Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphorbol ester receptor activity

UNC13B UNC13C

1.04e-052652GO:0001565
GeneOntologyMolecularFunctionnon-kinase phorbol ester receptor activity

UNC13B UNC13C

1.04e-052652GO:0001566
GeneOntologyMolecularFunctionphospholipid binding

UNC13B PITPNM2 BIN1 MARK1 BCAS3 OSBPL1A OSBPL8 UNC13C FCHO2

6.73e-05548659GO:0005543
GeneOntologyCellularComponentcalyx of Held

UNC13B GIT1 UNC13C

1.82e-0436643GO:0044305
GeneOntologyCellularComponentneuromuscular junction

UNC13B DLGAP4 UNC13C PLS3

3.87e-04112644GO:0031594
DomainUnc-13

UNC13B UNC13C

3.57e-053652IPR027080
DomainSUZ

R3HDM2 R3HDM1

7.12e-054652IPR024771
DomainSUZ

R3HDM2 R3HDM1

7.12e-054652PS51673
DomainMunc13_dom-2

UNC13B UNC13C

1.18e-045652IPR014772
DomainMembr_traf_MHD

UNC13B UNC13C

1.18e-045652PF10540
DomainMHD2

UNC13B UNC13C

1.18e-045652PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13C

1.18e-045652IPR019558
DomainDUF1041

UNC13B UNC13C

1.18e-045652SM01145
DomainDUF1041

UNC13B UNC13C

2.48e-047652PF06292
DomainMunc13_1

UNC13B UNC13C

2.48e-047652IPR014770
DomainCAPS_dom

UNC13B UNC13C

2.48e-047652IPR010439
DomainMHD1

UNC13B UNC13C

2.48e-047652PS51258
DomainCalx_beta

FREM2 FREM3

3.29e-048652SM00237
DomainCalx_beta

FREM2 FREM3

4.23e-049652IPR003644
DomainCalx-beta

FREM2 FREM3

4.23e-049652PF03160
DomainR3H

R3HDM2 R3HDM1

4.23e-049652SM00393
DomainR3H

R3HDM2 R3HDM1

6.43e-0411652PS51061
DomainR3H

R3HDM2 R3HDM1

6.43e-0411652PF01424
Domain-

R3HDM2 R3HDM1

6.43e-04116523.30.1370.50
DomainR3H_dom

R3HDM2 R3HDM1

6.43e-0411652IPR001374
DomainCadherin

FREM2 PCDHGA7 FREM3 CDH18

7.62e-04118654IPR002126
DomainOxysterol-bd

OSBPL1A OSBPL8

7.70e-0412652IPR000648
DomainOxysterol-bd_CS

OSBPL1A OSBPL8

7.70e-0412652IPR018494
DomainOxysterol_BP

OSBPL1A OSBPL8

7.70e-0412652PF01237
DomainOSBP

OSBPL1A OSBPL8

7.70e-0412652PS01013
DomainQuino_amine_DH_bsu

NID2 BRWD3

2.63e-0322652IPR011044
DomainSNF2_N

ERCC6L2 CHD1

5.53e-0332652IPR000330
DomainSNF2_N

ERCC6L2 CHD1

5.53e-0332652PF00176
Domain-

SMG7 TTC14 TTC13 TRAPPC8

5.86e-032076541.25.40.10
DomainDNA/RNA_helicase_DEAH_CS

ERCC6L2 CHD1

6.59e-0335652IPR002464
Pubmed

Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.

NID2 FREM2 FREM3

3.43e-061665315878328
Pubmed

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

UNC13B UNC13C

3.44e-06265222674279
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B BIN1 SORBS2 GIT1 OSBPL1A APBA2 OSBPL8 ZMYM2 REV3L R3HDM1 SLX4 BRWD3

4.05e-061285651235914814
Pubmed

Change in INSR, APBA2 and IDE Gene Expressions in Brains of Alzheimer's Disease Patients.

INSR APBA2

1.03e-05365228164769
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13C

1.03e-05365223658173
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13C

1.03e-05365233105896
Pubmed

Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro.

INSR GAB1

1.03e-05365210978177
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13C

1.03e-05365222966208
Pubmed

ZEB1 suppression sensitizes KRAS mutant cancers to MEK inhibition by an IL17RD-dependent mechanism.

ZEB1 IL17RD

1.03e-05365230867319
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13C

1.03e-05365215988013
Pubmed

Expression of Fraser syndrome genes in normal and polycystic murine kidneys.

