Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhydroxymethylglutaryl-CoA lyase activity

HMGCLL1 HMGCL

4.56e-072142GO:0004419
GeneOntologyMolecularFunctionoxo-acid-lyase activity

HMGCLL1 HMGCL

9.57e-067142GO:0016833
GeneOntologyMolecularFunctioncarbon-carbon lyase activity

HMGCLL1 HMGCL

6.88e-0456142GO:0016830
GeneOntologyBiologicalProcessketone body biosynthetic process

HMGCLL1 HMGCL

7.39e-066152GO:0046951
GeneOntologyBiologicalProcessL-leucine catabolic process

HMGCLL1 HMGCL

1.03e-057152GO:0006552
GeneOntologyBiologicalProcessproteinogenic amino acid catabolic process

HMGCLL1 HMGCL AMT

2.04e-0575153GO:0170040
GeneOntologyBiologicalProcessL-leucine metabolic process

HMGCLL1 HMGCL

2.21e-0510152GO:0006551
GeneOntologyBiologicalProcessL-amino acid catabolic process

HMGCLL1 HMGCL AMT

2.47e-0580153GO:0170035
GeneOntologyBiologicalProcessketone body metabolic process

HMGCLL1 HMGCL

2.70e-0511152GO:1902224
GeneOntologyBiologicalProcesspyruvate family amino acid catabolic process

HMGCLL1 HMGCL

2.70e-0511152GO:0009080
GeneOntologyBiologicalProcesspyruvate family amino acid metabolic process

HMGCLL1 HMGCL

4.47e-0514152GO:0009078
GeneOntologyBiologicalProcessalpha-amino acid catabolic process

HMGCLL1 HMGCL AMT

5.42e-05104153GO:1901606
GeneOntologyBiologicalProcessamino acid catabolic process

HMGCLL1 HMGCL AMT

7.70e-05117153GO:0009063
GeneOntologyBiologicalProcessbranched-chain amino acid catabolic process

HMGCLL1 HMGCL

1.24e-0423152GO:0009083
GeneOntologyBiologicalProcessbranched-chain amino acid metabolic process

HMGCLL1 HMGCL

1.98e-0429152GO:0009081
GeneOntologyBiologicalProcessproteinogenic amino acid metabolic process

HMGCLL1 HMGCL AMT

2.98e-04185153GO:0170039
GeneOntologyBiologicalProcessL-amino acid metabolic process

HMGCLL1 HMGCL AMT

4.21e-04208153GO:0170033
GeneOntologyBiologicalProcessphotoreceptor cell maintenance

USH2A CRB1

5.24e-0447152GO:0045494
GeneOntologyBiologicalProcessvisual perception

CFH USH2A CRB1

5.64e-04230153GO:0007601
GeneOntologyBiologicalProcesssensory perception of light stimulus

CFH USH2A CRB1

5.86e-04233153GO:0050953
GeneOntologyBiologicalProcesseye photoreceptor cell development

CFH CRB1

6.41e-0452152GO:0042462
GeneOntologyBiologicalProcessfatty acid derivative biosynthetic process

HMGCLL1 HMGCL

6.41e-0452152GO:1901570
GeneOntologyBiologicalProcessalpha-amino acid metabolic process

HMGCLL1 HMGCL AMT

7.27e-04251153GO:1901605
GeneOntologyBiologicalProcesscarboxylic acid catabolic process

HMGCLL1 HMGCL AMT

9.18e-04272153GO:0046395
GeneOntologyBiologicalProcessorganic acid catabolic process

HMGCLL1 HMGCL AMT

9.18e-04272153GO:0016054
GeneOntologyBiologicalProcessretina homeostasis

USH2A CRB1

9.70e-0464152GO:0001895
GeneOntologyBiologicalProcesseye photoreceptor cell differentiation

CFH CRB1

1.23e-0372152GO:0001754
GeneOntologyBiologicalProcessphotoreceptor cell development

