Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	endopeptidase activity	USP34 TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 CFLAR PRSS53 ADAMTS9 CTSZ CAPN15	7.78e-06	430	116	12	GO:0004175
GeneOntologyMolecularFunction	PLC activating G protein-coupled glutamate receptor activity	GRM1 GRM5	3.35e-05	2	116	2	GO:0001639
GeneOntologyMolecularFunction	serine-type endopeptidase activity	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	1.23e-04	190	116	7	GO:0004252
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	GRM1 GRM5	1.99e-04	4	116	2	GO:0099583
GeneOntologyMolecularFunction	serine-type peptidase activity	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	2.09e-04	207	116	7	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	2.41e-04	212	116	7	GO:0017171
GeneOntologyMolecularFunction	G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential	GRM1 GRM5	3.31e-04	5	116	2	GO:0099530
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	MYCBP2 PLEKHG4 RAPGEF4 TIAM2 PLEKHG4B HERC1 FGD6	4.06e-04	231	116	7	GO:0005085
GeneOntologyMolecularFunction	peptidase activity	USP34 TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 CFLAR PRSS53 ADAMTS9 CTSZ CAPN15	4.24e-04	654	116	12	GO:0008233
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM1 GRM5	1.17e-03	9	116	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM1 GRM5	1.17e-03	9	116	2	GO:0001640
Domain	TRYPSIN_HIS	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	3.60e-06	103	116	7	IPR018114
Domain	TRYPSIN_SER	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	4.36e-06	106	116	7	PS00135
Domain	TRYPSIN_HIS	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	4.64e-06	107	116	7	PS00134
Domain	Peptidase_S1A	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	6.67e-06	113	116	7	IPR001314
Domain	TRYPSIN_DOM	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	7.49e-06	115	116	7	PS50240
Domain	Tryp_SPc	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	8.39e-06	117	116	7	SM00020
Domain	Trypsin_dom	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	1.05e-05	121	116	7	IPR001254
Domain	Trypsin	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	1.05e-05	121	116	7	PF00089
Domain	Peptidase_S1_PA	TMPRSS9 PRSS57 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	1.17e-05	123	116	7	IPR009003
Domain	TRYPSIN_SER	TMPRSS9 PRSS12 ACR TMPRSS11E PRSS22 PRSS53	2.05e-05	90	116	6	IPR033116
Domain	GluR_Homer-bdg	GRM1 GRM5	3.82e-05	2	116	2	PF10606
Domain	Metabotropic_Glu_rcpt_Homer-bd	GRM1 GRM5	3.82e-05	2	116	2	IPR019588
Domain	GPCR_3_mtglu_rcpt_1	GRM1 GRM5	3.82e-05	2	116	2	IPR001256
Domain	GluR_Homer-bdg	GRM1 GRM5	3.82e-05	2	116	2	SM01229
Domain	GPCR_3_mtglu_rcpt_5	GRM1 GRM5	3.82e-05	2	116	2	IPR000202
Domain	NCD3G	TAS1R3 GRM1 GRM5	6.38e-05	13	116	3	PF07562
Domain	GPCR_3_9-Cys_dom	TAS1R3 GRM1 GRM5	6.38e-05	13	116	3	IPR011500
Domain	GPCR_3_CS	TAS1R3 GRM1 GRM5	8.08e-05	14	116	3	IPR017979
Domain	C_TYPE_LECTIN_1	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	1.41e-04	80	116	5	PS00615
Domain	Lectin_C	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	1.77e-04	84	116	5	PF00059
Domain	CLECT	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	1.77e-04	84	116	5	SM00034
Domain	C_TYPE_LECTIN_2	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	1.87e-04	85	116	5	PS50041
Domain	C-type_lectin-like	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	1.98e-04	86	116	5	IPR001304
Domain	-	KLHL6 ATRN LCMT2 ATRNL1	2.23e-04	48	116	4	2.120.10.80
Domain	TM_Fragile-X-F-assoc	TMEM185B TMEM185A	2.28e-04	4	116	2	IPR019396
Domain	Tmemb_185A	TMEM185B TMEM185A	2.28e-04	4	116	2	PF10269
Domain	GPCR_3	TAS1R3 GRM1 GRM5	2.86e-04	21	116	3	IPR000337
Domain	7tm_3	TAS1R3 GRM1 GRM5	3.30e-04	22	116	3	PF00003
Domain	G_PROTEIN_RECEP_F3_2	TAS1R3 GRM1 GRM5	3.30e-04	22	116	3	PS00980
Domain	G_PROTEIN_RECEP_F3_3	TAS1R3 GRM1 GRM5	3.30e-04	22	116	3	PS00981
Domain	G_PROTEIN_RECEP_F3_1	TAS1R3 GRM1 GRM5	3.30e-04	22	116	3	PS00979
Domain	G_PROTEIN_RECEP_F3_4	TAS1R3 GRM1 GRM5	3.30e-04	22	116	3	PS50259
Domain	GPCR_3_C	TAS1R3 GRM1 GRM5	3.30e-04	22	116	3	IPR017978
Domain	-	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	3.47e-04	97	116	5	3.10.100.10
Domain	Kelch-typ_b-propeller	KLHL6 ATRN LCMT2 ATRNL1	3.77e-04	55	116	4	IPR015915
Domain	C-type_lectin-like/link	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	3.81e-04	99	116	5	IPR016186
Domain	CTDL_fold	ATRN PKD1L2 MRC2 ATRNL1 KLRG1	5.44e-04	107	116	5	IPR016187
Domain	RhoGEF	PLEKHG4 TIAM2 PLEKHG4B FGD6	8.47e-04	68	116	4	SM00325
Domain	RhoGEF	PLEKHG4 TIAM2 PLEKHG4B FGD6	9.45e-04	70	116	4	PF00621
Domain	DH_2	PLEKHG4 TIAM2 PLEKHG4B FGD6	9.45e-04	70	116	4	PS50010
Domain	-	PLEKHG4 TIAM2 PLEKHG4B FGD6	9.96e-04	71	116	4	1.20.900.10
Domain	DH-domain	PLEKHG4 TIAM2 PLEKHG4B FGD6	9.96e-04	71	116	4	IPR000219
Domain	GPCR_3_mtglu_rcpt	GRM1 GRM5	1.04e-03	8	116	2	IPR000162
