f5a6145429762258d426b876bb36c112f5
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LYPD6B ARHGEF19 ANK3 ZFHX4 PTPRZ1 CSPG4

2.09e-0518013861e819c5c87704ec6535dfeaae56561895e239d07
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

FAT4 MED13L OMD TEK ADAM22 ZFHX4

2.37e-05184138667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellCV-Healthy-7|Healthy / Virus stimulation, Condition and Cluster

OGFRL1 ADAM22 CARF ENG SLC2A11 JHY

2.44e-0518513861979d189c204f4c2893e3170a514ee7d5523406c
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF19 FAT1 PTPRZ1 CSPG4 KCNMA1 CDH13

2.59e-051871386218c9b4f28499389c43005d9626af2ac01066027
ToppCellfacs-Kidney-nan-3m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 PAQR5 NCOA4 OGDH KL DST

2.59e-051871386208686e6ebc9f3a774bcbe89274457ac9449f90e
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 CD200R1 DST SERPINE1 PNPLA7 PATJ

2.59e-051871386f20e7a1751694390f535ffb27b97e887220f8695
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAQR5 MET DST KCNMA1 PATJ SNX9

2.59e-05187138677886f99c229610abd28c4c370d2c7d1536c9782
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF19 FAT1 PTPRZ1 CSPG4 KCNMA1 CDH13

2.59e-051871386c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP PCDHGB3 OMD ZFHX4 PTPRZ1 SERPINE1

2.67e-051881386c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CILP PCDHGB3 OMD ZFHX4 PTPRZ1 SERPINE1

2.67e-0518813861cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

LYPD6B CEACAM5 ANK3 MET PTPRZ1 PATJ

2.84e-05190138651ca9ef4df3220487152fcf684147730637c7cc1
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

ANK3 DST AKAP13 PATJ CDH13 GOT1

2.84e-051901386fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

ANK3 GREB1L DST AKAP13 PATJ CDH13

2.92e-05191138625f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 ASH1L CUBN MED13L AKAP13 PATJ

3.01e-051921386e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell(1)_Osterolineage_cells|World / Cell class and subclass of bone marrow stroma cells in homeostatis

VLDLR OMD FAT1 TNFSF11 ZFHX4 PTPRZ1

3.10e-051931386035eeea9f77c4bf9cd85f07fa791b6c857be76b5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LYPD6B PAQR5 MET FAT1 AKAP13 NFAT5

3.19e-05194138646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAT4 LYPD6B PAQR5 ADAM22 DST ZFHX4

3.19e-051941386b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LYPD6B PAQR5 MET FAT1 AKAP13 NFAT5

3.19e-051941386abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ANK3 PAQR5 CUBN MET FAT1 PATJ

3.19e-0519413867002937e8903e037332a215d00fbc7c7843b33f2
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FAT4 LYPD6B PAQR5 ADAM22 DST ZFHX4

3.28e-0519513860e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LYPD6B ANK3 MET FAT1 ZFHX4 PATJ

3.38e-051961386c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

CILP FAT1 PTPRZ1 SERPINE1 KCNMA1 CDH13

3.38e-05196138624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 DST P4HB TLN1 VPS35 CDH13

3.57e-05198138622559b161e67b49fe8028bfaf861e069063599f5
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-3|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

PCDHGB7 CILP OMD TEK ZFHX4 CSPG4

3.67e-05199138607b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FAT4 MAT2A DHX33 MED13L FAT1 ZFHX4

3.67e-051991386358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ANK3 MET SEC24D FAT1 AP1G2 PATJ

3.78e-052001386e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 MET FAT1 DST PTPRZ1 CDH13

3.78e-0520013869da214f756a03516eaafde00289b90f69623b9f3
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_3|367C / Donor, Lineage, Cell class and subclass (all cells)

PCDHGB7 PCDHGB6 PPP2R3B RYR1 KLHL17

5.51e-051311385aeeb5718b3a7122492ad2659d5c8112f60839ff3
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOC1 NAGLU CUBN KL SNX9

