Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiongrowth hormone receptor binding

GH1 GH2 JAK1 CSH1 CSH2

1.62e-1010755GO:0005131
GeneOntologyMolecularFunctionprolactin receptor binding

GH1 GH2 CSH1 CSH2

6.37e-097754GO:0005148
GeneOntologyMolecularFunctionhormone receptor binding

GH1 GH2 JAK1 CSH1 CSH2

1.67e-0734755GO:0051427
GeneOntologyMolecularFunction5-diphosphoinositol pentakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

1.39e-052752GO:0033857
GeneOntologyMolecularFunctioninositol hexakisphosphate 3-kinase activity

PPIP5K1 PPIP5K2

8.31e-054752GO:0052724
GeneOntologyMolecularFunctioninositol hexakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

8.31e-054752GO:0052723
GeneOntologyMolecularFunctioninositol hexakisphosphate 5-kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000832
GeneOntologyMolecularFunctiondiphosphoinositol pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000829
GeneOntologyMolecularFunctioninositol hexakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000828
GeneOntologyMolecularFunctioninositol-1,3,4,5,6-pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

1.38e-045752GO:0000827
GeneOntologyMolecularFunctioninositol phosphate kinase activity

PPIP5K1 PPIP5K2

7.49e-0411752GO:0180030
GeneOntologyMolecularFunctioncytokine receptor binding

GH1 GH2 JAK1 FEM1B CSH1 CSH2

1.37e-03324756GO:0005126
GeneOntologyMolecularFunctionhormone activity

GH1 GH2 CSH1 CSH2

1.68e-03135754GO:0005179
GeneOntologyMolecularFunctionkinase activity

JAK1 ANKK1 SMG1 TRPM7 PDK2 NEK7 PPIP5K1 PRKG2 PPIP5K2

2.20e-03764759GO:0016301
GeneOntologyBiologicalProcessgrowth hormone receptor signaling pathway

GH1 GH2 JAK1 CSH1 CSH2

3.00e-0826735GO:0060396
GeneOntologyBiologicalProcesscellular response to growth hormone stimulus

GH1 GH2 JAK1 CSH1 CSH2

3.67e-0827735GO:0071378
GeneOntologyBiologicalProcesspositive regulation of steroid hormone biosynthetic process

GH1 GH2 CSH1 CSH2

1.01e-0713734GO:0090031
GeneOntologyBiologicalProcessresponse to growth hormone

GH1 GH2 JAK1 CSH1 CSH2

3.28e-0741735GO:0060416
GeneOntologyBiologicalProcesspositive regulation of hormone biosynthetic process

GH1 GH2 CSH1 CSH2

5.38e-0719734GO:0046886
GeneOntologyBiologicalProcessregulation of steroid hormone biosynthetic process

GH1 GH2 CSH1 CSH2

1.45e-0624734GO:0090030
GeneOntologyBiologicalProcesspositive regulation of hormone metabolic process

GH1 GH2 CSH1 CSH2

2.03e-0626734GO:0032352
GeneOntologyBiologicalProcesspositive regulation of receptor signaling pathway via STAT

GH1 GH2 JAK1 CSH1 CSH2

3.38e-0665735GO:1904894
GeneOntologyBiologicalProcessregulation of hormone biosynthetic process

GH1 GH2 CSH1 CSH2

7.81e-0636734GO:0046885
GeneOntologyBiologicalProcesspositive regulation of steroid biosynthetic process

GH1 GH2 CSH1 CSH2

9.73e-0638734GO:0010893
GeneOntologyBiologicalProcesspositive regulation of steroid metabolic process

GH1 GH2 CSH1 CSH2

1.46e-0542734GO:0045940
GeneOntologyBiologicalProcesstyrosine phosphorylation of STAT protein

GH1 GH2 JAK1 CSH1 CSH2

1.68e-0590735GO:0007260
GeneOntologyBiologicalProcessregulation of response to nutrient levels

GH1 GH2 CSH1 CSH2

2.11e-0546734GO:0032107
GeneOntologyBiologicalProcesspositive regulation of multicellular organism growth

GH1 GH2 CSH1 CSH2

2.30e-0547734GO:0040018
GeneOntologyBiologicalProcessresponse to food

GH1 GH2 CSH1 CSH2

5.30e-0558734GO:0032094
GeneOntologyBiologicalProcesspositive regulation of receptor signaling pathway via JAK-STAT

GH1 GH2 CSH1 CSH2

5.30e-0558734GO:0046427
GeneOntologyBiologicalProcessregulation of hormone metabolic process

GH1 GH2 CSH1 CSH2

5.30e-0558734GO:0032350
GeneOntologyBiologicalProcesspositive regulation of D-glucose transmembrane transport

GH1 GH2 CSH1 CSH2

7.34e-0563734GO:0010828
GeneOntologyBiologicalProcesspositive regulation of tyrosine phosphorylation of STAT protein

GH1 GH2 CSH1 CSH2

1.05e-0469734GO:0042531
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

GH1 GH2 CSH1 CSH2 UBE3A

1.21e-04136735GO:0030518
GeneOntologyBiologicalProcesslung alveolus development

GH1 GH2 CSH1 CSH2

1.45e-0475734GO:0048286
GeneOntologyBiologicalProcessregulation of receptor signaling pathway via STAT

GH1 GH2 JAK1 CSH1 CSH2

1.54e-04143735GO:1904892
GeneOntologyBiologicalProcesshormone biosynthetic process

GH1 GH2 CSH1 CSH2

2.15e-0483734GO:0042446
GeneOntologyBiologicalProcesssteroid hormone receptor signaling pathway

GH1 GH2 CSH1 CSH2 UBE3A

2.24e-04155735GO:0043401
GeneOntologyBiologicalProcessregulation of tyrosine phosphorylation of STAT protein

GH1 GH2 CSH1 CSH2

2.35e-0485734GO:0042509
GeneOntologyBiologicalProcessregulation of intracellular steroid hormone receptor signaling pathway

GH1 GH2 CSH1 CSH2

2.57e-0487734GO:0033143
GeneOntologyBiologicalProcessregulation of neuron projection development

UBE3A WASHC5 RRN3 CFL1 PPFIA2 SCN1B ANAPC2 ID1 SYNGAP1

3.01e-04612739GO:0010975
GeneOntologyBiologicalProcessregulation of multicellular organism growth

GH1 GH2 CSH1 CSH2

3.32e-0493734GO:0040014
GeneOntologyBiologicalProcesscellular response to peptide hormone stimulus

