Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonuclease III activity

DROSHA DICER1

2.48e-053582GO:0004525
GeneOntologyMolecularFunctiondouble-stranded RNA-specific ribonuclease activity

DROSHA DICER1

2.48e-053582GO:0032296
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

DROSHA GEN1 DICER1

3.23e-0446583GO:0016893
DomainRibonuclease_3

DROSHA DICER1

2.84e-053582PF00636
DomainRIBOc

DROSHA DICER1

2.84e-053582SM00535
DomainRNase_III_dom

DROSHA DICER1

2.84e-053582IPR000999
DomainRNASE_3_1

DROSHA DICER1

2.84e-053582PS00517
DomainRNASE_3_2

DROSHA DICER1

2.84e-053582PS50142
Domain-

DROSHA DICER1

2.84e-0535821.10.1520.10
DomainRoc

IFT22 LRRK1

7.23e-0413582PF08477
DomainMIRO-like

IFT22 LRRK1

7.23e-0413582IPR013684
DomainAminotransferase_I/II

GOT1L1 KYAT3

1.25e-0317582IPR004839
DomainAminotran_1_2

GOT1L1 KYAT3

1.25e-0317582PF00155
DomainDSRM

DROSHA DICER1

1.57e-0319582SM00358
Domaindsrm

DROSHA DICER1

1.74e-0320582PF00035
DomainDS_RBD

DROSHA DICER1

1.92e-0321582PS50137
DomainLIPASE_SER

PNLIPRP2 LCAT

2.94e-0326582PS00120
Domain-

DROSHA DICER1

3.16e-03275823.30.160.20
DomaindsRBD_dom

DROSHA DICER1

3.40e-0328582IPR014720
DomainARM-type_fold

PIK3CD USP9X TTC12 USP9Y ECPAS

3.99e-03339585IPR016024
Domain-

GOT1L1 KYAT3

5.28e-03355823.90.1150.10
DomainPyrdxlP-dep_Trfase_major_sub2

GOT1L1 KYAT3

5.58e-0336582IPR015422
DomainWHTH_DNA-bd_dom

FOXO3 FOXL2 PSMD12 ELL

6.75e-03242584IPR011991
DomainPyrdxlP-dep_Trfase

GOT1L1 KYAT3

7.19e-0341582IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

GOT1L1 KYAT3

7.19e-0341582IPR015421
DomainBTB-kelch_protein

KLHL13 KLHL15

7.89e-0343582IPR017096
DomainTF_fork_head_CS_2

FOXO3 FOXL2

8.99e-0346582IPR030456
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_4

LMF1 PDIA2 LCAT

3.91e-0522433M42574
PathwayKEGG_MEDICUS_PATHOGEN_EBV_LMP2A_TO_PI3K_SIGNALING_PATHWAY

PIK3CD LYN

9.04e-055432M48997
PathwayWP_EXRNA_MECHANISM_OF_ACTION_AND_BIOGENESIS

DROSHA DICER1

1.35e-046432M39578
PathwayWP_MIRNA_BIOGENESIS

DROSHA DICER1

1.35e-046432M39416
Pubmed

Lack of mutation of DICER1 and FOXL2 genes in microcystic stromal tumor of the ovary.

FOXL2 DICER1

2.73e-06258227830327
Pubmed

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development.

DROSHA DICER1

2.73e-06258226718009
Pubmed

DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors.

DROSHA DICER1

2.73e-06258226906421
Pubmed

Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells.

DROSHA DICER1

2.73e-06258234576018
Pubmed

Knock-down of core proteins regulating microRNA biogenesis has no effect on sensitivity of lung cancer cells to ionizing radiation.

DROSHA DICER1

2.73e-06258222479364
Pubmed

Upregulation of microRNA processing enzymes Drosha and Dicer in gestational diabetes mellitus.

DROSHA DICER1

2.73e-06258225295740
Pubmed

Evaluating the Effect of 3'-UTR Variants in DICER1 and DROSHA on Their Tissue-Specific Expression by miRNA Target Prediction.

DROSHA DICER1

2.73e-06258234287278
Pubmed

Differences in the Drosha and Dicer Cleavage Profiles in Colorectal Cancer and Normal Colon Tissue Samples.

DROSHA DICER1

2.73e-06258232894467
Pubmed

The effects of DICER1 and DROSHA polymorphisms on susceptibility to recurrent spontaneous abortion.

DROSHA DICER1

2.73e-06258231659796
Pubmed

Dicer, Drosha, and outcomes in patients with ovarian cancer.

DROSHA DICER1

2.73e-06258219092150
Pubmed

FTO interacts with FOXO3a to enhance its transcriptional activity and inhibits aggression in gliomas.

FOXO3 FTO

2.73e-06258232724043
Pubmed

Dysregulated expression of dicer and drosha in breast cancer.

DROSHA DICER1

2.73e-06258221898071
Pubmed

The expression of Dicer and Drosha in matched normal tissues, tumours and lymph node metastases in triple negative breast cancer.

