Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

PDGFB NCF1C NCF1B

1.18e-0510943GO:0016176
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

DUOX1 NCF1C NCF1B

2.16e-0512943GO:0016175
GeneOntologyMolecularFunctionAMPylase activity

FICD SELENOO

2.19e-052942GO:0070733
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

DUOX1 NCF1C NCF1B

1.09e-0420943GO:0050664
GeneOntologyMolecularFunctionclathrin adaptor activity

AP2M1 AP2A1 AP2A2

1.46e-0422943GO:0035615
GeneOntologyMolecularFunctioncargo adaptor activity

AP2M1 AP2A1 AP2A2

2.16e-0425943GO:0140312
GeneOntologyMolecularFunctionRNA polymerase III type 3 promoter sequence-specific DNA binding

BRF1 SNAPC3

3.25e-046942GO:0001006
GeneOntologyMolecularFunctionRNA polymerase III cis-regulatory region sequence-specific DNA binding

BRF1 SNAPC3

4.53e-047942GO:0000992
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

AP2M1 AP2A1 PCSK9

5.44e-0434943GO:0050750
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

ARAP3 NCF1C NCF1B

5.93e-0435943GO:0043325
GeneOntologyMolecularFunctionRNA polymerase III transcription regulatory region sequence-specific DNA binding

BRF1 SNAPC3

6.03e-048942GO:0001016
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

AP2M1 AP2A1 PCSK9

8.17e-0439943GO:0070325
GeneOntologyMolecularFunctionenzyme regulator activity

PRPSAP1 PDE8A PDGFB RASGRF2 MYCBP2 PEX12 ARHGEF17 CIT DOCK5 ARAP3 RNH1 P2RX7 SH3RF2 NCF1C NCF1B PPP1R12C

9.00e-0414189416GO:0030234
GeneOntologyMolecularFunctionRNA polymerase III general transcription initiation factor activity

BRF1 SNAPC3

1.65e-0313942GO:0000995
GeneOntologyCellularComponentendolysosome membrane

AP2M1 AP2A1 AP2A2 PCSK9

1.83e-0620954GO:0036020
GeneOntologyCellularComponentendolysosome

AP2M1 AP2A1 AP2A2 PCSK9

1.00e-0530954GO:0036019
GeneOntologyCellularComponentvesicle coat

AP2M1 AP2A1 AP2A2 KLHL12 SEC13

1.35e-0567955GO:0030120
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

DTNA RYR3 AP2M1 AP2A1 AP2A2 NCF1C NCF1B

2.18e-05185957GO:0009898
GeneOntologyCellularComponentAP-2 adaptor complex

AP2M1 AP2A1 AP2A2

3.19e-0514953GO:0030122
GeneOntologyCellularComponentclathrin coat of endocytic vesicle

AP2M1 AP2A1 AP2A2

3.98e-0515953GO:0030128
GeneOntologyCellularComponentNADPH oxidase complex

DUOX1 NCF1C NCF1B

7.06e-0518953GO:0043020
GeneOntologyCellularComponentcytoplasmic side of membrane

DTNA RYR3 AP2M1 AP2A1 AP2A2 NCF1C NCF1B

8.66e-05230957GO:0098562
GeneOntologyCellularComponentclathrin coat of coated pit

