Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR2M2 MRGPRD OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 ADGRV1 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 FZD9 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 FZD10 MRGPRX4 ADGRF4 OR2Z1 OR5L2 OR4X1 OR6B2	6.73e-22	884	104	35	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	1.11e-20	431	104	26	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR2M2 MRGPRD OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 ADGRV1 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 FZD9 BMPR1A ZACN OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 FZD10 CD72 MRGPRX4 ADGRF4 GRIN3A OR2Z1 OR5L2 OR4X1 OR6B2	1.24e-19	1353	104	39	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR6B3 OR10W1 OR5L2 OR6B2	2.11e-08	127	104	9	GO:0005549
GeneOntologyMolecularFunction	transporter activity	TRPC4AP XKR9 KCNK12 ANKH SLC2A10 ZACN SLC13A4 KCND2 SLC34A1 SLC15A4 CD36 NPC1L1 SLC7A5 MPC1 GRIN3A TMCO1 SLC14A2 SVOP	1.11e-04	1289	104	18	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	TRPC4AP KCNK12 ANKH SLC2A10 ZACN SLC13A4 KCND2 SLC34A1 SLC15A4 CD36 SLC7A5 MPC1 GRIN3A TMCO1 SLC14A2 SVOP	3.87e-04	1180	104	16	GO:0022857
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ANKH SLC2A10 SLC15A4 CD36 SLC7A5 MPC1 GRIN3A	8.61e-04	293	104	7	GO:0008514
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	2.35e-21	432	101	26	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	1.50e-20	465	101	26	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	4.29e-20	485	101	26	GO:0050907
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 CD36 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	6.11e-20	547	101	27	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	2.93e-19	524	101	26	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 ADGRV1 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	3.00e-19	582	101	27	GO:0050906
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	ZDHHC21 OR2M2 MRGPRD OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 ADGRV1 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 FZD9 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 FZD10 MRGPRX4 ADGRF4 OR2Z1 OR5L2 OR4X1 OR6B2 HTT	2.56e-18	1395	101	37	GO:0007186
GeneOntologyBiologicalProcess	detection of stimulus	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 ADGRV1 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	6.37e-18	722	101	28	GO:0051606
GeneOntologyBiologicalProcess	sensory perception	CYP4V2 OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 ADGRV1 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 KCND2 CD36 PGAP1 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	2.91e-16	1072	101	31	GO:0007600
GeneOntologyBiologicalProcess	regulation of bone mineralization	ADGRV1 ANKH FZD9 FGF23 BMP4 BMPR1A	5.65e-06	91	101	6	GO:0030500
GeneOntologyBiologicalProcess	regulation of biomineral tissue development	ADGRV1 ANKH FZD9 FGF23 BMP4 BMPR1A	2.06e-05	114	101	6	GO:0070167
GeneOntologyBiologicalProcess	pharyngeal arch artery morphogenesis	BMP4 BMPR1A ADGRF4	3.15e-05	13	101	3	GO:0061626
GeneOntologyBiologicalProcess	response to sodium phosphate	ANKH FGF23 SLC34A1	3.15e-05	13	101	3	GO:1904383
GeneOntologyBiologicalProcess	regulation of ossification	ADGRV1 ANKH FZD9 FGF23 BMP4 BMPR1A	8.59e-05	147	101	6	GO:0030278