DROSHA DICER1

2.73e-06258224725360
Pubmed

Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors.

FOXL2 DICER1

2.73e-06258232910017
Pubmed

Expression of DROSHA and DICER genes in peripheral blood leukocytes in lung sarcoidosis.

DROSHA DICER1

2.73e-06258230701851
Pubmed

siRNA release from pri-miRNA scaffolds is controlled by the sequence and structure of RNA.

DROSHA DICER1

2.73e-06258226921501
Pubmed

Alternative initiation and splicing in dicer gene expression in human breast cells.

DROSHA DICER1

2.73e-06258215987463
Pubmed

Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus.

DROSHA DICER1

2.73e-06258218434510
Pubmed

Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT) Commonly Exhibits Positivity With Sex Cord Markers FOXL2 and SF-1 but Lacks FOXL2 and DICER1 Mutations.

FOXL2 DICER1

2.73e-06258226598979
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

2.73e-06258212925892
Pubmed

Perturbation of DROSHA and DICER expression by human papillomavirus 16 oncoproteins.

DROSHA DICER1

2.73e-06258228448850
Pubmed

Dicer and Drosha expression and response to Bevacizumab-based therapy in advanced colorectal cancer patients.

DROSHA DICER1

2.73e-06258223266047
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

2.73e-06258212895410
Pubmed

DICER1, DROSHA and miRNAs in patients with non-small cell lung cancer: implications for outcomes and histologic classification.

DROSHA DICER1

2.73e-06258223349018
Pubmed

DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study.

FOXL2 DICER1

2.73e-06258226033501
Pubmed

Sequence features of Drosha and Dicer cleavage sites affect the complexity of isomiRs.

DROSHA DICER1

2.73e-06258225867481
Pubmed

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours.

DROSHA DICER1

2.73e-06258225190313
Pubmed

DICER and DROSHA gene expression and polymorphisms in autoimmune thyroid diseases.

DROSHA DICER1

2.73e-06258227808570
Pubmed

Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer.

DROSHA DICER1

2.73e-06258220210522
Pubmed

Murine follicular development requires oocyte DICER, but not DROSHA.

DROSHA DICER1

2.73e-06258224990804
Pubmed

DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.

DROSHA DICER1

2.73e-06258233535080
Pubmed

The 3' UTR polymorphisms rs3742330 in DICER1 and rs10719 in DROSHA genes are not associated with primary open-angle and angle-closure glaucoma: As case-control study.

DROSHA DICER1

2.73e-06258237099569
Pubmed

The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.

DROSHA DICER1

2.73e-06258221544061
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

2.73e-0625828922996
Pubmed

Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer.

DROSHA DICER1

2.73e-06258221559780
Pubmed

Dynamic microRNA gene transcription and processing during T cell development.

DROSHA DICER1

2.73e-06258222379031
Pubmed

High copy number variation of cancer-related microRNA genes and frequent amplification of DICER1 and DROSHA in lung cancer.

DROSHA DICER1

2.73e-06258226156018
Pubmed

A role for Dicer in immune regulation.

DROSHA DICER1

2.73e-06258217060477
Pubmed

Association of rs1057035polymorphism in microRNA biogenesis pathway gene (DICER1) with azoospermia among Iranian population.

DROSHA DICER1

2.73e-06258229892896
Pubmed

Genetic variants in microRNA biogenesis pathway genes are associated with semen quality in a Han-Chinese population.

DROSHA DICER1

2.73e-06258222381205
Pubmed

microRNA signature and expression of Dicer and Drosha can predict prognosis and delineate risk groups in neuroblastoma.

DROSHA DICER1

2.73e-06258220805302
Pubmed

The microRNA-processing enzymes: Drosha and Dicer can predict prognosis of nasopharyngeal carcinoma.

DROSHA DICER1

2.73e-06258221953080
Pubmed

DICER1 and FOXL2 Mutation Status Correlates With Clinicopathologic Features in Ovarian Sertoli-Leydig Cell Tumors.

FOXL2 DICER1

2.73e-06258230986800
Pubmed

Overexpression of microRNA biogenesis machinery: Drosha, DGCR8 and Dicer in multiple sclerosis patients.

DROSHA DICER1

8.19e-06358225439752
Pubmed

MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production.

DROSHA DICER1

8.19e-06358224938790
Pubmed

EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.

DROSHA DICER1

8.19e-06358225656609
Pubmed

Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.

DROSHA DICER1

8.19e-06358222706270
Pubmed

Association between Genetic Polymorphisms in microRNA Machinery Genes and Risk of Papillary Thyroid Carcinoma.

DROSHA DICER1

8.19e-06358231250375
Pubmed

Genetic variants in microRNA machinery genes are associated [corrected] with idiopathic recurrent pregnancy loss risk.

DROSHA DICER1

8.19e-06358224769857
Pubmed

Immunohistochemical analysis of the endoribonucleases Drosha, Dicer and Ago2 in smooth muscle tumours of soft tissues.

DROSHA DICER1

8.19e-06358222394132
Pubmed

The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis.

