Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	TRPM4 CACHD1 SLC15A3 KCNK4 SLC16A12 SLC22A12 SLCO5A1 SLC25A22 SLC9A2 SLCO1C1 P2RX3 SLC16A6 MFSD14B ABCC8 SLC49A4 SLC9B2 KCNK5 SLC15A5 SLC2A13 SLC5A8 ATP4A ABCC10	1.40e-06	1180	118	22	GO:0022857
GeneOntologyMolecularFunction	transporter activity	TMEM30B TRPM4 CACHD1 SLC15A3 KCNK4 SLC16A12 SLC22A12 SLCO5A1 SLC25A22 SLC9A2 SLCO1C1 P2RX3 SLC16A6 MFSD14B ABCC8 SLC49A4 SLC9B2 KCNK5 SLC15A5 SLC2A13 SLC5A8 ATP4A ABCC10	1.63e-06	1289	118	23	GO:0005215
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC15A3 SLC16A12 SLCO5A1 SLC25A22 SLC9A2 SLCO1C1 ABCC8 SLC9B2 SLC15A5 SLC2A13 SLC5A8 ATP4A ABCC10	4.98e-06	477	118	13	GO:0022804
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC15A3 SLC16A12 SLCO5A1 SLC25A22 SLC9A2 SLCO1C1 SLC9B2 SLC15A5 SLC2A13 SLC5A8	1.05e-05	296	118	10	GO:0015291
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TRPM4 CACHD1 SLC15A3 KCNK4 SLC25A22 SLC9A2 P2RX3 ABCC8 SLC9B2 KCNK5 SLC2A13 SLC5A8 ATP4A	1.53e-04	664	118	13	GO:0008324
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TRPM4 CACHD1 SLC15A3 KCNK4 SLC25A22 SLC9A2 ABCC8 SLC9B2 KCNK5 SLC2A13 SLC5A8 ATP4A	3.40e-04	627	118	12	GO:0022890
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	CCR10 ERBB2 MLNR FFAR1 INSR C5AR2 NMUR1 OR10C1 IL1RL2 ADGRA2 P2RX3 P2RY11 ABCC8 CD79A MRGPRX4 ADGRF4 LTB4R TM2D1 ADGRA3	3.58e-04	1353	118	19	GO:0004888
GeneOntologyMolecularFunction	solute:proton symporter activity	SLC15A3 SLC25A22 SLC2A13	4.21e-04	25	118	3	GO:0015295
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC15A3 SLC25A22 SLC9A2 ABCC8 SLC9B2 SLC2A13 SLC5A8 ATP4A	4.24e-04	301	118	8	GO:0022853
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	TRPM4 CACHD1 SLC15A3 KCNK4 SLC25A22 SLC9A2 ABCC8 SLC9B2 KCNK5 SLC2A13 SLC5A8 ATP4A ABCC10	5.45e-04	758	118	13	GO:0015318
GeneOntologyMolecularFunction	mannosyltransferase activity	TMEM260 TMTC4 ALG3	5.92e-04	28	118	3	GO:0000030
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	TRPM4 CACHD1 SLC15A3 KCNK4 SLC25A22 SLC9A2 P2RX3 ABCC8 SLC9B2 KCNK5 SLC2A13 SLC5A8 ATP4A	8.27e-04	793	118	13	GO:0015075
GeneOntologyMolecularFunction	proton transmembrane transporter activity	SLC15A3 SLC25A22 SLC9A2 SLC9B2 SLC2A13 ATP4A	8.86e-04	188	118	6	GO:0015078
GeneOntologyMolecularFunction	dolichyl-phosphate-mannose-protein mannosyltransferase activity	TMEM260 TMTC4	9.47e-04	8	118	2	GO:0004169
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO1 RAB5IF NOMO2 NOMO3	1.34e-07	9	120	4	GO:0160063
GeneOntologyBiologicalProcess	protein insertion into ER membrane	NOMO1 RAB5IF NOMO2 NOMO3	3.04e-05	31	120	4	GO:0045048
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO1 RAB5IF NOMO2 NOMO3	1.32e-07	9	121	4	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO1 RAB5IF NOMO2 NOMO3	1.02e-06	14	121	4	GO:0072379
GeneOntologyCellularComponent	basal plasma membrane	ERBB2 C5AR2 SLC16A12 SLCO5A1 CD1D SLCO1C1 SLC16A6 SLC9B2 ABCC10	2.21e-04	354	121	9	GO:0009925
GeneOntologyCellularComponent	lysosome	VPS18 TM9SF1 INSR UBXN6 VPS16 SLC15A3 EPG5 CD1D SLC49A4 SLC9B2 SLC2A13 ABCC10 PCSK9 VAT1	2.53e-04	811	121	14	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	VPS18 TM9SF1 INSR UBXN6 VPS16 SLC15A3 EPG5 CD1D SLC49A4 SLC9B2 SLC2A13 ABCC10 PCSK9 VAT1	2.53e-04	811	121	14	GO:0000323
GeneOntologyCellularComponent	basal part of cell	ERBB2 C5AR2 SLC16A12 SLCO5A1 CD1D SLCO1C1 SLC16A6 SLC9B2 ABCC10	3.58e-04	378	121	9	GO:0045178
GeneOntologyCellularComponent	basolateral plasma membrane	ERBB2 SLC16A12 SLCO5A1 CD1D SLCO1C1 SLC16A6 SLC9B2 ABCC10	5.56e-04	320	121	8	GO:0016323
GeneOntologyCellularComponent	CORVET complex	VPS18 VPS16	6.85e-04	7	121	2	GO:0033263
GeneOntologyCellularComponent	vacuole	VPS18 TM9SF1 INSR UBXN6 VPS16 SLC15A3 EPG5 CD1D SLC49A4 SLC9B2 SLC2A13 ABCC10 PCSK9 VAT1	8.21e-04	913	121	14	GO:0005773
GeneOntologyCellularComponent	lysosomal membrane	VPS18 TM9SF1 UBXN6 VPS16 SLC15A3 CD1D SLC49A4 ABCC10 PCSK9	1.48e-03	462	121	9	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	VPS18 TM9SF1 UBXN6 VPS16 SLC15A3 CD1D SLC49A4 ABCC10 PCSK9	1.48e-03	462	121	9	GO:0098852
Domain	MFS_dom	SLC15A3 SLC16A12 SLC22A12 SLCO5A1 SLCO1C1 SLC16A6 MFSD14B SLC49A4 SLC15A5 SLC2A13	1.53e-08	134	120	10	IPR020846
Domain	MFS	SLC16A12 SLC22A12 SLCO5A1 SLCO1C1 SLC16A6 MFSD14B SLC49A4 SLC2A13	4.73e-07	108	120	8	PS50850
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.03e-06	4	120	3	PF09430
Domain	DUF2012	NOMO1 NOMO2 NOMO3	1.03e-06	4	120	3	IPR019008
Domain	Carb-bd-like_fold	NOMO1 NOMO2 NOMO3	1.41e-05	8	120	3	IPR013784
Domain	Growth_fac_rcpt_	ERBB2 INSR LAMC1 VWCE SVEP1 FBN1 MEGF6	6.70e-05	156	120	7	IPR009030
Domain	CarboxyPept_regulatory_dom	NOMO1 NOMO2 NOMO3	7.06e-05	13	120	3	IPR014766
Domain	-	NOMO1 NOMO2 NOMO3	7.06e-05	13	120	3	2.60.40.1120
Domain	CarboxyPept-like_regulatory	NOMO1 NOMO2 NOMO3	1.65e-04	17	120	3	IPR008969
Domain	-	ISLR2 INSR ADAMTSL3 IL1RL2 ADGRA2 NOMO1 CD1D FNDC7 NOMO2 CD79A IGSF1 NOMO3 ADGRA3	3.39e-04	663	120	13	2.60.40.10
Domain	POT_fam	SLC15A3 SLC15A5	4.04e-04	5	120	2	IPR000109
Domain	PTR2	SLC15A3 SLC15A5	4.04e-04	5	120	2	PF00854
Domain	Ig-like_fold	ISLR2 INSR ADAMTSL3 IL1RL2 ADGRA2 NOMO1 CD1D FNDC7 NOMO2 CD79A IGSF1 NOMO3 ADGRA3	6.13e-04	706	120	13	IPR013783