8.91e-05145138547a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

CCDC168 CD200R1 TNFSF11 DST ASB11

1.01e-041491385d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCellMS-CD4-CD8_1|MS / Condition, Cell_class and T cell subcluster

VLDLR ADAM22 EEF1A2 GREB1L PNPLA7

1.05e-0415013857dc95c58b98d8c4c6c49fb1a03ec6ac24fb41f54
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM22 CELSR3 BHLHA15 AP1G2 DNAH8

1.29e-0415713850fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

ANK3 GPD1L MET FAT1 AKAP13

1.29e-04157138531d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ZFHX4 PTPRZ1 KCNMA1 HYDIN

1.41e-041601385c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NRIP1 CEACAM5 NAGLU PPP2R2C TNFSF11

1.41e-0416013855d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO7B ZFHX4 PTPRZ1 KCNMA1 HYDIN

1.41e-04160138525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellBL-critical-LOC-Myeloid-Basophil|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

LYPD6B ADAM22 LFNG TNFSF11 DNAH8

1.50e-04162138525ec9df914445b4daae4fd28fd0e60b64797c46d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

ANK3 GPD1L MET FAT1 AKAP13

1.54e-041631385e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellmild-Myeloid-Eosinophils|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

LYPD6B LFNG CD200R1 TNFSF11 PATJ

1.54e-0416313857c57d541a88e9afa079e95b8a6ecdea60a0c6aaa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCDHGA1 RRM1 TEK FAM171A1 CDH13

1.68e-0416613858e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|368C / Donor, Lineage, Cell class and subclass (all cells)

NRIP1 TNFSF11 KLHL25 PRRT3 PDP2

1.83e-0416913850d96c0b4fd26fbc0bf44ff7bed2936eebcc55b74
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

VLDLR LYPD6B GPD1L MET GOT1

1.83e-041691385aec97583b23112060437b619cb429dc32f29285f
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD200R1 PPP2R2C AP1G2 BSN DNAH8

1.88e-04170138571e5e27c3c4e6cc8dc9b063bd51c21c049f54416
ToppCellfacs-Heart-LV-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD200R1 PPP2R2C AP1G2 BSN DNAH8

1.88e-041701385255bbbd00d0e17510c5a8c5faa43ed90d887a9de
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INTS1 PRR12 PRIM1 PDP2 KIF22

1.88e-041701385b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

OTOA ANK3 NAGLU PLA2G4F CDH13

1.93e-041711385e59afa0a773dca3b9c208d17510ea55703b42598
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD2 TRPC7 CFAP65 MET CELSR3

1.93e-041711385fa5cc720bd0045d0307439be547b41d56def5b43
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

LYPD6B LFNG CD200R1 TNFSF11 PATJ

1.93e-0417113855c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCelldroplet-Lung-nan-21m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR5 ZC3H12B CD200R1 CFAP65 SEC24D

2.04e-0417313858fb32a9f2dbec16de840d55b4db7e7718f5a2a7a
ToppCelldroplet-Lung-nan-21m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR5 ZC3H12B CD200R1 CFAP65 SEC24D

2.04e-041731385f663571aaae2365660a8b526c355f4bd1a124a74
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNC PTPRZ1 PRIM1 SERPINE1 CDH13

2.09e-0417413859f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP PCDHGA2 OMD ZFHX4 PTPRZ1

2.09e-0417413859c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TEK KL SERPINE1 ENG JHY

2.09e-0417413856b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CILP PCDHGA2 OMD ZFHX4 PTPRZ1

2.09e-041741385bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PRSS54 FAT4 CCDC168 CSPG4 CDH13

2.15e-041751385f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFSF11 PTPRZ1 CSPG4 CDH13 KIF22

2.20e-04176138575412d58438d71c49a6096bb2ef12b7f349653d8
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

XRCC5 PRR12 GCLM SHPRH KLHL17

2.20e-04176138591ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

OMD TEK EEF1A2 MET SERPINE1

2.20e-04176138552af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

ANK3 CUBN MET KLHL25 PATJ

2.20e-04176138536f77d878a53b30465b0dea8333a3865dba75613
ToppCellSevere-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ANK3 SMC6 RYR1 CD200R1 TLN1

