Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-dependent protein kinase activity	PRKDC ATM	1.56e-04	3	145	2	GO:0004677
GeneOntologyMolecularFunction	histone H2AXS139 kinase activity	PRKDC ATM	1.56e-04	3	145	2	GO:0035979
GeneOntologyMolecularFunction	Toll-like receptor 2 binding	TLR6 TLR1	3.11e-04	4	145	2	GO:0035663
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	STARD13 GRIPAP1 RASGRF1 DOCK11 RANBP3 ADGRB3 RGS4 ARHGEF10L RAB3GAP1 RGS18 ARHGEF7 ACAP2	3.36e-04	507	145	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	STARD13 GRIPAP1 RASGRF1 DOCK11 RANBP3 ADGRB3 RGS4 ARHGEF10L RAB3GAP1 RGS18 ARHGEF7 ACAP2	3.36e-04	507	145	12	GO:0030695
GeneOntologyMolecularFunction	histone H2AX kinase activity	PRKDC ATM	5.16e-04	5	145	2	GO:0141003
GeneOntologyBiologicalProcess	meiotic chromosome segregation	RNF212 MORC2 SMC2 CEP63 MLH3 BRCA2 ATM TOP2A KNL1	2.03e-07	122	145	9	GO:0045132
GeneOntologyBiologicalProcess	homologous chromosome segregation	RNF212 MORC2 CEP63 MLH3 BRCA2 ATM KNL1	1.28e-06	78	145	7	GO:0045143
GeneOntologyBiologicalProcess	regulation of organelle organization	MYO1C TCP1 MDM1 MORC2 SMC2 RGS4 KIF20B WDPCP ARHGEF10L MAP3K4 TTBK2 SLC39A12 RAB3GAP1 VPS13D RESF1 ARHGEF7 BRD7 SNX18 WRAP73 ATM RUBCN TOP2A KNL1 TECPR1 BORA	6.92e-06	1342	145	25	GO:0033043
GeneOntologyBiologicalProcess	reciprocal meiotic recombination	RNF212 MORC2 CEP63 MLH3 ATM TOP2A	7.63e-06	67	145	6	GO:0007131
GeneOntologyBiologicalProcess	reciprocal homologous recombination	RNF212 MORC2 CEP63 MLH3 ATM TOP2A	7.63e-06	67	145	6	GO:0140527
GeneOntologyBiologicalProcess	meiotic nuclear division	RNF212 MORC2 SMC2 CEP63 MLH3 BRCA2 ATM TOP2A KNL1 TDRD12	7.88e-06	240	145	10	GO:0140013
GeneOntologyBiologicalProcess	meiosis I	RNF212 MORC2 CEP63 MLH3 BRCA2 ATM TOP2A KNL1	9.62e-06	147	145	8	GO:0007127
GeneOntologyBiologicalProcess	homologous recombination	RNF212 MORC2 CEP63 MLH3 ATM TOP2A	1.36e-05	74	145	6	GO:0035825
GeneOntologyBiologicalProcess	meiosis I cell cycle process	RNF212 MORC2 CEP63 MLH3 BRCA2 ATM TOP2A KNL1	1.42e-05	155	145	8	GO:0061982
GeneOntologyBiologicalProcess	chromosome organization involved in meiotic cell cycle	RNF212 MORC2 SMC2 CEP63 MLH3 ATM	1.47e-05	75	145	6	GO:0070192
GeneOntologyBiologicalProcess	meiotic cell cycle process	RNF212 MORC2 SMC2 CEP63 MLH3 BRCA2 ATM TOP2A KNL1 TDRD12	2.05e-05	268	145	10	GO:1903046
GeneOntologyBiologicalProcess	meiotic cell cycle	RNF212 PIWIL4 MORC2 SMC2 CEP63 MLH3 BRCA2 ATM TOP2A KNL1 TDRD12	3.84e-05	350	145	11	GO:0051321
GeneOntologyBiologicalProcess	nuclear chromosome segregation	RNF212 MORC2 SMC2 CEP63 MLH3 BRCA2 BRD7 WRAP73 ATM TOP2A KNL1	4.47e-05	356	145	11	GO:0098813
GeneOntologyBiologicalProcess	nuclear division	RNF212 MORC2 SMC2 KIF20B CEP63 MLH3 BRCA2 WRAP73 ATM TOP2A KNL1 BORA TDRD12	6.84e-05	512	145	13	GO:0000280
GeneOntologyBiologicalProcess	chromosome organization	TCP1 RNF212 MORC2 SMC2 MAP3K4 CEP63 MLH3 RESF1 BRCA2 BRD7 WRAP73 PRKDC ATM TOP2A KNL1	1.01e-04	686	145	15	GO:0051276
GeneOntologyBiologicalProcess	regulation of chromosome organization	TCP1 MORC2 SMC2 MAP3K4 RESF1 BRD7 ATM TOP2A KNL1	1.14e-04	266	145	9	GO:0033044
GeneOntologyBiologicalProcess	homologous chromosome orientation in meiotic metaphase I	BRCA2 KNL1	1.47e-04	3	145	2	GO:0031619
GeneOntologyBiologicalProcess	detection of bacterial lipopeptide	TLR6 TLR1	1.47e-04	3	145	2	GO:0070340
GeneOntologyBiologicalProcess	positive regulation of chromosome organization	TCP1 MORC2 SMC2 MAP3K4 RESF1 ATM	1.48e-04	113	145	6	GO:2001252
GeneOntologyBiologicalProcess	organelle fission	RNF212 MORC2 SMC2 KIF20B CEP63 MLH3 BRCA2 WRAP73 ATM TOP2A KNL1 BORA TDRD12	2.02e-04	571	145	13	GO:0048285
GeneOntologyBiologicalProcess	positive regulation of organelle organization	MYO1C TCP1 MORC2 SMC2 ARHGEF10L MAP3K4 TTBK2 RAB3GAP1 VPS13D RESF1 SNX18 WRAP73 ATM	2.12e-04	574	145	13	GO:0010638
GeneOntologyBiologicalProcess	activation of NF-kappaB-inducing kinase activity	TLR6 COPS8 TLR1	2.15e-04	17	145	3	GO:0007250
GeneOntologyBiologicalProcess	detection of bacterial lipoprotein	TLR6 TLR1	2.92e-04	4	145	2	GO:0042494
GeneOntologyBiologicalProcess	regulation of single stranded viral RNA replication via double stranded DNA intermediate	MORC2 RESF1 TOP2A	3.04e-04	19	145	3	GO:0045091
GeneOntologyBiologicalProcess	single stranded viral RNA replication via double stranded DNA intermediate	MORC2 RESF1 TOP2A	3.55e-04	20	145	3	GO:0039692
GeneOntologyBiologicalProcess	hematopoietic or lymphoid organ development	TET2 RC3H2 RC3H1 JAK3 PRKDC ATM	3.59e-04	133	145	6	GO:0048534
GeneOntologyBiologicalProcess	chromosome segregation	RNF212 MORC2 SMC2 CEP63 MLH3 BRCA2 BRD7 WRAP73 ATM TOP2A KNL1	4.58e-04	465	145	11	GO:0007059
GeneOntologyBiologicalProcess	microtubule-based process	CFAP47 MDM1 KIF20B WDPCP DNAH1 CEP63 CEP350 TTBK2 SLC39A12 DST BRCA2 NETO1 ARHGEF7 EHHADH CCSER2 WRAP73 BBS12 BORA	4.59e-04	1058	145	18	GO:0007017
GeneOntologyBiologicalProcess	negative regulation of T-helper cell differentiation	RC3H2 RC3H1 JAK3	4.75e-04	22	145	3	GO:0045623
GeneOntologyBiologicalProcess	presynaptic actin cytoskeleton organization	ARHGEF7 TLN2	4.84e-04	5	145	2	GO:0099140
GeneOntologyBiologicalProcess	meiotic metaphase I homologous chromosome alignment	BRCA2 KNL1	4.84e-04	5	145	2	GO:0043060
GeneOntologyBiologicalProcess	spleen development	TET2 RC3H2 RC3H1 PRKDC	4.88e-04	52	145	4	GO:0048536
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	CFAP47 MDM1 DNAH1 CEP63 CEP350 TTBK2 SLC39A12 DST BRCA2 ARHGEF7 EHHADH CCSER2 WRAP73 BORA	5.65e-04	720	145	14	GO:0000226
GeneOntologyCellularComponent	DNA repair complex	BRCA2 FANCI PRKDC ATM	1.87e-05	23	147	4	GO:1990391
GeneOntologyCellularComponent	centriole	MDM1 SFI1 CEP63 CEP350 TTBK2 WRAP73 TOP2A	2.19e-04	172	147	7	GO:0005814
Domain	PH_dom-like	RASGRF1 DOCK11 RANBP3 SH3BP2 ANKS1B ARHGEF10L JAK3 ARHGEF7 TLN2 PLCL1 ACAP2 TECPR1 PHLPP2	2.85e-05	426	145	13	IPR011993
Domain	-	RASGRF1 DOCK11 RANBP3 SH3BP2 ANKS1B ARHGEF10L ARHGEF7 TLN2 PLCL1 ACAP2 TECPR1 PHLPP2	5.54e-05	391	145	12	2.30.29.30
Domain	Secretoglobin_1C1/2	SCGB1C2 SCGB1C1	5.99e-05	2	145	2	IPR028659
Domain	Ion_trans_dom	TRPC7 TRPC6 KCND2 SCN1A KCNMA1 TRPM1	2.65e-04	114	145	6	IPR005821
Domain	Ion_trans	TRPC7 TRPC6 KCND2 SCN1A KCNMA1 TRPM1	2.65e-04	114	145	6	PF00520
Domain	HATPase_c	MORC2 MLH3 TOP2A	3.43e-04	18	145	3	SM00387
Domain	HATPase_c	MORC2 MLH3 TOP2A	4.05e-04	19	145	3	PF02518
Domain	-	MORC2 MLH3 TOP2A	4.74e-04	20	145	3	3.30.565.10
Domain	HATPase_C	MORC2 MLH3 TOP2A	5.50e-04	21	145	3	IPR003594
Domain	Toll-like_receptor	TLR6 TLR1	5.89e-04	5	145	2	IPR017241
Domain	FATC	PRKDC ATM	5.89e-04	5	145	2	PF02260
Domain	TRP_2	TRPC7 TRPC6	8.80e-04	6	145	2	PF08344
Domain	TRP_dom	TRPC7 TRPC6	8.80e-04	6	145	2	IPR013555
Domain	FAT	PRKDC ATM	8.80e-04	6	145	2	PS51189
Domain	FATC	PRKDC ATM	8.80e-04	6	145	2	PS51190
Domain	FAT	PRKDC ATM	8.80e-04	6	145	2	PF02259
Domain	PIK-rel_kinase_FAT	PRKDC ATM	8.80e-04	6	145	2	IPR003151
Domain	FATC_dom	PRKDC ATM	8.80e-04	6	145	2	IPR003152
Domain	PIK_FAT	PRKDC ATM	8.80e-04	6	145	2	IPR014009
