Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontubulin binding

NUSAP1 DAG1 DST DCTN1 MAPT PSRC1 CAMSAP3

6.82e-05428487GO:0015631
GeneOntologyMolecularFunctionmicrotubule binding

NUSAP1 DST DCTN1 MAPT PSRC1 CAMSAP3

9.13e-05308486GO:0008017
GeneOntologyMolecularFunctiondystroglycan binding

DAG1 AGRN

3.68e-0412482GO:0002162
GeneOntologyMolecularFunctionactin binding

DAG1 PPP1R18 DST MAPT CAMSAP3 MYO1F

9.65e-04479486GO:0003779
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 MUC17 AGRN COL27A1

1.07e-03188484GO:0005201
GeneOntologyMolecularFunctioncytoskeletal protein binding

NUSAP1 DAG1 PPP1R18 DST DCTN1 MAPT PSRC1 CAMSAP3 MYO1F

1.08e-031099489GO:0008092
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

CELSR1 DCTN1 MAPT AGRN PSRC1 PPFIA1 SLC4A2 CAMSAP3 MYO1F

6.42e-06579489GO:0051493
GeneOntologyBiologicalProcesspositive regulation of Rac protein signal transduction

AUTS2 AGRN TNS3

9.42e-0618483GO:0035022
GeneOntologyBiologicalProcessregulation of microtubule polymerization

DCTN1 MAPT PSRC1 CAMSAP3

2.00e-0569484GO:0031113
GeneOntologyBiologicalProcessmicrotubule-based process

NUSAP1 DAG1 CC2D2A TMEM108 DST DCTN1 MAPT AGRN PSRC1 DNAH14 CAMSAP3

2.41e-0510584811GO:0007017
GeneOntologyBiologicalProcessmicrotubule anchoring

DAG1 DCTN1 CAMSAP3

2.62e-0525483GO:0034453
GeneOntologyBiologicalProcessaxonal transport

TMEM108 DST DCTN1 MAPT

2.78e-0575484GO:0098930
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

NUSAP1 DAG1 CC2D2A DST DCTN1 MAPT AGRN PSRC1 CAMSAP3

3.62e-05720489GO:0000226
GeneOntologyBiologicalProcessaxonogenesis

AUTS2 DAG1 SEMA4F HSPG2 TSC2 DST MAPT AGRN

4.39e-05566488GO:0007409
GeneOntologyBiologicalProcesspositive regulation of neuromuscular junction development

DCTN1 AGRN

5.28e-055482GO:1904398
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

DCTN1 MAPT AGRN PSRC1 CAMSAP3

5.44e-05176485GO:0070507
GeneOntologyBiologicalProcesscell morphogenesis

AUTS2 DAG1 SEMA4F HSPG2 TMEM108 TSC2 DST MAPT AGRN COL27A1 SIPA1L3

7.27e-0511944811GO:0000902
GeneOntologyBiologicalProcessregulation of Rac protein signal transduction

AUTS2 AGRN TNS3

7.35e-0535483GO:0035020
GeneOntologyBiologicalProcessaxo-dendritic transport

TMEM108 DST DCTN1 MAPT

7.94e-0598484GO:0008088
GeneOntologyBiologicalProcessneuron projection morphogenesis

AUTS2 DAG1 SEMA4F HSPG2 TMEM108 TSC2 DST MAPT AGRN

8.33e-05802489GO:0048812
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization

DCTN1 MAPT PSRC1

8.69e-0537483GO:0031116
GeneOntologyBiologicalProcesstransport along microtubule

TMEM108 DST DCTN1 MAPT CAMSAP3

9.27e-05197485GO:0010970
GeneOntologyBiologicalProcessregulation of protein localization to synapse

DAG1 TMEM108 MAPT

9.42e-0538483GO:1902473
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

AUTS2 DAG1 SEMA4F HSPG2 TMEM108 TSC2 DST MAPT AGRN

9.78e-05819489GO:0120039
GeneOntologyBiologicalProcessneuron development

AUTS2 DAG1 SEMA4F HSPG2 PCARE TMEM108 TSC2 DST MAPT AGRN PAK4 CAMSAP3

9.82e-0514634812GO:0048666
GeneOntologyBiologicalProcessgrowth

AUTS2 DAG1 SEMA4F TMEM108 MBD5 MAPT AGRN PSRC1 COL27A1 GJD4 PAK4

9.84e-0512354811GO:0040007
GeneOntologyBiologicalProcesscell projection morphogenesis

AUTS2 DAG1 SEMA4F HSPG2 TMEM108 TSC2 DST MAPT AGRN

1.04e-04826489GO:0048858
GeneOntologyBiologicalProcessaxon development

AUTS2 DAG1 SEMA4F HSPG2 TSC2 DST MAPT AGRN

1.06e-04642488GO:0061564
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

DCTN1 MAPT PSRC1 CAMSAP3

1.16e-04108484GO:0031110
GeneOntologyBiologicalProcesspositive regulation of microtubule polymerization or depolymerization

DCTN1 MAPT PSRC1

1.27e-0442483GO:0031112
GeneOntologyBiologicalProcessneuron projection development

AUTS2 DAG1 SEMA4F HSPG2 TMEM108 TSC2 DST MAPT AGRN PAK4 CAMSAP3

1.40e-0412854811GO:0031175
GeneOntologyBiologicalProcessmicrotubule polymerization

DCTN1 MAPT PSRC1 CAMSAP3

1.58e-04117484GO:0046785
GeneOntologyBiologicalProcesscytoskeleton-dependent intracellular transport

TMEM108 DST DCTN1 MAPT CAMSAP3

1.73e-04225485GO:0030705
GeneOntologyBiologicalProcessregulation of organelle organization

