Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	palmitoyl-(protein) hydrolase activity	ABHD17A ABHD17C ABHD17B	5.65e-05	13	119	3	GO:0008474
GeneOntologyMolecularFunction	palmitoyl hydrolase activity	ABHD17A ABHD17C ABHD17B	7.16e-05	14	119	3	GO:0098599
GeneOntologyMolecularFunction	thiolester hydrolase activity	ABHD17A BAAT ABHD17C ABHD17B	1.75e-04	47	119	4	GO:0016790
GeneOntologyBiologicalProcess	negative regulation of protein localization to microtubule	ABHD17A ABHD17C ABHD17B	1.95e-06	5	121	3	GO:1902817
GeneOntologyBiologicalProcess	regulation of protein localization to microtubule	ABHD17A ABHD17C ABHD17B	1.95e-06	5	121	3	GO:1902816
GeneOntologyBiologicalProcess	protein depalmitoylation	ABHD17A ABHD17C ABHD17B	2.29e-05	10	121	3	GO:0002084
GeneOntologyBiologicalProcess	protein localization to microtubule cytoskeleton	ABHD17A CEP192 ABHD17C ABHD17B HTT	2.48e-05	59	121	5	GO:0072698
GeneOntologyBiologicalProcess	protein localization to cytoskeleton	ABHD17A CEP192 ABHD17C ABHD17B HTT	3.42e-05	63	121	5	GO:0044380
GeneOntologyBiologicalProcess	macromolecule depalmitoylation	ABHD17A ABHD17C ABHD17B	6.84e-05	14	121	3	GO:0098734
GeneOntologyBiologicalProcess	positive regulation of protein localization to endosome	ABHD17A ABHD17C ABHD17B	6.84e-05	14	121	3	GO:1905668
GeneOntologyBiologicalProcess	regulation of protein localization to endosome	ABHD17A ABHD17C ABHD17B	8.51e-05	15	121	3	GO:1905666
GeneOntologyBiologicalProcess	lipoprotein catabolic process	ABHD17A ABHD17C ABHD17B	1.26e-04	17	121	3	GO:0042159
GeneOntologyBiologicalProcess	spongiotrophoblast layer development	BIRC6 NRK HECTD1	1.51e-04	18	121	3	GO:0060712
GeneOntologyBiologicalProcess	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	STAT1 CTNNB1	2.03e-04	4	121	2	GO:0003340
GeneOntologyBiologicalProcess	protein localization to microtubule	ABHD17A ABHD17C ABHD17B	2.09e-04	20	121	3	GO:0035372
GeneOntologyCellularComponent	microtubule organizing center	PDE4D OBSL1 FRMD8 CEP192 DCLRE1B ECPAS BIRC6 CEP164 TTLL12 PJA2 MAPK15 RUVBL1 WDR90 HOOK2 NUP93 CTNNB1 HTT	2.47e-05	919	122	17	GO:0005815
GeneOntologyCellularComponent	centrosome	PDE4D OBSL1 FRMD8 CEP192 DCLRE1B ECPAS BIRC6 CEP164 TTLL12 PJA2 RUVBL1 WDR90 HOOK2 NUP93 CTNNB1	4.30e-05	770	122	15	GO:0005813
Domain	YIPPEE	YPEL3 YPEL2 YPEL1	2.63e-06	5	121	3	PS51792
Domain	Yippee/Mis18/Cereblon	YPEL3 YPEL2 YPEL1	1.45e-05	8	121	3	IPR004910
Domain	Yippee-Mis18	YPEL3 YPEL2 YPEL1	1.45e-05	8	121	3	PF03226
Domain	Hydrolase_4	ABHD17A ABHD17C ABHD17B	2.17e-05	9	121	3	IPR022742
Domain	Hydrolase_4	ABHD17A ABHD17C ABHD17B	2.17e-05	9	121	3	PF12146
Domain	Transcrp_activ_Zfx/Zfy-dom	ZFX ZNF711	1.24e-04	3	121	2	IPR006794
Domain	Zfx_Zfy_act	ZFX ZNF711	1.24e-04	3	121	2	PF04704
Domain	-	ABHD17A BAAT FAM135B ABHD17C ABHD17B SERAC1	1.25e-04	119	121	6	3.40.50.1820
Domain	AB_hydrolase	ABHD17A BAAT FAM135B ABHD17C ABHD17B SERAC1	1.25e-04	119	121	6	IPR029058
Domain	ARM-type_fold	SARM1 LRRK2 ECPAS RYR3 THADA SERAC1 CTNNB1 HECTD1 HTT	3.66e-04	339	121	9	IPR016024
Domain	-	SARM1 LRRK2 ECPAS SERAC1 CTNNB1 HECTD1 HTT	6.12e-04	222	121	7	1.25.10.10
Pubmed	ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization.	ABHD17A ABHD17C ABHD17B	1.72e-07	4	123	3	26701913
Pubmed	Dynamic Palmitoylation Targets MAP6 to the Axon to Promote Microtubule Stabilization during Neuronal Polarization.	ABHD17A ABHD17C ABHD17B	4.29e-07	5	123	3	28521134
Pubmed	Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.	YPEL3 YPEL2 YPEL1	4.29e-07	5	123	3	15556292
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ESPN PDE4D HDAC8 HECTD4 SRPK2 CEP192 ECPAS LRRC8D HPS3 TASOR2 THADA SLC16A14 MACROH2A2 ASPSCR1 HOOK2 SPIDR HECTD1 CRAMP1 HTT	1.25e-06	1489	123	19	28611215
Pubmed	Identification of PSD-95 Depalmitoylating Enzymes.	ABHD17A ABHD17C ABHD17B	1.50e-06	7	123	3	27307232
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MGAT4B INPPL1 HECTD4 FRMD8 EXOSC8 CEP192 ITGA3 BIRC6 EIF6 THADA ADAMTS7 KCNK5 WDR90 HECTD1 CRAMP1 HTT	1.90e-06	1105	123	16	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CASP8AP2 ISLR2 KIF16B HECTD4 ECPAS ZFYVE1 DICER1 WDR90 NUP93 CRAMP1 MINDY1	3.02e-06	529	123	11	14621295
Pubmed	Praja1, a novel gene encoding a RING-H2 motif in mouse development.	ZFX PJA2 PJA1	3.57e-06	9	123	3	9393880
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	AHCTF1 ZNF318 ECPAS BIRC6 EIF6 DICER1 TASOR2 TTLL12 IGF2BP3 NUP93 HECTD1 ANKRD52	3.75e-06	653	123	12	22586326
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	DENND4A CEP192 ECPAS BIRC6 CYFIP2 STRIP1 CTNNB1 HECTD1 ANKRD52 THAP12	4.49e-06	446	123	10	24255178
Pubmed	YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.	YPEL3 YPEL2 YPEL1	5.09e-06	10	123	3	20580816
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ISLR2 ARRDC4 FAT3 AHCTF1 OBSL1 SRPK2 ZNF318 ITGA3 DICER1 ENY2 ZNF711 PJA2 THADA MACROH2A2 ANKRD52	9.91e-06	1116	123	15	31753913