DROSHA DICER1

8.19e-06358222665486
Pubmed

Re-evaluation of the roles of DROSHA, Export in 5, and DICER in microRNA biogenesis.

DROSHA DICER1

8.19e-06358226976605
Pubmed

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells.

DROSHA DICER1

8.19e-06358230295958
Pubmed

Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis.

DROSHA DICER1

8.19e-06358226437240
Pubmed

Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin.

DROSHA DICER1

8.19e-06358222434867
Pubmed

Complexity in regulation of microRNA machinery components in invasive breast carcinoma.

DROSHA DICER1

8.19e-06358224574065
Pubmed

Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients.

DROSHA DICER1

8.19e-06358222371183
Pubmed

Expression of the microRNA regulators Drosha, Dicer and Ago2 in non-small cell lung carcinomas.

DROSHA DICER1

8.19e-06358226227789
Pubmed

Pineoblastoma is uniquely tolerant of mutually exclusive loss of DICER1, DROSHA or DGCR8.

DROSHA DICER1

8.19e-06358232124011
Pubmed

Canonical and alternate functions of the microRNA biogenesis machinery.

DROSHA DICER1

8.19e-06358220713509
Pubmed

Investigation of AID, Dicer, and Drosha Expressions in Patients with Chronic Lymphocytic Leukemia.

DROSHA DICER1

8.19e-06358228388279
Pubmed

Drosha, DGCR8, and Dicer mRNAs are down-regulated in human cells infected with dengue virus 4, and play a role in viral pathogenesis.

DROSHA DICER1

8.19e-06358227173348
Pubmed

Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder.

DROSHA DICER1

8.19e-06358222766726
Pubmed

Reduced Foxo3a, FoxL2, and p27 mRNA expression in human ovarian tissue in premature ovarian insufficiency.

FOXO3 FOXL2

8.19e-06358231637660
Pubmed

The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping.

DROSHA DICER1

8.19e-06358234855193
Pubmed

Male germ cells express abundant endogenous siRNAs.

DROSHA DICER1

8.19e-06358221788498
Pubmed

Expression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomas.

DROSHA DICER1

8.19e-06358221769619
Pubmed

Transcript Level of MicroRNA Processing Elements in Gastric Cancer.

DROSHA DICER1

8.19e-06358230168106
Pubmed

Arginine methylation of USP9X promotes its interaction with TDRD3 and its anti-apoptotic activities in breast cancer cells.

TDRD3 USP9X

8.19e-06358228101374
Pubmed

Expression of genes for microRNA-processing enzymes is altered in advanced non-alcoholic fatty liver disease.

DROSHA DICER1

8.19e-06358223663110
Pubmed

Dicer and Drosha expression in patients with nephrotic syndrome.

DROSHA DICER1

1.64e-05458232412691
Pubmed

Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.

DROSHA DICER1

1.64e-05458222647351
Pubmed

Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis.

DROSHA DICER1

1.64e-05458220699384
Pubmed

Ars2 maintains neural stem-cell identity through direct transcriptional activation of Sox2.

DROSHA DICER1

1.64e-05458222198669
Pubmed

PTPIP51 is phosphorylated by Lyn and c-Src kinases lacking dephosphorylation by PTP1B in acute myeloid leukemia.

PTPN1 LYN

1.64e-05458221513978
Pubmed

3'-UTR Polymorphisms in the MiRNA Machinery Genes DROSHA, DICER1, RAN, and XPO5 Are Associated with Colorectal Cancer Risk in a Korean Population.

DROSHA DICER1

1.64e-05458226147304
Pubmed

Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB.

DROSHA DICER1

1.64e-05458227545503
Pubmed

Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease.

DROSHA DICER1

1.64e-05458232770606
Pubmed

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation.

DROSHA DICER1

2.72e-05558227880903
Pubmed

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.

DROSHA DICER1

2.72e-05558218725527
Pubmed

BRG1 and SMARCAL1 transcriptionally co-regulate DROSHA, DGCR8 and DICER in response to doxorubicin-induced DNA damage.

DROSHA DICER1

2.72e-05558228716689
Pubmed

The circulating microRNome demonstrates distinct lymphocyte subset-dependent signatures.

TAP1 DICER1

2.72e-05558226639063
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

TDRD3 SGMS1 MAPKAPK3 PSMD12 FTO DICER1 DENR

3.03e-0553658715840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

TDRD3 SGMS1 MAPKAPK3 PSMD12 FTO DICER1 DENR

3.10e-0553858710512203
Pubmed

A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

FOXO3 MRC1 BAZ1A SLC17A4 DICER1

3.23e-0521858519460752
Pubmed

Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.

FOXO3 PIK3CD

4.08e-05658217618288
Pubmed

Asynchronous embryonic germ cell development leads to a heterogeneity of postnatal ovarian follicle activation and may influence the timing of puberty onset in mice.

FOXO3 FOXL2

4.08e-05658235550124
Pubmed

Upregulation of Cyclin B1 by miRNA and its implications in cancer.