FREM2 FREM3

1.03e-05365221993971
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HMBOX1 PITPNM2 TSC22D1 SMG7 TECPR2 BCAS3 KAT6A INSR TTC14 PATJ BRWD3 WNK2

1.78e-051489651228611215
Pubmed

Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.

FREM2 FREM3

2.06e-05465224101214
Pubmed

Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.

FREM2 FREM3

2.06e-05465218563433
Pubmed

Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules.

INSR GAB1

2.06e-0546529658397
Pubmed

An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.

UNC13B UNC13C

3.43e-05565234706221
Pubmed

Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.

FREM2 FREM3

3.43e-05565217251066
Pubmed

Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling.

LAT2 GAB1

3.43e-05565212486104
Pubmed

Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer's disease.

BIN1 CDH18

3.43e-05565231878951
Pubmed

nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP).

SORBS2 DLGAP4

3.43e-05565210521485
Pubmed

Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.

FREM2 FREM3

3.43e-05565217596926
Pubmed

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.

UNC13B UNC13C

3.43e-05565226575293
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

PITPNM2 BIN1 SORBS2 GIT1 MARK1 BCAS3 DLGAP4 APBA2 OSBPL8 WNK2

4.76e-051139651036417873
Pubmed

Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.

FREM2 FREM3

5.13e-05665217462874
Pubmed

Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells.

TSC22D1 ZEB1

7.18e-05765220713358
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

UNC13B UNC13C

7.18e-05765236398873
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

ORC2 TSC22D1 ZEB1 OSBPL8 ZMYM2 CHD1 ATL2 SLX4 TOP2B DNTTIP2

7.50e-051203651029180619
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL1A OSBPL8

9.56e-05865217428193
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13B UNC13C

9.56e-05865225609709
Pubmed

Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways.

BIN1 PLS3

9.56e-05865216115810
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

SORBS2 GIT1 MARK1 R3HDM2

1.12e-0413265416944949
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B SORBS2 DLGAP4 R3HDM2 R3HDM1 SON

1.14e-0440765612693553
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

MARK1 DLGAP4 INSR OSBPL8 FCHO2 GAB1

1.37e-0442165636976175
Pubmed

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.

FREM2 FREM3

1.53e-041065215345741
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

BIN1 SORBS2 GIT1 MARK1 DLGAP4 FCHO2

1.54e-0443065632581705
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

ORC2 TOP2B DNTTIP2 SON

1.74e-0414865432538781
Pubmed

The OSBP-related protein family in humans.

OSBPL1A OSBPL8

1.87e-041165211483621
Pubmed

Molecular and functional architecture of striatal dopamine release sites.

UNC13B UNC13C

1.87e-041165234767769
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL1A OSBPL8

2.24e-041265211735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL1A OSBPL8

2.24e-041265212215260
Pubmed

Testis determination requires insulin receptor family function in mice.

INSR FIGLA

2.65e-041365214628051
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MARK1 NRK INSR TTC14 OSBPL8 CHD1 NKAPL DNTTIP2

2.88e-0491065836736316
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PITPNM2 BIN1 SORBS2 GIT1 MARK1 BCAS3 DLGAP4 OSBPL8 PLS3 WNK2

3.07e-041431651037142655
Pubmed

Identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells.

SSMEM1 VWA3B

3.08e-041465215613475
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TSC22D1 MARK1 TTC14 OSBPL8 TRAPPC8 SLX4

3.20e-0449365615368895
Pubmed

Nucleosome-interacting proteins regulated by DNA and histone methylation.

ORC2 CHD1

3.56e-041565221029866
Pubmed

Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication.

ORC2 TOP2B

3.56e-041565212393188
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

BIN1 OSBPL8 CHD1 TTC13 R3HDM1 PATJ ATL2

4.33e-0473365734672954
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

LAT2 CHD1 TOP2B DNTTIP2 SON

4.43e-0434065529478914
Pubmed

Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays.

BIN1 DLGAP4

4.59e-041765216275660
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FREM2 FREM3

5.16e-041865214730302
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

UNC13B GIT1 ZMYM2 TOP2B SON

5.60e-0435865532460013
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

ORC2 NID2 ZMYM2 TOP2B

5.78e-0420365422083510
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BIN1 SORBS2 ZEB1 GIT1 ZMYM2 TOP2B SON

5.98e-0477465715302935
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

SORBS2 TTC14

6.39e-042065221689717
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

ZMYM2 CHD1 REV3L SLX4

8.06e-0422265437071664
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

SMG7 GIT1 ZMYM2 PATJ SLX4 GAB1

8.08e-0458865638580884
Pubmed

PEA15 regulates the DNA damage-induced cell cycle checkpoint and oncogene-directed transformation.