Domain	Lipome_HGMIC_fus_partner-like	LHFPL1 LHFPL6	8.42e-04	7	120	2	IPR019372
Domain	L_HMGIC_fpl	LHFPL1 LHFPL6	8.42e-04	7	120	2	PF10242
Domain	Recep_L_domain	ERBB2 INSR	8.42e-04	7	120	2	PF01030
Domain	Furin-like	ERBB2 INSR	8.42e-04	7	120	2	PF00757
Domain	Rcpt_L-dom	ERBB2 INSR	8.42e-04	7	120	2	IPR000494
Domain	Furin-like_Cys-rich_dom	ERBB2 INSR	8.42e-04	7	120	2	IPR006211
Domain	-	ERBB2 INSR	8.42e-04	7	120	2	3.80.20.20
Domain	GPS	ADGRA2 ADGRF4 ADGRA3	1.46e-03	35	120	3	PF01825
Domain	MFS_1	SLC16A12 SLC22A12 SLC16A6 MFSD14B	1.53e-03	77	120	4	PF07690
Domain	MFS	SLC16A12 SLC22A12 SLC16A6 MFSD14B	1.53e-03	77	120	4	IPR011701
Domain	GPS	ADGRA2 ADGRF4 ADGRA3	1.58e-03	36	120	3	PS50221
Domain	GPS	ADGRA2 ADGRF4 ADGRA3	1.71e-03	37	120	3	IPR000203
Domain	GPCR_2_extracellular_dom	ADGRA2 ADGRF4 ADGRA3	2.15e-03	40	120	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	ADGRA2 ADGRF4 ADGRA3	2.15e-03	40	120	3	PS00649
Domain	G_PROTEIN_RECEP_F2_3	ADGRA2 ADGRF4 ADGRA3	2.15e-03	40	120	3	PS50227
Domain	EGF_CA	VWCE SVEP1 FBN1 MEGF6	2.29e-03	86	120	4	PF07645
Domain	OA_transporter	SLCO5A1 SLCO1C1	2.59e-03	12	120	2	IPR004156
Domain	OATP	SLCO5A1 SLCO1C1	2.59e-03	12	120	2	PF03137
Domain	Na_H_Exchanger	SLC9A2 SLC9B2	3.54e-03	14	120	2	PF00999
Domain	Cation/H_exchanger	SLC9A2 SLC9B2	3.54e-03	14	120	2	IPR006153
Domain	EGF_Ca-bd_CS	VWCE SVEP1 FBN1 MEGF6	3.55e-03	97	120	4	IPR018097
Domain	EGF_CA	VWCE SVEP1 FBN1 MEGF6	3.82e-03	99	120	4	PS01187
Domain	ASX_HYDROXYL	VWCE SVEP1 FBN1 MEGF6	3.95e-03	100	120	4	PS00010
Domain	7tm_2	ADGRA2 ADGRF4 ADGRA3	4.07e-03	50	120	3	PF00002
Domain	G_PROTEIN_RECEP_F2_2	ADGRA2 ADGRF4 ADGRA3	4.07e-03	50	120	3	PS00650
Domain	2pore_dom_K_chnl	KCNK4 KCNK5	4.07e-03	15	120	2	IPR003280
Domain	PI3/4_kinase_CS	PI4KA PRKDC	4.07e-03	15	120	2	IPR018936
Domain	EGF	LAMC1 VWCE ADAM22 SVEP1 FBN1 MEGF6	4.13e-03	235	120	6	SM00181
Domain	-	PI4KA PRKDC	4.63e-03	16	120	2	1.10.1070.11
Domain	PI3Kc	PI4KA PRKDC	4.63e-03	16	120	2	SM00146
Domain	EGF-type_Asp/Asn_hydroxyl_site	VWCE SVEP1 FBN1 MEGF6	4.87e-03	106	120	4	IPR000152
Domain	EGF-like_dom	LAMC1 VWCE ADAM22 SVEP1 FBN1 MEGF6	5.46e-03	249	120	6	IPR000742
Domain	PI3_PI4_kinase	PI4KA PRKDC	5.86e-03	18	120	2	PF00454
Domain	PI3_4_KINASE_1	PI4KA PRKDC	5.86e-03	18	120	2	PS00915
Domain	PI3_4_KINASE_2	PI4KA PRKDC	5.86e-03	18	120	2	PS00916
Domain	PI3/4_kinase_cat_dom	PI4KA PRKDC	5.86e-03	18	120	2	IPR000403
Domain	PI3_4_KINASE_3	PI4KA PRKDC	5.86e-03	18	120	2	PS50290
Domain	Furin_repeat	ERBB2 INSR	5.86e-03	18	120	2	IPR006212
Domain	FU	ERBB2 INSR	5.86e-03	18	120	2	SM00261
Domain	EGF_1	LAMC1 VWCE ADAM22 SVEP1 FBN1 MEGF6	6.12e-03	255	120	6	PS00022
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	TRPM4 SLC15A3 SLC22A12 SLC25A22 SLC9A2 PSME4 SLCO1C1 SLC9B2 SLC2A13 SLC5A8 ATP4A ABCC10 PCSK9	4.77e-05	681	74	13	MM14985
Pathway	KEGG_MEDICUS_REFERENCE_AUTOPHAGOSOME_AND_LYSOSOME_FUSION_TETHERING_FACTOR	VPS18 VPS16 EPG5	7.40e-05	16	74	3	M47978
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	TRPM4 SLC15A3 SLC22A12 SLC25A22 SLC9A2 PSME4 SLCO1C1 SLC9B2 SLC2A13 SLC5A8 ATP4A ABCC10 PCSK9	1.05e-04	736	74	13	M27287
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC15A3 SLC22A12 SLC25A22 SLC9A2 SLCO1C1 SLC2A13 SLC5A8	2.46e-04	238	74	7	MM15076
Pathway	REACTOME_TYROSINE_CATABOLISM	FAH TAT	2.69e-04	5	74	2	MM15554
Pathway	KEGG_MEDICUS_REFERENCE_TYROSINE_DEGRADATION	FAH TAT	2.69e-04	5	74	2	M47619
Pathway	REACTOME_TYROSINE_CATABOLISM	FAH TAT	2.69e-04	5	74	2	M27834
Pathway	WP_TYROSINE_METABOLISM_AND_RELATED_DISORDERS	FAH TAT	2.69e-04	5	74	2	M45543
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLC15A3 SLC22A12 SLC25A22 SLC9A2 SLCO1C1 SLC2A13 SLC5A8	3.24e-04	249	74	7	M5988
Pathway	REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	CCR10 MLNR FFAR1 C5AR2 PF4 NMUR1 P2RY11 LTB4R	3.26e-04	330	74	8	M18334
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	CCR10 MLNR FFAR1 C5AR2 NMUR1 P2RY11 LTB4R	4.20e-04	260	74	7	M39397
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO1 RAB5IF NOMO2 NOMO3	1.73e-08	9	121	4	36261522
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO1 NOMO2 NOMO3	4.11e-08	3	121	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO1 NOMO2 NOMO3	4.11e-08	3	121	3	25576386
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO1 NOMO2 NOMO3	1.64e-07	4	121	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO1 NOMO2 NOMO3	1.64e-07	4	121	3	9267806
Pubmed	Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b.	VPS18 VPS16 CD1D	8.15e-07	6	121	3	21802320
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TRPM4 STK36 ERBB2 PCNX3 CUL9 RALGAPA2 ADGRA2 BAHD1 EML3 SLC25A22 PSME4 MEGF6 PI4KA KCNK5 PRKDC ABCC10	1.52e-06	1105	121	16	35748872
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	INSR LAMC1 SLC16A12 SLCO1C1 CLDN5 SLC2A13	1.90e-06	105	121	6	30280653
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO1 NOMO2 NOMO3	2.27e-06	8	121	3	15257293
Pubmed	Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.	ADGRA2 FREM2 PRKDC NOMO3 ADGRA3	3.81e-06	67	121	5	21875946
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RCE1 ERBB2 GPAA1 TM9SF1 LAMC1 CACHD1 ADAM22 NOMO1 FBN1 NOMO2 TMEM245 ALG3 PRAF2 ADGRA3 MAN1B1 PCSK9	4.41e-06	1201	121	16	35696571