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	AHCTF1 SARM1 ECPAS STAT1 STRIP1 IGF2BP3 RUVBL1 VCAN MACROH2A2 CTNNB1	1.17e-05	498	123	10	36634849
Pubmed	Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene.	NODAL DNAH11	1.24e-05	2	123	2	23316472
Pubmed	Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever.	STAT1 IFNAR1	1.24e-05	2	123	2	34077751
Pubmed	Versican gene: regulation by the β-catenin signaling pathway plays a significant role in dermal papilla cell aggregative growth.	VCAN CTNNB1	1.24e-05	2	123	2	23099107
Pubmed	Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways.	STAT1 IFNAR1	1.24e-05	2	123	2	11932417
Pubmed	Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus.	STAT1 IFNAR1	1.24e-05	2	123	2	23903830
Pubmed	Clinicopathologic Characteristics of Thyroid Nodules Positive for the THADA-IGF2BP3 Fusion on Preoperative Molecular Analysis.	IGF2BP3 THADA	1.24e-05	2	123	2	33487086
Pubmed	Requirement for STAT1 in LPS-induced gene expression in macrophages.	STAT1 IFNAR1	1.24e-05	2	123	2	11310846
Pubmed	STAT1 signaling in CD8 T cells is required for their clonal expansion and memory formation following viral infection in vivo.	STAT1 IFNAR1	1.24e-05	2	123	2	18250422
Pubmed	Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites.	STAT1 IFNAR1	1.24e-05	2	123	2	20483775
Pubmed	A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.	STAT1 IFNAR1	1.24e-05	2	123	2	15851485
Pubmed	Dicer is required for proper liver zonation.	DICER1 CTNNB1	1.24e-05	2	123	2	19718708
Pubmed	Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38.	STAT1 IFNAR1	1.24e-05	2	123	2	39002130
Pubmed	Interferon alpha receptors and STAT1 as therapy predictors of a sustained virological response in hepatitis C/B co-infection.	STAT1 IFNAR1	1.24e-05	2	123	2	30410131
Pubmed	Beta catenin is regulated by its subcellular distribution and mutant huntingtin status in Huntington's disease cell STHdhQ111/HdhQ111.	CTNNB1 HTT	1.24e-05	2	123	2	29894684
Pubmed	Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling.	STAT1 IFNAR1	1.24e-05	2	123	2	20978541
Pubmed	β-catenin downregulates Dicer to promote ovarian cancer metastasis.	DICER1 CTNNB1	1.24e-05	2	123	2	28650464
Pubmed	β-catenin mediates stress resilience through Dicer1/microRNA regulation.	DICER1 CTNNB1	1.24e-05	2	123	2	25383518
Pubmed	Nucleoporin 93, a new substrate of the E3 ubiquitin protein ligase HECTD1, promotes esophageal squamous cell carcinoma progression.	NUP93 HECTD1	1.24e-05	2	123	2	37993750
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	PSMA5 OBSL1 EXOSC8 CEP192 DICER1 PJA2 IGF2BP3 RUVBL1 ASPSCR1 HOOK2 HECTD1	1.78e-05	639	123	11	23443559
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	HECTD4 SRPK2 ZNF318 DICER1 RUVBL1 NUP93 CTNNB1 HECTD1 THAP12	2.82e-05	440	123	9	34244565
Pubmed	Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity.	PJA1 HTT	3.71e-05	3	123	2	34161122
Pubmed	Gene-dosage-sensitive genetic interactions between inversus viscerum (iv), nodal, and activin type IIB receptor (ActRIIB) genes in asymmetrical patterning of the visceral organs along the left-right axis.	NODAL DNAH11	3.71e-05	3	123	2	12112458
Pubmed	Adenovirus E1A binding to DCAF10 targets proteasomal degradation of RUVBL1/2 AAA+ ATPases required for quaternary assembly of multiprotein machines, innate immunity, and responses to metabolic stress.	RUVBL1 DCAF10	3.71e-05	3	123	2	37962355
Pubmed	Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes.	STAT1 IFNAR1	3.71e-05	3	123	2	10562320
Pubmed	Methyltransferase SETD2-Mediated Methylation of STAT1 Is Critical for Interferon Antiviral Activity.	STAT1 IFNAR1	3.71e-05	3	123	2	28753426
Pubmed	Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity.	SQLE IFNAR1	3.71e-05	3	123	2	38613784
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT3 FAT2	3.71e-05	3	123	2	15744052
Pubmed	Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor.	STAT1 IFNAR1	3.71e-05	3	123	2	22474018
Pubmed	Injury-induced type I IFN signaling regulates inflammatory responses in the central nervous system.	STAT1 IFNAR1	3.71e-05	3	123	2	20562259
Pubmed	Viruses evade the immune system through type I interferon-mediated STAT2-dependent, but STAT1-independent, signaling.	STAT1 IFNAR1	3.71e-05	3	123	2	15723812
Pubmed	Micro RNA-214 contributes to proteasome independent downregulation of beta catenin in Huntington's disease knock-in striatal cell model STHdhQ111/Q111.	CTNNB1 HTT	3.71e-05	3	123	2	25747711
Pubmed	Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.	ZFX ZNF711	3.71e-05	3	123	2	32406922
Pubmed	A type I IFN-Flt3 ligand axis augments plasmacytoid dendritic cell development from common lymphoid progenitors.	STAT1 IFNAR1	3.71e-05	3	123	2	24145513
Pubmed	IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.	STAT1 IFNAR1	3.71e-05	3	123	2	17227866