GeneOntologyBiologicalProcess	bone mineralization	ADGRV1 ANKH FZD9 FGF23 BMP4 BMPR1A	9.26e-05	149	101	6	GO:0030282
GeneOntologyBiologicalProcess	positive regulation of bone mineralization	ADGRV1 FZD9 BMP4 BMPR1A	9.69e-05	49	101	4	GO:0030501
GeneOntologyBiologicalProcess	L-histidine transport	SLC15A4 SLC7A5	1.42e-04	4	101	2	GO:1902024
GeneOntologyBiologicalProcess	histidine transport	SLC15A4 SLC7A5	1.42e-04	4	101	2	GO:0015817
GeneOntologyBiologicalProcess	phosphate ion homeostasis	ANKH FGF23 SLC34A1	1.88e-04	23	101	3	GO:0055062
GeneOntologyBiologicalProcess	positive regulation of biomineral tissue development	ADGRV1 FZD9 BMP4 BMPR1A	2.14e-04	60	101	4	GO:0070169
GeneOntologyBiologicalProcess	inorganic diphosphate transport	ANKH SLC34A1	2.35e-04	5	101	2	GO:0030505
GeneOntologyBiologicalProcess	positive regulation of ossification	ADGRV1 FZD9 BMP4 BMPR1A	3.09e-04	66	101	4	GO:0045778
GeneOntologyBiologicalProcess	response to salt	ANKH FGF23 SLC34A1	3.42e-04	28	101	3	GO:1902074
GeneOntologyBiologicalProcess	phosphate ion transport	ANKH FGF23 SLC34A1	4.64e-04	31	101	3	GO:0006817
GeneOntologyBiologicalProcess	biomineral tissue development	ADGRV1 ANKH FZD9 FGF23 BMP4 BMPR1A	4.92e-04	203	101	6	GO:0031214
Domain	Olfact_rcpt	OR2M2 OR2T35 OR9I1 OR10J3 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	8.62e-19	393	102	24	IPR000725
Domain	7tm_1	OR2M2 MRGPRD OR2T35 OR9I1 OR10J3 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 MRGPRX4 OR2Z1 OR5L2 OR4X1 OR6B2	1.85e-18	677	102	29	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2M2 MRGPRD OR2T35 OR9I1 OR10J3 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 MRGPRX4 OR2Z1 OR5L2 OR4X1 OR6B2	2.54e-18	685	102	29	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2M2 MRGPRD OR2T35 OR9I1 OR10J3 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 MRGPRX4 OR2Z1 OR5L2 OR4X1 OR6B2	3.21e-18	691	102	29	PS50262
Domain	GPCR_Rhodpsn	OR2M2 MRGPRD OR2T35 OR9I1 OR10J3 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 MRGPRX4 OR2Z1 OR5L2 OR4X1 OR6B2	3.34e-18	692	102	29	IPR000276
Domain	GPCR_Rhodpsn_7TM	OR2M2 MRGPRD OR2T35 OR9I1 OR10J3 TAAR2 OR5K4 OR5K3 GPR52 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 HRH2 MRGPRX4 OR2Z1 OR5L2 OR4X1 OR6B2	1.54e-17	670	102	28	IPR017452
Domain	FAM209	FAM209A FAM209B	2.95e-05	2	102	2	IPR027943
Domain	FAM209	FAM209A FAM209B	2.95e-05	2	102	2	PF15206
Domain	DMAP_binding	DIP2B DIP2C	2.92e-04	5	102	2	PF06464
Domain	GPCR_2_secretin-like	ADGRV1 FZD9 FZD10 ADGRF4	3.23e-04	60	102	4	IPR000832
Domain	GPCR_2-like	ADGRV1 FZD9 FZD10 ADGRF4	3.23e-04	60	102	4	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRV1 FZD9 FZD10 ADGRF4	3.45e-04	61	102	4	PS50261
Domain	DMAP1-bd	DIP2B DIP2C	4.37e-04	6	102	2	IPR010506
Domain	DMAP_binding	DIP2B DIP2C	4.37e-04	6	102	2	SM01137
Domain	Frizzled	FZD9 FZD10	1.57e-03	11	102	2	IPR000539
Domain	Frizzled	FZD9 FZD10	1.57e-03	11	102	2	PF01534
Domain	XK_rel	XKR9 XKR7	1.57e-03	11	102	2	IPR018629
Domain	MRGPCRFAMILY	MRGPRD MRGPRX4	1.57e-03	11	102	2	IPR026234
Domain	XK-related	XKR9 XKR7	1.57e-03	11	102	2	PF09815
Domain	Frizzled	FZD9 FZD10	1.57e-03	11	102	2	SM01330
Domain	7TM_GPCR_Srsx	OR2M2 TAAR2 OR6F1 HRH2	3.32e-03	112	102	4	SM01381
Domain	Frizzled/SFRP	FZD9 FZD10	3.37e-03	16	102	2	IPR015526