DROSHA DICER1

4.08e-05658222053081
Pubmed

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets.

DROSHA DICER1

4.08e-05658226773046
Pubmed

Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases.

PTPN1 LYN

5.71e-05758226457672
Pubmed

Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes.

DROSHA DICER1

7.60e-05858220211803
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

FOXO3 IFT22 IRAK1 ECPAS LYN DNAH7 ELL GGA3

8.21e-0585358828718761
Pubmed

Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.

PDIA2 TAP1

9.77e-05958217055437
Pubmed

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment.

DROSHA DICER1

9.77e-05958218604195
Pubmed

Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.

DROSHA DICER1

1.22e-041058220721975
Pubmed

Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.

USP9X USP9Y

1.22e-04105829384609
Pubmed

Targeting of protein ubiquitination by BTB-Cullin 3-Roc1 ubiquitin ligases.

KLHL13 KLHL15

1.49e-041158214528312
Pubmed

The fused toes locus is essential for somatic-germ cell interactions that foster germ cell maturation in developing gonads in mice.

FOXL2 FTO

1.49e-041158221293032
Pubmed

Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis.

USP9X USP9Y

1.78e-041258223861879
Pubmed

Lessons on conditional gene targeting in mouse adipose tissue.

PTPN1 DICER1

1.78e-041258223321074
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

FOXO3 PTPN1 TDRD3 DMXL2 SGMS1 BAZ1A USP9X FTO LYN DICER1

1.65e-058565810M4500
CoexpressionMARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP

FOXO3 FOXL2 MAPKAPK3 NAV1 TAP1

4.55e-05177585M5681
CoexpressionMARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP

FOXO3 FOXL2 MAPKAPK3 NAV1 TAP1

5.61e-05185585MM1115
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_DN

RAPGEF5 AGL SLC17A4 APLP2 LYN

7.74e-05198585M9407
CoexpressionGSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN

SGMS1 APLP2 IL17RC LRRK1 DENR

8.12e-05200585M6485
CoexpressionGSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN

PIK3CD DROSHA KLHL15 APLP2 IL17RC

8.12e-05200585M6550
CoexpressionGSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_UP

AGL KLHL13 ELAPOR1 ELL EDNRB

8.12e-05200585M7335
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_200

MRC1 RAMP2 HPGDS RAPGEF5 LYN EDNRB

1.02e-05182586gudmap_dev gonad_e11.5_F_ReproVasc_Flk_200
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_500

MRC1 RAMP2 HPGDS LYN EDNRB

1.43e-05113585gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k2_500
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_200

MRC1 RAMP2 RAPGEF5 LYN EDNRB

6.72e-05156585gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k2_200
CoexpressionAtlaskidney_e15.5_SmlBldVes_Tie2_top-relative-expression-ranked_100

MRC1 RAMP2 LYN EDNRB

9.85e-0588584gudmap_kidney_e15.5_SmlBldVes_Tie2_100
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#3_top-relative-expression-ranked_500

MRC1 RAMP2 HPGDS LYN EDNRB

1.01e-04170585gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k3_500
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_500

MRC1 RAMP2 HPGDS RAPGEF5 LYN EDNRB

1.18e-04282586gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_500
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_200

MRC1 RAMP2 RAPGEF5 LYN EDNRB

1.19e-04176585gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_200
CoexpressionAtlaskidney_e15.5_SmlBldVes_Tie2_top-relative-expression-ranked_200

MRC1 RAMP2 RAPGEF5 LYN EDNRB

1.28e-04179585gudmap_kidney_e15.5_SmlBldVes_Tie2_200
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_200

MRC1 RAMP2 RAPGEF5 LYN EDNRB

1.32e-04180585gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_200
CoexpressionAtlasdev gonad_e11.5_M_ReproVasc_Flk_top-relative-expression-ranked_200

MRC1 RAMP2 HPGDS LYN EDNRB

1.39e-04182585gudmap_dev gonad_e11.5_M_ReproVasc_Flk_200
CoexpressionAtlaskidney_e15.5_SmlBldVes_Tie2_k-means-cluster#2_top-relative-expression-ranked_200

RAMP2 RAPGEF5 LYN EDNRB

1.44e-0497584gudmap_kidney_e15.5_SmlBldVes_Tie2_k2_200
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_top-relative-expression-ranked_500

MRC1 RAMP2 HPGDS RAPGEF5 NAV1 LYN EDNRB

1.64e-04430587gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_500
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#3_top-relative-expression-ranked_200

MRC1 RAMP2 EDNRB

1.92e-0441583gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k3_200
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#4_top-relative-expression-ranked_200

MRC1 HPGDS EDNRB

2.21e-0443583gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k4_200
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_200

MRC1 RAMP2 RAPGEF5 LYN

2.33e-04110584gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k2_200
CoexpressionAtlaskidney_e15.5_SmlBldVes_Tie2_k-means-cluster#1_top-relative-expression-ranked_100