AP2M1 AP2A1 AP2A2

1.14e-0421953GO:0030132
GeneOntologyCellularComponentmembrane coat

AP2M1 AP2A1 AP2A2 KLHL12 SEC13

1.23e-04106955GO:0030117
GeneOntologyCellularComponentcoated membrane

AP2M1 AP2A1 AP2A2 KLHL12 SEC13

1.23e-04106955GO:0048475
GeneOntologyCellularComponentclathrin adaptor complex

AP2M1 AP2A1 AP2A2

3.73e-0431953GO:0030131
GeneOntologyCellularComponentclathrin vesicle coat

AP2M1 AP2A1 AP2A2

6.84e-0438953GO:0030125
GeneOntologyCellularComponentcoated vesicle

AP2M1 AP2A1 AP2A2 ASTN1 KLHL12 PCSK9 SEC13

1.28e-03360957GO:0030135
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

AP2M1 AP2A1 AP2A2

1.36e-0348953GO:0030119
GeneOntologyCellularComponentISWI-type complex

BAZ1B SMARCA1

1.79e-0314952GO:0031010
GeneOntologyCellularComponentside of membrane

DTNA RYR3 AP2M1 AP2A1 AP2A2 P2RX7 CD86 ASTN1 NCF1C NCF1B PCSK9

2.05e-038759511GO:0098552
GeneOntologyCellularComponentclathrin coat

AP2M1 AP2A1 AP2A2

2.12e-0356953GO:0030118
GeneOntologyCellularComponentCOPII vesicle coat

KLHL12 SEC13

2.35e-0316952GO:0030127
GeneOntologyCellularComponentcoated vesicle membrane

AP2M1 AP2A1 AP2A2 KLHL12 SEC13

3.01e-03215955GO:0030662
DomainARM-type_fold

SMG1 DNAJC13 CLASP2 ZYG11B MEI1 CLHC1 RYR3 DOCK5 AP2A1 AP2A2 MMS19

1.08e-063399411IPR016024
Domain-

AP2A1 AP2A2

2.51e-0529422.60.40.1030
DomainAP2_complex_asu

AP2A1 AP2A2

2.51e-052942IPR017104
DomainClathrin_a-adaptin_app_sub_C

AP2A1 AP2A2

2.51e-052942IPR003164
DomainClathrin_a-adaptin_app_Ig-like

AP2A1 AP2A2

2.51e-052942IPR013038
DomainAlpha_adaptin_C

AP2A1 AP2A2

2.51e-052942PF02296
DomainARM-like

SMG1 DNAJC13 CLASP2 ZYG11B MEI1 AP2A1 AP2A2 MMS19

6.54e-05270948IPR011989
Domain-

AP2A1 AP2A2

1.49e-0449423.30.310.30
DomainClathrin_a/coatomer_app_sub_C

AP2A1 AP2A2

1.49e-044942IPR015873
DomainCoatomer/calthrin_app_sub_C

AP2A1 AP2A2

6.88e-048942IPR009028
DomainDHC_N1

DYNC2H1 DNAH5

6.88e-048942PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH5

6.88e-048942IPR013594
DomainClathrin_a/b/g-adaptin_app_Ig

AP2A1 AP2A2

8.82e-049942IPR008152
DomainAlpha_adaptinC2

AP2A1 AP2A2

8.82e-049942PF02883
DomainAlpha_adaptinC2

AP2A1 AP2A2

8.82e-049942SM00809
Domain-

DNAJC13 CLASP2 ZYG11B AP2A1 AP2A2 MMS19

8.99e-042229461.25.10.10
Domainaa-tRNA-synt_IIb

EIF2AK4 HARS1

1.34e-0311942IPR002314
DomaintRNA-synt_2b

EIF2AK4 HARS1

1.34e-0311942PF00587
Domain-

EIF2AK4 HARS1

1.34e-03119423.40.50.800
DomainCoatomer/clathrin_app_Ig-like

AP2A1 AP2A2

1.60e-0312942IPR013041
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH5

2.19e-0314942IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH5

2.19e-0314942IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH5

2.19e-0314942IPR013602
DomainDHC_N2

DYNC2H1 DNAH5

2.19e-0314942PF08393
DomainMT

DYNC2H1 DNAH5

2.19e-0314942PF12777
DomainAAA_8

DYNC2H1 DNAH5

2.19e-0314942PF12780
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH5

2.19e-0314942IPR011704
DomainAnticodon-bd

EIF2AK4 HARS1

2.19e-0314942IPR004154
DomainAAA_5

DYNC2H1 DNAH5

2.19e-0314942PF07728
DomainDHC_fam

DYNC2H1 DNAH5

2.52e-0315942IPR026983
DomainClathrin/coatomer_adapt-like_N

AP2A1 AP2A2

2.52e-0315942IPR002553
DomainAdaptin_N

AP2A1 AP2A2

2.52e-0315942PF01602
DomainDynein_heavy_dom

DYNC2H1 DNAH5

2.52e-0315942IPR004273
DomainDynein_heavy

DYNC2H1 DNAH5

2.52e-0315942PF03028
DomainLRR_6

FBXL7 RNH1 NLRP4

2.68e-0355943PF13516
Domainaa-tRNA-synth_II

EIF2AK4 HARS1

3.64e-0318942IPR006195
DomainAA_TRNA_LIGASE_II

EIF2AK4 HARS1

3.64e-0318942PS50862
DomainLeu-rich_rpt_Cys-con_subtyp

FBXL7 RNH1

4.05e-0319942IPR006553
DomainLRR_CC

FBXL7 RNH1

4.05e-0319942SM00367
PathwayREACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION

AP2M1 AP2A1 AP2A2 PCSK9

1.28e-0616754M27761
PathwayREACTOME_VLDLR_INTERNALISATION_AND_DEGRADATION

AP2M1 AP2A1 AP2A2 PCSK9

1.28e-0616754MM15506
PathwayREACTOME_LDL_CLEARANCE

AP2M1 AP2A1 AP2A2 PCSK9

2.14e-0618754MM15565
PathwayREACTOME_LDL_CLEARANCE

AP2M1 AP2A1 AP2A2 PCSK9

2.70e-0619754M27846
PathwayREACTOME_NEF_MEDIATED_CD8_DOWN_REGULATION

AP2M1 AP2A1 AP2A2

4.99e-067753M27044
PathwayREACTOME_NEF_MEDIATED_CD4_DOWN_REGULATION

AP2M1 AP2A1 AP2A2

1.19e-059753M27011
PathwayREACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING

AP2M1 AP2A1 AP2A2

2.31e-0511753MM14694
PathwayREACTOME_PLASMA_LIPOPROTEIN_CLEARANCE

AP2M1 AP2A1 AP2A2 PCSK9

3.04e-0534754MM15566
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

AP2M1 AP2A1 AP2A2

3.07e-0512753MM15163
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2

AP2M1 AP2A1 AP2A2

3.98e-0513753M27415
PathwayREACTOME_PLASMA_LIPOPROTEIN_CLEARANCE

AP2M1 AP2A1 AP2A2 PCSK9

4.27e-0537754M27847
PathwayREACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING

AP2M1 AP2A1 AP2A2

5.05e-0514753M10122
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4

AP2M1 AP2A1 AP2A2

5.05e-0514753MM15161
PathwayREACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4

AP2M1 AP2A1 AP2A2

6.29e-0515753M27413
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

AP2M1 AP2A1 AP2A2

7.71e-0516753MM15048
PathwayREACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS

AP2M1 AP2A1 AP2A2

9.32e-0517753M5488
PathwayREACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS

AP2M1 AP2A1 AP2A2

1.80e-0421753M12347
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

AP2M1 AP2A1 AP2A2 PCSK9

3.26e-0462754MM14686
PathwayREACTOME_THE_ROLE_OF_NEF_IN_HIV_1_REPLICATION_AND_DISEASE_PATHOGENESIS

AP2M1 AP2A1 AP2A2

4.31e-0428753M11362
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

AP2M1 AP2A1 AP2A2

4.78e-0429753MM15028
PathwayWP_GABA_RECEPTOR_SIGNALING

AP2M1 AP2A1 AP2A2

5.84e-0431753M39369
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

AP2M1 AP2A1 AP2A2

5.84e-0431753M7223
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

AP2M1 AP2A1 AP2A2 PCSK9

6.75e-0475754M27032
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1C NCF1B

9.81e-049752MM14524
PathwayREACTOME_RECYCLING_PATHWAY_OF_L1

AP2M1 AP2A1 AP2A2

9.87e-0437753MM15102
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DNAJC13 DDX17 UACA DDX60 CIT OR4D2 DOCK5 ARAP3 MMS19 EIF2AK4

2.83e-10202971033005030
Pubmed

Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.

AP2M1 AP2A1 AP2A2

2.10e-08397335014951
Pubmed

A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.

AP2M1 AP2A1 AP2A2

2.10e-08397318032517
Pubmed

The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.

AP2M1 AP2A1 AP2A2

8.40e-08497312646615
Pubmed

Weak Molecular Interactions in Clathrin-Mediated Endocytosis.

AP2M1 AP2A1 AP2A2

2.09e-07597329184887
Pubmed

A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.

AP2M1 AP2A1 AP2A2

2.09e-07597317108326
Pubmed

P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice.

P2RX7 NCF1C NCF1B

2.09e-07597322343416
Pubmed

Interaction of HIV-1 Gag with the clathrin-associated adaptor AP-2.

AP2M1 AP2A1 AP2A2

2.09e-07597316139856
Pubmed

Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.

AP2M1 AP2A1 AP2A2

2.09e-07597331671891
Pubmed

Analysis of the AP-2 adaptor complex and cargo during clathrin-mediated endocytosis.

AP2M1 AP2A1 AP2A2

2.09e-07597315941406
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

DDX17 UACA BAZ1B CIT KIAA1671 AP2M1 RFLNB AP2A1 AP2A2 RNH1 SMARCA1 SEC13

3.24e-07660971232780723
Pubmed

The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites.

AP2M1 AP2A1 AP2A2

4.18e-07697312121421
Pubmed

Molecular architecture and functional model of the endocytic AP2 complex.

AP2M1 AP2A1 AP2A2

4.18e-07697312086608
Pubmed

HIV-1 Tat enters T cells using coated pits before translocating from acidified endosomes and eliciting biological responses.

AP2M1 AP2A1 AP2A2

4.18e-07697315020715
Pubmed

Cloning and characterization of mouse intestinal MUC3 mucin: 3' sequence contains epidermal-growth-factor-like domains.

ZP3 NCF1C NCF1B

7.30e-0779739494100
Pubmed

ATP-mediated killing of intracellular mycobacteria by macrophages is a P2X(7)-dependent process inducing bacterial death by phagosome-lysosome fusion.

P2RX7 NCF1C NCF1B

7.30e-07797311544318
Pubmed

ATF4 Regulates CD4+ T Cell Immune Responses through Metabolic Reprogramming.

EIF2AK4 NCF1C NCF1B

7.30e-07797329742431
Pubmed

Cloning and functional expression of the mouse homologue of p47phox.

ZP3 NCF1C NCF1B

7.30e-0779738119734
Pubmed

Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta.

AP2M1 AP2A1 AP2A2

7.30e-07797316103193
Pubmed

Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.

AP2M1 AP2A1 AP2A2

7.30e-07797323676497
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MTA2 DNAJC13 DDX17 MYCBP2 BAZ1B CMAS AP2M1 ARAP3 FBXL18 AP2A1 AP2A2 RNH1 SMARCA1 GEMIN4 MMS19 EXOC1

1.03e-061353971629467282
Pubmed

The AP-3 complex: a coat of many colours.

AP2M1 AP2A1 AP2A2 HPS5

1.11e-06289749714600
Pubmed

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef.

AP2M1 AP2A1 AP2A2

1.17e-0689732014052
Pubmed

Accessory protein recruitment motifs in clathrin-mediated endocytosis.

AP2M1 AP2A1 AP2A2

1.75e-06997312057195
Pubmed

Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance.

ZP3 NCF1C NCF1B

1.75e-06997310433265
Pubmed

Doublecortin interacts with mu subunits of clathrin adaptor complexes in the developing nervous system.

AP2M1 AP2A1 AP2A2

1.75e-06997311591131
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MTA2 SEMA3C DDX17 UACA DDX60 BAZ1B CMAS CIT KIAA1671 AP2M1 AP2A1 RNH1 SMARCA1 GEMIN4 SEC13

2.08e-061257971536526897
Pubmed

CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.

AP2M1 AP2A1 AP2A2

2.49e-061097325898166
Pubmed

Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).

BAZ1B ZP3 NCF1C NCF1B

2.79e-063597411013070
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

DYNC2H1 BAZ1B CIT FBXL7 MMS19 EXOC1 KLHL12 HARS1

3.50e-0632297826514267
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

MTA2 DNAJC13 DDX17 PDE8A MYCBP2 DYNC2H1 CLASP2 ZYG11B KIAA1671 DOCK5 AP2M1 AP2A1 AP2A2 RNH1 EXOC1

3.80e-061321971527173435
Pubmed

Generation and comparative analysis of approximately 3.3 Mb of mouse genomic sequence orthologous to the region of human chromosome 7q11.23 implicated in Williams syndrome.