Domain	WD40	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	1.17e-03	259	116	7	PF00400
Domain	WD40	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	1.43e-03	268	116	7	SM00320
Domain	ANF_lig-bd_rcpt	TAS1R3 GRM1 GRM5	1.56e-03	37	116	3	IPR001828
Domain	ANF_receptor	TAS1R3 GRM1 GRM5	1.56e-03	37	116	3	PF01094
Domain	WD40_repeat	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	1.56e-03	272	116	7	IPR001680
Domain	WD_REPEATS_1	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	1.76e-03	278	116	7	PS00678
Domain	WD_REPEATS_2	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	1.80e-03	279	116	7	PS50082
Domain	WD_REPEATS_REGION	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	1.80e-03	279	116	7	PS50294
Domain	Peripla_BP_I	TAS1R3 GRM1 GRM5	1.81e-03	39	116	3	IPR028082
Domain	Kelch_2	LCMT2 ATRNL1	2.85e-03	13	116	2	IPR011498
Domain	Kelch_2	LCMT2 ATRNL1	2.85e-03	13	116	2	PF07646
Domain	CUB	ATRN ADGRB3 ATRNL1	4.36e-03	53	116	3	PS01180
Domain	-	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	4.78e-03	333	116	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	4.94e-03	335	116	7	IPR015943
Domain	CUB_dom	ATRN ADGRB3 ATRNL1	5.35e-03	57	116	3	IPR000859
Domain	Gal_Oxase/kelch_b-propeller	KLHL6 ATRN LCMT2	5.89e-03	59	116	3	IPR011043
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	USP34 MYCBP2 BCAS3 POLE TBC1D9 TIAM2 DIP2A FASN MROH6 PLEKHM2 HERC1 ABTB2 CTSZ RAI1 SMG6	4.74e-06	1105	117	15	35748872
Pubmed	Involvement of group I metabotropic glutamate receptors and glutamate transporters in the slow excitatory synaptic transmission in the spinal cord dorsal horn.	GRM1 GRM5	1.12e-05	2	117	2	18554818
Pubmed	Cyclic ADP ribose-dependent Ca2+ release by group I metabotropic glutamate receptors in acutely dissociated rat hippocampal neurons.	GRM1 GRM5	1.12e-05	2	117	2	22028929
Pubmed	Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.	GRM1 GRM5	1.12e-05	2	117	2	9185557
Pubmed	Morphological changes and spatial regulation of diacylglycerol kinase-zeta, syntrophins, and Rac1 during myoblast fusion.	DGKZ SNTB2	1.12e-05	2	117	2	17410543
Pubmed	Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.	GRM1 GRM5	1.12e-05	2	117	2	27392515
Pubmed	Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia.	GRM1 GRM5	1.12e-05	2	117	2	28982591
Pubmed	A novel gene, FAM11A, associated with the FRAXF CpG island is transcriptionally silent in FRAXF full mutation.	TMEM185B TMEM185A	1.12e-05	2	117	2	12404111
Pubmed	mGluR₁,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice.	GRM1 GRM5	1.12e-05	2	117	2	22681774
Pubmed	Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus.	GRM1 GRM5	1.12e-05	2	117	2	18035501
Pubmed	Determination of group I metabotropic glutamate receptor subtypes involved in the frequency of epileptiform activity in vitro using mGluR1 and mGluR5 mutant mice.	GRM1 GRM5	1.12e-05	2	117	2	12623213
Pubmed	Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition.	TAS1R3 GRM5	1.12e-05	2	117	2	24497581
Pubmed	Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation.	GRM1 GRM5	1.12e-05	2	117	2	15184389
Pubmed	mGluR1,5 activation protects cortical astrocytes and GABAergic neurons from ischemia-induced impairment.	GRM1 GRM5	1.12e-05	2	117	2	23280324
Pubmed	Metabotropic glutamate receptors in the main olfactory bulb drive granule cell-mediated inhibition.	GRM1 GRM5	1.12e-05	2	117	2	17093122
Pubmed	Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.	GRM1 GRM5	1.12e-05	2	117	2	11591458
Pubmed	Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.	GRM1 GRM5	1.12e-05	2	117	2	33279506
Pubmed	In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis.	GRM1 GRM5	1.12e-05	2	117	2	31102766
Pubmed	Genetic analysis of attractin homologs.	ATRN ATRNL1	1.12e-05	2	117	2	18064672
Pubmed	mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning.	GRM1 GRM5	1.12e-05	2	117	2	35805089
Pubmed	Corticostriatal LTP requires combined mGluR1 and mGluR5 activation.	GRM1 GRM5	1.12e-05	2	117	2	12559117
Pubmed	Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression.	GRM1 GRM5	1.12e-05	2	117	2	31540330
Pubmed	Differential distribution of group I metabotropic glutamate receptors in developing human cortex.	GRM1 GRM5	1.12e-05	2	117	2	20149785
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF493 ZNF254 ZNF91	1.64e-05	15	117	3	15885501
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	GALNT15 RMND5B PRSS57 RTN4R TMPRSS11E PRSS22 KIRREL2 PRSS53 SUSD1 SIGIRR CD163L1 LRRN2 NXPH3	2.85e-05	985	117	13	12975309
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN USP34 ADGRB3 LCMT2 ATRNL1	2.92e-05	105	117	5	9628581
Pubmed	Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling.	GRM1 GRM5	3.36e-05	3	117	2	19717561
Pubmed	Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.	GRM1 GRM5	3.36e-05	3	117	2	12364493
Pubmed	SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5.	GRM1 GRM5	3.36e-05	3	117	2	31270711