Domain	FRI	FZD9 FZD10	5.26e-03	20	102	2	SM00063
Domain	-	FZD9 FZD10	5.80e-03	21	102	2	1.10.2000.10
Domain	MFS_dom	UNC93A SLC2A10 SLC15A4 SVOP	6.26e-03	134	102	4	IPR020846
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	1.44e-20	417	80	26	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	CYP4V2 OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR2T2 OR6C65 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	4.36e-17	636	80	27	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2M2 OR9I1 OR10J3 OR2T2 OR6C65 OR2T4 OR2T11 OR1F1 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	4.33e-12	389	80	18	M14091
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR6C65 OR2T4 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR6B2	1.20e-24	340	105	23	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR6C65 OR2T4 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR6B2	1.20e-24	340	105	23	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR6C65 OR2T4 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR6B2	1.46e-24	343	105	23	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2M2 OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR5K4 OR5K3 OR6C65 OR2T4 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2T6 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR6B2	1.79e-24	346	105	23	14611657
Pubmed	The human olfactory receptor gene family.	OR2T35 OR11H7 OR9I1 OR10J3 OR4E1 OR2T2 OR2T4 OR2T11 OR6P1 OR1F1 OR10G6 OR6F1 OR6B3 OR2AT4 OR52N2 OR10W1 OR52N5 OR2Z1 OR5L2 OR4X1 OR6B2	1.39e-17	541	105	21	14983052
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR2M2 OR11H7 OR9I1 OR10J3 OR4E1 OR2T2 OR1F1 OR6F1 OR2T6 OR2Z1 OR5L2	7.12e-11	219	105	11	12213199
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR2T35 OR9I1 OR10J3 OR4E1 OR2T4 OR52N2 OR2Z1	2.84e-09	74	105	7	15081110
Pubmed	Association of BMPR1A polymorphism, but not BMP4, with kidney size in full-term newborns.	BMP4 BMPR1A	9.03e-06	2	105	2	22886282
Pubmed	A striatal-enriched intronic GPCR modulates huntingtin levels and toxicity.	GPR52 HTT	9.03e-06	2	105	2	25738228
Pubmed	Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models.	GRIN3A HTT	9.03e-06	2	105	2	23852340
Pubmed	Expression of BMPRIA on human thymic NK cell precursors: role of BMP signaling in intrathymic NK cell development.	BMP4 BMPR1A	9.03e-06	2	105	2	22210872
Pubmed	XY follicle cells in ovaries of XX----XY female mouse chimaeras.	BMP4 BMPR1A	9.03e-06	2	105	2	3268409
Pubmed	BMP4/ALK3 deficiency leads to Meckel's cartilage truncation mimicking the mandible Tessier 30 cleft.	BMP4 BMPR1A	9.03e-06	2	105	2	33759298
Pubmed	Genetic evidence of serum phosphate-independent functions of FGF-23 on bone.	FGF23 SLC34A1	9.03e-06	2	105	2	18688277
Pubmed	Regulation and function of bone morphogenetic protein signaling in colonic injury and inflammation.	BMP4 BMPR1A	9.03e-06	2	105	2	27856416
Pubmed	Identification of the ligand-binding site of the BMP type IA receptor for BMP-4.	BMP4 BMPR1A	9.03e-06	2	105	2	11241215
Pubmed	Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons.	OR2T35 OR2T2 OR2T11 OR6P1	1.16e-05	46	105	4	32126975
Pubmed	Quantitative trait loci for body size components in mice.	ADGRV1 FZD9 BMP4 BMPR1A FZD10	1.24e-05	98	105	5	16783635