Domain	FATC	PRKDC ATM	8.80e-04	6	145	2	SM01343
Pubmed	Unpackaging the genetics of mammalian fertility: strategies to identify the "reproductive genome".	RNF212 DNAH1 BRWD1 TDRD12	5.36e-07	16	147	4	29878059
Pubmed	Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin.	BRCA2 FANCI ATM	7.35e-07	5	147	3	15199141
Pubmed	Identification of genetic loci associated with Helicobacter pylori serologic status.	FAM114A1 TLR6 TLR1	2.56e-06	7	147	3	23652523
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 ADGRB3 SFI1 KBTBD2 CEMIP2 ARHGEF10L KMT2C DST ARHGEF7 CCSER2 RAI14 ACAP2	2.83e-06	529	147	12	14621295
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	MYO1C COPB1 TCP1 MORC2 KMT2C TLN2 TRPM1 TDRD12	3.13e-06	208	147	8	33230847
Pubmed	Real-time resolution of point mutations that cause phenovariance in mice.	KBTBD2 JAK3 PRKDC	8.69e-06	10	147	3	25605905
Pubmed	TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin.	SMC2 BRCA2 PRKDC ATM	8.82e-06	31	147	4	26095369
Pubmed	Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.	COPB1 RAB3GAP1 DST PRKDC	1.45e-05	35	147	4	22337587
Pubmed	The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.	TCP1 SMC2 RAI14 PRKDC TOP2A	1.60e-05	74	147	5	35102251
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	GRIPAP1 AMER1 TCP1 CTIF KBTBD2 ECE1 CEP350 BRCA2 KLHL7 SNX18 WRAP73 TOP2A BORA BRWD1	1.68e-05	853	147	14	28718761
Pubmed	SCGB1C1 Plays a Critical Role in Suppression of Allergic Airway Inflammation through the Induction of Regulatory T Cell Expansion.	SCGB1C2 SCGB1C1	1.77e-05	2	147	2	38892470
Pubmed	Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.	TLR6 TLR1	1.77e-05	2	147	2	22315281
Pubmed	Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.	PRKDC ATM	1.77e-05	2	147	2	11231155
Pubmed	Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.	ATM TOP2A	1.77e-05	2	147	2	23163762
Pubmed	Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.	PRKDC ATM	1.77e-05	2	147	2	10464290
Pubmed	[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].	TLR6 TLR1	1.77e-05	2	147	2	26470427
Pubmed	Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.	PRKDC ATM	1.77e-05	2	147	2	27939942
Pubmed	HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-κB pathway.	JAK3 PRKDC	1.77e-05	2	147	2	24012878
Pubmed	Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.	TLR6 TLR1	1.77e-05	2	147	2	21852947
Pubmed	The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.	PRKDC ATM	1.77e-05	2	147	2	21487018
Pubmed	Activation of DNA Damage Response Pathways during Lytic Replication of KSHV.	PRKDC ATM	1.77e-05	2	147	2	26057167
Pubmed	Mutation of epigenetic regulators TET2 and MLL3 in patients with HTLV-I-induced acute adult T-cell leukemia.	TET2 KMT2C	1.77e-05	2	147	2	26880370
Pubmed	Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.	TLR6 TLR1	1.77e-05	2	147	2	11123271
Pubmed	NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation.	NETO2 NETO1	1.77e-05	2	147	2	31044365
Pubmed	Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction.	NETO2 NETO1	1.77e-05	2	147	2	30770891
Pubmed	Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.	TLR6 TLR1	1.77e-05	2	147	2	29175392
Pubmed	A novel gene encoding a putative transmembrane protein with two extracellular CUB domains and a low-density lipoprotein class A module: isolation of alternatively spliced isoforms in retina and brain.	NETO2 NETO1	1.77e-05	2	147	2	11943477
Pubmed	DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.	PRKDC ATM	1.77e-05	2	147	2	19071136
Pubmed	The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.	TLR6 TLR1	1.77e-05	2	147	2	28474755
Pubmed	Expression of Btcl2, a novel member of Btcl gene family, during development of the central nervous system.	NETO2 NETO1	1.77e-05	2	147	2	15464227
Pubmed	NETO1 Guides Development of Glutamatergic Connectivity in the Hippocampus by Regulating Axonal Kainate Receptors.	NETO2 NETO1	1.77e-05	2	147	2	28680963
Pubmed	Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.	PRKDC ATM	1.77e-05	2	147	2	12065055
Pubmed	Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.	PRKDC ATM	1.77e-05	2	147	2	17189255
Pubmed	AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.	PRKDC ATM	1.77e-05	2	147	2	22972376
Pubmed	G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.	PRKDC ATM	1.77e-05	2	147	2	26774662
Pubmed	Metastatic Prostate Cancers with BRCA2 versus ATM Mutations Exhibit Divergent Molecular Features and Clinical Outcomes.	BRCA2 ATM	1.77e-05	2	147	2	37126020
Pubmed	Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.	TRPC7 TRPC6	1.77e-05	2	147	2	23529130
Pubmed	High expression of CPNE5 and CPNE9 predicts positive prognosis in multiple myeloma.	CPNE9 CPNE5	1.77e-05	2	147	2	33780365
Pubmed	Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma.	LAMA3 DST	1.77e-05	2	147	2	24675808
Pubmed	PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels.	TRPC7 TRPC6	1.77e-05	2	147	2	24470487
Pubmed	DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.	PRKDC ATM	1.77e-05	2	147	2	36727301
Pubmed	Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.	TLR6 TLR1	1.77e-05	2	147	2	18036178
Pubmed	The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.	TLR6 TLR1	1.77e-05	2	147	2	24445834
Pubmed	Toll-like Receptor 1 743 A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and tuberculosis: a case control study of north Indian population from Agra (India).	TLR6 TLR1	1.77e-05	2	147	2	24984237
Pubmed	Extreme Response to High-dose Testosterone in BRCA2- and ATM-mutated Prostate Cancer.	BRCA2 ATM	1.77e-05	2	147	2	27692705
Pubmed	Deciphering the role of distinct DNA-PK phosphorylations at collapsed replication forks.	PRKDC ATM	1.77e-05	2	147	2	32674014
Pubmed	SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.	TLR6 TLR1	1.77e-05	2	147	2	25261617
Pubmed	Dendritic mechanisms controlling the threshold and timing requirement of synaptic plasticity.	KCND2 KCNMA1	1.77e-05	2	147	2	20087888
Pubmed	Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.	PRKDC ATM	1.77e-05	2	147	2	21245310
Pubmed	Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer.	BRCA2 ATM	1.77e-05	2	147	2	34533610
Pubmed	The molecular causes of low ATM protein expression in breast carcinoma; promoter methylation and levels of the catalytic subunit of DNA-dependent protein kinase.	PRKDC ATM	1.77e-05	2	147	2	17593081
Pubmed	Neto auxiliary protein interactions regulate kainate and NMDA receptor subunit localization at mossy fiber-CA3 pyramidal cell synapses.	NETO2 NETO1	1.77e-05	2	147	2	24403160
Pubmed	Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation.	PRKDC ATM	1.77e-05	2	147	2	20617180
Pubmed	DNA protein kinase-dependent G2 checkpoint revealed following knockdown of ataxia-telangiectasia mutated in human mammary epithelial cells.	PRKDC ATM	1.77e-05	2	147	2	18172300
Pubmed	Structure of human Roquin-2 and its complex with constitutive-decay element RNA.	RC3H2 RC3H1	1.77e-05	2	147	2	26249698
Pubmed	A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.	TLR6 TLR1	1.77e-05	2	147	2	22778390
