Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsymporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 MFSD12 SLC17A5 SLC46A3 SLC5A6 SLC23A2

4.45e-08150969GO:0015293
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 ABCA12 ABCB5 SLC5A7 ABCC5 ABCA7 ABCA9 MFSD12 SLC17A5 SLC46A3 SLC5A6 SLC23A2

6.52e-084779614GO:0022804
GeneOntologyMolecularFunctiontransporter activity

SLC17A2 SLC11A2 SLC17A3 ABCA12 ABCB5 SLC5A7 ABCC5 ATP8B1 GRIN2A GRIN2B ABCA7 ABCA9 MFSD12 SLC39A13 CHRND SLC17A5 SLC46A3 SLC22A13 SLC5A6 SERINC3 SLC23A2 VDAC3

1.46e-0712899622GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 ABCA12 ABCB5 SLC5A7 ABCC5 GRIN2A GRIN2B ABCA7 ABCA9 MFSD12 SLC39A13 CHRND SLC17A5 SLC46A3 SLC22A13 SLC5A6 SERINC3 SLC23A2 VDAC3

1.48e-0711809621GO:0022857
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC17A3 ABCC5 GRIN2A GRIN2B MFSD12 SLC17A5 SLC22A13 SLC5A6 SERINC3 SLC23A2

1.47e-062939610GO:0008514
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 SLC17A5 SLC5A6 SLC23A2

1.72e-06119967GO:0015294
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

3.73e-0649965GO:0140359
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

GRIN2A GRIN2B MFSD12 SLC17A5 SLC22A13 SLC5A6 SERINC3 SLC23A2

7.07e-06207968GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

GRIN2A GRIN2B MFSD12 SLC17A5 SLC22A13 SLC5A6 SERINC3 SLC23A2

7.33e-06208968GO:0005342
GeneOntologyMolecularFunctionurate transmembrane transporter activity

SLC17A2 SLC17A3 SLC22A13

8.86e-069963GO:0015143
GeneOntologyMolecularFunctionsalt transmembrane transporter activity

SLC17A2 SLC17A3 SLC22A13

8.86e-069963GO:1901702
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 MFSD12 SLC17A5 SLC46A3 SLC5A6 SLC23A2

1.28e-05296969GO:0015291
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC17A2 SLC17A3 SLC5A7 SLC5A6 SLC23A2

4.44e-0581965GO:0015370
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

SLC17A3 ABCB5 ABCC5

5.76e-0516963GO:0015562
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA7 LRP1

6.84e-053962GO:0030226
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

PRLHR OPN4 HTR2B ROR1 ROR2 CASR GRIN2A GRIN2B TAAR8 GABBR2 ITGAL ABCA7 CHRND ADRA1A PTPRA NRXN1 KIT SORL1

6.99e-0513539618GO:0004888
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 GRIN2A GRIN2B SLC39A13 SLC46A3 SLC5A6 SLC23A2

8.03e-054659610GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 GRIN2A GRIN2B SLC39A13 CHRND SLC17A5 SLC46A3 SLC5A6 SLC23A2

8.06e-056649612GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 GRIN2A GRIN2B SLC39A13 CHRND SLC17A5 SLC46A3 SLC5A6 SLC23A2 VDAC3

1.07e-047939613GO:0015075
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

1.82e-04109965GO:0042626
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 GRIN2A GRIN2B SLC39A13 SLC17A5 SLC46A3 SLC5A6 SLC23A2

2.11e-046279611GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 ABCC5 GRIN2A GRIN2B SLC39A13 SLC17A5 SLC46A3 SLC5A6 SLC23A2

2.76e-047589612GO:0015318
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA12 ATP8B1 ABCA7

3.23e-0428963GO:0140326
GeneOntologyMolecularFunctionamino acid binding

AARS1 CASR GRIN2A GRIN2B

4.24e-0473964GO:0016597
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

4.73e-047962GO:0005234
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC17A3 ABCB5 ABCC5

5.78e-0434963GO:0042910
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC17A2 SLC11A2 SLC17A3 SLC5A7 SLC17A5 SLC5A6 SLC23A2

6.26e-04301967GO:0022853
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B

6.29e-048962GO:0022849
GeneOntologyMolecularFunctioncopper ion transmembrane transporter activity

SLC11A2 SLC46A3

6.29e-048962GO:0005375
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ATP8B1 ABCA7

6.29e-048962GO:0090554
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B

6.29e-048962GO:0004972
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP8B1 ABCA7

8.06e-049962GO:0090556
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

HTR2B TAAR8 ADRA1A

1.01e-0341963GO:0008227
GeneOntologyMolecularFunctionexcitatory extracellular ligand-gated monoatomic ion channel activity

GRIN2A GRIN2B CHRND

1.16e-0343963GO:0005231
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

SLC11A2 SLC39A13 SLC46A3

1.24e-0344963GO:0046915
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA12 ABCB5 ABCC5 MSH2 ATP8B1 ABCA7 ABCA9 MOV10

1.29e-03441968GO:0016887
GeneOntologyMolecularFunctionneurotransmitter receptor activity

HTR2B GRIN2A GRIN2B CHRND

1.38e-03100964GO:0030594
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC17A2 SLC17A3 SLC5A7 SLC5A6 SLC23A2

1.42e-03171965GO:0015081
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC17A2 SLC17A3

1.46e-0312962GO:0005436
GeneOntologyMolecularFunctionclathrin heavy chain binding

GPR107 LRP1

1.46e-0312962GO:0032050
GeneOntologyMolecularFunctionamyloid-beta binding

GRIN2A GRIN2B LRP1 SORL1

1.49e-03102964GO:0001540
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIN2A GRIN2B MFSD12 SERINC3

1.65e-03105964GO:0015171
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

1.69e-03178965GO:0015399
GeneOntologyMolecularFunctionUDP-glucosyltransferase activity

GYS2 UGT8

1.72e-0313962GO:0035251
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA12 ATP8B1 ABCA7

1.90e-0351963GO:0140303
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B

2.00e-0314962GO:0016595
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCB5 ABCC5

2.31e-0315962GO:0008559
GeneOntologyMolecularFunctionglucosidase activity

LCTL GAA

2.31e-0315962GO:0015926
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIN2A GRIN2B CHRND

2.61e-0357963GO:1904315
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 SORL1

2.63e-0316962GO:0005041
GeneOntologyMolecularFunctionfloppase activity

ATP8B1 ABCA7

2.63e-0316962GO:0140328
GeneOntologyMolecularFunctionATP-dependent activity

ABCA12 ABCB5 ACSS1 ABCC5 MSH2 ATP8B1 ABCA7 ABCA9 MOV10

2.79e-03614969GO:0140657
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC17A5 SLC23A2

2.97e-0317962GO:0005402
GeneOntologyMolecularFunctionvoltage-gated monoatomic anion channel activity

SLC17A3 VDAC3

2.97e-0317962GO:0008308
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIN2A GRIN2B

2.97e-0317962GO:0004970
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIN2A GRIN2B CHRND

3.02e-0360963GO:0099529
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC5 MFSD12 SLC5A6

3.17e-0361963GO:1901682
GeneOntologyMolecularFunctionamide binding

PRLHR SRD5A2 GRIN2A GRIN2B LRP1 SORL1

3.22e-03299966GO:0033218
GeneOntologyMolecularFunctionhexosyltransferase activity

GYS2 UGT8 CERCAM GALNT5 FUT2

3.53e-03211965GO:0016758
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIN2A GRIN2B CHRND

3.79e-0365963GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIN2A GRIN2B CHRND

3.79e-0365963GO:0022824
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

ROR1 ROR2 KIT

3.79e-0365963GO:0004714
GeneOntologyMolecularFunctionphosphatidylcholine transporter activity

ATP8B1 ABCA7

4.11e-0320962GO:0008525
GeneOntologyMolecularFunctionpeptide binding

PRLHR GRIN2A GRIN2B LRP1 CTSD SORL1

4.35e-03318966GO:0042277
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 SORL1

4.53e-0321962GO:0030228
GeneOntologyMolecularFunctionmicrotubule plus-end binding

CLIP4 TBCB

4.96e-0322962GO:0051010
GeneOntologyMolecularFunctionglucosyltransferase activity

GYS2 UGT8

4.96e-0322962GO:0046527
GeneOntologyMolecularFunctioncoreceptor activity

ROR1 ROR2 LRP1

5.05e-0372963GO:0015026
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

MATK ROR1 ROR2 KIT

5.29e-03145964GO:0004713
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIN2A GRIN2B CHRND

5.66e-0375963GO:0098960
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC17A2 SLC17A3

5.89e-0324962GO:0005315
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIN2A GRIN2B

5.89e-0324962GO:0099507
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIN2A GRIN2B CHRND

6.09e-0377963GO:0005230
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

GYS2 UGT8 CERCAM GALNT5

6.38e-03153964GO:0008194
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC11A2 SLC17A5

6.39e-0325962GO:0015295
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN2A GRIN2B

7.42e-0327962GO:0008066
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC5A7 MFSD12 SERINC3

7.50e-0383963GO:0015101
GeneOntologyMolecularFunctioncargo receptor activity

ABCA7 LRP1 SORL1

8.00e-0385963GO:0038024
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

ROR1 ROR2 KIT

8.00e-0385963GO:0019199
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC17A2 SLC17A3 ABCC5 SLC5A6

9.37e-03171964GO:0015103
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC17A2 SLC17A3 ABCC5 CASR ATP8B1 SLC17A5 SLC5A6 VDAC3

2.25e-06183968GO:0006820
GeneOntologyBiologicalProcessorganic anion transport

SLC17A2 SLC17A3 ABCC5 CASR ATP8B1 GRIN2B MFSD12 SLC17A5 SLC22A13 SLC5A6 SERINC3 SLC23A2

4.81e-065159612GO:0015711
GeneOntologyBiologicalProcesspositive regulation of inhibitory postsynaptic potential

GRIN2A GRIN2B IGSF9B

1.15e-0510963GO:0097151
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC17A2 SLC11A2 HTR2B SLC17A3 ABCC5 CASR ATP8B1 GRIN2A GRIN2B SLC39A13 CHRND SLC17A5 ADRA1A SLC46A3 SLC5A6 SLC23A2 VDAC3