RAMP2 LYN EDNRB

2.88e-0447583gudmap_kidney_e15.5_SmlBldVes_Tie2_k1_100
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_1000

MRC1 PTPN1 RAMP2 BAZ1A HPGDS RAPGEF5 NAV1 LYN EDNRB

3.47e-04817589gudmap_dev gonad_e11.5_F_ReproVasc_Flk_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

TDRD3 PNLIPRP2 KLHL13 KYAT3 DNAH7

3.63e-04224585gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_1000

MRC1 RAMP2 BAZ1A HPGDS RAPGEF5 LYN EDNRB

5.36e-04523587gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k4_1000
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_k-means-cluster#4_top-relative-expression-ranked_500

RAMP2 RAPGEF5 LYN EDNRB

5.37e-04137584gudmap_kidney_adult_GlomCapSys_Tie2_k4_500
CoexpressionAtlaskidney_adult_GlomCapSys_Tie2_k-means-cluster#1_top-relative-expression-ranked_200

RAMP2 LYN EDNRB

5.93e-0460583gudmap_kidney_adult_GlomCapSys_Tie2_k1_200
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RAMP2 SGMS1 RAPGEF5 APLP2 EDNRB

2.06e-071955867f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

4.87e-06190585788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

4.99e-06191585baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 LYN EDNRB

5.39e-06194585fc40ab57be3a15c043e3414c2c678c1dc52207c8
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 LYN EDNRB

5.39e-0619458550fa7c7940b113427c87fbdb9057fef8e1ce52c5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.39e-061945851dce6d4b6ac41f80677e3e4c335a4f383bd76f85
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.52e-061955852d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.52e-06195585ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.52e-0619558509df40ff9b493170861b3f6e57a942a834655b5c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.52e-0619558534a9462f4e843f3065cc58c17ad71c1b5b836ae1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.66e-061965854370473693d2dd4a8c451a4c477eb79baa33ae12
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RAMP2 SGMS1 RAPGEF5 NAV1

5.81e-06197585deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RAMP2 SGMS1 RAPGEF5 NAV1

5.81e-06197585a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LRRK1 LYN

5.95e-0619858596883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RAMP2 SGMS1 RAPGEF5 NAV1

5.95e-06198585f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 RGSL1 CYP2R1 HPGDS

5.49e-05159584c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCA1B PIK3CD AGL KLHL15

6.05e-051635847a04192710f55acf5a4681d5f09942358fdb02ff
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 GUCA1B LRRK1 LYN

7.45e-051725841f335ccb92b22d0412954e8fc3af212f96410b67
ToppCelldroplet-Liver-nan-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 GUCA1B LRRK1 LYN

7.45e-05172584bb96c896d125e10b71e94e2bdad243899045af5c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO3 PTPN1 BAZ1A EDNRB

7.96e-05175584910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO3 PTPN1 BAZ1A EDNRB

7.96e-05175584f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 HPGDS LYN ELL

7.96e-05175584c9dc6aa652ac887470806a950311657c423d9495
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 DMXL2 BAZ1A PIK3CD

8.14e-05176584270d7908dbd84028958d257f94941dc685e20255
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRC1 DMXL2 BAZ1A HPGDS

9.27e-0518258457f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DMXL2 IRAK1 APLP2 EDNRB

9.67e-05184584e343dd7777a29048e3f12a939f7f782b8b7b4fea
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RAMP2 NAV1 EDNRB

9.87e-05185584742350093d90f96735dc73e3360cdd749bae63fd
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DMXL2 BAZ1A LYN TAP1

9.87e-05185584f30fb9d75cdb757b206312992aaf7485bc900f96
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 SGMS1 APLP2 EDNRB

9.87e-05185584a32d5cb596ebac80eb1ac301055e65d420879ec8
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Angpt2_(Angpt2)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 FOXL2 PNLIPRP2

1.00e-046958373b7accba3060705dcd6240e0ff47d68f2014ddd
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Angpt2_(Angpt2)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 FOXL2 PNLIPRP2

1.00e-04695834e2e86e1da2ded562252774dc49e1b0b4274259f
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Angpt2_(Angpt2)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 FOXL2 PNLIPRP2

1.00e-04695833b1b8b8f85440a7a88d52969bdff384a0c1a5470
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

PTPN1 GOT1L1 NAV1 LRRK1

1.01e-041865840987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MRC1 DMXL2 APLP2 EDNRB

1.01e-04186584f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 RAPGEF5 APLP2 EDNRB

1.01e-041865840ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MRC1 DMXL2 APLP2 EDNRB

1.01e-041865848694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 KCNF1 NAV1 EDNRB

1.05e-0418858451c6796a9488c056a10d048082015342c2e037f9
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 KCNF1 NAV1 EDNRB

1.05e-04188584b651024d58ed1bcfe0d80b21755f8bf709eda81f
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 DMXL2 BAZ1A APLP2

1.07e-04189584b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCellPND01-03-samps-Endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