NUSAP1 TSC2 CELSR1 DCTN1 MAPT AGRN PSRC1 PPFIA1 SLC4A2 CAMSAP3 MYO1F

2.05e-0413424811GO:0033043
GeneOntologyBiologicalProcessdevelopmental growth

AUTS2 DAG1 SEMA4F TMEM108 MBD5 MAPT AGRN COL27A1 GJD4

2.18e-04911489GO:0048589
GeneOntologyBiologicalProcessregulation of neuromuscular junction development

DCTN1 AGRN

2.36e-0410482GO:1904396
GeneOntologyBiologicalProcessmicrotubule-based transport

TMEM108 DST DCTN1 MAPT CAMSAP3

2.97e-04253485GO:0099111
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

AUTS2 DAG1 SEMA4F HSPG2 TSC2 DST MAPT AGRN

3.01e-04748488GO:0048667
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

TSC2 DST DCTN1 SIPA1L3 CAMSAP3

3.19e-04257485GO:0007163
GeneOntologyBiologicalProcesscell junction organization

DAG1 TMEM108 TSC2 DST DCTN1 MAPT AGRN PPFIA1 CAMSAP3

3.58e-04974489GO:0034330
GeneOntologyBiologicalProcessRac protein signal transduction

AUTS2 AGRN TNS3

3.69e-0460483GO:0016601
GeneOntologyBiologicalProcesscellular response to brain-derived neurotrophic factor stimulus

TMEM108 MAPT

4.74e-0414482GO:1990416
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

HSPG2 DCTN1 MAPT PSRC1 PPFIA1 CAMSAP3

5.11e-04438486GO:1902903
GeneOntologyBiologicalProcessregulation of microtubule-based process

DCTN1 MAPT AGRN PSRC1 CAMSAP3

5.81e-04293485GO:0032886
GeneOntologyBiologicalProcessmicrotubule polymerization or depolymerization

DCTN1 MAPT PSRC1 CAMSAP3

6.25e-04168484GO:0031109
GeneOntologyBiologicalProcessestablishment of cell polarity

TSC2 DCTN1 SIPA1L3 CAMSAP3

7.60e-04177484GO:0030010
GeneOntologyBiologicalProcessmicrotubule-based movement

TMEM108 DST DCTN1 MAPT DNAH14 CAMSAP3

9.48e-04493486GO:0007018
GeneOntologyBiologicalProcesssynapse organization

DAG1 TMEM108 TSC2 DCTN1 MAPT AGRN PPFIA1

9.73e-04685487GO:0050808
GeneOntologyBiologicalProcessDNA replication checkpoint signaling

MDC1 CAMSAP3

9.81e-0420482GO:0000076
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

AUTS2 TSC2 AGRN SIPA1L3 TNS3

1.03e-03333485GO:0051056
GeneOntologyBiologicalProcesspositive regulation of small GTPase mediated signal transduction

AUTS2 AGRN TNS3

1.28e-0392483GO:0051057
GeneOntologyBiologicalProcessneuron projection extension

AUTS2 SEMA4F TMEM108 MAPT

1.36e-03207484GO:1990138
GeneOntologyBiologicalProcessretrograde axonal transport

TMEM108 DST

1.42e-0324482GO:0008090
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

AUTS2 TSC2 CELSR1 AGRN SIPA1L3 TNS3

1.48e-03538486GO:0007264
GeneOntologyBiologicalProcesssupramolecular fiber organization

HSPG2 DCTN1 MAPT PSRC1 PPFIA1 COL27A1 CAMSAP3 MYO1F

1.51e-03957488GO:0097435
GeneOntologyBiologicalProcessregulation of neurotransmitter receptor localization to postsynaptic specialization membrane

DAG1 TMEM108

1.54e-0325482GO:0098696
GeneOntologyBiologicalProcesspositive regulation of protein polymerization

DCTN1 MAPT PSRC1

1.73e-03102483GO:0032273
GeneOntologyCellularComponentanchoring junction

DAG1 HSPG2 HEPACAM DST PPFIA1 SIPA1L3 TNS3 MDC1 GJD4 PAK4 SLC4A2 CAMSAP3

1.47e-069764812GO:0070161
GeneOntologyCellularComponentfocal adhesion

DAG1 HSPG2 DST PPFIA1 TNS3 MDC1 PAK4 SLC4A2

5.61e-06431488GO:0005925
GeneOntologyCellularComponentcell-substrate junction

DAG1 HSPG2 DST PPFIA1 TNS3 MDC1 PAK4 SLC4A2

6.85e-06443488GO:0030055
GeneOntologyCellularComponentaxon

AUTS2 DAG1 HEPACAM TMEM108 TSC2 DST DCTN1 MAPT AGRN PPFIA1

2.82e-058914810GO:0030424
GeneOntologyCellularComponentsupramolecular fiber

NUSAP1 TLK2 DAG1 DST DCTN1 MAPT PSRC1 DNAH14 COL27A1 CAMSAP3 MYO1F

5.75e-0511794811GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

NUSAP1 TLK2 DAG1 DST DCTN1 MAPT PSRC1 DNAH14 COL27A1 CAMSAP3 MYO1F

6.11e-0511874811GO:0099081
GeneOntologyCellularComponentmicrotubule end

DST DCTN1 CAMSAP3

9.06e-0538483GO:1990752
GeneOntologyCellularComponentGolgi lumen

DAG1 HSPG2 MUC17 AGRN

1.14e-04109484GO:0005796
GeneOntologyCellularComponentbasement membrane

DAG1 HSPG2 DST AGRN

1.76e-04122484GO:0005604
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

NUSAP1 TLK2 DST DCTN1 MAPT PSRC1 DNAH14 CAMSAP3 MYO1F

1.79e-04899489GO:0099513
GeneOntologyCellularComponentmicrotubule

NUSAP1 DST DCTN1 MAPT PSRC1 DNAH14 CAMSAP3

2.00e-04533487GO:0005874
GeneOntologyCellularComponentcell-cell junction

DAG1 HEPACAM DST SIPA1L3 GJD4 PAK4 CAMSAP3

3.75e-04591487GO:0005911
GeneOntologyCellularComponentaxon cytoplasm

TMEM108 DST MAPT

5.13e-0468483GO:1904115
GeneOntologyCellularComponentcollagen-containing extracellular matrix