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TMEM30B TRPM4 ERBB2 VPS18 GPAA1 TM9SF1 VPS16 SLC16A6 TMTC4 PRKDC METTL16 PRAF2 ABCC10 ADGRA3 MAN1B1	4.43e-06	1061	121	15	33845483
Pubmed	High-throughput engineering of the mouse genome coupled with high-resolution expression analysis.	C5AR2 NMUR1 ADGRA2	4.84e-06	10	121	3	12730667
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO1 NOMO2 NOMO3	6.64e-06	11	121	3	32820719
Pubmed	Variants in genes encoding the SUR1-TRPM4 non-selective cation channel and sudden infant death syndrome (SIDS): potentially increased risk for cerebral edema.	TRPM4 ABCC8	1.20e-05	2	121	2	35474489
Pubmed	The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia.	TRPM4 ABCC8	1.20e-05	2	121	2	27246103
Pubmed	Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury.	TRPM4 ABCC8	1.20e-05	2	121	2	34309670
Pubmed	Sur1-Trpm4 Cation Channel Expression in Human Cerebral Infarcts.	TRPM4 ABCC8	1.20e-05	2	121	2	26172285
Pubmed	Differential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.	CCR10 ITK	1.20e-05	2	121	2	20483745
Pubmed	On potential interactions between non-selective cation channel TRPM4 and sulfonylurea receptor SUR1.	TRPM4 ABCC8	1.20e-05	2	121	2	22291026
Pubmed	Development of the tight-skin phenotype in immune-deficient mice.	FBN1 PRKDC	1.20e-05	2	121	2	11263788
Pubmed	Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury.	TRPM4 ABCC8	1.20e-05	2	121	2	30484364
Pubmed	Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation.	ERBB2 PRKDC	1.20e-05	2	121	2	21723633
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ISLR2 ERBB2 FLYWCH1 CACHD1 KEAP1 ADGRA2 BAHD1 TUBGCP6 PSME4 IGSF1	1.71e-05	529	121	10	14621295
Pubmed	Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein.	ADGRA2 ADGRA3	3.59e-05	3	121	2	15021905
Pubmed	Amplification of the STOML3, FREM2, and LHFP genes is associated with mesenchymal differentiation in gliosarcoma.	FREM2 LHFPL6	3.59e-05	3	121	2	22538188
Pubmed	Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.	KEAP1 PRKDC	3.59e-05	3	121	2	18687751
Pubmed	Expansion, in vivo-ex vivo cycling, and genetic manipulation of primary human hepatocytes.	FAH PRKDC	3.59e-05	3	121	2	31915293
Pubmed	SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling.	TRPM4 ABCC8	3.59e-05	3	121	2	28906027
Pubmed	Sulfonylurea Receptor 1, Transient Receptor Potential Cation Channel Subfamily M Member 4, and KIR6.2:Role in Hemorrhagic Progression of Contusion.	TRPM4 ABCC8	3.59e-05	3	121	2	30160201
Pubmed	NHE10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected].	SLC9A2 SLC9B2	3.59e-05	3	121	2	18269914
Pubmed	GPAA1 promotes gastric cancer progression via upregulation of GPI-anchored protein and enhancement of ERBB signalling pathway.	ERBB2 GPAA1	3.59e-05	3	121	2	31118109
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	EML3 NOMO1 NOMO2 ATP4A NOMO3	4.29e-05	110	121	5	27889896
Pubmed	Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.	INSR SLCO1C1 CLDN5	5.22e-05	21	121	3	23137377
Pubmed	LHFP, a novel translocation partner gene of HMGIC in a lipoma, is a member of a new family of LHFP-like genes.	LHFPL1 LHFPL6	7.17e-05	4	121	2	10329012
Pubmed	The insulin receptor content is increased in breast cancers initiated by three different oncogenes in transgenic mice.	ERBB2 INSR	7.17e-05	4	121	2	9342439
Pubmed	Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain.	LAMC1 PRKDC	7.17e-05	4	121	2	35121993
Pubmed	AKT2 maintains brain endothelial claudin-5 expression and selective activation of IR/AKT2/FOXO1-signaling reverses barrier dysfunction.	INSR CLDN5	7.17e-05	4	121	2	30574832
Pubmed	The interaction of mammalian Class C Vps with nSec-1/Munc18-a and syntaxin 1A regulates pre-synaptic release.	VPS18 VPS16	7.17e-05	4	121	2	17027648
Pubmed	Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study.	INSR ABCC8	7.17e-05	4	121	2	37052755
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	STK36 CUL9 CACHD1 BAHD1 IGSF1	9.49e-05	130	121	5	12421765
Pubmed	Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes.	ADGRA2 ADAM22 SLC15A5	1.13e-04	27	121	3	24550280
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CABLES2 ERBB2 INSR CACHD1 RALGAPA2 NOMO1 PI4KA VAT1	1.18e-04	421	121	8	36976175
Pubmed	The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase.	SLC9A2 ATP4A	1.19e-04	5	121	2	12195293
Pubmed	Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase.	VPS18 VPS16	1.19e-04	5	121	2	16203730
Pubmed	Glucose elicits cephalic-phase insulin release in mice by activating KATP channels in taste cells.	P2RX3 ABCC8	1.19e-04	5	121	2	28148491
Pubmed	Molecular cloning and characterization of human VPS18, VPS 11, VPS16, and VPS33.	VPS18 VPS16	1.19e-04	5	121	2	11250079
Pubmed	A Case Study on the Keap1 Interaction with Peptide Sequence Epitopes Selected by the Peptidomic mRNA Display.	LAMC1 KEAP1	1.19e-04	5	121	2	31169361
Pubmed	Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.	SLC9A2 ATP4A	1.19e-04	5	121	2	16870707
Pubmed	B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.	CD79A PRKDC	1.19e-04	5	121	2	29551267
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRA2 ADGRF4 ADGRA3	1.40e-04	29	121	3	15203201
Pubmed	Hepatic lipase maturation: a partial proteome of interacting factors.	NOMO1 NOMO2 NOMO3	1.72e-04	31	121	3	19136429