Pubmed	Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome.	GRM1 GRM5	3.36e-05	3	117	2	20410124
Pubmed	PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes.	RSBN1 PHTF1	3.36e-05	3	117	2	18305142
Pubmed	The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors.	GRM1 GRM5	3.36e-05	3	117	2	16024054
Pubmed	Cellular FLIP long isoform (cFLIPL)-IKKα interactions inhibit IRF7 activation, representing a new cellular strategy to inhibit IFNα expression.	CHUK CFLAR	3.36e-05	3	117	2	29222334
Pubmed	Nonsynonymous single nucleotide polymorphisms in human tas1r1, tas1r3, and mGluR1 and individual taste sensitivity to glutamate.	TAS1R3 GRM1	3.36e-05	3	117	2	19571223
Pubmed	Selective inhibition of IkappaB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level.	CHUK CFLAR	3.36e-05	3	117	2	17237443
Pubmed	Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages.	CFLAR PIK3CG	3.36e-05	3	117	2	19339247
Pubmed	mGluR1 and mGluR5 Synergistically Control Cholinergic Synaptic Transmission in the Thalamic Reticular Nucleus.	GRM1 GRM5	3.36e-05	3	117	2	27466334
Pubmed	Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome.	GRM1 GRM5	3.36e-05	3	117	2	21571007
Pubmed	Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.	GRM1 GRM5	3.36e-05	3	117	2	20534533
Pubmed	Metabotropic glutamate receptors 1 and 5 differentially regulate bulbar dopaminergic cell function.	GRM1 GRM5	3.36e-05	3	117	2	20692242
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	RMND5B ZNF493 ZNF678 ZNF611 ZNF74 ZNF91	3.54e-05	181	117	6	37372979
Pubmed	Transcriptome profiling of mouse brain and lung under Dip2a regulation using RNA-sequencing.	PRSS22 DIP2A BMPR2	4.06e-05	20	117	3	31291246
Pubmed	Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system.	GRM1 GRM5	6.70e-05	4	117	2	29079293
Pubmed	Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons.	GRM1 GRM5	6.70e-05	4	117	2	15745950
Pubmed	Crosstalk between ILC2s and Th2 cells varies among mouse models.	CRLF2 KLRG1	6.70e-05	4	117	2	36735533
Pubmed	Antioxidant c-FLIP inhibits Fas ligand-induced NF-kappaB activation in a phosphatidylinositol 3-kinase/Akt-dependent manner.	CFLAR PIK3CG	6.70e-05	4	117	2	21856935
Pubmed	Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.	GRM1 GRM5	6.70e-05	4	117	2	20876210
Pubmed	Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.	GRM1 GRM5	6.70e-05	4	117	2	15254091
Pubmed	Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR.	GRM1 GRM5	6.70e-05	4	117	2	18094233
Pubmed	Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?	GRM1 GRM5	6.70e-05	4	117	2	21605597
Pubmed	A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia.	RAPGEF4 TIAM2	1.11e-04	5	117	2	9789079
Pubmed	Genetic and phenotypic studies of the dark-like mutant mouse.	ATRN ATRNL1	1.11e-04	5	117	2	18821597
Pubmed	Umami taste in mice uses multiple receptors and transduction pathways.	TAS1R3 GRM1	1.11e-04	5	117	2	22183726
Pubmed	Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor.	TMEM185B TMEM185A	1.11e-04	5	117	2	15525354
Pubmed	Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB.	GRM5 CHUK	1.11e-04	5	117	2	18541671
Pubmed	Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.	INPP1 CFLAR	1.11e-04	5	117	2	9729047
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF493 ZNF254 ZNF91	1.27e-04	29	117	3	14563677
Pubmed	A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization.	GRM1 GRM5	1.67e-04	6	117	2	23911326
Pubmed	Homer: a protein that selectively binds metabotropic glutamate receptors.	GRM1 GRM5	1.67e-04	6	117	2	9069287
Pubmed	Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer.	GRM1 GRM5	1.67e-04	6	117	2	11418862
Pubmed	IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.	CHUK PIK3CG	1.67e-04	6	117	2	20671123
Pubmed	HIV-1 Tat interaction with cyclin T1 represses mannose receptor and the bone morphogenetic protein receptor-2 transcription.	BMPR2 MRC2	1.67e-04	6	117	2	16615932
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	GRWD1 BCAS3 WDR81 DGKZ CHUK AP4E1 MROH6 WRAP73 FAM53B CDC25B ABTB2 SNTB2	2.03e-04	1038	117	12	26673895
Pubmed	High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer.	CHUK CFLAR	2.33e-04	7	117	2	19728335
Pubmed	Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy.	GRM1 GRM5	2.33e-04	7	117	2	25003238
Pubmed	The mouse mahogany locus encodes a transmembrane form of human attractin.	ATRN CDC25B	2.33e-04	7	117	2	10086356
Pubmed	The human herpes virus 8-encoded viral FLICE inhibitory protein physically associates with and persistently activates the Ikappa B kinase complex.	CHUK CFLAR	2.33e-04	7	117	2	11830587
Pubmed	An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis.	CHUK CFLAR	2.33e-04	7	117	2	11940602
Pubmed	Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.	GRM1 GRM5	2.33e-04	7	117	2	9920659
Pubmed	Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions.	DGKZ SNTB2	2.33e-04	7	117	2	11352924