GH1 GH2 JAK1 CSH1 CSH2 PDK2 CFL1

3.97e-04381737GO:0071375
GeneOntologyBiologicalProcessresponse to light stimulus

GH1 GH2 CSH1 CSH2 ID2 MSH2 SYNGAP1

4.03e-04382737GO:0009416
GeneOntologyBiologicalProcesspositive regulation of transmembrane transport

GH1 GH2 CSH1 CSH2 SCN1B TRPC1

4.12e-04273736GO:0034764
GeneOntologyBiologicalProcessregulation of neurogenesis

GH1 GH2 CSH1 CSH2 ANAPC2 ID1 ID2 SYNGAP1

4.63e-04515738GO:0050767
GeneOntologyBiologicalProcessneuroblast proliferation

GH1 GH2 CSH1 CSH2

5.08e-04104734GO:0007405
GeneOntologyBiologicalProcessregulation of D-glucose transmembrane transport

GH1 GH2 CSH1 CSH2

5.27e-04105734GO:0010827
GeneOntologyBiologicalProcessinositol metabolic process

PPIP5K1 PPIP5K2

5.46e-0410732GO:0006020
GeneOntologyBiologicalProcessregulation of steroid biosynthetic process

GH1 GH2 CSH1 CSH2

5.46e-04106734GO:0050810
GeneOntologyBiologicalProcessnegative regulation of DNA binding

RSF1 ID1 ID2

6.17e-0447733GO:0043392
GeneOntologyBiologicalProcessregulation of lipid metabolic process

GH1 GH2 CSH1 CSH2 PDK2 ID2 LACTB

6.60e-04415737GO:0019216
GeneOntologyBiologicalProcessdendrite morphogenesis

UBE3A CFL1 PPFIA2 ANAPC2 ID1

6.86e-04198735GO:0048813
GeneOntologyBiologicalProcesscell surface receptor signaling pathway via JAK-STAT

GH1 GH2 JAK1 CSH1 CSH2

6.86e-04198735GO:0007259
GeneOntologyBiologicalProcessnuclear receptor-mediated signaling pathway

GH1 GH2 CSH1 CSH2 UBE3A

7.51e-04202735GO:0141193
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

UBE3A WASHC5 RRN3 CFL1 PPFIA2 SCN1B ANAPC2 ID1 PLCE1 SYNGAP1

7.64e-048467310GO:0120035
GeneOntologyBiologicalProcessregulation of cell projection organization

UBE3A WASHC5 RRN3 CFL1 PPFIA2 SCN1B ANAPC2 ID1 PLCE1 SYNGAP1

8.90e-048637310GO:0031344
GeneOntologyBiologicalProcesspositive regulation of lipid biosynthetic process

GH1 GH2 CSH1 CSH2

8.98e-04121734GO:0046889
GeneOntologyBiologicalProcessdevelopmental maturation

GH1 FEM1B ATP6V1B1 WASHC5 ANAPC2 ID2 TDRD6

9.17e-04439737GO:0021700
GeneOntologyBiologicalProcessregulation of receptor signaling pathway via JAK-STAT

GH1 GH2 CSH1 CSH2

1.01e-03125734GO:0046425
GeneOntologyBiologicalProcesscell surface receptor signaling pathway via STAT

GH1 GH2 JAK1 CSH1 CSH2

1.01e-03216735GO:0097696
GeneOntologyBiologicalProcesspositive regulation of synaptic plasticity

CFL1 ANAPC2

1.09e-0314732GO:0031915
GeneOntologyBiologicalProcessspindle organization

SUGT1 ATRX WASHC5 NEK7 DYNC1H1

1.19e-03224735GO:0007051
GeneOntologyBiologicalProcessdendrite development

UBE3A CFL1 PPFIA2 ANAPC2 ID1 SYNGAP1

1.20e-03335736GO:0016358
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

SEMA3D UBE3A CFL1 PPFIA2 SCN1B ANAPC2 ID1 ID2 SYNGAP1

1.26e-03748739GO:0048667
GeneOntologyBiologicalProcesspositive regulation of growth

GH1 GH2 CSH1 CSH2 CFL1 ANAPC2

1.27e-03339736GO:0045927
GeneOntologyBiologicalProcesscellular response to nitrogen compound

GH1 GH2 JAK1 CSH1 ATRX CSH2 PDK2 CFL1 TRPC1

1.31e-03752739GO:1901699
GeneOntologyBiologicalProcessregulation of steroid metabolic process

GH1 GH2 CSH1 CSH2

1.35e-03135734GO:0019218
GeneOntologyBiologicalProcessneural precursor cell proliferation

GH1 GH2 CSH1 CSH2 ID2

1.42e-03233735GO:0061351
GeneOntologyBiologicalProcessregulation of cell cycle

ANKK1 FEM1B GTPBP4 ATRX TTC28 ANAPC2 NEK7 ID2 MSH2 CCNJ COPS5 DYNC1H1

1.43e-0312567312GO:0051726
GeneOntologyCellularComponentgrowth hormone receptor complex