BAZ1B ZP3 NCF1C NCF1B

3.90e-063897411779826
Pubmed

Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins.

AP2M1 AP2A1 AP2A2

5.89e-06139739882340
Pubmed

Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor.

AP2M1 AP2A1 AP2A2

7.49e-061497311157096
Pubmed

Effect of platelet-derived growth factor on phosphatidylcholine-hydrolyzing phospholipase D in osteoblast-like cells.

PDGFB PLCD1

7.70e-0629727664667
Pubmed

Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).

AP2A1 AP2A2

7.70e-0629722564002
Pubmed

Functional pseudogenes inhibit the superoxide production.

NCF1C NCF1B

7.70e-06297226086043
Pubmed

Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2.

AP2M1 AP2A2

7.70e-06297228003333
Pubmed

Human β Defensin-3 Increases CD86 Expression on Monocytes by Activating the ATP-Gated Channel P2X7.

P2RX7 CD86

7.70e-06297226416278
Pubmed

Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.

AP2A1 AP2A2

7.70e-06297212036598
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

MTA2 DDX17 DYNC2H1 BAZ1B CCDC39 DOCK5 FBXL7 RFLNB BRCA2 ASTN1 SEC13

8.48e-06754971135906200
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMG1 UACA RASGRF2 MYCBP2 DTNA CLASP2 EXOC1 SNAPC3 MYBPC2

1.09e-0549797923414517
Pubmed

HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.

AP2M1 AP2A1 AP2A2

1.15e-051697321762802
Pubmed

PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking.

AP2M1 AP2A1 AP2A2

1.15e-051697316055064
Pubmed

The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.

AP2M1 AP2A1 AP2A2

1.66e-051897310567358
Pubmed

Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.

AP2M1 AP2A1 AP2A2

1.66e-051897323211419
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

MTA2 DDX17 MYCBP2 CLASP2 HMGCS1 AP2M1 STXBP2 AP2A1 AP2A2 GEMIN4 MMS19 HARS1 SEC13

1.86e-051149971335446349
Pubmed

Targeting of EGFR by a combination of antibodies mediates unconventional EGFR trafficking and degradation.

AP2M1 AP2A1 AP2A2

1.97e-051997331959764
Pubmed

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway.

NDNF DYNC2H1 DTNA KIAA1671 AP2A1 AP2A2 JCHAIN

2.29e-0530297730561431
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1C NCF1B

2.31e-05397218036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1C NCF1B

2.31e-05397210678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1C NCF1B

2.31e-05397227044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1C NCF1B

2.31e-05397217167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1C NCF1B

2.31e-05397224358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1C NCF1B

2.31e-05397210891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1C NCF1B

2.31e-05397225474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1C NCF1B

2.31e-05397218787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1C NCF1B

2.31e-05397226209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1C NCF1B

2.31e-05397224873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1C NCF1B

2.31e-05397222184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1C NCF1B

2.31e-05397211018074
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1C NCF1B

2.31e-05397233545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1C NCF1B

2.31e-05397220142487
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1C NCF1B

2.31e-0539729116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1C NCF1B

2.31e-05397220686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1C NCF1B

2.31e-05397221570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1C NCF1B

2.31e-05397225565313
Pubmed

AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.

AP2A1 AP2A2

2.31e-05397222262466
Pubmed

Competition model for upregulation of the major histocompatibility complex class II-associated invariant chain by human immunodeficiency virus type 1 Nef.

AP2M1 AP2A1

2.31e-05397218524831
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1C NCF1B

2.31e-05397239357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1C NCF1B

2.31e-05397212958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1C NCF1B

2.31e-05397211435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1C NCF1B

2.31e-05397231118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1C NCF1B

2.31e-05397223482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1C NCF1B

2.31e-05397216041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1C NCF1B

2.31e-05397210085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1C NCF1B

2.31e-05397210987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1C NCF1B

2.31e-05397221435178
Pubmed

Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.

AP2A1 AP2A2

2.31e-05397226269175
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1C NCF1B

2.31e-05397218703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1C NCF1B

2.31e-05397229228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1C NCF1B

2.31e-05397217307863
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1C NCF1B