Pubmed	Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins.	GRM1 GRM5	2.33e-04	7	117	2	9808458
Pubmed	Galnt1 is required for normal heart valve development and cardiac function.	GALNT15 BMPR2 ADAMTS9	2.44e-04	36	117	3	25615642
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KLHL6 USP34 GRWD1 ZNF254 DHDDS DGKZ LCMT2 TIAM2 MED24 SLC38A2 ATRNL1 HERC1	3.01e-04	1084	117	12	11544199
Pubmed	Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.	GRM1 GRM5	3.10e-04	8	117	2	11850456
Pubmed	GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain.	GRM1 GRM5	3.10e-04	8	117	2	9651375
Pubmed	TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.	MYCBP2 DGKZ GRM1 CFLAR FASN MB21D2 ADAMTS9	3.22e-04	382	117	7	37249651
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	ATRN COL27A1 WDR38 ALG5	3.72e-04	100	117	4	26073538
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 ADGRB3 TIAM2 SLC38A2 MRC2 FAM53B RAI1 SMG6	4.35e-04	529	117	8	14621295
Pubmed	Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.	GRM1 GRM5	4.96e-04	10	117	2	9069281
Pubmed	The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.	TAS1R3 GRM1	4.96e-04	10	117	2	17156446
Pubmed	Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.	TAS1R3 PKD1L2	4.96e-04	10	117	2	16805797
Pubmed	Functional analysis of the SRY-KRAB interaction in mouse sex determination.	ZNF493 ZNF91	4.96e-04	10	117	2	18588511
Pubmed	Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.	ZNF493 ZNF91	6.05e-04	11	117	2	15469996
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TNK1 MYCBP2 BCAS3 MATK SLC38A2 BMPR2 FAM53B CDC25B FGD6 ABTB2	6.76e-04	861	117	10	36931259
Pubmed	Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.	TMPRSS11E GRM5	7.24e-04	12	117	2	23227193
Pubmed	Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.	ZNF493 ZNF91	8.54e-04	13	117	2	19850934
Pubmed	Developmental changes in human fetal testicular cell numbers and messenger ribonucleic acid levels during the second trimester.	WNT2B MAMLD1	8.54e-04	13	117	2	17848411
Pubmed	Functional genomic landscape of cancer-intrinsic evasion of killing by T cells.	GRWD1 CHUK CFLAR MED24 AP4E1 ALG5 SLC30A9	9.27e-04	457	117	7	32968282
Pubmed	A mouse knockout library for secreted and transmembrane proteins.	PRSS57 RTN4R PRSS22 KIRREL2 SUSD1 SIGIRR LRRN2	9.62e-04	460	117	7	20562862
Pubmed	Differential signaling mechanism for HIV-1 Nef-mediated production of IL-6 and IL-8 in human astrocytes.	CHUK PIK3CG	9.94e-04	14	117	2	26075907
Pubmed	Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.	GRM1 GRM5	9.94e-04	14	117	2	21795692
Pubmed	Activation of the NF-kappaB pathway by caspase 8 and its homologs.	CHUK CFLAR	1.14e-03	15	117	2	11002417
Pubmed	Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor.	GRM1 GRM5	1.14e-03	15	117	2	22241839
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	MYCBP2 BCAS3 ADGRB3 BMPR2 MB21D2 SNTB2	1.17e-03	347	117	6	17114649
Pubmed	Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice.	GRM1 GRM5	1.31e-03	16	117	2	30466882
Pubmed	The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma.	MED24 DNAH11	1.48e-03	17	117	2	23502783
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	KLHL6 TNK1 FBXL8 MATK INSRR ZNF74	1.66e-03	372	117	6	22939624
Pubmed	The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.	ACR TDRD1	2.05e-03	20	117	2	20059948
Pubmed	Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.	MTPAP SLC38A2 ALG5 SNTB2	2.14e-03	160	117	4	31678930
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	MYCBP2 POLE CHUK SLC38A2 RSBN1 NOP9 PIP4P1	2.22e-03	533	117	7	25544563
Interaction	PLEKHG7 interactions	USP34 PLEKHG4 BCAS3 POLE WDR81 CHUK MROH6 SNTB2	1.93e-06	150	112	8	int:PLEKHG7
Cytoband	2q33-q34	CFLAR BMPR2	2.29e-04	9	117	2	2q33-q34
GeneFamily	Proteases, serine	TMPRSS9 PRSS57 PRSS12 TMPRSS11E PRSS22 PRSS53	4.95e-07	63	85	6	738
GeneFamily	WD repeat domain containing	GRWD1 BCAS3 EML6 WDR81 WDR38 WRAP73 HERC1	2.34e-04	262	85	7	362
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM1 GRM5	6.00e-04	8	85	2	281
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ATRN PKD1L2 ATRNL1	9.40e-04	41	85	3	1298
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG4 TIAM2 PLEKHG4B PLEKHM2 FGD6	2.87e-03	206	85	5	682
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG4 TIAM2 FGD6	3.71e-03	66	85	3	722
GeneFamily	F-box and leucine rich repeat proteins	FBXL8 FBXL21P	4.33e-03	21	85	2	558
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZNF527 KIRREL2 MTPAP NOP9 MB21D2 FAM53B ABTB2 PHTF1	5.97e-08	200	117	8	be83f442179ba4217d12f0458059586ff3130991
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Slc17a7.Cplx3_(Cortical_subplate)--\|Striatum / BrainAtlas - Mouse McCarroll V32	PRSS57 PLEKHG4 PRSS12 PRSS22 PRSS53 NXPH3	3.35e-07	104	117	6	7642c6ac1a51b431a8d48d35520930c072a3710e