DAG1 HSPG2 DST MUC17 AGRN COL27A1

1.28e-03530486GO:0062023
GeneOntologyCellularComponentcytoplasmic region

TMEM108 DST DCTN1 MAPT CAMSAP3

1.37e-03360485GO:0099568
GeneOntologyCellularComponentcell cortex

DST DCTN1 DENND2B C2CD2L MYO1F

1.57e-03371485GO:0005938
GeneOntologyCellularComponentmicrotubule plus-end

DST DCTN1

1.88e-0328482GO:0035371
GeneOntologyCellularComponentneuron projection cytoplasm

TMEM108 DST MAPT

2.06e-03110483GO:0120111
GeneOntologyCellularComponentgrowth cone

AUTS2 TSC2 MAPT AGRN

2.39e-03245484GO:0030426
GeneOntologyCellularComponentsite of polarized growth

AUTS2 TSC2 MAPT AGRN

2.68e-03253484GO:0030427
GeneOntologyCellularComponentpostsynaptic density

SEMA4F TMEM108 TSC2 DST MAPT

3.65e-03451485GO:0014069
GeneOntologyCellularComponentextracellular matrix

DAG1 HSPG2 DST MUC17 AGRN COL27A1

3.73e-03656486GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

DAG1 HSPG2 DST MUC17 AGRN COL27A1

3.79e-03658486GO:0030312
GeneOntologyCellularComponentcilium

CC2D2A PCARE SSTR3 DCTN1 MAPT DNAH14 CAMSAP3

4.17e-03898487GO:0005929
GeneOntologyCellularComponentasymmetric synapse

SEMA4F TMEM108 TSC2 DST MAPT

4.63e-03477485GO:0032279
GeneOntologyCellularComponentaxonal growth cone

MAPT AGRN

4.80e-0345482GO:0044295
GeneOntologyCellularComponentglial cell projection

HEPACAM MAPT

5.23e-0347482GO:0097386
GeneOntologyCellularComponentpostsynaptic specialization

SEMA4F TMEM108 TSC2 DST MAPT

5.78e-03503485GO:0099572
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

TMEM108 DST MAPT CAMSAP3

5.98e-03317484GO:0032838
GeneOntologyCellularComponentneuron to neuron synapse

SEMA4F TMEM108 TSC2 DST MAPT

6.79e-03523485GO:0098984
GeneOntologyCellularComponentdynein complex

DCTN1 DNAH14

6.85e-0354482GO:0030286
GeneOntologyCellularComponentnuclear periphery

DAG1 SRRM1 MAPT

7.10e-03171483GO:0034399
GeneOntologyCellularComponentpostsynapse

DAG1 SEMA4F TMEM108 TSC2 DST MAPT PPFIA1

8.18e-031018487GO:0098794
MousePhenoabnormal neuromuscular synapse morphology

DAG1 HSPG2 DST DCTN1 MAPT AGRN

1.65e-0795376MP:0001053
MousePhenoabnormal somatic motor system morphology

DAG1 HSPG2 DST DCTN1 MAPT AGRN

1.98e-0798376MP:0001051
MousePhenoabnormal neurite morphology

HSPG2 HEPACAM TMEM108 TSC2 DST MBD5 MAPT AGRN CAMSAP3

1.65e-06442379MP:0008415
MousePhenoabnormal axon morphology

HSPG2 HEPACAM DST MAPT AGRN CAMSAP3

1.24e-05199376MP:0005404
MousePhenoabnormal synapse morphology

DAG1 HSPG2 DST DCTN1 MAPT AGRN

2.43e-05224376MP:0009538
MousePhenoabnormal somatic nervous system morphology

AUTS2 DAG1 CC2D2A HSPG2 PCARE CELSR1 DST DCTN1 MAPT AGRN CAMSAP3

4.52e-0510253711MP:0002752
MousePhenoabnormal chondrocyte physiology

HSPG2 COL27A1 TNS3

1.83e-0442373MP:0009780
MousePhenoabnormal cartilage physiology

HSPG2 COL27A1 TNS3

1.96e-0443373MP:0031306
MousePhenoparesis

DST MAPT AGRN

3.65e-0453373MP:0000754
MousePhenoabnormal embryonic growth/weight/body size

NUSAP1 TLK2 DAG1 CC2D2A HSPG2 RPRD2 TSC2 DST PPFIA1 COL27A1 PAK4

3.67e-0412953711MP:0002088
DomainLAM_G_DOMAIN

HSPG2 CELSR1 AGRN COL27A1

2.24e-0638464PS50025
DomainSEA

HSPG2 MUC17 AGRN

4.99e-0614463SM00200
DomainLaminin_G

HSPG2 CELSR1 AGRN COL27A1

1.24e-0558464IPR001791
DomainSEA

HSPG2 MUC17 AGRN

2.08e-0522463PF01390
DomainSEA

HSPG2 MUC17 AGRN

2.39e-0523463PS50024
DomainSEA_dom

HSPG2 MUC17 AGRN

2.39e-0523463IPR000082
DomainEGF_LAM_2

HSPG2 CELSR1 AGRN

5.42e-0530463PS50027
DomainEGF_LAM_1

HSPG2 CELSR1 AGRN

5.42e-0530463PS01248
DomainLaminin_EGF

HSPG2 CELSR1 AGRN

8.66e-0535463PF00053
DomainEGF_Lam

HSPG2 CELSR1 AGRN

8.66e-0535463SM00180
DomainLaminin_EGF

HSPG2 CELSR1 AGRN

1.11e-0438463IPR002049
DomainLamG

HSPG2 CELSR1 AGRN

1.73e-0444463SM00282
DomainRap_GAP

TSC2 SIPA1L3

2.64e-0410462PF02145
DomainRap_GAP_dom

TSC2 SIPA1L3

3.22e-0411462IPR000331
DomainRAPGAP

TSC2 SIPA1L3

3.22e-0411462PS50085
DomainLaminin_G_1

HSPG2 AGRN

3.22e-0411462PF00054
Domain-

MUC17 AGRN

6.11e-04154623.30.70.960
DomainPWWP

PWWP3A MBD5

1.45e-0323462PF00855
DomainPWWP_dom