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TPP2 TET2 FLI1 TCP1 MED14 MORC2 SMC2 TFAP2A KMT2C RESF1 CELF1 FANCI UBTF PRKDC TOP2A KNL1	1.88e-05	1103	147	16	34189442
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 COPB1 ADGRB3 ANKS1B CPNE5 CEP63 CEP350 DST KLHL7 NETO1 MICAL2 TLN2 RAI14 PRKDC JAKMIP1 ATM BRWD1	3.27e-05	1285	147	17	35914814
Pubmed	A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.	KBTBD2 VPS13D KLHL7 COPS8 ARHGEF7	3.52e-05	87	147	5	37495603
Pubmed	Common genetic variants in candidate genes and risk of familial lymphoid malignancies.	IL12RB2 TLR6 JAK3 BRCA2 TLR1 PRKDC	3.69e-05	145	147	6	19573080
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	COPB1 TCP1 SFI1 SMC2 FANCI BRD7 TLN2 PRKDC ATM TOP2A KNL1	4.00e-05	582	147	11	20467437
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PRPSAP2 TPP2 COPB1 TCP1 MED14 MORC2 SMC2 MAP3K4 POLR3A RAB3GAP1 PRKDC TOP2A	4.81e-05	704	147	12	29955894
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TPP2 COPB1 TCP1 DPPA2 KIF20B RESF1 FANCI TRPM1 PRKDC	5.08e-05	396	147	9	26687479
Pubmed	Profiling cancer gene mutations in longitudinal epithelial ovarian cancer biopsies by targeted next-generation sequencing: a retrospective study.	ATM TOP2A	5.31e-05	3	147	2	25846551
Pubmed	BRCA2 is required for neurogenesis and suppression of medulloblastoma.	BRCA2 ATM	5.31e-05	3	147	2	17476307
Pubmed	Heterozygous Arg753Gln polymorphism of human TLR-2 impairs immune activation by Borrelia burgdorferi and protects from late stage Lyme disease.	TLR6 TLR1	5.31e-05	3	147	2	16081826
Pubmed	Study design: evaluating gene-environment interactions in the etiology of breast cancer - the WECARE study.	BRCA2 ATM	5.31e-05	3	147	2	15084244
Pubmed	Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.	PRKDC ATM	5.31e-05	3	147	2	9766667
Pubmed	Identification and characterization of FUS/TLS as a new target of ATM.	PRKDC ATM	5.31e-05	3	147	2	18620545
Pubmed	Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.	TLR6 TLR1	5.31e-05	3	147	2	18752252
Pubmed	Severe hypoxia increases expression of ATM and DNA-PKcs and it increases their activities through Src and AMPK signaling pathways.	PRKDC ATM	5.31e-05	3	147	2	30224064
Pubmed	DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.	PRKDC ATM	5.31e-05	3	147	2	18644470
Pubmed	Sublethal infection of C57BL/6 mice with Salmonella enterica Serovar Typhimurium leads to an increase in levels of Toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs.	TLR6 TLR1	5.31e-05	3	147	2	15731092
Pubmed	Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.	PRKDC ATM	5.31e-05	3	147	2	18451257
Pubmed	A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells.	MORC2 RESF1	5.31e-05	3	147	2	29728365
Pubmed	The D17Tu5 locus in the t complex: implications for the origin of t haplotypes and inbred strains.	TCP1 MAP3K4	5.31e-05	3	147	2	2569442
Pubmed	Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination.	PRKDC ATM	5.31e-05	3	147	2	23836881
Pubmed	Mutations in ATM, NBN and BRCA2 predispose to aggressive prostate cancer in Poland.	BRCA2 ATM	5.31e-05	3	147	2	32875559
Pubmed	DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.	PRKDC ATM	5.31e-05	3	147	2	27733644
Pubmed	Roquin-2 shares functions with its paralog Roquin-1 in the repression of mRNAs controlling T follicular helper cells and systemic inflammation.	RC3H2 RC3H1	5.31e-05	3	147	2	23583642
Pubmed	IFNs activate toll-like receptor gene expression in viral infections.	TLR6 TLR1	5.31e-05	3	147	2	11607792
Pubmed	Association of 4p14 TLR locus with antibodies to Helicobacter pylori.	FAM114A1 TLR6	5.31e-05	3	147	2	26312625
Pubmed	Ureaplasma parvum lipoproteins, including MB antigen, activate NF-{kappa}B through TLR1, TLR2 and TLR6.	TLR6 TLR1	5.31e-05	3	147	2	18451040
Pubmed	TLR1- and TLR6-independent recognition of bacterial lipopeptides.	TLR6 TLR1	5.31e-05	3	147	2	16455646
Pubmed	Roquin Paralogs Differentially Regulate Functional NKT Cell Subsets.	RC3H2 RC3H1	5.31e-05	3	147	2	28188245
Pubmed	A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-kappa B through TLR1, TLR2, and TLR6.	TLR6 TLR1	5.31e-05	3	147	2	16177110
Pubmed	Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) influences disease course in sarcoidosis.	TLR6 TLR1	5.31e-05	3	147	2	22150367
Pubmed	Dynamic change of histone H2AX phosphorylation independent of ATM and DNA-PK in mouse skin in situ.	PRKDC ATM	5.31e-05	3	147	2	17923115
Pubmed	DNA damage, metabolism and aging in pro-inflammatory T cells: Rheumatoid arthritis as a model system.	PRKDC ATM	5.31e-05	3	147	2	29101015
Pubmed	Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.	TRPC7 TRPC6	5.31e-05	3	147	2	28526717
Pubmed	DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.	PRKDC ATM	5.31e-05	3	147	2	31601897
Pubmed	Divergent roles of amino acid residues inside and outside the BB loop affect human Toll-like receptor (TLR)2/2, TLR2/1 and TLR2/6 responsiveness.	TLR6 TLR1	5.31e-05	3	147	2	23626692
Pubmed	Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk.	TLR6 TLR1	5.31e-05	3	147	2	15812078
Pubmed	BRCA2, ATM, and CDK12 Defects Differentially Shape Prostate Tumor Driver Genomics and Clinical Aggression.	BRCA2 ATM	5.31e-05	3	147	2	33414135
Pubmed	Epistatic effect of TLR-1, -6 and -10 polymorphisms on organic dust-mediated cytokine response.	TLR6 TLR1	5.31e-05	3	147	2	28123183
Pubmed	Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.	PRKDC ATM	5.31e-05	3	147	2	25205036
Pubmed	Zoledronate-induced S phase arrest and apoptosis accompanied by DNA damage and activation of the ATM/Chk1/cdc25 pathway in human osteosarcoma cells.	RASGRF1 ATM	5.31e-05	3	147	2	17611684
Pubmed	Screening for ATM sequence alterations in African-American women diagnosed with breast cancer.	BRCA2 ATM	5.31e-05	3	147	2	17333338
Pubmed	ATM phosphorylates histone H2AX in response to DNA double-strand breaks.	PRKDC ATM	5.31e-05	3	147	2	11571274
Pubmed	Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.	PRKDC ATM	5.31e-05	3	147	2	31164689
GeneFamily	Transient receptor potential cation channels	TRPC7 TRPC6 TRPM1	4.58e-04	28	98	3	249
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 DOCK11 SH3BP2 ARHGEF7 ACAP2 PHLPP2	8.97e-04	206	98	6	682
GeneFamily	Copines	CPNE9 CPNE5	1.02e-03	9	98	2	829
GeneFamily	CD molecules\|Toll like receptors	TLR6 TLR1	1.27e-03	10	98	2	948
GeneFamily	Secretoglobins	SCGB1C2 SCGB1C1	2.54e-03	14	98	2	734
GeneFamily	Chaperonins	TCP1 BBS12	2.92e-03	15	98	2	587
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	BRCA2 FANCI	5.19e-03	20	98	2	548
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 ARHGEF10L ARHGEF7	5.52e-03	66	98	3	722
GeneFamily	Bardet-Biedl syndrome associated\|BBSome	WDPCP BBS12	5.71e-03	21	98	2	980
GeneFamily	Regulators of G-protein signaling	RGS4 RGS18	5.71e-03	21	98	2	720
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KBTBD2 KLHL31 GZF1 KLHL7	6.09e-03	134	98	4	861
Coexpression	RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	RC3H2 SMC2 TFAP2A KIF20B CEP63 KMT2C RESF1 BRCA2 MICAL2 KCNMA1 ACAP2 TOP2A KNL1 BORA BRWD1	1.39e-05	721	147	15	M10237