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Slc17a7.Cplx3_(Cortical_subplate)\|Striatum / BrainAtlas - Mouse McCarroll V32	PRSS57 PLEKHG4 PRSS12 PRSS22 PRSS53 NXPH3	3.35e-07	104	117	6	59e982b521610af0532c63b2caf934fa65644b0b
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Slc17a7.Cplx3_(Cortical_subplate)-\|Striatum / BrainAtlas - Mouse McCarroll V32	PRSS57 PLEKHG4 PRSS12 PRSS22 PRSS53 NXPH3	3.35e-07	104	117	6	016704f1d1c43e6d4067ad1d81c22cc660e605d0
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TNK1 TMPRSS9 PRSS22 CHUK PLEKHG4B AP4E1	3.73e-06	157	117	6	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK COL27A1 PRSS22 PIK3CG CREG2	5.50e-06	168	117	6	8072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell	3'-Child09-12-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK PRSS22 PIK3CG LRRN2 CREG2	5.69e-06	169	117	6	05e12524d68d409fed386ffad233305683b4575b
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSRR SLC38A2 PRSS53 ACOT11 SLC35D3 HERC1	6.73e-06	174	117	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSRR HEATR6 PRSS53 ACOT11 SLC35D3 HERC1	7.66e-06	178	117	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK COL27A1 PRSS22 PIK3CG CREG2	9.55e-06	185	117	6	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	3'_v3-bone_marrow\|World / Manually curated celltypes from each tissue	PRSS57 MATK DGKZ CFLAR DIP2A KLRG1	1.14e-05	191	117	6	7b759831f1b1c8575c31f67d0d9eb11c6a833cf3
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK COL27A1 PRSS22 PIK3CG CREG2	1.14e-05	191	117	6	54f07e4de61735051498846afb44b1798bed8144
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	MAMLD1 C5AR2 TBC1D9 MB21D2 CD163L1 CTSZ	1.44e-05	199	117	6	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	Neuronal-Excitatory-eF(C1QL3)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL27A1 GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.49e-05	200	117	6	7668ae7ed550583ab59e419c5c9bb9f2d7e8e0d5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Mesoderm\|10w / Sample Type, Dataset, Time_group, and Cell type.	WDR81 CHUK PLEKHG4B CD163L1 WRAP73 SNTB2	1.49e-05	200	117	6	9ef226ebb0a7cdb9431e2fa65faa2a7d67da590d
ToppCell	Neuronal-Excitatory-eF(C1QL3)----L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL27A1 GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.49e-05	200	117	6	44f0278cb0e4ffcda4af3719d7f5819a10929b9f
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	MYCBP2 EML6 RAPGEF4 GRM5 ATRNL1 HERC1	1.49e-05	200	117	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Neuronal-Excitatory-eF(C1QL3)---\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL27A1 GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.49e-05	200	117	6	23da7790e09575b2ca909ed16806b44223bf1017
ToppCell	Neuronal-Excitatory-eF(C1QL3)-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL27A1 GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.49e-05	200	117	6	91f3df1c5a661ff703835f58a35cee93f18eb15c
ToppCell	Neuronal-Excitatory-eF(C1QL3)--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL27A1 GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.49e-05	200	117	6	2e2b1d252972b702ade25526ec8461bf613d81b0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT15 TMPRSS11E RAPGEF4 PIK3CG CDC25B	3.93e-05	144	117	5	f501e11b1d051ca67124137017a79a2d5bb6ae87
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAS1R3 C5AR2 GRM1 PIK3CG TMEM270	6.12e-05	158	117	5	d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAS1R3 C5AR2 GRM1 PIK3CG TMEM270	6.12e-05	158	117	5	ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PRSS12 RTN4R PRSS22 TIAM2 CREG2	6.69e-05	161	117	5	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK COL27A1 PRSS22 PIK3CG	6.89e-05	162	117	5	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TMEM185B MATK MB21D2 PIK3CG CD163L1	8.18e-05	168	117	5	8459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCell	droplet-Fat-Bat-18m\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN PLEKHG4 FBXL8 FETUB PRSS53	8.65e-05	170	117	5	c720d81bc29a8fd1f1249c6af408471d561f1d5d
ToppCell	droplet-Fat-Bat\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN PLEKHG4 FBXL8 FETUB PRSS53	8.65e-05	170	117	5	c4ecdfc2b4710da0a5fbb20e9df02536023badb1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL27A1 MAMLD1 FASN MRC2 ATRNL1	8.89e-05	171	117	5	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL27A1 MAMLD1 FASN MRC2 ATRNL1	8.89e-05	171	117	5	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	10x3'2.3-week_17-19-Lymphocytic_T-T_NK-CD8_T_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PLEKHG4 MATK C1orf74 LRRN2 KLRG1	9.64e-05	174	117	5	fee2ee3e888ce71f9f3f05d7dc8aaa9549480205
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.02e-04	176	117	5	0710689e66deba179b0a8038cdd56b4834984f12
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATK COL27A1 SUSD1 PIK3CG CD163L1	1.02e-04	176	117	5	3d372c1d527fcc118d1e5809f2524fc387682472