2.32e-041781385b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 RRM1 ADAM22 CD200R1 SERPINE1

2.32e-041781385de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 RYR1 EEF1A2 PRRT3 BSN

2.32e-041781385a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAD2 RYR1 EEF1A2 PRRT3 BSN

2.32e-0417813851bddbc083c36657bd6910f7466126ab325e88176
ToppCellEndothelial-A-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

FAT4 OMD TEK FAM171A1 SERPINE1

2.32e-0417813852f2602b9305d55f25afa9861dd6c6347ae179337
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

LYPD6B ANK3 MET PTPRZ1 PATJ

2.38e-041791385d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FAT4 TEK MET ENG CDH13

2.38e-0417913852a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PAQR5 CUBN MET FAT1 PATJ

2.45e-041801385358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO7B PAQR5 CUBN FAT1 PATJ

2.45e-041801385864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PCDHGA2 FAM171A1 ENG CDH13

2.51e-0418113854df7972f88117108698efd06b124b232f8588981
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM1 SEC24D KLHL25 EFR3B KIF22

2.51e-041811385b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM1 SEC24D KLHL25 EFR3B KIF22

2.51e-041811385c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCelldroplet-Lung-LUNG-30m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 CD200R1 DST SERPINE1 PNPLA7

2.51e-0418113858fcdab61fad2efd324d2b27c58f5a594f1dc15de
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGB7 ZC3H12B PPP2R2C DST CDH13

2.51e-0418113854ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCelldroplet-Liver-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 PCDHGA2 FAM171A1 ENG CDH13

2.51e-041811385cbb530566893281289026bfd93adf721decd4ca3
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

ANK3 MET FAT1 PTPRZ1 PATJ

2.57e-041821385759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 CD200R1 DST SERPINE1 PNPLA7

2.57e-041821385be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOHH PPP2R3B OMD GPD1L SF3A3

2.64e-041831385ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR5 PPP2R2C KL DST CDH13

2.64e-04183138512e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellBasal|World / shred by cell class for mouse tongue

PPP2R2C DST TLN1 CSPG4 CDH13

2.64e-041831385c6729a207526ff4aa48176207b9353176f631fea
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO7B CUBN FAT1 PATJ HYDIN

2.64e-0418313856878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCelldroplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 CD200R1 SERPINE1 PNPLA7 PATJ

2.64e-041831385ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCellCV-Healthy-7|CV / Virus stimulation, Condition and Cluster

OGFRL1 ADAM22 CARF SLC2A11 JHY

2.71e-0418413850e5cc77aaa73ceb791f8be7456177577fd2e5586
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like-C|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PCDHGC5 PCDHGB3 PCDHGA2 PCDHGA1 PCDHGB4

2.71e-041841385629cfed10e1112cf30f6a828ce9efbbc6b207789
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-I_cells_(CCK+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAD2 TRPC7 CFAP65 CELSR3 GCLM

2.71e-0418413851e6f86f9e379cd9f453f6b7185f681b44eb63e09
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CUBN SEC24D CRISP1 BHLHA15 JHY

2.71e-04184138542cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

ANK3 GREB1L DST AKAP13 CDH13

2.71e-041841385ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 GPD1L MET FAT1 EFR3B

2.71e-041841385102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellP28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TEK PPP2R2C DST TAX1BP1 ENG

2.71e-0418413858ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCelldroplet-Lung-nan-3m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA4 CD200R1 SERPINE1 PNPLA7 PATJ

2.71e-0418413853261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHGB6 TEK FAM171A1 ENG CDH13

2.77e-041851385742350093d90f96735dc73e3360cdd749bae63fd
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

VLDLR CEACAM5 DLGAP4 NUCB1 PAQR5 OGDH EEF1A2 MET TLN1

2.64e-0619313794343_DN
DrugMeprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A