2.31e-05397222155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1C NCF1B

2.31e-05397227829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1C NCF1B

2.31e-05397224576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1C NCF1B

2.31e-05397222376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1C NCF1B

2.31e-05397223918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1C NCF1B

2.31e-05397228274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1C NCF1B

2.31e-05397226645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1C NCF1B

2.31e-05397212364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1C NCF1B

2.31e-05397224549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1C NCF1B

2.31e-05397234557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1C NCF1B

2.31e-05397228467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1C NCF1B

2.31e-05397210670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1C NCF1B

2.31e-05397220881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1C NCF1B

2.31e-05397226528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1C NCF1B

2.31e-05397219052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1C NCF1B

2.31e-05397220864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1C NCF1B

2.31e-05397223328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1C NCF1B

2.31e-05397234572995
InteractionLRRC31 interactions

DNAJC13 DDX17 UACA DDX60 CIT OR4D2 DOCK5 ARAP3 MMS19 EIF2AK4

3.69e-082059310int:LRRC31
InteractionNECAP2 interactions

SMG1 ZYG11B AP2M1 AP2A1 AP2A2

1.07e-0563935int:NECAP2
InteractionNUPR1 interactions

DDX17 UACA BAZ1B MSL1 CIT KIAA1671 AP2M1 RFLNB AP2A1 AP2A2 RNH1 SMARCA1 SEC13

1.49e-056839313int:NUPR1
InteractionNECAP1 interactions

BAZ1B AP2M1 AP2A1 AP2A2 SMARCA1

3.04e-0578935int:NECAP1
Cytoband7q11.23

BAZ1B ZP3 NCF1C NCF1B

5.58e-05979747q11.23
Cytoband12q24

CIT P2RX7

1.28e-032597212q24
Cytoband3q25.1

ANKUB1 GPR171

2.24e-03339723q25.1
Cytoband17p13

RFLNB GEMIN4

2.37e-033497217p13
Cytoband5q31.3

ARAP3 HARS1

2.66e-03369725q31.3
CytobandEnsembl 112 genes in cytogenetic band chr7q11

BAZ1B ZP3 NCF1C NCF1B

2.68e-03271974chr7q11
CoexpressionGSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_DN

RASGRF2 MSL1 HMGCS1 BBS10 BRF1 SNAPC3 PPP1R12C

1.65e-06156957M6865
ToppCellEndothelial-endothelial_cell_of_bronchial_vessel|World / Lineage, Cell type, age group and donor

PDGFB UACA RASGRF2 RUNDC3B KIAA1671 FBXL7 RFLNB

7.64e-0816597784e553d699ac56df89a77248f7308b9133e1b683
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDGFB UACA RASGRF2 RUNDC3B FBXL7 RFLNB

1.55e-06163976977a970b1296234c22178420294cea73506ee02f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PDGFB UACA RASGRF2 KIAA1671 ARAP3 RFLNB

2.94e-06182976840427d1c23d60482c943ff006b14007ed44d247
ToppCelldroplet-Fat-SCAT-30m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 KIAA1671 ARAP3 RFLNB

3.54e-06188976e901a9bdf00b8e91806f445af66647373bf62661
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 TMTC2 DOCK5 FBXL7 ST18

3.54e-0618897614072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCelldroplet-Fat-Scat-21m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 KIAA1671 ARAP3 RFLNB

3.54e-061889768671fdbc4138e6f9559920779c98628ed80f0da3
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 TMTC2 DOCK5 FBXL7 ST18

3.65e-06189976b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFB UACA RASGRF2 RUNDC3B FBXL7 ARAP3

3.65e-061899766463890d8dbee4bc198f91628a5f784970de786a
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 KIAA1671 ARAP3 RFLNB

3.76e-06190976c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 KIAA1671 ARAP3 RFLNB

3.76e-061909765174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 KIAA1671 ARAP3 RFLNB

3.76e-0619097690e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFB RASGRF2 RYR3 KIAA1671 FBXL7 ARAP3

3.88e-06191976b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRPSAP1 UACA RUNDC3B KIAA1671 FBXL7 ARAP3

4.12e-06193976e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRPSAP1 UACA RUNDC3B KIAA1671 FBXL7 ARAP3

4.12e-06193976e1d546165dcc2392f540162206852c4717d7306f
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SEMA3C GPR37 TMTC2 NXPE3 DOCK5 ST18

4.24e-06194976cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

PDGFB RASGRF2 RUNDC3B TMTC2 KIAA1671 ARAP3

4.24e-061949767b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

RASGRF2 RUNDC3B TMTC2 CCDC39 KIAA1671 ARAP3

4.37e-0619597619e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFB RASGRF2 RYR3 KIAA1671 FBXL7 ARAP3

4.63e-06197976412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

RASGRF2 RUNDC3B TMTC2 CCDC39 KIAA1671 ARAP3

4.63e-06197976f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellMacroglial-Oligodendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SEMA3C PDE8A GPR37 TMTC2 DOCK5 ST18

5.05e-062009764dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCellMacroglial-Oligodendrocytes-OPALIN--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SEMA3C PDE8A GPR37 TMTC2 DOCK5 ST18

5.05e-0620097626b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCellMacroglial-Oligodendrocytes-OPALIN---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SEMA3C PDE8A GPR37 TMTC2 DOCK5 ST18

5.05e-062009761314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCellMacroglial-Oligodendrocytes-OPALIN-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SEMA3C PDE8A GPR37 TMTC2 DOCK5 ST18

5.05e-062009768b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCellMacroglial-Oligodendrocytes-OPALIN----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SEMA3C PDE8A GPR37 TMTC2 DOCK5 ST18

5.05e-06200976272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCellMacroglial-Oligodendrocytes-OPALIN|Macroglial / cells hierarchy compared to all cells using T-Statistic

SEMA3C PDE8A GPR37 TMTC2 DOCK5 ST18

5.05e-062009765f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37 CMAS CIT TRIM10 ST18

1.12e-05134975d101e16cb87ff72c81324406fe7e3d70ed8f45df
ToppCellfacs-Heart-RV-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37 CMAS CIT TRIM10 ST18

1.12e-051349750c63c8b3c748d29c59fcb27d03276ba4f6a0d6b2
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDE8A ANKUB1 GPR37 DOCK5 ST18

1.25e-05137975ca8fdbe66a854e6283b22179ec9359ea9e86cd8e
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PDE8A ANKUB1 GPR37 DOCK5 ST18

1.34e-05139975789edd3c98e7c5c1cc402c780fded9a9dfd1dfb8
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDGFB RASGRF2 RUNDC3B ARAP3 GAREM2