OSBPL1A SON

9.24e-042465224710276
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DLGAP4 R3HDM2 TRAPPC8

9.37e-0410265310231032
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

LAT2 KAT6A R3HDM2 R3HDM1 BEND2 WNK2

9.60e-0460865616713569
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ORC2 KAT6A ZMYM2 CHD1 TOP2B DNTTIP2

9.60e-0460865636089195
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PITPNM2 MARK1 OSBPL8

9.64e-0410365310819331
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

ZMYM2 TRAPPC8 TOP2B

9.64e-0410365332744500
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B PITPNM2 LAT2 BCAS3 KAT6A REV3L IL17RD WNK2

1.03e-03110565835748872
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

ZMYM2 SLX4 TOP2B

1.05e-0310665319394292
Pubmed

Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.

UNC13B UNC13C

1.09e-032665217124501
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 SMG7 KAT6A APBA2 REV3L BRWD3 DNTTIP2 SON

1.10e-03111665831753913
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SORBS2 GIT1 BCAS3 OSBPL8 R3HDM1 PATJ GAB1

1.11e-0386165736931259
Pubmed

BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.

MARK1 ATL2 SLX4 WNK2 DNTTIP2

1.13e-0341965533001583
Pubmed

Proteomic analysis of FOXP proteins reveals interactions between cortical transcription factors associated with neurodevelopmental disorders.

BNC2 ZMYM2

1.26e-032865229365100
Pubmed

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.

SKIDA1 PLS3

1.26e-032865233953184
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

NID2 FREM2

1.35e-032965222613833
Pubmed

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.

CHD1 GAB1

1.45e-033065212522270
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SORBS2 MARK1 R3HDM2 R3HDM1 PATJ

1.49e-0344665524255178
Pubmed

The synaptic vesicle cycle.

UNC13B UNC13C

1.54e-033165215217342
Pubmed

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

TSC22D1 TRAPPC8 PLS3 TOP2B

1.68e-0327165425737280
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ORC2 SMG7 ZMYM2 CHD1 TOP2B DNTTIP2 SON

1.77e-0393465733916271
Pubmed

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.

ZMYM2 TTC13 R3HDM1 IL17RD PLS3 GAB1

1.77e-0368665629987050
Pubmed

SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.

APBA2 SLX4

1.86e-033465231495888
GeneFamilyUNC13 homologs

UNC13B UNC13C

2.86e-054402836
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL1A OSBPL8

3.11e-0412402670
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

ORC2 KAT6A OSBPL8 ZMYM2 RNF13 R3HDM2 CHD1 REV3L TRAPPC8 R3HDM1

2.14e-074666510M13522
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

ORC2 ZEB1 KAT6A OSBPL8 ZMYM2 RNF13 R3HDM2 CHD1 REV3L TRAPPC8 R3HDM1 SON

1.12e-068566512M4500
CoexpressionGSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_UP

NRK KAT6A OSBPL8 REV3L PATJ LAX1

3.57e-06166656M9015
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

OSBPL1A OSBPL8 RNF13 CHD1 REV3L TRAPPC8 PLS3 TOP2B SON

3.34e-05656659M18979
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN

VWA3B FCHO2 R3HDM1 BRWD3 SON

5.83e-05166655M6826
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

BIN1 ZEB1 KAT6A TTC14 APBA2 OSBPL8 CHD1 REV3L TRAPPC8 TOP2B LAX1 DNTTIP2 SON

6.39e-0514926513M40023
CoexpressionGSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN

PITPNM2 IKZF2 ZEB1 PATJ TOP2B

6.71e-05171655M6321
CoexpressionGSE14699_NAIVE_VS_ACT_CD8_TCELL_DN

ZEB1 INSR ZMYM2 PATJ SON

7.48e-05175655M2940
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000

BNC2 PDE3A MARK1 NRK INSR TTC14 ERCC6L2 REV3L ATL2 TOP2B

6.02e-083306510DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000

BNC2 PDE3A MARK1 NRK INSR ERCC6L2 CHD1 REV3L ATL2 TOP2B

1.70e-073696510DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#5_top-relative-expression-ranked_500

PDE3A NRK INSR ERCC6L2 REV3L ATL2 TOP2B

2.12e-06194657DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k5_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