PWWP3A MBD5

1.45e-0323462IPR000313
DomainPWWP

PWWP3A MBD5

1.58e-0324462PS50812
Domain-

HSPG2 CELSR1 AGRN

1.65e-03954632.60.120.200
DomainConA-like_dom

HSPG2 CELSR1 AGRN COL27A1

2.04e-03219464IPR013320
DomainEGF_3

HSPG2 CELSR1 MUC17 AGRN

2.63e-03235464PS50026
DomainEGF

HSPG2 CELSR1 MUC17 AGRN

2.63e-03235464SM00181
DomainEGF-like_dom

HSPG2 CELSR1 MUC17 AGRN

3.24e-03249464IPR000742
DomainEGF_CA

HSPG2 CELSR1 AGRN

3.36e-03122463SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 CELSR1 AGRN

3.52e-03124463IPR001881
DomainEGF_1

HSPG2 CELSR1 MUC17 AGRN

3.53e-03255464PS00022
DomainEGF

HSPG2 CELSR1 AGRN

3.68e-03126463PF00008
DomainEGF-like_CS

HSPG2 CELSR1 MUC17 AGRN

3.84e-03261464IPR013032
DomainEGF_2

HSPG2 CELSR1 MUC17 AGRN

4.05e-03265464PS01186
DomainLaminin_G_2

HSPG2 CELSR1

4.36e-0340462PF02210
PathwayBIOCARTA_AGR_PATHWAY

DAG1 AGRN PAK4

5.50e-0531343MM1343
PathwayBIOCARTA_AGR_PATHWAY

DAG1 AGRN PAK4

6.66e-0533343M6220
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

DAG1 HSPG2 MUC17 AGRN

3.72e-04143344M27275
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

DAG1 HSPG2 AGRN

3.80e-0459343M27218
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SRRM1 TSC2 DST CASKIN2 MAPT DENND2B PPFIA1 SIPA1L3 TNS3 PAK4 CAMSAP3

1.97e-08861481136931259
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4F HSPG2 TSC2 CELSR1 DST MBD5 DCTN1 ZNF592 AGRN MED13 SIPA1L3 C2CD2L

2.42e-081105481235748872
Pubmed

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.

DAG1 HSPG2 AGRN

8.60e-08748311802174
Pubmed

Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport.

TMEM108 DST DCTN1

2.06e-07948317287360
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AUTS2 RPRD2 DST ZNF592 CASKIN2 MED13 MDC1 PAK4

6.01e-0752948814621295
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NUSAP1 PPP1R18 CELSR1 DST ZNF592 AGRN MED13 PPFIA1 SIPA1L3 MDC1 CAMSAP3 C2CD2L

6.39e-071497481231527615
Pubmed

Deletion of astroglial connexins weakens the blood-brain barrier.

DAG1 HSPG2 AGRN

8.88e-071448322472609
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

DAG1 HSPG2 AGRN

1.36e-061648317948866
Pubmed

Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells.

CELSR1 CAMSAP3

1.87e-06248233468623
Pubmed

Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.

HSPG2 AGRN

1.87e-06248225506919
Pubmed

Interaction of tau protein with the dynactin complex.

DCTN1 MAPT

1.87e-06248217932487
Pubmed

Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor.

DAG1 AGRN

1.87e-0624828205617
Pubmed

Agrin is involved in lymphocytes activation that is mediated by alpha-dystroglycan.

DAG1 AGRN

1.87e-06248216394267
Pubmed

Agrin is a high-affinity binding protein of dystroglycan in non-muscle tissue.

DAG1 AGRN

1.87e-0624829417121
Pubmed

BPAG1n4 is essential for retrograde axonal transport in sensory neurons.

DST DCTN1

1.87e-06248214581450
Pubmed

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.

DAG1 HSPG2 DST TNS3 PAK4 SLC4A2

2.64e-0628548621423176
Pubmed

Mice with megalencephalic leukoencephalopathy with cysts: a developmental angle.

DAG1 HEPACAM AGRN

3.22e-062148325382142
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

TLK2 SRRM1 TSC2 DCTN1 CASKIN2 PSRC1 DNAH14 PPFIA1 SLC4A2

4.24e-0692548928986522
Pubmed

Renal collecting system growth and function depend upon embryonic γ1 laminin expression.

DAG1 HSPG2 AGRN

4.29e-062348321903675
Pubmed

α-Dystroglycan is essential for the induction of Egr3, a transcription factor important in muscle spindle formation.

DAG1 AGRN

5.59e-06348220213761
Pubmed

Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma.

DAG1 AGRN

5.59e-06348222307776
Pubmed

Disruption of perlecan binding and matrix assembly by post-translational or genetic disruption of dystroglycan function.

DAG1 HSPG2

5.59e-06348216098969
Pubmed

Differential expression profiles between α-dystroglycan and integrin β1 in ameloblastoma: two possible perlecan signalling pathways for cellular growth and differentiation.