Pubmed	Phosphaturic action of fibroblast growth factor 23 in Npt2 null mice.	FGF23 SLC34A1	2.70e-05	3	105	2	20357029
Pubmed	Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.	BMP4 BMPR1A	2.70e-05	3	105	2	15673568
Pubmed	Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart.	BMP4 BMPR1A	2.70e-05	3	105	2	24398041
Pubmed	CGG-repeat expansion in the DIP2B gene is associated with the fragile site FRA12A on chromosome 12q13.1.	DIP2B DIP2C	2.70e-05	3	105	2	17236128
Pubmed	Genetic variants associated with deep vein thrombosis: the F11 locus.	CYP4V2 KLKB1	2.70e-05	3	105	2	19583818
Pubmed	Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport.	FGF23 SLC34A1	2.70e-05	3	105	2	27432882
Pubmed	A new signaling cascade linking BMP4, BMPR1A, ΔNp73 and NANOG impacts on stem-like human cell properties and patient outcome.	BMP4 BMPR1A	2.70e-05	3	105	2	30262802
Pubmed	Direct BMP2/4 signaling through BMP receptor IA regulates fetal thymocyte progenitor homeostasis and differentiation to CD4+CD8+ double-positive cell.	BMP4 BMPR1A	2.70e-05	3	105	2	24240189
Pubmed	Involvement of Wnt, Eda and Shh at defined stages of sweat gland development.	BMP4 BMPR1A FZD10	3.95e-05	22	105	3	25249463
Pubmed	Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells.	BMP4 BMPR1A	5.40e-05	4	105	2	21152263
Pubmed	Gene expression analysis of kidneys from transgenic mice expressing fibroblast growth factor-23.	FGF23 SLC34A1	5.40e-05	4	105	2	17911089
Pubmed	Common genetic variants of the BMP4, BMPR1A, BMPR1B, and ACVR1 genes, left ventricular mass, and other parameters of the heart in newborns.	BMP4 BMPR1A	5.40e-05	4	105	2	22971142
Pubmed	Immunoexpression of BMP-2 and BMP-4 and their receptors, BMPR-IA and BMPR-II, in ameloblastomas and adenomatoid odontogenic tumors.	BMP4 BMPR1A	5.40e-05	4	105	2	27780042
Pubmed	Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction.	BMP4 BMPR1A	5.40e-05	4	105	2	11282024
Pubmed	Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-null animals.	FGF23 SLC34A1	5.40e-05	4	105	2	17148678
Pubmed	Tmem174, a regulator of phosphate transporter prevents hyperphosphatemia.	FGF23 SLC34A1	5.40e-05	4	105	2	35428804
Pubmed	Selective pharmacological inhibition of the sodium-dependent phosphate cotransporter NPT2a promotes phosphate excretion.	FGF23 SLC34A1	5.40e-05	4	105	2	32853180
Pubmed	BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling.	BMP4 BMPR1A	5.40e-05	4	105	2	15378062
Pubmed	Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch.	MRGPRD MRGPRX4	8.97e-05	5	105	2	17618277
Pubmed	FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice.	FAM209A FAM209B	8.97e-05	5	105	2	34471926
Pubmed	Cloning and characterization of a human type II receptor for bone morphogenetic proteins.	BMP4 BMPR1A	8.97e-05	5	105	2	7644468
Pubmed	BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies.	BMP4 BMPR1A	8.97e-05	5	105	2	12141440
Pubmed	Genetic elucidation of human hyperosmia to isovaleric acid.	OR11H7 OR4E1	8.97e-05	5	105	2	17973576
Pubmed	Expression of bone morphogenetic proteins 4 and 7 and their receptors IA, IB, and II in human ovaries from fetuses and adults.	BMP4 BMPR1A	8.97e-05	5	105	2	17624341
Pubmed	In vivo evidence for an interplay of FGF23/Klotho/PTH axis on the phosphate handling in renal proximal tubules.	FGF23 SLC34A1	1.34e-04	6	105	2	29993278
