Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

GLUD1 GLUD2

3.40e-0521172GO:0016639
GeneOntologyMolecularFunctionglutamate dehydrogenase [NAD(P)+] activity

GLUD1 GLUD2

3.40e-0521172GO:0004353
GeneOntologyMolecularFunctionglutamate dehydrogenase (NAD+) activity

GLUD1 GLUD2

3.40e-0521172GO:0004352
GeneOntologyMolecularFunctionglutamate dehydrogenase (NADP+) activity

GLUD1 GLUD2

3.40e-0521172GO:0004354
GeneOntologyMolecularFunctionstructural constituent of nuclear pore

NUP107 NUP205 NUP133

4.10e-04251173GO:0017056
GeneOntologyMolecularFunctionL-leucine binding

GLUD1 GLUD2

7.01e-0471172GO:0070728
MousePhenoabnormal body length

DYM STARD4 SPTAN1 KDM3B CHD2 GRIK3 ZFC3H1 MREG PPP2R2A NUP133 GREB1 BCAR3 GNL1 CSGALNACT1 DEUP1

2.76e-065509215MP:0001256
MousePhenodecreased body length

DYM STARD4 SPTAN1 KDM3B CHD2 GRIK3 MREG PPP2R2A NUP133 GREB1 BCAR3 GNL1 CSGALNACT1 DEUP1

3.12e-064849214MP:0001258
DomainELFV_dehydrog_N

GLUD1 GLUD2

3.82e-0521162PF02812
DomainUncharacterised_TMEM39

TMEM39B TMEM39A

3.82e-0521162IPR019397
DomainGlu/Leu/Phe/Val_DH_C

GLUD1 GLUD2

3.82e-0521162IPR006096
DomainGlu/Leu/Phe/Val_DH_dimer_dom

GLUD1 GLUD2

3.82e-0521162IPR006097
DomainGlu/Leu/Phe/Val_DH

GLUD1 GLUD2

3.82e-0521162IPR006095
DomainTmp39

TMEM39B TMEM39A

3.82e-0521162PF10271
DomainELFV_dehydrog

GLUD1 GLUD2

3.82e-0521162PF00208
DomainNAD_bind_Glu_DH

GLUD1 GLUD2

3.82e-0521162IPR033922
DomainGLFV_DEHYDROGENASE

GLUD1 GLUD2

3.82e-0521162PS00074
DomainELFV_dehydrog

GLUD1 GLUD2

3.82e-0521162SM00839
DomainGlu/Leu/Phe/Val_DH_AS

GLUD1 GLUD2

3.82e-0521162IPR033524
Domain-

PLXNA3 FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A NUP133 PLXNA1

4.35e-05333116102.130.10.10
DomainWD40/YVTN_repeat-like_dom

PLXNA3 FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A NUP133 PLXNA1

4.58e-0533511610IPR015943
DomainPP2A_PR55_CS

PPP2R2D PPP2R2A

2.28e-0441162IPR018067
DomainPP2A_PR55

PPP2R2D PPP2R2A

2.28e-0441162IPR000009
DomainPR55_2

PPP2R2D PPP2R2A

2.28e-0441162PS01025
DomainPR55_1

PPP2R2D PPP2R2A

2.28e-0441162PS01024
DomainIPT

PLXNA3 PKHD1L1 PLXNA1

6.12e-04271163SM00429
DomainTIG

PLXNA3 PKHD1L1 PLXNA1

9.24e-04311163PF01833
DomainIPT

PLXNA3 PKHD1L1 PLXNA1

1.02e-03321163IPR002909
DomainPlexin_cytopl

PLXNA3 PLXNA1

1.34e-0391162PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA1

1.34e-0391162IPR013548
DomainPlexin

PLXNA3 PLXNA1

1.34e-0391162IPR031148
DomainWD_REPEATS_1

FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A

1.76e-032781167PS00678
DomainWD_REPEATS_2

FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A

1.80e-032791167PS50082
DomainWD_REPEATS_REGION

FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A

1.80e-032791167PS50294
Domain-

ABCA2 NWD1 DYNC2H1 ABCA13 RNF213 CHD2 AK3 DNAH1 ORC5 SAMD9L GNL1 NLRP4

2.33e-03746116123.40.50.300
DomainP-loop_NTPase

ABCA2 NWD1 KIF1A DYNC2H1 ABCA13 RNF213 CHD2 AK3 DNAH1 ORC5 SAMD9L GNL1 NLRP4

2.33e-0384811613IPR027417
DomainABC_A

ABCA2 ABCA13

2.42e-03121162IPR026082
DomainWD40_repeat_dom

FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A

2.55e-032971167IPR017986
DomainZF_RING_2

TRIM49D1 RNF213 ZSWIM2 ARIH2 UBR3 TRIM38 TRIM37

2.60e-032981167PS50089
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH1

3.31e-03141162IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH1

3.31e-03141162IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH1

3.31e-03141162IPR013602
DomainDHC_N2

DYNC2H1 DNAH1

3.31e-03141162PF08393
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH1

3.31e-03141162IPR011704
DomainMT

DYNC2H1 DNAH1

3.31e-03141162PF12777
DomainAAA_8

DYNC2H1 DNAH1

3.31e-03141162PF12780
DomainAAA_5

DYNC2H1 DNAH1

3.31e-03141162PF07728
DomainDHC_fam

DYNC2H1 DNAH1

3.81e-03151162IPR026983
DomainDynein_heavy

DYNC2H1 DNAH1

3.81e-03151162PF03028
DomainPI3/4_kinase_CS

PIK3CD ATM

3.81e-03151162IPR018936
DomainDynein_heavy_dom

DYNC2H1 DNAH1

3.81e-03151162IPR004273
DomainZnf_RING

TRIM49D1 RNF213 ZSWIM2 ARIH2 UBR3 TRIM38 TRIM37

4.26e-033261167IPR001841
Domain-

PIK3CD ATM

4.34e-031611621.10.1070.11
DomainPI3Kc

PIK3CD ATM

4.34e-03161162SM00146
Domain-

PLXNA3 RASA2

4.34e-031611621.10.506.10
DomainARM-type_fold

USP34 VEPH1 HEATR1 PIK3CD NOC4L ATM TARBP1

5.26e-033391167IPR016024
DomainPI3_PI4_kinase

PIK3CD ATM

5.48e-03181162PF00454
DomainPI3_4_KINASE_1

PIK3CD ATM

5.48e-03181162PS00915
DomainPI3_4_KINASE_2

PIK3CD ATM

5.48e-03181162PS00916
DomainPI3/4_kinase_cat_dom

PIK3CD ATM

5.48e-03181162IPR000403
DomainRasGAP_dom

PLXNA3 RASA2

5.48e-03181162IPR001936
DomainPI3_4_KINASE_3

PIK3CD ATM

5.48e-03181162PS50290
DomainWD40

FBXW10B FBXW10 NWD1 PPP2R2D WDR19 PPP2R2A

5.60e-032591166PF00400
DomainCARBOXYPEPT_ZN_2

CPD AGBL2

6.10e-03191162PS00133
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

GLUD1 GLUD2 GABPA

3.03e-0511823MM14866
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 NUP107 NCKAP1 KIF1A NPEPPS SPTAN1 NOL6 CHD2 HEATR1 URB2 NUP205 NUP133 NOC4L ATM