1.38e-0511159617GO:0034220
GeneOntologyBiologicalProcessurate transport

SLC17A2 SLC17A3 SLC22A13

1.57e-0511963GO:0015747
GeneOntologyBiologicalProcesspositive regulation of ERK1 and ERK2 cascade

HTR2B ROR1 ROR2 CASR ABCA7 ADRA1A NRXN1 LRP1

1.64e-05240968GO:0070374
GeneOntologyBiologicalProcessmodulation of inhibitory postsynaptic potential

GRIN2A GRIN2B IGSF9B

2.09e-0512963GO:0098828
GeneOntologyBiologicalProcesscarboxylic acid transport

ABCC5 CASR ATP8B1 GRIN2B MFSD12 SLC17A5 SLC22A13 SLC5A6 SERINC3 SLC23A2

2.13e-054109610GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

ABCC5 CASR ATP8B1 GRIN2B MFSD12 SLC17A5 SLC22A13 SLC5A6 SERINC3 SLC23A2

2.22e-054129610GO:0015849
GeneOntologyBiologicalProcesspositive regulation of synaptic transmission, glutamatergic

ROR2 GRIN2A GRIN2B NRXN1

4.73e-0543964GO:0051968
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC17A2 SLC11A2 HTR2B SLC17A3 SLC5A7 ABCC5 CASR ATP8B1 GRIN2A GRIN2B SLC39A13 CHRND SLC17A5 ADRA1A SLC46A3 SLC5A6 SLC23A2 VDAC3

5.62e-0513749618GO:0006811
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

ROR2 GRIN2A GRIN2B NRXN1 FRRS1L

7.02e-0592965GO:0051966
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

SLC11A2 HTR2B PILRB ROR1 ROR2 MSH2 GRIN2A GRIN2B KHDC1 ADRA1A NRXN1 SPDYE3 CTSD KIT VAV1

7.77e-0510289615GO:0043085
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC17A2 SLC11A2 HTR2B SLC17A3 SLC5A7 ABCC5 CASR GRIN2A GRIN2B SLC39A13 CHRND SLC17A5 ADRA1A SLC46A3 SLC5A6 SLC23A2

8.23e-0511579616GO:0006812
GeneOntologyBiologicalProcessneuromuscular process

AARS1 CNTNAP1 GRIN2A GRIN2B CHRND NRXN1 GAA

8.76e-05225967GO:0050905
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

HTR2B ROR2 SLC5A7 GRIN2A GRIN2B GABBR2 CHRND ADRA1A PTPRA NRXN1 FRRS1L IGSF9B KIT VDAC3

1.01e-049319614GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

HTR2B ROR2 SLC5A7 GRIN2A GRIN2B GABBR2 CHRND ADRA1A PTPRA NRXN1 FRRS1L IGSF9B KIT VDAC3

1.01e-049319614GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

HTR2B ROR2 SLC5A7 GRIN2A GRIN2B GABBR2 CHRND ADRA1A PTPRA NRXN1 FRRS1L IGSF9B KIT VDAC3

1.10e-049399614GO:0099537
GeneOntologyBiologicalProcessamide metabolic process

ABCA12 TECR ACSS1 ABCA7 SLC5A6 CLN6 UGT8 CORIN CHAC1 SORL1

1.34e-045119610GO:0043603
GeneOntologyBiologicalProcessvitamin transmembrane transport

ABCC5 SLC5A6 SLC23A2

1.62e-0423963GO:0035461
GeneOntologyBiologicalProcesssynaptic signaling

HTR2B ROR2 SLC5A7 GRIN2A GRIN2B GABBR2 CHRND ADRA1A PTPRA NRXN1 FRRS1L IGSF9B KIT VDAC3

1.65e-049769614GO:0099536
GeneOntologyBiologicalProcesssphingolipid metabolic process

ABCA12 TECR CLN6 UGT8 FUT2 KIT

1.74e-04176966GO:0006665
GeneOntologyBiologicalProcessmetal ion transport

SLC17A2 SLC11A2 HTR2B SLC17A3 SLC5A7 ABCC5 CASR GRIN2A GRIN2B SLC39A13 ADRA1A SLC46A3 SLC5A6 SLC23A2

2.12e-0410009614GO:0030001
GeneOntologyBiologicalProcessneuron-glial cell signaling

GABBR2 ADRA1A

2.12e-045962GO:0150099
GeneOntologyBiologicalProcessinsulin receptor recycling

CTSD SORL1

2.12e-045962GO:0038020
GeneOntologyBiologicalProcessprotein localization to paranode region of axon

CNTNAP1 UGT8

2.12e-045962GO:0002175
GeneOntologyBiologicalProcessxenobiotic transport

SLC17A3 ABCB5 ABCC5 ATP8B1

2.26e-0464964GO:0042908
GeneOntologyBiologicalProcessbehavior

PRLHR OPN4 SLC11A2 HTR2B CASR GRIN2A GRIN2B ABCA7 NRXN1 CLN6 KIT GAA VDAC3

2.44e-048919613GO:0007610
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC17A2 SLC11A2 HTR2B SLC17A3 ABCC5 CASR GRIN2A GRIN2B SLC39A13 SLC17A5 ADRA1A SLC46A3 SLC5A6 SLC23A2

2.52e-0410179614GO:0098660
GeneOntologyBiologicalProcesspositive regulation of cholesterol efflux

ABCA12 ABCA7 LRP1

2.64e-0427963GO:0010875
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

GRIN2A GRIN2B IGSF9B

2.64e-0427963GO:0060080
GeneOntologyBiologicalProcesspositive regulation of molecular function

SLC11A2 HTR2B PILRB ROR1 ROR2 CASR MSH2 GRIN2A GRIN2B KHDC1 ADRA1A NRXN1 SPDYE3 LRP1 CTSD KIT VAV1

2.98e-0414309617GO:0044093
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC17A2 SLC11A2 HTR2B SLC17A3 ABCC5 GRIN2A GRIN2B SLC39A13 SLC17A5 ADRA1A SLC46A3 SLC5A6 SLC23A2

3.40e-049229613GO:0098662
GeneOntologyBiologicalProcessglycosphingolipid metabolic process

CLN6 UGT8 FUT2 KIT

3.75e-0473964GO:0006687
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

ROR2 GRIN2A GRIN2B NRXN1 FRRS1L

3.82e-04132965GO:0035249
GeneOntologyBiologicalProcessneuromuscular process controlling balance

AARS1 CNTNAP1 NRXN1 GAA

3.95e-0474964GO:0050885
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC17A2 SLC11A2 HTR2B SLC17A3 ABCC5 GRIN2A GRIN2B SLC39A13 SLC17A5 ADRA1A SLC46A3 SLC5A6 SLC23A2

4.17e-049429613GO:0098655
GeneOntologyBiologicalProcessprotein localization to membrane

EMC6 ABCA12 GRIN2A GRIN2B ITGAL NRXN1 FRRS1L TMEM147 LRP1 HECTD1 SORL1

4.34e-047059611GO:0072657
GeneOntologyBiologicalProcessregulation of ERK1 and ERK2 cascade

HTR2B ROR1 ROR2 CASR ABCA7 ADRA1A NRXN1 LRP1

4.35e-04385968GO:0070372
GeneOntologyBiologicalProcesslearning

GRIN2A GRIN2B ABCA7 NRXN1 KIT VDAC3

4.72e-04212966GO:0007612
GeneOntologyBiologicalProcessreceptor metabolic process

GRIN2A PIK3R4 CTSD SORL1

5.84e-0482964GO:0043112
GeneOntologyBiologicalProcesspositive regulation of amyloid-beta clearance

ABCA7 LRP1

5.89e-048962GO:1900223
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

ABCA7 LRP1

5.89e-048962GO:0150094
GeneOntologyBiologicalProcessparanodal junction assembly

CNTNAP1 UGT8

5.89e-048962GO:0030913
GeneOntologyBiologicalProcesspositive regulation of kinase activity

HTR2B PILRB ROR1 ROR2 ADRA1A NRXN1 SPDYE3 KIT

6.07e-04405968GO:0033674
GeneOntologyBiologicalProcessreceptor clustering

GRIN2B ITGAL NRXN1 FRRS1L

6.11e-0483964GO:0043113
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

GRIN2A GRIN2B CHRND NRXN1 IGSF9B

6.24e-04147965GO:0099565
GeneOntologyBiologicalProcessvisual behavior

OPN4 GRIN2A ABCA7 KIT

6.99e-0486964GO:0007632
GeneOntologyBiologicalProcessmembrane lipid metabolic process

ABCA12 TECR CLN6 UGT8 FUT2 KIT

7.08e-04229966GO:0006643
GeneOntologyBiologicalProcesspositive regulation of cysteine-type endopeptidase activity

SLC11A2 GRIN2A GRIN2B KHDC1 CTSD

7.26e-04152965GO:2001056
GeneOntologyBiologicalProcessERK1 and ERK2 cascade

HTR2B ROR1 ROR2 CASR ABCA7 ADRA1A NRXN1 LRP1

7.45e-04418968GO:0070371
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC17A3 ABCC5 CASR SLC5A6 VDAC3

7.47e-04153965GO:0098656
GeneOntologyBiologicalProcesscopper ion transmembrane transport

SLC11A2 SLC46A3

7.56e-049962GO:0035434
GeneOntologyBiologicalProcessregulation of long-term neuronal synaptic plasticity

GRIN2A GRIN2B KIT

8.52e-0440963GO:0048169
GeneOntologyBiologicalProcesspositive regulation of sterol transport

ABCA12 ABCA7 LRP1

8.52e-0440963GO:0032373
GeneOntologyBiologicalProcesspositive regulation of cholesterol transport

ABCA12 ABCA7 LRP1

8.52e-0440963GO:0032376
GeneOntologyBiologicalProcessstartle response

GRIN2A GRIN2B NRXN1

9.16e-0441963GO:0001964
GeneOntologyBiologicalProcessintestine smooth muscle contraction

HTR2B KIT

9.42e-0410962GO:0014827
GeneOntologyBiologicalProcessorganophosphate ester transport

SLC17A3 ABCA12 ABCC5 ATP8B1 ABCA7

9.66e-04162965GO:0015748
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

ABCC5 MFSD12 SLC17A5 SLC5A6 SLC23A2

9.93e-04163965GO:1905039
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

GRIN2A GRIN2B NRXN1

1.05e-0343963GO:2000463
GeneOntologyBiologicalProcessorganic acid transmembrane transport