Pubmed	Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.	BMP4 BMPR1A	1.34e-04	6	105	2	16604073
Pubmed	Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.	BMP4 BMPR1A	1.34e-04	6	105	2	8006002
Pubmed	Disruption in CYLC1 leads to acrosome detachment, sperm head deformity, and male in/subfertility in humans and mice.	FAM209A FAM209B	1.34e-04	6	105	2	38573307
Pubmed	Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate.	BMP4 BMPR1A	1.34e-04	6	105	2	11401393
Pubmed	Visualizing the Itch-Sensing Skin Arbors.	MRGPRD MRGPRX4	1.34e-04	6	105	2	33091423
Pubmed	Genetic identification of C fibres that detect massage-like stroking of hairy skin in vivo.	MRGPRD MRGPRX4	1.34e-04	6	105	2	23364746
Pubmed	BMP signaling plays a role in visceral endoderm differentiation and cavitation in the early mouse embryo.	BMP4 BMPR1A	1.34e-04	6	105	2	9876182
Pubmed	FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1.	FGF23 SLC34A1	1.34e-04	6	105	2	19515808
Pubmed	Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.	MRGPRD MRGPRX4	1.34e-04	6	105	2	24549959
Pubmed	MrgprC11+ sensory neurons mediate glabrous skin itch.	MRGPRD MRGPRX4	1.34e-04	6	105	2	33876765
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIP2B TM9SF4 UBR4 KCND2	1.44e-04	87	105	4	12465718
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR2T11 OR6P1 OR4X1	1.63e-04	35	105	3	16939646
Pubmed	The DNA sequence and comparative analysis of human chromosome 20.	TRPC4AP FAM209A RBL1 TM9SF4 SLC2A10 XKR7 DEFB132 FAM209B	1.79e-04	517	105	8	11780052
Pubmed	Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity.	MRGPRD MRGPRX4	1.88e-04	7	105	2	36693373
Pubmed	Differential effects of BMP signaling on parvalbumin and somatostatin interneuron differentiation.	BMP4 BMPR1A	1.88e-04	7	105	2	19592576
Pubmed	BMP and BMP receptor expression during murine organogenesis.	BMP4 BMPR1A	1.88e-04	7	105	2	19393343
Pubmed	Synteny of orthologous genes conserved in mammals, snake, fly, nematode, and fission yeast.	UNC93A MPC1	1.88e-04	7	105	2	11252172
Pubmed	Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon.	FZD9 FZD10	1.88e-04	7	105	2	11335128
Pubmed	Differential expression of BMP receptors in early mouse development.	BMP4 BMPR1A	1.88e-04	7	105	2	9303341
Pubmed	Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter.	BMP4 BMPR1A	1.88e-04	7	105	2	10749566
Pubmed	DRAGON, a bone morphogenetic protein co-receptor.	BMP4 BMPR1A	2.50e-04	8	105	2	15671031
Pubmed	HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis.	BMP4 BMPR1A	2.50e-04	8	105	2	15342482
Pubmed	BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.	BMP4 BMPR1A	2.50e-04	8	105	2	17301089
Pubmed	Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5.	BMP4 BMPR1A	2.50e-04	8	105	2	8702914
Pubmed	Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation.	BMP4 BMPR1A	2.50e-04	8	105	2	20043884
Pubmed	Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600.	RBL1 UBR4	2.50e-04	8	105	2	16061792
Pubmed	Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes.	MRGPRD MRGPRX4	2.50e-04	8	105	2	24583173
Pubmed	Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.	MRGPRD MRGPRX4	2.50e-04	8	105	2	12909716
Pubmed	An atlas of genetic influences on human blood metabolites.	ANKH SCAPER DIP2C SLC7A5 KLKB1	2.86e-04	190	105	5	24816252