BCAS3 NRK INSR TTC14 ERCC6L2 CHD1 REV3L ATL2 SON

2.52e-06385659gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000

BNC2 FREM2 IKZF2 NRK OSBPL1A TTC14 ERCC6L2 OSBPL8 CHD1 BRWD3 TOP2B SON

7.56e-068366512gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_M-vs-F_top274_274

BNC2 FREM2 IKZF2 NRK ERCC6L2 OSBPL8 TOP2B

1.31e-05256657gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_250_M-vs-F
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000

BNC2 PDE3A NRK INSR TTC14 ERCC6L2 ATL2 TOP2B

2.77e-05397658gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000

BNC2 PDE3A IKZF2 MARK1 NRK INSR ERCC6L2 CHD1 REV3L ATL2 TOP2B

3.03e-058066511DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

BNC2 PDE3A GPR37 NRK INSR TTC14 ERCC6L2 ATL2 BRWD3 TOP2B SON

3.20e-058116511gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

IKZF2 MARK1 BCAS3 NRK INSR TTC14 ERCC6L2 CHD1 REV3L ATL2 SON

3.47e-058186511gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_k-means-cluster#3_top-relative-expression-ranked_1000

PDE3A ERCC6L2 REV3L ATL2

4.16e-0563654gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#2_top-relative-expression-ranked_1000

PDE3A MARK1 NRK INSR ERCC6L2 REV3L ATL2

4.64e-05312657gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k2
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_500

PDE3A SORBS2 MARK1 PLS3

8.69e-0576654gudmap_kidney_P0_JuxtaGlom_Ren1_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_500

ERCC6L2 REV3L ATL2 TOP2B

9.62e-0578654gudmap_developingKidney_e15.5_Cap mesenchyme_500_k5
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000

SORBS2 IKZF2 INSR TTC14 ERCC6L2 CHD1 REV3L PATJ ATL2 TOP2B

1.14e-047746510gudmap_developingKidney_e15.5_cortic collect duct_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_200

BNC2 FREM2 NRK

1.40e-0433653gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k3_200
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

INSR TTC14 ERCC6L2 CHD1 REV3L ATL2 TOP2B

1.46e-04375657gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

BNC2 PDE3A MARK1 NRK INSR TTC14 ERCC6L2 REV3L ATL2 TOP2B

1.79e-048186510DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500

SORBS2 IKZF2 INSR ERCC6L2 REV3L PATJ ATL2

1.86e-04390657gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_k-means-cluster#1_top-relative-expression-ranked_1000

IKZF2 ERCC6L2 REV3L ATL2 TOP2B

1.88e-04173655gudmap_developingLowerUrinaryTract_e15.5_Urothelium_1000_k1
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_1000

BNC2 TSC22D1 REV3L PLS3

2.24e-0497654gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_500

PDE3A NRK INSR ERCC6L2 REV3L ATL2 TOP2B

2.45e-04408657DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_500
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

INSR ERCC6L2 CHD1 REV3L ATL2

3.77e-04201655gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500

SORBS2 ERCC6L2 REV3L ATL2

4.57e-04117654gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_200

SORBS2 ERCC6L2 REV3L

5.13e-0451653gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

FREM2 SORBS2 IKZF2 MARK1 INSR ERCC6L2 CHD1 REV3L ATL2

5.32e-04769659gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

PDE3A ERCC6L2 OSBPL8 CHD1 REV3L R3HDM1 ATL2 BRWD3 TOP2B

5.47e-04772659gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#1_top-relative-expression-ranked_200

PDE3A ERCC6L2 REV3L

5.75e-0453653gudmap_developingLowerUrinaryTract_e14.5_ urethra_200_k1
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#3_top-relative-expression-ranked_200

ERCC6L2 REV3L ATL2

6.07e-0454653gudmap_developingKidney_e15.5_cortic collect duct_200_k3
CoexpressionAtlasalpha beta T cells, T.DPsm.Th, 4+ 8+ TCR-/lo FSClo, Thymus, avg-3

PITPNM2 IKZF2 CHD1 PATJ ATL2 TOP2B

6.30e-04343656GSM399400_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#1_top-relative-expression-ranked_500

PDE3A NRK INSR TTC14 ERCC6L2

7.09e-04231655gudmap_developingLowerUrinaryTract_e14.5_ bladder_500_k1
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_1000

SORBS2 IKZF2 TTC14 ERCC6L2 CHD1 REV3L R3HDM1 PATJ ATL2

7.12e-04801659gudmap_developingKidney_e15.5_ureter tip_1000_flank cortic collct
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000