ABCC5 MFSD12 SLC17A5 SLC5A6 SLC23A2

1.11e-03167965GO:1903825
GeneOntologyBiologicalProcessprotein localization to axon

CNTNAP1 UGT8

1.15e-0311962GO:0099612
GeneOntologyBiologicalProcessregulation of membrane potential

ABCB5 CNTNAP1 CASR GRIN2A GRIN2B CHRND ADRA1A NRXN1 IGSF9B

1.18e-03559969GO:0042391
GeneOntologyBiologicalProcesslocalization within membrane

EMC6 ABCA12 GRIN2A GRIN2B ITGAL NRXN1 FRRS1L TMEM147 LRP1 HECTD1 SORL1

1.20e-037989611GO:0051668
GeneOntologyCellularComponentpresynapse

ROR1 CNTNAP1 SLC5A7 DAO CASR GRIN2A GRIN2B GABBR2 SLC17A5 ADRA1A NRXN1 LGI3 EGFLAM CTSD VDAC3

1.37e-058869715GO:0098793
GeneOntologyCellularComponentreceptor complex

HTR2B ROR1 ROR2 GRIN2A GRIN2B GABBR2 ITGAL CHRND PTPRA LRP1 ALCAM KIT

1.57e-055819712GO:0043235
GeneOntologyCellularComponentapical plasma membrane

SLC17A2 SLC11A2 SLC17A3 SLC5A7 ABCC5 CASR ATP8B1 ABCA7 SLC22A13 SLC5A6 SLC23A2

1.60e-054879711GO:0016324
GeneOntologyCellularComponentapical part of cell

SLC17A2 SLC11A2 SLC17A3 SLC5A7 ABCC5 CASR ATP8B1 ABCA7 SLC22A13 SLC5A6 LRP1 SLC23A2

1.90e-055929712GO:0045177
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SLC11A2 ABCA12 ROR2 SLC5A7 ABCC5 GRIN2A GRIN2B ITGAL ABCA7 MFSD12 SLC39A13 PIK3R4 SLC17A5 LRP1 CTSD GAA SORL1

9.88e-0513079717GO:0030659
GeneOntologyCellularComponentvesicle membrane

SLC11A2 ABCA12 ROR2 SLC5A7 ABCC5 GRIN2A GRIN2B ITGAL ABCA7 MFSD12 SLC39A13 PIK3R4 SLC17A5 LRP1 CTSD GAA SORL1

1.17e-0413259717GO:0012506
GeneOntologyCellularComponentneuronal cell body

OPN4 HTR2B ROR2 SRD5A2 SLC5A7 CASR GRIN2B NRXN1 LRP1 ASTN2 IGSF9B ALCAM SORL1

1.26e-048359713GO:0043025
GeneOntologyCellularComponentaxon

OPN4 ROR1 CNTNAP1 SLC5A7 CASR GRIN2A GRIN2B CLDN11 NRXN1 LGI3 LRP1 IGSF9 ALCAM

2.38e-048919713GO:0030424
GeneOntologyCellularComponentcell body

OPN4 HTR2B ROR2 SRD5A2 SLC5A7 CASR GRIN2B NRXN1 LRP1 ASTN2 IGSF9B ALCAM SORL1

3.56e-049299713GO:0044297
GeneOntologyCellularComponentsynaptic membrane

SLC5A7 GRIN2A GRIN2B GABBR2 CHRND ADRA1A PTPRA NRXN1 LRP1 IGSF9B

3.76e-045839710GO:0097060
GeneOntologyCellularComponentbasal part of cell

SLC11A2 ABCC5 CASR SLC17A5 CLDN11 SLC5A6 LRP1 SLC23A2

3.78e-04378978GO:0045178
GeneOntologyCellularComponentinhibitory synapse

NRXN1 IGSF9 IGSF9B

3.96e-0431973GO:0060077
GeneOntologyCellularComponentpresynaptic active zone

CNTNAP1 DAO GRIN2B NRXN1 EGFLAM

5.10e-04141975GO:0048786
GeneOntologyCellularComponentsomatodendritic compartment

OPN4 HTR2B ROR2 SRD5A2 SLC5A7 CASR GRIN2A GRIN2B NRXN1 LRP1 ASTN2 IGSF9 IGSF9B ALCAM SORL1

5.18e-0412289715GO:0036477
GeneOntologyCellularComponentcell surface

SLC11A2 ROR1 ROR2 CASR GRIN2A GRIN2B ITGAL ABCA7 NRXN1 LRP1 CORIN ALCAM KIT SORL1

5.96e-0411119714GO:0009986
GeneOntologyCellularComponentbrush border membrane

SLC11A2 SLC17A3 ATP8B1 SLC5A6

6.05e-0483974GO:0031526
GeneOntologyCellularComponentbrush border

SLC11A2 SLC17A3 ATP8B1 LCTL SLC5A6

7.16e-04152975GO:0005903
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B

7.51e-049972GO:0017146
GeneOntologyCellularComponentendoplasmic reticulum membrane

EMC6 SLC17A3 TECR SRD5A2 MMP23B GRIN2A GRIN2B SLC39A13 LCTL FRRS1L TMEM147 CLN6 UGT8 FITM1 SORL1

8.81e-0412939715GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

EMC6 SLC17A3 TECR SRD5A2 MMP23B GRIN2A GRIN2B SLC39A13 LCTL FRRS1L TMEM147 CLN6 UGT8 FITM1 SORL1

9.23e-0412999715GO:0098827
GeneOntologyCellularComponentendosome

SLC11A2 SLC5A7 ABCC5 GRIN2B BIRC6 ABCA7 MFSD12 GPR107 PIK3R4 LRP1 CLN6 ASTN2 CTSD SORL1

9.63e-0411679714GO:0005768
GeneOntologyCellularComponentGABA-ergic synapse

GABBR2 ADRA1A NRXN1 IGSF9B CTSD

1.01e-03164975GO:0098982
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

EMC6 SLC17A3 TECR SRD5A2 MMP23B GRIN2A GRIN2B SLC39A13 LCTL FRRS1L TMEM147 CLN6 UGT8 FITM1 SORL1

1.14e-0313279715GO:0042175
GeneOntologyCellularComponentearly endosome

SLC11A2 SLC5A7 ABCA7 GPR107 LRP1 CLN6 ASTN2 SORL1

1.79e-03481978GO:0005769
GeneOntologyCellularComponentpresynaptic membrane

SLC5A7 GRIN2A GRIN2B GABBR2 ADRA1A NRXN1

1.85e-03277976GO:0042734
GeneOntologyCellularComponentsynaptic vesicle

SLC5A7 GRIN2A GRIN2B SLC17A5 LGI3 VDAC3

2.76e-03300976GO:0008021
GeneOntologyCellularComponentpostsynaptic membrane

GRIN2A GRIN2B GABBR2 CHRND ADRA1A LRP1 IGSF9B

2.80e-03405977GO:0045211
GeneOntologyCellularComponenttransport vesicle

ABCA12 SLC5A7 GRIN2A GRIN2B SLC17A5 LGI3 VDAC3 SORL1

2.87e-03519978GO:0030133
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC5 CASR SLC17A5 SLC5A6 LRP1 SLC23A2

3.78e-03320976GO:0016323
GeneOntologyCellularComponentexocytic vesicle

SLC5A7 GRIN2A GRIN2B SLC17A5 LGI3 VDAC3

3.78e-03320976GO:0070382
GeneOntologyCellularComponentcluster of actin-based cell projections

SLC11A2 SLC17A3 ATP8B1 LCTL SLC5A6

3.85e-03223975GO:0098862
GeneOntologyCellularComponentglutamatergic synapse

ROR2 CNTNAP1 CASR GRIN2A GRIN2B GABBR2 SLC17A5 ADRA1A NRXN1 LRP1

4.62e-038179710GO:0098978
GeneOntologyCellularComponentclathrin-coated vesicle

ROR2 SLC5A7 GPR107 LRP1 ASTN2

4.97e-03237975GO:0030136
GeneOntologyCellularComponentlate endosome

SLC11A2 GRIN2B MFSD12 PIK3R4 ASTN2 SORL1

5.67e-03348976GO:0005770
GeneOntologyCellularComponentlysosomal membrane

SLC11A2 MFSD12 SLC17A5 SLC46A3 LRP1 CTSD GAA

5.74e-03462977GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

SLC11A2 MFSD12 SLC17A5 SLC46A3 LRP1 CTSD GAA

5.74e-03462977GO:0098852
GeneOntologyCellularComponentplasma membrane signaling receptor complex