Pubmed	CORVET, CHEVI and HOPS - multisubunit tethers of the endo-lysosomal system in health and disease.	VPS18 VPS16	1.78e-04	6	121	2	31092635
Pubmed	Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7.	VPS18 VPS16	1.78e-04	6	121	2	11382755
Pubmed	Novel lethal mouse mutants produced in balancer chromosome screens.	ERBB2 NXN	1.78e-04	6	121	2	16466971
Pubmed	C5a regulates NKT and NK cell functions in sepsis.	C5AR2 CD1D	1.78e-04	6	121	2	22058413
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	LAMC1 FREM2	1.78e-04	6	121	2	17462874
Pubmed	Effect of the mouse scid mutation on meiotic recombination.	ME1 PRKDC	1.78e-04	6	121	2	8672126
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRA2 ADGRF4 ADGRA3	2.08e-04	33	121	3	25713288
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	NOMO1 NOMO2 NOMO3	2.08e-04	33	121	3	30783098
Pubmed	Expression pattern of LRR and Ig domain-containing protein (LRRIG protein) in the early mouse embryo.	ISLR2 ADGRA2 ADGRA3	2.27e-04	34	121	3	18848646
Pubmed	Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.	TM9SF1 DHRS7B ABCC8 PRAF2	2.37e-04	86	121	4	25044020
Pubmed	RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.	VPS18 VPS16	2.49e-04	7	121	2	25445562
Pubmed	Novel function of LHFPL2 in female and male distal reproductive tract development.	LHFPL1 LHFPL6	2.49e-04	7	121	2	26964900
Pubmed	Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.	KEAP1 PRKDC	2.49e-04	7	121	2	24011591
Pubmed	Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein.	KCNK4 KCNK5	2.49e-04	7	121	2	18516069
Pubmed	There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.	ADGRA2 ADGRA3	2.49e-04	7	121	2	12565841
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	KEAP1 DHRS7B NOMO1 TUBGCP6 SLC25A22 NOMO2 PI4KA NOMO3 VAT1	2.80e-04	606	121	9	36538041
Pubmed	The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression.	NOMO1 NOMO3 VAT1	2.93e-04	37	121	3	8076819
Pubmed	SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.	VPS18 VPS16	3.32e-04	8	121	2	19109425
Pubmed	Nuclear localization of Beclin 1 promotes radiation-induced DNA damage repair independent of autophagy.	NLRP2 PRKDC	3.32e-04	8	121	2	28345663
Pubmed	EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.	LAMC1 FBN1	3.32e-04	8	121	2	32948785
Pubmed	Identification of mouse Vps16 and biochemical characterization of mammalian class C Vps complex.	VPS18 VPS16	3.32e-04	8	121	2	14623309
Pubmed	Recruitment of VPS33A to HOPS by VPS16 Is Required for Lysosome Fusion with Endosomes and Autophagosomes.	VPS18 VPS16	3.32e-04	8	121	2	25783203
Pubmed	Structural basis of Vps33A recruitment to the human HOPS complex by Vps16.	VPS18 VPS16	3.32e-04	8	121	2	23901104
Pubmed	Identification of the switch in early-to-late endosome transition.	VPS18 VPS16	3.32e-04	8	121	2	20434987
Pubmed	The HOPS complex mediates autophagosome-lysosome fusion through interaction with syntaxin 17.	VPS18 VPS16	3.32e-04	8	121	2	24554770
Pubmed	A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.	KCNK4 KCNK5	3.32e-04	8	121	2	26919430
Pubmed	The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets.	C5AR2 PF4	3.32e-04	8	121	2	34099640
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	TRPM4 ERBB2 GPAA1 TM9SF1 SLC25A22 TMEM245 SLC49A4 PRAF2	3.71e-04	499	121	8	22810586
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBN1 MEGF6	4.25e-04	9	121	2	12122015
Pubmed	Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.	ERBB2 KEAP1	4.25e-04	9	121	2	26517842
Pubmed	Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.	VPS18 VPS16	4.25e-04	9	121	2	25266290
Pubmed	Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin.	ERBB2 NXN	4.25e-04	9	121	2	20011118
Pubmed	Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia.	CCR10 CD1D	4.25e-04	9	121	2	17954569
Pubmed	Soluble SORLA Enhances Neurite Outgrowth and Regeneration through Activation of the EGF Receptor/ERK Signaling Axis.	ERBB2 INSR	4.25e-04	9	121	2	32601248
Pubmed	Proteome-wide analysis of phospho-regulated PDZ domain interactions.	ADAM22 CD1D SLC15A5	4.27e-04	42	121	3	30126976
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	CDC42BPG NLRP2 EML3 TUBGCP6 PSME4	4.64e-04	183	121	5	31932471
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	STK36 RALGAPA2 ADAMTSL3 NWD2	4.72e-04	103	121	4	10574462
Pubmed	Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation.	ADGRA2 CLDN5	5.30e-04	10	121	2	28803732
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C5AR2 FBN1	5.30e-04	10	121	2	30429287
Pubmed	Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: linkage of candidate genes using two sib-pair based variance components analyses.	INSR ABCC8	5.30e-04	10	121	2	18828733
Pubmed	Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.	CDC42BPG SLC22A12	5.30e-04	10	121	2	21768215
Pubmed	Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.	VPS18 VPS16	5.30e-04	10	121	2	26463206
Pubmed	An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex.	VPS18 VPS16	5.30e-04	10	121	2	18799622
Pubmed	Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking.	VPS18 VPS16	6.47e-04	11	121	2	18552835
Pubmed	SVEP1 is an endogenous ligand for the orphan receptor PEAR1.	LAMC1 SVEP1	6.47e-04	11	121	2	36792666
Pubmed	Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.	CD1D CD79A	6.47e-04	11	121	2	29249358