Pubmed	WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.	BMP4 BMPR1A	3.21e-04	9	105	2	21054789
Pubmed	DIP2 disco-interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin-related protein/follistatin-like 1--analysis of their binding with TGF-β superfamily proteins.	BMP4 BMPR1A	3.21e-04	9	105	2	20860622
Pubmed	An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth.	BMP4 BMPR1A	3.21e-04	9	105	2	18594511
Pubmed	Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.	MRGPRD MRGPRX4	3.21e-04	9	105	2	12397184
Pubmed	Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes.	BMP4 BMPR1A	3.21e-04	9	105	2	9389648
Pubmed	A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.	FZD9 FZD10	3.21e-04	9	105	2	9707618
Pubmed	Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis.	BMP4 BMPR1A	3.21e-04	9	105	2	8674409
Pubmed	The role of the histone methyltransferase SET domain bifurcated 1 during palatal development.	BMP4 BMPR1A	4.00e-04	10	105	2	35151207
Pubmed	Expression of Frizzled genes in developing and postnatal hair follicles.	FZD9 FZD10	4.00e-04	10	105	2	15245425
Pubmed	Exposure of phosphatidylserine by Xk-related protein family members during apoptosis.	XKR9 XKR7	4.00e-04	10	105	2	25231987
Pubmed	Negative and positive auto-regulation of BMP expression in early eye development.	BMP4 BMPR1A	4.00e-04	10	105	2	26407529
Pubmed	Bone morphogenetic protein 6-induced interleukin-1β expression in macrophages requires PU.1/Smad1 interaction.	BMP4 BMPR1A	4.00e-04	10	105	2	21571370
Pubmed	BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells.	BMP4 BMPR1A	4.00e-04	10	105	2	18436533
Pubmed	A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.	ADGRV1 PGAP1	4.00e-04	10	105	2	17329413
Pubmed	BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo.	BMP4 BMPR1A	4.88e-04	11	105	2	15289457
Pubmed	BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling.	BMP4 BMPR1A	4.88e-04	11	105	2	17537800
Pubmed	Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.	FZD9 FZD10	4.88e-04	11	105	2	24860427
Pubmed	A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.	MRGPRD MRGPRX4	4.88e-04	11	105	2	11551509
Pubmed	BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo.	BMP4 BMPR1A	4.88e-04	11	105	2	20406889
Pubmed	Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.	FZD9 FZD10	4.88e-04	11	105	2	17582687
Pubmed	Distinct functions for Bmp signaling in lip and palate fusion in mice.	BMP4 BMPR1A	4.88e-04	11	105	2	15716346
Pubmed	Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.	FZD9 FZD10	4.88e-04	11	105	2	17576136
Pubmed	Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT.	BMP4 BMPR1A	4.88e-04	11	105	2	18233958
Pubmed	Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice.	BMP4 BMPR1A	5.84e-04	12	105	2	23891934
Pubmed	The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.	BMP4 BMPR1A	5.84e-04	12	105	2	19812316
Pubmed	Venous identity requires BMP signalling through ALK3.	BMP4 BMPR1A	5.84e-04	12	105	2	30692543
Pubmed	BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb.	BMP4 BMPR1A	5.84e-04	12	105	2	11714671
Pubmed	BMPs are direct triggers of interdigital programmed cell death.	BMP4 BMPR1A	5.84e-04	12	105	2	26826495
Interaction	SYNGR1 interactions	FAM209A UNC93A TMBIM6 CMTM5 ALG3 TMCO1 HTT	3.58e-07	109	84	7	int:SYNGR1