GRIN2A GRIN2B GABBR2 ITGAL CHRND ALCAM

5.82e-03350976GO:0098802
GeneOntologyCellularComponentbasal plasma membrane

ABCC5 CASR SLC17A5 SLC5A6 LRP1 SLC23A2

6.15e-03354976GO:0009925
GeneOntologyCellularComponentdendrite

OPN4 HTR2B ROR2 SLC5A7 GRIN2A GRIN2B LRP1 IGSF9 IGSF9B ALCAM

6.46e-038589710GO:0030425
GeneOntologyCellularComponentdendritic tree

OPN4 HTR2B ROR2 SLC5A7 GRIN2A GRIN2B LRP1 IGSF9 IGSF9B ALCAM

6.57e-038609710GO:0097447
DomainMFS_1

SLC17A2 SLC17A3 MFSD12 SLC17A5 SLC46A3 SLC22A13

2.46e-0677946PF07690
DomainMFS

SLC17A2 SLC17A3 MFSD12 SLC17A5 SLC46A3 SLC22A13

2.46e-0677946IPR011701
DomainABC_tran

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

4.19e-0648945PF00005
DomainABC_TRANSPORTER_2

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

4.19e-0648945PS50893
DomainABC_TRANSPORTER_1

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

4.64e-0649945PS00211
DomainABC_transporter-like

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

5.14e-0650945IPR003439
DomainMFS

SLC17A2 SLC17A3 MFSD12 SLC17A5 SLC46A3 SLC22A13

1.75e-05108946PS50850
DomainTyr_kinase_rcpt_ROR

ROR1 ROR2

2.51e-052942IPR016247
DomainABC_A

ABCA12 ABCA7 ABCA9

2.63e-0512943IPR026082
DomainANF_lig-bd_rcpt

CASR GRIN2A GRIN2B GABBR2

3.50e-0537944IPR001828
DomainANF_receptor

CASR GRIN2A GRIN2B GABBR2

3.50e-0537944PF01094
DomainPeripla_BP_I

CASR GRIN2A GRIN2B GABBR2

4.32e-0539944IPR028082
DomainABC_transporter_CS

ABCA12 ABCB5 ABCC5 ABCA7

5.82e-0542944IPR017871
DomainMFS_dom

SLC17A2 SLC17A3 MFSD12 SLC17A5 SLC46A3 SLC22A13

5.92e-05134946IPR020846
DomainNMDAR2_C

GRIN2A GRIN2B

7.49e-053942PF10565
DomainNMDAR2_C

GRIN2A GRIN2B

7.49e-053942IPR018884
Domain-

PILRB PILRA ROR1 ROR2 MMP23B ASTN2 IGSF9 EGFLAM IGSF9B ALCAM KIT SORL1

1.21e-0466394122.60.40.10
DomainIg-like_fold

PILRB PILRA ROR1 ROR2 MMP23B ASTN2 IGSF9 EGFLAM IGSF9B ALCAM KIT SORL1

2.17e-047069412IPR013783
DomainFrizzled_dom

ROR1 ROR2 CORIN

2.31e-0424943IPR020067
DomainFZ

ROR1 ROR2 CORIN

2.31e-0424943PS50038
DomainFz

ROR1 ROR2 CORIN

2.31e-0424943PF01392
Domain3-oxo-5_a-steroid_4-DH_C

TECR SRD5A2

2.48e-045942IPR001104
DomainSteroid_dh

TECR SRD5A2

2.48e-045942PF02544
DomainTDE1/TMS

SERINC2 SERINC3

2.48e-045942IPR005016
DomainS5A_REDUCTASE

TECR SRD5A2

2.48e-045942PS50244
DomainSerinc

SERINC2 SERINC3

2.48e-045942PF03348
Domain7TM_GPCR_Srsx

PRLHR OPN4 HTR2B TAAR8 ADRA1A

2.55e-04112945SM01381
DomainIG

PILRB PILRA ROR1 ROR2 MMP23B IGSF9 IGSF9B ALCAM KIT

2.70e-04421949SM00409
DomainIg_sub

PILRB PILRA ROR1 ROR2 MMP23B IGSF9 IGSF9B ALCAM KIT

2.70e-04421949IPR003599
DomainAAA+_ATPase

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

8.04e-04144945IPR003593
DomainAAA

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

8.04e-04144945SM00382
DomainIG_LIKE

PILRB PILRA ROR1 ROR2 MMP23B IGSF9 IGSF9B ALCAM KIT

8.20e-04491949PS50835
DomainLAM_G_DOMAIN

CNTNAP1 NRXN1 EGFLAM

9.17e-0438943PS50025
DomainIg-like_dom

PILRB PILRA ROR1 ROR2 MMP23B IGSF9 IGSF9B ALCAM KIT

9.72e-04503949IPR007110
DomainTyrKc

MATK ROR1 ROR2 KIT

1.02e-0388944SM00219
DomainTyr_kinase_cat_dom

MATK ROR1 ROR2 KIT

1.02e-0388944IPR020635
DomainLDLR_class-A_CS

LRP1 CORIN SORL1

1.07e-0340943IPR023415
DomainLaminin_G_2

CNTNAP1 NRXN1 EGFLAM

1.07e-0340943PF02210
DomainCAP_GLY

CLIP4 TBCB

1.10e-0310942PF01302
DomainCAP_GLY_1

CLIP4 TBCB

1.10e-0310942PS00845
DomainCAP_GLY_2

CLIP4 TBCB

1.10e-0310942PS50245
DomainCAP-Gly_domain

CLIP4 TBCB

1.10e-0310942IPR000938
DomainCAP_GLY

CLIP4 TBCB

1.10e-0310942SM01052
Domain-

CLIP4 TBCB

1.10e-03109422.30.30.190
DomainIGc2

ROR1 ROR2 IGSF9 IGSF9B ALCAM KIT

1.21e-03235946SM00408
DomainEGF_3

CNTNAP1 NRXN1 LRP1 ASTN2 EGFLAM SORL1

1.21e-03235946PS50026
DomainIg_sub2

ROR1 ROR2 IGSF9 IGSF9B ALCAM KIT

1.21e-03235946IPR003598
DomainNA_SOLUT_SYMP_1

SLC5A7 SLC5A6

1.34e-0311942PS00456
DomainLamG

CNTNAP1 NRXN1 EGFLAM

1.41e-0344943SM00282
DomainPROTEIN_KINASE_TYR

MATK ROR1 ROR2 KIT

1.46e-0397944PS00109
DomainTyr_kinase_AS

MATK ROR1 ROR2 KIT

1.46e-0397944IPR008266
DomainLdl_recept_a

LRP1 CORIN SORL1

1.50e-0345943PF00057
DomainNA_SOLUT_SYMP_2

SLC5A7 SLC5A6

1.60e-0312942PS00457
DomainSSF

SLC5A7 SLC5A6

1.60e-0312942PF00474
DomainNa/solute_symporter

SLC5A7 SLC5A6

1.60e-0312942IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A7 SLC5A6

1.60e-0312942PS50283
DomainQuinoprot_gluc/sorb_DH

LGI3 LRP1

1.60e-0312942IPR011041
Domain-

LRP1 CORIN SORL1

1.60e-03469434.10.400.10
Domain6-blade_b-propeller_TolB-like

LGI3 LRP1 SORL1

1.60e-0346943IPR011042
DomainLDLRA_1

LRP1 CORIN SORL1

1.81e-0348943PS01209
DomainLDLRA_2

LRP1 CORIN SORL1

1.92e-0349943PS50068
DomainLDrepeatLR_classA_rpt

LRP1 CORIN SORL1

1.92e-0349943IPR002172
DomainLDLa

LRP1 CORIN SORL1

1.92e-0349943SM00192
DomainLdl_recept_b

LRP1 SORL1

2.19e-0314942PF00058
DomainLDLRB

LRP1 SORL1

2.19e-0314942PS51120
DomainGPCR_3_CS

CASR GABBR2

2.19e-0314942IPR017979
DomainNeurexin-like

CNTNAP1 NRXN1

2.19e-0314942IPR003585
Domain4.1m

CNTNAP1 NRXN1

2.19e-0314942SM00294
DomainEGF_2

CNTNAP1 NRXN1 LRP1 ASTN2 EGFLAM SORL1

2.21e-03265946PS01186
DomainFN3

ASTN2 IGSF9 EGFLAM IGSF9B SORL1

2.43e-03185945SM00060
DomainLY

LRP1 SORL1

2.52e-0315942SM00135
DomainLDLR_classB_rpt

LRP1 SORL1

2.52e-0315942IPR000033
DomainLaminin_G

CNTNAP1 NRXN1 EGFLAM

3.12e-0358943IPR001791
DomainKringle

ROR1 ROR2

3.24e-0317942IPR000001
DomainGal_mutarotase_SF_dom

LGI3 GAA

3.24e-0317942IPR011013
DomainKringle_CS

ROR1 ROR2

3.24e-0317942IPR018056
DomainKRINGLE_2

ROR1 ROR2

3.24e-0317942PS50070
DomainKringle

ROR1 ROR2

3.24e-0317942PF00051
DomainKRINGLE_1

ROR1 ROR2

3.24e-0317942PS00021
DomainKR

ROR1 ROR2

3.24e-0317942SM00130
DomainFN3

ASTN2 IGSF9 EGFLAM IGSF9B SORL1

3.33e-03199945PS50853
DomainIontro_rcpt

GRIN2A GRIN2B

3.64e-0318942IPR001320
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

3.64e-0318942PF10613
DomainIono_rcpt_met

GRIN2A GRIN2B

3.64e-0318942IPR001508
DomainGlu/Gly-bd

GRIN2A GRIN2B

3.64e-0318942IPR019594
DomainLig_chan-Glu_bd

GRIN2A GRIN2B

3.64e-0318942SM00918
DomainLig_chan

GRIN2A GRIN2B

3.64e-0318942PF00060
DomainPBPe

GRIN2A GRIN2B

3.64e-0318942SM00079
DomainEGF

CNTNAP1 NRXN1 LRP1 EGFLAM

3.77e-03126944PF00008
DomainPkinase_Tyr

MATK ROR1 ROR2 KIT

4.10e-03129944PF07714
DomainFN3_dom

ASTN2 IGSF9 EGFLAM IGSF9B SORL1

4.10e-03209945IPR003961
DomainGPCR_3

CASR GABBR2

4.95e-0321942IPR000337
PathwayKEGG_ABC_TRANSPORTERS

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

3.01e-0644735M11911
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B VDAC3

5.80e-0515733M47691
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

PRLHR HTR2B GRIN2A GRIN2B TAAR8 GABBR2 CHRND ADRA1A

7.87e-05272738M13380
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA12 ABCA7 ABCA9

8.60e-0517733MM14552
PathwayWP_NRXN1_DELETION_SYNDROME

GRIN2A GRIN2B NRXN1

1.03e-0418733M48098
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B VDAC3

1.03e-0418733M47761
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA12 ABCA7 ABCA9

1.03e-0418733M524
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B VDAC3

1.22e-0419733M47677
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

1.59e-0499735MM14986
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA12 ABCB5 ABCC5 ABCA7 ABCA9

1.91e-04103735M758
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

2.62e-045732M47667
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC11A2 SLC17A3 ABCA12 ABCB5 SLC5A7 ABCC5 ATP8B1 ABCA7 ABCA9 SLC17A5 SLC5A6 VDAC3

3.66e-047367312M27287
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

3.91e-046732M47668
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

HTR2B CNTNAP1 GRIN2A GRIN2B PIK3R4 ADRA1A NRXN1 KIT

6.01e-04367738M48346
PathwayKEGG_CELL_ADHESION_MOLECULES_CAMS

CNTNAP1 ITGAL CLDN11 NRXN1 ALCAM

6.23e-04133735M16476
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

GRIN2A GRIN2B NRXN1

6.50e-0433733M39875
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC11A2 SLC17A3 ABCA12 ABCB5 SLC5A7 ABCC5 ATP8B1 ABCA7 ABCA9 SLC17A5 SLC5A6

7.12e-046817311MM14985
PathwayREACTOME_SERINE_BIOSYNTHESIS

SERINC2 SERINC3

9.30e-049732M27959
PathwayREACTOME_SERINE_BIOSYNTHESIS

SERINC2 SERINC3

9.30e-049732MM15707
Pubmed

Negative regulation of DSS-induced experimental colitis by PILRα.