6.34e-086531201422586326
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

USP34 ABCA2 KIF1A SPTAN1 HECTD4 NCAPH2 ZFC3H1 ZKSCAN5 TERF2IP WDR19 FRY ARIH2 GLUD1 FMN2 ATM CABIN1 TARBP1 TRIM37 KLHL4

9.02e-0812851201935914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 ABCA2 ZSCAN12 PPP2R2D VPS13C HECTD4 KDM3B NUP205 WDR19 PPP2R2A ATP11B ESPL1

3.23e-075291201214621295
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 USP34 ABCA2 GOLM2 ERO1A LAMA4 RNF213 CPD NCAPH2 LRP8 THEM6 PPP2R2A UGGT2 ATM CSGALNACT1 PLXNA1 CDON

8.41e-0712011201735696571
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

NUP107 PPP2R2D DYNC2H1 NPEPPS NCAPH2 HEATR1 THEM6 ORC5 PPP2R2A GLUD1 GLUD2 NUP133

1.34e-066061201236538041
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 KIF1A PPP2R2D NPEPPS ERO1A CPD NCAPH2 HEATR1 NUP205 THEM6 PPP2R2A PTPN14 GLUD1 NUP133 ESPL1

1.41e-069741201528675297
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NUP107 NCKAP1 KIF1A DYNC2H1 NPEPPS VPS13C ERO1A SPTAN1 NOL6 HEATR1 URB2 NUP205 PPP2R2A GLUD1 NUP133 NOC4L ATM PLXNA1

1.96e-0614251201830948266
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

PDE8A NUP107 NCKAP1 PPP2R2D DYNC2H1 DCTN2 NCAPH2 HEATR1 NUP205 WDR19 THEM6 PPP2R2A SLC9C1 PTPN14 NUP133 UGGT2 COL14A1

3.04e-0613211201727173435
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NUP107 DYNC2H1 DCTN2 ERO1A SPTAN1 CPD HEATR1 ZFC3H1 WDR19 THEM6 PTPN14 GLUD1 NUP133 NOC4L UGGT2 COL14A1 ATM ESPL1

3.56e-0614871201833957083
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

PLXNA3 FBXW10B ZSCAN12 KIF1A ABCA13 KDM3B MUC16 RNF213 GRIK3 HEATR1 ATP11B

3.56e-065521201110737800
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DYM RASA2 KIF1A NPEPPS VPS13C GOLM2 HECTD4 RNF213 CHD2 CPD TERF2IP LRP8 DNAH1 PPP2R2A ATP11B GALNT11 GREB1 CSMD1

3.62e-0614891201828611215
Pubmed

Functional loss of semaphorin 3C and/or semaphorin 3D and their epistatic interaction with ret are critical to Hirschsprung disease liability.

PLXNA3 RET PLXNA1

8.61e-0612120325839327
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

CCDC14 DYNC2H1 ERO1A NOL6 LAMA4 NLGN1 HEATR1 NOC4L

1.07e-05302120830561431
Pubmed

Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.

GLUD1 GLUD2

1.18e-052120215750346
Pubmed

Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.

GLUD1 GLUD2

1.18e-05212021711373
Pubmed

Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.

GLUD1 GLUD2

1.18e-052120234173171
Pubmed

Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.

GLUD1 GLUD2

1.18e-052120228621566
Pubmed

Purification, crystallization and preliminary X-ray analysis of a Nup107-Nup133 heterodimeric nucleoporin complex.

NUP107 NUP133

1.18e-052120217768364
Pubmed

GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.

GLUD1 GLUD2

1.18e-052120232078638
Pubmed

Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.

GLUD1 GLUD2

1.18e-052120220529287
Pubmed

Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.

GLUD1 GLUD2

1.18e-052120223595828
Pubmed

Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).

GLUD1 GLUD2

1.18e-052120225124006
Pubmed

Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex.

NUP107 NUP133

1.18e-052120215557116
Pubmed

Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.

GLUD1 GLUD2

1.18e-052120223673664
Pubmed

Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.

GLUD1 GLUD2

1.18e-052120221621574
Pubmed

Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.

GLUD1 GLUD2

1.18e-052120239052831
Pubmed

Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.

GLUD1 GLUD2

1.18e-052120224442550
Pubmed

Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice.

USP34 ATM

1.18e-052120237043976
Pubmed

Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.

GLUD1 GLUD2

1.18e-052120228911206
Pubmed

Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization.

PGR GREB1

1.18e-052120228911214
Pubmed

Expression and alternative splicing of N-RAP during mouse skeletal muscle development.

NRAP NOL6

1.18e-052120218792955
Pubmed

The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.

GLUD1 GLUD2

1.18e-052120227137930
Pubmed

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.

GLUD1 GLUD2

1.18e-052120226440896
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

1.18e-052120231400758
Pubmed

Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.

GLUD1 GLUD2

1.18e-052120222875990
Pubmed

Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.

GLUD1 GLUD2

1.18e-052120212742085
Pubmed

Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.

GLUD1 GLUD2

1.18e-052120215578726
Pubmed

Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.

GLUD1 GLUD2

1.18e-052120215044002
Pubmed

Induction of excitatory and inhibitory presynaptic differentiation by GluD1.

GLUD1 GLUD2

1.18e-052120222138648
Pubmed

Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.

GLUD1 GLUD2

1.18e-052120234220417
Pubmed

ERO1L promotes IL6/sIL6R signaling and regulates MUC16 expression to promote CA125 secretion and the metastasis of lung cancer cells.

ERO1A MUC16

1.18e-052120233056994
Pubmed

Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.

GLUD1 GLUD2

1.18e-052120226241911
Pubmed

Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element.

NUP107 NUP133

1.18e-052120219674973
Pubmed

Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex.

NUP107 NUP133

1.18e-052120218570875
Pubmed

Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.

GLUD1 GLUD2

1.18e-052120221446915
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

1.18e-052120237450367
Pubmed

Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.

GLUD1 GLUD2

1.18e-052120218688271
Pubmed

The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.

GLUD1 GLUD2

1.18e-052120222658952
Pubmed

GluD1 binds GABA and controls inhibitory plasticity.

GLUD1 GLUD2

1.18e-052120238060673
Pubmed

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling.

PPP2R2D PPP2R2A

1.18e-052120218697906
Pubmed

Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.

GLUD1 GLUD2

1.18e-052120224593767
Pubmed

Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.

GLUD1 GLUD2

1.18e-052120238124277
Pubmed

Potentiation of neuronal activity by tonic GluD1 current in brain slices.

GLUD1 GLUD2

1.18e-052120237154294
Pubmed

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

GLUD1 GLUD2

1.18e-052120219015267
Pubmed

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.

GLUD1 GLUD2

1.18e-052120222924626
Pubmed

Biallelic Mutations in Nuclear Pore Complex Subunit NUP107 Cause Early-Childhood-Onset Steroid-Resistant Nephrotic Syndrome.

NUP107 NUP133

1.18e-052120226411495
Pubmed

Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.

GLUD1 GLUD2

1.18e-052120219448744
Pubmed

The conserved Nup107-160 complex is critical for nuclear pore complex assembly.

NUP107 NUP133

1.18e-052120212705868
Pubmed

Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.

GLUD1 GLUD2

1.18e-052120211032875
Pubmed

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.

GLUD1 GLUD2

1.18e-052120211950837
Pubmed

Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.

GLUD1 GLUD2

1.18e-052120229943084
Pubmed

The conserved transmembrane protein TMEM-39 coordinates with COPII to promote collagen secretion and regulate ER stress response.