Coexpression	GSE17721_LPS_VS_POLYIC_2H_BMDC_UP	TPP2 AMPD3 KBTBD2 TLR6 CYP39A1 FDFT1 TLR1 SNX18	1.80e-05	200	147	8	M3801
Coexpression	GSE20366_TREG_VS_TCONV_DN	IL12RB2 DIPK1A SFI1 ECE1 RAB3GAP1 KLHL7 MICAL2 RAI14	1.80e-05	200	147	8	M4312
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	FLI1 CPNE9 EFCAB6 DOCK11 ATAD5 ICE2 MDM1 SFI1 SMC2 CYP39A1 C8orf34 KIF20B CEMIP2 ZFHX4 BRCA2 COPS8 BRD7 TRPM1 KNL1 BORA BRWD1	2.11e-06	989	140	21	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	ATAD5 ICE2 MDM1 SMC2 C8orf34 KIF20B ZFHX4 BRCA2 BRD7 TRPM1 KNL1 BORA BRWD1	5.91e-06	432	140	13	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000	BOC FLI1 AMER1 TRPC7 TCP1 ATAD5 TRPC6 CYP39A1 CEP350 ADAMTS12 RESF1 ZFHX4 BRCA2 KCND2 KLHL7 COPS8 TOP2A LARGE1	9.27e-06	831	140	18	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500	FLI1 EFCAB6 ICE2 MDM1 SMC2 CYP39A1 TFAP2A KIF20B CEMIP2 ZFHX4 BRCA2 COPS8 FDFT1	2.34e-05	492	140	13	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlas	Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3	ATAD5 TRPC6 SMC2 KIF20B RGS18 MANSC1 BRCA2 NETO2 RAI14 TOP2A KNL1 BORA	2.45e-05	423	140	12	GSM791126_500
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#4_top-relative-expression-ranked_1000	DPPA2 SOSTDC1 PIWIL4 SFI1 JAK3 RESF1 TDRD12	3.35e-05	136	140	7	gudmap_developingGonad_e14.5_ testes_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4	ICE2 MDM1 SMC2 CYP39A1 KIF20B CEMIP2 BRCA2 FDFT1	4.17e-05	192	140	8	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlas	B cells, B.GC.Sp, CD19+ IgM+ IgD- GL7+ PNA+, Spleen, avg-3	SEMA7A ATAD5 SMC2 CYP39A1 CLEC12A KIF20B FANCI TLR1 RUBCN TOP2A KNL1	4.51e-05	380	140	11	GSM538207_500
CoexpressionAtlas	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K2	AMPD3 SEMA7A LAMA3 ECE1 LRG1 JAK3 MANSC1 GIMAP8 OSTF1	7.81e-05	270	140	9	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K2
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	BOC TPP2 IL12RB2 ATAD5 ICE2 MDM1 MED14 ANKS1B SMC2 TFAP2A KIF20B GFRA2 CEP350 BRCA2 NETO2 FDFT1 BRD7 TRPM1 ATM TOP2A KNL1 BORA BRWD1	8.17e-05	1459	140	23	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500	CPNE9 EFCAB6 DOCK11 ATAD5 MDM1 SFI1 SMC2 C8orf34 KIF20B ZFHX4 BRCA2 TRPM1	1.04e-04	492	140	12	Facebase_RNAseq_e10.5_Maxillary Arch_500
CoexpressionAtlas	B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Fetal Liver, avg-1	ATAD5 SMC2 CLEC12A KIF20B GFRA2 RGS18 BRCA2 FANCI TOP2A KNL1 BORA	1.15e-04	422	140	11	GSM538357_500
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#2_top-relative-expression-ranked_1000	STARD13 FLI1 DOCK11 MED14 KCND2 SCN1A TLR1 PLCL1	1.65e-04	234	140	8	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k2
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#2_top-relative-expression-ranked_500	DPPA2 PIWIL4 JAK3 RESF1 TDRD12	1.77e-04	79	140	5	gudmap_developingGonad_e14.5_ testes_500_k2
CoexpressionAtlas	facebase_RNAseq_e10.5_MaxArch_2500_K3	TPP2 TET2 FLI1 IL12RB2 ATAD5 ICE2 MDM1 SFI1 SMC2 TFAP2A KIF20B GFRA2 RESF1 BRCA2 NETO2 EHHADH FDFT1 BRD7 ATM KNL1	2.11e-04	1252	140	20	facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	TPP2 DOCK11 ATAD5 SMC2 KIF20B MAP3K4 CEP63 BRCA2 BRD7 PRKDC ATM BBS12	2.16e-04	532	140	12	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	BOC TPP2 IL12RB2 ATAD5 ICE2 MDM1 MED14 SMC2 KIF20B GFRA2 CEP350 BRCA2 NETO2 FDFT1 BRD7 ATM TOP2A KNL1 BORA BRWD1	2.22e-04	1257	140	20	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ATAD5 ICE2 MDM1 MED14 KIF20B BRCA2 NETO2 PRKDC KNL1	2.26e-04	311	140	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500	TPP2 FLI1 IL12RB2 ATAD5 ICE2 MDM1 SOSTDC1 SMC2 RGS4 KIF20B GFRA2 S100A3 RESF1 BRCA2 NETO2 BRD7 TRPM1 BBS12 TOP2A KNL1 BORA BRWD1	2.44e-04	1468	140	22	facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlas	FacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1	CPNE9 EFCAB6 ATAD5 MDM1 SMC2 KIF20B DST BRCA2 BRD7 PRKDC BORA	2.86e-04	469	140	11	Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000	RC3H2 AMER1 SEMA7A DOCK11 DPPA2 SMC2 ECE1 CEMIP2 RESF1 KCND2 UBTF JAKMIP1 TOP2A KNL1 TDRD12	2.86e-04	806	140	15	gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_500_k-means-cluster#3	CPNE9 EFCAB6 MDM1 SMC2 C8orf34 KIF20B BRCA2 TRPM1	2.96e-04	255	140	8	Facebase_RNAseq_e10.5_Maxillary Arch_500_K3
CoexpressionAtlas	alpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3	ATAD5 MDM1 SMC2 KIF20B BRCA2 NETO2 FANCI TOP2A KNL1 BORA	3.16e-04	398	140	10	GSM399397_500
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_1000	STARD13 BOC FLI1 DOCK11 ATAD5 MED14 KIF20B TTBK2 NETO2 KCND2 KLHL7 SCN1A TLR1 PLCL1 BRWD1	3.39e-04	819	140	15	gudmap_developingKidney_e15.5_Peripheral blastema_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	PRPSAP2 TCP1 ICE2 DPPA2 CPNE5 KMT2C BRCA2 NETO2 FANCI PRMT9 PRKDC ATM CHURC1 BRWD1 TDRD12	3.43e-04	820	140	15	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3	TRPC6 RGS18 NETO2 TOP2A KNL1	3.60e-04	92	140	5	GSM791126_100
CoexpressionAtlas	B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3	ATAD5 MDM1 SMC2 KIF20B GFRA2 BRCA2 FANCI TOP2A KNL1 BORA	3.91e-04	409	140	10	GSM399452_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	TET2 FAM114A1 AMER1 TRPC6 SOSTDC1 GFRA2 CEP350 MICAL2 TOP2A	3.99e-04	336	140	9	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlas	Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2	ATAD5 TRPC6 SMC2 KIF20B RGS18 BRCA2 NETO2 TOP2A KNL1 BORA	3.99e-04	410	140	10	GSM791122_500
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d5.VSVOva, CD8+ CD45.1+, Spleen, avg-3	ATAD5 SMC2 KIF20B GIMAP8 BRCA2 NETO2 FANCI TOP2A KNL1 BORA	3.99e-04	410	140	10	GSM538387_500
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4	COPB1 ATAD5 ICE2 MDM1 MED14 CYP39A1 BRWD1	4.05e-04	203	140	7	Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_500	RC3H2 MYO1C SEMA7A DPPA2 PIWIL4 ECE1 CEMIP2 JAK3 RESF1 TDRD12	4.07e-04	411	140	10	gudmap_developingGonad_e14.5_ testes_500
CoexpressionAtlas	Stem Cells, SC.ST34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34+, Bone marrow, avg-2	ATAD5 TRPC6 SMC2 KIF20B RGS18 BRCA2 RAI14 TOP2A KNL1 BORA	4.07e-04	411	140	10	GSM791112_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#3	BOC FLI1 FAM114A1 CPNE9 ICE2 MDM1 SMC2 KIF20B GFRA2 ZFHX4 BRCA2 FDFT1 TRPM1 KNL1 TECPR1	4.10e-04	834	140	15	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K3
CoexpressionAtlas	B cells, B.Fo.MLN, CD19+ CD45R+ CD23+ CD21/35+, Lymph Node, avg-3	GRIPAP1 MYO1C DIPK1A SH3BP2 RGS18 GIMAP8 TLR1 RUBCN BRWD1	4.53e-04	342	140	9	GSM777021_500
CoexpressionAtlas	alpha beta T cells, T.ISP.Th, 4- 8+ TCR-/lo 24hi, Thymus, avg-3	ATAD5 MDM1 SMC2 KIF20B CELF1 BRCA2 FANCI TOP2A KNL1 BORA	4.55e-04	417	140	10	GSM399403_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3	ATAD5 SMC2 KIF20B CEMIP2 RGS18 FANCI TLN2 TOP2A KNL1 BORA	4.73e-04	419	140	10	GSM476664_500