PILRB PILRA KIT

2.10e-08397325710489
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

HTR2B CNTNAP1 GRIN2A GRIN2B GABBR2 CHRND ADRA1A NRXN1 ASTN2

1.73e-0730097919086053
Pubmed

Reduced NMDA receptor tyrosine phosphorylation in PTPalpha-deficient mouse synaptosomes is accompanied by inhibition of four src family kinases and Pyk2: an upstream role for PTPalpha in NMDA receptor regulation.

GRIN2A GRIN2B PTPRA

2.09e-07597316899073
Pubmed

Retention of NMDA receptor NR2 subunits in the lumen of endoplasmic reticulum in targeted NR1 knockout mice.

GRIN2A GRIN2B CTSD

2.09e-07597312676993
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

EMC6 NEMP1 ROR2 CNTNAP1 ABCA7 SLC39A13 GPR107 SLC5A6 LRP1 CLN6 UGT8 CERCAM ALCAM CTSD HECTD1 SORL1

2.12e-071201971635696571
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA12 ABCB5 ABCC5 ABCA9

4.00e-07229748894702
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

HTR2B CNTNAP1 GABBR2 ABCA7 MFSD12 SLC39A13 ADRA1A PTPRA SLC5A6 UGT8 SERINC3 ASTN2

5.76e-07697971228298427
Pubmed

Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures.

GRIN2A GRIN2B LRP1

7.30e-07797323267846
Pubmed

Human immunodeficiency virus protein Tat induces synapse loss via a reversible process that is distinct from cell death.

GRIN2A GRIN2B LRP1

7.30e-07797319036954
Pubmed

Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.

GRIN2A GRIN2B LRP1

7.30e-07797323760271
Pubmed

HIV-tat induces formation of an LRP-PSD-95- NMDAR-nNOS complex that promotes apoptosis in neurons and astrocytes.

GRIN2A GRIN2B LRP1

1.17e-06897317360663
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AARS1 CNTNAP1 HECTD4 ABCC5 GRIN2B HNRNPUL1 CLIP4 PIK3R4 PTPRA RSPH1 LGI3 LRP1 CERCAM ASTN2 HECTD1

2.72e-061285971535914814
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

ASTN2 IGSF9 IGSF9B ALCAM KIT

5.85e-069197528558017
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

TECR LRP1 UGT8 CERCAM CTSD SORL1

6.95e-0616497632409323
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

7.70e-06297225131300
Pubmed

ROR1 and ROR2 expression in pancreatic cancer.

ROR1 ROR2

7.70e-06297234763666
Pubmed

Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse.

ITGAL VAV1

7.70e-06297212616499
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

7.70e-06297220921396
Pubmed

Linkage of shambling with sex in linkage group VII of the mouse.

CNTNAP1 KIT

7.70e-0629725661165
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

7.70e-06297227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

7.70e-06297216901514
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

7.70e-06297220696923
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

7.70e-06297223618906
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

7.70e-06297219474217
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

7.70e-06297226179233
Pubmed

Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth.

LRP1 CTSD

7.70e-06297220826454
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

7.70e-06297216033900
Pubmed

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

GRIN2A GRIN2B

7.70e-06297238214768
Pubmed

[Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis].

GRIN2A GRIN2B

7.70e-06297221503117
Pubmed

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.

GRIN2A GRIN2B

7.70e-06297218372311
Pubmed

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors.

GRIN2A GRIN2B

7.70e-06297232247039
Pubmed

Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases.

ROR1 ROR2

7.70e-06297211713269
Pubmed

D-amino acid oxidase knockdown in the mouse cerebellum reduces NR2A mRNA.

DAO GRIN2A

7.70e-06297220828614
Pubmed

PILRα and PILRβ have a siglec fold and provide the basis of binding to sialic acid.

PILRB PILRA

7.70e-06297224843130
Pubmed

Separate functional properties of NMDARs regulate distinct aspects of spatial cognition.

GRIN2A GRIN2B

7.70e-06297229764972
Pubmed

Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

GRIN2A GRIN2B

7.70e-06297227605622
Pubmed

The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation.

ROR1 ROR2

7.70e-06297234155901
Pubmed

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function.

GRIN2A GRIN2B

7.70e-06297233043365
Pubmed

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

GRIN2A GRIN2B

7.70e-06297230355491
Pubmed

Orphan receptor tyrosine kinases ROR1 and ROR2 in hematological malignancies.

ROR1 ROR2

7.70e-06297222988987
Pubmed

N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease.

GRIN2A GRIN2B

7.70e-06297212127670
Pubmed

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

GRIN2A GRIN2B

7.70e-06297220890276
Pubmed

FUT2 inhibits the EMT and metastasis of colorectal cancer by increasing LRP1 fucosylation.

LRP1 FUT2

7.70e-06297236973740
Pubmed

Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex.

GRIN2A GRIN2B

7.70e-06297216045501
Pubmed

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise.

GRIN2A GRIN2B

7.70e-06297227915379
Pubmed

Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.

ROR1 ROR2

7.70e-06297237430307
Pubmed

Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system.

ROR1 ROR2

7.70e-06297210231392
Pubmed

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory.

GRIN2A GRIN2B

7.70e-06297232179753
Pubmed

Virally mediated knock-down of NR2 subunits ipsilateral to the deprived eye blocks ocular dominance plasticity.

GRIN2A GRIN2B

7.70e-06297216944113
Pubmed

Role of the Ror family receptors in Wnt5a signaling.

ROR1 ROR2

7.70e-06297238587578
Pubmed

Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor.

GRIN2A GRIN2B

7.70e-0629729822733
Pubmed

Expression and subcellular localization of Ror tyrosine kinase receptors are developmentally regulated in cultured hippocampal neurons.

ROR1 ROR2

7.70e-06297212898527
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.

GRIN2A GRIN2B

7.70e-06297215742215
Pubmed

A single-amino-acid substitution in herpes simplex virus 1 envelope glycoprotein B at a site required for binding to the paired immunoglobulin-like type 2 receptor alpha (PILRalpha) abrogates PILRalpha-dependent viral entry and reduces pathogenesis.

PILRB PILRA

7.70e-06297220686018
Pubmed

Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.

ROR1 ROR2

7.70e-06297211429290
Pubmed

Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis.

LRP1 CTSD

7.70e-06297222081071
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

7.70e-06297237657442
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

7.70e-06297238813758
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

7.70e-06297238731978
Pubmed

LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.

GRIN2B LRP1

7.70e-06297223866919
Pubmed

Spinal NR2B phosphorylation at Tyr1472 regulates IRE(-)DMT1-mediated iron accumulation and spine morphogenesis via kalirin-7 in tibial fracture-associated postoperative pain after orthopedic surgery in female mice.

SLC11A2 GRIN2B

7.70e-06297233443215
Pubmed

A novel family of cell surface receptors with tyrosine kinase-like domain.

ROR1 ROR2

7.70e-0629721334494
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

7.70e-06297230269991
Pubmed

Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

GRIN2A GRIN2B

7.70e-06297231498792
Pubmed

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

GRIN2A GRIN2B

7.70e-06297232191258
Pubmed

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.

GRIN2A GRIN2B

7.70e-06297231807283
Pubmed

Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy.

CORIN KIT

7.70e-06297218988802
Pubmed

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.

GRIN2A GRIN2B

7.70e-06297226500840
Pubmed

Neurite extension in central neurons: a novel role for the receptor tyrosine kinases Ror1 and Ror2.

ROR1 ROR2

7.70e-06297215654020
Pubmed

Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.

ROR1 ROR2

7.70e-06297225029443
Pubmed

Chronic early postnatal scream sound stress induces learning deficits and NMDA receptor changes in the hippocampus of adult mice.

GRIN2A GRIN2B

7.70e-06297227015584
Pubmed

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

GRIN2A GRIN2B

7.70e-06297219806658
Pubmed

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.

GRIN2A GRIN2B

7.70e-06297222142193
Pubmed

Identification and characterization of stem cells in prepubertal spermatogenesis in mice.

ALCAM KIT

7.70e-06297212781694
Pubmed

Neutrophil infiltration during inflammation is regulated by PILRα via modulation of integrin activation.

PILRB PILRA

7.70e-06297223142774
Pubmed

Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.

GRIN2A GRIN2B

7.70e-06297233976221
Pubmed

Directional gating of synaptic plasticity by GPCRs and their distinct downstream signalling pathways.

GRIN2A GRIN2B

7.70e-06297222334046
Pubmed

Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development.

ROR1 ROR2

7.70e-06297211455430
Pubmed

Modulation of paired immunoglobulin-like type 2 receptor signaling alters the host response to Staphylococcus aureus-induced pneumonia.

PILRB PILRA

7.70e-06297220065029
Pubmed

Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasion.

ROR1 ROR2

7.70e-06297226515598
Pubmed

Role of N-methyl-d-aspartate receptor subunits GluN2A and GluN2B in auditory thalamocortical long-term potentiation in adult mice.

GRIN2A GRIN2B

7.70e-06297234197904
Pubmed

Roles of NMDA NR2B subtype receptor in prefrontal long-term potentiation and contextual fear memory.

GRIN2A GRIN2B

7.70e-06297216157280
Pubmed

N-Methyl-d-aspartic Acid (NMDA) Receptor Is Involved in the Inhibitory Effect of Ketamine on Human Sperm Functions.

GRIN2A GRIN2B

7.70e-06297234830255
Pubmed

The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development.

DAO LRP1

7.70e-06297217942912
Pubmed

NMDA Receptor C-Terminal Domain Signalling in Development, Maturity, and Disease.

GRIN2A GRIN2B

7.70e-06297236232696
Pubmed

PILRα negatively regulates mouse inflammatory arthritis.

PILRB PILRA

7.70e-06297224935926
Pubmed

Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors.

GRIN2A GRIN2B

7.70e-06297222306487
Pubmed

β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases.

ROR1 ROR2

7.70e-06297226862065
Pubmed

Differential roles of NMDAR subunits 2A and 2B in mediating peripheral and central sensitization contributing to orofacial neuropathic pain.