PDE3A IKZF2 MARK1 NRK INSR ERCC6L2 REV3L PATJ ATL2

7.44e-04806659gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000

BNC2 OSBPL1A TTC14 OSBPL8 CHD1 BRWD3 SON

7.50e-04492657gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000_k5
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#4_top-relative-expression-ranked_500

BNC2 GPR37 NRK

8.27e-0460653gudmap_developingGonad_e12.5_ovary_k4_500
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HMBOX1 PITPNM2 ZEB1 GIT1 KAT6A OSBPL1A FCHO2

1.73e-0820065779e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 BNC2 PDE3A ZEB1 NRK PATJ

3.21e-07187656c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSC22D1 NRK UNC13C B4GALNT3 PATJ GAB1

3.21e-07187656f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TSC22D1 NRK UNC13C B4GALNT3 PATJ GAB1

3.41e-07189656e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A SORBS2 INSR B4GALNT3 PATJ WNK2

4.10e-0719565675fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

HMBOX1 PITPNM2 ZEB1 GIT1 KAT6A FCHO2

4.75e-07200656bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

HMBOX1 PITPNM2 ZEB1 GIT1 KAT6A FCHO2

4.75e-07200656432384faeade8e609154fab3d96c955a8ec868dd
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 FREM2 UNC13C FREM3 IL17RD

5.44e-0617365530d67738633493d47f06ae452424382f069b6c0a
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HMBOX1 FREM2 NRK UNC13C LAX1

5.59e-06174655c58328c2f262506a4518f49f148e29874faf9171
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 FREM2 UNC13C FREM3 IL17RD

5.59e-06174655a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

BNC2 TSC22D1 PDE3A ZEB1 GPR37

6.77e-061816557e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDE3A ZEB1 MARK1 REV3L PLS3

6.96e-06182655ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

UNC13B PITPNM2 UNC13C PATJ ATL2

7.53e-06185655673f0c688ae6984bc8027df2da335787924f4137
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 FREM2 UNC13C IL17RD WNK2

7.53e-06185655636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

SORBS2 INSR B4GALNT3 PATJ WNK2

7.93e-06187655ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

UNC13B FREM2 SORBS2 IKZF2 PATJ

7.93e-06187655db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BIN1 LAT2 NKAPL DNTTIP2 SON

7.93e-06187655ba822dbceb47257129d6a8c9639c08d76de6d6a3
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

SORBS2 B4GALNT3 PATJ WNK2 GAB1

7.93e-0618765578cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

BNC2 ZEB1 MARK1 UNC13C PLS3

8.35e-0618965544e37f88137bb249933eb615235b2cf2ae7f3925
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

SORBS2 B4GALNT3 PATJ WNK2 GAB1

8.35e-061896559c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

PDE3A SORBS2 B4GALNT3 PATJ WNK2

8.35e-061896555e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

SORBS2 INSR B4GALNT3 PATJ WNK2

8.57e-06190655756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellLV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

PDE3A SORBS2 B4GALNT3 PATJ WNK2

8.57e-06190655de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

UNC13B FREM2 SORBS2 IKZF2 PATJ

8.57e-06190655625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellMesenchymal_cells-Smooth_muscle|World / Lineage and Cell class

PDE3A SORBS2 MARK1 STYXL2 PLS3

8.57e-061906555aa62a363a25f4a110136263b21289a11e8c1e6d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

PDE3A SORBS2 B4GALNT3 PATJ WNK2

8.57e-06190655fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

PDE3A SORBS2 B4GALNT3 PATJ WNK2

8.79e-0619165525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B FREM2 SORBS2 B4GALNT3 PATJ

8.79e-06191655e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

UNC13B FREM2 SORBS2 B4GALNT3 PATJ

9.01e-06192655499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 SORBS2 BCAS3 INSR PATJ

9.01e-06192655e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSC22D1 TTC14 CHD1 FCHO2 SON

9.48e-06194655e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

PDE3A SORBS2 B4GALNT3 PATJ WNK2

9.72e-06195655f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSC22D1 PDE3A UNC13C R3HDM1 CDH18

9.72e-06195655787e95fb59c40bba784544b662fac37606ae1427
ToppCellmLN-(2)_B_cell-(20)_B_cell_IgA_Plasma|mLN / shred on region, Cell_type, and subtype

NID2 INSR VWA3B GAB1 CDH18

1.02e-05197655a39b384ee9824a08c3b544a9c3c7f0f95f08d6a7
ToppCellmLN-B_cell-B_cell_IgA_Plasma|mLN / Region, Cell class and subclass