CoexpressionAtlas	alpha beta T cells, preT.DN2B.Th, Lin-/lo CD25hi CD44+ cKitint, Thymus, avg-2	IL12RB2 ATAD5 SMC2 CLEC12A RGS18 BRCA2 FANCI TOP2A KNL1 BORA	4.82e-04	420	140	10	GSM791141_500
CoexpressionAtlas	B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R+ CD, Fetal Liver, avg-2	ATAD5 SMC2 CLEC12A KIF20B GFRA2 RGS18 BRCA2 TOP2A KNL1 BORA	5.00e-04	422	140	10	GSM538355_500
CoexpressionAtlas	facebase_RNAseq_e10.5_MandArch_2500_K1	TPP2 FLI1 IL12RB2 ATAD5 ICE2 MDM1 SMC2 KIF20B GFRA2 S100A3 RESF1 BRCA2 NETO2 BRD7 BBS12 TOP2A KNL1 BORA BRWD1	5.19e-04	1241	140	19	facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	BOC TET2 FAM114A1 AMER1 SEMA7A TCP1 ATAD5 TRPC6 SOSTDC1 GFRA2 BRCA2 NETO2 MICAL2 TOP2A	5.64e-04	768	140	14	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	BOC AMER1 TRPC6 CYP39A1 CEP350 ADAMTS12 KLHL7 TOP2A LARGE1	5.80e-04	354	140	9	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	BOC TET2 FAM114A1 AMER1 SEMA7A ATAD5 TRPC6 SOSTDC1 GFRA2 CEP350 NETO2 MICAL2 FDFT1 TOP2A	6.01e-04	773	140	14	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_200	SOSTDC1 TFAP2A GFRA2 DST ZFHX4 TRPM1	6.17e-04	157	140	6	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	IL12RB2 ATAD5 ICE2 MDM1 CTIF SFI1 SMC2 KIF20B WDPCP GFRA2 CEMIP2 BRCA2 NETO2 ARHGEF7 ATM KNL1 BRWD1	6.22e-04	1060	140	17	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_1000	RC3H2 DOCK11 ICE2 DPPA2 SMC2 ECE1 KMT2C RESF1 BRCA2 KCND2 JAKMIP1 ATM CHURC1 TDRD12	6.24e-04	776	140	14	gudmap_developingGonad_e14.5_ ovary_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	EFCAB6 ICE2 SH3BP2 MDM1 CPNE5 RESF1 RAI14 TECPR1 BRWD1	6.41e-04	359	140	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	ICE2 MDM1 SMC2 KIF20B WDPCP BRCA2 FDFT1 CCSER2	7.09e-04	291	140	8	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	NK cells, NK.MCMV1.Sp, CD3-,NK1.1+, Spleen, avg-3	IL12RB2 SEMA7A ATAD5 SH3BP2 SMC2 CEMIP2 GIMAP8 TOP2A KNL1	7.50e-04	367	140	9	GSM538309_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	ATAD5 ICE2 MDM1 ADGRB3 MED14 KIF20B CEMIP2 CEP63 TTBK2 BRCA2 NETO2 ARHGEF7 PRKDC KNL1 TECPR1 BRWD1	8.26e-04	989	140	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	FLI1 CPNE9 EFCAB6 MDM1 C8orf34 KIF20B BRCA2 TRPM1	8.27e-04	298	140	8	Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlas	kidney_adult_CortVasc_Tie2_k-means-cluster#2_top-relative-expression-ranked_1000	FLI1 SEMA7A LAMA3 ECE1 VPS13D MANSC1 GIMAP8 OSTF1	9.01e-04	302	140	8	gudmap_kidney_adult_CortVasc_Tie2_k2_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	CPNE5 BRCA2 PRKDC ATM BRWD1	9.96e-04	115	140	5	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k2_1000
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ATAD5 DPPA2 SMC2 KIF20B BRCA2 NETO2 FANCI TOP2A KNL1	1.63e-08	191	148	9	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TPP2 SMC2 KIF20B CEP350 BRCA2 NETO2 FANCI TOP2A KNL1	1.87e-08	194	148	9	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell\|2m / Sample Type, Dataset, Time_group, and Cell type.	ATAD5 MDM1 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	2.43e-08	200	148	9	0d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells\|2m / Sample Type, Dataset, Time_group, and Cell type.	ATAD5 MDM1 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	2.43e-08	200	148	9	0675f580ccef705875854247bbfd4ee2bcf126a1
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	1.64e-07	180	148	8	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 SMC2 KIF20B SLC39A12 P2RX5 BRCA2 TOP2A KNL1	1.86e-07	183	148	8	a716b446c2bf5aa294b8f580aa845098fae76354
ToppCell	Dividing_Macrophages-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	1.94e-07	184	148	8	f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 LAMA3 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	2.02e-07	185	148	8	30e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	AMER1 MED14 CEP350 RAB3GAP1 VPS13D RESF1 CCSER2 CHURC1	2.11e-07	186	148	8	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	2.38e-07	189	148	8	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IL12RB2 DOCK11 ATAD5 SMC2 KIF20B RESF1 TOP2A KNL1	2.58e-07	191	148	8	912e2d10d3423aa7f708fcf2b11da1845f12d7d3
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATAD5 SMC2 KIF20B BRCA2 FANCI JAKMIP1 TOP2A KNL1	2.58e-07	191	148	8	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Prolif_T\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IL12RB2 DOCK11 ATAD5 SMC2 KIF20B RESF1 TOP2A KNL1	2.58e-07	191	148	8	77a2746b6d9c53b08d4405411c16fcc5a6c734ce
ToppCell	Severe_COVID-19-Myeloid-proliferating_Myeloid_cells\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.80e-07	193	148	8	0d85025690c9cd545cba30abc38acbdd6a39b153
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.91e-07	194	148	8	cb39850e9577015b6b9834e98c36b412bae7d462
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.91e-07	194	148	8	408597c9aa302a44b112c1d612c21fbb0227a82a
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.91e-07	194	148	8	193cc20fefbd795a4ad59e401a95af47d30603e7
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.91e-07	194	148	8	2360b5f995b360419de41612368cab9fb61781a1
ToppCell	BAL-Severe-Myeloid-Myeloid-proliferating_Myeloid_cells\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.91e-07	194	148	8	903ae11708b0cb24538c6982abd57fe6fa95b8d3
ToppCell	BAL-Severe-Myeloid-Myeloid\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ATAD5 ADGRB3 SMC2 KIF20B DST FANCI TOP2A KNL1	2.91e-07	194	148	8	58406502a8cbcc3037f79a1b6a683df408297ae5
ToppCell	proximal-Hematologic-Proliferating_Macrophage\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CPNE9 ATAD5 SMC2 BRCA2 NETO2 FANCI TOP2A KNL1	3.27e-07	197	148	8	0b1fa881abbfcc54b322fc27124db3f8947af016
ToppCell	proximal-3-Hematologic-Proliferating_Macrophage\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CPNE9 ATAD5 SMC2 BRCA2 NETO2 FANCI TOP2A KNL1	3.27e-07	197	148	8	0dd9058aa19d1268ebba9a65555870224b5a5978
ToppCell	proximal-Hematologic-Proliferating_Macrophage-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CPNE9 ATAD5 SMC2 BRCA2 NETO2 FANCI TOP2A KNL1	3.27e-07	197	148	8	9243617b307acf3df40d93c41cd8d4788699a7ea
ToppCell	critical-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TPP2 KIF20B CEP350 BRCA2 NETO2 FANCI TOP2A KNL1	3.67e-07	200	148	8	f39db4250ce220a3eb58edee3f7fc3671701d46f
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	3.67e-07	200	148	8	cea58274efbe7f9e3c3ef9fbb768ebfb917e21d9
ToppCell	Non-neuronal-Dividing-IPC\|World / Primary Cells by Cluster	ATAD5 SMC2 KIF20B ZFHX4 BRCA2 TOP2A KNL1 BORA	3.67e-07	200	148	8	971533181daa1bfac1f1b8c507d2013f891f9078
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA7A PIWIL4 TLR6 CPNE5 RESF1 P2RX5 PARP15	1.20e-06	162	148	7	fc313fb2c55957faa8c9ca4023b3fce63527c267
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA7A PIWIL4 TLR6 CPNE5 RESF1 P2RX5 PARP15	1.20e-06	162	148	7	002fac3c5c3030950f9eb9e887d59902586d8452
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA7A PIWIL4 TLR6 CPNE5 RESF1 P2RX5 PARP15	1.20e-06	162	148	7	08b7f06580d516307516d5475a5dae0fa040f1a4