OGFRL1 INTS1 OGDH MET KLHL25 AKAP13 NFAT5 CNOT1 JHY

3.12e-0619713793544_DN
DrugFlucytosine [2022-85-7]; Up 200; 31uM; HL60; HT_HG-U133A

GAD2 ANK3 CILP DDX51 EEF1A2 KL ZFHX4 EFR3B JHY

3.39e-0619913793073_UP
Drugisosulfan blue

CEACAM5 MET UHRF2

7.33e-0671373CID000004695
Drugaminobutyrate

OGDH RYR1 KL GCLM STRC DDX4 GOT1

8.27e-061201377CID000006657
Druggenistein; Up 200; 10uM; HL60; HT_HG-U133A

GAD2 CILP INTS1 DDX51 EEF1A2 SEC24D CSPG4 KCNMA1

2.53e-0519613786194_UP
DrugAzapropazone [13539-59-8]; Up 200; 13.4uM; HL60; HT_HG-U133A

DLGAP4 INTS1 LFNG CELSR3 PTPRZ1 AP1G2 ENG JHY

2.63e-0519713783143_UP
DrugTobramycin [32986-56-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

AOC1 DDX51 ADAM22 RYR1 SEC24D ZFHX4 SLC2A11 JHY

2.72e-0519813782841_UP
DrugRacecadotril [81110-73-8]; Down 200; 10.4uM; MCF7; HT_HG-U133A

VLDLR DLGAP4 NUCB1 ADAM22 HMG20A MET KLHL25 USP7

2.72e-0519813782774_DN
DrugButamben [94-25-7]; Down 200; 20.6uM; MCF7; HT_HG-U133A

CEACAM5 DLGAP4 NUMA1 KLHL25 TLN1 KCNMA1 WDFY3 PATJ

2.82e-0519913786093_DN
Diseasechildhood trauma measurement, alcohol consumption measurement

PCDHGC5 PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHGB4

4.14e-08711377EFO_0007878, EFO_0007979
Diseasemental development measurement

PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 PCDHGB4

9.89e-08251375EFO_0008230
DiseaseSarcosine measurement

PCDHGB3 PCDHGA2 PCDHGA1 PCDHGB4

3.68e-06231374EFO_0021668
DiseaseCole-Carpenter syndrome (is_implicated_in)

SEC24D P4HB

2.14e-0521372DOID:0060438 (is_implicated_in)
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

2.14e-0521372DOID:0110471 (implicated_via_orthology)
DiseaseCole Carpenter syndrome

SEC24D P4HB

2.14e-0521372C1862178
Diseasecreatinine measurement

CUBN LFNG RYR1 CD200R1 EEF1A2 CELSR3 SLF2 CSPG4 PCDHGB4 KCNMA1 PNPLA7 BSN UHRF2 NFAT5 CDH13

6.28e-0599513715EFO_0004518
Diseasehematocrit

VLDLR NRIP1 AOC1 ASH1L LFNG CD200R1 PRR12 MET FAT1 BSN CROCC UHRF2 NFAT5 ENG HYDIN

7.50e-05101113715EFO_0004348
Diseasearteriovenous malformation (is_implicated_in)

TEK ENG

1.28e-0441372DOID:11294 (is_implicated_in)
Diseaseamyloidosis (is_implicated_in)

SERPINE1 GOT1

1.28e-0441372DOID:9120 (is_implicated_in)
DiseasePost-Traumatic Osteoporosis

KL TNFSF11 P4HB TLN1

1.89e-04611374C0751406
DiseaseOsteoporosis, Senile

KL TNFSF11 P4HB TLN1

1.89e-04611374C0029459
DiseaseOsteoporosis, Age-Related

KL TNFSF11 P4HB TLN1

1.89e-04611374C0001787
DiseaseOsteoporosis

KL TNFSF11 P4HB TLN1

2.14e-04631374C0029456
Diseaseenergy expenditure

MTCL1 PATJ CDH13

2.64e-04271373EFO_0005109
Diseasetumor necrosis factor ligand superfamily member 6, soluble form measurement

CELSR3 BSN

4.43e-0471372EFO_0020797
Diseasesubstance-related disorder (implicated_via_orthology)