Pubmed	Type I interferons regulate cytolytic activity of memory CD8(+) T cells in the lung airways during respiratory virus challenge.	STAT1 IFNAR1	3.71e-05	3	123	2	20637658
Pubmed	Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling.	STAT1 CTNNB1	3.71e-05	3	123	2	37360690
Pubmed	Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment.	STAT1 IFNAR1	3.71e-05	3	123	2	32643603
Pubmed	Immune response in Stat2 knockout mice.	STAT1 IFNAR1	3.71e-05	3	123	2	11163195
Pubmed	The virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.	STAT1 IFNAR1	3.71e-05	3	123	2	21937652
Pubmed	Nodal signaling modulates the expression of Oct-4 via nuclear translocation of β-catenin in lung and prostate cancer cells.	CTNNB1 NODAL	3.71e-05	3	123	2	27592306
Pubmed	Obstructive Lymphangitis Precedes Colitis in Murine Norovirus-Infected Stat1-Deficient Mice.	STAT1 IFNAR1	3.71e-05	3	123	2	29753791
Pubmed	Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans.	ITGA3 CTNNB1	3.71e-05	3	123	2	23011394
Pubmed	Type I interferon limits mast cell-mediated anaphylaxis by controlling secretory granule homeostasis.	STAT1 IFNAR1	3.71e-05	3	123	2	31730616
Pubmed	Palmitoylation of interferon-alpha (IFN-alpha) receptor subunit IFNAR1 is required for the activation of Stat1 and Stat2 by IFN-alpha.	STAT1 IFNAR1	3.71e-05	3	123	2	19561067
Pubmed	Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells.	STAT1 IFNAR1	3.71e-05	3	123	2	31329638
Pubmed	Functional crosstalk between type I and II interferon through the regulated expression of STAT1.	STAT1 IFNAR1	3.71e-05	3	123	2	20436908
Pubmed	Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice.	STAT1 IFNAR1	3.71e-05	3	123	2	22479645
Pubmed	Critical roles for both STAT1-dependent and STAT1-independent pathways in the control of primary dengue virus infection in mice.	STAT1 IFNAR1	3.71e-05	3	123	2	16148142
Pubmed	Tyrosine kinase 2 controls IL-1ß production at the translational level.	STAT1 IFNAR1	3.71e-05	3	123	2	20713887
Pubmed	Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice.	STAT1 IFNAR1	3.71e-05	3	123	2	21915277
Pubmed	Proapoptotic and antiapoptotic actions of Stat1 versus Stat3 underlie neuroprotective and immunoregulatory functions of IL-11.	IL11RA STAT1	3.71e-05	3	123	2	21709156
Pubmed	Conditional Stat1 ablation reveals the importance of interferon signaling for immunity to Listeria monocytogenes infection.	STAT1 IFNAR1	3.71e-05	3	123	2	22719255
Pubmed	The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.	CTNNB1 HTT	3.71e-05	3	123	2	24960609
Pubmed	Distinct requirements for IFNs and STAT1 in NK cell function.	STAT1 IFNAR1	3.71e-05	3	123	2	11034357
Pubmed	Induction of IFN-alphabeta enables Listeria monocytogenes to suppress macrophage activation by IFN-gamma.	STAT1 IFNAR1	3.71e-05	3	123	2	20123961
Pubmed	Antiviral Functions of Type I and Type III Interferons in the Olfactory Epithelium.	STAT1 IFNAR1	3.71e-05	3	123	2	38136633
Pubmed	Alpha/beta interferons regulate murine gammaherpesvirus latent gene expression and reactivation from latency.	STAT1 IFNAR1	3.71e-05	3	123	2	16254350
Pubmed	PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain.	PJA2 PJA1	3.71e-05	3	123	2	12036302
Pubmed	Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus.	NODAL DNAH11	3.71e-05	3	123	2	8610013
Pubmed	THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer.	IGF2BP3 THADA	3.71e-05	3	123	2	28193878
Pubmed	Role for innate IFNs in determining respiratory syncytial virus immunopathology.	STAT1 IFNAR1	3.71e-05	3	123	2	15905569
Pubmed	The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.	STAT1 IFNAR1	3.71e-05	3	123	2	23273843
Pubmed	Cancer Stem Cells Regulate Cancer-Associated Fibroblasts via Activation of Hedgehog Signaling in Mammary Gland Tumors.	VCAN CTNNB1 IHH	4.01e-05	19	123	3	28202523
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CASP8AP2 INPPL1 OBSL1 ZNF318 CEP192 IGF2BP3 GPBP1L1 CTNNB1 CFAP44 ANKRD52	4.80e-05	588	123	10	38580884
Pubmed	Wnt3a links left-right determination with segmentation and anteroposterior axis elongation.	CTNNB1 NODAL DNAH11	5.48e-05	21	123	3	16291790
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	PSMA5 OBSL1 SRPK2 E4F1 ECPAS STAT1 SMYD2 CYFIP2 MACROH2A2 SPIDR CTNNB1 ANKRD52	5.48e-05	857	123	12	25609649
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	COBLL1 SARM1 BIRC6 THADA FAT2 TXNDC16 SPIDR HECTD1 UTP14C	6.78e-05	493	123	9	15368895
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	SARM1 OBSL1 EIF6 DICER1 STAT1 IRAK4 PJA1	6.97e-05	283	123	7	21903422
Pubmed	Type I IFN modulates innate and specific antiviral immunity.	STAT1 IFNAR1	7.41e-05	4	123	2	10754318
Pubmed	Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.	STAT1 IFNAR1	7.41e-05	4	123	2	19620292
Pubmed	Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis.	STAT1 IFNAR1	7.41e-05	4	123	2	23653476