GRIN2A GRIN2B

7.70e-06297236038077
Pubmed

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior.

GRIN2A GRIN2B

7.70e-06297223201971
Pubmed

Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition.

GRIN2A GRIN2B

7.70e-06297211719203
Pubmed

The Ig-like v-type domain of paired Ig-like type 2 receptor alpha is critical for herpes simplex virus type 1-mediated membrane fusion.

PILRB PILRA

7.70e-06297220573830
Pubmed

ROR1 and ROR2 play distinct and opposing roles in endometrial cancer.

ROR1 ROR2

7.70e-06297229395309
Pubmed

Analysis of correlation between serum D-serine levels and functional promoter polymorphisms of GRIN2A and GRIN2B genes.

GRIN2A GRIN2B

7.70e-06297216266783
Pubmed

Monocyte infiltration into obese and fibrilized tissues is regulated by PILRα.

PILRB PILRA

7.70e-06297226840635
Pubmed

Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains.

GRIN2A GRIN2B

7.70e-06297227839871
Pubmed

Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases.

GRIN2A GRIN2B

7.70e-06297222187052
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease in a sex-specific manner.

GRIN2A GRIN2B

7.70e-06297217569088
Pubmed

Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.

ROR1 ROR2

7.70e-06297224104062
Pubmed

Altered effects of ethanol in NR2A(DeltaC/DeltaC) mice expressing C-terminally truncated NR2A subunit of NMDA receptor.

GRIN2A GRIN2B

7.70e-06297211530236
InteractionBTNL2 interactions

ROR2 CNTNAP1 GPR107 UGT8 IGSF9 GALNT5 SORL1

8.72e-06155957int:BTNL2
InteractionNETO1 interactions

GRIN2A GRIN2B RSPH1

1.63e-0511953int:NETO1
Cytoband7q22.1

PILRB PILRA TMEM225B SPDYE3

1.01e-041139747q22.1
Cytoband2p23

SRD5A2 SLC5A6

5.89e-04179722p23
CytobandEnsembl 112 genes in cytogenetic band chr7q22

PILRB PILRA TMEM225B SPDYE3

1.23e-03219974chr7q22
Cytoband6q13

KHDC1 SLC17A5

3.11e-03399726q13
CytobandEnsembl 112 genes in cytogenetic band chr2p23

SRD5A2 CLIP4 SLC5A6

3.95e-03149973chr2p23
GeneFamilySolute carriers

SLC17A2 SLC11A2 SLC17A3 SLC5A7 SLC39A13 SLC17A5 SLC46A3 SLC22A13 SLC5A6 SLC23A2

2.38e-063956910752
GeneFamilyATP binding cassette subfamily A

ABCA12 ABCA7 ABCA9

1.88e-0514693805
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

2.98e-0476921201
GeneFamilyFibronectin type III domain containing

ASTN2 IGSF9 EGFLAM IGSF9B SORL1

3.63e-04160695555
GeneFamilyReceptor Tyrosine Kinases|CD molecules

ROR1 ROR2 KIT

4.75e-0440693321
GeneFamilyImmunoglobulin like domain containing

MMP23B IGSF9 IGSF9B ALCAM KIT

8.51e-04193695594
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROR1 ROR2 IGSF9 IGSF9B

3.34e-03161694593
GeneFamilyAdenosine receptors|V-set domain containing

PILRB PILRA IGSF9B ALCAM

3.49e-03163694590
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MMP23B ABCA9 CLDN11 NRXN1 LRP1 EGFLAM

2.27e-061749769c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MMP23B ABCA9 CLDN11 NRXN1 LRP1 EGFLAM

2.27e-06174976bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC2 CLIP4 SLC5A6 CLN6 IGSF9 ALCAM

3.88e-06191976b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR1 MMP23B CLIP4 CERCAM ALCAM SORL1

4.00e-061929760dc1f46e40346ed0b286e53b106a812441575100
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIN2A GRIN2B GABBR2 CSMD3 NRXN1 FRRS1L

4.50e-06196976676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellBAL-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

PILRA CLIP4 LRP1 CTSD GAA SORL1

4.91e-061999764518ffa51ead9da1ddf07bf048b18602e50f0f84
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PILRA LRP1 ALCAM CTSD GAA SORL1

5.05e-06200976a2548b0c77ba1616638351b111cce2fe0cacaa95
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PILRA LRP1 ALCAM CTSD GAA SORL1

5.05e-06200976e4a499b69554f78161c2c47199da77c201910e73
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR1 ROR2 MMP23B CLDN11 CERCAM EGFLAM

5.05e-06200976d64895354218ebd0217011bae0967a6883bbd1cd
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLC5A7 CLDN11 LCTL UGT8 GALNT5

5.34e-0611597515b2c11225802cc15c01165d84a755432f02d82f
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_1|Striatum / BrainAtlas - Mouse McCarroll V32

OPN4 CASR CLDN11 LCTL UGT8

5.57e-06116975c19974992b315fb873664fe3f5077ff8e907e30c
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CLDN11 LCTL UGT8 CERCAM EGFLAM

6.31e-06119975ec3af1253f03b3ec403f73243237acf08ad56789
ToppCellfacs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC17A2 PRLHR PILRA GRIN2A ITGAL

1.34e-0513997596e6fed23e7a69f678f85e8e2fe77a7491586b4b
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1|Striatum / BrainAtlas - Mouse McCarroll V32

CASR CLDN11 LGI3 UGT8 CORIN

1.59e-051449759d6133558728fa148050eb4f0be33756d71310b0
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P1|Thalamus / BrainAtlas - Mouse McCarroll V32

CASR CLDN11 LCTL UGT8 CORIN

1.76e-05147975a21b63d0d3aec9ffadf3fac833a0a24da58a95bf
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCB5 GRIN2A GRIN2B CSMD3 NRXN1

1.82e-05148975d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR2B MATK CERCAM IGSF9 ALCAM

2.07e-051529757e686721b95c837f2b0d5116927c8ecacef055ee
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Arhgap36_Hmcn1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC5A7 CSMD3 ADRA1A ALCAM KIT

2.13e-051539759c6fce56300ba5053efda59a438d63a808c497c0
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR2B MATK SLC22A13 UGT8 CERCAM

2.20e-051549751e32969bee810adaf2d560f0824a16227df513d8
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PILRA ABCC5 ITGAL LRP1 IGSF9

2.49e-05158975b0508a600994090c6aafd8d779437190a33ad821
ToppCellfacs-Lung-EPCAM-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PILRA ABCC5 ITGAL LRP1 IGSF9

2.49e-05158975a816cc095452308d06f87b77467e2a8c6361fd2a
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC17A2 PILRA MATK ITGAL FITM1

2.64e-051609755d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

DAO CASR ITGAL CORIN

2.69e-0579974cd182dbc8d0ccc2406e78c9ba71476c1f463359b
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P1-Tnr-Polydendrocyte.Tnr.Pdgfa-Tmem2_(Pdgfa)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

DAO CASR ITGAL CORIN

2.69e-0579974bcb9181d7de7a385b890523299f8290836aa536e
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC17A3 GRIN2B CSMD3 FRRS1L UGT8

2.81e-05162975bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

GRIN2B GABBR2 CSMD3 TMEM229B NRXN1

3.06e-051659759795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SLC17A3 ROR2 SLC22A13 SLC5A6

3.63e-05171975007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SLC17A3 ROR2 SLC22A13 SLC5A6

3.63e-051719758e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCelldroplet-Liver-Npc-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PILRA ITGAL CLDN11 LRP1 CTSD

3.84e-051739759ba55e21d1037ec3150d77895e52f0b051df65da
ToppCellwk_20-22-Epithelial-PNS|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GRIN2B LCTL NRXN1 UGT8 EGFLAM

3.84e-0517397517b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGAL LRP1 MS4A14 CTSD GAA

3.95e-05174975d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC17A2 SLC17A3 SRD5A2 ADRA1A GYS2

4.06e-051759757f74961436f88c0e380819095e6104489914d765
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

SLC17A2 SLC17A3 SRD5A2 ADRA1A GYS2

4.06e-05175975bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell5'-GW_trimst-1.5-SmallIntestine-Epithelial-epithelial_progenitor_cell-Proximal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B1 GYS2 UGT8 IGSF9 FUT2

4.06e-051759756759d200a133034756de9cdf2d5daceca927aac9
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABBR2 MFSD12 CLIP4 SLC5A6 ALCAM

4.06e-051759750992de1c7bffcb6890584357a7a0a8955927da6c
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PILRA ITGAL LRP1 CTSD VAV1

4.17e-051769756548797336c9f4ca0f38e74a2c629e2a4defa252
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 CLDN11 ADRA1A ALCAM KIT

4.28e-05177975fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

SLC5A7 GRIN2B NRXN1 EGFLAM IGSF9B

4.28e-05177975621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_LGI2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 ADRA1A EGFLAM ALCAM KIT

4.52e-051799758dd10e3a9ab39d9a770cecac6e2ed3676b79e906
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRLHR SLC5A7 GRIN2B CLDN11 CHAC1

4.52e-05179975d96741c5c551e36421b2ad938072ab7d506c3835
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR2 MMP23B ADRA1A LRP1 ASTN2

4.64e-0518097508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ROR2 SLC5A7 ATP8B1 GRIN2B SLC23A2

4.89e-05182975f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC5 ITGAL LRP1 CTSD VAV1

5.15e-05184975fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR2 MMP23B LRP1 CERCAM EGFLAM

5.28e-05185975785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR2 MMP23B LRP1 CERCAM EGFLAM

5.28e-0518597597a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCellMild-NK|World / Disease group and Cell class

MATK ROR1 SRD5A2 ABCA9 KIT

5.28e-051859750565b7c464e1a09e596f5a0b363d2dc9b55c3c50
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR2 MMP23B LRP1 CERCAM EGFLAM

5.42e-0518697594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellMyeloid-B_(Activated_Macrophage)|World / shred on cell class and cell subclass (v4)

ABCC5 ITGAL LRP1 CTSD VAV1

5.42e-0518697533d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC5 ITGAL LRP1 CTSD VAV1

5.42e-051869757950e03ea080238c168b9d807e217f459acdfb28
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL13A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

ROR2 GRIN2B NRXN1 EXOC3L4 EGFLAM

5.56e-05187975e04fb35f2f5b120659d06b5ae427ab1ec56d5c36
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Rassf10|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASR CLDN11 UGT8 CERCAM