KCNMA1 CDH13

4.43e-0471372DOID:303 (implicated_via_orthology)
DiseaseManic

GAD2 ANK3 TRANK1 DNAH8

4.86e-04781374C0338831
Diseasesleep duration, circadian rhythm, excessive daytime sleepiness measurement, insomnia measurement

CD200R1 PATJ

5.88e-0481372EFO_0004354, EFO_0005271, EFO_0007875, EFO_0007876
DiseaseProstatic Neoplasms

NAGLU ASH1L MSH3 MET P4HB SERPINE1 USP7 AKAP13 PATJ CDH13

6.26e-0461613710C0033578
DiseaseMalignant neoplasm of prostate

NAGLU ASH1L MSH3 MET P4HB SERPINE1 USP7 AKAP13 PATJ CDH13

6.26e-0461613710C0376358
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

TEK RYR1 MET KCNMA1 AKAP13

6.52e-041481375C0279702
Diseaseautism spectrum disorder (implicated_via_orthology)

DLGAP4 ASH1L MET WDFY3 NAA16

7.35e-041521375DOID:0060041 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

ASH1L MED13L EEF1A2 WDFY3

9.43e-04931374C1535926
Diseasemean platelet volume

AOC1 PCDHGC5 NRDC PCDHGB7 PCDHGB6 PCDHGB3 PCDHGA2 PCDHGA1 NUMA1 LFNG TRANK1 PCDHGB4 USP7

9.59e-04102013713EFO_0004584
Diseaseendometrial carcinoma (is_implicated_in)

MSH3 CDH13

1.37e-03121372DOID:2871 (is_implicated_in)
DiseasePathological accumulation of air in tissues

PPP2R2C KL

1.37e-03121372C0013990
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D PPP2R2C

1.37e-03121372DOID:1441 (implicated_via_orthology)
Diseaserenal fibrosis (biomarker_via_orthology)

SERPINE1 ENG

1.37e-03121372DOID:0050855 (biomarker_via_orthology)
Diseasepolycystic ovary syndrome (is_marker_for)

NCOA4 SERPINE1

1.37e-03121372DOID:11612 (is_marker_for)
Diseasefocal segmental glomerulosclerosis (biomarker_via_orthology)

VLDLR SERPINE1

1.37e-03121372DOID:1312 (biomarker_via_orthology)
Diseasesmoking status measurement, ulcerative colitis

XRCC5 MAPKAPK5

1.61e-03131372EFO_0000729, EFO_0006527
DiseaseHypercalcemia

KL TNFSF11

1.61e-03131372C0020437
DiseaseMilk-Alkali Syndrome

KL TNFSF11

1.61e-03131372C0026141
Diseasenon-alcoholic fatty liver disease

ARHGEF19 AKNA FAM171A1 MET KCNMA1

1.64e-031821375EFO_0003095
DiseaseAlzheimer disease, polygenic risk score

PCDHGA2 PCDHGA1 MAPKAPK5 HMG20A FSIP2 FAM171A1 DST NFAT5 HYDIN

1.71e-035861379EFO_0030082, MONDO_0004975
Diseasepulse pressure measurement

NRIP1 DLGAP4 PCDHA2 MED13L OMD MET TRANK1 ZFHX4 SF3A3 AKAP13 NFAT5 CNOT1 HYDIN SLC2A11 CDH13

2.09e-03139213715EFO_0005763
Diseasefacial morphology

GAD2 MYO18A FAM171A1

2.15e-03551373EFO_0004743
Diseasespine bone mineral density

DCHS2 ANK3 TNFSF11 KCNMA1

2.34e-031191374EFO_0007701
Diseaseurate measurement, bone density

DDX59 DHX33 OGDH HMG20A FSIP2 KCNMA1 DNAH8 CDH13 JHY

2.47e-036191379EFO_0003923, EFO_0004531
Diseaserenal fibrosis (implicated_via_orthology)

SERPINE1 ENG

2.78e-03171372DOID:0050855 (implicated_via_orthology)
Diseasepuberty onset measurement