Pubmed	Potassium leak channels and the KCNK family of two-P-domain subunits.	KCNK4 KCNK5	7.74e-04	12	121	2	11256078
Pubmed	Nonsyndromic Genetic Hyperinsulinism Overview	INSR ABCC8	7.74e-04	12	121	2	20301549
GeneFamily	Solute carriers	SLC15A3 SLC16A12 SLC22A12 SLCO5A1 SLC25A22 SLC9A2 SLCO1C1 SLC16A6 SLC49A4 SLC9B2 SLC15A5 SLC2A13 SLC5A8	7.89e-09	395	75	13	752
GeneFamily	Immunoglobulin like domain containing\|Adhesion G protein-coupled receptors, subfamily A	ADGRA2 ADGRA3	5.08e-05	3	75	2	911
GeneFamily	Immunoglobulin like domain containing	ISLR2 ADAMTSL3 IL1RL2 ADGRA2 IGSF1	1.24e-03	193	75	5	594
GeneFamily	ATP binding cassette subfamily C	ABCC8 ABCC10	1.29e-03	13	75	2	807
GeneFamily	Potassium two pore domain channel subfamily K	KCNK4 KCNK5	1.72e-03	15	75	2	277
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	CABLES2 ERBB2 PCNX3 TM9SF1 ADGRA2 DHRS7B ZDHHC24 MFSD14B TMEM245 SLC49A4 LHFPL6 ALG3 ADGRA3	1.64e-05	681	121	13	M5314
Coexpression	CUI_DEVELOPING_HEART_TRABECULAR_ATRIAL_CARDIOMYOCYTE	ERBB2 GPAA1 INSR NOMO1 FREM2 TMEM245 PRKDC	2.02e-05	179	121	7	M39308
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	CABLES2 ERBB2 PCNX3 TM9SF1 ADGRA2 DHRS7B ZDHHC24 MFSD14B TMEM245 SLC49A4 LHFPL6 ALG3 ADGRA3	2.29e-05	703	121	13	MM1055
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 HIGD1B IL1RL2 SLCO5A1 FBN1 MEGF6 CLDN5	8.11e-07	187	121	7	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	LAMC1 ADAMTSL3 NXN SVEP1 FBN1 LHFPL6 SLC2A13	1.07e-06	195	121	7	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TMEM30B HIGD1B LAMC1 ADAMTSL3 ADGRA2 FBN1 LHFPL6	1.11e-06	196	121	7	cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TMEM30B HIGD1B LAMC1 ADAMTSL3 ADGRA2 FBN1 LHFPL6	1.11e-06	196	121	7	44e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ERBB2 HIGD1B PF4 IL1RL2 SLC22A12 FNDC7	1.81e-06	134	121	6	9a9fa63b40d9bf94995d70ef19d2548cb418b138
ToppCell	Hippocampus-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ERBB2 HIGD1B PF4 IL1RL2 SLC22A12 FNDC7	1.81e-06	134	121	6	22c64b8c405f3752331b81c611d8e62bd58c07f7
ToppCell	PND01-03-samps-Mesenchymal-Pericyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	HIGD1B NMUR1 ADAMTSL3 TMEM178A ABCC8 LHFPL6	3.76e-06	152	121	6	fc9472bc19f997103da535b035105f01429cb08e
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ERBB2 C5AR2 NMUR1 VARS2 SVEP1 ABCC10	4.05e-06	154	121	6	ea5d0da5dd8ccfc19969aec35f044db77d589f54
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3\|TCGA-Adrenal / Sample_Type by Project: Shred V9	C5AR2 PCDH12 CD1D SLCO1C1 TMTC4 LHFPL6	5.23e-06	161	121	6	52239a887799362256ecd7e740b716b88ed59a62
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMC1 ADAMTSL3 SLC16A12 SVEP1 FBN1 LHFPL6	1.05e-05	182	121	6	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADML2 KLHL40 EXTL1 SLC9A2 ABCC8 IGSF1	1.19e-05	186	121	6	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADML2 KLHL40 EXTL1 SLC9A2 ABCC8 IGSF1	1.19e-05	186	121	6	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2\|lymph-node_spleen / Manually curated celltypes from each tissue	GPAA1 PCNX3 ADGRA2 FAH CD1D SLC49A4	1.23e-05	187	121	6	3c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCell	RV-07._Pericyte\|World / Chamber and Cluster_Paper	HIGD1B ADAMTSL3 ADGRA2 SLC16A12 P2RX3 LHFPL6	1.23e-05	187	121	6	dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADML2 KLHL40 EXTL1 SLC9A2 ABCC8 IGSF1	1.31e-05	189	121	6	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADML2 KLHL40 EXTL1 SLC9A2 ABCC8 IGSF1	1.31e-05	189	121	6	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B LAMC1 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.39e-05	191	121	6	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	LAMC1 ADAMTSL3 SVEP1 FBN1 LHFPL6 SLC2A13	1.39e-05	191	121	6	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VPS18 FLYWCH1 SLC16A12 NOMO2 PI4KA TAT	1.43e-05	192	121	6	522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCell	proximal-3-Hematologic-Platelet/Megakaryocyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VPS18 FLYWCH1 SLC16A12 NOMO2 PI4KA TAT	1.43e-05	192	121	6	f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	LAMC1 ADAMTSL3 SLC16A12 SVEP1 FBN1 LHFPL6	1.43e-05	192	121	6	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	proximal-Hematologic-Platelet/Megakaryocyte-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	VPS18 FLYWCH1 SLC16A12 NOMO2 PI4KA TAT	1.43e-05	192	121	6	57899a905ca3e336bb7f31edc6418a2546b9891a
ToppCell	368C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EXTL1 NLRP2 FBN1 CLDN5 CPLANE1 TCTN1	1.47e-05	193	121	6	5f5904cec8b2967154ef2eab3c48f51df53aca4a
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	LAMC1 ADAMTSL3 SVEP1 FBN1 LHFPL6 SLC2A13	1.51e-05	194	121	6	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 NXN ADGRA2 SLCO1C1 MEGF6 TMTC4	1.61e-05	196	121	6	dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell	Tracheal-10x5prime-Stromal-Pericyte\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCR10 HIGD1B KLHL40 ADGRA2 SLC16A12 SLCO1C1	1.75e-05	199	121	6	cefc3b50f65e95da850e4720c7b44bf584073491