TMEM39B TMEM39A

1.18e-052120233524011
Pubmed

Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.

GLUD1 GLUD2

1.18e-052120231898404
Pubmed

Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.

GLUD1 GLUD2

1.18e-052120215378063
Pubmed

Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.

GLUD1 GLUD2

1.18e-052120227422263
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC14 NUP107 PPP2R2D GOLM2 SPTAN1 RNF213 CPD PPP2R2A PTPN14 SSH3 NUP133 FMN2 UBR3 NOC4L

1.63e-0510491201427880917
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

USP34 ZSCAN12 NUP107 NCKAP1 GOLM2 NOL6 CHD2 CPD HEATR1 URB2 ZFC3H1 NUP205 THEM6 ORC5 NOC4L

1.77e-0512031201529180619
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

NUP107 NOL6 RNF213 HEATR1 URB2 NUP205 NUP133 NOC4L

2.11e-05332120825693804
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DYNC2H1 DCTN2 DNAH1 FUT4

2.14e-054712048812413
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NUP107 NCKAP1 KIF1A DYNC2H1 CPD HEATR1 URB2 NUP205 THEM6 NUP133 UGGT2 ESPL1 TARBP1

2.36e-059421201331073040
Pubmed

Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.

GLUD1 GLUD2

3.53e-053120229784783
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1

3.53e-05312028806646
Pubmed

The structure of apo human glutamate dehydrogenase details subunit communication and allostery.

GLUD1 GLUD2

3.53e-053120212054821
Pubmed

Predicting Lymph Node Metastasis in Endometrial Cancer Using Serum CA125 Combined with Immunohistochemical Markers PR and Ki67, and a Comparison with Other Prediction Models.

MUC16 PGR

3.53e-053120227163153
Pubmed

Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.

GLUD1 GLUD2

3.53e-053120231704028
Pubmed

Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase.

GLUD1 GLUD2

3.53e-053120229229616
Pubmed

Liver Glutamate Dehydrogenase Controls Whole-Body Energy Partitioning Through Amino Acid-Derived Gluconeogenesis and Ammonia Homeostasis.

GLUD1 GLUD2

3.53e-053120230002133
Pubmed

Cytoplasmic dynein promotes HIV-1 uncoating.

DYNC2H1 DCTN2

3.53e-053120225375884
Pubmed

Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens.

GLUD1 GLUD2

3.53e-053120230315226
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1

3.53e-053120211241833
Pubmed

Isolation of a human brain cDNA for glutamate dehydrogenase.

GLUD1 GLUD2

3.53e-05312023585334
Pubmed

GOT1 regulates CD8+ effector and memory T cell generation.

GLUD1 GLUD2

3.53e-053120236640309
Pubmed

Screening for new inhibitors of the human Mitochondrial Pyruvate Carrier and their effects on hepatic glucose production and diabetes.

GLUD1 GLUD2

3.53e-053120237871770
Pubmed

Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning.

GLUD1 GLUD2

3.53e-053120223560106
Pubmed

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.

GLUD1 GLUD2

3.53e-053120220670938
Pubmed

Comprehensive immunohistochemical analysis of RET, BCAR1, and BCAR3 expression in patients with Luminal A and B breast cancer subtypes.

RET BCAR3

3.53e-053120235031902
Pubmed

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PLXNA3 PLXNA1

3.53e-053120220138877
Pubmed

Identification of disulfide bond formation between MitoNEET and glutamate dehydrogenase 1.

GLUD1 GLUD2

3.53e-053120224295216
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 DYM DCTN2 NPEPPS ERO1A SPTAN1 NOL6 RNF213 HEATR1 NUP205 THEM6 PPP2R2A NUP133 NOC4L ATM CABIN1

3.69e-0514401201630833792
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ABHD17A PDE8A VPS13C URB2 PLEKHN1 LRP8 THEM6 ATP11B TMEM39A TARBP1 CSGALNACT1

4.12e-057191201135337019
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PLXNA3 FBXW10B FBXW10 KDM3B CPD GCNT7 GALNT11 SSH3 ARIH2 FUT4 PLXNA1

4.73e-057301201134857952
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

NUP107 DCTN2 NUP205 PPP2R2A NOC4L

5.76e-05118120537105989
Pubmed

Enriched expression of GluD1 in higher brain regions and its involvement in parallel fiber-interneuron synapse formation in the cerebellum.

GLUD1 GLUD2

7.05e-054120224872547
Pubmed

An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells.

NUP107 NUP133

7.05e-054120211564755
Pubmed

Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity.

GLUD1 GLUD2

7.05e-054120225721396
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA1

7.05e-054120211306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA1

7.05e-054120225518740
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

DYNC2H1 RNF213

7.05e-054120226147384
Pubmed

The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.

GLUD1 GLUD2

7.05e-054120223663782
Pubmed

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome.

NUP107 NUP133

7.05e-054120230179222
InteractionGPR182 interactions

ABCA2 DYM NCKAP1 RNF213 TMEM39B HEATR1 URB2 NUP205 THEM6 ATM FASTKD3 TARBP1 SEC14L1

2.22e-0645511613int:GPR182
InteractionOPALIN interactions

DYM RNF213 TMEM39B HEATR1 URB2 PLEKHN1 NUP205 ATM TARBP1

3.41e-062091169int:OPALIN
InteractionCD70 interactions

DYM NUP107 HEATR1 NUP205 ORC5 NUP133 ATM SEC14L1

5.35e-061661168int:CD70
Cytoband11q22-q23

PGR ATM

1.01e-046120211q22-q23
GeneFamilyWD repeat domain containing

FBXW10B FBXW10 NWD1 PPP2R2D WDR19 WDR93 PPP2R2A

1.60e-04262807362
GeneFamilyNucleoporins

NUP107 NUP205 NUP133

3.77e-04328031051
GeneFamilyPlexins

PLXNA3 PLXNA1

6.82e-049802683
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

1.04e-0311802559
GeneFamilyATP binding cassette subfamily A

ABCA2 ABCA13

1.70e-0314802805
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R2D PPP2R2A

1.96e-0315802696
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

DYM NUP107 SPTAN1 NOL6 RNF213 HEATR1 URB2 RET NUP205 MREG PIK3CD NUP133 ATM CABIN1 ESPL1 NLRP4 TCFL5 TRIM37

5.28e-0781011818gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

CCDC14 DYM NUP107 ERO1A NOL6 HEATR1 URB2 NUP205 MREG ATP11B NUP133 ATM FASTKD3 ESPL1 NLRP4 TRIM37

8.45e-0679511816gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE8A ABCA13 NPEPPS ERO1A ITIH5 MREG SAMD9L

7.24e-07187119714c239af77116d28d511dea754b6150d20488080
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA4 NLGN1 PGR PIEZO2 COL14A1 CSGALNACT1 KLHL4

9.27e-0719411975f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCKAP1 ABCA13 MUC16 CPD COL14A1 CSMD1 CDON

9.59e-071951197d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCKAP1 ABCA13 MUC16 CPD COL14A1 CSMD1 CDON

9.59e-07195119719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 VPS13C RNF213 CHD2 ZFC3H1 SAMD9L ATM

1.14e-06200119712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NWD1 DYNC2H1 ABCA13 MUC16 WDR93 AGBL2

6.28e-06169119614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXNA3 ABCA13 ITIH5 WDR93 PLXNA1 CDON