TRPC7 SLF2 NFAT5 JHY

2.79e-031251374EFO_0005677
DiseaseSarcomatoid Renal Cell Carcinoma

RYR1 MET KCNMA1 AKAP13

3.04e-031281374C1266043
DiseaseChromophobe Renal Cell Carcinoma

RYR1 MET KCNMA1 AKAP13

3.04e-031281374C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

RYR1 MET KCNMA1 AKAP13

3.04e-031281374C1266044
DiseasePapillary Renal Cell Carcinoma

RYR1 MET KCNMA1 AKAP13

3.04e-031281374C1306837
DiseaseRenal Cell Carcinoma

RYR1 MET KCNMA1 AKAP13

3.04e-031281374C0007134
Diseaseobesity (implicated_via_orthology)

DCHS2 FAT4 DHX33 MED13L ZFHX4

3.37e-032151375DOID:9970 (implicated_via_orthology)
Diseasediet measurement, HOMA-B

NFAT5 CDH13

3.47e-03191372EFO_0004469, EFO_0008111
Diseasesmoking cessation

ANK3 OGDH KCNMA1 BSN NFAT5 NAA16

4.20e-033251376EFO_0004319
DiseaseManic Disorder

GAD2 ANK3 TRANK1

4.44e-03711373C0024713

Protein segments in the cluster

PeptideGeneStartEntry
HPAENIIAIAATNNL

PPP2R2C

421

Q9Y2T4
VIEAVVQSVNLNPEH

ASH1L

1896

Q9NR48
QHQATALLEVQASEP

CSPG4

1111

Q6UVK1
IENVQHVINFDLPST

DDX4

606

Q9NQI0
VIPNLIEHSTVQQFH

ADAM20

571

O43506
QNELSVDHSDPVILN

CEACAM5

396

P06731
FQEALQESIPDIQAH

GCLM

226

P48507
PHFLQAIESVNVVEN

FAT4

891

Q6V0I7
ENISHNTQDILIPNV

AKAP13

1106

Q12802
LNNAFQALREVIPHV

BHLHA15

91

Q7RTS1
PQLTHVDQASFQVDA

ADAM22

81

Q9P0K1
FHQSVQEIFEVNNLP

AP1G2

766

O75843
HPVDNVIAVAATNNL

PPP2R2D

431

Q66LE6
ILLANNVNIDHEVPQ

ASB11

181

Q8WXH4
PPVVFEQFLHNNENI

AOC1

646

P19801
FHINQPAEFIEDQSI

CDH13

36

P55290
FHLEPQAQATQVSDV

CCDC22

301

O60826
QASLIPQLFGHEQQV

DLGAP4

456

Q9Y2H0
LQHEAAVPQLAAALA

DOHH

216

Q9BU89
QAPNAILEVHVLFLE

ENG

56

P17813
ALVDSVAQGIPFQQH

NAGLU

681

P54802
DLPNVQEEIVNIHNA

CRISP1

36

P54107
AHILLQVADINDNAP

PCDHGA2

436

Q9Y5H1
QEDFVPFLQDVVNTH

PPP2R3B

231

Q9Y5P8
FNIIDHSPVVQDPFQ

MTCL1

1766

Q9Y4B5
LEAVVENPLNIFHVI

PCDHGB6

106

Q9Y5F9
AQIHVLVTDANDNAP

PCDHGB4

226

Q9UN71
LEAVVENPLNIFHVI

PCDHGB7

106

Q9Y5F8
QPLDHEEVELLQFQV

PCDHA2

521

Q9Y5H9
SIDQIPQVFHEQGIL

PAQR5

11

Q9NXK6
HAVFLEPGQVVQEQA

ARHGEF19

156

Q8IW93