ToppCell	facs-Skin-Telogen-3m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATK COL27A1 SUSD1 PIK3CG CD163L1	1.02e-04	176	117	5	7b3f3d9b33770edf294cee0eccaf8a46f9331461
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 GRM5 ADAMTS9 MRC2 DNAH11	1.02e-04	176	117	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	facs-Skin-Telogen-3m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATK COL27A1 SUSD1 PIK3CG CD163L1	1.02e-04	176	117	5	9c0fb2c6ae84febdf7c3d4e648985f597dcffe7a
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 POLE PRSS22 FASN B4GALNT3	1.05e-04	177	117	5	ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL27A1 MAMLD1 KLRG1 CTSZ DNAH11	1.05e-04	177	117	5	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-ILC2\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 PRSS57 FBXL8 CRLF2 PIK3CG	1.05e-04	177	117	5	9828504591599619649d41a78daf7c052729c669
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL27A1 MAMLD1 KLRG1 CTSZ DNAH11	1.05e-04	177	117	5	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	368C-Epithelial_cells-Epithelial-B_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ABCA3 POLE PRSS22 FASN B4GALNT3	1.05e-04	177	117	5	d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK COL27A1 PRSS22 CREG2	1.07e-04	178	117	5	f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.07e-04	178	117	5	6f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCell	3'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA3 FBXL8 KNSTRN PRSS53 CDC25B	1.10e-04	179	117	5	2285e3a9018a60d7f6e974fee46b6f61d39aa76f
ToppCell	3'-Adult-Appendix-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA3 FBXL8 KNSTRN PRSS53 CDC25B	1.10e-04	179	117	5	0b0f27d7c5cc5ae7618d887dcfa7219df8ff1935
ToppCell	3'-Adult-Appendix-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA3 FBXL8 KNSTRN PRSS53 CDC25B	1.10e-04	179	117	5	63bc819df62b1f8f37bf1f17bdd4fcc161886923
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 TBC1D9 SUSD1 B4GALNT3 ABTB2	1.13e-04	180	117	5	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL27A1 ADGRB3 ADAMTS9 MRC2 ATRNL1	1.19e-04	182	117	5	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRM1 CFLAR PIK3CG B4GALNT3 SNTB2	1.25e-04	184	117	5	9a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RTN4R YIPF7 C1orf74 CRLF2 ZNF74	1.25e-04	184	117	5	b8ecf58b3bdb25bcba5efc2d764930bb84ab95c8
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RTN4R YIPF7 C1orf74 CRLF2 ZNF74	1.25e-04	184	117	5	b232a9cc1d14e1a134b037016d437b93921a4a0f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 TBC1D9 PLEKHG4B SUSD1 ABTB2	1.29e-04	185	117	5	d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FBXL8 POLE COL27A1 NOP9 CCDC183	1.29e-04	185	117	5	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	PRSS57 MATK CFLAR DIP2A KLRG1	1.29e-04	185	117	5	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRSS22 TBC1D9 LRRN2 B4GALNT3 ABTB2	1.32e-04	186	117	5	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D9 SUSD1 LRRN2 B4GALNT3 ABTB2	1.32e-04	186	117	5	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	INPP1 WNT2B BMPR2 ADAMTS9 SNTB2	1.35e-04	187	117	5	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 PRSS12 DHDDS LCMT2 SMG6	1.35e-04	187	117	5	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLHL6 PRSS12 DHDDS LCMT2 SMG6	1.35e-04	187	117	5	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D9 SUSD1 LRRN2 B4GALNT3 ABTB2	1.39e-04	188	117	5	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EML6 TBC1D9 SUSD1 B4GALNT3 ABTB2	1.42e-04	189	117	5	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D9 SUSD1 LRRN2 B4GALNT3 ABTB2	1.42e-04	189	117	5	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TBC1D9 SUSD1 ADAMTS9 B4GALNT3 ABTB2	1.46e-04	190	117	5	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TAS1R3 MATK COL27A1 PRSS22 CREG2	1.53e-04	192	117	5	d6ea34391c3f730684b82e912d9cf55e928b3311
ToppCell	nucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-SVEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GALNT15 RAPGEF4 BMPR2 ADAMTS9 SNTB2	1.53e-04	192	117	5	c3dda7c48732b0b8bde36de282d64192f5e9b98f
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	INPP1 WNT2B BMPR2 ADAMTS9 SNTB2	1.60e-04	194	117	5	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT15 WNT2B RAPGEF4 ADGRB3 BMPR2	1.60e-04	194	117	5	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	(1)_T_CD8_CTL\|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MATK DGKZ SIGIRR CDC25B KLRG1	1.64e-04	195	117	5	f582b854e5a4c52764aad5abe4e28ea77a7445f7
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MATK PRSS22 B3GNT8 B4GALNT3 KLRG1	1.64e-04	195	117	5	c7b54b210cc2c8ddaefebfba74381adb2ca698b8
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MATK PRSS22 B3GNT8 B4GALNT3 KLRG1	1.64e-04	195	117	5	e173a713d273b135db4f71bdcaada3b0e55d74f1