8.18e-06177119630f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 GRIK3 PKHD1L1 DNAH1 PIEZO2 CSMD1

1.02e-0518411962cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 GRIK3 PKHD1L1 DNAH1 PIEZO2 CSMD1

1.02e-051841196ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 GRIK3 PKHD1L1 DNAH1 PIEZO2 CSMD1

1.02e-0518411962b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Heart-LA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1L1 PTPN14 ZBTB39 CSGALNACT1 TRIM37 KLHL4

1.05e-0518511961ecfca049c0c1110fd1b2256db7cb7abda6afb04
ToppCellfacs-Heart-LA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1L1 PTPN14 ZBTB39 CSGALNACT1 TRIM37 KLHL4

1.05e-051851196b6df1412b579d40ed5df806f9c54bd1fbb9a1e15
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCKAP1 LAMA4 PTPN14 ZBTB39 SMARCD3 TRIM37

1.05e-051851196bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.08e-05186119640070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.12e-0518711961e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellEndothelial-B|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.15e-0518811965959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.15e-051881196c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NWD1 LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.15e-051881196524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NWD1 LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.15e-051881196d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.15e-0518811962db80767903703e7e0a1a37c598f7877a909ee94
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.15e-051881196aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DYNC2H1 LAMA4 ITIH5 PGR PIEZO2 COL14A1

1.19e-051891196203c80030df08ae112f9ae4043709f455d87ce89
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.22e-0519011968d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.22e-0519011966e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.22e-05190119691bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1L1 FRY PTPN14 ZBTB39 CSGALNACT1 KLHL4

1.30e-05192119614a816ef116aa992f86edab411f043cf7d07fe04
ToppCellfacs-Heart-LA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1L1 FRY PTPN14 ZBTB39 CSGALNACT1 KLHL4

1.30e-051921196847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCellLAM-Endothelial-LymEndo|LAM / Condition, Lineage and Cell class

LAMA4 RET PKHD1L1 PIEZO2 PTPN14 KLHL4

1.34e-05193119668eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.34e-051931196040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.34e-051931196e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A DYNC2H1 VPS13C RET MLXIPL FMN2

1.42e-0519511963e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF1A DYNC2H1 VPS13C RET MLXIPL FMN2

1.42e-0519511967796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.50e-051971196407231542fa1ffd540dcb61435c0575e71f59725
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDE8A NOL6 KDM3B ORC5 KLHL36

1.51e-051161195f2bf9599040f43b5ea8724841d7b71c0a859c016
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.55e-0519811965d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA4 PKHD1L1 PIEZO2 PTPN14 CSGALNACT1 KLHL4

1.55e-05198119699d6a64f3410dae3019161feef20a8f06081a24b
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 SPTAN1 LAMA4 RNF213 CSGALNACT1 SEC14L1

1.64e-052001196dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NCKAP1 SPTAN1 ITIH5 FRY CSGALNACT1 SEC14L1

1.64e-052001196b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCellpdx-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SPTAN1 TERF2IP IQCA1L PPP2R2A PTPN14

4.27e-0514411950b94d978262a826c9254145aa98c6c30240243f9
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA3 PGR SLC9C1 SMARCD3 CSMD1

4.56e-0514611952ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9|TCGA-Colorectal / Sample_Type by Project: Shred V9

GRIK3 NLGN1 PGR FMN2 CDON

6.83e-051591195f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCellEndothelial-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PKHD1L1 PTPN14 CSGALNACT1 KLHL4

8.14e-051651195b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF1A GRIK3 RET FMN2 GREB1

8.61e-051671195c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

IL12RB2 NLGN1 HEATR1 CD101 GNL1

8.86e-0516811952781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCelldroplet-Fat-Bat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN12 VPS13C TLR5 FUT4 ESPL1

8.86e-0516811956fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCelldroplet-Fat-Bat-18m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN12 VPS13C TLR5 FUT4 ESPL1

8.86e-051681195794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCelldroplet-Fat-Bat-18m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSCAN12 VPS13C TLR5 FUT4 ESPL1

8.86e-0516811951e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCellEndothelial-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

8.86e-0516811954977c3837fbb1f36c89fddd5764e37290ac25ad8
ToppCellEndothelial-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

9.11e-05169119595c617143e1fbdd1d55a93ffdcc210e0be37cf2f
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF1A GRIK3 RET FMN2 GREB1

9.11e-051691195b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 VEPH1 NLGN1 PKHD1L1 DNAH1

9.11e-05169119512bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

9.90e-051721195d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellBronchial_Biopsy-Endothelial-Lymphatic|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA4 PKHD1L1 ITIH5 PIEZO2 CSGALNACT1

9.90e-051721195c41f5a66781bbf63afce7ca5d118cc6d8e0fe0bc
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.02e-041731195dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellEndothelial-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.02e-041731195a81992965137195d20fc498f750975303961a828
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-regulatory_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZKSCAN5 PIK3CD CD101 NUP133 SMARCD3

1.07e-041751195a2adaa09f37e3db5d819e56ed402fe04b72abeb2
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF213 SAMD9L SMARCD3 TRIM38 TARBP1

1.07e-04175119597616bb5c127284aa9e67bc336dfcf29e137164b
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MUC16 LRRC2 PKHD1L1 BCAR3 ESPL1

1.07e-0417511953b5346fba617292de71963b6175e85a4f182fe30
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 PKHD1L1 ITIH5 GCNT7 UGGT2

1.07e-0417511950801cccec6915aefc135262fc74580280fd51aa5
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Regulatory_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZKSCAN5 PIK3CD CD101 NUP133 SMARCD3

1.07e-04175119559a8481a3b4ed63b137baea25bc02f2078dc3ac7
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 PKHD1L1 ITIH5 GCNT7 UGGT2

1.07e-04175119509163e7030f76d706eccabdb1d5ec45f8412aa75
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZFC3H1 LRP8 MREG ORC5 TMEM39A

1.10e-04176119524b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MUC16 LRRC2 PKHD1L1 BCAR3 ESPL1

1.10e-041761195dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.10e-04176119598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.10e-041761195c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZFC3H1 LRP8 MREG ORC5 TMEM39A

1.13e-041771195f360f7099570d248531897b96e0de282e58f59e9
ToppCellRV-11._Adipocyte|World / Chamber and Cluster_Paper

LAMA4 ITIH5 MREG FRMD4A MLXIPL

1.13e-041771195f0edf04930692418953e4f00a917257804ec0ffd
ToppCell3'_v3-lymph-node_spleen-Mast-Mast_cell_lympho|lymph-node_spleen / Manually curated celltypes from each tissue

ZSCAN12 NCKAP1 NCAPH2 LRP8 GCNT7

1.13e-04177119553040dbeb18574a48e352e4bce252c7c3018762c
ToppCellRV-11._Adipocyte|RV / Chamber and Cluster_Paper

LAMA4 ITIH5 MREG FRMD4A MLXIPL

1.16e-041781195278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.16e-041781195c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.16e-041781195ad3de3e03a401dac64431a541899445262246347
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 NPEPPS MUC16 CHD2 PLEKHN1

1.19e-0417911956e965e424eebef50f0202cff75f458be395cfca1
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLEKHN1 ITIH5 DNAH1 PTPN14 COL14A1

1.22e-041801195c4068fe47408cfd899131a85fa4b7e5908926f94
ToppCellRA-11._Adipocyte|RA / Chamber and Cluster_Paper