5.56e-05959740ac6cba7e0ed6083f777287f39a871461fa1bca4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC11A2 ROR2 ATP8B1 GRIN2B SLC23A2

5.85e-05189975c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 ROR2 ADRA1A FRRS1L CORIN

5.99e-05190975562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 ROR2 ADRA1A FRRS1L CORIN

5.99e-05190975f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR1 MMP23B LRP1 CERCAM GAA

6.15e-051919759214655dca96d766737c9f30b624d7fe7050342e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 ROR2 GRIN2A ABCA9 LRP1

6.15e-0519197539092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ROR1 ROR2 GRIN2A ABCA9 LRP1

6.15e-05191975ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellMS-NK-|MS / Condition, Cell_class and T cell subcluster

PILRB MATK ROR1 CTSD KIT

6.30e-05192975f97f5f8226f5c65ca93072ef35d753231bee2490
ToppCellMS-NK|MS / Condition, Cell_class and T cell subcluster

PILRB MATK ROR1 CTSD KIT

6.30e-05192975f44f5dd30db169fdd16c9d706d17ad44907a17af
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR1 ROR2 MMP23B ADRA1A LRP1

6.30e-05192975deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CSMD3 ABCA9 NRXN1 EGFLAM ALCAM

6.46e-05193975cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR2 MMP23B ADRA1A LRP1 ASTN2

6.46e-05193975fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SERINC2 ATP8B1 GRIN2B CLDN11 CLN6

6.46e-051939757261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HTR2B MMP23B ABCA9 CLDN11 LRP1

6.61e-0519497502b8102be9414d6964cd71019613edff6d88b893
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR1 ROR2 MMP23B CLDN11 CERCAM

6.78e-051959750866aaf053762d1a021fcbccff058526078a99da
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC11A2 CLIP4 SLC17A5 LRP1 ALCAM

6.78e-051959759d649ac7d2af313481069c95349efc0c68449e2b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ROR2 MMP23B ABCA9 LRP1 CERCAM

6.78e-051959751236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIN2A GABBR2 CSMD3 NRXN1 SORL1

6.78e-051959752e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN11 PTPRA NRXN1 LGI3 UGT8

6.94e-05196975256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR1 MMP23B LRP1 SERINC3 CERCAM

6.94e-05196975b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROR1 MMP23B LRP1 SERINC3 CERCAM

6.94e-05196975787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Deep_Layer-37|World / Primary Cells by Cluster

GRIN2B GABBR2 NRXN1 FRRS1L KIT

7.11e-0519797500d756bc0231e1b3b88430214338c1059cb11106
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-PNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

MATK GRIN2B GABBR2 NRXN1 FRRS1L

7.11e-0519797510e72b425a2bcba35e63a5b074d3dedcd49a762e
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIN2A GRIN2B GABBR2 CSMD3 NRXN1

7.28e-05198975c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

ROR2 MMP23B ABCA9 ADRA1A LRP1

7.28e-051989753ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIN2A GRIN2B GABBR2 CSMD3 NRXN1

7.28e-051989756d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MATK MFSD12 TMEM147 ALCAM CTSD

7.28e-051989753b4611c9ee4d42e042a29ddb4580a95938d87d65
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIN2A GRIN2B GABBR2 CSMD3 NRXN1

7.28e-051989758ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GRIN2A GRIN2B GABBR2 CSMD3 NRXN1

7.28e-051989754ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

ROR2 MMP23B CLDN11 LRP1 CERCAM

7.28e-0519897574f2c7ef702b25a5b99e56121229e678ed992524
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

ROR2 MMP23B ABCA9 CLDN11 CERCAM

7.46e-0519997512133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ROR2 MMP23B ABCA9 ADRA1A CERCAM

7.46e-051999757a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCellPBMC-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

PILRA CLIP4 LRP1 CTSD SORL1

7.46e-05199975ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCellmild_COVID-19-NK|mild_COVID-19 / disease group, cell group and cell class (v2)

MATK MMP23B ITGAL CERCAM CTSD

7.46e-051999754854f25ee436e1cf577744373ffd87b1221d2b88
ToppCellBAL-Severe-cDC_0|Severe / Compartment, Disease Groups and Clusters

PILRA LRP1 CTSD GAA SORL1

7.46e-05199975d39be8b173156bf87baddd3caed4b35597c53ea1
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PILRA MFSD12 LRP1 ALCAM CTSD

7.64e-05200975eac46978e2b3d38cf42b44f7b0350d0489d036b3
ToppCell10x5'-Lung-Myeloid_Mac-Alveolar_macrophages|Lung / Manually curated celltypes from each tissue

PILRA SERINC2 LRP1 CTSD GAA

7.64e-052009753b236900df407bf5a8c44e76d003a7a37d251db6
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_1|Neuronal / cells hierarchy compared to all cells using T-Statistic

ABCB5 CLDN11 ADRA1A ALCAM KIT

7.64e-052009759f21e4e0913d8ef95a3f771dff0abaad8fe1d9f2
ToppCellNS-control-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SERINC2 ALCAM GALNT5 FUT2 CTSD

7.64e-05200975d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBCB CLDN11 LGI3 UGT8 CERCAM

7.64e-052009753ce8a2db8c25e1169a0a544f644a63104749c5ee
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ROR1 ROR2 CASR KHDC1 LRP1

7.64e-052009755ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

GRIN2B GABBR2 TBCB NRXN1 ALCAM

7.64e-05200975db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|Fibroblasts / Location, Cell class and cell subclass

ROR2 MMP23B CLDN11 LRP1 CERCAM

7.64e-05200975f62833c63f9c6a94b6cc2ba8e2f960e67f093f48
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macrophage_intravascular|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PILRA MFSD12 LRP1 ALCAM CTSD

7.64e-0520097577a68e8fd97a3f3467d25032067fd7ad52ab8522
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

GRIN2B GABBR2 TBCB NRXN1 ALCAM

7.64e-0520097530a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellKidney-Tubules|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

CASR SERINC2 UGT8 CTSD SORL1

7.64e-052009750726456906e078244a9cff35aee8c5bce4566fb1
ToppCellBiopsy_IPF-Mesenchymal-HAS1_High_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

ROR1 MMP23B ABCA9 CLDN11 CERCAM

7.64e-05200975d02e256b5d65a5c982ba5696bc7e077281ca3e24
ToppCellsevere-NK|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MATK MMP23B ITGAL PTPRA CERCAM

7.64e-05200975d6767f06fe13be8110a86c2a6029be2dd9ce666c
ToppCellBronchial-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SLC5A7 ABCA9 NRXN1 ASTN2

1.21e-04116974b0a3c109c5f20ab699e53bf8ab3903d102f5f315
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

OPN4 SLC17A3 VAV1

1.29e-0445973668add3b0e69b851942df9c52850ed2285e08494
Drug3-isoreserpine

HTR2B ABCA12 ABCB5 ABCC5 ABCA7 ABCA9 SLC17A5 ADRA1A SORL1

1.13e-07190969CID000005052
DiseaseAdenocarcinoma of large intestine

MATK ROR1 ROR2 MSH2 KIT

1.36e-0596935C1319315
DiseaseAutistic Disorder

DAO GRIN2A GRIN2B GABBR2 CSMD3 NRXN1 ASTN2

1.94e-05261937C0004352
Diseasealcohol use disorder measurement

HECTD4 GABBR2 CSMD3 SLC39A13 FUT2 SORL1

6.12e-05214936EFO_0009458
DiseaseAlzheimer's disease (is_implicated_in)

GRIN2B ADRA1A LRP1 CTSD SORL1

6.29e-05132935DOID:10652 (is_implicated_in)
DiseaseColorectal Carcinoma

SLC11A2 ABCA12 ABCB5 ABCC5 MSH2 GRIN2A CSMD3 ABCA9 LRP1 SORL1

7.46e-057029310C0009402
Diseasephospholipase D3 measurement

MFSD12 CTSD

1.46e-046932EFO_0802866
DiseaseAdult neuronal ceroid lipofuscinosis

CLN6 CTSD

1.46e-046932cv:C0022797
DiseaseCommon Migraine

LRP1 ASTN2

2.04e-047932C0338480
DiseaseColorectal Neoplasms

ABCA12 ABCB5 ABCC5 MSH2 GRIN2A ABCA9

2.50e-04277936C0009404
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

2.72e-048932DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

2.72e-048932DOID:1561 (biomarker_via_orthology)
DiseaseNeuronal ceroid lipofuscinosis

CLN6 CTSD

3.49e-049932cv:C0027877
Diseasealcohol consumption measurement

ACSS1 GRIN2B CSMD3 BIRC6 SLC39A13 CLIP4 NRXN1 ASTN2 IGSF9B FUT2 KIT SORL1

5.26e-0412429312EFO_0007878
DiseaseSemantic-Pragmatic Disorder

GRIN2A NRXN1

5.31e-0411932C0454655
DiseaseAuditory Processing Disorder, Central

GRIN2A NRXN1

5.31e-0411932C0751257
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

5.31e-0411932DOID:9279 (implicated_via_orthology)
DiseasePancreatic Ductal Adenocarcinoma

ABCA12 ABCB5

5.31e-0411932C1335302
DiseaseLanguage Delay

GRIN2A NRXN1

5.31e-0411932C0023012
DiseaseLanguage Development Disorders

GRIN2A NRXN1

5.31e-0411932C0023014
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

5.31e-0411932DOID:8725 (is_marker_for)
DiseaseSpeech Delay

GRIN2A NRXN1

5.31e-0411932C0241210
Diseasehypertension (is_implicated_in)