GH1 GH2 CSH1 CSH2

2.04e-096734GO:0070195
MousePhenodecreased pituitary gland weight

GH1 GH2 CSH1 CSH2

2.59e-088634MP:0008938
MousePhenoabsent somatotrophs

GH1 GH2 CSH1 CSH2

4.64e-089634MP:0008330
MousePhenoabsent lactotrophs

GH1 GH2 CSH1 CSH2

4.64e-089634MP:0008333
MousePhenoincreased circulating ghrelin level

GH1 GH2 CSH1 CSH2

1.80e-0712634MP:0011612
MousePhenoabnormal pituitary gland weight

GH1 GH2 CSH1 CSH2

1.80e-0712634MP:0008937
MousePhenoabnormal circulating ghrelin level

GH1 GH2 CSH1 CSH2

4.93e-0715634MP:0011611
MousePhenodecreased lactotroph cell number

GH1 GH2 CSH1 CSH2

8.53e-0717634MP:0008332
MousePhenoabnormal lactotroph morphology

GH1 GH2 CSH1 CSH2

1.38e-0619634MP:0008323
MousePhenodecreased somatotroph cell number

GH1 GH2 CSH1 CSH2

2.12e-0621634MP:0008329
MousePhenosmall adenohypophysis

GH1 GH2 CSH1 CSH2

3.11e-0623634MP:0008321
MousePhenoabnormal somatotroph morphology

GH1 GH2 CSH1 CSH2

3.72e-0624634MP:0008322
MousePhenodisproportionate dwarf

GH1 GH2 CSH1 CSH2 PRKG2

5.53e-0657635MP:0002427
MousePhenodelayed vaginal opening

GH1 GH2 CSH1 CSH2

7.07e-0628634MP:0002636
MousePhenosmall pituitary gland

GH1 GH2 CSH1 CSH2

9.40e-0630634MP:0005361
MousePhenoabnormal timing of vaginal opening

GH1 GH2 CSH1 CSH2

1.08e-0531634MP:0020150
MousePhenoabnormal pituitary gland size

GH1 GH2 CSH1 CSH2

3.69e-0542634MP:0008936
MousePhenoincreased brown adipose tissue amount

GH1 GH2 CSH1 CSH2

4.05e-0543634MP:0000005
MousePhenodelayed sexual maturation

GH1 GH2 CSH1 CSH2

6.82e-0549634MP:0001938
MousePhenoincreased white adipose tissue amount

GH1 GH2 CSH1 CSH2

8.62e-0552634MP:0000008
MousePhenoabnormal bone mineral density

GH1 GH2 JAK1 CSH1 TTC28 CSH2 UBE3A RSF1 ID1 TNFAIP1 FAR1

1.40e-046526311MP:0010119
MousePhenodecreased kidney weight

GH1 GH2 CSH1 CSH2

2.19e-0466634MP:0003918
MousePhenodecreased bone mineral density

GH1 GH2 JAK1 CSH1 TTC28 CSH2 UBE3A ID1 TNFAIP1

2.63e-04476639MP:0000063
MousePhenoabnormal sexual maturation

GH1 GH2 CSH1 CSH2

3.40e-0474634MP:0001937
MousePhenoabnormal pituitary gland morphology

GH1 GH2 CSH1 CSH2 AIP

3.50e-04135635MP:0000633
MousePhenoabnormal white adipose tissue amount

GH1 GH2 CSH1 CSH2 ID2

3.87e-04138635MP:0001781
MousePhenoabnormal brown adipose tissue amount

GH1 GH2 CSH1 CSH2

5.04e-0482634MP:0001778
MousePhenoabnormal neuroendocrine gland morphology

GH1 GH2 CSH1 CSH2 AIP

6.77e-04156635MP:0000631
MousePhenoabnormal secondary sex determination

GH1 GH2 CSH1 CSH2

7.16e-0490634MP:0002212
MousePhenoabnormal adenohypophysis morphology

GH1 GH2 CSH1 CSH2

7.78e-0492634MP:0004163
DomainSOMATOTROPIN_2

GH1 GH2 CSH1 CSH2

3.20e-096734PS00338
DomainHormone_1

GH1 GH2 CSH1 CSH2

3.20e-096734PF00103
DomainSOMATOTROPIN_1

GH1 GH2 CSH1 CSH2

3.20e-096734PS00266
DomainSomatotropin

GH1 GH2 CSH1 CSH2

7.45e-097734IPR001400
DomainSomatotropin_CS

GH1 GH2 CSH1

5.70e-075733IPR018116
Domain4_helix_cytokine_core

GH1 GH2 CSH1 CSH2

4.67e-0551734IPR012351
Domain-

ANKK1 FEM1B IBTK TRPC1 TRPV3 ANKRD18A ASB15

5.17e-052487371.25.40.20
DomainANK

ANKK1 FEM1B IBTK TRPC1 TRPV3 ANKRD18A ASB15

5.58e-05251737SM00248
DomainANK_REPEAT

ANKK1 FEM1B IBTK TRPC1 TRPV3 ANKRD18A ASB15

5.86e-05253737PS50088
DomainAnkyrin_rpt-contain_dom

ANKK1 FEM1B IBTK TRPC1 TRPV3 ANKRD18A ASB15

6.01e-05254737IPR020683
DomainANK_REP_REGION

ANKK1 FEM1B IBTK TRPC1 TRPV3 ANKRD18A ASB15

6.01e-05254737PS50297
DomainAnkyrin_rpt

ANKK1 FEM1B IBTK TRPC1 TRPV3 ANKRD18A ASB15

7.30e-05262737IPR002110
DomainDNA-bd_prot-inh

ID1 ID2

9.00e-054732IPR026052
DomainAnk_2

ANKK1 FEM1B IBTK TRPV3 ANKRD18A ASB15

1.94e-04215736PF12796
Domain4_helix_cytokine-like_core

GH1 GH2 CSH1 CSH2

2.01e-0474734IPR009079
DomainAcid_Pase_AS

PPIP5K1 PPIP5K2

2.24e-046732IPR033379
DomainAnk

ANKK1 FEM1B IBTK TRPV3 ANKRD18A ASB15

2.67e-04228736PF00023
DomainHIS_ACID_PHOSPHAT_2

PPIP5K1 PPIP5K2

3.12e-047732PS00778
DomainHIS_ACID_PHOSPHAT_1

PPIP5K1 PPIP5K2

3.12e-047732PS00616
DomainHis_Pase_clade-2

PPIP5K1 PPIP5K2

4.16e-048732IPR000560
DomainHis_Phos_2

PPIP5K1 PPIP5K2

4.16e-048732PF00328
DomainTPR_REGION

FEM1B SUGT1 TTC28 AIP FKBP5

4.69e-04165735PS50293
DomainTPR

FEM1B SUGT1 TTC28 AIP FKBP5

4.69e-04165735PS50005
Domain-

GH1 GH2 CSH1

9.84e-04507331.20.1250.10
DomainTPR_2

SUGT1 TTC28 AIP

9.84e-0450733PF07719
DomainTPR_2

SUGT1 TTC28 AIP

9.84e-0450733IPR013105
DomainFKBP_PPIASE

AIP FKBP5

1.75e-0316732PS50059
DomainFKBP_C

AIP FKBP5

1.75e-0316732PF00254
DomainTPR_repeat

SUGT1 TTC28 AIP FKBP5

1.83e-03133734IPR019734
DomainHATPase_c

MORC1 PDK2

2.21e-0318732SM00387
DomainHATPase_c

MORC1 PDK2

2.47e-0319732PF02518
DomainHis_PPase_superfam

PPIP5K1 PPIP5K2

2.74e-0320732IPR029033
Domain-

MORC1 PDK2

2.74e-03207323.30.565.10
DomainPPIase_FKBP_dom

AIP FKBP5

2.74e-0320732IPR001179
Domain-

PPIP5K1 PPIP5K2

2.74e-03207323.40.50.1240
DomainTPR-contain_dom

SUGT1 TTC28 AIP FKBP5

2.83e-03150734IPR013026
DomainHATPase_C

MORC1 PDK2

3.02e-0321732IPR003594
DomainTPR_1

SUGT1 TTC28 FKBP5

5.28e-0390733PF00515
DomainTPR_1

SUGT1 TTC28 FKBP5

5.28e-0390733IPR001440
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

GH1 GH2 CSH1 CSH2

1.79e-0713584MM14516
PathwayREACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