LAMA4 ITIH5 MREG FRMD4A MLXIPL

1.22e-041801195d48a3d27357f7d184132a6805950f93080146b59
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

LRRC2 URB2 RET ITIH5 SLC9C1

1.26e-0418111954a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellRV|World / Chamber and Cluster_Paper

NRAP LAMA4 LRRC2 NLGN1 CSGALNACT1

1.26e-041811195bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 SPTAN1 RNF213 CHD2 ATM

1.26e-041811195f2315414e714ac86211546a935660c4be6e85f1b
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA2 KIF1A RET PLEKHN1 LRP8

1.29e-041821195be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.29e-04182119553c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC16 PKHD1L1 COL14A1 BCAR3 CDON

1.29e-0418211959966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.32e-0418311954d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF213 TERF2IP GALNT11 ATM KLHL4

1.32e-04183119579defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.36e-04184119503ea613e00b45c81b752c14505a0538d698f551e
ToppCell3'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIF1A GRIK3 RET ESPL1 DEUP1

1.36e-041841195d5e44c9085da2a46531ed6db1249bdd88c41b45c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC2 ITIH5 FRY PTPN14 FMN2

1.36e-0418411957294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 PKHD1L1 ITIH5 PTPN14 KLHL4

1.39e-0418511953a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.39e-0418511954a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

NWD1 DYNC2H1 MUC16 WDR93 AGBL2

1.39e-041851195f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.39e-04185119536ce23893915f5c380cca39b2c33a516edf31c3a
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA4 PKHD1L1 ITIH5 PTPN14 KLHL4

1.39e-041851195224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKHD1L1 SAMD9L PTPN14 TRIM37 KLHL4

1.43e-0418611950ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

LAMA4 PKHD1L1 PIEZO2 CSGALNACT1 KLHL4

1.43e-0418611956b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 NLGN1 PTPN14 COL14A1 CSGALNACT1

1.43e-041861195f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA4 PKHD1L1 PIEZO2 PTPN14 KLHL4

1.43e-04186119520340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 CPD NLGN1 PTPN14 CSGALNACT1

1.46e-041871195c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA4 GRIK3 PKHD1L1 PIEZO2 KLHL4

1.46e-04187119565d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA4 GRIK3 PKHD1L1 PIEZO2 KLHL4

1.46e-0418711954c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA4 GRIK3 PKHD1L1 PIEZO2 KLHL4

1.46e-0418711955274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 NPEPPS VPS13C RNF213 CHD2

1.50e-041881195ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VEPH1 LAMA4 RET ITIH5 COL14A1

1.50e-041881195aa516273cdde53c8c0295f06830972388f890c97
DrugLabetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A

USP34 ABCA2 NCAPH2 WDR19 FRMD4A ARIH2 TLR5 GREB1 ATM PLXNA1 SEC14L1

3.82e-09192115116809_DN
DrugRisperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A

ABCA2 KIF1A ZKSCAN5 FRMD4A ZBTB39 SSH3 ARIH2 GREB1 CABIN1 PLXNA1

5.76e-08195115103508_DN
DrugAcyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A

PLXNA3 KIF1A DYNC2H1 ERO1A CPD NCAPH2 URB2 ARIH2 FUT4

6.92e-0719611591543_DN
DrugLetrozole [112809-51-5]; Down 200; 14uM; MCF7; HT_HG-U133A

USP34 KIF1A SPTAN1 NCAPH2 TLR5 ATM FUT4 CDON SEC14L1

8.19e-0720011594824_DN
DrugTetrandrine [518-34-3]; Down 200; 6.4uM; MCF7; HT_HG-U133A

ABCA2 ZKSCAN5 ORC5 PTPN14 ZBTB39 ARIH2 SMARCD3 ATM

6.78e-0619511586082_DN
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

USP34 ABCA2 ZSCAN12 URB2 RET PGR PTPN14 PLXNA1

7.31e-0619711581635_UP
DrugCytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A

DYNC2H1 VPS13C SPTAN1 NCAPH2 URB2 ATP11B GREB1 ATM

7.31e-0619711586217_DN
Drug(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A

USP34 RASA2 DYNC2H1 NCAPH2 ATP11B KLHL36 PIK3CD SSH3

7.59e-0619811586500_DN
DrugBenzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A

KIF1A NCAPH2 ORC5 ARIH2 TLR5 FUT4 CABIN1 PLXNA1

8.16e-0620011583577_DN
Drugphenyltriethoxysilane

GLUD1 GLUD2

2.53e-0521152CID000013075
DrugG-3SH

GLUD1 GLUD2

2.53e-0521152CID000174237
Drugiodoacetyldiethylstilbestrol

GLUD1 GLUD2

2.53e-0521152CID006455327
Drugmethylmercuric bromide

GLUD1 GLUD2

2.53e-0521152CID000068175
Drug5-methylisophthalate

GLUD1 GLUD2

2.53e-0521152CID000068137
Drugx 1 s

GLUD1 GLUD2

2.53e-0521152CID000409694
Drugcyclohexanone

PGR GLUD1

2.53e-0521152ctd:C036468
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; HL60; HT_HG-U133A

URB2 LRP8 FRY GALNT11 PIK3CD FUT4 TCFL5

4.37e-0518511571833_DN
DrugMianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

USP34 ITIH5 PGR FRMD4A GREB1 ATM AGBL2

5.00e-0518911572231_UP
DrugTetrahydrozoline hydrochloride [522-48-5]; Down 200; 16.8uM; HL60; HT_HG-U133A

NOL6 PDZD7 NCAPH2 URB2 RET THEM6 NOC4L

5.53e-0519211572507_DN
DrugCyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A

USP34 CPD NCAPH2 GREB1 ATM FUT4 PLXNA1

5.53e-0519211573252_DN
DrugDanazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PLXNA3 DYNC2H1 SPTAN1 NCAPH2 TLR5 ATM CABIN1

5.71e-0519311575315_UP
DrugPivampicillin [33817-20-8]; Down 200; 8.6uM; MCF7; HT_HG-U133A

PLXNA3 USP34 ZSCAN12 RASA2 NCAPH2 ATM PLXNA1

5.90e-0519411573506_DN
DrugChlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; PC3; HT_HG-U133A

NCAPH2 WDR19 THEM6 ARIH2 NOC4L SMARCD3 ESPL1

5.90e-0519411571822_DN
Drugleukotoxin B (12,13-EODE); Up 200; 0.2uM; MCF7; HT_HG-U133A_EA

PDE8A VPS13C URB2 ARIH2 UGGT2 ATM CABIN1

6.09e-0519511571108_UP
DrugTacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; MCF7; HT_HG-U133A

NCKAP1 PPP2R2D DYNC2H1 URB2 SSH3 CABIN1 SEC14L1

6.09e-0519511575297_UP
DrugDicumarol [66-76-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

LAMA4 NCAPH2 ORC5 FRMD4A FUT4 CABIN1 CDON

6.09e-0519511573941_DN
DrugStachydrine hydrochloride; Down 200; 22.2uM; PC3; HT_HG-U133A

PLXNA3 ABCA2 SPTAN1 ZKSCAN5 ZBTB39 SSH3 CABIN1

6.29e-0519611574469_DN
DrugTicarcillin sodium [4697-14-7]; Down 200; 9.4uM; MCF7; HT_HG-U133A