DAG1 HSPG2

5.59e-06348221255062
Pubmed

mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.

TSC2 MAPT

5.59e-06348223425014
Pubmed

Reciprocal expressions between α-dystroglycan and integrin β1, perlecan receptors, in the murine enamel organ development.

DAG1 HSPG2

5.59e-06348223722005
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SEMA4F PCARE TSC2 PRR35 DST ZNF592 DNAH14 CAMSAP3

6.92e-0673648829676528
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TLK2 PPP1R18 SRRM1 ZNF592 MAPT MED13 MDC1 CAMSAP3

9.97e-0677448815302935
Pubmed

Conjugation of LG domains of agrins and perlecan to polymerizing laminin-2 promotes acetylcholine receptor clustering.

HSPG2 AGRN

1.12e-05448216219760
Pubmed

Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.

DAG1 HSPG2

1.12e-05448225646087
Pubmed

Dystroglycan is selectively associated with inhibitory GABAergic synapses but is dispensable for their differentiation.

DAG1 AGRN

1.12e-05448212040032
Pubmed

An agrin minigene rescues dystrophic symptoms in a mouse model for congenital muscular dystrophy.

DAG1 AGRN

1.12e-05448211565031
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

DAG1 DST CASKIN2 PPFIA1 PAK4 C2CD2L

1.30e-0537748638117590
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AUTS2 RPRD2 DST SIPA1L3 C2CD2L

1.48e-0522548512168954
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

DAG1 SRRM1 CASKIN2 PSRC1

1.54e-0510848419531213
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

TLK2 PERM1 SEMA4F DST TNS3

1.75e-0523348537704626
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

SRRM1 PCARE DST PPFIA1 MDC1

1.79e-0523448536243803
Pubmed

The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.

HSPG2 AGRN

1.86e-0554827670489
Pubmed

MLC1 is associated with the dystrophin-glycoprotein complex at astrocytic endfeet.

DAG1 AGRN

1.86e-05548217628813
Pubmed

Dystroglycan mediates homeostatic synaptic plasticity at GABAergic synapses.

DAG1 AGRN

1.86e-05548224753587
Pubmed

Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

HSPG2 AGRN

2.79e-05648215668394
Pubmed

Dystroglycan is a scaffold for extracellular axon guidance decisions.

DAG1 CELSR1

2.79e-05648230758284
Pubmed

Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin.

HSPG2 AGRN

3.90e-05748237174615
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TLK2 TSC2 DST DCTN1 AGRN PPFIA1 SIPA1L3 CAMSAP3

4.74e-0596348828671696
Pubmed

Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system.

DAG1 HSPG2

5.19e-05848218586242
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SEMA4F RPRD2 PPFIA1 TNS3 MDC1 SLC4A2 C2CD2L

6.24e-0573348734672954
Pubmed

Retinal ganglion cell axon sorting at the optic chiasm requires dystroglycan.

DAG1 HSPG2

6.67e-05948230149005
Pubmed

Identification and characterization of the interaction between tuberin and 14-3-3zeta.

TSC2 MAPT

6.67e-05948212176984
Pubmed

Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.

TSC2 SSTR3 GJD4

7.99e-056048322889411
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NUSAP1 PPP1R18 CASKIN2 PPFIA1 SIPA1L3 TNS3 PAK4 CAMSAP3

8.62e-05104948827880917
Pubmed

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

HSPG2 AGRN

1.02e-041148217023412
Pubmed

The centrosome protein AKNA regulates neurogenesis via microtubule organization.

DCTN1 CAMSAP3

1.02e-041148230787442
Pubmed

Expression QTL and regulatory network analysis of microtubule-associated protein tau gene.

DST MAPT

1.02e-041148219233709
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

NUSAP1 TLK2 DAG1 CAMTA2 DCTN1 AGRN PPFIA1 PAK4

1.08e-04108448811544199
Pubmed

Protein phosphatase 1α interacting proteins in the human brain.

PPP1R18 RPRD2 DCTN1

1.11e-046748322321011
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

SRRM1 DST MAPT CAMSAP3 C2CD2L

1.16e-0434748517114649
Pubmed

CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.

MAPT CAMSAP3

1.22e-041248232839317
Pubmed

Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development.

DAG1 HSPG2

1.22e-041248221452199
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

HSPG2 AGRN

1.22e-041248216750824
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

DAG1 PPP1R18 DST CASKIN2 SIPA1L3 PAK4

1.23e-0456548625468996
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

DAG1 CASKIN2 PPFIA1 TNS3 PAK4 SLC4A2

1.28e-0456948630639242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CC2D2A SRRM1 DST DCTN1 MED13 PPFIA1 SIPA1L3 ZNF541 CAMSAP3

1.37e-04144248935575683
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SRRM1 ZNF592 SIPA1L3 TNS3 MDC1

1.39e-0436148526167880
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

HSPG2 AGRN

1.44e-041348212682087
Pubmed

Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis.

HSPG2 AGRN

1.68e-041448237408198
Pubmed

Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome.

DAG1 HSPG2

1.68e-041448219783738
Pubmed

Dystroglycan organizes axon guidance cue localization and axonal pathfinding.

DAG1 HSPG2

1.68e-041448223217742
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DST PPFIA1 SIPA1L3 TNS3

2.00e-0420948436779422
Pubmed

No replication of genetic association between candidate polymorphisms and Alzheimer's disease.

HSPG2 MAPT

2.21e-041648219889475
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

TLK2 AUTS2 SRRM1 DST DCTN1 TNS3 PAK4

2.37e-0491048736736316
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

AUTS2 DAG1 SRRM1 DCTN1 MED13 PPFIA1 SIPA1L3

2.57e-0492248727609421
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

DST DCTN1 ZNF592 PPFIA1 CAMSAP3

2.74e-0441848534709266
Pubmed

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma.