GH1 GH2 CSH1 CSH2

4.52e-0716584MM15710
PathwayBIOCARTA_LONGEVITY_PATHWAY

GH1 GH2 CSH1 CSH2

9.55e-0719584MM1513
PathwayREACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN

GH1 GH2 CSH1 CSH2

1.19e-0620584MM15070
PathwayBIOCARTA_AKT_PATHWAY

GH1 GH2 CSH1 CSH2

3.60e-0626584MM1345
PathwayBIOCARTA_TFF_PATHWAY

GH1 GH2 CSH1 CSH2

5.67e-0629584MM1522
PathwayBIOCARTA_GH_PATHWAY

GH1 GH2 CSH1 CSH2

9.66e-0633584MM1404
PathwayREACTOME_PROLACTIN_RECEPTOR_SIGNALING

GH1 GH2 CSH1

2.90e-0515583M552
PathwayREACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

GH1 GH2 CSH1

1.26e-0424583M519
PathwayWP_MIR517_RELATIONSHIP_WITH_ARCN1_AND_USP1

ID1 ID2

1.65e-045582M39330
PathwayREACTOME_PEPTIDE_HORMONE_METABOLISM

GH1 GH2 CSH1 CSH2

1.93e-0470584MM14916
PathwayREACTOME_TRP_CHANNELS

TRPM7 TRPC1 TRPV3

2.01e-0428583MM14943
PathwayREACTOME_TRP_CHANNELS

TRPM7 TRPC1 TRPV3

2.01e-0428583M27241
PathwayKEGG_MEDICUS_REFERENCE_GH_JAK_STAT_SIGNALING_PATHWAY

GH1 GH2

3.45e-047582M47646
PathwayREACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL

PPIP5K1 PPIP5K2

7.33e-0410582MM14709
PathwayREACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL

PPIP5K1 PPIP5K2

7.33e-0410582M27051
PathwayREACTOME_INTERLEUKIN_12_SIGNALING

JAK1 CFL1 AIP

9.42e-0447583M27894
PathwayREACTOME_INOSITOL_PHOSPHATE_METABOLISM

PPIP5K1 PPIP5K2 PLCE1

1.00e-0348583MM14589
PathwayREACTOME_INOSITOL_PHOSPHATE_METABOLISM

PPIP5K1 PPIP5K2 PLCE1

1.00e-0348583M26964
Pubmed

Regulation of Id2 expression in EL4 T lymphoma cells overexpressing growth hormone.

GH1 GH2 CSH1 CSH2 ID2

8.52e-13775519010462
Pubmed

Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells.

GH1 GH2 JAK1 CSH1 CSH2

5.10e-12975522467218
Pubmed

The human growth hormone gene family: nucleotide sequences show recent divergence and predict a new polypeptide hormone.

GH1 GH2 CSH1 CSH2

1.99e-1147547169009
Pubmed

Central growth hormone action regulates metabolism during pregnancy.

GH1 GH2 CSH1 CSH2

9.95e-11575431479305
Pubmed

Molecular evolution of growth hormone and receptor in the guinea-pig, a mammal unresponsive to growth hormone.

GH1 GH2 CSH1 CSH2

9.95e-11575410767558
Pubmed

Heterogeneous growth hormone (GH) gene mutations in familial GH deficiency.

GH1 GH2 CSH1 CSH2

9.95e-1157548496314
Pubmed

Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples.

GH1 GH2 CSH1 CSH2

9.95e-11575421045135
Pubmed

Analysis of gender difference of cardiac risk biomarkers using hGH-transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575416508206
Pubmed

Rescue of pituitary function in a mouse model of isolated growth hormone deficiency type II by RNA interference.

GH1 GH2 CSH1 CSH2

9.95e-11575418006625
Pubmed

Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia.

GH1 GH2 CSH1 CSH2

9.95e-11575415616010
Pubmed

Nitric oxide stimulates embryonic somatotroph differentiation and growth hormone mRNA and protein expression through a cyclic guanosine monophosphate-independent mechanism.

GH1 GH2 CSH1 CSH2

9.95e-11575419019400
Pubmed

The Effects of 20-kDa Human Placental GH in Male and Female GH-deficient Mice: An Improved Human GH?

GH1 GH2 CSH1 CSH2

9.95e-11575432556100
Pubmed

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice.

GH1 GH2 CSH1 CSH2

9.95e-1157541525063
Pubmed

Obesity and elevated plasma leptin concentration in oMT1A-o growth hormone transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575411346667
Pubmed

Cardiac contractile function is enhanced in isolated ventricular myocytes from growth hormone transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575412010633
Pubmed

Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis.

GH1 GH2 CSH1 CSH2

9.95e-11575417626886
Pubmed

Growth hormone prevents the development of autoimmune diabetes.

GH1 GH2 CSH1 CSH2

9.95e-11575424218587
Pubmed

Regulation of rapid signal transducer and activator of transcription-5 phosphorylation in the resting cells of the growth plate and in the liver by growth hormone and feeding.

GH1 GH2 CSH1 CSH2

9.95e-11575419359380
Pubmed

Body composition of inactivated growth hormone (oMt1a-oGH) transgenic mice: generation of an obese phenotype.

GH1 GH2 CSH1 CSH2

9.95e-1157549546108
Pubmed

Transgene transmission to progeny by oMt1a-oGH transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575416201410
Pubmed

Growth hormone stimulates the selective trafficking of thymic CD4+CD8- emigrants to peripheral lymphoid organs.

GH1 GH2 CSH1 CSH2

9.95e-11575415316240
Pubmed

Genes that prolong life: relationships of growth hormone and growth to aging and life span.

GH1 GH2 CSH1 CSH2

9.95e-11575411487592
Pubmed

Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575411318985
Pubmed

Involvement of insulin-like growth factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin.

GH1 GH2 CSH1 CSH2

9.95e-11575417301034
Pubmed

Growth hormone action in the developing neural retina: a proteomic analysis.

GH1 GH2 CSH1 CSH2

9.95e-11575418203262
Pubmed

Identification of the glomerular podocyte as a target for growth hormone action.