KIF1A NCAPH2 WDR19 ARIH2 TLR5 CABIN1 PLXNA1

6.50e-0519711577185_DN
DrugPilocarpine nitrate [148-72-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A

PLXNA3 USP34 KIF1A SPTAN1 NCAPH2 SSH3 ATM

6.50e-0519711573300_DN
Drugglyceollin

PGR GLUD1 GLUD2

6.70e-05161153CID000162807
DrugNitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A

USP34 SPTAN1 CPD NCAPH2 ZBTB39 GREB1 ATM

6.71e-0519811576464_DN
DrugDiprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A

ABCA2 SPTAN1 ZKSCAN5 FRMD4A PTPN14 ARIH2 SMARCD3

6.71e-0519811571689_UP
Drugchlorpromazine hydrochloride; Down 200; 1uM; HL60; HT_HG-U133A

SPTAN1 NOL6 KDM3B FRY ZBTB39 ARIH2 SEC14L1

6.71e-0519811571158_DN
DrugBetazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A

USP34 KIF1A WDR19 KLHL36 ARIH2 CABIN1 SEC14L1

6.71e-0519811571690_DN
DrugPepstatin A [26305-03-3]; Down 200; 5.8uM; MCF7; HT_HG-U133A

USP34 NCAPH2 PGR PTPN14 KLHL36 ATM FUT4

6.71e-0519811573264_DN
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

NCAPH2 ORC5 PIK3CD SSH3 ARIH2 GREB1 ATM

6.93e-0519911576458_DN
Drug11-mercapto-1-undecanol

MREG TRIM37

7.56e-0531152CID000261824
Druglenthionine

GLUD1 GLUD2

7.56e-0531152CID000067521
Drugmildiomycin

GLUD1 GLUD2

7.56e-0531152CID000125665
Drugmethoxyethylmercury

GLUD1 GLUD2

7.56e-0531152CID000115155
Drug4-methylumbelliferyl laurate

GLUD1 GLUD2

7.56e-0531152CID000600674
Drugmethylmercuric iodide

GLUD1 GLUD2

7.56e-0531152CID000067347
Drugd-arabino-3-hexulose 6-phosphate

CPD GLUD1 GLUD2

8.11e-05171153CID000193886
Drugmethyl benzoquate

GLUD1 GLUD2

1.51e-0441152CID000026383
Drugpentenoic acid

GLUD1 GLUD2

1.51e-0441152CID000012299
Drugalpha-ketoglutaramate

GLUD1 GLUD2

1.51e-0441152CID000000048
Drugchloro acetate

FUT4 TCFL5

1.51e-0441152CID012616564
Drugureidoglycine

GLUD1 GLUD2

1.51e-0441152CID000439649
DrugIvin

GLUD1 GLUD2

1.51e-0441152CID000014083
Drug8-BDB-TADP

GLUD1 GLUD2

1.51e-0441152CID000130791
Drugcadina-3,9-diene

GLUD1 GLUD2

1.51e-0441152CID000010657
DrugAC1L9CUQ

GLUD1 GLUD2

1.51e-0441152CID000442451
Drugluxabendazole

GLUD1 GLUD2

1.51e-0441152CID000072019
DrugN-butylmaleimide

GLUD1 GLUD2

1.51e-0441152CID000239780
Drugalpha-methylglutamate

GLUD1 GLUD2

1.51e-0441152CID000095440
Drug2b E2

GLUD1 GLUD2

1.51e-0441152CID005327076
Drugglycyl-l-glutamine

GLUD1 GLUD2 TRIM37

2.35e-04241153CID000123913
Drugbathocuproine

GLUD1 GLUD2

2.50e-0451152CID000065149
DrugAC1NRA4I

GLUD1 GLUD2

2.50e-0451152CID005287695
Drugisosteviol lactone

GLUD1 GLUD2

2.50e-0451152CID000401559
Drug1-pheg

GLUD1 GLUD2

2.50e-0451152CID000152041
Drug5'-FSBAzA

GLUD1 GLUD2

2.50e-0451152CID000130430
Drugadenine N1-oxide

GLUD1 GLUD2

2.50e-0451152CID000093557
Drugcholine sulfate

GLUD1 GLUD2

2.50e-0451152CID000000485
Drugl-413

GLUD1 GLUD2

2.50e-0451152CID000012475
Drug3-aminopicolinate

GLUD1 GLUD2

2.50e-0451152CID000073836
Drug(-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; HL60; HT_HG-U133A

NOL6 URB2 NOC4L FUT4 CABIN1 PLXNA1

2.92e-0417811562977_DN
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

USP34 SPTAN1 WDR19 FRY PIK3CD TLR5

3.10e-0418011562639_UP
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

PLXNA3 KIF1A SPTAN1 WDR19 PIK3CD TLR5

3.10e-0418011566579_UP
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

SPTAN1 PGR GREB1 CSGALNACT1 CDON SEC14L1

3.39e-0418311565221_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A

USP34 URB2 LRP8 FRY PIK3CD ATM

3.49e-0418411561835_DN
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

DYNC2H1 NCAPH2 ATP11B GREB1 ATM FUT4

3.69e-0418611563279_DN
DrugLycorine hydrochloride [2188-68-3]; Down 200; 12.4uM; MCF7; HT_HG-U133A

ABCA2 KIF1A SPTAN1 RET LRP8 CABIN1

3.69e-0418611566051_DN
Drugalpha-monofluoromethylputrescine

GLUD1 GLUD2

3.74e-0461152CID000134201
Drugdimethylmalonate

GLUD1 GLUD2

3.74e-0461152CID000007943
Drug2-methyl-1,2,3,4-tetrahydroisoquinoline

GLUD1 GLUD2

3.74e-0461152CID000015362
Druglanosol

GLUD1 GLUD2

3.74e-0461152CID000078659
DrugdadAB

GLUD1 GLUD2

3.74e-0461152CID000022626
DrugN-methylhydantoin

GLUD1 GLUD2

3.74e-0461152CID000069217
Drugdiazonium-1-H-tetrazole

GLUD1 GLUD2

3.74e-0461152CID000188312
DrugAC1L448Y

GLUD1 GLUD2

3.74e-0461152CID000200389
Drug2-BDB-TAMP

GLUD1 GLUD2

3.74e-0461152CID000127220
DrugEmid

GLUD1 GLUD2

3.74e-0461152CID000074798
DrugAC1L8SA5

GLUD1 GLUD2

3.74e-0461152CID000407285
Drugisodiazinon

GLUD1 GLUD2

3.74e-0461152CID000133913
Drug15d-PGJ2; Down 200; 10uM; HL60; HT_HG-U133A

ABCA2 NCAPH2 URB2 THEM6 FUT4 CABIN1

3.80e-0418711566190_DN
DrugICI 182,780; Down 200; 0.01uM; MCF7; HT_HG-U133A

USP34 ZSCAN12 RET TLR5 GREB1 CABIN1

3.80e-0418711565598_DN
DrugFlavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A

NOL6 CPD RET MREG GREB1 ATM

4.13e-0419011567405_DN
DrugDichlorodiphenyldichloroethane

LRRC2 RET PGR

4.17e-04291153ctd:D003632
DrugDilazep dihydrochloride [20153-98-4]; Up 200; 6uM; PC3; HT_HG-U133A