ToppCell	3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_B-B_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEMA7A PIWIL4 TLR6 CPNE5 RESF1 P2RX5 PARP15	1.20e-06	162	148	7	1fda21a303a08aff6f97819cd8766cd18784d8bc
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMC2 LRG1 CLEC12A RESF1 TLN2 TOP2A KNL1	1.47e-06	167	148	7	1bd27ffe381d26731b6d4cc5f29b27f1bac4473b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ATAD5 KIF20B BRCA2 FANCI TOP2A KNL1	1.47e-06	167	148	7	bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 DPPA2 BRCA2 NETO2 FANCI TOP2A KNL1	1.60e-06	169	148	7	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	1.60e-06	169	148	7	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 SMC2 KIF20B SLC39A12 BRCA2 TOP2A KNL1	1.73e-06	171	148	7	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATAD5 MDM1 MED14 SMC2 FDFT1 TOP2A KNL1	1.79e-06	172	148	7	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRPC6 SMC2 RGS4 KIF20B TOP2A KNL1 BORA	2.01e-06	175	148	7	3e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	2.01e-06	175	148	7	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLI1 SMC2 ECE1 KIF20B TOP2A KNL1 BORA	2.09e-06	176	148	7	8385435074cc5235b7af7424974f609388fc2cff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 LAMA3 BRCA2 FANCI PRKDC TOP2A KNL1	2.34e-06	179	148	7	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_3\|368C / Donor, Lineage, Cell class and subclass (all cells)	IL12RB2 RC3H2 DIPK1A ANKS1B KIF20B JAK3 MICAL2	2.52e-06	181	148	7	b193f3606554adc55c5906219d114288bb1f978a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	2.61e-06	182	148	7	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	2.71e-06	183	148	7	a48a6313f2f144586951cece97ec31f6d72361df
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA EFCAB6 ABCA12 SFI1 DNAH1 ZFHX4 TLN2	2.81e-06	184	148	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA EFCAB6 ABCA12 SFI1 DNAH1 ZFHX4 TLN2	2.81e-06	184	148	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA EFCAB6 ABCA12 SFI1 DNAH1 ZFHX4 TLN2	2.81e-06	184	148	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	SMC2 KIF20B P2RX5 BRCA2 FANCI TOP2A KNL1	2.91e-06	185	148	7	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD8-positive,_alpha-beta_T_cell\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	2.91e-06	185	148	7	9d424a8608b339dd6129c58d87626678d4ec4af7
ToppCell	Dividing_Macrophages-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	OTOA SMC2 KIF20B FANCI KCNMA1 TOP2A KNL1	3.01e-06	186	148	7	0067eb78d4c7e32b9563550d9fcaf13445ee6a48
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	RNF212 CLEC12A KLHL31 S100A3 KCNMA1 TOP2A KNL1	3.01e-06	186	148	7	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 KIF20B ADAMTS12 BRCA2 FANCI TOP2A KNL1	3.12e-06	187	148	7	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 KIF20B ADAMTS12 BRCA2 FANCI TOP2A KNL1	3.12e-06	187	148	7	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 LAMA3 KIF20B BRCA2 FANCI TOP2A KNL1	3.12e-06	187	148	7	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.12e-06	187	148	7	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	GRIPAP1 CPNE5 C8orf34 FAM135B CELF1 NETO1 JAKMIP1	3.23e-06	188	148	7	e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCell	NS-critical-d_0-4-Lymphoid-NKT-proliferating\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.35e-06	189	148	7	d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D231\|Adult / Lineage, Cell type, age group and donor	ELAPOR2 RASGRF1 C8orf34 MICAL2 SCN1A RAI14 LARGE1	3.35e-06	189	148	7	dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCell	Dividing_Macrophages-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.35e-06	189	148	7	d4e88a3e50499d683e3db38aee04490146fe30bb
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	ATAD5 SMC2 BRCA2 FANCI PRKDC TOP2A KNL1	3.47e-06	190	148	7	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPNE9 KIF20B BRCA2 NETO2 FANCI TOP2A KNL1	3.59e-06	191	148	7	d6e158f16a183c9203c057192342e9b83e79bc89
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPNE9 KIF20B BRCA2 NETO2 FANCI TOP2A KNL1	3.59e-06	191	148	7	7cb5c6f2cf27f3503d1b313e402a7410dfe6473e
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4/8-lo-Cycling_T\|bone_marrow / Manually curated celltypes from each tissue	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.59e-06	191	148	7	210a0f1a71df2508cbfc73d6868a2122338b9a1c
ToppCell	Mild-T/NK_proliferative\|World / Disease group and Cell class	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.59e-06	191	148	7	9dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCell	RV-08._Macrophage\|World / Chamber and Cluster_Paper	FLI1 DOCK11 CLEC12A BRCA2 KCNMA1 TOP2A KNL1	3.72e-06	192	148	7	a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	TPP2 SFI1 MAP3K4 JAK3 LINS1 CCSER2 PLCL1	3.72e-06	192	148	7	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ELAPOR2 RASGRF1 C8orf34 MICAL2 SCN1A RAI14 LARGE1	3.72e-06	192	148	7	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ELAPOR2 RASGRF1 C8orf34 MICAL2 SCN1A RAI14 LARGE1	3.85e-06	193	148	7	fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ATAD5 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	3.85e-06	193	148	7	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	ELAPOR2 RASGRF1 C8orf34 MICAL2 SCN1A RAI14 LARGE1	3.85e-06	193	148	7	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ATAD5 PIWIL4 LRG1 BRCA2 FANCI TOP2A KNL1	3.85e-06	193	148	7	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ELAPOR2 RASGRF1 C8orf34 MICAL2 SCN1A RAI14 LARGE1	3.85e-06	193	148	7	f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ATAD5 SMC2 BRCA2 FANCI JAKMIP1 TOP2A KNL1	3.98e-06	194	148	7	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	SMC2 CYP39A1 CLEC12A KIF20B FDFT1 TOP2A KNL1	3.98e-06	194	148	7	4a207630d72059345b10010f5cfd3b1462458324
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.98e-06	194	148	7	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ATAD5 SMC2 BRCA2 FANCI JAKMIP1 TOP2A KNL1	3.98e-06	194	148	7	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ATAD5 PIWIL4 LRG1 BRCA2 FANCI TOP2A KNL1	3.98e-06	194	148	7	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ATAD5 SMC2 BRCA2 FANCI JAKMIP1 TOP2A KNL1	3.98e-06	194	148	7	635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|367C / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	3.98e-06	194	148	7	a12b64945e10f00aa983678a02586c59badc1570
ToppCell	COVID-19-kidney-Proliferating_T_cell\|kidney / Disease (COVID-19 only), tissue and cell type	SMC2 KIF20B BRCA2 FANCI JAKMIP1 TOP2A KNL1	4.12e-06	195	148	7	7e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SMC2 KIF20B RGS18 BRCA2 FANCI TOP2A KNL1	4.12e-06	195	148	7	db1660ce74819cd816bdcfcae5efb3aad82cce66
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.12e-06	195	148	7	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.12e-06	195	148	7	926eb3fc5d028be936885bea0654a77db3107234