NID2 INSR VWA3B GAB1 CDH18

1.02e-0519765520822fce311326765b71337ce501ba44ea14f58f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSC22D1 SORBS2 OSBPL8 R3HDM1 CDH18

1.05e-051986550ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 ZEB1 GIT1 KAT6A FCHO2

1.10e-0520065572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 ZEB1 GIT1 KAT6A FCHO2

1.10e-052006555c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PITPNM2 ZEB1 GIT1 DLGAP4 OSBPL1A

1.10e-052006557034f57e282982c19c13ee8ab78eabaffa069e30
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NID2 TSC22D1 PDE3A MARK1

8.39e-0515865484c0a215dabf697ada036c2b9592d0c61b5077de
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B FREM2 UNC13C WNK2

8.39e-05158654f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UNC13B FREM2 UNC13C WNK2

8.39e-051586548c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9

HMBOX1 OSBPL1A REV3L GAB1

8.60e-05159654fb222c42f66901852b01cec073ec0732245ee973
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SORBS2 INSR B4GALNT3 WNK2

9.02e-051616542d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCelllymphoid-B_cell-pro-B|World / Lineage, cell class and subclass

NID2 LAT2 SKIDA1 GAB1

9.02e-0516165423138e579f07d5a6f20d41457cb573b4ac95a4ef
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ZEB1 APBA2 PATJ FREM3

1.04e-0416765478d264af390bd89942ffbb2991dc94f50756d4c9
ToppCellControl|World / group, cell type (main and fine annotations)

UNC13B FREM2 SORBS2 PATJ

1.06e-04168654a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SORBS2 NRK APBA2 ATL2

1.14e-04171654d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

PDE3A ZEB1 MARK1 BEND2

1.16e-04172654858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 ZEB1 MARK1 UNC13C

1.19e-041736541f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B FREM2 PATJ FREM3

1.19e-04173654b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 MARK1 BCAS3 UNC13C

1.22e-04174654197686570cec6d96a92e77e6409325d3bfe6f991
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GPR37 R3HDM2 SLX4 WNK2

1.22e-041746543f0a5ce074675d57d479fa069385a1b3071e884e
ToppCellfacs-Heart-LV-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORBS2 MARK1 BCAS3 UNC13C

1.22e-041746542eee7b5471672b439f95eba11494c2adf8cb7006
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A SORBS2 MARK1 BCAS3

1.30e-04177654dbdbdc8ed9ef0b529694242ef9f9f07a42e16005
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NID2 PDE3A ZEB1 MARK1

1.33e-04178654185b44700f06ec58b3c09c80520502166c965fd6
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 FREM2 UNC13C LAX1

1.33e-04178654a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCelldroplet-Heart-nan-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A SORBS2 MARK1 BCAS3

1.33e-04178654416f85e51f45ec7949451fd47611a84e33e87245
ToppCell21-Trachea-Epithelial-Submucosal_gland|Trachea / Age, Tissue, Lineage and Cell class

INSR ATL2 IL17RD WNK2

1.33e-041786543e406e38eea0d38dc25edecf703c4c89ec6a28e0
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A SORBS2 MARK1 BCAS3

1.36e-041796548da6863edc756540bb097cc7221c1408640d9bb4
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IKZF2 B4GALNT3 PATJ WNK2

1.36e-041796546e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A SORBS2 MARK1 BCAS3

1.36e-04179654f39c13c99a07d009cc677e363ffe089089c64916
ToppCellLV|World / Chamber and Cluster_Paper

SORBS2 B4GALNT3 PATJ GAB1

1.39e-041806545ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

BNC2 ZEB1 MARK1 UNC13C

1.39e-0418065401f2e5d96016823482f89ba503d007d4bd88eeac
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 PITPNM2 ZEB1 GIT1

1.39e-04180654544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

UNC13B FREM2 PATJ ATL2

1.42e-04181654c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A CHD1 FCHO2 TOP2B

1.45e-04182654f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellsevere_influenza-Platelet|severe_influenza / disease group, cell group and cell class (v2)

PITPNM2 TSC22D1 PDE3A BEND2

1.45e-041826542018b71ec26bf3cd7ecdc04d5473900a697cd58a
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BNC2 FREM2 UNC13C LAX1

1.45e-041826549966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SORBS2 NRK TRAPPC8 WNK2

1.45e-0418265400a148b1e499bf16325491536d187d4dd6b70c06
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgM_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NID2 RBM44 INSR

1.47e-0470653aa63c1b77a9fb15e75835cb3781f2d890f3fe328
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

UNC13B FREM2 SORBS2 PATJ

1.48e-041836546847c1252d6bb105524f812658112517fd351eab
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