PRLHR ADRA1A CORIN MOV10

5.93e-04121934DOID:10763 (is_implicated_in)
DiseaseX-11444 measurement

SRD5A2 BIRC6

7.49e-0413932EFO_0021237
DiseaseBipolar Disorder

ROR1 DAO GRIN2A GRIN2B ADRA1A NRXN1 ASTN2

7.91e-04477937C0005586
Diseasebitter alcoholic beverage consumption measurement

ACSS1 ADRA1A IGSF9B SORL1

8.45e-04133934EFO_0010092
Diseaseceramide measurement

ROR2 ATP8B1 ABCA7 UGT8 CORIN

9.03e-04235935EFO_0010222
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

SLC5A7 CHRND

1.15e-0316932C0751885
Diseasemigraine without aura, susceptibility to, 4

LRP1 ASTN2

1.15e-0316932MONDO_0011847
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

SLC5A7 CHRND

1.30e-0317932C0751883
Diseasefamily history of Alzheimer’s disease

PILRA ABCA7 SORL1

1.48e-0371933EFO_0009268
DiseaseAlcoholic Intoxication, Chronic

SRD5A2 SERINC2 GRIN2A GRIN2B SLC17A5

1.61e-03268935C0001973
DiseaseCongenital Myasthenic Syndromes, Presynaptic

SLC5A7 CHRND

1.62e-0319932C0751884
Diseasenicotine dependence symptom count, depressive symptom measurement

DAO GRIN2B TMEM229B

1.74e-0375933EFO_0007006, EFO_0009262
Diseasevisual cortical surface area measurement

ALCAM MOV10

1.80e-0320932EFO_0004771
DiseaseSchizophrenia

SRD5A2 DAO GRIN2A GRIN2B ADRA1A PTPRA NRXN1 LRP1 ASTN2

1.89e-03883939C0036341
Diseaseschizophrenia (is_implicated_in)

DAO GRIN2A GRIN2B

1.94e-0378933DOID:5419 (is_implicated_in)
DiseaseAntimigraine preparation use measurement

LRP1 ASTN2

1.98e-0321932EFO_0009939
Diseaseaspartate aminotransferase measurement

SRD5A2 HECTD4 ATP8B1 BIRC6 MFSD12 SLC17A5 ASTN2 CTSD MOV10

2.21e-03904939EFO_0004736
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B

2.38e-0323932DOID:12858 (is_implicated_in)
Diseasemean corpuscular hemoglobin concentration

SLC17A2 SLC11A2 HECTD4 ABCC5 HNRNPUL1 ABCA7 WDHD1 SLC5A6 SLC23A2 GAA

2.53e-0311059310EFO_0004528
Diseasemigraine disorder, Headache

NEMP1 LRP1 ASTN2

2.57e-0386933HP_0002315, MONDO_0005277
DiseaseMyasthenic Syndromes, Congenital

SLC5A7 CHRND

2.59e-0324932C0751882
Diseasecholelithiasis

ATP8B1 TMEM147 FUT2

2.74e-0388933EFO_0004799
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

SRD5A2 CSMD3 BIRC6

2.74e-0388933EFO_0803332
Diseaseresponse to TNF antagonist, joint damage measurement

GABBR2 CSMD3

2.81e-0325932EFO_0004653, EFO_0005413
DiseaseDepressive Symptoms

SLC5A7 DAO

3.04e-0326932C0086132

Protein segments in the cluster

PeptideGeneStartEntry
IDFSGPTIYGWAVLA

VDAC3

131

Q9Y277
YAAAGFPAWEVYLRA

EXOC3L4

301

Q17RC7
YGFVYWLPPAIFRSS

CHRND

136

Q07001
VWIGYVSSGVNPLVY

HTR2B

366

P41595
DIGWITGHSYVVYGP

ACSS1

336

Q9NUB1
RLLNTAGGYPYSFWI

CNTNAP1

681

P78357
YLGGAPSAYWLVRAT

EGFLAM

511

Q63HQ2
AATTGGSVYWYFVLL

BIRC6

1441

Q9NR09
WGFSISYICSPGYEL

CSMD3

3251

Q7Z407
LRISGLYPSAYWFGQ

ABCA9

1056

Q8IUA7
LYPSAYWFGQALVDV

ABCA9

1061

Q8IUA7
FWYGTSLILNGEPGY

ABCB5

306

Q2M3G0
LIAWYVRNVFPGTYG

ABCA12

1266

Q86UK0
IVWISFIPAYASTYG

CASR

816

P41180
PFSAIFEVLGYWAFG

ADRA1A

81

P35348
GSPYVVLFDIGYSAW

GYS2

111

P54840
TTNFAPGYWYGIELE

CLIP4

506

Q8N3C7
WPYTTLERGYDLVTG

ASTN2

561

O75129
PSYRGFLIFWGYIIV

ATP8B1

381

O43520
DPLTDLRYVWGGFVY

ABCA7

491

Q8IZY2
SQGFPIEGWAVVYYI

GPR107

321

Q5VW38
PDYGYGWFHTSLILE

DAO

126

P14920
ISETLGWPFVFYIFG

SLC17A3

146

O00476
GVLLWEVFSYGRAPY

MATK

411

P42679
VYGTNPLEFEFLWGS

MAGEE2

241

Q8TD90
GIFLWELFSLGSSPY

KIT

856

P10721
PFAVTLYGGEVYWTD

LRP1

1481

Q07954
SFYYGTFPLGFSWGV

LCTL

31

Q6UWM7
PIYVILVGGWSFSLY

NEMP1

216

O14524
FVLWEVGYPLYIYGS

FAM205A

6

Q6ZU69
FVLWDVGYPLYTYGS

FAM205C

6

A6NFA0
YFGPAALYIWAVGIL

SLC11A2

366

P49281
VFPTEVWTALLNYGY

NRXN1

626

Q9ULB1
APSFYWEIEIVSYGD

HECTD4

1991

Q9Y4D8
FFGWSAYVPEGLLTS

OPN4

206

Q9UHM6
VPWSVYGVYIQAAGG

ABCC5

841

O15440
GGSVEIPFSFYYPWE

PILRA

46

Q9UKJ1
TAYEWVNPAAYGLVV

HECTD1

1086

Q9ULT8
AAFNYWHPEIVYSGG

DPH7

201

Q9BTV6
VGAAVGTFAWYLTYG

FITM1

251

A5D6W6
YFFELGTYDPGLDVW

GALNT5

681

Q7Z7M9
YYLFAWGPAIQGSIT

FRRS1L

226

Q9P0K9
FGIWAAYLTGGDTIY

FUT2

291

Q10981
PLWILGDVFIGRYYT

CTSD

381

P07339
FGYGSLVWRPDFAYS

CHAC1

36

Q9BUX1
LGVKYAVFSTGLWYP

UGT8

151

Q16880
AVFSTGLWYPAEVGA

UGT8

156

Q16880
IVSFGYSLYAGWIGA

CLDN11

151

O75508
GPGVYSNVSYFVEWI

CORIN

1016

Q9Y5Q5
AEVTGYFPLGTWYDL

GAA

761

P10253
GYPFWGALIFILTGY

MS4A14

81

Q96JA4
WAVFPNYFGGSELVV

ITIH6

491

Q6UXX5
PSKFHGYAYDGIWVI

GABBR2

351

O75899
YGVLIFIYGWPFLQT

KHDC1

21

Q4VXA5
GGLFTYVLFWTFLYG

EMC6

91

Q9BV81
GLPGLVVAGYSYWTL

CERCAM

461

Q5T4B2
TGTAPGLLLFFYFWA

SLC22A13

256

Q9Y226
ETQGWILGSFFYGYI

SLC17A5

106

Q9NRA2
TAAWVLPFTSGGFLY

SLC39A13

316

Q96H72
VFRPGLGWYTVNSAY

ALCAM

21

Q13740
ATPEWAALLYYGPFI

MFSD12

121

Q6NUT3
YGPFIVIFQFGWAST

MFSD12

131

Q6NUT3
TYDGFGLAWAISEYI

MSH2

756

P43246
YWPSDGLVSYGDITV

PTPRA

646

P18433
GYPLTIEGFAYLWSG

HNRNPUL1

231

Q9BUJ2
TAEAVYVPGYGLAWA

SLC5A7

71

Q9GZV3
TWTGPRNVVYGIFYA

SORL1

1861

Q92673
IRAYATVIDGPEYFW

TDRD6

1521

O60522
SWGYGCTLRDFPGVY

PRSS29P

281

A6NIE9
LTLAYAFEPRGWVFG

PRLHR

116

P49683
SVLWPYYVLGFGIFL

TMEM225B

146

P0DP42
WILPLTYSGAVFYTG

TAAR8

156

Q969N4
FPGVTSVWALFIYGT

TMEM229B

41

Q8NBD8
FVGYFPATVLWELLG

MOV10

206

Q9HCE1
FDDSEYWVLGPTRYS

MMP23B

181

O75900
LGVPSEIYRFGTQYW

SLC5A6

86

Q9Y289
VAWYPGFTFLLSAGL

SLC46A3

411

Q7Z3Q1
VLWEVFSYGLQPYCG

ROR2

681

Q01974
TFIYPDGSRYEGEWA

RSPH1

81

Q8WYR4
TPEVRAGYLGYTVTW

ITGAL

396

P20701
PSGLYYWYLVTEGQI

CLN6

216

Q9NWW5
VLWEIFSFGLQPYYG

ROR1

681

Q01973
AFFDSIVGVAAYVGW

PIK3R4

596

Q99570
IPGDTAWLLYDTYGF

AARS1

406

P49588
FSYLPISPTFVGYTW

SLC23A2

616

Q9UGH3
YFTVLPGWEYRQEAG

IGSF9B

421

Q9UPX0
VIAYFSRAGLPSWQY

SPDYE3

426

A6NKU9
YLAWIGFSAEGTPCY

WDHD1

626

O75717
YGRVGWFPANYVEED

VAV1

826

P15498
YVGLTDFKPGYWIGV

TBCB

181

Q99426
ALSWPFIFYIFGSTG

SLC17A2

206

O00624
YPDGWYTDIRFSLGV

SRD5A2

136

P31213
PNYTYEVGSWIGFAI

TECR

246

Q9NZ01
FDGGYLQRFSVWYTP

IGSF9

531

Q9P2J2
WYPYGIAQVSFADLL

nan

106

Q6ZUG5
GGSVEIPFSFYYPWE

PILRB

46

Q9UKJ0
VGSFYIPGGYFSSVW

SERINC3

146

Q13530
LFLATFFPTWEGGIY

TMEM147

51

Q9BVK8
LYEWRNYGPGFIDST

ZNF426

251

Q9BUY5
PDGSFTNIWFYFGVV

SERINC2

151

Q96SA4
VAQLFGGSYIYHWDP

LGI3

296

Q8N145
LGLTGYDFFWIVPSL

GRIN2A

246

Q12879
GYGYTWIVPSLVAGD

GRIN2B

251

Q13224