ToppCell	Tracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_systemic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCR10 HIGD1B KLHL40 ADGRA2 SLC16A12 SLCO1C1	1.75e-05	199	121	6	aaa460c389cd6d38a13ba1a446f91a94f9573ad8
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CCR10 PCDH12 FREM2 CLDN5 LTB4R	2.94e-05	131	121	5	d5bc40cd585582856881081b7130dec3515b4ae0
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM30B ADAMTSL3 SLC9B2 KCNK5 CD79A	3.40e-05	135	121	5	4451c44f3ad788437f4e2ae81049fbbab53f967e
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TMEM30B ADAMTSL3 SLC9B2 KCNK5 CD79A	3.40e-05	135	121	5	45f67f33c8320d9fb6dbceae603b564f6a8ffd1e
ToppCell	PND07-28-samps-Mesenchymal-Pericyte-pericyte_F\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ISLR2 HIGD1B NMUR1 ADAMTSL3 TMEM178A	5.61e-05	150	121	5	2d0d6dc07dcfe28e3d7694c52d15d17dae2fd47b
ToppCell	PND07-28-samps-Mesenchymal-Pericyte\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	ISLR2 HIGD1B NMUR1 ADAMTSL3 TMEM178A	5.61e-05	150	121	5	5b111ec11a642d63fafa7e1422e36f81a2776531
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NMUR1 VWCE SLC22A12 FREM2 MEGF6	7.18e-05	158	121	5	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NMUR1 VWCE SLC22A12 FREM2 MEGF6	7.18e-05	158	121	5	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HIGD1B ADGRA2 SLC16A12 SLCO1C1 LHFPL6	7.39e-05	159	121	5	7a5c94c87b73f928d4daee507f32cbe7d90e4478
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIGD1B NMUR1 ADAMTSL3 TMEM178A LHFPL6	7.84e-05	161	121	5	82ed45f144a07856fe92d37426c5f92e259a03a9
ToppCell	facs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 ME1 SLC22A12 FAH SLC5A8	8.81e-05	165	121	5	906321cb5f299d77436fb5540fd8c52d7532beca
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCR10 HIGD1B KLHL40 ADAM22 SLC16A12	8.81e-05	165	121	5	3d14f37b8a9c0ddc1130e60a2e08556bad1fb855
ToppCell	facs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCR10 ME1 SLC22A12 FAH SLC5A8	8.81e-05	165	121	5	02a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	RALGAPA2 NXN FBN1 LHFPL6 CLDN5	9.32e-05	167	121	5	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	Thalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Pvalb_(Non-anterior_nuclei)\|Thalamus / BrainAtlas - Mouse McCarroll V32	FFAR1 NMUR1 KCNK4 PCSK9	9.32e-05	87	121	4	fd0df79b02f96463a6bad90dcd019c59c8e3eb0e
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 RALGAPA2 NXN ADGRA2 MEGF6	9.59e-05	168	121	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FREM2 TMTC4 SLC2A13 SLC5A8 CPLANE1	9.59e-05	168	121	5	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 RALGAPA2 NXN ADGRA2 MEGF6	9.59e-05	168	121	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_F\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	NDUFAF5 HIGD1B NMUR1 ADAMTSL3 ABCC8	1.01e-04	170	121	5	71718dcebd48105994c313bb55babc70301170a0
ToppCell	Endothelial-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	PCDH12 ADGRA2 LHFPL1 FBN1 CLDN5	1.04e-04	171	121	5	07ff7059071da83da1d8f266a586573920d75b58
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SVEP1 FREM2 SLC9A2 SLC5A8 VWA5B1	1.07e-04	172	121	5	8b396d1e9173da104d467e42286379fe07cee257
ToppCell	Adult-Mesenchymal-pericyte_cell-D231\|Adult / Lineage, Cell type, age group and donor	HIGD1B ADAMTSL3 ADGRA2 SLCO1C1 LHFPL6	1.07e-04	172	121	5	858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ISLR2 SVEP1 FBN1 SLCO1C1 LHFPL6	1.19e-04	176	121	5	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAH FREM2 MEGF6 TAT PCSK9	1.19e-04	176	121	5	8e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FAH FREM2 MEGF6 TAT PCSK9	1.19e-04	176	121	5	ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ISLR2 SVEP1 FBN1 SLCO1C1 LHFPL6	1.19e-04	176	121	5	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B ADAMTSL3 SLC16A12 TMEM178A LHFPL6	1.22e-04	177	121	5	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	INSR SLC16A12 SLC22A12 KCNK5 SLC5A8	1.22e-04	177	121	5	2f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell	IIH-CD8-antiviral_CD4\|IIH / Condition, Cell_class and T cell subcluster	TUBGCP6 SLC25A22 TMTC4 P2RY11 SLC2A13	1.22e-04	177	121	5	fe73608c40701eca88b260aeb5c0640d7bee72ba
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B ADAMTSL3 SLC16A12 TMEM178A LHFPL6	1.22e-04	177	121	5	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Plasma_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	CCR10 HIGD1B LHFPL1 CD79A	1.26e-04	94	121	4	4b6623de5a517ebf5df865e0dcd615111622ad3e
ToppCell	facs-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B NMUR1 ADAMTSL3 SLC22A12 TMEM178A	1.29e-04	179	121	5	7078022e60faa86444f2a2c6eb9f767cc66b5cfa
ToppCell	facs-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B NMUR1 ADAMTSL3 SLC22A12 TMEM178A	1.29e-04	179	121	5	d4a975d8ffa5e77fb5c0ec05bf9c8f843c77ce07
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B ADAMTSL3 SLC22A12 TMEM178A LHFPL6	1.32e-04	180	121	5	f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIGD1B ADAMTSL3 SLC22A12 TMEM178A LHFPL6	1.32e-04	180	121	5	dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYADML2 ADAMTSL3 ADAM22 SLC9A2 TMEM178A	1.32e-04	180	121	5	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	10x5'-GI_small-bowel-Lymphocytic_B_plasma\|GI_small-bowel / Manually curated celltypes from each tissue	CCR10 INSR LAMC1 CD1D CD79A	1.36e-04	181	121	5	9b33f531c8ac776706ec7e2d47e95ba30b6ce13c