PLXNA3 ABCA2 SPTAN1 ZKSCAN5 ORC5 ATM

4.37e-0419211567364_UP
DrugAltretamine [654-05-6]; Down 200; 19uM; MCF7; HT_HG-U133A

ZSCAN12 ZBTB39 KLHL36 TLR5 ATM CABIN1

4.62e-0419411566467_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

KIF1A DYNC2H1 NCAPH2 URB2 ARIH2 ATM

4.62e-0419411566958_DN
DrugBepridil hydrochloride [74764-40-2]; Down 200; 10uM; MCF7; HT_HG-U133A

ZSCAN12 NCAPH2 ZBTB39 SSH3 ARIH2 CABIN1

4.62e-0419411565674_DN
DrugRapamycin; Down 200; 0.1uM; HL60; HT_HG-U133A

PDE8A KIF1A NCAPH2 NLGN1 BCAR3 CDON

4.74e-0419511562681_DN
DrugMethoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A

ZSCAN12 RET PGR ARIH2 TLR5 CABIN1

4.74e-0419511564972_UP
DrugCiprofloxacin hydrochloride [93107-08-5]; Up 200; 10.8uM; MCF7; HT_HG-U133A

ABCA2 NCKAP1 NCAPH2 SSH3 GREB1 CABIN1

4.74e-0419511565299_UP
DrugGemfibrozil [25812-30-0]; Up 200; 16uM; PC3; HT_HG-U133A

USP34 KIF1A LAMA4 ZKSCAN5 SSH3 SMARCD3

4.74e-0419511562113_UP
Drug2-propylpentanoic acid; Down 200; 500uM; MCF7; HT_HG-U133A

USP34 RASA2 SPTAN1 TMEM39B NCAPH2 SSH3

4.74e-0419511561665_DN
DrugBiperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; HL60; HT_HG-U133A

LAMA4 KLHL36 SSH3 ARIH2 PLXNA1 SEC14L1

4.74e-0419511562460_DN
DrugLiothyronine [6893-02-3]; Down 200; 6.2uM; MCF7; HT_HG-U133A

KIF1A SPTAN1 NCAPH2 ORC5 SSH3 PLXNA1

4.74e-0419511564947_DN
Diseasemigraine without aura, susceptibility to, 4, age at onset

NRAP NOL6

1.53e-0521162EFO_0004847, MONDO_0011847
Diseasefascioliasis (biomarker_via_orthology)

GLUD1 GLUD2

4.58e-0531162DOID:885 (biomarker_via_orthology)
Diseasemigraine disorder, age at onset

NRAP NOL6

4.58e-0531162EFO_0004847, MONDO_0005277
Diseasefat intake measurement

NRAP NOL6 MLXIPL

8.63e-05221163EFO_0010809
DiseaseJeune thoracic dystrophy

DYNC2H1 WDR19

9.15e-0541162cv:C0265275
Diseasesynucleinopathy (biomarker_via_orthology)

KIF1A DCTN2

9.15e-0541162DOID:0050890 (biomarker_via_orthology)
DiseaseGalloway-Mowat syndrome (is_implicated_in)

NUP107 NUP133

1.52e-0451162DOID:0080694 (is_implicated_in)
DiseaseNEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE

NUP107 NUP205 NUP133

2.22e-04301163C1868672
Diseasechildhood absence epilepsy (biomarker_via_orthology)

GLUD1 GLUD2

2.27e-0461162DOID:1825 (biomarker_via_orthology)
DiseaseHyperammonemia

GLUD1 TLR5

3.18e-0471162C0220994
Diseaseglypican-1 measurement

NRAP NOL6

3.18e-0471162EFO_0801649
Diseasecerebrospinal fluid clusterin measurement

ABCA13 NCAPH2 CSMD1

3.53e-04351163EFO_0007657
Diseaseparasitemia measurement

FRMD4A COL14A1 CSMD1

4.17e-04371163EFO_0005528
DiseaseGalloway Mowat syndrome

NUP107 NUP133

4.22e-0481162C0795949
DiseaseJeune thoracic dystrophy

DYNC2H1 WDR19

8.23e-04111162C0265275
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

PPP2R2D PPP2R2A

9.86e-04121162DOID:1441 (implicated_via_orthology)
DiseaseRenal dysplasia and retinal aplasia (disorder)

WDR19 SCLT1

9.86e-04121162C0403553
DiseaseFVC change measurement, response to placebo

KIF1A ORC5

1.16e-03131162EFO_0008344, EFO_0010339
Diseasefactor VII activating protease measurement

NRAP NOL6 KLHL36

1.34e-03551163EFO_0009368
Diseasehepatic encephalopathy (biomarker_via_orthology)

GLUD1 GLUD2

1.56e-03151162DOID:13413 (biomarker_via_orthology)
Diseaseadverse effect, response to xenobiotic stimulus

ABCA2 NLGN1 COL14A1

1.64e-03591163EFO_0009658, GO_0009410
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