Pubmed	Species-Specific Pathogenicity of Severe Fever with Thrombocytopenia Syndrome Virus Is Determined by Anti-STAT2 Activity of NSs.	STAT1 IFNAR1	7.41e-05	4	123	2	30814285
Pubmed	A genome-wide association study of neuroticism in a population-based sample.	PDE4D ARRDC4	7.41e-05	4	123	2	20634892
Pubmed	Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN-alpha/beta on antigen cross-presentation.	STAT1 IFNAR1	7.41e-05	4	123	2	17018853
Pubmed	IDO1+ Paneth cells promote immune escape of colorectal cancer.	STAT1 IFNAR1	7.41e-05	4	123	2	32444775
Pubmed	Stat1 and Stat2 but not Stat3 arbitrate contradictory growth signals elicited by alpha/beta interferon in T lymphocytes.	STAT1 IFNAR1	7.41e-05	4	123	2	15964802
Pubmed	STAT2 mediates innate immunity to Dengue virus in the absence of STAT1 via the type I interferon receptor.	STAT1 IFNAR1	7.41e-05	4	123	2	21379341
Pubmed	IFN-alpha activates Stat6 and leads to the formation of Stat2:Stat6 complexes in B cells.	STAT1 IFNAR1	7.41e-05	4	123	2	10490982
Pubmed	Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis.	CTNNB1 IHH	7.41e-05	4	123	2	12917489
Pubmed	STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis.	STAT1 IFNAR1	7.41e-05	4	123	2	14688355
Pubmed	The role of IFN in respiratory syncytial virus pathogenesis.	STAT1 IFNAR1	7.41e-05	4	123	2	11884466
Pubmed	Visualizing the Selectivity and Dynamics of Interferon Signaling In Vivo.	STAT1 IFNAR1	7.41e-05	4	123	2	31825834
Pubmed	SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism.	STAT1 IFNAR1	7.41e-05	4	123	2	20386712
Pubmed	Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.	STAT1 IFNAR1	7.41e-05	4	123	2	38743761
Pubmed	IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium.	STAT1 IFNAR1	7.41e-05	4	123	2	37153622
Pubmed	LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis.	LRRK2 IFNAR1	7.41e-05	4	123	2	32057291
Pubmed	Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity.	RUVBL1 CTNNB1	7.41e-05	4	123	2	11080158
GeneFamily	Yippee like family	YPEL3 YPEL2 YPEL1	1.14e-06	5	89	3	1130
GeneFamily	Abhydrolase domain containing	ABHD17A ABHD17C ABHD17B	1.66e-04	22	89	3	4
Coexpression	PEREZ_TP53_TARGETS	ESPN YPEL3 MXRA5 ACO1 KIF16B HECTD4 FRMD8 ZFYVE1 CEP164 CYFIP2 ABHD17C ADAMTS7 SLC16A14 NRK VCAN ASPSCR1 IHH CRAMP1 MINDY1 SEC14L5	7.99e-07	1201	123	20	M4391
Coexpression	GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN	COBLL1 PSMA5 SQLE DCLRE1B IGF2BP3 VCAN LRP11 NUP93	1.27e-06	167	123	8	M6699
Coexpression	GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_DN	ARRDC4 LRRK2 ZNF711 DCAF10 VCAN NUP93 SPIDR MINDY1	4.86e-06	200	123	8	M4828
Coexpression	GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP	ZNF142 PDE4D PSMA5 SQLE EIF6 ENY2 SLC16A6	4.28e-05	198	123	7	M9534
Coexpression	GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_UP	ISLR2 NUDT7 INPPL1 BAAT E4F1 ARR3 MACROH2A2	4.56e-05	200	123	7	M9342
Coexpression	GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP	ARRDC4 LRRK2 ECPAS LRRC8D NUP93 CTNNB1 MINDY1	4.56e-05	200	123	7	M6597
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	DENND4A ARRDC4 COBLL1 SQLE PRDM4 ZNF711 PJA2	1.12e-06	193	123	7	08696a99309f5b088692ddac8cca35413b5e810d
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ISLR2 HID1 RYR3 CYFIP2 HOOK2 ZG16	8.68e-06	173	123	6	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	megakaryocytic-Platelet\|World / Lineage and Cell class	GRHL1 IGF2BP3 RGS6 SMOX MINDY1 SEC14L5	1.09e-05	180	123	6	c007c3e63c2bb35ed34327dd8863899b5db93115
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 LRRC2 CYFIP2 ABHD17C NRK ARHGEF3	1.16e-05	182	123	6	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ESPN PDE4D KIF16B FAM135B CYFIP2 KCNK5	1.43e-05	189	123	6	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	356C-Myeloid-Monocyte-CD14+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PDE4D YPEL2 ABHD17C SLC16A6 VCAN CDC42EP2	1.66e-05	194	123	6	3f9ac1de8605a7930f49a7ce0e32aea9997d7791
ToppCell	356C-Myeloid-Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PDE4D YPEL2 ABHD17C SLC16A6 VCAN CDC42EP2	1.66e-05	194	123	6	a41cde3088b43670210daab4f43a24aa83dbd45b
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ISLR2 COBLL1 HID1 ITGA3 RGS6 ARHGEF3	1.81e-05	197	123	6	a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell	Control-Control-Others\|Control / Disease, condition lineage and cell class	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX SEC14L5	1.92e-05	199	123	6	b7e83772fdd466e1bd0ae13af9ac477e7595ae14
ToppCell	Control-Control-Others-Platelet\|Control / Disease, condition lineage and cell class	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX SEC14L5	1.97e-05	200	123	6	e0463c93714ab5fd00f294cca83bd61027fe0e95
ToppCell	Influenza-Influenza_Severe-Others-Platelet\|Influenza_Severe / Disease, condition lineage and cell class	MGAT4B GRHL1 RGS6 XIRP2 SMOX SEC14L5	1.97e-05	200	123	6	548e8e2f0e4225827db58b0c8b05221f18ae482b