ToppCell	mild-Lymphocytic-Prol._cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.12e-06	195	148	7	9a8cc9097a349fd0a53ccf2723ee8bb1418d6aca
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.12e-06	195	148	7	1a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL12RB2 ATAD5 SMC2 BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	76f581e35967f8f7c85a8556129f6e8042ad11ca
ToppCell	367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	9591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SMC2 KIF20B BRCA2 FANCI TOP2A KNL1 BORA	4.26e-06	196	148	7	5905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	ATAD5 KIF20B ADAMTS12 BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI PRKDC TOP2A	4.26e-06	196	148	7	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	1d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell	cycling_basal_cell\|World / shred by cell class for nasal brushing	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	aa7bac70a2fe4a3cb28d89fa1a87c68c2ead1349
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	1964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	73f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STARD13 FLI1 DOCK11 GFRA2 RGS18 TLR1 KCNMA1	4.26e-06	196	148	7	cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATAD5 KIF20B ADAMTS12 BRCA2 FANCI TOP2A KNL1	4.26e-06	196	148	7	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	ICU-SEP-Lymphocyte-T_NK-T_NK_proliferative\|ICU-SEP / Disease, Lineage and Cell Type	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.40e-06	197	148	7	908e91fa16134b61943aea5e8fc0d6fbac8a8c6e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 DOCK11 CLEC12A GFRA2 RGS18 TLR1 KCNMA1	4.40e-06	197	148	7	6ca6e17b7cc5f7ea8d4b6ca1ff670969bee65a45
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.40e-06	197	148	7	84ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCell	mild_COVID-19-B_intermediate\|mild_COVID-19 / disease group, cell group and cell class (v2)	MYO1C SEMA7A CPNE5 P2RX5 NETO1 PARP15 LARGE1	4.40e-06	197	148	7	f669500120646f69355a6f920b892a6f2faeab63
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ATAD5 SMC2 KIF20B BRCA2 FANCI TOP2A KNL1	4.40e-06	197	148	7	8b616cde333bdbc0c591035ad9e4949155866245
Drug	haloperidol; Down 200; 10uM; MCF7; HT_HG-U133A	STARD13 RC3H2 ATAD5 RANBP3 CEMIP2 LINS1 RAB3GAP1 VPS13D BRCA2 BRWD1	5.77e-07	199	144	10	6963_DN
Drug	2,4,4'-trichlorobiphenyl	TRPC7 CPNE9 DOCK11 ATAD5 ICE2 ANKS1B SOSTDC1 SMC2 KIF20B GFRA2 GIMAP8 ZFHX4 CELF1 BRCA2 KCND2 ARHGEF7 MICAL2 FANCI SCN1A KCNMA1 TLN2 ATM CHURC1 TOP2A BORA	2.62e-06	1411	144	25	ctd:C081766
Drug	2,4,5,2',5'-pentachlorobiphenyl	TRPC7 CPNE9 DOCK11 ATAD5 ICE2 ANKS1B SOSTDC1 SMC2 KIF20B GFRA2 GIMAP8 ZFHX4 CELF1 BRCA2 KCND2 ARHGEF7 MICAL2 FANCI SCN1A KCNMA1 TLN2 ATM CHURC1 TOP2A BORA	3.80e-06	1441	144	25	ctd:C009828
Drug	phentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA	TPP2 RC3H2 ATAD5 MED14 RAB3GAP1 VPS13D MICAL2 TOP2A BRWD1	4.33e-06	195	144	9	1138_DN
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	TPP2 MDM1 ARHGEF10L SLC9A2 ARHGEF7 MICAL2 CCSER2 WRAP73 ATM	4.71e-06	197	144	9	6975_DN
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A	ATAD5 MED14 VPS13D MICAL2 CCSER2 PRKDC ATM BRWD1	3.01e-05	191	144	8	4168_DN
Drug	Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; HL60; HT_HG-U133A	TRPC7 EFCAB6 RASGRF1 LAMA3 ECE1 CYP39A1 SLC9A2 TRPM1	3.49e-05	195	144	8	3028_UP
Drug	Triamterene [396-01-0]; Down 200; 15.8uM; HL60; HT_HG-U133A	FLI1 KIF20B RAB3GAP1 VPS13D CELF1 ARHGEF7 TOP2A BRWD1	3.62e-05	196	144	8	1861_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	STARD13 MED14 LAMA3 SFI1 SMC2 MAP3K4 VPS13D UBTF	3.76e-05	197	144	8	6222_DN
Drug	Bucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	DIPK1A MORC2 ECE1 TFAP2A CEP63 TTBK2 VPS13D BRWD1	3.76e-05	197	144	8	5886_DN
Drug	troglitazone; Down 200; 10uM; MCF7; HT_HG-U133A_EA	RC3H2 MED14 KIF20B VPS13D RESF1 CELF1 BRCA2 ATM	3.89e-05	198	144	8	1070_DN
Drug	Asiaticoside [16830-15-2]; Down 200; 4.2uM; HL60; HT_HG-U133A	STARD13 TCP1 SH3BP2 ECE1 ARHGEF10L LINS1 MLH3 UBTF	3.89e-05	198	144	8	2943_DN
Drug	Pergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	SH3BP2 MED14 SFI1 CEMIP2 ARHGEF10L COPS8 ARHGEF7 TLN2	3.89e-05	198	144	8	7031_DN
Drug	(R)-Propranolol hydrochloride [13071-11-9]; Up 200; 13.6uM; PC3; HT_HG-U133A	FLI1 RC3H2 AMPD3 ATAD5 CTIF TFAP2A KCNMA1 TLN2	3.89e-05	198	144	8	5814_UP
Drug	DL-PPMP; Up 200; 2uM; MCF7; HT_HG-U133A_EA	MDM1 MED14 CEP63 RESF1 KLHL7 CCSER2 WRAP73 ATM	3.89e-05	198	144	8	1121_UP
Drug	Benzocaine [94-09-7]; Down 200; 24.2uM; MCF7; HT_HG-U133A	RC3H2 RANBP3 MED14 TTBK2 VPS13D BRCA2 COPS8 TLN2	3.89e-05	198	144	8	4808_DN
Drug	tertiary carboxamide	BOC DST	3.97e-05	2	144	2	CID006419719
Drug	3,5-cholestadien-7-one	CYP39A1 NETO1	3.97e-05	2	144	2	CID000011280
Drug	Corticosterone [50-22-6]; Down 200; 11.6uM; PC3; HT_HG-U133A	FLI1 AMPD3 CTIF ECE1 TFAP2A ARHGEF10L SLC9A2 KCNMA1	4.04e-05	199	144	8	4064_DN
Drug	Sulfapyridine [144-83-2]; Down 200; 16uM; PC3; HT_HG-U133A	RC3H2 ATAD5 DIPK1A TFAP2A LINS1 VPS13D EHHADH CCSER2	4.18e-05	200	144	8	7151_DN
Disease	Adenoid Cystic Carcinoma	KMT2C NETO2 PRKDC ATM TOP2A	1.48e-04	100	147	5	C0010606
Disease	Bilateral Wilms Tumor	AMER1 MAP3K4 BRCA2	4.03e-04	29	147	3	C2930471
Disease	FEV/FEC ratio	STARD13 BOC TET2 AMPD3 DIPK1A SH3BP2 SLC35B3 ANKS1B CEMIP2 DST KLHL7 COPS8 NETO1 CCSER2 RAI14 PLCL1	4.29e-04	1228	147	16	EFO_0004713
Disease	obsessive-compulsive symptom measurement	TMEM63C TAAR3P LARGE1	4.92e-04	31	147	3	EFO_0007802
Disease	disease of cellular proliferation (implicated_via_orthology)	JAK3 ATM	5.09e-04	7	147	2	DOID:14566 (implicated_via_orthology)
Disease	infertility (implicated_via_orthology)	BRCA2 ATM	5.09e-04	7	147	2	DOID:5223 (implicated_via_orthology)
Disease	aspergillosis (is_implicated_in)	TLR6 TLR1	6.77e-04	8	147	2	DOID:13564 (is_implicated_in)
Disease	female breast cancer (is_implicated_in)	FANCI ATM	6.77e-04	8	147	2	DOID:0050671 (is_implicated_in)
Disease	Nephroblastoma	AMER1 MAP3K4 BRCA2	7.67e-04	36	147	3	C0027708
Disease	endometrial cancer (is_implicated_in)	MLH3 BRCA2 ATM	7.67e-04	36	147	3	DOID:1380 (is_implicated_in)
Disease	facial depth measurement	TRPC6 TRPM1	8.67e-04	9	147	2	EFO_0007857
Disease	colorectal cancer	STARD13 BOC TET2 AMPD3 ABCA12 TRPC6 ADGRB3 PIWIL4 C8orf34 PLCL1	9.30e-04	604	147	10	MONDO_0005575
Disease	colorectal cancer, colorectal adenoma	STARD13 BOC TET2 TRPC6 PLCL1	1.01e-03	152	147	5	EFO_0005406, MONDO_0005575
Disease	Peripheral T-Cell Lymphoma	TET2 ATM	1.08e-03	10	147	2	C0079774
Disease	Fanconi anemia (is_implicated_in)	BRCA2 FANCI	1.08e-03	10	147	2	DOID:13636 (is_implicated_in)
Disease	colorectal cancer (is_marker_for)	TET2 AMER1 SMC2 BRCA2 ATM	1.16e-03	157	147	5	DOID:9256 (is_marker_for)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	TET2 KMT2C BRCA2	1.47e-03	45	147	3	DOID:3748 (is_implicated_in)
Disease	nicotine dependence (implicated_via_orthology)	TRPC7 TRPC6	1.57e-03	12	147	2	DOID:0050742 (implicated_via_orthology)