PIK3CD ATM

1.77e-03161162C0334634
Diseasebitter alcoholic beverage consumption measurement

ORC5 MLXIPL CSMD1 AGBL2

1.91e-031331164EFO_0010092
Diseasesphingomyelin 22:0 measurement

HEATR1 CSMD1

2.78e-03201162EFO_0010395
DiseaseAlzheimer disease

ZSCAN12 FRMD4A FMN2 NOC4L CSMD1 CDON KLHL4

3.11e-034851167MONDO_0004975
Diseasetriacylglycerol 58:9 measurement

LRRC2 CSMD1

3.36e-03221162EFO_0010443

Protein segments in the cluster

PeptideGeneStartEntry
WIYIDNILHSRKLQN

URB2

71

Q14146
NQLYLRWSTDHATSK

CSMD1

2406

Q96PZ7
LQEWEEQHRNYVSSL

CSGALNACT1

61

Q8TDX6
TYLSADDLRINLWHL

PPP2R2A

191

P63151
RLEKTWTALRHQYTQ

BCAR3

661

O75815
RILSDTWDQNRVIHY

FBXW10

406

Q5XX13
VWLDVINHLYLLSNS

ABCA13

1396

Q86UQ4
ETYLSADDLRINLWH

PPP2R2D

196

Q66LE6
WKLHLTERADFQYSQ

ABHD17A

66

Q96GS6
VNFHWQVSEILDRYK

ARIH2

96

O95376
QSKVHQLYETIQRWS

DCTN2

306

Q13561
REWDKQEILYQTHLI

DEUP1

151

Q05D60
TSDLEQNWSLQDHYR

CCDC14

186

Q49A88
NSASKDYTLHLWNLL

NWD1

926

Q149M9
VNVLRTDSSHQAWYL

RASA2

276

Q15283
YWENTLHTLKQRQLT

NUP107

296

P57740
YIATIHSRLQDSQLW

NUP205

306

Q92621
RILSDTWDQNRVIHY

FBXW10B

406

O95170
DRQQLYWELSQLTHS

MUC16

13251

Q8WXI7
EQLYWELSQLTHNIT

MUC16

13721

Q8WXI7
HAYSWDINRALKENI

NUP133

306

Q8WUM0
KVYRWADHSSTVLQR

KLHL36

21

Q8N4N3
SWRESHLTEIRQYQQ

GREB1

466

Q4ZG55
NINLREESDWHYLQL

GREB1

1381

Q4ZG55
NHIERLWSYLTTKEL

ITIH5

571

Q86UX2
NALHLSDKVYRNSWE

NRAP

1506

Q86VF7
SQHLDYITEKLWRNA

FUT4

416

P22083
WSHLELLRKYVLASQ

GABPA

241

Q06546
NSRGNTWSRKHLYLE

LIPJ

86

Q5W064
KRHIDYSRQQISLFW

IL12RB2

331

Q99665
LHELKNLTQYSWLLD

AK3

76

Q9UIJ7
WKRLNTLAHYQVTDG

PLXNA1

1581

Q9UIW2
WKRLNSLAHYQVTDG

PLXNA3

1556

P51805
ITRSQSYLTLWEEKQ

PDZD7

431

Q9H5P4
STLRSWLQIIEANYH

PDE8A

536

O60658
WIYNEEHELVLNSLL

GALNT11

521

Q8NCW6
SHSVQFLRALWEKTQ

VEPH1

636

Q14D04
RYNTWVLQDTVLESH

NOL6

296

Q9H6R4
PIHDQSWYLDQTLRK

KDM3B

1646

Q7LBC6
SLKEQTHLREWYISN

LRRC2

116

Q9BYS8
THLREWYISNTLIQI

LRRC2

121

Q9BYS8
EKLSYFEHNLETWRQ

GNL1

166

P36915
KHYEEQQAWNITLRI

NLRP4

61

Q96MN2
EHYRANKVNLWLELV

NLGN1

636

Q8N2Q7
HYNGSSLLQWKSVRL

HECTD4

2046

Q9Y4D8
IEKYDLRTNSWLHIG

KLHL4

446

Q9C0H6
WYLETLLRQVSNGHI

NCKAP1

791

Q9Y2A7
NLHIDDQITLIQYSW

PGR

741

P06401
DELRQWYQRSTASHK

FRMD4A

926

Q9P2Q2
VLYDSWVKQLRSHNV

DNAH1

3171

Q9P2D7
AWVKANIQYSHVLER

DYNC2H1

3091

Q8NCM8
ASHLDYLVLEWLNLQ

ATM

1211

Q13315
DLLRSQLYWTHQKVT

ESPL1

861

Q14674
YWNRENSGSKLLVHL

CD101

851

Q93033
RYLEEHSAQQVDLIW

CABIN1

961

Q9Y6J0
KDIRSPEQHYWVTLN

GCNT7

306

Q6ZNI0
NRSIHEVILKNITWY

DYM

411

Q7RTS9
RNTIREYEWIHSQTK

CHD2

571

O14647
EWLKNLNHVSYGRLT

GLUD1

441

P00367
LRYNVISHDSIQISW

COL14A1

36

Q05707
IRGKWLEHSTENYLI

CDON

156

Q4KMG0
LTNLGQSTEYRHIWS

CPD

956

O75976
QSTEYRHIWSLEISN

CPD

961

O75976
THYAQVWLNISAEIR

ABCA2

486

Q9BZC7
TLRTDLYTNKHTQWF

AGBL2

291

Q5U5Z8
HLSARYLLQETWLEK

ERO1A

261

Q96HE7
ELWAHYVEELNSTQR

HEATR1

766

Q9H583
IEKYVQSVHWREALN

FRY

2271

Q5TBA9
HAILDLVQYLKWRSA

GRIK3

161

Q13003
LYWTRIQLHSKRDSS

FMN2

1296

Q9NZ56
YLHETWTQGNRLSTV

ERVFC1

36

P60507
SLTWRKQHQVDYILE

SEC14L1

301

Q92503
LESSLWELQALQRHY

NOC4L

431

Q9BVI4
AWLKRDAESIHQYLL

NPEPPS

896

P55786
EWLKNLNHVSYGRLT

GLUD2

441

P49448
ATHYWTLEKLRQRLD

KIF1A

796

Q12756
QRLYWVDSKLHQLSS

LRP8

596

Q14114
YELLSQAESWQRLHN

LAMA4

451

Q16363
NYWSISSRHVLLQEE

GOLM2

31

Q6P4E1
KSRDQHWYITQLEAA

TRIM37

411

O94972
SYLWRLEKEEQQTLS

TRIM38

196

O00635
AELDRWLYHLEKQTA

PLEKHN1

176

Q494U1
LQHWISYNEASSQLL

THEM6

181

Q8WUY1
TARKIREHLSYEDWN

SLC9C1

1006

Q4G0N8
SVNSHIYQRWKDLLQ

SAMD9L

581

Q8IVG5
YQRLWESSHATLQEL

IQCA1L

6

A6NCM1
EWQKLNYDIHTLRQV

MREG

86

Q8N565
QTVYLREISSSQWEK

ORC5

266

O43913
LATQTYIRWQELLTH

FAM178B

651

Q8IXR5
YLQRKLFSQNTVHWL

FASTKD3

646

Q14CZ7
LLSGQERTVWHLQYT

PTPN14

1061

Q15678
ALWQYVKTNRLQDSH

SMARCD3

286

Q6STE5
HDWTRKSQQYDLNAL

SEMG2

76

Q02383
AKQWQSVIRIYLDHL

WDR19

921

Q8NEZ3
VHTLRQTSLAWLDQY

MLXIPL

791

Q9NP71
LTWASHYQERLNSEQ

SSH3

226

Q8TE77
SQELVQLWNDIHYRL

ANHX

91

E9PGG2
VLYWTHVKEQLETLR

NCAPH2

391

Q6IBW4
TAIKQGYEDWLRHNS

ATP11B

101

Q9Y2G3
ENDWHRVYLVRKLSS

RNF213

4271

Q63HN8
ELSQLRIYSVNAHWE

UHRF1BP1L

146

A0JNW5
LYSLLRSEKWNHTLS

TMEM39A

436

Q9NV64
AFHQWIQETRTYLLD

SPTAN1

2216

Q13813
IILSRDNTTKYNSEW

PIEZO2

2616

Q9H5I5
NLSTIKQLLWHRAQY

PIK3CD

41

O00329
EAKLEHWYITGLRQQ

VPS13C

576

Q709C8
WQTVSQELDRLHKLY

SCLT1

151

Q96NL6
YQNRKDLSSTLWHAA

PKHD1L1

3396

Q86WI1
YLNRSLDHSSWEKLS

RET

96

P07949
ETKFFTQWQLTLHRR

ZBTB39

406

O15060
WHQDQALSSSIYLLR

ZSWIM2

21

Q8NEG5
RYKVLEQQWISHTFD

UBR3

1861

Q6ZT12
EEHWARLQRYSLSLQ

WDR93

666

Q6P2C0
ETTRISHWKDYVNVR

TRIM49D1

161

C9J1S8
NTLIQYHSIEEDKWR

STARD4

16

Q96DR4
WEYTRQQLLSHGDTK

TARBP1

1606

Q13395
DLRAEVTHWYENLQK

USP34

1236

Q70CQ2
WILRLHQGKSEDIYQ

UGGT2

1141

Q9NYU1
WVQNALLKHLDTQYS

TLR5

706

O60602
QWTTAFLKYIQERHG

TCFL5

441

Q9UL49
YTTRQDWDLRKNNTH

ZSCAN12

26

O43309
WQHIQDYTLSRKQLF

ZFC3H1

1201

O60293
SLTQHSWQSLKDRYL

TERF2IP

171

Q9NYB0
EWGHLDQSQKSLYRD

ZKSCAN5

231

Q9Y2L8
RDYLLTLRETWKQHT

TMEM39B

236

Q9GZU3