VAFTIPSLQAAVENH

OTOA

81

Q7RTW8
VLVHLQDENDNAPVF

FAT1

1751

Q14517
EFQAIIPAVNSHIQS

MSH3

651

P20585
ISNPAATHQDIDFLI

GAD2

561

Q05329
FILHEALVENTIPNI

OGFRL1

261

Q5TC84
HQPVADALIEIFTNQ

FAM171A1

46

Q5VUB5
ENLQQVPTSELHEQV

LFNG

316

Q8NES3
VEIAQHQPIYLINEE

MED13L

181

Q71F56
THPNIVQIIEVFANS

MAPKAPK5

71

Q8IW41
VNVEIVFLHNISPNL

KCNMA1

436

Q12791
HQQALVQLTDVQPSE

JHY

571

Q6NUN7
LLQFLDQAVAHDPQT

INTS1

1261

Q8N201
QDADLLVFVIPHQFI

GPD1L

86

Q8N335
HSIILANPQDNENFI

HMG20A

321

Q9NP66
VVAQQFHETLEPLNE

DST

5501

Q03001
QISDAVLDAHLQQDP

MAT2A

36

P31153
NFHEAVDQSLVEQVP

CFAP65

1691

Q6ZU64
VQPLVINLNAQEHTF

BSN

1711

Q9UPA5
DVQTIPIQIIDNHSA

CARF

671

Q8N187
PIQIIDNHSALIEEN

CARF

676

Q8N187
HPFILNLQEDQIENL

DDX59

171

Q5T1V6
ILFQLHQEPVNESFQ

FSIP2

941

Q5CZC0
TNIILAEIFDFQIHP

FSIP2

4731

Q5CZC0
NVVAFLNELPKTQHD

NXF1

461

Q9UBU9
LNELPKTQHDVNSFV

NXF1

466

Q9UBU9
HVFVLDENDNAPAVL

PCDHGC5

551

Q9Y5F6
LIQEQAASPNAEIHI

KIF22

536

Q14807
NHLAENNVFGIVPLA

MYO18A

616

Q92614
VNEVDNPNVALNHTA

NAA16

841

Q6N069
IVPSLLFNLQHVEEA

EFR3B

196

Q9Y2G0
LLFEVHNIENASPAT

DNAH8

2241

Q96JB1
NIVDAANNHSAPEVL

NRIP1

876

P48552
HLQVLVTPEVTLFQN

CD200R1

146

Q8TD46
HNQLPLVIEFTEQTA

P4HB

231

P07237
ELFQTANLEINQAHP

PTPRZ1

1291

P23471
FFHVTVLIQDINDNP

PCDHGB3

116

Q9Y5G1
PVNTIIIHEDFDNNS

PRSS54

111

Q6PEW0
AEQDPNVQVDHLNLL

NUCB1

121

Q02818
PLNHQDSQELQVEFV

PLA2G4F

146

Q68DD2
IPTQNLDLDNETFHI

GREB1L

656

Q9C091
HNEPVVLQVFVGNDS

NFAT5

321

O94916
IVFVQLQEGEHVFQP

PNPLA7

161

Q6ZV29
DVVLIQPSNSAAHVQ

NDOR1

246

Q9UHB4
QNHLVIASVQLPNDD

RBBP4

76

Q09028
AQIVILDVNDHNPTF

DCHS2

1606

Q6V1P9
QEVLLNSPLQEEHNF

NCOA4

566

Q13772
LVPETIHDELQQSFQ

PRIM1

246

P49642
AVAHAQSLVEAQPNV

OGDH

106

Q02218
DDFHLQLSPEQINEV

PDP2

71

Q9P2J9
PQGEQIQINFTHVEL

CUBN

741

O60494
QHGADTVQLPQLVDA

DYRK4

471

Q9NR20
QLEAQVVVLEQSHSP

CROCC

1926

Q5TZA2
FQIQIAHLDPENITL

HYDIN

1471

Q4G0P3
NLSIINAPTLHIQEF

SLC2A11

31

Q9BYW1
HDIDPQALDQLVQFA

KLHL17

136

Q6TDP4
TVNFQDNLHPEVLEL

KLHL25

86

Q9H0H3
FNDNNSIHPLVEVQR

DPH7