SORBS2 INSR B4GALNT3 WNK2

1.48e-04183654940cbe298e9c53b5622af09264586ed823d3141f
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

MARK1 B4GALNT3 PATJ PLS3

1.48e-041836540f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NID2 SORBS2 NRK APBA2

1.48e-041836541464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

UNC13B FREM2 SORBS2 PATJ

1.51e-04184654369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B PATJ PLS3 GAB1

1.51e-0418465457c792e6e2fedba25d3350ffe649fd74750b579d
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A CHD1 FCHO2 TOP2B

1.51e-041846541154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SORBS2 R3HDM1 FREM3 CDH18

1.51e-0418465434e316ad8e7b8667cd8ad61397281802a252744f
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

UNC13B PATJ PLS3 GAB1

1.51e-04184654d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 PDE3A ZEB1 NRK

1.54e-041856547dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

UNC13B B4GALNT3 PATJ WNK2

1.54e-04185654cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellControl-Epithelial-Club|Epithelial / Disease state, Lineage and Cell class

INSR FAXC ATL2 WNK2

1.54e-041856546814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KAT6A CHD1 FCHO2 TOP2B

1.54e-041856547adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

UNC13B FREM2 PATJ ATL2

1.57e-041866542ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

UNC13B OSBPL1A R3HDM2 R3HDM1

1.57e-0418665456c139e679d640ea901ead657a8e8887e0fca098
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

UNC13B FREM2 SORBS2 PATJ

1.57e-04186654bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 ZEB1 NRK PATJ

1.57e-04186654f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 PDE3A LAT2 LAX1

1.60e-04187654bdcef4f3e093c3646b639a189bbe93d6f4c40f3c
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 PDE3A LAT2 LAX1

1.60e-0418765409348f1e8bbbca8dca885461937b9b1dd248b034
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BNC2 PDE3A ZEB1 NRK

1.60e-041876545258674d0346e5c51a4b965efcdc1790c970845d
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 PDE3A LAT2 LAX1

1.60e-041876540f7a42c55997e34a0d20e492e16b03e91e965335
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 PDE3A LAT2 LAX1

1.60e-04187654064730fa72f8637c3db3fc34d2e363d2b9a38f1d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 PDE3A ZEB1 NRK

1.60e-0418765413731298bc562ec29582f5da1b4c97261284f6f1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SORBS2 GPR37 ATL2 WNK2

1.60e-0418765471d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZEB1 MARK1 UNC13C PLS3

1.60e-04187654c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

BNC2 PDE3A ZEB1 MARK1

1.60e-04187654bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 PITPNM2 ZEB1 GIT1

1.64e-0418865473f6ec915934154f435a376cb274b058ff7c5f35
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

UNC13B PITPNM2 BCAS3 PLS3

1.64e-0418865488b3415e33db81726dd29c1f50c886e057af50a0
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

TSC22D1 PDE3A UNC13C PLS3

1.64e-0418865434e1b074a3995aa46ab194eb45115d76d1a5514d
Diseaseblood urea nitrogen measurement

IKZF2 BCAS3 INSR R3HDM2 FCHO2 GAB1

3.72e-04452626EFO_0004741
Diseaseprostate adenocarcinoma (is_implicated_in)

BIN1 INSR

8.05e-0420622DOID:2526 (is_implicated_in)
DiseaseFEV/FEC ratio

NID2 BNC2 FREM2 PDE3A BCAS3 SKIDA1 ERCC6L2 R3HDM2 TOP2B

1.01e-031228629EFO_0004713
DiseaseAdenoid Cystic Carcinoma

KAT6A IL17RD SON

1.24e-03100623C0010606
Diseasecortex volume change measurement, age at assessment