RAMP2 RAPGEF5 NAV1 EDNRB

1.09e-041905841357bd4527399d7013ee33272bda7453f472999a
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MRC1 DMXL2 BAZ1A APLP2

1.09e-04190584da58227565ad6a690828dd8554dd3670222f8582
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 SGMS1 USP9X APLP2

1.09e-041905841d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

RAMP2 RAPGEF5 NAV1 EDNRB

1.09e-041905845130fb325f80f591b9b36beacb8072c4472304f2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LYN

1.12e-0419158451f5af610983aa73b9f4ece6f27d281ebff89a04
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

MRC1 DMXL2 BAZ1A APLP2

1.12e-041915847bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

PIK3CD NAV1 LRRK1 LYN

1.12e-04191584cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPN1 DMXL2 IRAK1 LYN

1.12e-041915840b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 HPGDS PIK3CD LYN

1.12e-041915848fd6bdc9d2b1c8d364221d7bc68d03921b668ab5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.12e-04191584718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.12e-04191584454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DMXL2 APLP2 ECPAS LYN

1.12e-04191584c9f3bdb5c0a90268cab24a0fe4c3a8290fcedeb8
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

MRC1 DMXL2 PIK3CD LYN

1.14e-04192584a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 SGMS1 APLP2 EDNRB

1.14e-0419258424d28e28a5c54ca7770f7e5ad7f4d00039e0aaf9
ToppCellfacs-Lung-Endomucin_-18m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 SGMS1 RAPGEF5 APLP2

1.14e-04192584ba3fe97786564dba1c8185f2802ce1b57f4f3cc9
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DMXL2 APLP2 ECPAS LYN

1.14e-04192584b86476037ddf8904c1d8a6b3763af7242c031cf3
ToppCellfacs-Lung-Endomucin_|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 SGMS1 RAPGEF5 APLP2

1.14e-0419258485d4d0df701451daf95e94a87a0096da1e86533b
ToppCellEndothelial|World / shred on cell class and cell subclass (v4)

RAMP2 RAPGEF5 NAV1 EDNRB

1.14e-041925842b13cca5c4b58628dbbbb356859632dba66d43f9
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HPGDS RAPGEF5 USP9X EDNRB

1.14e-041925841ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAMP2 RAPGEF5 NAV1 EDNRB

1.16e-04193584f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

MRC1 DMXL2 PIK3CD LYN

1.16e-0419358412bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCellPND10-Endothelial-Endothelial_blood-vessel|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.16e-041935841d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MRC1 RAMP2 KCNF1 EDNRB

1.16e-04193584bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCellfacs-Liver-Non-hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRC1 RAMP2 SGMS1 RAPGEF5

1.16e-041935848084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 IRAK1 APLP2 LYN

1.16e-0419358493ba635ed69fec9286fe7636b9d258f3d93a22c3
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.16e-04193584097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MRC1 IRAK1 APLP2 LYN

1.16e-041935846dfdeb793cb5ad6412b6f808b5687a4e74b6ec65
ToppCellPND10-Endothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.16e-04193584f3c743b340fc588bc8effd375b12e2c7cbfa49d2
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RAMP2 RAPGEF5 TAP1 EDNRB

1.16e-04193584aaf681f16f310168e4719464814a1fc0a2f8431a
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Activated_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

PTPN1 RAMP2 NAV1 LRRK1

1.19e-04194584219056d4ad256cda73208b8c570bbf689219df83
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 SGMS1 RAPGEF5 APLP2

1.19e-04194584f159ef8541d75a4e98468947f231bb463bec922c
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MRC1 IRAK1 APLP2 LYN

1.19e-04194584e455cb469157c044126f9b0b308957d4ee1e608b
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

FOXO3 MRC1 PTPN1 DMXL2

1.19e-041945847d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellLPS-IL1RA-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAMP2 RAPGEF5 NAV1 EDNRB

1.19e-0419458443f92b0533e26633dc94cce554045d641ef8fd76
ToppCellControl-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

FOXO3 MRC1 DMXL2 IRAK1

1.19e-04194584c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 NAV1 LYN EDNRB

1.19e-041945848deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCellLPS-IL1RA-Endothelial-Endothelial|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAMP2 RAPGEF5 NAV1 EDNRB

1.19e-041945841d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MRC1 IRAK1 APLP2 LYN

1.19e-04194584e0cfd18a7ea2251163d61312b9397f8a518c8c51
ToppCellTCGA-Blood_and_Bone_Marrow-Primary_Tumor-Diffuse_large_B-cell_lymphoma-DLBCL-1|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9

PTPN1 MXRA5 RAPGEF5 TAP1

1.19e-04194584eaeeb84576270cc3fc59002ba33bff9639bb0b02
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 NAV1 LYN EDNRB

1.19e-04194584b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCellPND03-Endothelial-Endothelial_blood-vessel|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.19e-04194584f93f5148b136819d87faef89707dbaba07d6c2b5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.21e-04195584d700e959e060932e3854a9cf294799465efbe18b
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC1 DMXL2 IRAK1 LYN