Interaction	SLC1A1 interactions	FAM209A TM9SF4 TMBIM6 CHPT1 GOLGA7 KDELR1 TMCO1	9.18e-06	177	84	7	int:SLC1A1
Interaction	CLDND1 interactions	BMPR1A GOLGA7 ALG3 TMCO1 QSOX2	1.09e-05	70	84	5	int:CLDND1
Cytoband	1q44	OR2M2 OR2T35 OR2T2 OR2T4 OR2T11 OR6F1 OR2T6	6.55e-09	110	104	7	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2M2 OR2T35 OR2T2 OR2T4 OR2T11 OR6F1 OR2T6	1.88e-08	128	104	7	chr1q44
Cytoband	20q13.31	FAM209A FAM209B	5.97e-04	16	104	2	20q13.31
Cytoband	3q12.1	OR5K4 OR5K3	1.04e-03	21	104	2	3q12.1
GeneFamily	Olfactory receptors, family 2	OR2M2 OR2T35 OR2T2 OR2T4 OR2T11 OR2T6 OR2AT4 OR2Z1	2.95e-08	113	78	8	149
GeneFamily	Olfactory receptors, family 6	OR6C65 OR6P1 OR6F1 OR6B3 OR6B2	2.64e-06	51	78	5	153
GeneFamily	Blood group antigens\|XK related family	XKR9 XKR7	9.85e-04	11	78	2	955
GeneFamily	G protein-coupled receptors, Class F frizzled	FZD9 FZD10	9.85e-04	11	78	2	286
GeneFamily	Olfactory receptors, family 10	OR10J3 OR10G6 OR10W1	2.91e-03	66	78	3	157
GeneFamily	G protein-coupled receptors, Class A orphans	MRGPRD GPR52 MRGPRX4	4.66e-03	78	78	3	262
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	FZD9 BMPR1A CD36 FZD10 CD72 SLC7A5	7.09e-03	394	78	6	471
GeneFamily	Solute carriers	SLC2A10 SLC13A4 SLC34A1 SLC15A4 SLC7A5 SLC14A2	7.17e-03	395	78	6	752
Disease	esophagitis (is_marker_for)	BMP4 SLC7A5	9.41e-06	2	91	2	DOID:11963 (is_marker_for)
Disease	plasma kallikrein measurement	CYP4V2 KLKB1	1.40e-04	6	91	2	EFO_0008260
Disease	plasma serine protease inhibitor measurement	CYP4V2 KLKB1	1.40e-04	6	91	2	EFO_0020642
Disease	neuropeptide W measurement	CYP4V2 KLKB1	1.40e-04	6	91	2	EFO_0801835
Disease	rho GTPase-activating protein 30 measurement	CYP4V2 KLKB1	1.96e-04	7	91	2	EFO_0802012
Disease	thrombin measurement	CYP4V2 KLKB1	2.60e-04	8	91	2	EFO_0020768
Disease	factor XI measurement	CYP4V2 KLKB1	2.60e-04	8	91	2	EFO_0004694
Disease	Odontome	ANKH TMCO1	4.17e-04	10	91	2	C0524730
Disease	Tooth Abnormalities	ANKH TMCO1	4.17e-04	10	91	2	C0040427
Disease	persulfide dioxygenase ETHE1, mitochondrial measurement	CYP4V2 KLKB1	6.08e-04	12	91	2	EFO_0008258
Disease	transmembrane protein 87B measurement	CYP4V2 KLKB1	7.18e-04	13	91	2	EFO_0802158
Disease	juvenile polyposis syndrome (implicated_via_orthology)	BMP4 BMPR1A	7.18e-04	13	91	2	DOID:0050787 (implicated_via_orthology)
Disease	androgenetic alopecia	DIP2B FAF1 KCND2 SLC14A2	7.79e-04	133	91	4	EFO_0004191
Disease	sulfate measurement	SLC34A1 HTT	8.36e-04	14	91	2	EFO_0007864
Disease	phosphorus measurement	FGF23 SLC34A1	1.10e-03	16	91	2	EFO_0004861
Disease	vitamin C measurement	CHPT1 SLC34A1	1.10e-03	16	91	2	EFO_0600003
Disease	cytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant	FAM209A FAM209B	1.55e-03	19	91	2	EFO_0007044, EFO_0020106
Disease	prostate carcinoma (is_marker_for)	TMBIM6 BMP4	2.28e-03	23	91	2	DOID:10286 (is_marker_for)
Disease	Fanconi Anemia	XRCC2 RFWD3	2.69e-03	25	91	2	C0015625

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLCLTCSYAFMFSSL	FAM209A	11	Q5JX71
LDAIAKTCTFTAMCF	AADACL2	36	Q6P093
FMCCASYRVHSIFVL	ALG3	156	Q92685
CRCNYTSVVMSFSIL	ADGRF4	376	Q8IZF3
CLAVLSHIFCARYSM	ADGRV1	5921	Q8WXG9
SCRSSLPYICEMTAF	CD72	341	P21854
ACCVPTELSAISMLY	BMP4	371	P12644
MHTLAASLSACIYQC	DMXL1	2231	Q9Y485
LFMCNASRKCCISYS	DEFB132	46	Q7Z7B7
ACLTAYTIFLCMETH	GOLGA7	71	Q7Z5G4