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IL11RA ISLR2 GRM4 MAPK15 RGS6	6.07e-05	150	123	5	2ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 PDE4D COBLL1 STAT1 MAPK15	8.23e-05	160	123	5	7064af50fc10e3ea03badf415306222b74db0f95
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COBLL1 ITGA3 RYR3 NRK HECTD1	8.73e-05	162	123	5	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN PDE4D CYFIP2 TTLL12 LRP11	8.98e-05	163	123	5	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESPN PDE4D CYFIP2 TTLL12 LRP11	8.98e-05	163	123	5	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ISLR2 YPEL1 RYR3 GRHL1 MAPK15	1.04e-04	168	123	5	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAT3 CEP192 THADA ADAMTS7 WDR90	1.09e-04	170	123	5	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BTBD6 SQLE DCLRE1B CDC42EP2 KCNK5	1.09e-04	170	123	5	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DENND4A ZNF142 E4F1 PRDM4 BIRC6	1.19e-04	173	123	5	28c98a9a54aa2cfa67464db4f628c9357ad185b9
ToppCell	facs-MAT-Fat-3m-Epithelial-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SAMD7 GRHL1 DNAH11	1.29e-04	93	123	4	dbfaa7f23d25f5c286ab7ca3ca795b734cb95153
ToppCell	facs-MAT-Fat-3m-Epithelial-epithelial_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SAMD7 GRHL1 DNAH11	1.29e-04	93	123	4	0d6d1d8dd9c91ba31eb35a4b5979d087890936c1
ToppCell	facs-MAT-Fat-3m-Epithelial\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 SAMD7 GRHL1 DNAH11	1.29e-04	93	123	4	abffb1fd5a919b7c08e62e1c3c08a8dd8783a4ca
ToppCell	NS-critical-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ITGA3 MAPK15 LRP11 CFAP44 DNAH11	1.29e-04	176	123	5	b794275fdd757b8fa2108e3c867f23da2649146d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAPK15 LRP11 WDR90 CFAP44 DNAH11	1.43e-04	180	123	5	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ESPN MAPK15 WDR90 CFAP44 DNAH11	1.43e-04	180	123	5	92fb01b91261b3103454924cde56add337b41844
ToppCell	3'_v3-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	OBSL1 RYR3 ACSM4 RGS6 IHH	1.47e-04	181	123	5	30ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell	Influenza_Severe-Platelet\|Influenza_Severe / Disease group and Cell class	GRHL1 RGS6 XIRP2 SMOX SEC14L5	1.47e-04	181	123	5	4d037b098bb6f780ed8b15c0ec23a6f4d86bf45a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 PDE4D COBLL1 M1AP SLC16A14	1.47e-04	181	123	5	b7c85fbef3c06d5dc32a2a58f8d3dfabf1d79d9f
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ESPN DENND4A HECTD4 LRRC2 ZFYVE1	1.51e-04	182	123	5	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	YPEL3 HECTD4 ZFX THADA MACROH2A2	1.51e-04	182	123	5	21744c9c792e57d5d41b25986f419b2358c7057b
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|bone_marrow / Manually curated celltypes from each tissue	IGF2BP3 RGS6 SMOX MINDY1 SEC14L5	1.54e-04	183	123	5	3cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRDC4 LRRC2 ITGA3 RYR3 ARHGEF3	1.54e-04	183	123	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 RYR3 XIRP2 NRK DNAH11	1.58e-04	184	123	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MGAT4B GRHL1 RGS6 SMOX SEC14L5	1.58e-04	184	123	5	a5d904dd030d9c21be0f8b9ec432025f90fb5b8e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC8 LRRC2 MAPK15 SCG3 CFAP44	1.58e-04	184	123	5	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDAC8 LRRC2 MAPK15 SCG3 CFAP44	1.58e-04	184	123	5	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 RYR3 XIRP2 NRK DNAH11	1.58e-04	184	123	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CASP8AP2 ZNF318 DCLRE1B ECPAS HTT	1.58e-04	184	123	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 RYR3 XIRP2 NRK DNAH11	1.58e-04	184	123	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MGAT4B GRHL1 RGS6 SMOX SEC14L5	1.58e-04	184	123	5	7617a00b2ebd6c5c9386c39a7e8220fdbf8669ff
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GRHL1 IGF2BP3 RGS6 SMOX MINDY1	1.67e-04	186	123	5	107bc473f5e57238390f8e0ab9f7263a8f93948c
ToppCell	PBMC-Control-Hematopoietic-Platelet\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX	1.67e-04	186	123	5	9c2fd0bbc968c317a763f52e72fa7182c3c49850
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GRHL1 IGF2BP3 RGS6 SMOX MINDY1	1.67e-04	186	123	5	13a9ddcf93b0c4319ab9d484af5e2056e9754caa
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX	1.67e-04	186	123	5	06281df5e9665ccc510279bf7e552845c63d5dab
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-1\|TCGA-Breast / Sample_Type by Project: Shred V9	SRPK2 SLC16A6 TXNDC16 MINDY1 HTT	1.71e-04	187	123	5	a716b64ca03d9b61da765bf87f065ac9393303f1
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	PDE4D COBLL1 LRRK2 ABHD17C GRHL1	1.71e-04	187	123	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Control-Hematopoietic_Mega-Platelet\|Control / Disease group, lineage and cell class	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX	1.71e-04	187	123	5	53e9665e1feb02ce8fe78ff4128fd4beacef8471