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MATK PRSS22 B3GNT8 B4GALNT3 KLRG1	1.64e-04	195	117	5	59164d115a0928cc9b79c7661c7190ad695f9d80
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 RAPGEF4 INSRR PRSS53 HERC1	1.64e-04	195	117	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 RAPGEF4 INSRR PRSS53 HERC1	1.64e-04	195	117	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	PBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MATK PRSS22 B3GNT8 B4GALNT3 KLRG1	1.64e-04	195	117	5	a8fd42ff6c2bd80d0e3f20fe3bbf7d113b399df1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EML6 RAPGEF4 ADGRB3 GRM5 ATRNL1	1.68e-04	196	117	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	MATK DIP2A SIGIRR CDC25B KLRG1	1.72e-04	197	117	5	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL27A1 EML6 MAMLD1 MRC2 ATRNL1	1.72e-04	197	117	5	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PRSS12 ACR PLEKHG4B WDR38 DNAH11	1.72e-04	197	117	5	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL27A1 EML6 MAMLD1 MRC2 ATRNL1	1.72e-04	197	117	5	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	control-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MATK RTN4R B3GNT8 B4GALNT3 KLRG1	1.76e-04	198	117	5	13955a4026c97e11d94973ac87bf018f64a2616c
ToppCell	Parenchyma_COVID-19-Immune-TX-MoAM-4\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	MATK COL27A1 CD163L1 CREG2 CTSZ	1.76e-04	198	117	5	a7eed9eeb728a8796e2780090cc244856efd8c65
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RAPGEF4 GRM5 ATRNL1 HERC1 PHTF1	1.76e-04	198	117	5	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	COPD-Myeloid-Macrophage\|Myeloid / Disease state, Lineage and Cell class	MAMLD1 C5AR2 TBC1D9 MB21D2 CD163L1	1.81e-04	199	117	5	1cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac\|GI_small-bowel / Manually curated celltypes from each tissue	C5AR2 TBC1D9 MRC2 CD163L1 CTSZ	1.81e-04	199	117	5	8990a3d69e24cb3aaba9d6def3d0be9ee973436d
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Intestinal_macrophages\|GI_small-bowel / Manually curated celltypes from each tissue	C5AR2 TBC1D9 MRC2 CD163L1 CTSZ	1.81e-04	199	117	5	96070b5ffcbab4952970f43b536969ddd2ca5d14
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRSS22 TBC1D9 ADAMTS9 LRRN2 B4GALNT3	1.81e-04	199	117	5	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 RAPGEF4 DGKZ BMPR2 FGD6	1.85e-04	200	117	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 C5AR2 MB21D2 CD163L1 CTSZ	1.85e-04	200	117	5	ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCell	Control-Control-Lymphocyte-T/NK-MAIT\|Control / Disease, condition lineage and cell class	MATK PRSS22 B3GNT8 B4GALNT3 KLRG1	1.85e-04	200	117	5	888a8045e0457cd9d0c570360cca20a6efb44f13
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSRR PRSS53 ACOT11 SLC35D3	1.96e-04	109	117	4	0d4128af237afcc0adb4dfdd206fa3ddbe5b0e86
Computational	Neighborhood of EPHA7	RPGRIP1 ADGRB3 LCMT2 AP4E1 BMPR2 ATRNL1 PHTF1	1.75e-05	139	64	7	MORF_EPHA7
Computational	Neighborhood of FRK	RPGRIP1 ADGRB3 LCMT2 AP4E1 ATRNL1 PHTF1	4.64e-05	110	64	6	MORF_FRK
Computational	Neighborhood of DCC	RPGRIP1 ADGRB3 LCMT2 AP4E1 BMPR2 ATRNL1	5.13e-05	112	64	6	MORF_DCC
Drug	Ramipril [87333-19-5]; Down 200; 9.6uM; MCF7; HT_HG-U133A	USB1 MATK ADCK2 TDRD1 CFLAR AP4E1 PLEKHM2 CAPN15 SMG6	8.36e-07	197	117	9	3572_DN
Disease	primary aldosteronism	WNT2B EML6 ADGRB3 CCKAR	2.86e-06	26	113	4	MONDO_0001422
Disease	juvenile idiopathic arthritis	INPP1 RSBN1 FASN PHTF1	1.91e-04	74	113	4	EFO_0002609
Disease	response to angiotensin receptor blocker	BCAS3 WNT2B EML6	2.06e-04	30	113	3	EFO_0010735
Disease	brain disease (implicated_via_orthology)	MYCBP2 TIAM2	2.16e-04	6	113	2	DOID:936 (implicated_via_orthology)
Disease	systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, rheumatoid factor negative, oligoarticular juvenile idiopathic arthritis	RSBN1 FASN PHTF1	4.87e-04	40	113	3	EFO_1001999, EFO_1002019, EFO_1002020
Disease	premature ejaculation	ACOT11 FAM53B	6.41e-04	10	113	2	EFO_0803321
Disease	potassium measurement	WNT2B EML6 AP4E1	6.90e-04	45	113	3	EFO_0009283
Disease	X-11315 measurement	MROH6 KLRG1	7.82e-04	11	113	2	EFO_0021223
Disease	event free survival time, type 1 diabetes mellitus, autoantibody measurement	RSBN1 PHTF1	9.36e-04	12	113	2	EFO_0000482, EFO_0004866, MONDO_0005147
Disease	temporal arteritis	RSBN1 PHTF1	9.36e-04	12	113	2	EFO_1001209
Disease	orotic acid measurement	ABTB2 DNAH11	1.28e-03	14	113	2	EFO_0010516
Disease	non-high density lipoprotein cholesterol measurement	USP34 WDR81 DGKZ BMPR2 PRSS53 CD163L1 B4GALNT3 RAI1 DNAH11	1.71e-03	713	113	9	EFO_0005689
Disease	thyroxine measurement, triiodothyronine measurement	GALNT15 TIAM2	1.90e-03	17	113	2	EFO_0005130, EFO_0008392
Disease	rheumatoid arthritis, ulcerative colitis	RSBN1 PHTF1	2.91e-03	21	113	2	EFO_0000685, EFO_0000729