SRRM1 CASKIN2 MDC1

3.03e-049448337468549
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

NUSAP1 PPP1R18 SRRM1 DST DCTN1 DENND2B MDC1

3.06e-0494948736574265
Pubmed

Pathway-based approaches to imaging genetics association studies: Wnt signaling, GSK3beta substrates and major depression.

TSC2 MAPT

3.14e-041948220219685
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

DAG1 HSPG2 AGRN

3.32e-049748327559042
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TSC2 DST PPFIA1 SIPA1L3 PAK4

3.69e-0444648524255178
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

DENND2B SIPA1L3 PAK4

3.85e-0410248315778465
Pubmed

DOT1L regulates dystrophin expression and is critical for cardiac function.

DAG1 HSPG2

3.85e-042148221289070
Pubmed

Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones.

HSPG2 AGRN

3.85e-042148226116392
Pubmed

Schwann cell myelination requires integration of laminin activities.

DAG1 HSPG2

3.85e-042148222767514
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

PPP1R18 TSC2 PPFIA1

4.07e-0410448331240132
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

SRRM1 TSC2 PPFIA1 PAK4

4.26e-0425548415324660
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

DAG1 PPFIA1 PAK4 SLC4A2 C2CD2L

4.55e-0446748530194290
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

HEPACAM PPFIA1 C2CD2L

4.80e-0411048327889896
Pubmed

Rheb1 is required for mTORC1 and myelination in postnatal brain development.

TSC2 MAPT

5.48e-042548221238928
Pubmed

Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development.

DAG1 HSPG2

5.48e-042548228760865
Pubmed

Localization of somatostatin receptor genes on mouse chromosomes 2, 11, 12, 15, and 17: correlation with growth QTLs.

TSC2 SSTR3

5.93e-04264829226367
Pubmed

Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS Kinase and Core Components of the Hippo Pathway.

DAG1 DCTN1

5.93e-042648228720576
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

HSPG2 DST DCTN1 ZNF592 MED13

6.03e-0449748523414517
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

SRRM1 RPRD2 DST DCTN1 MDC1

6.54e-0450648530890647
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

AUTS2 CC2D2A

6.89e-042848233953184
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

HSPG2 AGRN

7.39e-042948222613833
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

NUSAP1 HSPG2 RPRD2 C2CD2L

7.64e-0429848430737378
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

DST MBD5 MED13

7.80e-0413048312421765
Pubmed

Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation.

DST PAK4

7.92e-043048224472646
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

AUTS2 RPRD2 MBD5 MAPT DENND2B DNAH14 SIPA1L3 CAMSAP3

9.07e-04148948828611215
Pubmed

Joint influence of small-effect genetic variants on human longevity.

TSC2 SSTR3

1.02e-033448220834067
Pubmed

The spatiotemporal expression pattern of Syndecans in murine embryonic teeth.

HSPG2 AGRN

1.02e-033448232220631
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

DAG1 HSPG2 AGRN

1.09e-0314648327068509
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

SRRM1 DST CASKIN2 PAK4

1.10e-0332948434316702
InteractionYWHAH interactions

CC2D2A SRRM1 TSC2 DST DCTN1 CASKIN2 MAPT DENND2B PPFIA1 SIPA1L3 TNS3 PAK4 CAMSAP3

1.17e-0611024813int:YWHAH
InteractionMAPRE3 interactions

DST DCTN1 MAPT PSRC1 SIPA1L3 CAMSAP3

1.70e-05230486int:MAPRE3
InteractionTRIM36 interactions

DCTN1 MAPT PSRC1 PAK4 CAMSAP3

2.32e-05144485int:TRIM36
InteractionCXADR interactions

DST SSTR3 CASKIN2 MAPT PPFIA1 SIPA1L3 PAK4

2.51e-05369487int:CXADR
InteractionYWHAG interactions

SRRM1 TSC2 DST CASKIN2 MAPT DENND2B PPFIA1 SIPA1L3 TNS3 PAK4 CAMSAP3 C2CD2L

2.62e-0512484812int:YWHAG
InteractionTOP3B interactions

SEMA4F HSPG2 TSC2 CELSR1 DST MBD5 DCTN1 ZNF592 AGRN MED13 SIPA1L3 MDC1 C2CD2L

2.71e-0514704813int:TOP3B
InteractionAQP4 interactions

DAG1 HEPACAM SSTR3

2.81e-0525483int:AQP4
InteractionSFN interactions

TSC2 DST MAPT DENND2B PPFIA1 SIPA1L3 TNS3 PAK4 CAMSAP3

3.18e-05692489int:SFN
InteractionRAB35 interactions

DAG1 DST DCTN1 CASKIN2 PPFIA1 PAK4 SLC4A2 C2CD2L

5.63e-05573488int:RAB35
InteractionRHOQ interactions

DAG1 DST CASKIN2 PPFIA1 TNS3 PAK4 SLC4A2

7.88e-05442487int:RHOQ
InteractionC11orf52 interactions

DST CASKIN2 PPFIA1 SIPA1L3 PAK4 SLC4A2

9.15e-05311486int:C11orf52
InteractionYWHAB interactions

TSC2 DST DCTN1 MAPT DENND2B PPFIA1 SIPA1L3 TNS3 PAK4 CAMSAP3

1.13e-0410144810int:YWHAB
InteractionP4HA3 interactions

SRRM1 TSC2 ZNF592 CASKIN2

1.51e-04113484int:P4HA3
InteractionHEPACAM interactions

HEPACAM MAPT

1.54e-048482int:HEPACAM
InteractionCAMKV interactions

HSPG2 SSTR3 MAPT AGRN

1.78e-04118484int:CAMKV
InteractionPHF24 interactions

PPP1R18 SSTR3

1.98e-049482int:PHF24
InteractionYWHAZ interactions

TLK2 TSC2 DST DCTN1 MAPT DENND2B PPFIA1 SIPA1L3 MDC1 PAK4 CAMSAP3

2.16e-0413194811int:YWHAZ
InteractionPPP1CA interactions

PPP1R18 SRRM1 RPRD2 TSC2 DCTN1 MAPT MDC1 CAMSAP3

2.16e-04696488int:PPP1CA
GeneFamilyBlood group antigens|CD molecules|Proteoglycans