GH1 GH2 CSH1 CSH2

9.95e-11575417272398
Pubmed

Glucose homeostasis and insulin sensitivity in growth hormone-transgenic mice: a cross-sectional analysis.

GH1 GH2 CSH1 CSH2

9.95e-11575420707609
Pubmed

Assignment of the porcine growth hormone gene to chromosome 12.

GH1 GH2 CSH1 CSH2

9.95e-1157542249485
Pubmed

Growth hormone stimulates adipogenesis of 3T3-L1 cells through activation of the Stat5A/5B-PPARgamma pathway.

GH1 GH2 CSH1 CSH2

9.95e-11575417242167
Pubmed

A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.

GH1 GH2 CSH1 CSH2

9.95e-11575418180319
Pubmed

Induction of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-1157541874564
Pubmed

Cloning and characterisation of the GH gene from the common dolphin (Delphinus delphis).

GH1 GH2 CSH1 CSH2

9.95e-11575412225773
Pubmed

Growth Hormone Deficiency and Excess Alter the Gut Microbiome in Adult Male Mice.

GH1 GH2 CSH1 CSH2

9.95e-11575432100023
Pubmed

The related genes encoding growth hormone and prolactin have been dispersed to chromosomes 10 and 17 in the rat.

GH1 GH2 CSH1 CSH2

9.95e-1157543780533
Pubmed

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575410395045
Pubmed

Effect of genetic background on growth of mice hemizygous for wild-type or dwarf mutated bovine growth hormone transgenes.

GH1 GH2 CSH1 CSH2

9.95e-11575424190208
Pubmed

Brief report: short stature caused by a mutant growth hormone.

GH1 GH2 CSH1 CSH2

9.95e-1157548552145
Pubmed

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice.

GH1 GH2 CSH1 CSH2

9.95e-11575436762426
Pubmed

High molecular weight isoforms of growth hormone in cells of the immune system.

GH1 GH2 CSH1 CSH2

9.95e-11575421741628
Pubmed

Structure of the growth hormone-encoding gene and its promoter in mice.

GH1 GH2 CSH1 CSH2

9.95e-1157548647448
Pubmed

Thiol-Disulfide Exchange in Human Growth Hormone.

GH1 GH2 CSH1 CSH2

9.95e-11575426887678
Pubmed

Transgenic mice expressing bovine GH develop arthritic disorder and self-antibodies.

GH1 GH2 CSH1 CSH2

9.95e-11575410810296
Pubmed

The role of growth hormone in fetal mouse reproductive tract differentiation.

GH1 GH2 CSH1 CSH2

9.95e-1157548756530
Pubmed

GH Knockout Mice Have Increased Subcutaneous Adipose Tissue With Decreased Fibrosis and Enhanced Insulin Sensitivity.

GH1 GH2 CSH1 CSH2

9.95e-11575431099824
Pubmed

Somatotropin transgenic mice have reduced jejunal active glucose transport rates.

GH1 GH2 CSH1 CSH2

9.95e-1157547965203
Pubmed

Hot spots for growth hormone gene deletions in homologous regions outside of Alu repeats.

GH1 GH2 CSH1 CSH2

9.95e-1157541980158
Pubmed

Vitamin D3 cannot revert desensitization of growth hormone (GH)-induced STAT5-signaling in GH-overexpressing mice non-calcemic tissues.

GH1 GH2 CSH1 CSH2

9.95e-11575417881271
Pubmed

Neural growth hormone implicated in body weight sex differences.

GH1 GH2 CSH1 CSH2

9.95e-11575423861378
Pubmed

Growth hormone increases low-density lipoprotein receptor and HMG-CoA reductase mRNA expression in mesangial cells.

GH1 GH2 CSH1 CSH2

9.95e-11575412759574
Pubmed

Growth hormone production and action in N1E-115 neuroblastoma cells.

GH1 GH2 CSH1 CSH2

9.95e-11575419301152
Pubmed

Adipocyte insensitivity to insulin in growth hormone-transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575411350075
Pubmed

Transgenic mice overexpressing growth hormone (GH) have reduced or increased cardiac apoptosis through activation of multiple GH-dependent or -independent cell death pathways.

GH1 GH2 CSH1 CSH2

9.95e-11575418617616
Pubmed

Adipocytokines and the regulation of lipid metabolism in growth hormone transgenic and calorie-restricted mice.

GH1 GH2 CSH1 CSH2

9.95e-11575417347312
Pubmed

Growth hormone and fertility in oMt1a-oGH transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575411570960
Pubmed

Promoter shuffling has occurred during the evolution of the vertebrate growth hormone gene.

GH1 GH2 CSH1 CSH2

9.95e-11575410974531
Pubmed

Pleiotropic effects of growth hormone signaling in aging.

GH1 GH2 CSH1 CSH2

9.95e-11575421852148
Pubmed

Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.

GH1 GH2 CSH1 CSH2

9.95e-11575412175649
Pubmed

Transgenic mice reveal novel activities of growth hormone in wound repair, angiogenesis, and myofibroblast differentiation.

GH1 GH2 CSH1 CSH2

9.95e-11575415070902
Pubmed

Hepatocellular alterations and dysregulation of oncogenic pathways in the liver of transgenic mice overexpressing growth hormone.

GH1 GH2 CSH1 CSH2

9.95e-11575423428905
Pubmed

A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity.

GH1 GH2 CSH1 CSH2

9.95e-11575414726450
Pubmed

UV photodegradation of murine growth hormone: chemical analysis and immunogenicity consequences.

GH1 GH2 CSH1 CSH2

9.95e-11575424758742
Pubmed

Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.

GH1 GH2 CSH1 CSH2

9.95e-11575410076541
Pubmed

Overgrowth of skin in growth hormone transgenic mice depends on the presence of male gonads.

GH1 GH2 CSH1 CSH2

9.95e-11575410594738
Pubmed

Hypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytes.

GH1 GH2 CSH1 CSH2

9.95e-11575423639351
Pubmed

Pituitary growth hormone network responses are sexually dimorphic and regulated by gonadal steroids in adulthood.

GH1 GH2 CSH1 CSH2

9.95e-11575421098290
Pubmed

Cardiac expression of adenine nucleotide translocase-1 in transgenic mice overexpressing bovine GH.

GH1 GH2 CSH1 CSH2

9.95e-11575417761891
Pubmed

Age-related changes in body composition of bovine growth hormone transgenic mice.