CFH CRB1

1.26e-0373152GO:0042461
GeneOntologyBiologicalProcessglomerulus development

CFH KLF15

1.40e-0377152GO:0032835
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

HMGCLL1 HMGCL

1.59e-0382152GO:1901568
GeneOntologyBiologicalProcessamino acid metabolic process

HMGCLL1 HMGCL AMT

1.63e-03332153GO:0006520
GeneOntologyBiologicalProcessretina morphogenesis in camera-type eye

CFH CRB1

1.91e-0390152GO:0060042
GeneOntologyBiologicalProcessphotoreceptor cell differentiation

CFH CRB1

2.16e-0396152GO:0046530
GeneOntologyBiologicalProcessneural retina development

CFH CRB1

2.44e-03102152GO:0003407
GeneOntologyBiologicalProcesssmall molecule catabolic process

HMGCLL1 HMGCL AMT

3.20e-03421153GO:0044282
GeneOntologyBiologicalProcessnucleoside bisphosphate metabolic process

HMGCL COASY

4.66e-03142152GO:0033865
GeneOntologyBiologicalProcessribonucleoside bisphosphate metabolic process

HMGCL COASY

4.66e-03142152GO:0033875
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate metabolic process

HMGCL COASY

4.66e-03142152GO:0034032
GeneOntologyBiologicalProcesspurine ribonucleotide metabolic process

CFH HMGCL COASY

5.54e-03512153GO:0009150
GeneOntologyBiologicalProcesspeptidyl-lysine modification

KLF15 CSKMT

6.02e-03162152GO:0018205
GeneOntologyBiologicalProcessribonucleotide metabolic process

CFH HMGCL COASY

6.19e-03533153GO:0009259
GeneOntologyBiologicalProcesssensory perception

CFH USH2A CRB1 HOXD1

6.25e-031072154GO:0007600
GeneOntologyBiologicalProcessribose phosphate metabolic process

CFH HMGCL COASY

6.42e-03540153GO:0019693
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

CFH CRB1

6.68e-03171152GO:0048593
GeneOntologyBiologicalProcessnephron development

CFH KLF15

6.91e-03174152GO:0072006
GeneOntologyCellularComponentphotoreceptor inner segment

USH2A CRB1

1.40e-0378152GO:0001917
GeneOntologyCellularComponentbasement membrane

USH2A LAMB4

3.38e-03122152GO:0005604
GeneOntologyCellularComponentphotoreceptor cell cilium

USH2A CRB1

4.36e-03139152GO:0097733
GeneOntologyCellularComponentapical plasma membrane

SLC13A2 USH2A CRB1

4.64e-03487153GO:0016324
GeneOntologyCellularComponent9+0 non-motile cilium

USH2A CRB1

5.25e-03153152GO:0097731
GeneOntologyCellularComponentmitochondrial matrix

HMGCL AMT COASY

5.66e-03523153GO:0005759
GeneOntologyCellularComponentapical part of cell

SLC13A2 USH2A CRB1

7.97e-03592153GO:0045177
GeneOntologyCellularComponentnon-motile cilium

USH2A CRB1

8.48e-03196152GO:0097730
MousePhenoketoaciduria

SLC13A2 KLF15

3.03e-0510122MP:0002893
MousePhenoabnormal photoreceptor outer segment morphology