1.21e-041955849d649ac7d2af313481069c95349efc0c68449e2b
ToppCellChildren_(3_yrs)-Immune-monocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DMXL2 PIK3CD NAV1 LYN

1.21e-0419558481a28289eda1a8a1a31b7357106f64ac5000e172
ToppCellfacs-Heart-RA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAMP2 RAPGEF5 APLP2 EDNRB

1.21e-04195584f4fdcc0b851392086e9618e76ee6a0b540d5fb3c
ToppCellControl-Myeloid|Control / Disease state, Lineage and Cell class

FOXO3 MRC1 DMXL2 APLP2

1.21e-0419558446ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCellPND03-Endothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAMP2 RAPGEF5 NAV1 EDNRB

1.23e-04196584a529681d822a95dd1980b7b1c71dc61aaf0baecd
ToppCellMild_COVID-19-Myeloid-MoAM3|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MRC1 IRAK1 APLP2 LYN

1.23e-041965849faad17aa0b6af5a8ec2dadf7d70b9209d658072
ToppCellControl-Myeloid-Macrophage|Control / Disease state, Lineage and Cell class

FOXO3 MRC1 DMXL2 IRAK1

1.23e-04196584e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 PIK3CD LRRK1 LYN

1.23e-04196584291c59b609985167c98a40d4e2caeea2fad74941
ToppCell10x5'-Lung-Myeloid_Mac-Intermediate_macrophages|Lung / Manually curated celltypes from each tissue

DMXL2 IRAK1 APLP2 LYN

1.23e-04196584fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 PIK3CD LRRK1 LYN

1.26e-04197584d95565652ca318a2298d6918d54ba6367e9560f4
ToppCellChildren_(3_yrs)-Immune|Children_(3_yrs) / Lineage, Cell type, age group and donor

MRC1 DMXL2 PIK3CD LYN

1.26e-04197584f18807124b91310fcd84238484a80ecdba684679
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 PIK3CD LRRK1 LYN

1.26e-0419758457dafb3047745a44b2345b8036e159c3641d496e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 PIK3CD LRRK1 LYN

1.26e-04197584826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCellLPS_only-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_only / Treatment groups by lineage, cell group, cell type

MRC1 DMXL2 MAPKAPK3 LYN

1.28e-041985842985c80e656e483866c696fa08c38af90311cd66
ToppCellImmune|World / Lineage, Cell type, age group and donor

MRC1 DMXL2 PIK3CD LYN

1.28e-0419858465681b54d13c6997bd90a1c2a12314a80e964fe3
ToppCellLPS_only-Hematopoietic_Myeloid-Monocytes,_Macrophages|LPS_only / Treatment groups by lineage, cell group, cell type

MRC1 DMXL2 MAPKAPK3 LYN

1.28e-041985845d48539999d7a17f4165f612bf68be26c085e501
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MRC1 DMXL2 KLHL15 APLP2

1.28e-0419858493cc01d91ffc543fd1a717ef47e02e532b50b665
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MRC1 PIK3CD LRRK1 LYN

1.28e-04198584623f9d64c9e800d2d7f623392bf2f22b563f0249
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 FOXL2 USP9Y

1.29e-04755833167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TBX4 FOXL2 USP9Y

1.29e-047558370c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
DiseaseMalignant Granulosa Cell Tumor

FOXL2 DICER1

3.54e-062562C0334401
DiseaseGranulosa Cell Cancer

FOXL2 DICER1

3.52e-055562C1567257
DiseaseHbA1c measurement, polycystic ovary syndrome

FTO ASB15

3.52e-055562EFO_0000660, EFO_0004541
Diseasesmoking behavior, body mass index

FOXO3 DMXL2 NAV1 FTO

8.93e-05123564EFO_0004318, EFO_0004340
DiseaseN-acetylhistidine measurement

IFT22 SLC17A4

1.92e-0411562EFO_0800022
Diseasediffuse scleroderma (is_implicated_in)

IRAK1 TAP1

1.92e-0411562DOID:1580 (is_implicated_in)
Diseasewaist-hip ratio

FOXO3 DMXL2 TBX4 TTC12 SLC17A4 PSMD12 FTO ASB15 ELL

4.67e-041226569EFO_0004343
Diseaseankylosing spondylitis (is_implicated_in)

IRAK1 TAP1

5.93e-0419562DOID:7147 (is_implicated_in)
DiseaseObesity

FOXO3 MRC1 PTPN1 FTO

6.26e-04205564C0028754
Diseasebrain stem volume measurement

FOXO3 PTPN1

9.51e-0424562EFO_0010605
DiseaseEndogenous Hyperinsulinism

MRC1 PTPN1

1.12e-0326562C1257963
DiseaseExogenous Hyperinsulinism

MRC1 PTPN1

1.12e-0326562C1257964
DiseaseCompensatory Hyperinsulinemia

MRC1 PTPN1

1.12e-0326562C1257965
DiseaseHyperinsulinism

MRC1 PTPN1

1.30e-0328562C0020459
DiseaseBilateral Wilms Tumor

DROSHA DICER1

1.39e-0329562C2930471
DiseaseR-warfarin measurement

TDRD3 CYP2R1 ELAPOR1 FTO

1.62e-03265564EFO_0803324
Diseaseintestinal cancer (implicated_via_orthology)