2.98e-051649753cd80e6275f0f9b5667912139d15ebf5e6b17f2f
ToppCelldroplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB RASGRF2 CCDC39 HARS1 HPS5

3.25e-05167975a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CABLES2 PDGFB RUNDC3B ZP3 RFLNB

3.63e-051719751ae4b6a25bc9c1065cf5d95998ebcc70aee21ab5
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ANKUB1 CCDC39 FHAD1 DUOX1 DNAH5

3.74e-0517297508ad76412c9cc3504141797b44b88478ced87476
ToppCellCiliated_cells-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

3.74e-05172975187ae91148d293537afc77e10da2b64302322224
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX60 SKIL CCDC39 DOCK5 ARAP3

4.06e-05175975c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCellCOVID-mDC1-|COVID / Condition, Cell_class and T cell subcluster

SEMA3C SH3RF2 PLCD1 HPS5 ST18

4.06e-0517597583a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCellCOVID-mDC1|COVID / Condition, Cell_class and T cell subcluster

SEMA3C SH3RF2 PLCD1 HPS5 ST18

4.06e-05175975b9280444016e21c28131a61df65cc5c56d402412
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CLHC1 FHAD1 DNAH5

4.52e-051799755e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellIIH-CD8-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

CLHC1 FICD BRCA2 KLHL12 SNAPC3

4.64e-05180975d1a8b25115c80e5a5bd0b8244167a98250ab9778
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C UACA TMTC2 SKIL RFLNB

4.89e-05182975ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3C UACA TMTC2 SKIL RFLNB

4.89e-0518297597a805783a1f2b055c21307db250e3688674eff3
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.02e-051839755472cdce6d99314d229418412acf1fff6340db7d
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

RASGRF2 RUNDC3B TMTC2 FBXL7 ARAP3

5.02e-05183975ff95382cfed592190d0636d2b750328471f82e0d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

5.15e-051849752df903924df9cb71039159416bcbe6a6614e21fe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF UACA RYR3 DOCK5 FBXL7

5.15e-051849757294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTNA ARHGEF17 GAREM2 SMARCA1 ASTN1

5.15e-05184975f4344f3c407b2d4d703fe56e43d84dbfe60ba833
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

5.28e-051859755e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NDNF UACA RYR3 DOCK5 FBXL7

5.28e-05185975b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.28e-051859751d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.42e-0518697590eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCelldroplet-Heart-nan-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA ARAP3 RFLNB JCHAIN

5.42e-0518697549ad01d216860a2bd4d63905a7064471b02f2b37
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.42e-05186975bd8a9753df219084e19e7f94447856e86608325c
ToppCell10x5'v1-week_12-13-Lymphocytic_T-T_NK-NK_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PDGFB RUNDC3B KIAA1671 GZMM GPR171

5.42e-05186975b099cb0902e9afb11218d70407d3cab212343c6d
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.56e-05187975f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.56e-05187975b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellfacs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA TMTC2 ARAP3 RFLNB

5.70e-05188975ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

5.70e-05188975803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDGFB RASGRF2 RUNDC3B FBXL7 ARAP3

5.70e-05188975c2c51c6526defe2600302901159b8abbb58d7595
ToppCellfacs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA TMTC2 ARAP3 RFLNB

5.70e-05188975e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCelldroplet-Fat-SCAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA RASGRF2 KIAA1671 ARAP3 RFLNB

5.70e-051889755cf060bb8adaefa9964187195d67993c1248ef47
ToppCellfacs-Heart-LV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA TMTC2 ARAP3 RFLNB

5.70e-051889750fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCelldroplet-Fat-SCAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UACA RASGRF2 KIAA1671 ARAP3 RFLNB

5.70e-05188975449f9602df3c83b2110eb479a00d428d1b55b423
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDGFB UACA RUNDC3B KIAA1671 RFLNB

5.85e-05189975db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PDE8A GPR37 DOCK5 FBXL7 ST18

5.85e-0518997570eea8c94fa56bb15bee8065de47acea156794e9
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDGFB UACA RASGRF2 RUNDC3B FBXL7

5.85e-05189975fe49852ba15f948b384d6b4c258927c70b741357
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRPSAP1 UACA KIAA1671 ARAP3 P2RX7

5.85e-051899755d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 ARAP3 RFLNB

5.99e-05190975d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

5.99e-051909759ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

5.99e-05190975833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellfacs-SCAT-Fat-18m-Endothelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 ARAP3 RFLNB

5.99e-05190975b0c9dae8189d407c94964c6bfe3ef92035245357
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 ARAP3 RFLNB

5.99e-05190975dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellfacs-SCAT-Fat-18m-Endothelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 ARAP3 RFLNB

5.99e-05190975ee63dc04e91ad49aa7820c98e97261176ecebaa6
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

RASGRF2 RUNDC3B TMTC2 KIAA1671 ARAP3

5.99e-0519097578e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellfacs-SCAT-Fat-18m-Endothelial-endothelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDGFB UACA RASGRF2 ARAP3 RFLNB

5.99e-051909750e50808bfc3d0820524c8470ae3e8250819d65b2
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PDGFB RASGRF2 RUNDC3B FBXL7 ARAP3

5.99e-051909759fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCellmulticiliated|World / shred by cell class for turbinate

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.30e-051929750f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

ANKUB1 KIAA1671 FHAD1 DUOX1 DNAH5

6.30e-051929759cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.46e-051939753e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.46e-05193975e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA RUNDC3B KIAA1671 FBXL7 ARAP3