CFH USH2A CRB1

2.07e-04141123MP:0003729
MousePhenoshort photoreceptor inner segment

USH2A CRB1

2.17e-0426122MP:0008582
DomainHMG_COA_LYASE

HMGCLL1 HMGCL

6.02e-072152PS01062
DomainPYR_CT

HMGCLL1 HMGCL

1.81e-063152IPR000891
DomainHMGL-like

HMGCLL1 HMGCL

1.81e-063152PF00682
DomainPYR_CT

HMGCLL1 HMGCL

1.81e-063152PS50991
DomainLAMININ_NTER

USH2A LAMB4

7.18e-0516152PS51117
DomainLaminin_N

USH2A LAMB4

7.18e-0516152PF00055
DomainLaminin_N

USH2A LAMB4

7.18e-0516152IPR008211
DomainLamNT

USH2A LAMB4

7.18e-0516152SM00136
DomainEGF_LAM_1

USH2A LAMB4

2.59e-0430152PS01248
DomainEGF_LAM_2

USH2A LAMB4

2.59e-0430152PS50027
DomainEGF_Lam

USH2A LAMB4

3.53e-0435152SM00180
DomainLaminin_EGF

USH2A LAMB4

3.53e-0435152PF00053
DomainLAM_G_DOMAIN

USH2A CRB1

4.16e-0438152PS50025
DomainLaminin_EGF

USH2A LAMB4

4.16e-0438152IPR002049
DomainLaminin_G_2

USH2A CRB1

4.61e-0440152PF02210
Domain-

HMGCLL1 HMGCL

5.09e-04421523.20.20.70
DomainLamG

USH2A CRB1

5.59e-0444152SM00282
DomainAldolase_TIM

HMGCLL1 HMGCL

5.59e-0444152IPR013785
DomainLaminin_G

USH2A CRB1

9.70e-0458152IPR001791
DomainEGF_1

USH2A LAMB4 CRB1

1.01e-03255153PS00022
Domain-

USH2A CRB1

2.57e-03951522.60.120.200
DomainConA-like_dom

USH2A CRB1

1.30e-02219152IPR013320
DomainEGF-like_CS

LAMB4 CRB1

1.81e-02261152IPR013032
DomainEGF_2

LAMB4 CRB1

1.86e-02265152PS01186
PathwayKEGG_MEDICUS_REFERENCE_LEUCINE_DEGRADATION

HMGCLL1 HMGCL

1.64e-057132M47633
PathwayREACTOME_SYNTHESIS_OF_KETONE_BODIES

HMGCLL1 HMGCL

2.19e-058132M27718
PathwayREACTOME_SYNTHESIS_OF_KETONE_BODIES

HMGCLL1 HMGCL

2.19e-058132MM15460
PathwayREACTOME_KETONE_BODY_METABOLISM

HMGCLL1 HMGCL

3.52e-0510132MM15437
PathwayREACTOME_KETONE_BODY_METABOLISM

HMGCLL1 HMGCL

3.52e-0510132M27706
PathwayWP_COMPLEMENT_SYSTEM_IN_NEURONAL_DEVELOPMENT_AND_PLASTICITY

CFH CRB1

4.14e-03106132M42535
Pubmed

Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol.

HMGCLL1 HMGCL

1.74e-07215222847177
Pubmed

3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL). Cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency.

HMGCLL1 HMGCL

1.74e-0721528440722
Pubmed

Application of a high-throughput genotyping method for loci exclusion in non-consanguineous Australian pedigrees with autosomal recessive retinitis pigmentosa.

USH2A CRB1

1.74e-07215222876132
Pubmed

Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase.

HMGCLL1 HMGCL

5.21e-07315222865860
Pubmed

Utility of molecular testing for related retinal dystrophies.

USH2A CRB1

1.04e-06415216767206
Pubmed

Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip.

CFH USH2A CRB1

6.73e-068715320801516
Pubmed

Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa.

USH2A CRB1

2.65e-051815220591486
CytobandEnsembl 112 genes in cytogenetic band chr1q31

CFH CRB1

2.73e-0475152chr1q31
CytobandEnsembl 112 genes in cytogenetic band chr3p21

AMT ACTR8

4.67e-03316152chr3p21
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Rgs4_(Striatum,_interneuron)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

USH2A HOXD1

2.54e-0471152149504ce72da0730074ea436fc2034ce8cb585d5
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Igfbp4-Inhibitory_Neuron.Gad1Gad2.Igfbp4.Rgs4_(Striatum,_interneuron)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

USH2A HOXD1

2.54e-0471152b0dbb059a7d05f825da608879b23aeebd6e9e61f
ToppCellSubstantia_nigra-Macroglia-OLIGODENDROCYTE-O2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