HSPG2 AGRN

5.56e-057302570
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R18 TSC2 MAPT CAMSAP3

2.17e-04181304694
GeneFamilyPWWP domain containing

PWWP3A MBD5

6.02e-04223021147
GeneFamilySterile alpha motif domain containing

CASKIN2 PPFIA1

9.33e-0388302760
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

PPP1R18 DST DENND2B TMEM200B COL27A1

2.14e-061954855562665dd3beb70e2358aa32611a337bef5731c1
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUSAP1 HSPG2 PSRC1 C2CD2L

2.34e-051554848e239470799426ea474a36f57e1b7e0d9365ca5f
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PERM1 CELSR1 FAM241B AGRN

3.21e-05168484ca65321259711321c175ede67bd67a47aad81d7a
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

CC2D2A PWWP3A RPRD2 DENND2B

3.21e-05168484c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PERM1 CELSR1 FAM241B AGRN

3.60e-0517348445808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PERM1 CELSR1 FAM241B AGRN

3.60e-051734847fa9dbcb258c3ab974490063951620e2def03db1
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAG1 HSPG2 FAM241B AGRN

4.02e-05178484a3af5d9c55858e36be0498081029ecb0acaeb3d3
ToppCellPND28-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DAG1 HSPG2 FAM241B AGRN

4.02e-05178484b3b88989bd602cfb55bb5c47731deb99288a8952
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NUSAP1 SEMA4F HSPG2 CASKIN2

4.02e-05178484ea10117026021c959ffc871fc377cdb3e161d264
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HSPG2 CELSR1 AGRN TNS3

4.29e-05181484b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellBasal|World / shred by cell class for mouse tongue

CELSR1 DST AGRN SIPA1L3

4.48e-05183484c6729a207526ff4aa48176207b9353176f631fea
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF213 MED13 COL27A1 SIPA1L3

4.77e-05186484de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ZNF213 MED13 COL27A1 SIPA1L3

4.77e-051864840b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CELSR1 DNAH14 SIPA1L3 TNS3

4.98e-0518848463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

AUTS2 DENND2B DNAH14 COL27A1

4.98e-05188484ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

AUTS2 CELSR1 DENND2B DNAH14

5.40e-05192484efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

DAG1 CELSR1 DENND2B COL27A1

5.97e-051974849d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

DAG1 CELSR1 DENND2B COL27A1

5.97e-0519748461749ccafeb938c310cff1de5ff924a1c794325a
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

AUTS2 TMEM108 DST COL27A1

5.97e-05197484f1c8936986123a3151140c374fcd62d6705c530b
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMEM108 FAM241B MAPT TNS3

6.08e-05198484b58138581f1a9073267d64c1211c5b9b4de71d3e
ToppCellEpithelial_cells-AT1-AT2_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

HSPG2 DST AGRN TNS3

6.08e-05198484fbc46b20bcd44f2083170aacbc6f5dd00fba685c
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Cortical_neuron|GW23 / Sample Type, Dataset, Time_group, and Cell type.

AUTS2 TMEM108 FAM241B MAPT

6.33e-052004847bba2ff09349c8db3d1ccf53520b12cbf7b0abac
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate|5w / Sample Type, Dataset, Time_group, and Cell type.

AUTS2 FAM241B MAPT CAMSAP3

6.33e-05200484c92e4fc0442404481fcac623d691dae6215b852d
ToppCellwk_08-11-Epithelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CELSR1 FAM241B AGRN COL27A1

6.33e-05200484445fc7995ffc440c6256a6aab0bbf33fb0fea028
DrugMuramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A

HSPG2 CASKIN2 AGRN PAK4 SLC4A2 C2CD2L

3.13e-061934863262_UP
DrugCHDM

TSC2 DST

1.30e-053482CID000007735
Drugfelodipine; Down 200; 10uM; MCF7; HT_HG-U133A_EA

DAG1 SEMA4F PWWP3A CAMTA2 SIPA1L3

5.29e-05193485965_DN
Drug0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A

SEMA4F TSC2 CASKIN2 AGRN MYO1F

5.42e-051944854331_DN
DrugClomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; HL60; HT_HG-U133A

CAMTA2 DCTN1 MED13 PPFIA1 PAK4

5.56e-051954851269_DN
DrugPirlindole mesylate [60762-57-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A

AUTS2 DAG1 CASKIN2 MAPT MYO1F

5.83e-051974856519_DN
DrugSulfathiazole [72-14-0]; Down 200; 15.6uM; PC3; HT_HG-U133A

PWWP3A CASKIN2 MAPT AGRN MYO1F

5.83e-051974854183_DN
DrugGallamine triethiodide [65-29-2]; Down 200; 4.4uM; PC3; HT_HG-U133A

SEMA4F CAMTA2 CASKIN2 PPFIA1 SIPA1L3

5.83e-051974852059_DN
DrugNomifensine maleate [32795-47-4]; Down 200; 11.2uM; PC3; HT_HG-U133A

HSPG2 CASKIN2 PPFIA1 SIPA1L3 C2CD2L

5.98e-051984852062_DN
DrugMianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