GH1 GH2 CSH1 CSH2

9.95e-11575418948397
Pubmed

Localization of the panhypopituitary dwarf mutation (df) on mouse chromosome 11 in an intersubspecific backcross.

GH1 GH2 CSH1 CSH2 TNFAIP1

1.75e-10167551889803
Pubmed

Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5.

GH1 GH2 CSH1 CSH2 TNFAIP1

2.47e-10177557956352
Pubmed

The human growth hormone locus: nucleotide sequence, biology, and evolution.

GH1 GH2 CSH1 CSH2

2.98e-1067542744760
Pubmed

Growth hormone, acting in part through the insulin-like growth factor axis, rescues developmental, but not metabolic, activity in the mammary gland of mice expressing a single allele of the prolactin receptor.

GH1 GH2 CSH1 CSH2

2.98e-10675412399427
Pubmed

Transgenic mice over-expressing galanin exhibit pituitary adenomas and increased secretion of galanin, prolactin and growth hormone.

GH1 GH2 CSH1 CSH2

2.98e-10675414596666
Pubmed

GH modulates hepatic epidermal growth factor signaling in the mouse.

GH1 GH2 CSH1 CSH2

2.98e-10675420032199
Pubmed

Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2.

GH1 GH2 CSH1 CSH2

2.98e-10675411316754
Pubmed

The use of transgenic mice to analyze the role of accessory factor two in the regulation of phosphoenolpyruvate carboxykinase (GTP) gene transcription during diabetes.

GH1 GH2 CSH1 CSH2

2.98e-10675411309401
Pubmed

The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice.

GH1 GH2 CSH1 CSH2

2.98e-10675423150490
Pubmed

Nucleotide sequence of mouse prolactin and growth hormone mRNAs and expression of these mRNAs during pregnancy.

GH1 GH2 CSH1 CSH2

2.98e-1067542991252
Pubmed

Genetic dissection of IGF1-dependent and -independent effects of permanent GH excess on postnatal growth and organ pathology of mice.

GH1 GH2 CSH1 CSH2

2.98e-10675425017732
Pubmed

Third party data gene data set of eutherian growth hormone genes.

GH1 GH2 CSH1 CSH2

2.98e-10675426697363
Pubmed

Role of growth hormone in the genetic change of mice divergently selected for body weight and fatness.

GH1 GH2 CSH1 CSH2

2.98e-10675410689811
Pubmed

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse.

GH1 GH2 CSH1 CSH2

2.98e-10675415985453
Pubmed

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1a links growth hormone action to lipid metabolism in hepatocytes.

GH1 GH2 CSH1 CSH2

2.98e-10675420863500
Pubmed

An early reduction in GH peak amplitude in preproghrelin-deficient male mice has a minor impact on linear growth.

GH1 GH2 CSH1 CSH2

2.98e-10675424949662
Pubmed

Growth Hormone Pulses and Liver Gene Expression Are Differentially Regulated by the Circadian Clock Gene Bmal1.

GH1 GH2 CSH1 CSH2

2.98e-10675433539533
Pubmed

Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice.

GH1 GH2 CSH1 CSH2

2.98e-10675420231469
Pubmed

Growth hormone resistance: clinical states and animal models.

GH1 GH2 CSH1 CSH2

2.98e-10675410556764
Pubmed

Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling.

GH1 GH2 CSH1 CSH2

2.98e-10675412208853
Pubmed

Involvement of growth hormone as a regulating factor in sex differences of mouse hepatic aldehyde oxidase.

GH1 GH2 CSH1 CSH2

2.98e-1067549175714
Pubmed

Disruption of growth hormone signaling retards early stages of prostate carcinogenesis in the C3(1)/T antigen mouse.

GH1 GH2 CSH1 CSH2

2.98e-10675416141391
Pubmed

Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.

GH1 GH2 CSH1 CSH2

2.98e-10675418618017
Pubmed

Transcript abundance in mouse pituitaries with altered growth hormone expression quantified by reverse transcriptase polymerase chain reaction implicates transcription factor Zn-16 in gene regulation in vivo.

GH1 GH2 CSH1 CSH2

2.98e-10675412166626
Pubmed

Growth hormone expression in murine bone marrow cells is independent of the pituitary transcription factor Pit-1.

GH1 GH2 CSH1 CSH2

2.98e-1067549275086
Pubmed

Disruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH.

GH1 GH2 CSH1 CSH2

2.98e-10675423782652
Pubmed

Growth hormone is a positive regulator of adiponectin receptor 2 in 3T3-L1 adipocytes.

GH1 GH2 CSH1 CSH2

2.98e-10675414759511
Pubmed

Age related changes in gene expression within the cochlea of C57BL/6J mice.

GH1 GH2 CSH1 CSH2

2.98e-10675423010755
Pubmed

Acylated ghrelin is not required for the surge in pituitary growth hormone observed in pregnant mice.

GH1 GH2 CSH1 CSH2

2.98e-10675425645493
Pubmed

Administration of human insulin-like growth factor-binding protein-1 increases circulating levels of growth hormone in mice.

GH1 GH2 CSH1 CSH2

2.98e-10675415166120
Pubmed

Osteocalcin induces growth hormone/insulin-like growth factor-1 system by promoting testosterone synthesis in male mice.

GH1 GH2 CSH1 CSH2

2.98e-10675424691732
Pubmed

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.

GH1 GH2 CSH1 CSH2

2.98e-10675421725989
Pubmed

CTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment.

GH1 GH2 CSH1 CSH2

2.98e-10675438951485
InteractionSUGT1 interactions

SUGT1 UBE3A PDK2 CFL1 ANAPC2 AIP COPS5 FKBP5

1.19e-05293748int:SUGT1
InteractionCSH2 interactions

GH1 CSH1 CSH2

2.09e-0515743int:CSH2
InteractionGH1 interactions

GH1 CSH1 CSH2

2.57e-0516743int:GH1
InteractionCSH1 interactions

GH1 CSH1 CSH2

3.73e-0518743int:CSH1
Cytoband17q24.2

GH1 GH2 CSH1 CSH2

1.74e-073075417q24.2
CytobandEnsembl 112 genes in cytogenetic band chr17q23

GH1 GH2 CSH1 CSH2

4.67e-05120754chr17q23
GeneFamilyGrowth hormone family

GH1 GH2 CSH1 CSH2

7.73e-1065041175
GeneFamilyAnkyrin repeat domain containing

ANKK1 FEM1B IBTK TRPV3 ANKRD18A ASB15

5.25e-05242506403
GeneFamilyTransient receptor potential cation channels

TRPM7 TRPC1 TRPV3

6.21e-0528503249
GeneFamilyFKBP prolyl isomerases

AIP FKBP5

1.11e-0318502910
CoexpressionBREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP

GH1 GH2 SMG1 CSH1 CSH2

2.16e-0674745MM769
CoexpressionGRABARCZYK_BCL11B_TARGETS_UP

JAK1 NEK7 ID1 ID2 PPIP5K2

3.39e-0681745M6222
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

IBTK ATRX TTC28 ST3GAL5 UBE3A TRPC1 NEK7 ID1 MYO1B MSH2 PPIP5K2 PLCE1

4.65e-068567412M4500
CoexpressionWANG_LSD1_TARGETS_DN

GH1 GH2 CSH1 CSH2

7.99e-0645744MM740
CoexpressionHOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_DN

GH1 GH2 CSH1 CSH2

2.06e-0557744MM807
CoexpressionGSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_DN

FEM1B ARFRP1 SUGT1 RRN3 TXNDC16 COPS5

2.20e-05200746M9625
CoexpressionZAMORA_NOS2_TARGETS_UP

GH1 GH2 CSH1 CSH2

2.53e-0560744MM1165
ToppCellLeuk-UTI-Lymphocyte-T_NK-NK_CD56bright|Leuk-UTI / Disease, Lineage and Cell Type

JAK1 ATP6V1B1 ID2 ASB15 PRTFDC1

6.44e-06157745db0057741d06e212a9543cb4b011659b79efeafc
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MORC1 NEK7 ID2 SNAI3 PLCE1

1.15e-0517774544c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MORC1 SCN1B ID2 MYO1B FKBP5

1.32e-05182745b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MORC1 SCN1B ID2 FKBP5 SPATA13

1.43e-051857457d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 AGPAT3 ID2 SNAI3 SPATA13

1.46e-051867454dce1484653bb266e2305cbb306fb11eaf7892e2
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAK1 AGPAT3 ID2 SNAI3 SPATA13

1.46e-05186745e23e1246914e230369a716d0d666b98383bf8512
Druggadolinium

GH1 GH2 CSH1 CSH2 ST3GAL5 TRPM7 TRPC1 TRPV3 TNFAIP1

1.90e-08199759CID000023982
Drug3'dGTP

GH1 GH2 CSH2

1.52e-0515753CID000148770
DrugAC1L4OCG

GH2 JAK1 CSH2 TNFAIP1

2.41e-0551754CID000102535
Drugbeta-carene

GH2 CSH2

3.21e-053752CID000011129
Drugalpha-methylhomocysteine-thiolactone

GH1 GH2 CSH2 PLCE1

3.26e-0555754CID000133014
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A

ARFRP1 TTC28 PDK2 TRPC1 LHPP TNFAIP1

4.38e-051947562831_DN
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

FEM1B ARFRP1 ATRX HNMT FKBP5 CNOT8

4.50e-051957565213_DN
DrugGlycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A

FEM1B ARFRP1 TTC28 PDK2 TCP11L1 FKBP5

4.50e-051957563315_DN
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

ARFRP1 PDK2 AGPAT3 L2HGDH TNFAIP1 HNMT

4.50e-051957564368_DN
DrugLevamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; HL60; HG-U133A

FEM1B UBE3A RSF1 MSH2 PPIP5K2 HNMT

4.77e-051977561410_DN
DrugPheniramine maleate [132-20-7]; Down 200; 11.2uM; MCF7; HT_HG-U133A

FEM1B TTC28 PDK2 TRPC1 TNFAIP1 CNOT8

4.77e-051977561492_DN
DrugBenoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; HL60; HG-U133A

IBTK RSF1 NIPAL2 TNFAIP1 PPIP5K2 HNMT

4.90e-051987561976_UP
DrugICI 182,780; Up 200; 1uM; MCF7; HT_HG-U133A_EA

ARFRP1 ID1 NIPAL2 ID2 PRKG2 HNMT

5.04e-05199756985_UP
DrugVidarabine [5536-17-4]; Down 200; 15uM; MCF7; HT_HG-U133A

GTPBP4 ARFRP1 ST3GAL5 UBE3A TRPC1 HNMT

5.04e-051997563445_DN
DrugAmiloride hydrochloride dihydrate [17440-83-4]; Up 200; 13.2uM; MCF7; HT_HG-U133A

ATRX TTC28 VPS39 AGPAT3 ID2 HNMT

5.04e-051997561470_UP
DrugZr-C

GH2 CSH2

6.40e-054752CID000449163
Drug2-(ethylsulfonyl)ethanol

GH1 GH2 CSH1 CSH2 MSH2 COPS5

6.80e-05210756CID000010549
Diseaseisolated growth hormone deficiency type II (implicated_via_orthology)

GH1 GH2 CSH1 CSH2

1.82e-105744DOID:0060872 (implicated_via_orthology)
Diseaseisolated growth hormone deficiency (implicated_via_orthology)

GH1 GH2 CSH1 CSH2

1.27e-097744DOID:0060870 (implicated_via_orthology)
Diseasecongenital hypothyroidism (biomarker_via_orthology)

GH1 GH2 CSH1 CSH2

3.58e-0814744DOID:0050328 (biomarker_via_orthology)
Diseaseosteoporosis (biomarker_via_orthology)

GH1 GH2 CSH1 CSH2

2.58e-0722744DOID:11476 (biomarker_via_orthology)
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

GH1 GH2 CSH1 CSH2 SCN1B TRPC1

1.93e-06147746DOID:9352 (biomarker_via_orthology)
Diseasetype 1 diabetes mellitus (implicated_via_orthology)

GH1 GH2 CSH1 CSH2

2.80e-0639744DOID:9744 (implicated_via_orthology)
DiseaseInfiltrating duct carcinoma of female breast