USH2A HOXD1

5.14e-04101152a5a3a79f7a61dd4528615c3abaced1c176fd137a
ToppCellControl-Epithelial_alveolar-AT_1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC13A2 LAMB4

5.66e-04106152d8868c10785e52a1c22c91e1d0e208f2070393bb
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-10|TCGA-Brain / Sample_Type by Project: Shred V9

SLC13A2 USH2A

6.09e-04110152518b21e5af2db1c8bfe7acf3cfff502897053ca8
ToppCellLPS-IL1RA-Endothelial-Mes-Like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

USH2A CRB1

6.89e-041171525a23770806b4612bed4ae6fd716abdec7f7f56c6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFH CCIN

8.36e-04129152a60935ff9c5a841899ccfe90531533ba4c546df3
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC13A2 KRT81

8.75e-04132152c6bf0b4b9e33b517629faf4559a21d7ba720ee6a
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CFH KRT81

1.01e-03142152f4e4cde228149d5a536fbf0517ed71d81e296faf
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USH2A CRB1

1.05e-0314515296712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CFH KRT81

1.13e-03150152ecc4fc94958cf2378dd003966dccba81b3c00f8e
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AMT ACTR8

1.17e-0315315288ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

AMT ACTR8

1.17e-03153152553dff9688a1996d8f4ba16e60c683593d781389
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH KRT81

1.19e-031541528dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|343B / Donor, Lineage, Cell class and subclass (all cells)

KRT81 AMT

1.23e-031571520362c04b7b0b5017964b3a73ee678ae53e7238d7
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

KRT81 CCIN

1.26e-0315915285501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HOXD1

1.26e-031591529f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HOXD1

1.26e-03159152c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

KRT81 CCIN

1.26e-0315915257df5c9b678a15eb5e025e1a80de2e6769cc13d5
ToppCellControl-APC-like-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

ACTR8 COASY

1.28e-03160152463dd624ca5c375b6ff7c269f4ef4b9d74f4b669
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USH2A CRB1

1.28e-03160152c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USH2A CRB1

1.28e-0316015225c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-2|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

SLC13A2 HMGCLL1

1.33e-031631522dfd11f5803822ba01b92adf4395a3b3adda68f5
ToppCellfacs-Marrow-KLS-24m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AMT COASY

1.34e-03164152d2b5f51af7fcffddebe997ee302bacbd85d76852
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC13A2 HMGCL

1.34e-031641522a00515d91ea03efcfc2a3d3c805dc2711867fcd
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like-ILC3|blood / Manually curated celltypes from each tissue

CFH KRT81

1.36e-03165152f012a27ece54c0f7b73a2f4f89c6ee8b865f8782
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CFH KLF15

1.38e-0316615294636dbc039f794c735960c3425e00bdd5523602
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH CCIN

1.39e-03167152a4a795751644b22af616335379e64ae95175180c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.41e-03168152d19a115365c5415e51c039718d7669de788fcf33
ToppCelldroplet-Heart-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.43e-031691522e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH LAMB4

1.43e-03169152c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.43e-03169152a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LAMB4

1.44e-031701522d880223d01bde4bf777bd6f50b7d2768489075f
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LAMB4

1.44e-031701520cc20322cb3e3e7bbd4daad8785c99f80e355c16
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.46e-031711522a34685f7d83d1cf9a88d304173cbca868c5f9fd
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue-Stomach_normal_tissue|TCGA-Stomach / Sample_Type by Project: Shred V9

KLF15 HMGCLL1

1.46e-031711520bf36930bd7fc63691f48a15db93deb1dd937c10
ToppCellTCGA-Stomach-Solid_Tissue_Normal-Stomach_normal_tissue|TCGA-Stomach / Sample_Type by Project: Shred V9