Disease	Oligospermia	PIWIL4 BRWD1	1.57e-03	12	147	2	C0028960
Disease	Medulloblastoma	FLI1 BRCA2 ATM	2.00e-03	50	147	3	C0025149
Disease	forced expiratory volume	BOC TET2 AMPD3 ATAD5 TRIM39 CEP63 SLC9A2 DST CELF1 KCNMA1 PLCL1	2.06e-03	789	147	11	EFO_0004314
Disease	Fanconi anemia	BRCA2 FANCI	2.16e-03	14	147	2	cv:C0015625
Disease	Cleft palate, cleft lip	ADGRB3 SFI1 TFAP2A SLC39A12 NETO1 TLN2	2.82e-03	279	147	6	EFO_0003959, HP_0000175
Disease	executive function measurement	TET2 DPPA2 ADGRB3 ANKS1B GFRA2 ARHGEF10L POLR3A	2.86e-03	376	147	7	EFO_0009332
Disease	age at menarche	TET2 TRPC6 KBTBD2 RGS4 DST ZFHX4 CELF1 PLCL1 BRWD1	3.02e-03	594	147	9	EFO_0004703
Disease	Bardet-Biedl syndrome 1 (disorder)	WDPCP BBS12	3.19e-03	17	147	2	C2936862
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR6 TLR1	3.19e-03	17	147	2	DOID:8677 (biomarker_via_orthology)
Disease	Bone marrow hypocellularity	BRCA2 FANCI	3.58e-03	18	147	2	C1855710
Disease	Bardet-Biedl syndrome	WDPCP BBS12	3.58e-03	18	147	2	cv:C0752166
Disease	Prostatic Neoplasms	TET2 TCP1 TLR6 KMT2C BRCA2 EHHADH PRKDC ATM TOP2A	3.84e-03	616	147	9	C0033578
Disease	Malignant neoplasm of prostate	TET2 TCP1 TLR6 KMT2C BRCA2 EHHADH PRKDC ATM TOP2A	3.84e-03	616	147	9	C0376358
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	MLH3 ATM	3.99e-03	19	147	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	MLH3 ATM	3.99e-03	19	147	2	C2936783
Disease	Disorder of eye	WDPCP KLHL7 FSCN2 TRPM1 BBS12	4.28e-03	212	147	5	C0015397
Disease	Severe Combined Immunodeficiency	JAK3 PRKDC	4.42e-03	20	147	2	C0085110
Disease	Adenocarcinoma of prostate	BRCA2 ATM	4.42e-03	20	147	2	C0007112
Disease	allergic rhinitis	BOC LAMA3 TLR1 PLCL1	4.48e-03	133	147	4	EFO_0005854
Disease	MYELODYSPLASTIC SYNDROME	TET2 BRCA2 FANCI	4.60e-03	67	147	3	C3463824
Disease	BREAST CANCER	BRCA2 ATM	4.86e-03	21	147	2	114480
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	KCNMA1 BRWD1	4.86e-03	21	147	2	EFO_0004616, EFO_0010726, EFO_1000786

Protein segments in the cluster

Peptide	Gene	Start	Entry
DASAATKSMNCLARK	ATAD5	1536	Q96QE3
NFTSAMSIIKKACLT	ARHGEF10L	416	Q9HCE6
AQKDKMFSQNDTRCA	LRG1	316	P02750
CEMDVAKSFTQNKDL	PRMT9	476	Q6P2P2
SFAFTAAKLCDKMAL	CTIF	426	O43310
QSIEELKDNFKLMCT	BRD7	191	Q9NPI1
SMNELSNPCLKKENS	ADGRB3	1261	O60242
QQLMEDKTSRFTCKG	ADH4	126	P08319
SKKCTENDIRVMFSS	CELF1	116	Q92879
DAMKEFCNLSLSERS	ABCA12	616	Q86UK0
LSETCFQLKKQMLES	GZF1	121	Q9H116
AIMATATSRNCDKLK	SH3BP2	321	P78314
KKLLAAMLSQDSFES	C8orf34	331	Q49A92
NMLLATKQICKEFTD	TFAP2A	336	P05549
KKDQSTCLMQLFQSD	AMER1	711	Q5JTC6
KSMAAFKNLSAQCQE	ARHGEF7	436	Q14155
TKSCMLQADSEKLRQ	ACAP2	336	Q15057
NKEEKIQLAYAMSCS	LVRN	851	Q6Q4G3
NIFDCMDSTKTFSQL	BBS12	136	Q6ZW61
KDKLSASFCQTLKAM	ADAMTS12	1541	P58397
LCNELSFLSDAMKSE	AMPD3	746	Q01432
CFKVTKRDEDSSLMQ	RC3H2	251	Q9HBD1
VLQMQCKLFVFDKTS	RANBP3	401	Q9H6Z4
ENQCSLDMKSKLNTS	RC3H1	1046	Q5TC82
SSYCSVIENMNKEKA	RAI14	581	Q9P0K7
SACLLSDMESFKAAN	RAB3GAP1	676	Q15042
LKAKFCSTVANDVML	NETO1	246	Q8TDF5
KHKNCMESFLEAASL	JAK3	561	P52333
ENFLCDLMDTAVTKK	ANKS1B	451	Q7Z6G8
VSTQAFCSMKRKDIS	OTOA	471	Q7RTW8
ENSREDALFCKSLMN	FANCI	1016	Q9NVI1
SMSRDNKFSKKDCLS	PARP15	61	Q460N3
SKLTEMPAKSFNQCV	KLHL31	346	Q9H511
CLKTLKEEFQQDMSR	LARGE1	726	O95461
LFSSSDKFTLNQDMC	KMT2C	946	Q8NEZ4
SAKVDSKLICMFQNS	LINS1	126	Q8NG48
SKLICMFQNSDKLLS	LINS1	131	Q8NG48
SMDKSLEFITNCGKN	LAMA3	1221	Q16787
KECILASLNIKSMQF	KCNMA1	941	Q12791
NKCEAPALSFSDKTM	DST	2251	Q03001
KNMDGTFNVTSCLKL	NCR3LG1	201	Q68D85
TFSCGDKLTLDQLKM	IL12RB2	841	Q99665
MDQDSLSSSLKTCYK	FDFT1	31	P37268
FNSITMKDEDLINKC	TMEM63C	111	Q9P1W3
MSLKKQVFAELSAVC	EHHADH	386	Q08426
DNKFIACLMSTKTEE	MLH3	1196	Q9UHC1
EKKTISFQGCMAQLF	OR4A15	116	Q8NGL6
LVNEKDASCKRNAFM	COPB1	181	P53618
LKSHMENTFKCNDKA	KIF20B	786	Q96Q89
KRMTSQDCLETSKND	MDM1	556	Q8TC05
DLFSCEELKQSAKRM	KBTBD2	141	Q8IY47
NSRSSLNAKMEECVK	KCND2	571	Q9NZV8
DKACNLMIFDTRKTA	MANSC1	76	Q9H8J5
VADNMELSKSATCKN	KNL1	1056	Q8NG31
KMCVDFLKEQVDASN	KLHL7	131	Q8IXQ5
EEALSNCMQADKTKA	JAKMIP1	166	Q96N16
TSCGIKKIMFQTNDD	OOSP4B	61	A0A2R8Y4Y8
KMALCTNNITDFTVK	ELAPOR2	726	A8MWY0
KVEKCAMISSFLDQQ	MED14	111	O60244
KKQLSAMNSDELISF	MORC2	931	Q9Y6X9
KDVKTALQRFMTNLC	OR8J1	296	Q8NGP2
KSINCEKMVRSQSFS	CCSER2	211	Q9H7U1
QNKLCFIQFTKKMES	WDPCP	181	O95876
NSCHKVMEFKSLLLS	DNAH1	3806	Q9P2D7
LMNDIADICKSLASF	ATM	811	Q13315
SQQFSECMDLALKSL	IL31	141	Q6EBC2
SAKKCAQDYNMLSDD	ICE2	156	Q659A1
FSNVMICETKARKSS	BOC	801	Q9BWV1
SELKDMFRKFIQACS	DOCK11	1981	Q5JSL3
EMEKTCSKEFKLSNN	BRCA2	2121	P51587
KANNSKELSMCFTEL	GFRA2	411	O00451
ILNCMAVKLSDSEFK	EFCAB6	431	Q5THR3
SATCKQLSQELMEKY	CEP63	361	Q96MT8
CEVESKSQAFNMKQD	BORA	526	Q6PGQ7
TMQLCANKLDKKDFF	CPNE9	151	Q8IYJ1
ELCKMNKEDFLRATT	FLI1	166	Q01543
FKSKFSDQTVIKMCQ	GIMAP8	36	Q8ND71
SDMQACSQDKAKISL	CEP350	961	Q5VT06
AATDSKDISNCMAKA	CEMIP2	1156	Q9UHN6
CAATAANKIKLMSDV	BRWD1	1931	Q9NSI6
NSNSSCMELSKKIAE	PRPSAP2	26	O60256
MAESAFSFKKLLDQC	COPS8	6	Q99627
CKSAKDNSMTLLQAT	CYP39A1	236	Q9NYL5
KNSSVEAFKRQTECM	ECE1	631	P42892
LKDKEDNCMVNSNLS	FAM135B	441	Q49AJ0
LQNSTLMAEFSKLCS	GRIPAP1	91	Q4V328
LMCDTSAKNLGYNDK	DIPK1A	291	Q5T7M9
NMFKTCRLAKELLDS	RUBCN	821	Q92622
EEICSSKLNMSNKEY	SLC39A12	126	Q504Y0
AKSSMVIKVDFCADQ	CFAP47	196	Q6ZTR5
LCALSFQKSTMESKD	INAVA	76	Q3KP66
RDVATMQFCANKLDK	CPNE5	176	Q9HCH3
MSDANLDSSKKNFLE	DPPA2	1	Q7Z7J5
KSMANQLLAKFEEST	MICAL2	716	O94851
TAMCNEVASLSKKFT	FAM114A1	491	Q8IWE2
IEKKLAFDMATNAAC	OSTF1	171	Q92882
EQLKMDFNDSASLSK	POTEA	446	Q6S8J7
SNVMDVKDRSFLKSC	P2RX5	206	Q93086
TFLMQIDQETKKCTF	FSCN2	291	O14926
DRKKNVQCSFMLDSV	MAP3K4	156	Q9Y6R4
MKNLLTEKCISSHNF	SFI1	1	A8K8P3
TKMTNSTIKQLLAFC	TAAR3P	141	Q9P1P4
NTLNKCASMKLDVNF	STARD13	111	Q9Y3M8
CLQSGFEMLKDVKST	TRIM39	251	Q9HCM9
ITCFDEAQKKIFNLM	RGS4	146	P49798
NTEKSNMLEFKLCPD	RESF1	1626	Q9HCM1
TAQDKAVKCNMDSLR	TDRD12	286	Q587J7
NEDAKAAMTELKSCR	SCGB1C2	56	P0DMR2
NKQDFMDLSICTREK	PIWIL4	76	Q7Z3Z4
SIMKKSEFLCCQDSF	POLR3A	951	O14802
IECSKITMDLKFNNS	SLC35B3	26	Q9H1N7
DCLINAAKTSMSSKI	TCP1	146	P17987
LKAKFCSTVANDVML	NETO2	251	Q8NC67
MNFSEVFKLSSLLCK	WRAP73	1	Q9P2S5
VCNDLSIMSKFKLLS	HERC2P3	251	Q9BVR0
DVDIRFSKTMNSCKV	RASGRF1	631	Q13972
LDDLNNKKDSCMSNH	SCN1A	1051	P35498
SADFFQSCQKMRSIK	TLR1	506	Q15399
SSIMKCDTDIQNKLY	ACTRT1	281	Q8TDG2
AVCSKRDFMLITNKS	CHURC1	31	Q8WUH1
ESKMACAAQNASLLK	CLEC12A	156	Q5QGZ9
DIQAFFMSIDSLCKK	RNF212	61	Q495C1
SEKKISSANDCISFM	PLCL1	101	Q15111
MSNLQLKVLKACFSD	ZFHX4	2891	Q86UP3
LFFSQINMCESKEKT	RGS18	6	Q9NS28
NKLCVSALAMDSFAE	PHLPP2	796	Q6ZVD8
LFKSFCQMKTIETID	SLC9A2	256	Q9UBY0
FKCFTKKMDDSALQL	SNX18	431	Q96RF0
EMCKDSQLEFKRVSA	TECPR1	26	Q7Z6L1
MDTSSKENIQLFCKT	SLCO1C1	1	Q9NYB5
FLETCLEKMQKDTSA	TTBK2	466	Q6IQ55
NDMDKQKSTLVDALC	TPP2	1111	P29144
FFTTCSDLNMLKKLK	THUMPD2	51	Q9BTF0
KAMLVCSDAATNKNF	SEMA7A	286	O75326
NEDAKAAMTELKSCI	SCGB1C1	56	Q8TD33
TTFVCDNMDNAKKVA	SMC2	626	O95347
ILMKSCLAFKNDATE	SOSTDC1	16	Q6X4U4
SADFFQSCQKMRSIK	TLR6	511	Q9Y2C9
DCMKKFLDALELSQS	PRKDC	1741	P78527
DETINACKTMKSRSF	TRPM1	1426	Q7Z4N2
CITFQPDLSKFKMQS	TOP2A	216	P11388
KAVSDMLTACKQASF	TLN2	2211	Q9Y4G6
NKFMSVLDTNKDCEV	S100A3	56	P33764
STDNAKQLFRMKTSC	TRPC6	476	Q9Y210
LECMKNNLPSNDSSK	UBTF	31	P17480
KLAAMLNTCSFQKPE	TET2	306	Q6N021
KMLEESKTLNFNCVD	TRPC7	61	Q9HCX4
ERSKQECFLNLKMAS	VPS13D	1276	Q5THJ4
IMSQCFDRSELSDKK	MYO1C	581	O00159