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	ISLR2 ADAMTSL3 ADAM22 SVEP1 FBN1	1.36e-04	181	121	5	bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCell	10x5'-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells\|GI_small-bowel / Manually curated celltypes from each tissue	CCR10 INSR LAMC1 CD1D CD79A	1.36e-04	181	121	5	a0549a8c2b5b30e91fae3052f398e48baa45d7ff
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMC1 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.39e-04	182	121	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B_plasma-Plasma_cells\|GI_small-bowel / Manually curated celltypes from each tissue	CCR10 INSR LAMC1 CD1D CD79A	1.43e-04	183	121	5	ab5aaafcfd7b97330be6774be4c72611ca85257c
ToppCell	LA-07._Pericyte\|World / Chamber and Cluster_Paper	HIGD1B ADAMTSL3 SLC16A12 P2RX3 LHFPL6	1.43e-04	183	121	5	e3835db4795362b0442d5893baf2a78efcc20428
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_B_plasma\|GI_small-bowel / Manually curated celltypes from each tissue	CCR10 INSR LAMC1 CD1D CD79A	1.43e-04	183	121	5	193bfb787c1b36c8fabf4b00fafb5b398de6b999
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	HIGD1B ADAMTSL3 SLC16A12 P2RX3 LHFPL6	1.43e-04	183	121	5	273db6a3b00a93ca852498471187b642b5368185
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	INSR SLC16A12 SLC22A12 KCNK5 SLC5A8	1.47e-04	184	121	5	9434731f651820b05335085582960f08fbf895de
ToppCell	facs-Heart-LA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 NXN ADGRA2 P2RX3 MEGF6	1.51e-04	185	121	5	1ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCell	facs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 NXN ADGRA2 P2RX3 MEGF6	1.51e-04	185	121	5	b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMC1 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.51e-04	185	121	5	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RALGAPA2 ADAMTSL3 NXN LHFPL6 CLDN5	1.51e-04	185	121	5	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	LA-07._Pericyte\|LA / Chamber and Cluster_Paper	HIGD1B ADAMTSL3 SLC16A12 P2RX3 LHFPL6	1.51e-04	185	121	5	ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	RALGAPA2 ADAMTSL3 NXN LHFPL6 CLDN5	1.51e-04	185	121	5	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	LV-07._Pericyte\|LV / Chamber and Cluster_Paper	HIGD1B ADAMTSL3 SLC16A12 P2RX3 LHFPL6	1.51e-04	185	121	5	acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTSL3 ADGRA2 FBN1 SLCO1C1 LHFPL6	1.54e-04	186	121	5	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2\|TCGA-Kidney / Sample_Type by Project: Shred V9	PCDH12 ADGRA2 FBN1 SLCO1C1 LHFPL6	1.54e-04	186	121	5	1e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell	RV-07._Pericyte\|RV / Chamber and Cluster_Paper	HIGD1B ADAMTSL3 SLC16A12 P2RX3 LHFPL6	1.54e-04	186	121	5	c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCR10 HIGD1B ADAMTSL3 SLCO1C1 LHFPL6	1.58e-04	187	121	5	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.58e-04	187	121	5	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.58e-04	187	121	5	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.58e-04	187	121	5	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HIGD1B ADAMTSL3 ADGRA2 SLCO1C1 LHFPL6	1.58e-04	187	121	5	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 HIGD1B FBN1 ABCC8 CLDN5	1.62e-04	188	121	5	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL3 SVEP1 FBN1 MEGF6 LHFPL6	1.62e-04	188	121	5	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	LAMC1 ADAMTSL3 SVEP1 FBN1 LHFPL6	1.62e-04	188	121	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	CACHD1 RALGAPA2 NXN ABCC8 CLDN5	1.62e-04	188	121	5	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ISLR2 ADGRA2 CD1D MEGF6 LHFPL6	1.62e-04	188	121	5	c90669b51e1902fe7726555290c91c92a911df83
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NXN ADGRA2 FBN1 MEGF6 CLDN5	1.62e-04	188	121	5	26915db8863f4115b46a81982e187322e21600fd
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NXN ADGRA2 FBN1 MEGF6 CLDN5	1.62e-04	188	121	5	3f76c0f912f8f023ea425be7f43593b3d7f967e3
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NXN ADGRA2 FBN1 MEGF6 CLDN5	1.62e-04	188	121	5	61ee7b152745164293d8a44ef91ee2393efbdca5
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 VWCE NXN ADGRA2 MEGF6	1.66e-04	189	121	5	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	CCR10 HIGD1B PF4 ADGRA2 LHFPL6	1.66e-04	189	121	5	f4865b7db16de15120504147a8016ac522ad242a
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 VWCE NXN ADGRA2 MEGF6	1.66e-04	189	121	5	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIGD1B NMUR1 ADAMTSL3 TMEM178A LHFPL6	1.66e-04	189	121	5	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ISLR2 RALGAPA2 NXN FBN1 CLDN5	1.70e-04	190	121	5	876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HIGD1B NMUR1 ADAMTSL3 TMEM178A LHFPL6	1.70e-04	190	121	5	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
Disease	Tyrosinemia, Type III	FAH TAT	4.58e-05	3	116	2	C0268623
Disease	Tyrosinemia, Type I	FAH TAT	4.58e-05	3	116	2	C0268490
Disease	Tyrosinemias	FAH TAT	4.58e-05	3	116	2	C0268483
Disease	Tyrosine Transaminase Deficiency Disease	FAH TAT	4.58e-05	3	116	2	C0268487