UNC13C WNK2

1.59e-0328622EFO_0008007, EFO_0021500
Diseasehair colour measurement

BNC2 FREM2 DLGAP4 APBA2 UNC13C REV3L

1.83e-03615626EFO_0007822
Diseasepresubiculum volume

REV3L WNK2

1.94e-0331622EFO_0009400

Protein segments in the cluster

PeptideGeneStartEntry
EDHDIDQGVSSNSSY

B4GALNT3

91

Q6L9W6
SLSTQNEYNESSESE

BNC2

356

Q6ZN30
ENHFYSSSDSDSEDE

FCHO2

336

Q0JRZ9
ESTSRTDQDYVDGDH

BRWD3

1626

Q6RI45
LRSQSDLDDQHDYDS

GIT1

371

Q9Y2X7
DSSSDYVNNTSEEED

APBA2

71

Q99767
SYDSLASDHSGQEDE

BCAS3

706

Q9H6U6
KENTNHDDSSRDSYS

CHD1

1531

O14646
STESAQDTYLDSQDH

DLGAP4

581

Q9Y2H0
SSQEYTDSTGIDLHE

R3HDM1

141

Q15032
DSSQEYTDSTGIDLH

R3HDM2

141

Q9Y2K5
QKHDTDEDSQQEYHS

RBM44

176

Q6ZP01
AQDHDSEDNAQITYS

PCDHGA7

476

Q9Y5G6
HDDDNTIYESEESSE

FAXC

336

Q5TGI0
QENIYSHLDEESSES

IL17RD

326

Q8NFM7
TTSSSDSHDSEENYV

GAB1

576

Q13480
SSIIYEHDDSETQED

FREM2

1261

Q5SZK8
DNSTNDIADDSTYVT

BEND2

36

Q8NDZ0
DYSEQDDSTSHSDHQ

HMBOX1

371

Q6NT76
ELSSEGTQHSYSEEE

PLS3

111

P13797
VTSDYETNNNSDSSD

PDE3A

621

Q14432
DCASISSEDSHDYVN

LAX1

181

Q8IWV1
SEDSQKHNQSEYEDS

INSR

691

P06213
SDSSTYELDTIQQHQ

PITPNM2

666

Q9BZ72
STHYCSQDQLTDEEE

OSBPL1A

336

Q9BXW6
DSTDSESSHDDHQSY

IKZF2

406

Q9UKS7
ETTYTEQSHEELGEA

OSBPL8

376

Q9BZF1
SHATALESDYNEDNL

NID2

301

Q14112
LTQEESSEHEGAYQD

KAT6A

1431

Q92794
STVTSDDNDNEYTTE

GPR37

576

O15354
NHVSSTTSLGENYED

ATL2

31

Q8NHH9
NERDTENHTSVDGYT

MARK1

11

Q9P0L2
SSLDSATTQSDQDYH

CDH18

751

Q13634
DPDEQSYSNNSSESH

FIGLA

131

Q6QHK4
NEDHNSQFIDDYSSS

ERCC6L2

1041

Q5T890
QAQHDYTATDTDELQ

BIN1

526

O00499
DESNDTFEDTYDHAN

NRK

936

Q7Z2Y5
EDEESEDYQNSASIH

LAT2

186

Q9GZY6
HSDSESEYSASNSED

ORC2

176

Q13416
QEASTIVYEHDDSET

FREM3

1261

P0C091
EDETQNQHDDSSSDS

TOP2B

1121

Q02880
DSLENTLTESEAHYS

KRT34

336

O76011
NQHDSDTTEYGSEES

SSMEM1

141

Q8WWF3
FSNETEQHTYSQDEQ

SMG7

311

Q92540
SDSESSSYSDHAAND

SKIDA1

381

Q1XH10
SHQNMTESSDYEEDD

RNF13

331

O43567
SSNNSIAEDTESYDD

TSC22D1

126

Q15714
SDSDQDGVVSDHSDY

SORBS2

596

O94875
YTHQTLDSDSEDESQ

SLX4

1601

Q8IY92
YSDSDSNSESDTNSD

NKAPL

201

Q5M9Q1
ETSEAESNYSVSEHH

DNTTIP2

86

Q5QJE6
ISEDYATAHEDFQQS

TTC13

261

Q8NBP0
CHSDLQDDSESYDLT

UNC13C

701

Q8NB66
QDDSESYDLTQDDNS

UNC13C

706

Q8NB66
NYETEDSESSFVTHN

REV3L

926

O60673
DNEEESCYILHSSSN

PATJ

776

Q8NI35
SKSQSEEQDTSSYHE

STYXL2

981

Q5VZP5
ATSEINEDSEDHYAI

TTC14

86

Q96N46
SSQLSELDQYHEQDD

UNC13B

271

O14795
DQTLTSSDEEDIYAH

TECPR2

746

O15040
TNYNTVVETNSDSDD

ZEB1

21

P37275
VSGYQSHDDSSDNSE

ZMYM2

1051

Q9UBW7
QAATHVSLDQEYDSE

TRAPPC8

691

Q9Y2L5
EGSQVYDHDSSDVSS

VWA3B

831

Q502W6
HSQSSYISSDNDSEL

WNK2

1911

Q9Y3S1
YDVDLSLTTQDTEHD

SON

1626

P18583