71

Q9BTV6
VDHIDQTPGFSLQQL

DDX51

351

Q8N8A6
EAAQFTSQVIILNHP

EEF1A2

336

Q05639
IHQEAPSSQDILVFL

DHX33

281

Q9H6R0
NDLENAPEFSIVVLH

GOT1

176

P17174
QEFQTPEQATELVHQ

AKNA

431

Q7Z591
QLLLQHNVPVDDVTN

ANK3

351

Q12955
LPEHSVLQNINFVEA

CEP192

2011

Q8TEP8
IDLEFNHPQIFIVEN

KL

401

Q9UEF7
LHLNVNTGFQEESIP

CCDC168

5211

Q8NDH2
VHITVLDENDNAPQF

CELSR3

531

Q9NYQ7
LQAAAPSHEFQQVAL

LINC01554

46

Q52M75
VFVLPTHQNVIQFEL

RYR1

1551

P21817
LDSQELLQQEAVAPH

PRRT3

131

Q5FWE3
SFALEVQDHVFQIPA

C4orf19

171

Q8IY42
NSLHVADPVEAVLQL

NUMA1

16

Q14980
IFNLPNIVELSVGHN

OMD

276

Q99983
SLSDQEPLHVAQALQ

SERPINE1

331

P05121
LVTDINDNSPVFHQD

PCDHGA1

441

Q9Y5H4
SALNPELVQAVQHVV

MET

1056

P08581
PALQEVQQVHQDILA

SYNC

206

Q9H7C4
HPVISESEVFQQFLN

SNX9

341

Q9Y5X1
EVPLQTSNFAHVIFQ

TAX1BP1

6

Q86VP1
QETQSIQVDVQHPAL

SHPRH

286

Q149N8
EDVPNASNLQVSVLH

SLF2

1031

Q8IX21
LQDALHTFPQLQVEQ

PRR12

1906

Q9ULL5
NFLQLSPHQIQALED

STRC

881

Q7RTU9
ESQSVIHNLLDQIPD

SEC24D

531

O94855
LVNHLPLAVNNDTSE

CILP

1046

O75339
LNAPEHVLETINFQT

CNOT1

2001

A5YKK6
AIEAFQLTPQQQHLI

UHRF2

686

Q96PU4
ETHVDPIQLQALQNA

ZFHX4

3186

Q86UP3
TQPEHALDLQLAVAN

WDFY3

866

Q8IZQ1
FIDQSQSLNIHIAEP

RRM1

701

P23921
ENDQILAINHTPLDQ

PATJ

181

Q8NI35
VQEISHLIEPLANAA

TLN1

1706

Q9Y490
IIQVFPDEFHLQTLN

VPS35

266

Q96QK1
DIFVNILTHNLAEPA

NRDC

726

O43847
LIAILDHFNIQVDNP

SMC6

171

Q96SB8
DHFNIQVDNPVSVLT

SMC6

176

Q96SB8
ILLDNVAAEQAHNLP

ACP6

251

Q9NPH0
PNVIDTGHNFAVINI

TEK

451

Q02763
PHTADAQQLAALIVA

ZC3H12B

816

Q5HYM0
EAQPFAHLTINATDI

TNFSF11

161

O14788
QVFQVAAELLQHPEH

UNQ6494/PRO21346

121

Q6UXR6
PNTAHFANVTQIEDA

SF3A3

441

Q12874
NFLQLSPHQIQALED

STRCP1

881

A6NGW2
QPIEFGAHQVILVAN

TRANK1

1531

O15050
EVLQAVTDHDIPQQL

USP7

526

Q93009
FDENNHFIVPISQIL

TSPAN19

46

P0C672
EAEAHPVQIQTQLLQ

ZFYVE26

1121

Q68DK2
LINHIEQFLDTNETP

XRCC5

616

P13010
LDVAAEHNLQLFVPS

TDH

151

Q8IZJ6
IVEAILNHPAFAQGQ

TRPC7

121

Q9HCX4
NDAQDIIVYHELVQP

VLDLR

686

P98155
NVELPTNHTNAVFAV

LYPD6B

141

Q8NI32
IFTLALQHPALQDEV

MYO7B

1696

Q6PIF6