Disease	hepatitis A virus cellular receptor 2 measurement	ITK NOMO3	4.22e-04	8	116	2	EFO_0008151
Disease	Familial hyperinsulinism	INSR ABCC8	4.22e-04	8	116	2	cv:C3888018
Disease	Marfan Syndrome, Type I	LAMC1 FBN1	5.42e-04	9	116	2	C4721845
Disease	interleukin 1 receptor-like 1 measurement	IL1RL2 SLC9A2	8.23e-04	11	116	2	EFO_0008168
Disease	gallbladder neoplasm	ERBB2 KEAP1	8.23e-04	11	116	2	C0016978
Disease	Marfan Syndrome	LAMC1 FBN1	8.23e-04	11	116	2	C0024796
Disease	Malignant neoplasm of gallbladder	ERBB2 KEAP1	8.23e-04	11	116	2	C0153452
Disease	adult onset asthma	ADAMTSL3 IL1RL2 ITK SLC9A2	1.23e-03	118	116	4	EFO_1002011
Disease	interleukin 18 receptor 1 measurement	IL1RL2 SLC9A2	1.56e-03	15	116	2	EFO_0008178
Disease	Monogenic diabetes	INSR ABCC8	1.77e-03	16	116	2	C3888631
Disease	Familial aplasia of the vermis	CPLANE1 TCTN1	2.78e-03	20	116	2	cv:C0431399
Disease	Joubert syndrome 1	CPLANE1 TCTN1	3.06e-03	21	116	2	C4551568

Protein segments in the cluster

Peptide	Gene	Start	Entry
GVGSPYVSRLLGICL	ERBB2	776	P04626
QYGLPIDGCIGRRFF	EPG5	1326	Q9HCE0
ARCGLNPVLYAFLGL	CCR10	301	P46092
RLSYCGGGEALAVPF	C8orf82	126	Q6P1X6
RFYLIAGGIPLIICG	ADGRA2	886	Q96PE1
IYFLCAGLRLRGPLA	ADGRA2	941	Q96PE1
RFYLIGGGIPIIVCG	ADGRA3	876	Q8IWK6
FGFRGALPKLGICAG	ALG3	226	Q92685
VIGFAIGYGCPLIIA	ADGRF4	516	Q8IZF3
GYLLCTNIGNIPRLG	ADAM22	601	Q9P0K1
KPCYFGNLLLGIVGV	CACHD1	471	Q5VU97
FLLFLLSAVYLGPGC	CD79A	16	P11912
LSVGGSGYVCPLLIR	ASTE1	106	Q2TB18
PLRLLYLCPAGGGAA	ISLR2	526	Q6UXK2
PCFVGLLGEKYGNIR	NWD2	116	Q9ULI1
GVLPLRGFLGIAGFC	RAB5IF	61	Q9BUV8
GKFRLRGLLPGCVYH	NOMO3	1001	P69849
DRLCVGAAGGFALYP	CDC42BPG	1236	Q6DT37
LLGPGGYLFLLGDCQ	PCDH12	11	Q9NPG4
FGRCYLALGLLKLVG	ABCC10	281	Q5T3U5
GKFRLRGLLPGCVYH	NOMO2	1001	Q5JPE7
GLGCGLPLLLTLAAY	P2RY11	211	Q96G91
VPIGLGGCLVVAAYR	HIGD1B	31	Q9P298
YVFPGVALGVVACGL	ME1	456	P48163
GGLGCPFDRLVVVYT	MYADML2	221	A6NDP7
GYLVVPSGAYILGRC	LYZL4	11	Q96KX0
DLCYGALAAIPGLRP	TAT	351	P17735
PFLLGVGGCYFRTLL	NMUR1	126	Q9HB89
GALLFPLLSLGLYPC	GPAA1	596	O43292
GRLFCIFYALVGIPL	KCNK4	116	Q9NYG8
SGACCPLGVKLYRLG	FNDC7	626	Q5VTL7
GQARPLEFLRTCYGG	FLYWCH1	266	Q4VC44
GLYYGGRLLCGASLV	TMPRSS15	801	P98073
CRVGILSGLGALPRY	FREM2	216	Q5SZK8
RRPLLAGYALGVGLF	RCE1	281	Q9Y256
AALLYGFCLGAIKTP	PCNX3	961	Q9H6A9
GGEGVYAIARCCLLP	PCSK9	516	Q8NBP7
GRLFCVFYGLFGVPL	KCNK5	111	O95279
KGAYCRALVIAPLFG	SLC25A22	286	Q9H936
GKFRLRGLLPGCVYH	NOMO1	1001	Q15155
KYAIPCLIGISRAFG	PI4KA	181	P42356
GYYGLLFCPRGRLCQ	LMLN2	586	A0A1B0GTW7
RLPGVAGQYLFKCLI	METTL16	506	Q86W50
RYLAELCGVGAVLPG	TUBGCP6	471	Q96RT7
PRCLFGLGEALNSIY	KLHL40	401	Q2TBA0
GNTGVKFLCEGLRYP	NLRP2	881	Q9NX02
VGGLLISSGCALYPL	LHFPL1	126	Q86WI0
LLLGAAGHLYPGEVC	INSR	21	P06213
VLYGPLEGCLAPNGR	RALGAPA2	1476	Q2PPJ7
FLGGLLIGAGCALYP	LHFPL6	126	Q9Y693
NPVLYACAGGGLLRS	LTB4R	281	Q15722
VCFLPGTLALGVYHG	MAN1B1	526	Q9UKM7
APDFRAYLIGGLIAL	IL1RL2	331	Q9HB29
LLVRPAGALVEGLYC	DNAJC25	31	Q9H1X3
LRCRGPVDGVGLALY	IGSF1	341	Q8N6C5
AGGALLTLLLCVGPY	FFAR1	226	O14842
PYGAVGCRALPSIIL	C5AR2	101	Q9P296
LLNYCKGGIAFFRPG	CPLANE1	1241	Q9H799
GPGRLLLVCHVSGFY	CD1D	216	P15813
AFRQICPYGSGIIVG	FBN1	2106	P35555
YLGGACAFLVGPLVV	SLC49A4	191	Q96SL1
LPLFFCAGLAFIGLG	TMEM30B	36	Q3MIR4
GLCVGPELTALGSFY	BAHD1	366	Q8TBE0
QAGCSPVYRRGGFLL	LSMEM2	86	Q8N112
PRSGLAGCVVGGLLY	KEAP1	361	Q14145
YFGDPLGRNGPVRLC	LAMC1	811	P11047
PLFAREGGIYAVLVC	CUL9	766	Q8IWT3
FIACVVVLYRPGGGP	EML3	276	Q32P44
YRIGFGQCAGKVLPA	FAH	401	P16930
PLLFGCLGVFGLFRL	DHRS7B	26	Q6IAN0
IYLAGILVGAAACGP	SLC22A12	151	Q96S37
FLLGYSIPVGCVGLA	SLC15A3	226	Q8IY34
AIVCPLGAFGLQEYG	SLC15A5	171	A6NIM6
LGGLGERVLGFCQLY	ATP4A	556	P20648
LCAAFSVLPYGEGLR	CABLES2	186	Q9BTV7
RGLCNGLGPALYGFI	MFSD14B	386	Q5SR56
LGLRGCFGAARLLYP	MMAB	16	Q96EY8
FGPLLCRLSLYVGEG	MLNR	106	O43193
RLPGGGILTGRCVNY	P2RX3	126	P56373
ILCPFGLILGSYGRI	OR10C1	206	Q96KK4
NGGGLVTRLRYPVCF	ITK	326	Q08881
IGIISGLGYCFSFLP	SLC16A6	121	O15403
RLYGACLCDPGLYGR	MEGF6	621	O75095
GFAAVGLLFIYGCLP	SLC2A13	581	Q96QE2
LEPLGTLGYCGAVGL	VARS2	946	Q5ST30
FIRGPGAACGLTSLY	TRMT2B	266	Q96GJ1
GVLTGLGFALCYSPA	SLC16A12	146	Q6ZSM3
LGARGISLLGLYFGC	NXN	26	Q6DKJ4
GFIVAAGGLCIAYPF	TMEM178A	266	Q8NBL3
PGGNLFGIIILFYCA	SLC9B2	111	Q86UD5
GYLLGGLLIGFYVDP	SLCO5A1	316	Q9H2Y9
GLPGLFVACAYSGTL	SLC5A8	336	Q8N695
LLCGLPFGILGALIY	MRGPRX4	226	Q96LA9
PLALDLGCGRGYIAQ	NDUFAF5	91	Q5TEU4
LGRGYVCLCPLGYTG	SVEP1	1211	Q4LDE5
CRGDGLKVFVYPAVG	EXTL1	91	Q92935
ALYSFCREAGLPGLL	STK36	491	Q9NRP7
LLGFAGPLCIFGIVD	ABCC8	311	Q09428
GGVLYLFCGLLALVP	CLDN5	121	O00501
LPSVGYCVLLTFGFG	TMTC4	416	Q5T4D3
VRLPDGCLLQGTFYA	UBXN6	341	Q9BZV1
CGAVFRKYPIDLAGL	THOC2	646	Q8NI27
GLRGAICFALVFLLP	SLC9A2	436	Q9UBY0
CFGIGLALAGYVRPL	PRAF2	51	O60831
GVLYGALDCGRPDSL	VPS18	291	Q9P253
PIFGFLLGSLCAKLY	SLCO1C1	236	Q9NYB5
CLVAAAPYGGPIALL	VPS16	36	Q9H269
CLALEGVRTPVLFGY	TCTN1	421	Q2MV58
CVALLLPGAPARGYT	VWCE	11	Q96DN2
LGYPALGLLKFCTVG	TM2D1	141	Q9BX74
LGYVVLCLLGAGPLE	TRBV27	6	A0A0K0K1C4
AGVLGLGACVLSSPY	PSME4	1761	Q14997
GFCASRPGLLFLGLL	PF4	6	P02776
IAIRGYGLFAGPCKV	PRKDC	361	P78527
LLGRCVGFGNYRPFL	ZDHHC24	126	Q6UX98
LLGAGGPLLYGLYCL	TMEM245	151	Q9H330
PLLRCLVLTGFGGYD	VAT1	46	Q99536
VPALGTLGCYRFLFN	nan	6	Q5PR19
LLGVGCRLTPGLYHL	TRPM4	876	Q8TD43
AFPKRILRGYGNCGL	ZNF195	166	O14628
PPYRGLLCAVLGVGA	TM9SF1	301	O15321
PFGSIAYRVNLLCGL	TMEM260	86	Q9NX78
SLFPGERLVGYGIVC	VWA5B1	561	Q5TIE3
RVAPLRPGFALCGYA	nan	91	Q8N402
GLAAPDIGVYRCIAG	ADAMTSL3	971	P82987