ISGRMTFALCCYSLT	MPC1	51	Q9Y5U8
CMKDTYLVHLTCSSS	CHML	501	P26374
FSSLDMSLCVVLYVA	QSOX2	656	Q6ZRP7
RIMAYCDALSCLVIS	RFWD3	451	Q6PCD5
VSVSYGSCIFMCVKT	OR6C65	246	A6NJZ3
ICAGTECFLLAVMAY	OR9I1	106	Q8NGQ6
AYSALSCCFISEDLM	RELCH	1116	Q9P260
HTETCLCTSMYYFLG	OR10W1	41	Q8NGF6
TDTSLYETLMYACCV	OR2T2	191	Q6IF00
AISLSSMACCIYVSE	SLC2A10	111	O95528
GLFAVLLSCCASAMY	KCNK12	221	Q9HB15
LLSCCASAMYTSVEG	KCNK12	226	Q9HB15
SLSGSECFLLAVMAY	OR2M2	106	Q96R28
CSDTSLYEIFMYLCC	OR2T4	221	Q8NH00
TISFIACTAQCFLYM	OR2T6	91	Q8NHC8
KLSCADTCAYEMALS	OR2Z1	186	Q8NG97
LSYLSFVEICYCSVM	OR4X1	61	Q8NH49
LLCLTCSYAFMFSSL	FAM209B	11	Q5JX69
CNIYTSLDVMLCTAS	HRH2	91	P25021
RDTFCSYSVMELCTK	DIP2B	1246	Q9P265
AYLVLSSLAMFTCLC	MRGPRD	26	Q8TDS7
CLDTACVMIFTVEYL	KCND2	231	Q9NZV8
SLVFTCVMTLLYAFS	SLC7A5	376	Q01650
LAETTDCFLLAAMAY	OR5K3	106	A6NET4
DTSLYETLMYACCVL	OR2T35	191	Q8NGX2
FDICCISVSYTMILQ	OR52N2	211	Q8NGI0
SVSMACLACISVDRY	GPR52	126	Q9Y2T5
IFCMFCLSTYTANLA	GRIN3A	751	Q8TCU5
FLCILASYMHITCTV	OR1F1	211	O43749
LYLFVCSLDMLSSAF	SLC34A1	111	Q06495
SMLLCSLSEAICFFL	NPC1L1	746	Q9UHC9
ALACTECVLLAVMAY	OR6P1	106	Q8NGX9
FLCSLYAPMCTEQVS	FZD10	86	Q9ULW2
FLCSLYAPMCTDQVS	FZD9	91	O00144
ATMILSTILCCIAFF	EMP2	66	P54851
RNCVMSLCSSSYSEL	HTT	831	P42858
FVAFMISYCACRSKT	CD36	456	P16671
CALCSVCSMSVLRAY	FGF23	11	Q9GZV9
AVCIIAMIIFSSCFC	BMPR1A	161	P36894
VRDTFCSYSVMELCT	DIP2C	1226	Q9Y2E4
KFTFVCMALSLTLCF	ANKH	326	Q9HCJ1
YITLCALDIICETAM	CYP4V2	191	Q6ZWL3
TAMIFTCFTLSALYA	TMBIM6	121	P55061
CFDFSTLLCSMLIGS	DRC7	186	Q8IY82
TCTKMIRCQFFTYSL	KLKB1	321	P03952
CTRTYVIAASTMSVC	KRTAP10-8	6	P60410
CSQMLCAESIVSYLS	FAF1	391	Q9UNN5
MSSVYLQCKVLICDS	CUZD1	491	Q86UP6
TCMKVVYIACSFTTV	KDELR1	61	P24390
DQMICKCLSLSISYS	SLC13A4	261	Q9UKG4
CSVGRLLIFFMCSSS	SDIM1	6	Q6ZPB5
AFTDMFKILTYSCCS	SLC15A4	256	Q8N697
MCTLCFAVTGRSYSI	SCAPER	1146	Q9BY12
MFVLLYVTSFAICAS	C1QTNF7	1	Q9BXJ2
CMAGVSRSASLCLAY	DUSP21	106	Q9H596
LFMCTLSLSVTYLCY	HS3ST4	36	Q9Y661
GCMTQLYFFSSLVCT	OR6B2	96	Q6IFH4
SLVCTECVLLASMAY	OR6B2	106	Q6IFH4
SLGTTECFFLCVMAY	OR11H7	106	Q8NGC8
SCLLQMYLFQSFTCS	OR2AT4	101	A6NND4
SFTCSEAFILVVMAY	OR2AT4	111	A6NND4
HFLGCTECFLYTLMA	OR10G6	126	Q8NH81
CADTSLYETLMYICC	OR2T11	186	Q8NH01
TYCDHMSVVKLSCAS	OR52N5	186	Q8NH56
SCLLQMYFVFSLGCT	OR6F1	96	Q8NGZ6
YFFLCMLSISETCYT	OR10J3	61	Q5JRS4
KTMALCFVIFSFCSL	SVOP	401	Q8N4V2
EMSKDCLSILYNTCV	TRPC4AP	161	Q8TEL6
DCSFIFLYILCTMSI	TMCO1	191	Q9UM00
LTMAATFDDCLYALC	GFOD1	331	Q9NXC2
LMACCLEIVLFAYSS	RBL1	501	P28749
MTGIFCTISLCTYAA	TMEM178A	216	Q8NBL3
SLFSTGCCLEYATML	PGAP1	616	Q75T13
CHVYLVCMSLSSLNS	MRGPRX4	251	Q96LA9
GCMTQLYFFSSLVCT	OR6B3	96	Q8NGW1
SLVCTECVLLASMAY	OR6B3	106	Q8NGW1
LAETTDCFLLATMAY	OR5K4	106	A6NMS3
MSQKLRVELTSCCYF	OR5L2	136	Q8NGL0
CFTASISAYMAAALL	CMTM5	51	Q96DZ9
VISSFDMVIYFSALC	CHPT1	356	Q8WUD6
EYSIHSLFCIMFLCA	CNIH3	71	Q8TBE1
LCSLICYRSSMTAEQ	STK31	951	Q9BXU1
CLVCEMSSLFRELYS	USP27X	121	A6NNY8
DFYSLIMVCVVASSF	XKR7	411	Q5GH72
SLLLFSLMCETSAFY	TM9SF4	11	Q92544
FACTEIFLLTVMAYD	OR4E1	111	P0C645
IFCIASAMSLYNCLA	SPPL2A	251	Q8TCT8
MICFSATDALCSVLY	UNC93A	296	Q86WB7
TACMCVYGLLSFVLT	NUP188	376	Q5SRE5
YDILVACSSSCPVMF	TAAR2	191	Q9P1P5
YSLESMFCSHPSLCL	XRCC2	131	O43543
CSICLDYFTDPVMTT	TRIM17	16	Q9Y577
YTELLTCYALMFSFC	ZDHHC21	141	Q8IVQ6
CSLSFYALSNTAMEL	ZACN	171	Q401N2
CLYAGVSVATCMAIL	UBR4	336	Q5T4S7
LALICALFCAYMEAA	SLC14A2	371	Q15849
TQFCTCISMEFLYRI	XKR9	251	Q5GH70
SMRTYVCHICSIAFT	ZMAT1	171	Q5H9K5
VLSGEVYTCMCFLID	VPS13D	2276	Q5THJ4