KLF15 HMGCLL1

1.46e-031711520f8d038858a4618b4348becc26a618d43b10d9d6
ToppCellTCGA-Stomach-Solid_Tissue_Normal|TCGA-Stomach / Sample_Type by Project: Shred V9

KLF15 HMGCLL1

1.46e-03171152791d37fe94ff2820fb409bbd38b31799df700ba1
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH KLF15

1.49e-031731528565966f4faf5f31190f65123a1bd221782db814
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC13A2 HOXD1

1.51e-03174152ca067e8ec55bbc3deafc09f08bc13af08364d165
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH CRB1

1.51e-0317415242dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH CRB1

1.51e-03174152f04edf2ca6788875c9918611e416fb739924382e
ToppCelldroplet-Heart-nan-18m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.51e-03174152cf4e0567f2a4ebe5534046b1c091af59b55bdc4f
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFH HMGCLL1

1.55e-031761521af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.56e-031771529ec7f1e64312d26d434b3312b58386715dbad644
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.56e-03177152016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellwk_15-18-Epithelial-PNS-COL20A1+_Schwann|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CRB1 HOXD1

1.56e-03177152b8cc6a7abf83a9844a5293b6cc4b19135b51fd53
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH LAMB4

1.56e-031771529e65b39fd797b6ce204b6480415810d1923acee5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.58e-0317815278a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

KLF15 LAMB4

1.62e-03180152806e2f6138b630b9d7c41df75ec208e0a2298ee0
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH KLF15

1.63e-03181152091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-ILCP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

LAMB4 KRT81

1.65e-031821526bd48c5d60a259719f65cacee4b8135247e78fa9
ToppCellP28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH KLF15

1.65e-0318215219c5e3a9d9b3728303b682102e276adfe93aa759
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFH HMGCLL1

1.65e-031821520e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CFH HMGCLL1

1.65e-0318215200a148b1e499bf16325491536d187d4dd6b70c06
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CRB1 HOXD1

1.65e-03182152b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellP28-Mesenchymal|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH KLF15

1.65e-0318215269f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC13A2 USH2A

1.67e-03183152d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFH LAMB4

1.67e-0318315290c66ffd2c1f87c91f9a9886e28aeec542f9df85
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CRB1 HOXD1

1.67e-03183152f517215ff45dec914af52dfdbc4579c19654c3aa
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.69e-03184152c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCelldroplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.69e-0318415289ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH KLF15

1.69e-03184152924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.69e-031841524df6027fa635996c1eddb920f88a5265772df1cd
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFH KLF15

1.70e-03185152e34473eea3a58c041183a4f52137366cd9489495
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH HMGCLL1

1.70e-031851528ed10ba581849c9c4ac4397226be2b62b4b3b900
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CFH HMGCLL1

1.70e-031851527dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CRB1 HOXD1

1.70e-03185152a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.70e-03185152ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFH HMGCLL1

1.70e-03185152b8052cebb73f41abe6faf0aa847be7c8ef23ae94
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.70e-03185152eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH KLF15

1.70e-03185152f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCell(5)_Glands_duct|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

SLC13A2 KRT81

1.72e-03186152ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCell(5)_Epithelial_cells-(5)_Glands_duct|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

SLC13A2 KRT81

1.72e-03186152219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

USH2A LAMB4

1.72e-0318615223b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CFH KRT81

1.74e-03187152f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CFH HMGCLL1

1.74e-031871525258674d0346e5c51a4b965efcdc1790c970845d
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

CFH HMGCLL1

1.74e-03187152bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellPCW_05-06-Neuronal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CRB1 HOXD1

1.74e-0318715203a2ed85b171c887d4f3b0f4fe2e1cb4a853e658
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

CFH HMGCLL1

1.76e-031881527b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CFH KRT81

1.76e-03188152de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

CFH KRT81

1.76e-03188152f4734d5b703678670ece204a0519cf015e180a6e
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFH HMGCLL1

1.78e-031891524f9608b84d135268a17455661870c46ae8554a24
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH CCIN