PTPN1 LYN

1.69e-0332562DOID:10155 (implicated_via_orthology)
Diseasepuberty onset measurement

HPGDS FTO ECPAS

1.75e-03125563EFO_0005677

Protein segments in the cluster

PeptideGeneStartEntry
LQDCMYKDVQKDWPG

ELL

261

P55199
YEYSVWDPKKLCMDP

GOT1L1

151

Q8NHS2
SDVMYTDWKKDKCEP

ORM2

171

P19652
KYAMDEADEKGWFPL

ASB15

66

Q8WXK1
KLLAEDWPFGAEMCK

EDNRB

161

P24530
TAGKDDCLLKVWYPM

DMXL2

186

Q8TDJ6
WDAMCYLDPSKAVEE

DICER1

1506

Q9UPY3
YLKQWSKPREDMECD

BAZ1A

391

Q9NRL2
HYKDQMDPIEKDWCD

RAMP2

71

O60895
AVMPRWYFDLSKGKC

APLP2

321

Q06481
DAMGYKPIDFCKIWN

ANKRD53

241

Q8N9V6
CAQYWPQKEEKEMIF

PTPN1

121

P18031
PEKYDKSCDMWSLGV

MAPKAPK3

216

Q16644
ALECLPDKMAVFWKN

LRRK1

436

Q38SD2
ECRPYWEKDDASMPL

FTO

471

Q9C0B1
EKWGFPMCHYLKEER

METTL25

431

Q8N6Q8
MYKWAKPKICSEDLE

ELAPOR1

351

Q6UXG2
DDFMSCFPWAEKKQD

HPGDS

96

O60760
WYMEKEEPIYKTSCA

ECPAS

1446

Q5VYK3
NYWTLDPACEDMFEK

FOXL2

126

P58012
WTMALPEEAKIKDAY

GGA3

121

Q9NZ52
CKEMAPAWEALAEKY

PDIA2

421

Q13087
VKMCYEAKEWDLLNE

PSMD12

71

O00232
YKVMDALEPADWCQF

IRAK1

31

P51617
DMLHDKWYRVVPCGK

GRIN3A

901

Q8TCU5
GDAKFESCWPALMKD

IFT22

66

Q9H7X7
FQKELMCFDPDTDKW

KLHL13

501

Q9P2N7
DENKWKEDEYPRMPC

KLHL15

566

Q96M94
SWDDKCKMPYTEAVL

CYP2R1

351

Q6VVX0
EGLCKWVIAMDSYDK

DNAH7

2791

Q8WXX0
ENCPDELYDIMKMCW

LYN

466

P07948
YMPDVAKCRQWLEKN

DENR

46

O43583
LEKMEWPNHYACEKL

GEN1

361

Q17RS7
EAKLDKPDVVNWMCY

LCAT

61

P04180
KPDVVNWMCYRKTED

LCAT

66

P04180
ETLKEFKAMAPAYDW

SLC17A4

91

Q9Y2C5
WIDIKRMDDPECYFN

KYAT3

326

Q6YP21
DDLGALWACPMDKYI

IL17RC

521

Q8NAC3
FLDKAEDSWPSDMCK

PNLIPRP2

96

P54317
EDCVVMKGKDGYWAD

MRC1

461

P22897
LYEPEWSDDMAKAPK

NAV1

106

Q8NEY1
WMVRCVPYFKDKGDS

FOXO3

186

O43524
ACFKWYSKLMGDEPD

USP9X

696

Q93008
AQKEICKMLSPWYDE

RGSL1

471

A5PLK6
CKMLSPWYDEFLDEE

RGSL1

476

A5PLK6
EELEWQKYAEECKGM

DROSHA

726

Q9NRR4
EYAKMWKPGDECFAL

TDRD3

551

Q9H7E2
LQEWYKKFVMECPSG

GUCA1B

21

Q9UMX6
ALYKDWLPEDEHSKM

RAPGEF5

156

Q92565
EKKGCYWAMVQAPAD

TAP1

731

Q03518
CPIAWANLMLFDYKD

PIK3CD

416

O00329
KVADWLLENAMPEYC

SGMS1

11

Q86VZ5
EACFKWYSKLMGDEP

USP9Y

696

O00507
MKLEDYEKALVDCEW

TTC12

151

Q9H892
PADDHRYKFCDNKWM

TBX4

121

P57082
LMKEYFKEWDPLKDC

TFIP11

431

Q9UBB9
DCPYLWAHMKKYTEI

AGL

501

P35573
PICFKNEMDFWKVDL

KCNF1

106

Q9H3M0
APDAMWEDYEFKCKP

LMF1

431

Q96S06
ECPMTRENYEKLWKL

MXRA5

366

Q9NR99