6.46e-051939756e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA RUNDC3B KIAA1671 FBXL7 ARAP3

6.46e-05193975aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.46e-05193975ea345d34440b25f65358a53dc72831998d1c3620
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UACA RASGRF2 RYR3 FBXL7 ARAP3

6.46e-051939752e72309607902dabe3218888b22a77fe941f3570
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

UACA RUNDC3B KIAA1671 FBXL7 ARAP3

6.46e-05193975c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DTNA CD86 EIF2AK4 HPS5 ST18

6.61e-05194975b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DTNA CD86 EIF2AK4 HPS5 ST18

6.61e-051949752210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MEI1 FICD JCHAIN EIF2AK4 SEC13

6.61e-051949753c30f86806f6a0f43e6103ad7009f4c6a90e011c
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PDGFB UACA RUNDC3B FBXL7 ARAP3

6.61e-0519497571ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.61e-05194975b4ce60c06568123008b1081d644733cb91c28f51
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRPSAP1 UACA RUNDC3B KIAA1671 FBXL7

6.61e-051949750b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.61e-051949757a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.61e-051949754a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.61e-05194975a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

UACA RASGRF2 RUNDC3B FBXL7 ARAP3

6.78e-051959756bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.78e-051959750e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.78e-05195975581b04220587e1d5198b1abd6965965ace7803e7
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.78e-0519597593b1559382a12cfb158aa5fac7386e38b4f87989
ToppCellNS-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.78e-0519597534e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDGFB UACA RUNDC3B KIAA1671 ARAP3

6.78e-05195975a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNC2H1 ANKUB1 CCDC39 FHAD1 DNAH5

6.78e-051959753486eae5fdb062a75a907b896c9d7b396d2aa195
DrugDelcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A

MTA2 PDGFB DTNA MTMR11 FBXL7 AP2A2 PLCD1 NCR2

1.81e-061969683613_DN
DrugEtilefrine hydrochloride [534-87-2]; Down 200; 18.4uM; MCF7; HT_HG-U133A

PDGFB DYNC2H1 DTNA BAZ1B CLASP2 HMGCS1 AP2A2 SNAPC3

1.88e-061979687350_DN
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1C NCF1B

9.98e-055942DOID:3265 (implicated_via_orthology)
DiseaseCiliopathies

DYNC2H1 CCDC39 BBS10 DNAH5

4.31e-04110944C4277690
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1C NCF1B

6.49e-0412942DOID:7148 (implicated_via_orthology)
DiseaseKartagener syndrome (implicated_via_orthology)

CCDC39 DNAH5

8.91e-0414942DOID:0050144 (implicated_via_orthology)
Diseasediffuse large B-cell lymphoma