1.78e-03189152dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.80e-03190152efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF15 CRB1

1.80e-031901527179f980f895d3e5b839b5ae26b5c991787bfe3a
ToppCellBL-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC13A2 CFH

1.80e-03190152f2abe4bc28e934287e2dcd7b9399d5af78c5c8cf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.82e-0319115239092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-031911528a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-03191152de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-0319115236467322096bc766cd777dae3bfb4e65511e492c
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-0319115294795daf05061baa3b72a1b01c9e940af86de044
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-03191152b5210de890d338602857b5907135705a507bc2b0
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-03191152d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-03191152ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFH HMGCLL1

1.82e-031911526688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCelldroplet-Lung-21m-Mesenchymal|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-0319115210a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH KLF15

1.82e-03191152d4f535b06ad483448ab692e9900c872c78cbed60
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CFH HMGCLL1

1.82e-03191152ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFH KLF15

1.83e-03192152dcf2d0c2e8868104c4dba410456207f0d947029a
ComputationalGenes in the cancer module 287.

USH2A CRB1

9.32e-0450102MODULE_287
ComputationalNeighborhood of THRA

SLC13A2 CCIN

1.09e-0354102MORF_THRA
ComputationalLiver genes - metabolism and xenobiotics.

SLC13A2 CFH HMGCL AMT

1.21e-03563104MODULE_23
ComputationalNeighborhood of PAX7

SLC13A2 CFH CCIN

1.58e-03266103MORF_PAX7
Drugcitronellic acid

HMGCLL1 HMGCL

6.07e-066152CID000010402
DrugAC1ODY4W

HMGCLL1 HMGCL

2.66e-0512152CID000009989
Diseasehemopexin measurement

CFH CRB1

8.32e-0611122EFO_0008149
Diseasecomplement factor H-related protein 3 measurement

CFH USH2A CRB1

3.91e-05169123EFO_0600056
Diseaseretinitis pigmentosa (implicated_via_orthology)

USH2A CRB1

5.29e-0527122DOID:10584 (implicated_via_orthology)
Diseasecomplement factor H-related protein 2 measurement

CFH CRB1

6.12e-0529122EFO_0600055
Diseasecomplement factor H measurement

CFH CRB1

1.23e-0441122EFO_0008097
Diseaseretinitis pigmentosa (is_implicated_in)

USH2A CRB1

1.23e-0441122DOID:10584 (is_implicated_in)
Diseasecomplement factor H-related protein 5 measurement

CFH CRB1

1.29e-0442122EFO_0008098
Diseasecomplement factor H-related protein 4 measurement

CFH CRB1

1.76e-0449122EFO_0600091
Diseasecomplement factor H-related protein 1 measurement

CFH CRB1

2.31e-0456122EFO_0600054
DiseaseRetinitis pigmentosa

USH2A CRB1

4.03e-0474122cv:C0035334

Protein segments in the cluster

PeptideGeneStartEntry
VTCGGTVYSVGGSIA

CCIN

371

Q13939
TYGSGLSSTCIVDVG

ACTR8

271

Q9H981
YVTADGETSGSITCG

CFH

481

P08603
EYVSCSSSGGVGGDV

HOXD1

6

Q9GZZ0
DVGCGTSSLCTGLYT

CSKMT

81

A8MUP2
CSCYGGGLGTESQDS

KLF15

61

Q9UIH9
TTYLASGGLSGGVCE

LAMB4

346

A4D0S4
SGCRVTRCGYTGEDG

AMT

216

P48728
GYSGTICETTIGSCG

CRB1

101

P82279
CYSASIGGIATLTGT

SLC13A2

226

Q13183
GCYEISLGDTIGVGT

HMGCLL1

241

Q8TB92
CSGGNGYLGGCTESL

USH2A

2796

O75445
GCYEISLGDTIGVGT

HMGCL

196

P35914
TCLYVIGLTGISGSG

COASY

356

Q13057
GSCGVGSCGISSLGV

KRT81

481

Q14533