ToppCell	droplet-Pancreas\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYFIP2 MAPK15 SCG3 LRP11 ZG16	1.71e-04	187	123	5	5f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCell	severe-Platelet\|World / disease stage, cell group and cell class	GRHL1 RGS6 XIRP2 SMOX MINDY1	1.71e-04	187	123	5	72475fb6d053354b581e61c6eee3719a7dd08c8b
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARRDC4 LRRC2 ITGA3 RYR3 ARHGEF3	1.71e-04	187	123	5	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	Control-Hematopoietic_Mega\|Control / Disease group, lineage and cell class	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX	1.71e-04	187	123	5	7bf98bdc83feb3918dbcf12e87a64fe4d2d41eba
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DENND4A AHCTF1 BIRC6 TASOR2 CTNNB1	1.75e-04	188	123	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PBMC-Mild-Hematopoietic\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.75e-04	188	123	5	e3d9919eafc6181d2145b9d36f47066d0e22a8bd
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	LRRC2 SMYD2 RGS6 XIRP2 HOOK2	1.75e-04	188	123	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	Control-Myeloid-cMonocyte\|Myeloid / Disease state, Lineage and Cell class	PDE4D LRRK2 ABHD17C VCAN CDC42EP2	1.75e-04	188	123	5	47126c371a242c937499fd278a74a882df8f759c
ToppCell	PBMC-Mild-Hematopoietic\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.75e-04	188	123	5	6bd9317be8918da639254f4bdd432647c43ba9b1
ToppCell	severe_influenza-Platelet\|World / disease group, cell group and cell class (v2)	MGAT4B RGS6 XIRP2 SMOX SEC14L5	1.75e-04	188	123	5	b54632baa682aaf51100d44e7f114a54d5edd695
ToppCell	mild_COVID-19-Platelet\|World / disease group, cell group and cell class (v2)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.80e-04	189	123	5	038ec3c266b89416bb5b774ba522d916394961da
ToppCell	356C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	COBLL1 HID1 SAMD7 SLC16A14 SMOX	1.80e-04	189	123	5	0994aba7a44577a8943af237c9c3575502d0584c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MXRA5 PDE4D COBLL1 M1AP SLC16A14	1.80e-04	189	123	5	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	356C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	COBLL1 HID1 SAMD7 SLC16A14 SMOX	1.80e-04	189	123	5	d1bd3b5ac32459929e556fb3a4fe8e1e15f6e658
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D COBLL1 ITGA3 NRK HECTD1	1.80e-04	189	123	5	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	PDE4D LRRC2 SMYD2 XIRP2 HOOK2	1.80e-04	189	123	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Healthy-Platelet\|World / disease group, cell group and cell class	MGAT4B GRHL1 IGF2BP3 RGS6 SMOX	1.80e-04	189	123	5	c3d8e3682cb489bca887039cbea6c4cfc264de2f
ToppCell	PBMC-Mild-Hematopoietic-Platelet\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.84e-04	190	123	5	726aeb280ea911f3551b18e388c4f7580ae2ea74
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.84e-04	190	123	5	50ea3ff7ba1ca335b4e4538fae5f9b74b1fc10f7
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.84e-04	190	123	5	a1f8757dc719ed030f67d65735358a8d7a407bad
ToppCell	PBMC-Mild-Hematopoietic-Platelet\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.84e-04	190	123	5	c4f55f5a0c42aeb571791925ea80e02fac320608
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGF2BP3 RGS6 SMOX MINDY1 SEC14L5	1.88e-04	191	123	5	b9070e62e28e818631e2bbb48e097d1307777a5c
ToppCell	mild_COVID-19-Platelet\|mild_COVID-19 / disease group, cell group and cell class (v2)	IGF2BP3 RGS6 XIRP2 SMOX MINDY1	1.88e-04	191	123	5	968e2d48969884dd21b8a87f199af94a7410b0dd
ToppCell	Healthy_donor-Platelet\|World / disease group, cell group and cell class (v2)	MGAT4B GRHL1 RGS6 SMOX MINDY1	1.88e-04	191	123	5	defae87313d6345e3f451250fd66fe8831bb441c
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGF2BP3 RGS6 SMOX MINDY1 SEC14L5	1.88e-04	191	123	5	960e0267786794454acbc77ddc766fd5dce99820
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MGAT4B IGF2BP3 RGS6 SMOX MINDY1	1.93e-04	192	123	5	f48202c271c9233c78de255a2fa131b219f688d7
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MGAT4B IGF2BP3 RGS6 SMOX MINDY1	1.93e-04	192	123	5	35ae787e90e7e5e333978125e19de1590316c769
ToppCell	COVID-19-kidney-CNT\|kidney / Disease (COVID-19 only), tissue and cell type	MXRA5 PDE4D COBLL1 RGS6 ARHGEF3	1.93e-04	192	123	5	d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D COBLL1 SQLE ITGA3 HECTD1	1.93e-04	192	123	5	2510f22197502f60fd266b7f42eff040f25b8ae7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PDE4D COBLL1 SQLE ITGA3 HECTD1	1.93e-04	192	123	5	e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MGAT4B IGF2BP3 RGS6 SMOX MINDY1	1.93e-04	192	123	5	3276bd4f1023a020ebb26ec33424b6e9897d31c9