ANKK1 SMG1 TRPM7

1.95e-0521743C3165106
Diseaselean body mass

GH1 TRPM7 PPFIA2 ANAPC2 PRKG2 PRTFDC1 PLCE1

4.69e-05379747EFO_0004995
DiseaseAcromegaly

GH1 AIP

6.17e-055742C0001206
DiseaseSomatotrophinoma, Familial

GH1 AIP

6.17e-055742C3489630
DiseaseGrowth Hormone-Secreting Pituitary Adenoma

GH1 AIP

6.17e-055742C0346302
DiseasePituitary Neoplasms

GH1 AIP

1.72e-048742C0032019
DiseaseRussell-Silver syndrome

GH2 CSH1

2.76e-0410742C0175693
DiseaseEpilepsy, Cryptogenic

UBE3A L2HGDH SYNGAP1

1.16e-0382743C0086237
DiseaseAwakening Epilepsy

UBE3A L2HGDH SYNGAP1

1.16e-0382743C0751111
DiseaseAura

UBE3A L2HGDH SYNGAP1

1.16e-0382743C0236018
DiseaseOvarian Serous Adenocarcinoma

TRPM7 NEK7

1.52e-0323742C1335177
Diseaseobsolete Mendelian syndromes with cleft lip/palate

TXNDC16 SPATA13

1.52e-0323742MONDO_0015335
DiseaseWeight Gain

GH1 NEK7 MYO1B

2.18e-03102743C0043094

Protein segments in the cluster

PeptideGeneStartEntry
YFKYCKISALALLKM

COPS5

51

Q92905
KMCLLQITGYKQLYL

ELMOD2

96

Q8IZ81
FVKMLPDKDCRYALY

CFL1

71

P23528
LMKEYNYLKEKLLQC

ANKRD18A

596

Q8IVF6
AYCKKYEQLKAMRTL

ANAPC2

621

Q9UJX6
AEAKYYLIQGLVNMC

TNFAIP1

106

Q13829
GKYLICKMLLRYGAS

ANKK1

571

Q8NFD2
LMKYGDSLYRCKQLK

GTPBP4

116

Q9BZE4
LIDYMDYVPLCAKLK

ASB15

501

Q8WXK1
ICLEKTKLYMAKYAD

CCNJ

171

Q5T5M9
GRIIKIYCADMYLEN

ADAMTS20

1736

P59510
KYYDAIACLKNLQMK

AIP

201

O00170
YSDIMVLCVLKGGYK

PRTFDC1

66

Q9NRG1
YLKEVMGLKCNTCIY

PATE4

16

P0C8F1
LKYAVQICKGMDYLG

JAK1

981

P23458
LLKVMGQYLVQYCKD

MORC1

426

Q86VD1
LNLAMCYLKLREYTK

FKBP5

321

Q13451
LYDMNGCYSRLKELV

ID1

66

P41134
NYCLGTKKYVLNEEM

FAR1

436

Q8WVX9
YATIKEEKGQCYLYM

MAK16

51

Q9BXY0
EMYKACFLGATVKYL

L2HGDH

371

Q9H9P8
IYLLADYQCKKMASK

IBTK

361

Q9P2D0
ERASGCKYLDYMQKI

LACTB

336

P83111
YGLLYCFRKDMDKVE

CSH2

186

P0DML3
NKYDNTCLMIAAYKG

FEM1B

151

Q9UK73
QMLDNLGLKYECYDL

HNMT

206

P50135
LELVKCGIQMYYELK

PDE6A

516

P16499
CGIQMYYELKVVDKF

PDE6A

521

P16499
FYGDKMNLYSLCKKI

NEK7

236

Q8TDX7
PYMKALEYACGIKAE

LHPP

171

Q9H008
KDNKYVYMLLEACLG

PRKG2

521

Q13237
VKDAYDMAKLLCDKY

PDK2

201

Q15119
AVLMERLCKYIYAKD

EIF3CL

546

B5ME19
YMFQKDEYCILILGL

ARFRP1

11

Q13795
ILYEMLAGCVQRKDY

ATRX

1806

P46100
ELKKVCQEMYLTYGD

DYNC1H1

2181

Q14204
SIYDVKYLMKSCKNL

CNOT8

191

Q9UFF9
YGLLYCFRKDMDKVE

CSH1

186

P0DML2
YLEMSVECKLALLKY

RSF1

111

Q96T23
QGYDIMEPAAKKCYL

MSH2

861

P43246
YGIMCLKRLNYDRKE

PPFIA2

1076

O75334
VLSYMKDVCYVDGKV

RRN3

321

Q9NYV6
KMVFCPYYDAILSKI

TCP11L1

491

Q9NUJ3
LYACYAIGKDVQAMK

ATP6V1B1

416

P15313
QGLKTLMSDIQYYCK

TDRD6

796

O60522
QKKNYVAYTCKLMEL

PLCE1

226

Q9P212
LIFCILLYFYKRKGM

NIPAL2

191

Q9H841
LYNMNDCYSKLKELV

ID2

36

Q02363
EKLMYNAYEGCANAL

SMG1

991

Q96Q15
YILKLNYTTEECDMK

ST3GAL5

81

Q9UNP4
KATACQMLVYYAKEL

RANBP6

686

O60518
LIRSLQKKDSGMYYC

SEMA3D

651

O95025
KYCDKEYTSLGALKM

SNAI3

186

Q3KNW1
FLGCSYNKDLLDKVM

CDKN2AIPNL

76

Q96HQ2
CKKDLLRRDMLYYKG

SPATA13

486

Q96N96
FLLACDKGDYYMVKK

TRPC1

51

P48995
YGLLYCFRKDMDKVE

GH2

186

P01242
RYCGKEKDLMKAYLF

TXNDC16

91

Q9P2K2
KQLLCEALYLYGVML

WASHC5

136

Q12768
DAIVAASKCLKMVYY

UBE3A

366

Q05086
ASKCLKMVYYANVVG

UBE3A

371

Q05086
KALKLLDYVMCDYRS

TRAPPC11

471

Q7Z392
LGILYGKKYEADMCV

AGPAT3

241

Q9NRZ7
PKKRYYCELCLDDML

SYNGAP1

276

Q96PV0
KYLDKASYRVFCLMG

TKTL2

141

Q9H0I9
AEMIYCYKKIAAATE

SCN1B

176

Q07699
SLCVNKEERGMKIYY

FAM170A

116

A1A519
LYKDVMLDNCKYLAS

ZNF840P

66

A6NDX5
YGLLYCFRKDMDKVE

GH1

186

P01241
AMLRKGICEYHEKNY

SUGT1

81

Q9Y2Z0
ALGKYTMAFKCYEEQ

TTC28

806

Q96AY4
LFAYKEYLACLVLAM

TRPV3

541

Q8NET8
SMKYYDDCAKILGNI

PPIP5K2

331

O43314
KALVACKIYRSMAYE

TRPM7

651

Q96QT4
NSMKYYDDCAKILGN

PPIP5K1

341

Q6PFW1
YCEKVQGLMKEYLLS

VPS39

626

Q96JC1
QAYEPCLERYKMLCK

MYO1B

636

O43795