Disease	Immunosuppressant use measurement	RSBN1 PHTF1	2.91e-03	21	113	2	EFO_0009934
Disease	Attention Deficit Disorder	GRM1 GRM5	3.19e-03	22	113	2	C0041671
Disease	Minimal Brain Dysfunction	GRM1 GRM5	3.19e-03	22	113	2	C1321905
Disease	Epilepsy, Benign Psychomotor, Childhood	GRM1 GRM5	3.49e-03	23	113	2	C0393672
Disease	Epilepsy, Lateral Temporal	GRM1 GRM5	3.49e-03	23	113	2	C0393682
Disease	Uncinate Epilepsy	GRM1 GRM5	3.49e-03	23	113	2	C0014558
Disease	Epilepsy, Temporal Lobe	GRM1 GRM5	3.49e-03	23	113	2	C0014556
Disease	Attention deficit hyperactivity disorder	GRM1 GRM5	3.80e-03	24	113	2	C1263846

Protein segments in the cluster

Peptide	Gene	Start	Entry
STACQRRDWSAHSIV	TDRD1	191	Q9BXT4
SHVAVDVWSTLADFC	SMG6	1051	Q86US8
WASTRRDLFSEAFCA	ADCK2	151	Q7Z695
SCWAHASTSAMADRI	CTSZ	91	Q9UBR2
RANLHVFEDWCGSSI	B4GALNT3	121	Q6L9W6
SRRCSLSLHGVAFWE	ADGRB3	546	O60242
SLLNSRWVLTAAHCF	ACR	76	P10323
ASRTFSSLHVERWAF	ALG5	246	Q9Y673
RTWSHLESIFVCSED	DNAH11	1541	Q96DT5
HERRASDWAVDSNLC	ABCA3	861	Q99758
KWIDTTACLSAERHA	ACOT11	71	Q8WXI4
RLHSSDWNLCTVFGI	C1orf74	161	Q96LT6
SHALKVIAATWCLSF	CCKAR	156	P32238
KHADTWRSVCDSDFS	CD163L1	811	Q9NR16
WRSVCDSDFSLHAAN	CD163L1	816	Q9NR16
ICFSHDCRWVVVSTL	BCAS3	411	Q9H6U6
GLCTVHREADFFWSL	CFLAR	391	O15519
TARSLAHASVWGCLA	CREG2	126	Q8IUH2
VHADVLALWFRSSCS	AP4E1	1106	Q9UPM8
HSACLDSVAKSAWPR	RAI1	646	Q7Z5J4
RWLEDSRHCCSTADF	RAI1	836	Q7Z5J4
INCSVFRDHRATWSV	CAPN15	521	O75808
WVISSLAFCDSSINH	OR8I2	161	Q8N0Y5
TTFKWDSCAAHAILR	INPP1	311	P49441
LSSCWVLTAAHCFKR	PRSS12	666	P56730
ACSRHGSRVLDAIWS	NOP9	556	Q86U38
RDSCWHSAVALEQSI	GRM5	96	P41594
DSWCLVTQLSHERAS	KLHL6	536	Q8WZ60
SLVSWRAFHGCDSAE	MATK	6	P42679
SALCHSWLSLRLFDE	MB21D2	141	Q8IYB1
VFASCSADASIRIWD	GRWD1	276	Q9BQ67
WHLLKIACTQSSARS	CHUK	651	O15111
FADAHTQLACVWART	LRRN2	601	O75325
RLRFNHFATECSWDH	ATRN	171	O75882
EWAAANHVLATCRTA	HERC1	3821	Q15751
TSRWVITAAHCFKDN	PRSS22	81	Q9GZN4
LTRTHWEKFVSVTCD	FETUB	241	Q9UGM5
ILCFHDEAWSTLLRT	GALNT15	196	Q8N3T1
SSLWHREAVTACAVT	FAM53B	76	Q14153
CSSWTHREILQALAA	HEATR6	131	Q6AI08
THALAEWASRREAFA	CDC25B	211	P30305
RICTWFQAELTSVHS	MRC2	851	Q9UBG0
SAHFTGRWDDRSCTE	MRC2	1086	Q9UBG0
AAESSEWTLARCDHA	MROH6	546	A6NGR9
HSLTISFSRCWEFLL	POLE	1901	Q07864
AERWKAFSTCAAHLT	OR6Q1	236	Q8NGQ2
RALVFSVRCWARAHS	MTPAP	351	Q9NVV4
RFSWHQDAVTVTCSD	CRLF2	126	Q9HC73
FAECTTSEWHVTAQR	PKD1L2	321	Q7Z442
DLRWHVASRSECSAQ	ADAMTS9	936	Q9P2N4
WNSSLEFCLARDSHL	KLRG1	96	Q96E93
VASCHSALLCWAARR	C5AR2	216	Q9P296
AAAATCSAVWHDTKI	FBXL8	36	Q96CD0
LSLHTSDWVSSCRLA	BMPR2	291	Q13873
SDWVSSCRLAHSVTR	BMPR2	296	Q13873
VKSAVRCSHVWDITS	CCDC183	306	Q5T5S1
RCSHVWDITSRFLAQ	CCDC183	311	Q5T5S1
LRLRFNHFATECSWD	ATRNL1	131	Q5VV63
SWILVSFACHLASTQ	COL27A1	26	Q8IZC6
CCHLFAWTSAASSVK	MAMLD1	641	Q13495
SWRCVTAERCASLHS	INSRR	271	P14616
LCCWRHSKASASFSE	KIRREL2	531	Q6UWL6
ECSKSLSFITHIDWS	EML6	446	Q6ZMW3
TFHSKEIVAISCSWC	DGKZ	196	Q13574
AHRSIAECAVFTWTN	DIP2A	1481	Q14689
RDSCWHSSVALEQSI	GRM1	106	Q13255
LSSIRWVCSSLRHAQ	FASN	1541	P49327
TAWPADRTADHCAFR	B3GNT8	356	Q7Z7M8
RLSDFLLWQTSHSCL	DHDDS	211	Q86SQ9
HCKNTFLWTEFTDRT	PIP4P1	176	Q86T03
SLIHSAWQRSDSLCR	PLEKHM2	996	Q8IWE5
AKICSRDHAQSSATW	NXPH3	196	O95157
SSVCRRWNEVFHISD	FBXL21P	66	Q9UKT6
SFRACRNLTILWLHS	RTN4R	76	Q9BZR6
FKTVSAVCSLAWHIR	RSBN1	686	Q5VWQ0
AAHSSSSAEWIACLD	RAPGEF4	6	Q8WZA2
LVICSFASTDSIHAW	SLC35D3	201	Q5M8T2
HSTLAAGWICFDRVL	RPGRIP1	711	Q96KN7
SVAACVWGFRHDRSL	TMEM185A	126	Q8NFB2
SVAACVWGFRHDRSL	TMEM185B	126	Q9H7F4
GHATDWRFAVCSFRD	PLEKHG4	16	Q58EX7
SALHWLLRCTAASAE	MED24	126	O75448
RVFRTTWLSTECDSH	KNSTRN	11	Q9Y448
ARWVVSAAHCFSHRD	PRSS57	66	Q6UWY2
VVLSDAFLSRAWCSH	SIGIRR	226	Q6IA17
RFCVRHSWGTDLQSL	SPATA31E1	841	Q6ZUB1
SVAECARAVFASFLW	MYCBP2	3026	O75592
EFHLRITVWSLCTKS	WRAP73	111	Q9P2S5
AVRLVHSWALAESCA	ABTB2	161	Q8N961
HSWALAESCALAAVK	ABTB2	166	Q8N961
EESFWICVASASAHA	CLRN2	186	A0PK11
WTTCLASHLLQAAFE	TMEM270	206	Q6UE05
HESVFTVSLWDCDRK	PIK3CG	346	P48736
LINATWLVSAAHCFT	TMPRSS11E	221	Q9UL52
WVLTAAHCFEKAAAT	PRSS53	71	Q2L4Q9
TEALVHCRTRSWVSF	TAS1R3	716	Q7RTX0
HCRTRSWVSFGLAHA	TAS1R3	721	Q7RTX0
ECGRNFSWRSILTEH	ZNF678	101	Q5SXM1
HSALCSRFAQDLWLE	ZNF138	11	P52744
WVTAVHSACASLFAK	TIAM2	611	Q8IVF5
RWCHIVRDSDSLAES	PHTF1	326	Q9UMS5
LDSSHWAEICETFTR	RMND5B	256	Q96G75
SSVTHLLCASKDFSW	SLC38A2	396	Q96QD8
TRSLLWTREHSSCAE	PLEKHG4B	221	Q96PX9
RHSCAVWAQVKDSSL	SUSD1	706	Q6UWL2
WACGTHSDVLASRLF	TBC1D9	881	Q6ZT07
CTSEFTLTWRRHHCR	FGD6	1231	Q6ZV73
VLVAERWLLSAAHCF	TMPRSS9	856	Q7Z410
SFHLSLAWCVGDARL	USB1	206	Q9BQ65
ECGKAFIWSSTLTRH	ZNF91	466	Q05481
HLFASASCDCTVRLW	WDR38	76	Q5JTN6
DQLFHLSSRSRADCW	TNK1	631	Q13470
ECGKAFIWFSTLTRH	ZNF493	86	Q6ZR52
CGKAFTWSTNLLEHR	ZNF74	281	Q16587
KVCDTAFTWHSQLAR	ZNF611	401	Q8N823
AAAAAHRCSWSSLCR	SLC30A9	6	Q6PML9
WAHCCSLVKSSLADS	USP34	1636	Q70CQ2
WCSLSASKIFIAALH	YIPF7	241	Q8N8F6
VSQFHLLSRDCDSEW	LCMT2	386	O60294
RCKDTATAHSWFVAI	SNTB2	281	Q13425
AWCSSSQEFVAAHRA	WDR81	516	Q562E7
ECGKAFIWSSTLTRH	ZNF254	326	O75437
ECGKAFIWSSTLTRH	ZNF254	466	O75437
WNCTTLDRDHTVFGR	WNT2B	116	Q93097
LASHGLECSSFREAW	ZNF527	116	Q8NB42