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MGAT4B IGF2BP3 RGS6 SMOX MINDY1	1.93e-04	192	123	5	9ae14279e9b91e04ea2c5bbbeadb111a1b966bd1
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DENND4A HECTD4 LRRC2 GRHL1 SMOX	1.98e-04	193	123	5	305e15ee467826ee08b2617c69f250ad39c11b19
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ESPN DENND4A HECTD4 LRRC2 PKD1L3	1.98e-04	193	123	5	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	DENND4A HECTD4 LRRC2 GRHL1 SMOX	1.98e-04	193	123	5	dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAPK15 LRP11 WDR90 CFAP44 DNAH11	2.07e-04	195	123	5	79dc031258579ea328181dda33710dd897f1064a
ToppCell	Sepsis-ICU-SEP-Myeloid-cDC1\|ICU-SEP / Disease, condition lineage and cell class	KIF16B OBSL1 ZNF318 ZNF711 CNDP1	2.18e-04	197	123	5	e3174e90ea6136f1aa3a4a185b86458e35d51fd4
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MXRA5 FAT3 RYR3 RGS6 VCAN	2.18e-04	197	123	5	467e7cbf511d3bcc701923603032aaf0bba2736d
ToppCell	control-Platelet\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MGAT4B GRHL1 IGF2BP3 SMOX SEC14L5	2.23e-04	198	123	5	1a4b604ef25bd066e870c0d00ee31cde9617f125
ToppCell	severe-Platelet\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MGAT4B IGF2BP3 XIRP2 SMOX SEC14L5	2.28e-04	199	123	5	6539c197c653fce083a893ac422263abbbc07e79
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SARM1 HID1 PLEKHG2 TTLL12 MINDY1	2.33e-04	200	123	5	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	MS-Multiple_Sclerosis-Others-Platelet\|Multiple_Sclerosis / Disease, condition lineage and cell class	AHCTF1 IGF2BP3 RGS6 XIRP2 SMOX	2.33e-04	200	123	5	263d956136747c209951b4358f2e1672a21d8eef
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|390C / Donor, Lineage, Cell class and subclass (all cells)	CEP192 DCLRE1B ZFYVE1 TXNDC16	2.54e-04	111	123	4	dfbdeadad321392d359e6fb7112b28b043a4b874
Disease	cold shock domain-containing protein E1 measurement	SARM1 ARHGEF3	4.74e-05	3	118	2	EFO_0802416
Disease	myocyte-specific enhancer factor 2C measurement	SARM1 ARHGEF3	4.74e-05	3	118	2	EFO_0802770
Disease	intersectin-1 measurement	SARM1 ARHGEF3	4.74e-05	3	118	2	EFO_0801733
Disease	calcium-binding and coiled-coil domain-containing protein 2 measurement	SARM1 ARHGEF3	9.46e-05	4	118	2	EFO_0802356
Disease	ephrin-B1 measurement	SARM1 PJA1	9.46e-05	4	118	2	EFO_0021930
Disease	MAGUK p55 subfamily member 7 measurement	SARM1 ARHGEF3	9.46e-05	4	118	2	EFO_0802724
Disease	leukemia inhibitory factor measurement	SARM1 SMOX	9.46e-05	4	118	2	EFO_0801764
Disease	lysozyme-like protein 2 measurement	SARM1 ARHGEF3	1.57e-04	5	118	2	EFO_0801779
Disease	n-acetylserotonin O-methyltransferase-like protein measurement	SARM1 ARHGEF3	2.35e-04	6	118	2	EFO_0801818
Disease	ribonucleoside-diphosphate reductase subunit M2 B measurement	SARM1 ARHGEF3	3.29e-04	7	118	2	EFO_0802022
Disease	osteosarcoma	GRM4 TASOR2	4.37e-04	8	118	2	EFO_0000637
Disease	dynein light chain roadblock-type 1 measurement	SARM1 ARHGEF3	4.37e-04	8	118	2	EFO_0008114
Disease	Endometrioma	LRRK2 DICER1 SLC16A6 VCAN IHH	4.84e-04	161	118	5	C0269102
Disease	Endometriosis	LRRK2 DICER1 SLC16A6 VCAN IHH	4.84e-04	161	118	5	C0014175
Disease	interferon alpha/beta receptor 1 measurement	SARM1 IFNAR1	5.60e-04	9	118	2	EFO_0021850
Disease	subiculum volume	ARRDC4 VCAN LRP11	6.85e-04	43	118	3	EFO_0009399
Disease	non-receptor tyrosine-protein kinase TYK2 measurement	SARM1 ARHGEF3	6.99e-04	10	118	2	EFO_0008251
Disease	Peritoneal Neoplasms	IGF2BP3 CTNNB1	6.99e-04	10	118	2	C0031149
Disease	Carcinomatosis of peritoneal cavity	IGF2BP3 CTNNB1	6.99e-04	10	118	2	C0346990
Disease	metachronous colorectal adenoma	PDE4D FAT3 HOOK2	7.83e-04	45	118	3	EFO_0803377
Disease	apolipoprotein B measurement	COBLL1 PSMA5 SARM1 PKD1L3 THADA KCNK5 NUP93 HTT DNAH11	1.41e-03	663	118	9	EFO_0004615
Disease	amino acid measurement	PDE4D ARRDC4 COBLL1 RYR3 M1AP GRHL1 VCAN TXNDC16 HTT	1.64e-03	678	118	9	EFO_0005134
Disease	sphingomyelin 14:0 measurement	PDE4D THADA	2.07e-03	17	118	2	EFO_0010390
Disease	neurodegenerative disease (implicated_via_orthology)	PSMA5 SARM1 LRRK2 HTT	2.78e-03	145	118	4	DOID:1289 (implicated_via_orthology)
Disease	Deaf Mutism	ESPN SERAC1	2.87e-03	20	118	2	C4082305
Disease	Deafness, Acquired	ESPN SERAC1	2.87e-03	20	118	2	C0751068
Disease	Hearing Loss, Extreme	ESPN SERAC1	2.87e-03	20	118	2	C0086395
Disease	Complete Hearing Loss	ESPN SERAC1	2.87e-03	20	118	2	C0581883
Disease	Bilateral Deafness	ESPN SERAC1	2.87e-03	20	118	2	C3665473
Disease	Prelingual Deafness	ESPN SERAC1	2.87e-03	20	118	2	C0011052
Disease	myocardial infarction	HECTD4 DCLRE1B PKD1L3 THADA KCNK5 HTT	2.89e-03	350	118	6	EFO_0000612
Disease	cognitive function measurement, self reported educational attainment	DENND4A PDE4D SRPK2 PKD1L3 BIRC6 SCG3	3.10e-03	355	118	6	EFO_0004784, EFO_0008354
Disease	reticulocyte count	DENND4A COBLL1 HECTD4 BIRC6 EIF6 STAT1 THADA DCAF10 HOOK2 ARHGEF3 SMOX	3.18e-03	1045	118	11	EFO_0007986