ARAP3 CD86

8.91e-0414942EFO_0000403
Diseasephosphatidylcholine 36:3 measurement

F9 CCDC39

1.03e-0315942EFO_0010381
Diseasecolorectal mucinous adenocarcinoma

RASGRF2 PTPRA

1.17e-0316942EFO_0009361
DiseaseN-acetyl-beta-alanine measurement

RYR3 PTPRA

1.17e-0316942EFO_0021430
Diseasereticulocyte count

PRPSAP1 PEX12 TRIM10 DOCK5 PTPRA FBXL18 RNH1 OR10K2 EIF2AK4 WDSUB1

1.83e-0310459410EFO_0007986
DiseaseBronchiectasis

CCDC39 DNAH5

2.23e-0322942C0006267
DiseasePCSK9 protein measurement

FBXL18 PCSK9

3.10e-0326942EFO_0006899
Diseasemigraine disorder, pulse pressure measurement

DYNC2H1 STXBP2

3.10e-0326942EFO_0005763, MONDO_0005277

Protein segments in the cluster

PeptideGeneStartEntry
GCSVRETKSRSFDLL

ARAP3

441

Q8WWN8
TRREVEAKFCNLSLS

EIF2AK4

1236

Q9P2K8
SCVISKTARLLSSED

BAZ1B

496

Q9UIG0
RVLSFSSRVCTDIFK

GZMM

221

P51124
DFKTCVSLAVSRLSR

AP2A1

221

O95782
IFCILETDKTRLLSS

CD86

216

P42081
IFSSAKERTLCRSSL

BBS10

156

Q8TAM1
ITECSSLKRSLEQAR

CIT

511

O14578
LSRDLRKTCEEQTLS

ASTN1

1276

O14525
RTSKEAVSQRLCELL

AP2A2

921

O94973
LSITQSLCKARERET

CCDC39

66

Q9UFE4
ITASLCDLKSRLDSR

HMGCS1

401

Q01581
KVVCLFRRRDISSSL

MTA2

41

O94776
DLTATLRRAKSFTCS

ARHGEF17

536

Q96PE2
SQKVREALTCELSRA

DUOX1

791

Q9NRD9
RLACTDTSLLEFLKI

OR4D2

186

P58180
SVRKCISLFREDSTL

KIAA1671

436

Q9BY89
KEASALVCIRLVTSS

NCR2

56

O95944
RACLRKASDISVLVT

MTMR11

351

A4FU01
RLSFLKEDSQSCRVA

MMS19

491

Q96T76
RFIAKCTETTLDTLL

FICD

416

Q9BVA6
SALRLDSSRLKCTSI

HPS5

26

Q9UPZ3
LSEKFTRTCDILRIA

HPS5

1091

Q9UPZ3
TIDVRTTFSRCLSKE

DDX60

116

Q8IY21
ECKTRTEVFEISRRL

PDGFB

96

P01127
EELLSCSSFSRSGKR

PCSK9

481

Q8NBP7
EALCRSIRSSKLSEN

PDE8A

141

O60658
LVDRATCLRSTKFTI

F9

376

P00740
TEVITDCSTRISLFK

GPR171

251

O14626
TRIKAFDKLRTCSSA

NDNF

451

Q8TB73
FTLTKLSRDDIRSLC

NLRP4

701

Q96MN2
CVRLSKFDSERSISF

AP2M1

251

Q96CW1
SLSETVCKRELRSQE

MSL1

371

Q68DK7
SADLILNRCSESTKR

NCF1B

371

A6NI72
SADLILNRCSESTKR

NCF1C

346

A8MVU1
SFIRLTLELKARFCS

MEI1

601

Q5TIA1
ILASCVSEDKRISLA

OR9G4

96

Q8NGQ1
TSKILFCDVLRAIRD

PLCD1

361

P51178
CITTSELFRKLVLSR

P2RX7

506

Q99572
KLTTRFTSIVRLCSI

DYNC2H1

2416

Q8NCM8
LRKSCTEQSVISRTL

FHAD1

436

B1AJZ9
LRKSNTLCDVTLRVE

KLHL12

26

Q53G59
LFTITCSLVTARKIR

GPR37

456

O15354
TKIVESTLFRQSECR

DOCK5

861

Q9H7D0
SEDYLRLKRRCTTSL

BRCA2

3376

P51587
TVKDSIRASFSVCEL

FAM193B

561

Q96PV7
VTCISLTREASIKLS

FBXL7

251

Q9UJT9
EAFSRCVAVLTRASK

DNAJC13

1451

O75165
DLDRIRLSTYRTACK

DTNA

26

Q9Y4J8
TAACTELAKRITERL

PRPSAP1

16

Q14558
LQDLRKTACSLDART

C4orf48

61

Q5BLP8
IFATLSRLKISCLEA

EXOC1

736

Q9NV70
KCARITSRIIRSSED

JCHAIN

36

P01591
TIIFVETKRRCDDLT

DDX17

421

Q92841
FRTICSSVDKLDKVS

HARS1

231

P12081
RKRVTSQRCSLEFLE

CABLES2

121

Q9BTV7
CKRVIADRFTVSSDV

DNAH5

2826

Q8TE73
TFCALSTVLERVKAE

PTPRA

741

P18433
EFKSALCKIVRRTIS

OR10K2

296

Q6IF99
CAKTTKERSRFTTLL

GAREM2

161

Q75VX8
LITVCRFSVKTLIDR

RUNDC3B

36

Q96NL0
RFSVKTLIDRSCFET

RUNDC3B

41

Q96NL0
TRLATCSSDRSVKIF

SEC13

26

P55735
CRLSSREKISLQDLS

PPP1R12C

346

Q9BZL4
ELLSESRKTSNVCIR

SMARCA1

156

P28370
TTFLKARLVCSVTDE

SEMA3C

281

Q99985
LKTSRELCSRLDASI

SKIL

466

P12757
RLKCTTKALTEEFIS

TCP11X2

261

Q5H9J9
KSLFRSGRISETTEC

NXPE3

211

Q969Y0
VRLISERACSKQTLS

CMAS

321

Q8NFW8
CRKTLRRFLSSVELE

RFLNB

186

Q8N5W9
ERTCDKEFIIRRTAT

RASGRF2

901

O14827
QLSSECKATLSRVRE

FBXL18

161

Q96ME1
VRRLETSISSCKTSL

SMG1

3176

Q96Q15
KVLRSSIREFLCSEA

SELENOO

191

Q9BVL4
ILKRSFARTVSVECF

MYCBP2

1406

O75592
KLTQLRDSIRCVSDL

SNAPC3

211

Q92966
LCRKTRVNDTVLATS

PEX12

306

O00623
ERLVALKRVSSESFA

REELD1

281

A0A1B0GV85
LSTRCREATDILSNK

ST18

581

O60284
DKTVSDLRTLVTLRC

ANKUB1

106

A6NFN9
FIETIKKDRRTTFCL

CLHC1

81

Q8NHS4
TLSRVELKRLCEIFT

CLASP2

686

O75122
LRKAVESCSDVTRLV

ATG4D

256

Q86TL0
DRKEFETLCSELTRV

ATG4D

401

Q86TL0
TSITDITALLACKDR

ZYG11B

196

Q9C0D3
DSQRVASVSLDRCIK

WDR88

241

Q6ZMY6
RSLTKAQRDTIEECL

RYR3

2456

Q15413
RTEEARRTFLKCSEI

TMTC2

576

Q8N394
LLRTFCESKRLTTDK

STXBP2

306

Q15833
TEARCKDISSALRVN

RNH1

41

P13489
CESTLRKRLTEFEDT

BRF1

256

Q92994
ERCDKSLTTITELQR

UACA

1291

Q9BZF9
RTCKKSFSDVSVLDL

ZNF225

151

Q9UK10
LRSASEELKLSCQRT

TOPAZ1

471

Q8N9V7
LTDIRSTLIRCETRK

TRIM10

251

Q9UDY6
CLTFLKDDIITVISR

SH3RF2

211

Q8TEC5
SFSLLATCSLDKTIR

WDSUB1

21

Q8N9V3
RTTVFSEEKLTFSLR

ZP3

161

P21754
ECVRDFLRKTSTVLK

GEMIN4

381

P57678
RTRIEKRVDCSSFVI

MYBPC2

591

Q14324