DAG1 CASKIN2 MAPT C2CD2L MYO1F

5.98e-051984855786_DN
DrugAC1L1B6T

PWWP3A HSPG2 AGRN

7.04e-0538483CID000001308
Diseaseautosomal dominant intellectual developmental disorder (implicated_via_orthology)

AUTS2 MBD5

7.77e-063482DOID:0060307 (implicated_via_orthology)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TLK2 MED13

3.47e-0417482DOID:0060307 (is_implicated_in)
Diseaseosteoarthritis, hip

RPRD2 MAPT COL27A1

4.58e-0492483EFO_1000786
DiseaseCiliopathies

CC2D2A PCARE TSC2

7.72e-04110483C4277690
DiseaseAutosomal Dominant Parkinsonism

DCTN1 MAPT

9.53e-0428482C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

DCTN1 MAPT

9.53e-0428482C0752097
DiseaseParkinsonism, Experimental

DCTN1 MAPT

9.53e-0428482C0752101
DiseaseAutosomal Recessive Parkinsonism

DCTN1 MAPT

9.53e-0428482C0752100
DiseaseFamilial Juvenile Parkinsonism

DCTN1 MAPT

9.53e-0428482C0752104
DiseaseRamsay Hunt Paralysis Syndrome

DCTN1 MAPT

9.53e-0428482C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

DCTN1 MAPT

9.53e-0428482C1868675
Diseaserespiratory failure, COVID-19

DST MAPT

1.02e-0329482EFO_0009686, MONDO_0100096
DiseaseParkinsonism, Juvenile

DCTN1 MAPT

1.09e-0330482C0752105
DiseaseParkinsonian Disorders

DCTN1 MAPT

1.09e-0330482C0242422
DiseasePR interval

DAG1 HSPG2 CASKIN2 PPFIA1 GJD4

1.23e-03495485EFO_0004462

Protein segments in the cluster

PeptideGeneStartEntry
PRVRTTTQPPRGSIP

FAM241B

16

Q96D05
PRRRPGASPTGETPT

SLC4A2

106

P04920
TTRRPKPTRPASTGV

DCTN1

146

Q14203
TTAAPTTRRPPTTAP

AGRN

1301

O00468
TTRRPPTTAPSRVPG

AGRN

1306

O00468
EIRPSPPTSRGGSSR

CAMTA2

306

O94983
PAGRRTTPQTTRPGP

CELSR1

2301

Q9NYQ6
PRGTLSRSQSVSPPP

DENND2B

21

P78524
TRRSPGPGPSQSPRS

CAMSAP3

766

Q9P1Y5
PVPGSTRPIRIEPSS

HSPG2

2146

P98160
PVTPEPTSRATRGRT

MDC1

1546

Q14676
PQTHRPTPRAGSRPS

DST

7531

Q03001
PPTRIRTTTSGVPRG

DAG1

476

Q14118
RRPGPPTSPSIRKQS

GJD4

226

Q96KN9
TLGGRPVSPRRTTPL

AUTS2

1226

Q8WXX7
SSSPPGSGRSTPRRI

PPFIA1

691

Q13136
PLTRSTPPVRGRAGP

PSRC1

191

Q6PGN9
TPVPPRGRLSVASTP

NUSAP1

231

Q9BXS6
TSPSVTPTPARGTPR

CASKIN2

841

Q8WXE0
CRRGSTTPRPHAPTP

PRR35

76

P0CG20
TVRRGPRSLPPIPST

CC2D2A

76

Q9P2K1
SPRNLGTPTSSTPRP

C2CD2L

411

O14523
GSTRSTRPPATMVPP

COL27A1

496

Q8IZC6
PTPIVASSPGRRRGS

DNAH14

106

Q0VDD8
RSPRSTIGSPRPSMP

MBD5

491

Q9P267
SSPPRAPSSPGRSRS

HEPACAM

376

Q14CZ8
PRRSVPPATPATPTS

PPP1R18

476

Q6NYC8
SSTPSSTRSPPPGRD

RPRD2

761

Q5VT52
RPPPSAVTRVGPGSS

PERM1

561

Q5SV97
RTVVPPRPSTVSGSR

PCARE

571

A6NGG8
SSRPPTRARGAPSPG

PAK4

246

O96013
PREGRPPLTSIPVST

MUC17

1921

Q685J3
SVTPRSTARLGPPPS

PWWP3A

336

Q2TAK8
PVSGRVPRSVPRTSL

SEMA4F

31

O95754
PSRRVRSQEPTVGPP

SSTR3

331

P32745
PSPRRGTSPVPSVRS

TMEM200B

191

Q69YZ2
LSLERGPPTPRTTPT

SIPA1L3

1691

O60292
TPRTPRTPRTPRGAG

MED13

1011

Q9UHV7
QPRVPLTPTRGTSSR

TNS3

626

Q68CZ2
PGTSPGRSVPPVARS

TLK2

96

Q86UE8
SPPPVRRGASSSPQR

SRRM1

696

Q8IYB3
SRPGSRVPTEPPATS

ZNF592

936

Q92610
RTPPRASPTGTPSRA

nan

311

Q9UF83
GTPGSRSRTPSLPTP

MAPT

521

P10636
TRTPPRTSQTRTPPR

nan

211

A8MUU9
RTPPGTWLRRTPPRT

nan

446

A8MUU9
ATGPPPTVGARRRPS

ZNF213

151

O14771
PVAPRPSSGSTAPSR

ZFAND4

251

Q86XD8
PSSSPRSPSGLRPRG

TSC2

1446

P49815
TPGVPREASPGSTRR

ZNF541

631

Q9H0D2
SRPTTAPPRTTTRRP

TMEM108

151

Q6UXF1
TTRRPPRPPGSSRKG

TMEM108

161

Q6UXF1
PRGPPSTSLGASRRP

MYO1F

981

O00160