Disease	uric acid measurement	FAT3 COBLL1 HECTD4 FRMD8 ZNF318 BIRC6 KCNK5 ANKRD52	3.19e-03	610	118	8	EFO_0004761
Disease	psoriasis, type 2 diabetes mellitus	COBLL1 THADA ANKRD52	3.41e-03	75	118	3	EFO_0000676, MONDO_0005148
Disease	carnitine measurement	ZNF318 STRIP1 NRK	3.54e-03	76	118	3	EFO_0010469
Disease	mean arterial pressure	YPEL2 HECTD4 ZNF318 ABHD17C THADA RGS6 ARHGEF3	4.00e-03	499	118	7	EFO_0006340

Protein segments in the cluster

Peptide	Gene	Start	Entry
TIHLPSGEILDVFDA	ACO1	741	P21399
LHLVVAGLDSEPVIE	BTN2A3P	136	Q96KV6
HVTVDDLVAEITPKG	ENY2	61	Q9NPA8
ALVDEPVHIRATGLI	BAAT	11	Q14032
LLEHAISPSAADVLV	ASPSCR1	476	Q9BZE9
IFGTLDSLIPLHEEL	ARHGEF3	166	Q9NR81
LLETIDEPLTHDITG	BIRC6	2456	Q9NR09
HPEAVGDASLTVVKL	VCAN	106	P13611
GDLAEVKSEIHIPDV	BTBD6	171	Q96KE9
SKIAPVLHLEEVAEG	GRM4	316	Q14833
VHPTTAEIDLKEDIG	MACROH2A2	216	Q9P0M6
LGHVSAFLDEILVPV	DNAH11	156	Q96DT5
PVLIIHGTEDEVIDF	ABHD17A	246	Q96GS6
EVESALIEHPAVVES	ACSM4	486	P0C7M7
TVLAVDEEGHTPALA	ANKRD52	986	Q8NB46
PGKLHVEVSADLTAI	DICER1	1161	Q9UPY3
VPSISEHILGEAAVS	CASP8AP2	606	Q9UKL3
ALEVGESHVLPLDEI	DCLRE1B	71	Q9H816
PLESDTIVVHAILSD	CFAP44	1026	Q96MT7
GTLIIHSEDPLTVKD	COBLL1	661	Q53SF7
HVDTVEPIDGVVLVD	ARR3	26	P36575
TASDVGVELPLVLIH	ARR3	336	P36575
EDTGLPLAFTVAHEL	ADAMTS7	376	Q9UKP4
ETVAGHVLLEASEPV	ARRDC4	36	Q8NCT1
PHVFELGVIALDVAE	ISLR2	481	Q6UXK2
GVVLDSELPHLIGID	KIF16B	446	Q96L93
LAAETEGISELPHVE	NUP93	16	Q8N1F7
AGLTDVSKPLEEEIH	DENND4A	16	Q7Z401
EDPVEAIHLGSLIAA	RGS6	76	P49758
LIVDPTGEEEHLATG	EXOSC8	206	Q96B26
HLVPTARLVAGLEDV	OBSL1	611	O75147
KLVSELTPLTVHEGD	OBSL1	1361	O75147
IEAEGATAPLTELLH	CTNNB1	631	P35222
LEEVITDAVAGLPHA	IL11RA	276	Q14626
QDVVLHLPTDGVVLD	LRP11	216	Q86VZ4
GILEHVDSASPVEDT	M1AP	181	Q8TC57
ALFPTEIHSGLLEVI	MGAT4B	201	Q9UQ53
ALPVVEEGEVLSHSL	GPBP1L1	371	Q9HC44
EFGDHPNIISLLDVI	MAPK15	66	Q8TD08
PVSVAISLEGVHVID	FRMD8	291	Q9BZ67
VSEEHLPDVSLIGEF	HOOK2	91	Q96ED9
GVQLDVEALIPTHDE	ESPN	731	B1AK53
VPELEAVLHLVIASS	ECPAS	256	Q5VYK3
EAEDKAIVIHISPGT	IFNAR1	136	P17181
DEHILEVTVLDNGEP	FAT2	1206	Q9NYQ8
SGEDAHEALLTLVVP	ITGA3	666	P26006
LAIGAAIFEVLEEPH	KCNK5	16	O95279
SIASDIHGDDLIVTP	PDE4D	211	Q08499
IHGDDLIVTPFAQVL	PDE4D	216	Q08499
LEVVTPEVLGESDHG	DCAF10	396	Q5QP82
TAEAVIPENHEVLAG	MINDY1	16	Q8N5J2
TLLVVSGDHLVELPT	LRRC2	286	Q9BYS8
PVILVGTHLDVSDEK	LRRK2	1446	Q5S007
VDHIDSLIGFPEQIA	LRRC42	101	Q9Y546
PSSIEKIVEIDAHIG	PSMA5	61	P28066
DTDTLITPFVGLIDH	NUDT7	116	P0C024
SSLDGPIVLAIEDFH	CYFIP2	606	Q96F07
LLVISGIPTHLDEGV	HECTD4	2976	Q9Y4D8
ETVHLFIPALSVGAI	IGF2BP3	406	O00425
DVVDIAGEEHLPVLV	THAP12	266	O43422
ELSDTIPVVHASIAG	EIF6	41	P56537
IVSGADVHEPIVVLS	HECTD1	1416	Q9ULT8
LGLLVPVEDEHSTLL	HTT	296	P42858
PVEDEHSTLLILGVL	HTT	301	P42858
THVLPIASEELEGEG	GRHL1	486	Q9NZI5
LSLHVDLGPSILDDV	CDC42EP2	181	O14613
EVLPEHVSVLQGVDL	EPM2AIP1	131	Q7L775
GEPATHISDSIIEIA	CRAMP1	1091	Q96RY5
GDIKELHAPLTVVAD	SQLE	271	Q14534
VGELSLASLHIPFVE	FAT3	4536	Q8TDW7
SPVLVIHGTEDEVID	ABHD17C	266	Q6PCB6
LLKPGEEHEVIVSFT	CEP192	1701	Q8TEP8
VLLEIITGLPAVDEH	IRAK4	376	Q9NWZ3
DLEVLTGIPAEVPHI	AHCTF1	186	Q8WYP5
ILEHAGELVIASPEG	E4F1	761	Q66K89
TDAGADHPLVEIVLD	FAM135B	821	Q49AJ0
VILGKTLSSEIPDHE	HDAC8	321	Q9BY41
APHEVAVEILEGESV	SEC14L5	521	O43304
PLTKHGTLVVEDVVA	IHH	331	Q14623
SGLVVEDHLFDTLPL	LRRC8D	826	Q7L1W4
SLHEVGLSLEPVAVS	PRDM4	316	Q9UKN5
GTHIPLLAEDDVVGI	SLC16A6	401	O15403
LDHKPVTVDLAIGSE	NRK	1406	Q7Z2Y5
LHETVAPSDIVAAGV	SLC35G3	301	Q8N808
LHVVPVESADLGIGD	SERAC1	601	Q96JX3
LTILGSIAEVFHVPE	THADA	756	Q6YHU6
EGPLIVTEELHSLSF	STAT1	421	P42224
DHAIDGETLPLLTEE	SAMD7	351	Q7Z3H4
EPLSEDTIAGLSVHV	HPS3	881	Q969F9
VDLPTEGSLAIEIFH	NODAL	101	Q96S42
PVVTEDLVGIEHLAN	SLC16A14	426	Q7RTX9
IPVFTGTHADLLIVV	HID1	451	Q8IV36
GISHQEEVFALDPVL	PKD1L3	1636	Q7Z443
VHELPELTAESLEAG	STRIP1	641	Q5VSL9
LGKTLDEVTVTIPHD	INPPL1	451	O15357
PVLIIHGTEDEVIDF	ABHD17B	226	Q5VST6
EHLLDVDVLSPVLGG	CEP164	421	Q9UPV0
VHKSVVLIPLGAVDD	CNDP1	461	Q96KN2
VIAGHILDISDSPKE	XIRP2	3286	A4UGR9
PAEERVLLTGLHAVA	YPEL1	61	O60688
AEEGVPVEFLVLHDV	TXNDC16	326	Q9P2K2
VLLEAEHEGPVSSVC	WDR90	651	Q96KV7
EGGTEVEELLVPHVA	UTP14C	346	Q5TAP6
EPVELARSVAGILEH	SARM1	176	Q6SZW1
TAHPTSCIGLEEIEL	SPIDR	891	Q14159
ILLLIDPSVFGEHSA	RYR3	1746	Q15413
EDHIAHIIELLGSIP	SRPK2	596	P78362
ELIPADHVIVTVSLG	SMOX	321	Q9NWM0
AHVASLEGLIPEDKV	nan	51	A6NDN8
EGPIIIHTDEADSEV	ACP6	186	Q9NPH0
IEFHGELPSTEAVAL	TTLL12	151	Q14166
IAELVPGVLFVDEVH	RUVBL1	291	Q9Y265
DPVHKVAVIDTEGLL	ZFYVE1	226	Q9HBF4
PAEERVLLTGLHAVA	YPEL2	61	Q96QA6
GDLEEIFLHPGESVI	ZG16	81	O60844
IVESEPENDHGVELL	ZFX	271	P17010
PLHVLEGLESSIAAE	PLEKHG2	611	Q9H7P9
ILEVSTALDLLAEHP	TASOR2	271	Q5VWN6
HLEALGVELESVTEP	ZNF142	696	P52746
IEDEELSHLGSAIFP	SMYD2	186	Q9NRG4
IDGDHIVVSVPEAVL	ZNF711	36	Q9Y462
LAAEVVHGPDIITET	ZNF711	66	Q9Y462
ALPEILVTEDHGAVG	PJA1	576	Q8NG27
SGEDLIFHPVSVLVL	UHRF1BP1	1181	Q6BDS2
ESIDGLPETLVLEDH	PJA2	611	O43164
ELHQDEGLVAAPIVS	ZNF318	1626	Q5VUA4
LDGTPLTAEDIVHKI	SCG3	141	Q8WXD2
PDIHITVSEGASLEL	TRAV8-3	26	A0A0A6YYJ7
PAEERVLLTGLHAVA	YPEL3	61	P61236
SSADVPLLGEEEHVL	MXRA5	841	Q9NR99